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Arterial Disorders : Definition, Clinical Manifestations, Mechanisms and Therapeutic Approaches

https://libcat.nshealth.ca/en/permalink/provcat39194
Adel Berbari, Giuseppe Mancia, editors. --Cham: Springer , c2015.
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As our knowledge about arterial disease is greatly expanding, the aim of this book is to explore all aspects of arterial pathology, including classification, clinical manifestations, pathogenesis, and therapeutic options. The discussion of pathophysiologic mechanisms of arterial disease is wide ranging, encompassing hemodynamic, metabolic, humoral, inflammatory, genetic and environmental factors. Particular emphasis is placed on recent concepts, such as: the role of age-associated arterial alte…
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Other Authors
Berbari, Adel
Mancia, Giuseppe
Responsibility
Adel Berbari, Giuseppe Mancia, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2015
Physical Description
1 online resource (ix, 431 p. : 61 illus., 41 illus. in color)
ISBN
9783319145563
9783319145556 (print ed.)
Subjects (MeSH)
Arteriosclerosis
Microcirculation
Abstract
As our knowledge about arterial disease is greatly expanding, the aim of this book is to explore all aspects of arterial pathology, including classification, clinical manifestations, pathogenesis, and therapeutic options. The discussion of pathophysiologic mechanisms of arterial disease is wide ranging, encompassing hemodynamic, metabolic, humoral, inflammatory, genetic and environmental factors. Particular emphasis is placed on recent concepts, such as: the role of age-associated arterial alterations in the initiation and progression of cardiovascular diseases in older persons, the importance of mineral metabolism-bone vascular interactions, the clinical and prognostic significance of the renal resistive index, retinal circulation, toxemia of pregnancy as an arterial disease, and the role of pulmonary/vascular interaction in pulmonary hypertension and cross-talk of macrocirculation and microcirculation in target organ involvement. Evaluation procedures are carefully explained, and the full range of currently available therapeutic options, including lifestyle modifications and pharmacologic approaches, are described and appraised.
Contents
[publisher supplied] PART I. Introduction: Definition and epidemiology of arterial disease -- PART II. Normal structure and physiology of the arterial system -- PART III. Classification of arterial pathology and clinical manifestations: Atherosclerosis -- Arteriosclerosis -- Disease of Precapillary resistance vessels -- PART IV. Pathogenetic mechanisms in arterial disease: Hemodynamic and mechanical factors -- Metabolic factors -- Inflammatory markers -- Neurohormonal interactions -- Mineral-bone/ arterial interactions -- Endothelial function and impairment -- Miscellaneous: Pharmacologic/factors/environmental factors -- PART V. Systemic arterial disorders: Arterial aging -- Diabetes mellitus -- Metabolic Syndrome/obesity -- Chronic kidney disease/Renovascular interactions -- Pulmonary Hypertension/Pulmonary vascular interactions -- Systemic vasculitides -- Genetic/ degenerative disorders -- Hypertension -- Toxemia of pregnancy -- Kidney transplants, both donors and recipients -- PART VI. Evaluation procedures: Arterial function -- Renal resistive index -- Retinal microcirculation -- PART VII. Therapeutic options: Lifestyle modifications -- Pharmacologic approaches.
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e-Book
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Assessment of Preclinical Organ Damage in Hypertension

https://libcat.nshealth.ca/en/permalink/provcat39219
Enrico Agabiti Rosei, Giuseppe Mancia, editors. --Cham: Springer , c2015.
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This book presents up-to-date information on how to assess early preclinical alterations in the heart, the small and large arteries and the kidney in the general and the hypertensive population, using the most sensitive, specific and cost-effective techniques. A wide variety of techniques are discussed, with careful attention to the latest developments. For each organ, evidence is documented regarding the prevalence of organ damage. Information is provided on the potential induction of regressi…
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Agabiti Rosei, Enrico
Mancia, Giuseppe
Responsibility
Enrico Agabiti Rosei, Giuseppe Mancia, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2015
Physical Description
1 online resource (viii, 218 p. : 44 illus., 28 illus. in color)
ISBN
9783319156033
9783319156026 (print ed.)
Subjects (MeSH)
Cardiovascular Diseases - diagnosis
Cerebrovascular Disorders - diagnosis
Diagnostic Techniques, Cardiovascular
Hypertension - complications
Hypertension - therapy
Kidney Function Tests - methods
Prodromal Symptoms
Abstract
This book presents up-to-date information on how to assess early preclinical alterations in the heart, the small and large arteries and the kidney in the general and the hypertensive population, using the most sensitive, specific and cost-effective techniques. A wide variety of techniques are discussed, with careful attention to the latest developments. For each organ, evidence is documented regarding the prevalence of organ damage. Information is provided on the potential induction of regression of organ damage by treatment, the criteria for establishing significant changes and the clinical prognostic significance of regression. The manual will be invaluable for all practitioners responsible for the clinical management of hypertensive patients, given that the assessment of early preclinical cardiovascular and renal damage permits more accurate risk stratification at baseline and facilitates evaluation of cardiovascular protection when regression of structural changes is achieved during treatment.
Contents
PART I: HEART 1 Electrocardiography -- 2 Echocardiography -- 3 New techniques: 3D, CT, MRI -- PART II: LARGE ARTERIES 4 Ultrasound of Carotid IMT and plaque -- 5 Ultrasound of the Aorta/coronary arteries -- Pulse wave velocity and central BP -- 7 Ankle-brachial index -- 8 Atherosclerosis and general principles of arterial imaging -- 9 Imaging and ageing of the aorta and large arteries in the lower extremities -- PART III: SMALL ARTERIES 10 Micro myography -- 11 Damage of the retinal arterioles -- 12 Capillaroscopy -- 13 Other techniques for assessment -- PART IV: KIDNEY 14 Proteinuria -- 15 Glomerular Filtration Rate -- 16 Other techniques -- PART V: BRAIN 17 RMN/TC: Evaluation of Brain damage -- 18 Questionnaires for cognitive function -- 19 Other techniques for neurological damage -- 20 Relation between blood pressure and markers of organ damage.
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e-Book
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Cardiorenal Syndrome : Mechanisms, Risk and Treatment

https://libcat.nshealth.ca/en/permalink/provcat29194
edited by Adel E. Berbari, Giuseppe Mancia. --Milan: Springer-Verlag , c2010.
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Author
Berbari, Adel E
Other Authors
Mancia, Giuseppe
Responsibility
edited by Adel E. Berbari, Giuseppe Mancia
Place of Publication
Milan
Publisher
Springer-Verlag
Date of Publication
c2010
ISBN
9788847014633
Subjects (MeSH)
Cardiovascular Diseases - complications
Cardiovascular Diseases - physiopathology
Kidney Failure, Chronic - complications
Kidney Failure, Chronic - physiopathology
Subjects (LCSH)
Cardiology
Nephrology
Format
e-Book
Location
Online
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Disorders of Blood Pressure Regulation : Phenotypes, Mechanisms, Therapeutic Options

https://libcat.nshealth.ca/en/permalink/provcat43028
Adel E. Berbari, Giuseppe Mancia, editors. --Cham: Springer , c2018.
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This book aims to present a comprehensive classification of hypertensive phenotypes based on underlying target organ involvement. Particular emphasis is placed on review and assessment of clinical presentation, pathophysiologic mechanisms, and possible specific therapeutic options for each hypertension phenotype. Several of these phenotypes are well known and well described in the literature, such as prehypertension, white coat and masked hypertension, isolated systolic hypertension, renovascul…
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Other Authors
Berbari, Adel E.
Mancia, Giuseppe
Responsibility
Adel E. Berbari, Giuseppe Mancia, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2018
Physical Description
1 online resource (xi, 880 p.) : 131 illus., 53 illus. in color
Series Title
Updates in Hypertension and Cardiovascular Protection
ISBN
9783319599182
9783319599175 (print ed.)
9783319599199 (print ed.)
9783319867342 (print ed.)
ISSN
2366-4606
Subjects (MeSH)
Hypertension - etiology
Phenotype
Specialty
Cardiology
Physiology
Abstract
This book aims to present a comprehensive classification of hypertensive phenotypes based on underlying target organ involvement. Particular emphasis is placed on review and assessment of clinical presentation, pathophysiologic mechanisms, and possible specific therapeutic options for each hypertension phenotype. Several of these phenotypes are well known and well described in the literature, such as prehypertension, white coat and masked hypertension, isolated systolic hypertension, renovascular hypertension, endocrine hypertension, pediatric hypertension, and gestational hypertension. Other hypertension phenotypes, however, are not widely recognized, being reported only in special reviews; examples include hypertension associated with renal calculus disease and other rarer causes such as Turner syndrome, herbal and medicinal compounds, and pharmacologic agents. A detailed account of the various causes of monogenic hypertension is also included. Finally, a section is devoted to general aspects of hypertension, including the significance of blood pressure indices, the natural course of untreated and treated hypertension, hypertension mechanisms, genetics, and guidelines for blood pressure control.
Contents
Part I: General Aspects -- 1. Introduction: Definition and Classification of Arterial Pressure Phenotypes -- 2. Diagnostic and Prognostic Significance of Blood Pressure Indices -- 3. Role of Circadian Rhythms and Seasonal Variation in BP Levels -- 4. Natural History of Treated and Untreated Hypertension -- Part II: Mechanisms of Hypertension Development -- 5. The Kidneys, Volume and Blood Pressure Regulation, and Hypertension -- 6. Nervous System -- 7. Hormonal Systems -- 8. Vasoactive Peptides -- 9. Endothelial Function -- 10. Genetics of Blood Pressure and Hypertension -- Part III: Hypertension Phenotypes: Monogenic Syndromes -- 11. Monogenic Forms of Hypertension -- 12. Arterial Hypertension in Turner Syndrome -- Part IV: Hypertension Phenotypes: The Heart -- 13. Hypertensive Heart Disease -- 14. Perioperative Cardiac Surgery Hypertension -- 15. Hypertension: Supravalvular Aortic Stenosis -- 16. Coarctation of the Aorta -- 17. Atrial Fibrillation and Hypertension: Two Entities That Usually Coexist -- Part V: Hypertension Phenotypes: The Central Nervous System and the Brain -- 18. Sleep Disturbances/Sleep Apnea -- 19. Stress and Hypertension -- 20. Central Nervous System Disorders: Transient Ischemic Attack and Stroke (Ischemic/Hemorrhagic) -- Part VI: Hypertension Phenotypes: The Kidney -- 21. Chronic Kidney Disease -- 22. Calculus Renal Disease -- 23. Uric Acid-Hypertension Relationships -- 24. Hypertension in Dialysis Patients: Clinical Edidemiology, Pathogenesis, Diagnosis, and Treatment -- 25. Renovascular Hypertension -- 26. Molecular Pathways in Hypertensive Renal Damage -- 27. Determinants of Hypertensive Renal Disease and Its Progression -- Part VII: Hypertension Phenotypes: Endocrine Causes -- 28. Cushing's Syndrome and Glucocorticoid Excess -- 29. Primary Aldosteronism and Its Various Scenarios -- 30. Severe Paroxysmal Hypertension (Pseudopheochromocytoma) -- 31. Paroxysmal Hypertension: Pheochromocytoma -- 32. Hypertension in Thyroid Disorders -- 33. Primary Hyperparathyroidism -- Part VIII: Special Types of Hypertension -- 34. Phenotypic Changes in the Transition from Prehypertension to Established Hypertension -- 35. White Coat and Masked Hypertension -- 36. Isolated Systolic Hypertension: In the Young and in the Elderly -- 37. Treatment of Resistant Hypertension -- 38. Accelerated / Malignant Hypertension -- 39. Nocturnal Hypertension -- 40. Salt and Hypertension -- 41. Diabetes Mellitus and Hypertension -- 42. Obesity and Metabolic Syndrome Hypertension -- 43. Secondary Hypertension: Infrequently Considered Aspects: Illicit/Recreational Substances, Herbal Remedies, and Drug-Associated Hypertension -- Part IX: Hypertensive Phenotypes: Blood Pressure Disorders of Pregnancy and Pediatric Hypertension -- 44. Hypertensive Disorders of Pregnancy -- 45. Blood Pressure Trends in Children and Adolescents: Predictors of Blood Pressure Elevation in Children and Adolescents -- 46. Hypertension in Children and Adolescents -- Part X: Management and Therapeutic Approaches -- 47. What Is New and What Is Different in Recent Guidelines on Antihypertensive Treatment? Looking Forward to Guidelines Reappraisal -- 48. Place of Invasive Procedures in Blood Pressure Control -- 49. Is Hypertension-Related Target Organ Involvement/Damage Reversible/Preventable?
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e-Book
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Online
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Home Blood Pressure Monitoring

https://libcat.nshealth.ca/en/permalink/provcat44952
George S. Stergiou, Gianfranco Parati, Giuseppe Mancia, editors. --Cham: Springer , c2020.
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Hypertension remains a leading cause of disability and death worldwide. Self-monitoring of blood pressure by patients at home is currently recommended as a valuable tool for the diagnosis and management of hypertension. Unfortunately, in clinical practice, home blood pressure monitoring is often inadequately implemented, mostly due to the use of inaccurate devices and inappropriate methodologies. Thus, the potential of the method to improve the management of hypertension and cardiovascular dise…
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Stergiou, George S.
Parati, Gianfranco
Mancia, Giuseppe
Other Authors
European Society of Hypertension
Responsibility
George S. Stergiou, Gianfranco Parati, Giuseppe Mancia, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2020
Physical Description
1 online resource (viii, 174 p.) : 25 illus., 9 illus. in color
Series Title
Updates in hypertension and cardiovascular protection
ISBN
9783030230654
9783030230647 (Print ed.)
9783030230661 (Print ed.)
9783030230678 (Print ed.)
ISSN
2366-4606
Subjects (MeSH)
Blood Pressure Determination - methods
Blood Pressure Monitoring, Ambulatory
Hypertension - prevention & control
Specialty
Cardiology
Monitoring, Physiologic
Abstract
Hypertension remains a leading cause of disability and death worldwide. Self-monitoring of blood pressure by patients at home is currently recommended as a valuable tool for the diagnosis and management of hypertension. Unfortunately, in clinical practice, home blood pressure monitoring is often inadequately implemented, mostly due to the use of inaccurate devices and inappropriate methodologies. Thus, the potential of the method to improve the management of hypertension and cardiovascular disease prevention has not yet been exhausted. This volume presents the available evidence on home blood pressure monitoring, discusses its strengths and limitations, and presents strategies for its optimal implementation in clinical practice. Written by distinguished international experts, it offers a complete source of information and guide for practitioners and researchers dealing with the management of hypertension.
Contents
1. Devices for Home Blood Pressure Monitoring -- 2. Cuff Design for Home Blood Pressure Monitors -- 3. Home Blood Pressure and Preclinical Organ Damage -- 4. Home Blood Pressure as Predictor of Adverse Health Outcomes -- 5. Diagnostic Value of Home Blood Pressure -- 6. Home Blood Pressure Monitoring Schedule -- 7. Home Blood Pressure Monitoring for Treatment Titration -- 8. Home Blood Pressure Monitoring, Treatment Adherence and Hypertension Control -- 9. Home Blood Pressure Monitoring: Cost-Effectiveness, Patients’ Preference and Barriers for Clinical Use -- 10. Home Blood Pressure Monitoring in Clinical Research -- 11. Home Blood Pressure Telemonitoring: Conventional Approach and Perspectives from Mobile Health Technology -- 12. Nocturnal Home Blood Pressure Monitoring -- 13. Home Blood Pressure Monitoring in Children, Pregnancy, and Chronic Kidney Disease -- 14. Home Blood Pressure Variability -- 15. Home Versus Ambulatory Blood Pressure Monitoring -- 16. Guidelines for Home Blood Pressure Monitoring.
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e-Book
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Online
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Hypertension and Heart Failure : Epidemiology, Mechanisms and Treatment

https://libcat.nshealth.ca/en/permalink/provcat44322
Maria Dorobantu, Giuseppe Mancia, Guido Grassi, Victor Voicu, editors. --Cham: Springer , 2019.
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This book explains how hypertension affects 20-50% of the adult population in developed countries. Heart failure is the result of the hypertension's effects on the heart and it represents a growing public health problem. In this context the international scientific community is continuously struggling to develop better strategies in screening, diagnosing and treating hypertension and its deleterious effects. Thus, this field is continuously changing, with new important information being added c…
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Dorobantu, Maria
Mancia, Giuseppe
Grassi, Guido
Voicu, Victor
Responsibility
Maria Dorobantu, Giuseppe Mancia, Guido Grassi, Victor Voicu, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
2019
Physical Description
1 online resource (ix, 416 p.) : 54 illus., 37 illus. in color
Series
Updates in Hypertension and Cardiovascular Protection
Series Title
Updates in hypertension and cardiovascular protection
ISBN
9783319933207
9783319933191 (Print ed.)
9783319933214 (Print ed.)
ISSN
2366-4606
Subjects (MeSH)
Hypertension - epidemiology
Hypertension - physiopathology
Heart Failure - etiology
Heart Failure - therapy
Specialty
Cardiology
Abstract
This book explains how hypertension affects 20-50% of the adult population in developed countries. Heart failure is the result of the hypertension's effects on the heart and it represents a growing public health problem. In this context the international scientific community is continuously struggling to develop better strategies in screening, diagnosing and treating hypertension and its deleterious effects. Thus, this field is continuously changing, with new important information being added constantly. This volume will offer both insights into the intimate mechanisms of transition from hypertension to heart failure and clinical practice advice on the prevention and treatment of heart failure in hypertensive population. The mechanisms which explain the progression from hypertension to heart failure will be also covered exhaustively by offering two chapters referring to the diagnosis of heart failure in hypertensive population and one regarding echocardiography which is the most frequently used imaging method in clinical practice. The reader will be also provided with information on cardiovascular magnetic resonance which has the unique advantage of differentiating hypertensive heart failure from other pathologies associated with increased myocardial thickness. This book is a useful tool for clinicians but also to the research community interested in heart failure and consequences of hypertension on heart who want to be up-to-date with the new developments in the field.
Contents
Part I. Epidemiological Aspects -- 1. Epidemiological Aspects (Prevalence and Risk of Heart Failure Related to Blood Pressure) -- Part II. Mechanisms of Heart Failure in Arterial Hypertension -- 2. Genetics of Hypertension and Heart Failure -- 3. Blood Pressure Variability and Blood Pressure Load -- 4. Hemodynamic Mechanisms -- 5. Neural Mechanisms -- 6. Natriuretic Peptides -- 7. Renal Mechanisms and Heart Failure -- 8. Heart Failure and Metabolic Factors -- 9. Role of Central Blood Pressure and Arterial Stiffening -- 10. Pathophysiology of Hypertensive Heart Disease -- Part III. Diagnosis of Heart Failure in Hypertensive Patients -- 11. Role of Echocardiography -- 12. The Additive Value of Cardiovascular Magnetic Resonance Imaging in Hypertensive Heart Disease -- 13. Biomarkers -- Part IV. Complications of Hypertensive Heart Disease -- 14. Atrial Fibrillation and Other Arrhythmias in Hypertensive Heart Disease -- 15. Arterial Hypertension and Flash Pulmonary Edema -- 16. The Role of Drug Therapy in Lowering Mortality and Morbidity: From Established Heart Failure to High-Risk Hypertension -- Part V. Prevention of Heart Failure in Hypertension -- 17. Non-pharmacological Treatment -- 18. Blood Pressure-Lowering Treatment and the Prevention of Heart Failure: Differences and Similarities of Antihypertensive Drug Classes -- 19. Regression Under Treatment of Left Ventricular Hypertrophy and Other Structural Alterations -- Part VI .Treatment of Heart Failure in Hypertensive Patients -- 20. New Drugs for the Hypertensive Failing Heart -- 21. Heart Failure with Preserved Ejection Fraction: Current Management and Future Strategies -- 22. Treatment of Acute Heart Failure in Hypertensive Crisis -- Part VII. Invasive Approaches -- 23. Carotid Baroreceptor Stimulation -- 24. Renal Nerve Ablation -- Part VIII. Hypertension, Heart Failure and Guidelines -- 25. Prevention and Treatment of Heart Failure in Hypertension Guidelines.
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e-Book
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Online
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Interventional Therapies for Secondary and Essential Hypertension

https://libcat.nshealth.ca/en/permalink/provcat40258
Costas Tsioufis, Roland E. Schmieder, Giuseppe Mancia, editors. --Cham: Springer , c2016.
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This book aims to describe the role of interventional therapies in various forms of secondary hypertension and to explain the ability of such approaches to address unmet needs in the setting of uncontrolled essential hypertension. The coverage encompasses interventions in the full range of relevant conditions, including the various specific pathologies responsible for secondary hypertension, such as renal artery stenosis, coarctation of the aorta, and adrenal tumors. In each case, up-to-date in…
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Other Authors
Tsioufis, Costas
Schmieder, Roland E
Mancia, Giuseppe
Responsibility
Costas Tsioufis, Roland E. Schmieder, Giuseppe Mancia, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2016
Physical Description
1 online resource (x, 363 p. : 19 illus., 13 illus. in color)
Series Title
Updates in Hypertension and Cardiovascular Protection
ISBN
9783319341415
9783319341408 (print ed.)
ISSN
2366-4606
Subjects (MeSH)
Hypertension - therapy
Renal Artery - innervation
Sympathectomy
Abstract
This book aims to describe the role of interventional therapies in various forms of secondary hypertension and to explain the ability of such approaches to address unmet needs in the setting of uncontrolled essential hypertension. The coverage encompasses interventions in the full range of relevant conditions, including the various specific pathologies responsible for secondary hypertension, such as renal artery stenosis, coarctation of the aorta, and adrenal tumors. In each case, up-to-date information is presented on indications, procedural aspects, and patient follow-up. A further focus is the most recent knowledge on the use of invasive neuromodulation, such as renal sympathetic denervation and baroreflex stimulation. The text is supplemented by helpful explanatory diagrams and treatment algorithms. A comprehensive clinical guide of this nature has to date been absent from the literature. The book will be of interest to clinicians managing hypertensive patients, researchers investigating advanced hypertension management, and students on cardiology courses.
Contents
Part I. Interventions for Secondary Hypertension -- 1. Interventions for Renovascular Hypertension -- 2. Primary Aldosteronism: A Field on the Move -- 3. Pheochromocytoma/Paragangliomas -- 4. Coarctation of the Aorta -- Part II Adjunctive Therapies -- 5. Sleep Apnea -- Part III. Interventions for Essential Hypertension -- 6. The Impact of Uncontrolled Hypertension on the Cerebrovascular System -- 7. The Impact of Uncontrolled Hypertension on the Heart -- 8. Optimization of Antihypertensive Drug Treatment in Resistant Hypertension -- 9. Blood Pressure Measurement Before and After Intervention -- 10. Novel Drugs in the Treatment of Hypertension -- 11. Adherence to Medications in Uncontrolled Hypertension -- 12. Pathophysiology of Renal Sympathetic Denervation -- 13. Renal Denervation: A Historical Perspective -- 14. Procedural Aspects of Renal Sympathetic Denervation -- 15. Safety of Renal Denervation -- 16. Efficacy of Renal Denervation on Blood Pressure Reduction -- 17. Effects of Renal Denervation on Intermediate End Points -- 18. Renal Denervation for Chronic Heart Failure -- 19. Effects of Renal Denervation on Chronic Kidney Disease -- 20. Effects of Renal Denervation on Sympathetic Nervous System Activity -- 21. Alternative Methods for Renal Denervation -- 22. Carotid Baroreceptor Stimulation -- 23. Central Iliac Arteriovenous Anastomosis for Hypertension.
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e-Book
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Online
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Psychoanalysis and Neuroscience

https://libcat.nshealth.ca/en/permalink/provcat30327
edited by Mauro Mancia. --Milan: Springer-Verlag Italia , c2006.
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Author
Mancia, Mauro
Responsibility
edited by Mauro Mancia
Place of Publication
Milan
Publisher
Springer-Verlag Italia
Date of Publication
c2006
ISBN
9788847005501
Subjects (MeSH)
Emotions - physiology
Memory - physiology
Neurophysiology - methods
Neuropsychology - methods
Psychoanalysis - methods
Subjects (LCSH)
Psychiatry
Neurosciences
Format
e-Book
Location
Online
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Resistant Hypertension : Epidemiology, Pathophysiology, Diagnosis and Treatment

https://libcat.nshealth.ca/en/permalink/provcat40842
Giuseppe Mancia, editor. --Milan: Springer , c2013.
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A growing number of people suffer from so-called resistant hypertension, that is to say, high blood pressure that does not respond to treatment. This disorder is of great current interest and importance for public health, being a common clinical problem faced by both primary care clinicians and specialists. Furthermore, as older age and obesity are among the strongest risk factors for uncontrolled hypertension, the incidence of resistant hypertension will likely increase as the population becom…
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Other Authors
Mancia, Giuseppe
Responsibility
Giuseppe Mancia, editor
Place of Publication
Milan
Publisher
Springer
Date of Publication
c2013
Physical Description
1 online resource (viii, 195 p. : ill.)
ISBN
9788847054158
9788847054141 (print ed.)
Subjects (MeSH)
Antihypertensive Agents
Drug Resistance
Hypertension - diagnosis
Hypertension - physiopathology
Hypertension - therapy
Abstract
A growing number of people suffer from so-called resistant hypertension, that is to say, high blood pressure that does not respond to treatment. This disorder is of great current interest and importance for public health, being a common clinical problem faced by both primary care clinicians and specialists. Furthermore, as older age and obesity are among the strongest risk factors for uncontrolled hypertension, the incidence of resistant hypertension will likely increase as the population becomes more elderly and heavier. While the prognosis of resistant hypertension is unknown, cardiovascular risk is undoubtedly increased since patients often have a history of long-standing, severe hypertension complicated by multiple other cardiovascular risk factors. This volume, compiled by a panel of world-renowned experts, offers a comprehensive exploration of resistant hypertension, covering epidemiology, complex diagnostic aspects, and the therapeutic options currently available, with due attention to overall treatment strategies. New therapeutic agents and procedures, such as renal denervation and baroreceptor stimulation, are also described. In addition, the book addresses the economic aspects of resistant hypertension and the role of the different professional figures, from GPs to hypertension specialists, in dealing with it.
Contents
1. Resistant Hypertension: Definition, Prevalence and Cardiovascular Risk -- Part I. Pathophysiology -- 2. Resistant Hypertension: Neurohumoral Aspects -- 3. Metabolic Alterations -- 4. Cardiac and Vascular Alterations in Resistant Hypertension -- 5. The Pathophysiology of the Kidney in Resistant Hypertension -- Part II. Diagnostic Aspects -- 6. False vs. True Resistant Hypertension -- 7. Causes of Resistant Hypertension -- 8. 24-hour Ambulatory BP Monitoring and Home BP Measurements in Resistant Hypertension -- 9. Factors Predicting Blood Pressure Response to Treatment -- 10. Treatment of Resistant Hypertension. Which Additional Antihypertensive Drugs? -- 11. The Role of Renal Denervation -- 12. The Role of Carotid Baroreceptor Stimulation -- 13. Pathophysiology: Metabolic Alterations and Risk Factors -- 14. Follow-up of Patients with Resistant Hypertension -- 15. Resistant Hypertension: Cost-Benefit Considerations -- 16. Involvement of Health Professionals: From the General Practitioner to the Hypertension Specialist and the Hypertension Center.
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e-Book
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Special issues in hypertension

https://libcat.nshealth.ca/en/permalink/provcat31256
Adel E. Berbari, Giuseppe Mancia, editors. --Milan: Springer , c2012.
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This volume is a cutting-edge review of the latest findings on key scientific and clinical issues in hypertension, with an integration of different new specific topics into the general knowledge of how to understand the pathophysiology and correctly diagnose and treat this chronic condition, which still represents the first cause of death in the world. Among the topics included in the book the reader will find some forms of hypertension which are frequently encountered in clinical practice and …
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Other Authors
Berbari, Adel E
Mancia, Giuseppe
Responsibility
Adel E. Berbari, Giuseppe Mancia, editors
Place of Publication
Milan
Publisher
Springer
Date of Publication
c2012
Physical Description
1 online resource (x, 483 p. : 69 ill.)
ISBN
9788847026018
Subjects (MeSH)
Hypertension
Subjects (LCSH)
Angiography
Cardiology
Abstract
This volume is a cutting-edge review of the latest findings on key scientific and clinical issues in hypertension, with an integration of different new specific topics into the general knowledge of how to understand the pathophysiology and correctly diagnose and treat this chronic condition, which still represents the first cause of death in the world. Among the topics included in the book the reader will find some forms of hypertension which are frequently encountered in clinical practice and on which new important evidence is available, such as high-normal blood pressure (also termed pre-hypertension), white-coat and masked hypertension, and high blood pressure in the elderly and the very elderly. These emerging aspects are discussed in detail, along with chapters on issues of great current interest, such as the way to assess and how to treat asymptomatic organ damage, emerging cardiovascular risk factors such as short and long-term blood pressure variability, cognitive impairment and dementia. The book also deals with the changing concepts in the management of hypertension and antihypertensive pharmacotherapy, and addresses specific topics which are rarely discussed in clinical medicine volumes, including hypertension in post-menopausal women, hormonal replacement therapy, inflammatory disorders, sexual dysfunction with treatment, and the effect of Ramadan fasting on blood pressure. This ready to hand but encompassing volume proves to be a comprehensive updating tool to professionals and clinical practitioners managing patients with hypertension.
Contents
1. Prehypertension: Definition, clinical significance and therapeutic approaches: to treat or not to treat -- 2. Clinical significance and treatment requirement in white coat and masked hypertension -- 3. Resistant hypertension: epidemiologic and evolving therapeutic aspects -- 4. Primary aldosteronism: rare or common condition -- 5. Hypertension in the very elderly: special features, therapeutic approaches and problems -- 6. Clinical relevance of circadian rhythm and nocturnal dip -- 7. Morning BP surge in treated and untreated hypertensive patients: clinical relevance, prognostic significance and therapeutic approaches -- 8. Short-term and long-term BP variability -- 9. Home BP in hypertension -- 10. Obstructive sleep apnea -- 11. Hypertension, obesity and the metabolic syndrome -- 12.Salt, hypertension and cardiovascular disease -- 13. Optic fundus and retinal circulation: new technology for an old examination -- 14. Arterial stiffness as an early marker of organ damage -- 15. Central blood pressure: definition, clinical significance and therapeutic approaches -- 16. Assessment of total cardiovascular risk in Hypertension: the role of subclinical organ damage -- 17. Microcirculation in hypertension -- 18. Smoking, nicotine and BP -- 19. Inflammatory markers and other risk factors in Hypertension -- 20. Benefits: pleiotropic versus BP dependent mechanisms -- 21. Threshold and target BP values for treatment: an evolving concept -- 22. Polypill concept -- 23. J-curve phenomenon: Does it exist? -- 24. Residual risk in treated hypertension -- 25. Poor BP control in the hypertensive population: which factors are involved -- 26. Ramadan fasting and BP control -- 27. Hormone replacement therapy in postmenopausal hypertensive women -- 28. Treating pain and inflammation in hypertension -- 29. Sexual function in untreated and treated hypertension -- 30. Cognitive function and dementia in hypertension. Epidemiologic and therapeutic aspects -- 31 Is hypertension preventable? -- 32. Atrial fibrillation. Modern epidemiologic and therapeutic aspects -- 33. Genetics and hypertension. Which information for clinical practice -- 34. Dual blockade of RAAS: benefits versus adverse Outcome -- 35. Long-term effects of RAAS blockade on renal function.
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e-Book
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White coat hypertension : an unresolved diagnostic and therapeutic problem

https://libcat.nshealth.ca/en/permalink/provcat34067
Giuseppe Mancia, Guido Grassi, Gianfranco Parati, Alberto Zanchetti. --Cham, Switzerland: Springer , c2015.
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Author
Mancia, Giuseppe
Other Authors
Grassi, Guido
Parati, G
Zanchetti, Alberto
Responsibility
Giuseppe Mancia, Guido Grassi, Gianfranco Parati, Alberto Zanchetti
Place of Publication
Cham, Switzerland
Publisher
Springer
Date of Publication
c2015
Physical Description
1 online resource (viii, 147 pages)
ISBN
9783319074108 (electronic bk.)
9783319074092
Subjects (MeSH)
White Coat Hypertension
Subjects (LCSH)
Fear of doctors
Physician and patient
Contents
1. White Coat Hypertension: Definition, Terminology and Prevalence -- 2. Diagnostic Approach to White Coat Effect and White Coat Hypertension -- 3. Neurogenic and Non-neurogenic Mechanisms of White-Coat Hypertension -- 4. Predictive Factors for White-Coat Hypertension -- 5. White Coat Hypertension and Target Organ Damage -- 6. White Coat Hypertension, Metabolic Risk Factors and Cardiovascular Risk Profile -- 7. White Coat Hypertension and Cardiovascular Morbidity and Mortality -- 8. White Coat Hypertension: To Treat or Not to Treat -- 9. White Coat Hypertension: The History of the Irresistible, Resistible Ascent of a Misnomer.
Format
e-Book
Location
Online
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