Benign Hematologic Disorders in Children : A Clinical Guide
https://libcat.nshealth.ca/en/permalink/provcat46337
Deepak M. Kamat, Melissa Frei-Jones, editors.
--Cham:
Springer
, c2021.
- Available Online
- View e-Book
- Access
- NEW Springer 2021
- Location
- Online
This book provides a comprehensive overview of benign hematologic disorders in children. Divided into nine sections, the text reviews common hematologic disorders or conditions that affect children, while providing state-of-the-art information on pathophysiology, diagnosis, treatment, and management strategies. The text begins with a section on hematopoiesis, and the next section covers red blood cell disorders. The following sections provide overviews of platelet disorders, white blood cell di…
- Available Online
- View e-Book
- Other Authors
- Kamat, Deepak M.
- Frei-Jones, Melissa
- Responsibility
- Deepak M. Kamat, Melissa Frei-Jones, editors
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2021
- Physical Description
- 1 online resource (xiii, 512 p.)
- ISBN
- 9783030499808
- 9783030499792 (Print ed.)
- 9783030499815 (Print ed.)
- 9783030499822 (Print ed.)
- Subjects (MeSH)
- Child
- Hematologic Diseases
- Specialty
- Hematology
- Pediatrics
- Abstract
- This book provides a comprehensive overview of benign hematologic disorders in children. Divided into nine sections, the text reviews common hematologic disorders or conditions that affect children, while providing state-of-the-art information on pathophysiology, diagnosis, treatment, and management strategies. The text begins with a section on hematopoiesis, and the next section covers red blood cell disorders. The following sections provide overviews of platelet disorders, white blood cell disorders, and coagulation disorders. The sixth and seventh sections discuss neonatal hematology and bone marrow failure syndrome. The eighth section reviews supportive care, while the final section covers miscellaneous subjects including pediatric vascular anomalies and complement dysregulation syndromes. Written by experts in the field, Benign Hematologic Disorders in Children: A Clinical Guide is a valuable resource for clinicians and practitioners who treat children afflicted with these disorders.
- Contents
- Part I. Origin of Blood Cells -- Hematopoiesis -- Part II. Red Blood Cell Disorders -- Nutritional Anemias: Iron Deficiency and Megaloblastic Anemia -- Lead Poisoning -- Immune and Non-Immune Hemolytic Anemia -- Sickle Cell Disease -- Thalassemia -- Disorders of RBC Metabolism -- Red blood cell membrane defects -- Part III. Platelet disorders -- Immune Thrombocytopenia -- Inherited and Congenital Thrombocytopenia -- Platelet Disorders -- Thrombocytosis in Children -- Part IV. WBC disorders -- Neutropenia -- Granulocytosis -- Disorders of Granulocyte Functions -- Part V. Coagulation Disorders -- Von Willebrand Disease -- Hemophilia -- Acquired Disorders of Coagulation in Neonates and Children -- Thromboembolism -- Heavy Menstrual Bleeding and Bleeding Disorders in Adolescents: A Primer for the Primary Care Physician -- Part VI. Neonatal Hematology -- Newborn Screening for Hemoglobinopathies -- Neonatal Immune Hemolytic Anemia -- Neonatal Hemostasis Disorders of Bilirubin Metabolism -- Part VII. Bone Marrow Failure Syndrome -- Failure of Erythrocyte Production -- Inherited Bone Marrow Failure Syndromes -- What Pediatricians Need to Know about Acquired Aplastic Anemia -- Part VIII. Supportive Care -- Immunizations in the Child with Sickle Cell Disease -- Transfusion Medicine for Pediatrics -- Management of infections in neutropenic patients -- Part IX. Miscellaneous -- Pediatric Vascular Anomalies: Opportunities in Primary Care -- Complement Dysregulation Syndromes in Children and Adolescents.
- Access
- NEW Springer 2021
- Format
- e-Book
- Location
- Online
Cancer Immunology : Bench to Bedside Immunotherapy of Cancers
https://libcat.nshealth.ca/en/permalink/provcat46359
Nima Rezaei, editor.
(Second edition)
--Cham:
Springer
, c2021.
- Available Online
- View e-Book
- Access
- NEW Springer 2021
- Location
- Online
This translational, clinically oriented book describes in detail novel approaches to cancer immunotherapy, current strategies to target tumor immunosuppression, and prognostic biomarkers for personalized cancer treatments. Since the first, very successful edition of the book was published in 2015, the original chapters have been significantly updated and entirely new chapters are included on, for example, cancer immunoprevention, aptamer-mediated cancer gene therapy, haploidentical bone marrow …
- Available Online
- View e-Book
- Other Authors
- Rezaei, Nima
- Responsibility
- Nima Rezaei, editor
- Edition
- Second edition
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2021
- Physical Description
- 1 online resource (xl, 658 p.) : 53 illus., 46 illus. in color
- ISBN
- 9783030502874
- 9783030502867 (Print ed.)
- 9783030502881 (Print ed.)
- 9783030502898 (Print ed.)
- Subjects (MeSH)
- Immunotherapy - methods
- Neoplasms - immunology
- Neoplasms - therapy
- Abstract
- This translational, clinically oriented book describes in detail novel approaches to cancer immunotherapy, current strategies to target tumor immunosuppression, and prognostic biomarkers for personalized cancer treatments. Since the first, very successful edition of the book was published in 2015, the original chapters have been significantly updated and entirely new chapters are included on, for example, cancer immunoprevention, aptamer-mediated cancer gene therapy, haploidentical bone marrow transplantation for pediatric malignancies, and nanoimmunotherapy. The book is published as part of the three-volume Springer series Cancer Immunology, which aims to provide an up-to-date, clinically relevant review of cancer immunology and immunotherapy. Other volumes in the series address the translational medicine context and cancer immunotherapy for organ-specific tumors. Cancer Immunology: Bench to Bedside Immunotherapy of Cancers will be of special value to clinical immunologists, hematologists, and oncologists.
- Contents
- Frontiers in Cancer Immunotherapy -- Novel Strategy of Cancer Immunotherapy: Spiraling Up -- Novel Prognostic Biomarkers for Personalized Cancer Treatments -- Tumor Antigen and Epitope Identification for Pre-Clinical and Clinical Evaluation -- Strategies to Target Tumor Immunesuppression -- Immune Modulation of Drugs in Prevention and Treatment of Cancers -- Overcoming Immune Tolerance With Immune Checkpoint Blockade -- Gene therapy and Virus-Based Cancer Vaccines -- Cancer Stem Cells: Biology and Potential therapeutic Applications -- Hematopoietic Stem Cell Transplantation and Lymphodepletion in Treatment of Cancers -- Combination of Chemotherapy and Cytokine Therapy in Treatment of Cancers -- T Cell Immunotherapy: From Synthetic Biology to Clinical Practice -- Role of Gamma-Delta T Lymphocytes in Cancer Immunosurveillance and Immunotherapy -- Adoptive T Cell therapy: Optimizing Chemokine Receptor-Mediated Homing of T Cells in Cancer Immunotherapy -- Cellular therapy of Cancer With B Effector Cells -- Monoclonal Antibodies for Treatment of Cancers -- Pattern Recognition Receptors in Cancers and Immunotherapy by Triggering or Targeting of Toll Like Receptors Pathway -- Recent Advances in the Use of NK Cells Against Cancer -- Dendritic Cell Vaccines for Cancer Therapy: Fundamentals and Clinical Trials -- Tumor Associated Macrophages and iNOS in Cancer Immunotherapy -- Photodynamic therapy and Anti-Tumor Immune Response -- Polarization of Tumor Milieu: Therapeutic Implications -- Immunotherapies Targeting 5T4 Oncofoetal Glycoprotein -- Immune Monitoring During Clinical Development of Anti-CTLA-4 Antibody Therapy -- PD-1 Blockade in Cancer Therapy -- New Advances in Radioimmunotherapy for the Treatment of Cancers -- Psychoneuroendocrinoimmunotherapy of Cancers -- Ethical Considerations in Cancer Immunotherapy.
- Access
- NEW Springer 2021
- Format
- e-Book
- Location
- Online
The Illustrative Book of Cartilage Repair
https://libcat.nshealth.ca/en/permalink/provcat46374
Deepak Rajkumar Goyal, editor.
--Cham:
Springer
, c2021.
- Available Online
- View e-Book
- Access
- NEW Springer 2021
- Location
- Online
This book employs a wealth of high-quality illustrations to provide the reader with a detailed understanding of the anatomy and the histology of the cartilage, the etiology and the classification of the cartilage lesions, and the numerous techniques employed for cartilage repair. Detailed attention is devoted to healthy cartilage, to each stage in the degenerative process, and to the response of the cartilage to the treatment. Imaging of the damaged and the repaired cartilage, as well as the in…
- Available Online
- View e-Book
- Other Authors
- Goyal, Deepak Rajkumar
- Responsibility
- Deepak Rajkumar Goyal, editor
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2021
- Physical Description
- 1 online resource (xvii, 270 p.) : 290 illus., 259 illus. in color
- ISBN
- 9783030471545
- 9783030471538 (Print ed.)
- 9783030471552 (Print ed.)
- 9783030471569 (Print ed.)
- Subjects (MeSH)
- Cartilage Diseases - surgery
- Cartilage, Articular - surgery
- Specialty
- Orthopedic Procedures
- Abstract
- This book employs a wealth of high-quality illustrations to provide the reader with a detailed understanding of the anatomy and the histology of the cartilage, the etiology and the classification of the cartilage lesions, and the numerous techniques employed for cartilage repair. Detailed attention is devoted to healthy cartilage, to each stage in the degenerative process, and to the response of the cartilage to the treatment. Imaging of the damaged and the repaired cartilage, as well as the information on the biomechanics are provided in great detail. The chapters on the techniques cover a wide range of approaches: marrow stimulation techniques, osteochondral cylinder transfer techniques, first, second and third generation autologous chondrocyte implantation techniques, allografts, cell-based therapies, orthobiologic approaches, and the role of 3D printing. The chapters closes with a consideration of the success of rehabilitation devices and the long-term results of cartilage repair.The book will be invaluable for all general orthopaedic and arthroscopic surgeons seeking a deeper knowledge of cartilage science and will help to dispel the confusion that still surrounds the reparative treatment. The authors are recognized experts in the fields of cartilage histology, assessment, classification, and repair.
- Contents
- 1. The Science of Illustrated Cartilage Repair and Its Rationale -- 2. The Illustrative Anatomy and the Histology of the Healthy Hyaline Cartilage -- 3. The Illustrative Anatomy and the Histology of the Degenerative Hyaline Cartilage -- 4. The Illustrative Role of the Subchondral Bone and the Overlying Cartilage -- 5. The Illustrative Biomechanics of a Chondral Injury -- 6. The Classifications of the Chondral Lesions -- 7. The Illustrative Magnetic Resonance Imaging of the Chondral and the Osteochondral Lesions -- 8. The Illustrative Role of Cells in Cartilage Repair -- 9. The Illustrative Chondral and Osteochondral Scaffolds in Cartilage Repair -- 10. The Illustrative Marrow Stimulation Techniques for Cartilage Repair: The Microfracture Technique -- 11. The Illustrative Osteochondral Cylinder Transfer Techniques for Cartilage Repair: The Mosaicplasty Technique -- 12. The Illustrative Osteochondral Cylinder Transfer Techniques for Cartilage Repair: The OATS Technique -- 13. The Illustrative First and Second Generation Autologous Chondrocyte Implantation (ACI) for Cartilage Repair -- 14. The Illustrative Membrane Based Autologous Chondrocyte Implantation for Cartilage Repair -- 15. The Illustrative Third Generation Autologous Chondrocyte Implantation for Cartilage Repair: The Gel Based ACI Technique -- 16. The Illustrative Single-Stage Cartilage Repair Technique with Chitosan-Based Bioscaffold (BST-CarGel) -- 17. The Illustrative Multilayer Scaffolds for the Single-Stage Cartilage Repair in the Osteochondral Lesions -- 18. The Illustrative Bone Marrow Aspirate Concentrate and Hyaluronan-Based Scaffold Technique for Single-Stage Cartilage Repair -- 19. The Illustrative Overlay Autologous Chondrocyte Implantation (Overlay ACI) Technique for Repair of the Extra-Large Osteochondral Defects -- 20. The Illustrative Osteochondral Allograft-Based Cartilage Repair -- 21. The Illustrative 3D Bioprinting in Cartilage Repair -- 22. The Illustrative Magnetic Resonance Image (MRI) Assessment of Cartilage Repair.
- Access
- NEW Springer 2021
- Format
- e-Book
- Publication Type
- Atlas
- Location
- Online
Stem Cell Therapy for Vascular Diseases : State of the Evidence and Clinical Applications
https://libcat.nshealth.ca/en/permalink/provcat46407
Tulio Pinho Navarro, Lara Lellis Navarro Minchillo Lopes, Alan Dardik, editors.
--Cham:
Springer
, c2021.
- Available Online
- View e-Book
- Access
- NEW Springer 2021
- Location
- Online
Vascular diseases are the leading cause of death worldwide. Distinguished clinical and surgical approaches have attempted to overcome its morbidity and mortality; still 17.9 million people die every year due to vascular affections. Stem cell therapy has emerged as a promising therapeutic strategy. Stem cells synthesize and secrete cytokines that promote cell recruitment, immunomodulation, extracellular matrix remodeling, angiogenesis, and neuroregeneration, all of which promote regeneration. Be…
- Available Online
- View e-Book
- Responsibility
- Tulio Pinho Navarro, Lara Lellis Navarro Minchillo Lopes, Alan Dardik, editors
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2021
- Physical Description
- 1 online resource (xii, 425 p.) : 46 illus., 38 illus. in color
- ISBN
- 9783030569549
- 9783030569532 (Print ed.)
- 9783030569556 (Print ed.)
- 9783030569563 (Print ed.)
- Subjects (MeSH)
- Regenerative Medicine - methods
- Stem Cell Transplantation - methods
- Vascular Diseases - therapy
- Specialty
- Cardiology
- Hematology
- Regenerative Medicine
- Abstract
- Vascular diseases are the leading cause of death worldwide. Distinguished clinical and surgical approaches have attempted to overcome its morbidity and mortality; still 17.9 million people die every year due to vascular affections. Stem cell therapy has emerged as a promising therapeutic strategy. Stem cells synthesize and secrete cytokines that promote cell recruitment, immunomodulation, extracellular matrix remodeling, angiogenesis, and neuroregeneration, all of which promote regeneration. Besides that, stem cells are also capable of differentiating in various cell types, being employed in tissue engineering. Preclinical and clinical investigations have reported efficacy of stem cell therapy for various vascular diseases. Even though results are encouraging, the studies demonstrate variation in stem cell type and origin, route and protocol for administration, and concomitant use of other treatment strategies, impairing easy interpretation of results and clinical application. The purpose of this book is to compile and comprise the current state of the evidence regarding stem cell therapy for each vascular disease, elucidating possible clinical applications. More than an objective guide for readers on the use of this novel treatment strategy, this publication will advocate for stem cell therapy use and development and will be of significant interest to physicians in a wide range of disciplines as well as researchers.
- Contents
- 1. Introduction to Stem Cell Therapy and its Application in Vascular Diseases -- 2. Types And Origin of Stem Cells -- 3. Stem Cell Delivery Techniques for Stroke and Peripheral Artery Disease -- 4. The Ethical Challenges of Stem Cell Therapy in Vascular Disorders -- 5. Bone Marrow-Derived Cells: from the Laboratory to the Clinic -- 6. Angiogenesis: Perspectives From Therapeutic Angiogenesis -- 7. Stem Cell Therapy for Diabetic Foot Ulcers -- 8. Venous Foot and Leg Ulcers -- 9. Induced Pluripotent Stem Cell-Derived Vascular Smooth Muscle Cells for Vascular Regeneration -- 10. Mesenchymal Stem Cell and Hematopoietic Stem Cell Transplantation for Vasculitis -- 11. Mesenchymal Stem Cell and Endothelial Progenitor Cell Transplantation for Buerger's Disease -- 12. Changing the Course of Peripheral Arterial Disease Using Adult Stem Progenitor Cells -- 13. Stem Cell Delivery for the Treatment of Arteriovenous Fistula Failure -- 14. Stem Cell Therapy to Improve Acute Myocardial Infarction Remodeling -- 15. Stem Cell Therapy for Stroke -- 16. Use of Stem Cells in the Treatment of Erectile Dysfunction -- 17. Stem Cell Therapy for Ophthalmic Vascular Disease -- 18. Stem Cell Therapy Delivery in Liver Disease -- 19. Stem Cell Therapy for Lymphedema.
- Access
- NEW Springer 2021
- Format
- e-Book
- Location
- Online
Lower Extremity Joint Preservation : Techniques for Treating the Hip, Knee, and Ankle
https://libcat.nshealth.ca/en/permalink/provcat46530
Mats Brittberg, Konrad Slynarski, editors.
--Cham:
Springer
, c2021.
- Available Online
- View e-Book
- Access
- NEW Springer 2021
- Location
- Online
This book describes and discusses the available joint preservation techniques for maintaining the stability homeostasis of the lower extremity joints – specifically the hip, knee, and ankle – following injury. Readers will find detailed coverage of anatomy, pathology, techniques for repair, restoration, and regeneration, and rehabilitation strategies. Joint preservation is an emerging field in Orthopaedics that represents a response to the limitations of joint replacement technology. Using the …
- Available Online
- View e-Book
- Other Authors
- Brittberg, Mats
- Slynarski, Konrad
- Responsibility
- Mats Brittberg, Konrad Slynarski, editors
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2021
- Physical Description
- 1 online resource (xi, 345 p.) : 180 illus., 153 illus. in color
- ISBN
- 9783030573829
- 9783030573812 (Print ed.)
- 9783030573836 (Print ed.)
- 9783030573843 (Print ed.)
- Subjects (MeSH)
- Ankle Joint - surgery
- Hip Joint - surgery
- Knee Joint - surgery
- Orthopedic Procedures
- Specialty
- Orthopedics
- Abstract
- This book describes and discusses the available joint preservation techniques for maintaining the stability homeostasis of the lower extremity joints – specifically the hip, knee, and ankle – following injury. Readers will find detailed coverage of anatomy, pathology, techniques for repair, restoration, and regeneration, and rehabilitation strategies. Joint preservation is an emerging field in Orthopaedics that represents a response to the limitations of joint replacement technology. Using the techniques now available, surgeons can try to prevent or delay the onset of osteoarthritis or other degenerative conditions affecting the joints, particularly in young patients. Furthermore, modern tissue engineering offers the potential for whole-joint resurfacing, thereby achieving complete restoration. Optimal implementation of these techniques depends upon further refinement of methods and continuing improvements in knowledge of biomechanics, biology, and anatomy. Against this background, the present book is an ideal guide to the latest treatment modalities that will appeal to all who wish to learn more about indications, goals, procedures, and expected outcomes.
- Contents
- Part I. Hip -- 1. Comprehensive Hip Preservation: Correction of Adult Hip Dysplasia and Repair of High-Grade Cartilage Injury -- 2. Anatomy of the Hip Joint Preservation Point of View -- 3. Anatomy, Surgical Management, and Postoperative Outcomes of Acetabular Labral Tears -- Part II. Knee -- 4. Bone Marrow Stimulation Techniques for Cartilage Repair -- 5. One-Step Cell-Based Cartilage Repair in the Knee Using Hyaluronic Acid-Based Scaffold Embedded with Mesenchymal Stem Cells Sourced from Bone Marrow Aspirate Concentrate (HA-BMAC) -- 6 Chondrocyte Implantation -- 7. Joint Preservation with Stem Cells -- 8. Cartilage Pathology and Repair: Fresh Allografts -- 9. Synthetic and Mini-metal Implants in the Knee -- 10. Knee Joint Preservation Rehabilitation -- 11. Meniscus Anatomy -- 12. Current Concepts in Meniscus Pathology and Repair -- 13. Meniscus Allograft Transplantation -- 14. Biomaterials in Meniscus Repair -- 15. Internal Bracing of the Anterior Cruciate Ligament and Posterior Cruciate Ligament with Suture Tape Augmentation -- 16. Anterior Cruciate Ligament Reconstruction -- 17. Preservation of the Anterior Cruciate Ligament: Arthroscopic Primary Repair of Proximal Tears -- 18. The Anterolateral Ligament -- 19. ACL and Cartilage Lesions -- 20. Repair and Reconstruction of the Medical Collateral Ligament -- 21. The Posterolateral Ligament Complex of the Knee -- 22. Patellar Instability -- 23. Arthroscopic Trochleoplasty -- 24. Open Trochleoplasty -- 25. Patellofemoral Osteotomies - 26. Unloading Osteotomies Around the Knee -- 27. Joint Preservation by Articular Joint Unloading -- 28. Overload Assessment and Prevention in Knee Joint Malalignment Using Gait Analysis -- 29. Return to Sports After Knee Surgery for Intraarticular Pathology -- Part III. Ankle -- 30. Ankle Joint Cartilage Pathology and Repair -- 31. Ankle Rehabilitation.
- Access
- NEW Springer 2021
- Format
- e-Book
- Location
- Online
Blood and Marrow Transplant Handbook
https://libcat.nshealth.ca/en/permalink/provcat46597
Richard T. Maziarz, Susan Schubach Slater.
(Third edition)
Springer
, 2021.
- Available Online
- View e-Book
- Location
- Online
- Available Online
- View e-Book
- Responsibility
- Richard T. Maziarz, Susan Schubach Slater
- Edition
- Third edition
- Publisher
- Springer
- Date of Publication
- 2021
- Physical Description
- 1 online resource (xx, 1006 pages) : illustrations
- ISBN
- 9783030536268
- Specialty
- Hematology
- Transplantation
- Format
- e-Book
- Location
- Online
Biology and Treatment of Leukemia and Bone Marrow Neoplasms
https://libcat.nshealth.ca/en/permalink/provcat47145
Vinod Pullarkat, Guido Marcucci.
Springer
, 2021.
- Available Online
- View e-Book
- Location
- Online
- Available Online
- View e-Book
- Responsibility
- Vinod Pullarkat, Guido Marcucci
- Publisher
- Springer
- Date of Publication
- 2021
- Physical Description
- 1 online resource (viii, 196 pages) : illustrations
- Series Vol.
- 181
- Series Title
- Cancer treatment and research
- ISBN
- 9783030783112
- Specialty
- Hematology
- Medical Oncology
- Format
- e-Book
- Location
- Online
COVID-19 vaccination and cancer FAQ
https://libcat.nshealth.ca/en/permalink/chpams37451
Nova Scotia Health Authority. Cancer Care Program.
Halifax, NS:
Nova Scotia Health Authority
, 2021.
- Pamphlet Number
- 4000
- Available Online
- View Pamphlet
As a person living with cancer, or a blood or bone marrow condition, you may have questions about COVID-19 vaccination. This pamphlet explains if the vaccine is safe for people with cancer, how well the vaccine works in people with cancer, when you should get the vaccine, and which vaccine you should get. Possible side effects are listed. Information on who to talk to if you still have questions about the vaccine, and what will happen after you get the vaccine is provided.
- Available Online
- View Pamphlet
- Corporate Author
- Nova Scotia Health Authority. Cancer Care Program
- Alternate Title
- Coronavirus vaccination and cancer FAQ
- COVID-19 vaccination and cancer frequently asked questions
- Place of Publication
- Halifax, NS
- Publisher
- Nova Scotia Health Authority
- Date of Publication
- 2021
- Format
- Pamphlet
- Language
- English
- Physical Description
- 1 electronic document ([2] p.) : digital, PDF file
- Subjects (MeSH)
- COVID-19 Vaccines
- Neoplasms - complications
- Subjects (LCSH)
- COVID-19 (Disease)--Vaccination
- Cancer--Complications
- Abstract
- As a person living with cancer, or a blood or bone marrow condition, you may have questions about COVID-19 vaccination. This pamphlet explains if the vaccine is safe for people with cancer, how well the vaccine works in people with cancer, when you should get the vaccine, and which vaccine you should get. Possible side effects are listed. Information on who to talk to if you still have questions about the vaccine, and what will happen after you get the vaccine is provided.
- Responsibility
- Prepared by: Nova Scotia Health Cancer Care Program
- Pamphlet Number
- 4000
Hematopathology
https://libcat.nshealth.ca/en/permalink/provcat44966
Thierry J. Molina, editor.
--Cham:
Springer
, c2020.
- Available Online
- View e-Book
- Location
- Online
This book covers the complete filed of hematopathology - from Acute Leukaemia to the WHO classification. The alphabetically arranged entries, each of which provides a detailed description of a specific pathological disease pattern, allow readers to quickly and easily find the information they need.
- Available Online
- View e-Book
- Other Authors
- Molina, Thierry J.
- Responsibility
- Thierry J. Molina, editor
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2020
- Physical Description
- 1 online resource (xxii, 505 pages) : illustrations
- Series Title
- Encyclopedia of pathology
- Springer reference
- ISBN
- 9783319953090
- 9783319953083 (Print ed.)
- ISSN
- 2366-6269
- Subjects (MeSH)
- Hematologic Diseases - pathology
- Specialty
- Hematology
- Pathology
- Abstract
- This book covers the complete filed of hematopathology - from Acute Leukaemia to the WHO classification. The alphabetically arranged entries, each of which provides a detailed description of a specific pathological disease pattern, allow readers to quickly and easily find the information they need.
- Contents
- Acute Leukaemia, Ambiguous Lineage -- Acute Leukaemia, Myeloid -- Adult T-Cell Leukaemia/Lymphoma -- Anaemia -- Anaplastic Large Cell Lymphoma -- Angioimmunoblastic T-cell Lymphoma -- Aplastic Anemia -- Autoimmuni Haemolytic Anemia -- B-cell chronic lymphocytic leukaemia/small lymphocytic lymphoma -- B-Cell Prolymphocytic Leukemia -- Blastic Plasmacytoid Dendritic Neoplasm -- Blood -- Bone Marrow -- Burkitt Lymphoma -- Castleman Disease -- Cat Scratch Lymphadenitis -- Chronic Myelogenous Leukemia -- Chronic Myelomonocytic Leukemia -- Dendritic Cell Neoplasms -- Dermatopathic Lymhpadenitis -- Diffuse Large B-cell Lymphoma -- Enteropathy-Associated T-Cell Lymphoma -- Eosinophilia -- Erythrocytosis -- Essential Thrombocythemia -- Extranodal Marginal Zone Lymphoma -- Extranodal NK/T Cell Lymphoma, Nasal Type -- Follicular Lymphoid Hyperplasia -- Follicular Lymphoma -- Granulomatous Lymphadenitis -- Hairy Cell Leukaemia -- Heavy Chain Diseases -- Hemophagocytic Syndrome -- Hepatosplenic T-Cell Lymphoma -- HHV8-Associated Lymphoid Disorders -- Histiocytic Neoplasma -- HIV-Associated Lymphoid Disorders -- Hodgkin Lymphoma, Classical -- Hodgkin Lymphoma, Nodular Lymphocyte Predominant -- Idiopathic Thrombocytopenia Purpura -- Immunodeficiency-Associated Lymphoproliferative Disorders -- Inflammatory Pseudotumor -- Kikuchi-Fujimoto Lymphadenitis -- Kimura's Disease -- Langerhans Cell Histiocytosis -- Leukoerythroblastosis -- Littoral Cell Angioma -- Lymph Node -- Lymph Node Hamartoma -- Lymphadenitis -- Lymphoblastic Leukemia/Lymphoma -- Lymphoma Classification -- Lymphoplasmacytic Lymphoma -- Mantle Cell Lymphoma -- Mastocytosis -- Monoclonal Gammopathy of Uncertain Significance -- Mucosal Associated Lymphoid Tissue -- Myelodysplastic Syndromes -- Myeloid Sarcoma -- Myeloproliferative Neoplasms -- Neutropenia -- Neutrophilia -- Nodal Marginal Zone Lymphoma -- Pancytopenia -- Panniculits T-Cell Lymphoma -- Paroxysmal Nocturnal Hemoglobinuria -- Peliosis, Spleen -- Peripheral T-cell Lymphoma -- Plasma Cell Myeloma -- Plasmablastic Lymphoma -- Polycythemia Vera -- Primary Effusion Lymphoma -- Primary Mediastinal Large B-cell Lymphoma -- Primary Myelofibrosis -- Rosai-Dorfman-Destombes Disease -- Sea-Blue Histiocytosis -- Sinus Histiocytosis -- Spleen -- Spleen, Hamartoma -- Splenic Marginal Zone Lymphoma -- T-cell and NK Cell Mature Neoplasms -- T-cell Large Granular Lymphocytic Leukaemia -- T-cell/Histiocyte Rich Large B-Cell Lymphoma -- Therapy-Associated Myeloid Neoplasm -- Thrombocytopenia -- Thrombocytosis -- Toxoplasma Lymphadenitis -- WHO Classification.
- Format
- e-Book
- Publication Type
- Encyclopedia
- Location
- Online
Pediatric Autoimmunity and Transplantation : A Case-Based Collection with MCQs, Volume 3
https://libcat.nshealth.ca/en/permalink/provcat44981
Farzaneh Rahmani, Nima Rezaei, editors.
--Cham:
Springer
, c2020.
- Available Online
- View e-Book
- Location
- Online
This book is a collection of case-based questions, directed towards and meticulously selected to cover the most common and important aspects of pediatric autoimmune disorders. Autoimmune disorders of infancy and childhood, rheumatological disorders, dermatologic autoimmune disorders, autoinflammatory disorders, and clinical immunology in solid organ and hematopoietic stem cell transplantation are among the topics covered. Each chapter starts with a case description followed by a series of 5-6 m…
- Available Online
- View e-Book
- Other Authors
- Rahmani, Farzaneh
- Rezaei, Nima
- Responsibility
- Farzaneh Rahmani, Nima Rezaei, editors
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2020
- Physical Description
- 1 online resource (xxvii, 496 p.) : 72 illus., 67 illus. in color
- Series Vol.
- volume 3
- Series Title
- Pediatric immunology series
- ISBN
- 9783030262808
- 9783030262792 (Print ed.)
- 9783030262815 (Print ed.)
- 9783030262822 (Print ed.)
- Subjects (MeSH)
- Autoimmune Diseases
- Pediatrics
- Primary Immunodeficiency Diseases
- Specialty
- Allergy and Immunology
- Pediatrics
- Transplantation
- Abstract
- This book is a collection of case-based questions, directed towards and meticulously selected to cover the most common and important aspects of pediatric autoimmune disorders. Autoimmune disorders of infancy and childhood, rheumatological disorders, dermatologic autoimmune disorders, autoinflammatory disorders, and clinical immunology in solid organ and hematopoietic stem cell transplantation are among the topics covered. Each chapter starts with a case description followed by a series of 5-6 multiple choice questions (MCQ), presenting the flow from diagnosis to treatment in a step-wise, logical manner. The text guides the reader through the stream of real clinical practice from initial presentation, differential diagnosis, next best step, lab data, and definitive diagnosis to management and adverse effects of therapy. This MCQ format along with precise, yet detailed answer ensure a quick, reality learning to the reader. The book provides a quick guide and hands-on learning experience for pediatricians, hematologists, immunologists, transplant specialists, pulmonologists, as well as PhD and post-graduate researchers around the world.
- Contents
- Introduction to Autoimmunity, Secondary Immunodeficiency, and Transplantation-Fever and Cervical Lymphadenopathy-Prolonged Refractory High Fever-Pain in Both Knees-Challenging Pain in Knee and Ankle-Fever and Urticarial Rash-Knee Swelling and Rash-Malaise, Weight Loss and Intermittent Fever-Anemia, Microhematuria and Proteinuria-Fever, Anasarca and Arthralgia-Bradycardia in a Neonate-Annular Rash in a Neonate -- Itchy Facial Rash -- Muscle Weakness and Fever-Pruritic Erythematous Rashes on Face and Eyelids-Edema of Hands and Hypopigmented Lesions on Her Neck and Cheeks-Asymptomatic Atrophic Plaque on the Face-Morbiliform Rash and Fever-Recurrent Interstitial Keratitis and Audiovestibular Dysfunction-Breathlessness and Weight Loss -- Neck Swelling and Fever -- Puffy Face and Abdominal Distension -- Hematuria and Abdominal Mass-Pitting Edema and Desquamation-Fever and Cutaneous Nodules -- Neck Stiffness and Fever-Rash and Generalized Body Pains-Positive HIV and Violet Macular Rash-Weight Loss and Tuberculin Skin Test Anergy-Edema on Lower Limbs-Asthenia and Fatigue-Infections, Whitish Skin Papules and Subcutaneous Nodules-Recurrent Pneumonia and History of Transplantation-Painful Skin Nodules, Prolonged Fever and Cervical Lymphadenopathy-Malaise, Laryngitis and Fever-Acute Myeloid Leukemia Requiring Hematopoietic Stem Cell Transplantation -- Acute Myeloid Leukemia Requiring Hematopoietic Stem Cell Transplantation-Suspected Immunodeficiency -- Acute Myeloid Leukemia Requiring Hematopoietic Stem Cell Transplantation -- T-Lymphoblastic Lymphoma -- No Lymphocytes in an Infant -- DOCK8 Deficiency and No Matched Donor -- Diarrhea Post-HSCT -- Follow-Up of a Severe Combined Immunodeficiency, Who Received Bone-Marrow-Transplantation Four Decades Ago -- Nonalcoholic Steatohepatitis Referred for Liver Transplantation -- Acute Respiratory Distress during Stem Cell Infusion -- Acute Dyspnea after Platelet Transfusion-Requiring Immunization after Rescue Autologous HSCT-Fever and Abdominal Pain-Prolonged Fever, Rash and Mucosal Bleeding-Recurrent Infections, Diarrhea and Hypereosinophilia-Liver Transplantation Who Developed Pancytopenia Post-Transplantation-Kidney Transplant Candidate Showing Presence of Pre-Formed Donor-Specific-Antibodies Against a Prospective Living Donor -- Heart Transplant Candidate Who Required Extra-Corporal Membrane-Oxygenation (ECMO)-Acute Antibody-Mediated Rejection (AMR) Transplantation with Negative-Prospective Crossmatch Results-Kidney Transplantation in a Patient with End Stage Renal Disease (ESRD)-Secondary to Focal Segmental Glomerulosclerosis-Itchy Violaceous Plaques -- Photosensitivity and Bullous Lesions-Recurrent Bullous Lesions-Refractory Blisters and Erosions-Annular Blisters and Erosions-Vesicular Pruriginous Lesions -- Widespread Vesiculobullous Rash-Itchy Skin Rashes -- Blisters on Back and Upper Extremities-Itchy Blisters-Sudden Onset Grouped Blisters-Pruritic Blisters -- Widespread Depigmented and Hypopigmented Patches -- Whitish Patches -- Hyperpigmented Patches-Outbreaks of Erythematous and Necrotic Papules with Hemorrhagic Crusts -- Persistant, Annular Urticarial Plaque -- Yellow, Reddish Brown Skin Lesions -- Erythroderma -- Erythematous Scaly Plaques -- Multiple Circinate, Sterile, Flaccid, Relapsing Pustules -- Purpuric Macules and Oral Erosions -- Diffuse Skin Rash and Mucosal Lesions -- Painful Facial Ulceration -- Patchy Hair Loss -- Concerning Weight Loss Over Three Weeks -- Toddler with Bruising on Knees.
- Format
- e-Book
- Publication Type
- Case Reports
- Problems and Exercises
- Location
- Online
Measurements in Musculoskeletal Radiology
https://libcat.nshealth.ca/en/permalink/provcat45031
Victor N. Cassar-Pullicino, A. Mark Davies, editors.
--Berlin, Heidelberg:
Springer
, c2020.
- Available Online
- View e-Book
- Location
- Online
This practical and comprehensive book provides succinct and up-to-date information on the value of the various diagnostic radiological measurements made using all the imaging modalities currently employed in the management of a wide spectrum of musculoskeletal disorders, including developmental, paediatric, traumatic, degenerative, metabolic, tumoural and rheumatological conditions. The book has a unique design, with three distinct but dove-tailed sections. In the first section, the physico-che…
- Available Online
- View e-Book
- Other Authors
- Cassar-Pullicino, Victor N.
- Davies, A. Mark
- Responsibility
- Victor N. Cassar-Pullicino, A. Mark Davies, editors
- Place of Publication
- Berlin, Heidelberg
- Publisher
- Springer
- Date of Publication
- c2020
- Physical Description
- 1 online resource (xiv, 860 p.) : 570 illus., 506 illus. in color
- Series
- Medical Radiology. Diagnostic Imaging
- Series Title
- Medical radiology (Series)
- ISBN
- 9783540688976
- 9783540862765 (Print ed.)
- 9783540438533 (Print ed.)
- Subjects (MeSH)
- Anthropometry
- Body Weights and Measures
- Musculoskeletal System - anatomy & histology
- Musculoskeletal System - diagnostic imaging
- Musculoskeletal Diseases - diagnostic imaging
- Specialty
- Anatomy
- Diagnostic Imaging
- Abstract
- This practical and comprehensive book provides succinct and up-to-date information on the value of the various diagnostic radiological measurements made using all the imaging modalities currently employed in the management of a wide spectrum of musculoskeletal disorders, including developmental, paediatric, traumatic, degenerative, metabolic, tumoural and rheumatological conditions. The book has a unique design, with three distinct but dove-tailed sections. In the first section, the physico-chemical principles of the various imaging modalities used in measurements are explained, and the strengths and weaknesses of each modality are considered. The second section examines the application of the imaging modalities to obtain accurate measurements across all musculoskeletal anatomical sites. The final section focusses on the role of measurements in specific disease states, namely arthritis, metabolic bone disease, bone marrow disease and tumours of bone and soft tissue. All chapters are written by experts in the field, drawn from across Europe, and the book is lavishly illustrated throughout. It will provide an invaluable and easy-to-use reference on the performance and significance of imaging-based measurements at different anatomical sites and in different disease states.
- Contents
- Part I. Measurement Techniques -- 1. The Radiograph -- 2. Computed Tomography -- 3. Ultrasound -- 4. Magnetic Resonance Imaging -- 5. Computer-Assisted Quantification -- Part II. Measurements at Anatomical Sites -- 6. Cervical Spine -- 7. Thoracolumbar Spine -- 8. Shoulder -- 9. Elbow -- 10. Wrist/Hand -- 11. Pelvis/Hip Paediatric -- 12. Pelvis/Hip: Adult -- 13. Knee -- 14. Patellofemoral Joint -- 15. Foot and Ankle: Paediatric Measurements -- 16. The Adult Ankle and Foot -- 17. Long Bone Measurements -- Part III. Measurements in Disease States -- 18. Arthritis -- 19. Metabolic Bone Disease -- 20. Bone Marrow Disease -- 21. Bone and Soft Tissue Tumours.
- Format
- e-Book
- Location
- Online
Best Practices of Apheresis in Hematopoietic Cell Transplantation
https://libcat.nshealth.ca/en/permalink/provcat45065
Syed A. Abutalib, Anand Padmanabhan, Huy P. Pham, Nina Worel, editors.
--Cham:
Springer
, c2020.
- Available Online
- View e-Book
- Location
- Online
In this book, world-renowned experts in the field of hematopoietic cell transplantation examine a range of issues and controversies relating to apheresis, with the aim of identifying current trends and best practices. Readers will find up-to-date guidance on donor evaluation, CD34+ cell mobilization strategies, options and selection of apheresis device, anticoagulation techniques in apheresis, the role of prediction algorithms in determining procedure eligibility and length, and the prevention …
- Available Online
- View e-Book
- Other Authors
- Abutalib, Syed A.
- Padmanabhan, Anand
- Pham, Huy P.
- Worel, Nina
- Responsibility
- Syed A. Abutalib, Anand Padmanabhan, Huy P. Pham, Nina Worel, editors
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2020
- Physical Description
- 1 online resource (vi, 211 p.) : 33 illus., 29 illus. in color
- ISBN
- 9783319551319
- 9783319551302 (Print ed.)
- 9783319551326 (Print ed.)
- ISSN
- 2569-1376
- Specialty
- Biological Therapy
- Hematology
- Abstract
- In this book, world-renowned experts in the field of hematopoietic cell transplantation examine a range of issues and controversies relating to apheresis, with the aim of identifying current trends and best practices. Readers will find up-to-date guidance on donor evaluation, CD34+ cell mobilization strategies, options and selection of apheresis device, anticoagulation techniques in apheresis, the role of prediction algorithms in determining procedure eligibility and length, and the prevention and management of complications. Applications of apheresis devices in the processing of bone marrow grafts are discussed, and detailed attention is devoted to the indications and rationale for therapeutic apheresis procedures, with individual chapters focusing on therapeutic plasma exchange and immunoadsorption, red cell exchange, and extracorporeal photopheresis. Finally, the applications of apheresis in pediatric donors and in resource-limiting environments are considered. This book, featuring numerous helpful tables, algorithms, and figures, will be of high practical value for residents, fellows, faculty members and other healthcare personnel involved in hematopoietic cell transplantation.
- Contents
- 1. Introduction and Rationale -- 2. Administrative and Regulatory Considerations for Apheresis Collection Facilities -- 3. FACT-JACIE Standards: Common Citations and How Best to Avoid Them -- 4. Donor Evaluation for Hematopoietic Stem and Progenitor Cell Collection -- 5. Mobilization Strategies: HPC(A) Collections for Autologous Hematopoietic Cell Transplants -- 6. Mobilization Strategies: HPC(A) Collections for Allogeneic Hematopoietic Cell Transplants -- 7. Hematopoietic Progenitor Cells, Apheresis and Therapeutic Cells, T-Cells Collection: Instrumentation, Operating Parameters, and Troubleshooting -- 8. Anticoagulation and Other Periprocedural Considerations for Apheresis -- 9. Concepts and Rationale for Using Predictive Algorithms for Hematopoietic Progenitor Cell Apheresis Collection -- 10. Applications of Apheresis Devices in Processing Bone Marrow Grafts -- 11. Therapeutic Plasma Exchange and Immunoadsorption: Indications and Implementation -- 12. Red Blood Cell Exchange: When and Why? -- 13. Extracorporeal Photopheresis in Hematopoietic Cell Transplantation -- 14. Prevention and Management of Apheresis Complications -- 15. Challenges and Optimization of Apheresis Procedures in Resource-Limiting Environments.
- Format
- e-Book
- Location
- Online
Total Marrow Irradiation : A Comprehensive Review
https://libcat.nshealth.ca/en/permalink/provcat45231
Jeffrey Y. C. Wong, Susanta K. Hui, editors.
--Cham:
Springer
, c2020.
- Available Online
- View e-Book
- Location
- Online
This book, written by a team of international experts, concisely reviews the rationale and clinical application of image-guided total marrow irradiation, a rapidly emerging area in radiation oncology and hematopoietic cell transplantation. The aim is to provide the practicing radiation oncologist, hematologist, medical physicist, and bone marrow transplant researcher with a fundamental understanding of key aspects and an appreciation of the increasing significance of total marrow irradiation as…
- Available Online
- View e-Book
- Other Authors
- Wong, Jeffrey Y.C.
- Hui, Susanta K.
- Responsibility
- Jeffrey Y. C. Wong, Susanta K. Hui, editors
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2020
- Physical Description
- 1 online resource (vi, 196 p.) : 45 illus., 38 illus. in color
- ISBN
- 9783030386924
- 9783030386917 (Print ed.)
- 9783030386931 (Print ed.)
- 9783030386948 (Print ed.)
- Subjects (MeSH)
- Bone Marrow Neoplasms - radiotherapy
- Hematopoietic System - radiation effects
- Radiotherapy - methods
- Specialty
- Hematology
- Medical Oncology
- Radiotherapy
- Abstract
- This book, written by a team of international experts, concisely reviews the rationale and clinical application of image-guided total marrow irradiation, a rapidly emerging area in radiation oncology and hematopoietic cell transplantation. The aim is to provide the practicing radiation oncologist, hematologist, medical physicist, and bone marrow transplant researcher with a fundamental understanding of key aspects and an appreciation of the increasing significance of total marrow irradiation as conditioning for bone marrow transplantation. Detailed attention is paid to the impacts of recent advances in radiation therapy technology, functional PET and MRI, and understanding of the response of bone marrow to radiation. Full consideration is also given to the ways in which technological advances in image-guided radiation therapy have created new opportunities to treat bone marrow transplant patients with limited transplant options due to advanced disease, age, or co-morbidities. Further topics covered include the ways in which cancer stem cells and the marrow microenvironment influence response to radiation therapy and the implementation of new-generation predictive radiobiologic factors in the clinic.
- Contents
- 1. Total Marrow Irradiation: Redefining the Role of Radiotherapy in Bone Marrow Transplantation -- 2. Implementation of Targeted Total Body Irradiation as a Bone Marrow Transplant Conditioning Regimen: A Review -- 3 Radiobiologic Factors to Consider with Total Marrow Irradiation -- 4. Dose Escalation of Total Marrow and Lymphoid Irradiation in Advanced Acute Leukemia -- 5. Reduced Intensity Conditioning Regimens in Combination with Total Marrow and Lymphoid Irradiation -- 6. Total Marrow Irradiation and Total Lymphoid Irradiation in Lymphoma and Advanced Hematologic Malignancies: The Genoa Experience -- 7. Total Marrow/Lymphoid Irradiation in the Conditioning Regimen for Haploidentical T-Cell-Depleted Hematopoietic Stem Cell Transplantation for Acute Myeloid Leukemia: The Perugia Experience -- 8. Total Marrow and Lymphoid Irradiation in Haploidentical Hematopoietic Cell Transplant -- 9. Total Marrow Irradiation in Multiple Myeloma: The French Myeloma Group Experience -- 10. Total Marrow Irradiation in Multiple Myeloma -- 11. Linac-Based Total Marrow Irradiation (TMI) -- 12. Improved Clinical Outcome After Total Marrow Irradiation Conditioning Stem Cell Transplantation for Hematologic Malignancies -- 13. Modern Total Body Irradiation (TBI): Intensity-Modulated Radiation Treatment (IMRT) -- 14. Acute and Late Toxicities with Total Marrow Irradiation.
- Format
- e-Book
- Location
- Online
Imaging of Trabecular Microfracture and Bone Marrow Edema and Hemorrhage
https://libcat.nshealth.ca/en/permalink/provcat45312
Yong-Whee Bahk.
--Singapore:
Springer
, c2020.
- Available Online
- View e-Book
- Location
- Online
This excellently illustrated monograph summarizes the updated fresh information on the theoretical, practical, and rapidly extended facets of gamma correction 99mTc-hydroxymethylene diphosphonate pinhole bone scan (99mTc-GCPBS) to MRI, CR, and MDCT. Basically, 99mTc-GCPBS is able to precisely visualize and quantitate callused trabecular microfracture (CTMF) which is as little as 200 µm in size. The extended gamma correction images can very neatly demonstrate CTMF on MRI, conventional radiograph…
- Available Online
- View e-Book
- Author
- Bahk, Yong-Whee
- Responsibility
- Yong-Whee Bahk
- Place of Publication
- Singapore
- Publisher
- Springer
- Date of Publication
- c2020
- Physical Description
- 1 online resource (xvii, 146 p.) : 166 illus., 121 illus. in color
- ISBN
- 9789811544668
- 9789811544651 (Print ed.)
- 9789811544675 (Print ed.)
- 9789811544682 (Print ed.)
- Subjects (MeSH)
- Bone Marrow - injuries
- Cancellous Bone - injuries
- Fractures, Stress - diagnostic imaging
- Specialty
- Diagnostic Imaging
- Osteology
- Abstract
- This excellently illustrated monograph summarizes the updated fresh information on the theoretical, practical, and rapidly extended facets of gamma correction 99mTc-hydroxymethylene diphosphonate pinhole bone scan (99mTc-GCPBS) to MRI, CR, and MDCT. Basically, 99mTc-GCPBS is able to precisely visualize and quantitate callused trabecular microfracture (CTMF) which is as little as 200 µm in size. The extended gamma correction images can very neatly demonstrate CTMF on MRI, conventional radiography (CR), and multidetector computed tomography (MDCT). Whenever appropriate, histological correlation is provided in conjunction with fine gamma corrected images. In this setting, ACDSee 10 gamma correction MRI and CR have been found to offer a highly useful option that deserves wider clinical interest. In practice, gamma correction MRI, CR, and MDCT can distinctly visualize CTMF so that CTMF can be precisely measured simply using an optic lens. By comparison, the naïve MRI, for example, shows CTMF which measures as big as 2 mm in size. Furthermore, 99mTc-GCPBS can now differentiate bone marrow edema from hemorrhage using the visuospatial mathematic method, which includes the ImageJ of the NIH.
- Contents
- 1. Introduction -- 2. 99mTc-HDP Pinhole Bone Scanning -- 3. Gamma Correction -- 4. Gamma Correction 99mTc-HDP Pinhole Bone Scan of Trabecular Microfracture and Endosteal Rimming in Rat -- 5. Preoperative Radiograph and Gamma Correction 99mTc-HDP Pinhole Scan of Femoral Neck Fracture in Patients -- 6. Gamma Correction 99mTc-HDP Pinhole Bone Scan Demonstration of Callused Trabecular Microfracture -- 7. Gamma Correction 99mTc-HDP Pinhole Bone Scan of Callused Trabecular Microfracture in Surgical Specimen: Histological Validation -- 8. Mathematic and Magnifying Lens Measurements of 99mTc-HDP Uptake in Callused Trabecular Microfracture -- 9. Corroborative Analysis of Callused Trabecular Microfracture on 99mTc-HDP Pinhole Bone Scan, Surgical Specimen, GCPBS, and H&E Stain -- 10. ACDSee-10 Gamma Correction 99mTc-HDP Pinhole Bone Scan of Normal Adult Bone Skeleton Viewed from the Stand Point of Wolff’s Law -- 11. ACDSee-10 Gamma Correction MRI for Neat Imaging and Magnifying Lens Measurement of Callused Trabecular Microfracture -- 12. ACDSee-10 Gamma Correction Conventional Radiography for Demonstration and Size Measurement of Callused Trabecular Microfracture -- 13. ACDSee-10 Gamma Correction Multidetector Computed Tomographic Demonstration and Quantitation of Callused Trabecular Microfracture -- 14. Morphobiochemical Diagnosis of Callused Trabecular Microfracture Using Gamma Correction 99mTc-HDP Pinhole Bone Scan with Histological Validation -- 15. Differential Diagnosis of Bone Marrow Edema and Hemorrhage and Callused Trabecular Microfracture with Gamma Correction 99mTc-HDP Pinhole Bone Scan Validation -- 16. Miscellanea of Gamma Correction Medical Imaging.
- Format
- e-Book
- Location
- Online
Bone Marrow Biopsy Pathology : A Practical Guide
https://libcat.nshealth.ca/en/permalink/provcat45319
Christine Beham-Schmid, Annette Schmitt-Graeff.
--Berlin, Heidelberg:
Springer
, c2020.
- Available Online
- View e-Book
- Location
- Online
This comprehensive, superbly illustrated reference is designed to provide practical diagnostic assistance for hematopathologists when dealing with common and uncommon lesions in bone marrow trephine biopsies (BMTBs). At the heart of the book is a systematic analysis of neoplastic hematological and non-hematological disease entities, with concise identification of the key features of myeloproliferative neoplasms, myelodysplastic syndromes, acute and chronic leukemias, eosinophilia-associated mye…
- Available Online
- View e-Book
- Author
- Beham-Schmid, Christine
- Other Authors
- Schmitt-Graeff, Annette
- Responsibility
- Christine Beham-Schmid, Annette Schmitt-Graeff
- Place of Publication
- Berlin, Heidelberg
- Publisher
- Springer
- Date of Publication
- c2020
- Physical Description
- 1 online resource (xix, 533 p.) : 403 illus. in color
- Series Title
- Essentials of diagnostic pathology
- ISBN
- 9783662603093
- 9783662603079 (Print ed.)
- 9783662603086 (Print ed.)
- ISSN
- 2194-6256
- Subjects (MeSH)
- Biopsy
- Bone Marrow - pathology
- Bone Marrow Diseases - diagnosis
- Bone Marrow Neoplasms - diagnosis
- Specialty
- Hematology
- Medical Oncology
- Pathology
- Abstract
- This comprehensive, superbly illustrated reference is designed to provide practical diagnostic assistance for hematopathologists when dealing with common and uncommon lesions in bone marrow trephine biopsies (BMTBs). At the heart of the book is a systematic analysis of neoplastic hematological and non-hematological disease entities, with concise identification of the key features of myeloproliferative neoplasms, myelodysplastic syndromes, acute and chronic leukemias, eosinophilia-associated myeloid/lymphoid neoplasms, lymphoproliferative disorders, and selected non-hematopoietic malignancies. Relevant examples of BMTBs are presented, with microscopic description, high-quality photomicrographs, and clinical data. The book also explains how to assess hematopoietic and stromal components of normal BMTBs, identifies the heterogeneous patterns that may be observed in healthy individuals, and analyzes reactive conditions, with particular attention to diagnostic problems and pitfalls.
- Contents
- 1. Normal Bone Marrow -- 2. Non-neoplastic Conditions with Quantitative and Qualitative Changes in Hematopoiesis -- 3. Bone Changes Found in Bone Marrow Biopsies -- 4. Non-hematological Malignancies in the Bone Marrow -- 5. Increase of Plasma Cells, Reactive and Neoplastic -- 6. Inflammatory and Infectious Diseases -- 7. Malignant Lymphomas -- 8. Mastocytosis -- 9. Myeloproliferative Neoplasm (MPN) -- 10. Myeloid/Lymphoid Neoplasms with Eosinophilia and Rearrangement of PDGFRA, PDGFRB, FGFR1, or with PCM1-JAK2 -- 11. Myelodysplastic/Myeloproliferative Neoplasms (MDS/MPN) -- 12. Myelodysplastic Syndromes (MDS) -- 13. Acute Leukemia of Myeloid, Lymphoid, and Ambiguous Lineage and Related Malignancies.
- Format
- e-Book
- Location
- Online
Hematology in the Adolescent Female
https://libcat.nshealth.ca/en/permalink/provcat45337
Lakshmi V. Srivaths, editor.
--Cham:
Springer
, c2020.
- Available Online
- View e-Book
- Location
- Online
Adolescent females experience a variety of blood disorders that are often unique to this patient population. As they go through puberty, they are uniquely poised to encounter various bleeding and thrombotic disorders once they attain menarche, start to have menstrual bleeding, and require hormonal therapy. This may in turn lead to other medical conditions, such as anemia and iron deficiency. Pregnancy encountered by some adolescents can pose hematologic challenges specifically in regards to ble…
- Available Online
- View e-Book
- Other Authors
- Srivaths, Lakshmi V.
- Responsibility
- Lakshmi V. Srivaths, editor
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2020
- Physical Description
- 1 online resource (xv, 329 p.)
- ISBN
- 9783030484460
- 9783030484453 (Print ed.)
- 9783030484477 (Print ed.)
- 9783030484484 (Print ed.)
- Subjects (MeSH)
- Adolescent
- Hematologic Diseases
- Women's Health
- Specialty
- Adolescent Medicine
- Gynecology
- Hematology
- Abstract
- Adolescent females experience a variety of blood disorders that are often unique to this patient population. As they go through puberty, they are uniquely poised to encounter various bleeding and thrombotic disorders once they attain menarche, start to have menstrual bleeding, and require hormonal therapy. This may in turn lead to other medical conditions, such as anemia and iron deficiency. Pregnancy encountered by some adolescents can pose hematologic challenges specifically in regards to bleeding and thrombotic disorders. In addition, adolescent females are at risk to develop immune mediated hematologic disorders, such as immune thrombocytopenia, auto-immune hemolytic anemia, and thrombotic thrombocytopenic purpura, as well as vitamin deficiencies due to pernicious anemia. Sickle cell disease, thalassemia and bone marrow failure disorders in the adolescent female poses unique challenges that need to be addressed with special care and attention. Knowledge about these various blood disorders in adolescent females is crucial for the treating physician in order to accurately diagnose and optimally manage these teenagers. Otherwise, it can affect their overall health, causing hematologic and gynecologic issues, poor quality of life, neurocognitive impairments, and poor psycho-social development, all of which can lead to various complications immediately and into adulthood. This book provides a comprehensive, state-of-the art overview of blood disorders in female adolescents. The text presents new data about bleeding disorders that affect the female adolescent, including bleeding disorders, thromboembolism, thrombophilia, anemia, sickle cell disease and thalassemia, disorders od hemostasis and thrombosis in pregnancy, immune hematology and bone marrow failure disorders; reviews our current understanding of these disorders; outlines recent research findings; and spotlights multi-disciplinary approaches, evaluation and treatment modalities to combat these blood disorders. Written by experts in the field, Hematology in the Adolescent Female is a valuable resource for clinicians and practitioners who treat and manage female adolescents with blood disorders.
- Contents
- Part I. Bleeding Disorders and Heavy Menstrual Bleeding -- 1. Evaluation of the Adolescent with Heavy Menstrual Bleeding -- 2. Screening Tools for Evaluating the Bleeding Adolescent -- 3. von Willebrand Disease -- 4. Hemophilia Carriers -- 5. Rare Coagulation Factor Deficiencies -- 6. Platelet Disorders in the Adolescent Female -- 7. Fibrinolytic Pathway Disorders -- 8. Hypermobility Syndromes in Heavy Menstrual Bleeding -- 9. Complications of Heavy Menstrual Bleeding in Adolescents -- 10. Hormonal Therapy for Heavy Menstrual Bleeding -- 11. Hemostatic Therapies for Heavy Menstrual Bleeding -- 12. Quality of Life in Female Adolescents with Bleeding Disorders -- Part II. Thromboembolism in the Adolescent Female -- 13. Prevalence and Risk Factors of Adolescent Venous Thromboembolism -- 14. Diagnosis, Prevention, and Management of Venous Thromboembolism in the Adolescent Female -- 15. Thrombophilia and Hormonal Therapy in Adolescents -- 16. Heavy Menstrual Bleeding and Anticoagulation -- Part III Anemia in the Adolescent Female -- 17. Iron Deficiency Anemia -- 18. Vitamin B12 Deficiency -- Part IV. Hemoglobinopathies in the Adolescent Female -- 19. Thalassemia Disorders in the Adolescent Female -- 20. Sickle Cell Disease in the Adolescent Female -- Part V. Immune Hematology in the Adolescent Female -- 21. Immune Thrombocytopenia in Adolescents -- 22. Autoimmune Hemolytic Anemia in Adolescent Females -- 23. Evans Syndrome in the Adolescent Female -- 24. Antiphospholipid Syndrome -- 25. Thrombotic Microangiopathy in the Adolescent Female -- Part VI. Bone Marrow Failure Disorders in the Adolescent Female -- 26. Bone Marrow Failure Disorders in the Adolescent Female -- Part VII. Blood Disorders in the Pregnant Adolescent -- 27. Adolescent Pregnancy Complicated by Thrombosis -- 28. Bleeding Disorders in Pregnancy.
- Format
- e-Book
- Location
- Online
Practical Lymph Node and Bone Marrow Pathology : Frequently Asked Questions
https://libcat.nshealth.ca/en/permalink/provcat45408
Endi Wang, Anand Shreeram Lagoo, editors.
--Cham:
Springer
, c2020.
- Available Online
- View e-Book
- Location
- Online
This book provides a step-by-step and practically applicable approach for the accurate and clinically relevant diagnosis of lymph node (LN) and bone marrow (BM) biopsies. Clinicians expect pathological guidance not only with accurate diagnosis, but also about disease progression, minimal residual disease, disease susceptibility to a particular therapy, effects of prior therapy on prognosis and subsequent therapy etc. This book provides brief but to the point guidance about the prognostic and th…
- Available Online
- View e-Book
- Other Authors
- Wang, Endi
- Lagoo, Anand Shreeram
- Responsibility
- Endi Wang, Anand Shreeram Lagoo, editors
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2020
- Physical Description
- 1 online resource (xiii, 752 p.) : 356 illus., 352 illus. in color
- Series Title
- Practical anatomic pathology
- ISBN
- 9783030321895
- 9783030321888 (Print ed.)
- 9783030321901 (Print ed.)
- 9783030321918 (Print ed.)
- Subjects (MeSH)
- Bone Marrow - pathology
- Bone Marrow Diseases - diagnosis
- Lymph Nodes - pathology
- Lymphatic Diseases - diagnosis
- Specialty
- Hematology
- Pathology
- Abstract
- This book provides a step-by-step and practically applicable approach for the accurate and clinically relevant diagnosis of lymph node (LN) and bone marrow (BM) biopsies. Clinicians expect pathological guidance not only with accurate diagnosis, but also about disease progression, minimal residual disease, disease susceptibility to a particular therapy, effects of prior therapy on prognosis and subsequent therapy etc. This book provides brief but to the point guidance about the prognostic and therapeutic implications of key ancillary studies so that the pathologist is comfortable to answer clinician’s questions over the entire arc of manifestations and management of the disease. The text follows the WHO (2016) classification in essence but the material is organized in a fashion most useful to a practicing surgical pathologist. This is achieved by focusing on the morphological findings as the starting point. Using this morphological “backbone” and several frequently asked questions (FAQs) the reader is guided to a rational list of differential diagnoses leading to a definitive diagnosis. The contents of each chapter are carefully selected so that the practically important and directly applicable information is available in an easy-to-find and easy-to-grasp format. Practical Lymph Node and Bone Marrow Pathology serves as a practical introduction and handbook for pathology trainees and hematopathology fellows and will remain a useful reference to practicing pathologists when they are signing out lymph nodes or bone marrow specimens.
- Contents
- Essentials of the Immune Response and Immunophenotyping -- Molecular Genetics and Cell Biology for Hematopathology -- Evaluation of Excised Lymph Nodes -- Lymphoid Pathology on Small Biopsies (FNA and Small Core) – Advantages and Limitations: Guidelines for Ancillary Studies According to Clinical Scenario and Morphology -- Small B-Cell Lymphomas With and Without Plasmacytic Differentiation -- Large B-Cell Lymphoma -- High-Grade B-Cell Lymphoma -- Major Subtypes of Mature T- and NK-cell Neoplasms -- Hodgkin Lymphomas -- Post-Transplant Lymphoproliferative Disorders (PTLD) -- Immunodeficiency-Associated Lymphoproliferative Disorders Other Than PTLD (In Primary Immune Deficiency, HIV, and Iatrogenic Conditions) -- Primary Extranodal Lymphomas of GI Tract, Lung, CNS and Skin With Common Mimics -- Lymphoid Neoplasms With “Benign” Clinical Course or Unclear Malignant Potential -- B-Cell Lymphoma in Children or Pediatric Type -- Indolent T/NK-Cell Lymphoproliferative Disorders -- Composite Lymphoma -- Histiocytic/Dendritic Cell Neoplasms: Primary and Transdifferentiated -- Typical Morphologic Patterns of Infectious and Other Reactive Lymphadenopathies -- HHV8-Associated Lymphoproliferative Disorders -- Bone Marrow at Initial Diagnosis: Clinical Associations and Approach to Diagnosis -- Acute Leukemias -- Chronic Myeloid Leukemia -- Chronic Myeloproliferative Neoplasms (Other Than Chronic Myeloid Leukemia) -- Myelodysplastic Syndromes -- Myelodysplastic/Myeloproliferative Neoplasms -- Plasma Cell Neoplasms (Including Plasma Cell Myeloma) -- Bone Marrow Involvement by Lymphoid Neoplasms -- Bone Marrow Involvement by Metastases and Granulomatous Conditions -- Bone Marrow Findings in Congenital/Hereditary Conditions -- Bone Marrow Involvement by More Than One Entity of Hematolymphoid Neoplasm -- Detection of Minimal Residual Disease -- Therapy Induced Marrow Changes.
- Format
- e-Book
- Publication Type
- Handbook
- Location
- Online
Pediatric Hematopoietic Stem Cell Transplantation for Pharmacists : The Gold Standard to Practice
https://libcat.nshealth.ca/en/permalink/provcat45573
Carolina Witchmichen Penteado Schmidt.
--Cham:
Springer
, c2020.
- Available Online
- View e-Book
- Location
- Online
This unique book is the first on pediatric hematopoietic stem cell transplantation that is especially intended for pharmacists – in recognition of the fact that Pediatric Oncology Pharmacy is an area where more and more specific knowledge is required in daily practice, yet pharmacists who work in pediatric stem cell transplantation do not have a book addressing their specific needs. This pioneering book will likely become the new gold standard for practice, addressing subjects such as stem cell…
- Available Online
- View e-Book
- Responsibility
- Carolina Witchmichen Penteado Schmidt
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2020
- Physical Description
- 1 online resource (xiii, 123 p.)
- ISBN
- 9783030434915
- 9783030434908 (Print ed.)
- 9783030434922 (Print ed.)
- Subjects (MeSH)
- Child
- Hematopoietic Stem Cell Transplantation
- Pharmacy - methods
- Abstract
- This unique book is the first on pediatric hematopoietic stem cell transplantation that is especially intended for pharmacists – in recognition of the fact that Pediatric Oncology Pharmacy is an area where more and more specific knowledge is required in daily practice, yet pharmacists who work in pediatric stem cell transplantation do not have a book addressing their specific needs. This pioneering book will likely become the new gold standard for practice, addressing subjects such as stem cells and their differentiation mechanisms; aspects of embryonic and non-embryonic stem cells; stem cell transplantation in pediatrics; stem cell sources and related technical choices; stem cell donors; scheduling transplantations; diseases and chemotherapy protocols that require stem cell transplantation; stem cell homing; engraftment and repopulation of stem cells in bone marrow; autologous stem cell transplantation in pediatrics; allogeneic stem cell transplantation in pediatrics; and indications for autologous and allogeneic pediatric stem cell transplantation. Further, it discusses pediatric graft-versus-host disease and the pharmacist; antibacterial and antifungal prophylaxis; detailed chemotherapy, conditioning and trials for pediatric stem cell transplantation; conditioning granulocyte colony-stimulating factor (G-CSF) in pediatric stem cell transplantation; analyzing prescriptions and programming a pediatric stem cell transplantation; handling chemotherapy and adjuvant drugs for pediatric stem cell transplantation; stem cell transplantation in children up to 1 year old; and clinical pharmacy in pediatric stem cell transplantation. An easy-to-read yet comprehensive guide covering a wide range of topics essential to daily practice, the book offers an invaluable asset for pediatric hemato/ oncology pharmacists, hematologist pharmacists, clinical pharmacists, pediatric pharmacists, pharmaceutical residents and researchers alike.
- Contents
- The pharmacist in pediatric hematopoietic stem cell transplantation -- Stem cells -- Stem cell transplantation in pediatrics -- Homing of stem cells to the bone marrow: finding the way home -- Pediatric graft-versus-host disease (GvHD) and the pharmacist -- Antibacterial, antifungal and antiviral prophylaxis for children undergoing HSCT -- Peripheral blood stem cell mobilization in pediatric stem cell transplantation -- Reprogrammed cells in pediatric HSCT -- Stem cell transplantation in children up to 1 year old -- Clinical pharmacy in pediatric stem cell transplantation.
- Format
- e-Book
- Location
- Online
Bone marrow test
https://libcat.nshealth.ca/en/permalink/chpams36757
Nova Scotia Health Authority. QEII. Hematology Clinic.
Halifax, NS:
Nova Scotia Health Authority
, 2020.
- Pamphlet Number
- 0100
- Available Online
- View Pamphlet
Your doctor has arranged for you to have a bone marrow test. This test helps your doctor diagnose and treat your medical problem. This pamphlet explains what a bone marrow test is, how to get ready for the test, where and how the test is done, and what will happen after the test. A list of symptoms that require immediate medical attention is provided.
- Available Online
- View Pamphlet
- Corporate Author
- Nova Scotia Health Authority. QEII. Hematology Clinic
- Place of Publication
- Halifax, NS
- Publisher
- Nova Scotia Health Authority
- Date of Publication
- 2020
- Format
- Pamphlet
- Language
- English
- Physical Description
- 1 electronic document (5 p.) : digital, PDF file
- Subjects (MeSH)
- Bone Marrow
- Diagnostic Techniques and Procedures
- Subjects (LCSH)
- Bone marrow
- Diagnostic specimens--Collection and preservation
- Specialty
- Hematology
- Abstract
- Your doctor has arranged for you to have a bone marrow test. This test helps your doctor diagnose and treat your medical problem. This pamphlet explains what a bone marrow test is, how to get ready for the test, where and how the test is done, and what will happen after the test. A list of symptoms that require immediate medical attention is provided.
- Responsibility
- Prepared by: 8AB/BMT/Medical Day Unit/Hematology Clinic
- Pamphlet Number
- 0100
Oncology Management Guidelines : Natural Health Products
https://libcat.nshealth.ca/en/permalink/chpams37433
Nova Scotia Health. Cancer Care Program.
[Halifax, NS]:
Nova Scotia Health Cancer Care Program
, 2020.
- Pamphlet Number
- 1691
- Available Online
- View Pamphlet
The use of natural health products during chemotherapy, cellular therapy (including bone marrow transplantation), or surgery is not recommended. This pamphlet defines natural health products and outlines Nova Scotia Health's guidelines on the use of natural health products during chemotherapy.
- Available Online
- View Pamphlet
- Corporate Author
- Nova Scotia Health. Cancer Care Program
- Place of Publication
- [Halifax, NS]
- Publisher
- Nova Scotia Health Cancer Care Program
- Date of Publication
- 2020
- Format
- Pamphlet
- Language
- English
- Physical Description
- 1 electronic document : digital, PDF file
- Subjects (MeSH)
- Complementary Therapies
- Dietary Supplements
- Neoplasms - therapy
- Subjects (LCSH)
- Alternative medicine
- Cancer--Treatment
- Dietary supplements
- Specialty
- Complementary Therapies
- Abstract
- The use of natural health products during chemotherapy, cellular therapy (including bone marrow transplantation), or surgery is not recommended. This pamphlet defines natural health products and outlines Nova Scotia Health's guidelines on the use of natural health products during chemotherapy.
- Responsibility
- prepared by Nova Scotia Health Authority Pharmacy Services ; approved by Nova Scotia Cancer Patient Education Committee & Oncology Therapy Subcommittee
- Pamphlet Number
- 1691
