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Advanced Procedures for Pain Management : A Step-by-Step Atlas

https://libcat.nshealth.ca/en/permalink/provcat43113
Sudhir Diwan, Timothy R. Deer, editors. --Cham: Springer , c2018.
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Edited by Sudhir Diwan, a former Director of Pain Medicine fellowship program at Ivy League Weill Cornell Medical College, and Timothy R. Deer, an internationally renowned expert in neuromodulation and minimally invasive spinal procedures, this atlas covers advanced procedures that normal residency and fellowship programs may not cover. It consolidates information pain fellows usually amass by traveling throughout the country to various specialized weekend courses. Advanced Procedures for Inter…
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Other Authors
Diwan, Sudhir
Deer, Timothy R.
Responsibility
Sudhir Diwan, Timothy R. Deer, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2018
Physical Description
1 online resource (xviii, 606 p.) : 267 illus., 197 illus. in color
ISBN
9783319688411
9783319688398 (print ed.)
9783319688404 (print ed.)
Subjects (MeSH)
Electric Stimulation Therapy
Orthopedic Procedures
Pain Management - methods
Regenerative Medicine - methods
Specialty
Pain Management
Abstract
Edited by Sudhir Diwan, a former Director of Pain Medicine fellowship program at Ivy League Weill Cornell Medical College, and Timothy R. Deer, an internationally renowned expert in neuromodulation and minimally invasive spinal procedures, this atlas covers advanced procedures that normal residency and fellowship programs may not cover. It consolidates information pain fellows usually amass by traveling throughout the country to various specialized weekend courses. Advanced Procedures for Interventional Pain Management: A Step-by-Step Atlas is for physicians that know the fundamentals of pain medicine and want to push their knowledge further. Through easy-to-digest bullet points, extensive diagrams, hundreds of figures, and expanded legends beneath each illustration, this compendium covers techniques such as uoroscopic guidance and radiation safety, endoscopic transforaminal discectomy, endoscopic direct-percutaneous discectomy, transforaminal myelogram, percutaneous facet fusion, percutaneous sacroplasty, vertebral augmentations, percutaneous tumor ablation, percutaneous spinal fusion, minimally invasive spinal decompression (MILD), Interspinous Spacer Placement and advanced neuroaugmentation techniques like high frequency stimulation and DRG stimulation. This book also has a dedicated section on Regenerative Medicine with chapters on platelet rich plasma, stem cell therapy, and intradiscal regenerative therapy. Each chapter has a strict chapter format that includes the indications and contraindications for each procedure, a list of equipment and drugs, a step-by-step illustration-focused how-to, a list of possible post-procedural complications, and bullet-pointed clinical pearls and pitfalls. Within each chapter the authors will also cover the variations of each procedure due to different equipment. This book is ideal for pain medicine fellows, spine surgeons, and interventional pain physicians who want access to the best minds and specialized procedures in a single package.
Contents
Section I: Advanced Spinal Interventions -- 1. Advanced Spinal Mapping: An Interventional Continuum for Axial, Radicular, and Dorsal Root Ganglion-Related Pain -- 2. MILD: Percutaneous Lumbar Decompression -- 3. Superion: An Indirect Lumbar Decompression -- 4. Minimally Invasive Discectomy: Transforaminal Approach -- 5. Minimally Invasive Percutaneous Endoscopic Discectomy: Transdiscal Approach -- 6. Minimally Invasive Facet Fusion -- 7. Vertebral Augmentation: Vertebroplasty and Kyphoplasty -- Section II: Advanced Neuromodulation -- 8. Neuromodulation: Mechanisms of Action -- 9. Anatomy of Neuromodulatory Targets: Central Nervous System and the Periphery -- 10. Neuromodulation: Optimizing Surgical Outcomes and Risk Reduction -- 11. Extracranial Peripheral Nerve and Peripheral Nerve Field Stimulation for Headache: Trialing -- 12. Extracranial Peripheral Nerve Field and Peripheral Nerve Stimulation for Headache: Permanent Implant -- 13. Intracranial Neuromodulation: Deep Brain Stimulation for Pain -- 14. Spinal Cord Stimulation, Cervical: Trialing -- 15. Spinal Cord Stimulation: Thoracic and Lumbar Trial -- 16. Spinal Cord Stimulation Hybrid Lead Array: Epidural and Peripheral Nerve Field Stimulation Trial -- 17. Hybrid Neuromodulation -- 18. Permanent Percutaneous Spinal Cord Stimulator Implantation: Cervical/Lumbar -- 19. Spinal Cord Stimulation for Chronic Abdominal Pain -- 20. Spinal Cord Stimulation: Pelvic Pain -- 21. Truncal Stimulation Trial and Implant -- 22. Peripheral Nerve Stimulation for the Painful Extremity -- 23. Advanced Neuromodulation Techniques: Dorsal Root Ganglion Stimulation -- 24. High-Frequency Stimulation -- 25. Burst Stimulation: An Innovative Waveform Strategy for Spinal Cord Stimulation -- 26. Novel Waveforms -- 27. Transcutaneous Vagus Nerve Stimulation: Novel Treatment Strategies -- 28. Sacral Stimulation for Pelvic Pain -- 29. Intrathecal Drug Delivery: Pharmacokinetics and Dynamics -- 30. Patient Selection for Drug Delivery System Implantation -- 31. Intrathecal Drug Delivery: Medication Selection -- 32. Intrathecal Drug Delivery: Trialing -- 33. Intrathecal Drug Delivery: Implantation -- 34. Intrathecal Drug Delivery Maintenance: Refill and Programming -- 35. Intrathecal Drug Delivery Maintenance: Catheter Evaluation -- 36. Intrathecal Drug Delivery: Innovation -- Section III: Advanced Regenerative Medicine -- 37. History of Regenerative Medicine -- 38. Platelet-Rich Plasma -- 39. Alpha-2-Macroglobulin: Protease Inhibitor Treatment (PRP Variant) -- 40. Bone Marrow Derived Stem Cells and their Application in Pain Medicine -- 41. Adipose-Derived Stromal Stem Cells -- 42. Intradiscal Biologic Treatments: Allogeneic Stem Cells -- 43. Intradiscal Biologic Treatments: Intra-annular Fibrin Disc Sealant -- 44. Amniotic Tissue -- 45. Platelet-Rich Plasma (PRP): Procedural Techniques for Musculoskeletal Injuries -- 46. Technical Aspects of Regenerative Injection Therapy -- 47. Platelet-Rich Plasma Therapy: An Overview.
Format
e-Book
Publication Type
Atlas
Location
Online
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Agammaglobulinemia

https://libcat.nshealth.ca/en/permalink/provcat39385
Alessandro Plebani, Vassilios Lougaris, editors. (1st ed.) --Cham: Springer , c2015.
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This book provides an updated overview of agammaglobulinemia, a rare form of primary immunodeficiency which is considered the prototype of the congenital humoral defects, and which is characterized by the absence of peripheral B cells and very low serum immunoglobulin levels. The book opens by discussing the highly orchestrated early B cell development in the bone marrow and the genes involved based on both human and animal models. The pathogenesis and clinical presentation of X-linked agammagl…
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Other Authors
Plebani, Alessandro
Lougaris, Vassilios
Responsibility
Alessandro Plebani, Vassilios Lougaris, editors
Edition
1st ed.
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2015
Physical Description
1 online resource (ix, 119 p. : 22 illus., 18 illus. in color)
Series Title
Rare diseases of the immune system
ISBN
9783319227146
9783319227139 (print ed.)
ISSN
2282-6505
Subjects (MeSH)
Agammaglobulinemia
Abstract
This book provides an updated overview of agammaglobulinemia, a rare form of primary immunodeficiency which is considered the prototype of the congenital humoral defects, and which is characterized by the absence of peripheral B cells and very low serum immunoglobulin levels. The book opens by discussing the highly orchestrated early B cell development in the bone marrow and the genes involved based on both human and animal models. The pathogenesis and clinical presentation of X-linked agammaglobulinemia, caused by mutations in the BTK (Bruton's tyrosine kinase) gene, are then presented in detail, followed by descriptions of the clinical manifestations and molecular basis of the less frequent autosomal recessive and autosomal dominant forms of agammaglobulinemia. Patients' management in terms of respiratory complications, gammaglobulin replacement therapy and the potential value of novel experimental therapeutic strategies are discussed. The book's closing chapters offer a comprehensive and updated description of mutations in the BTK gene, and the expression and function of BTK in cells other than B cells.
Contents
Early B Cell Biology -- Agammaglobulinemia: Basic Pathogenesis and Clinical Spectrum -- Pulmonary Pathology in Agammaglobulinemia: Diagnosis and Treatment -- Immunoglobulin Replacement Therapy: Past, Present, Future -- Genetic Variation in Bruton Tyrosine Kinase -- Novel Therapeutic Options for X-Linked Agammaglobulinemia -- Bruton’s Tyrosine Kinase (BTK) Beyond B Lymphocytes: A Protein Kinase with Relevance in Innate Immunity.
Format
e-Book
Location
Online
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ALERT – adverse late effects of cancer treatment. Volume 1, General concepts and specific precepts

https://libcat.nshealth.ca/en/permalink/provcat33390
Philip Rubin, Louis S. Constine, Lawrence B. Marks, editors. --Heidelberg: Springer , c2014.
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The literature on the late effects of cancer treatment is widely scattered in different journals since all major organ systems are affected and management is based on a variety of medical and surgical treatments. The aim of ALERT Adverse Late Effects of Cancer Treatment is to offer a coherent multidisciplinary approach to the care of cancer survivors. The central paradigm is that cytotoxic multimodal therapy results in a perpetual cascade of events that affects each major organ system different…
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Other Authors
Rubin, Philip
Constine, Louis S
Marks, Lawrence B
Responsibility
Philip Rubin, Louis S. Constine, Lawrence B. Marks, editors
Alternate Title
Adverse late effects of cancer treatment
Place of Publication
Heidelberg
Publisher
Springer
Date of Publication
c2014
Physical Description
1 online resource (xxiv, 311 pages)
Series
Medical radiology. Radiation oncology
Series Title
Medical radiology (Series)
ISBN
9783540723141 (electronic bk.)
9783540723134
Subjects (MeSH)
Antineoplastic Agents - adverse effects
Radiotherapy - adverse effects
Radiation Injuries
Subjects (LCSH)
Cancer - Treatment - Complications
Antineoplastic Agents - adverse effects
Radiotherapy - adverse effects
Abstract
The literature on the late effects of cancer treatment is widely scattered in different journals since all major organ systems are affected and management is based on a variety of medical and surgical treatments. The aim of ALERT Adverse Late Effects of Cancer Treatment is to offer a coherent multidisciplinary approach to the care of cancer survivors. The central paradigm is that cytotoxic multimodal therapy results in a perpetual cascade of events that affects each major organ system differently and is expressed continually over time. Essentially, radiation and chemotherapy are intense biologic modifiers that allow for cancer cure and cancer survivorship but accelerate senescence of normal tissues and increase the incidence of age-related diseases and second malignant tumors. Volume 1 of this two-volume work focuses on the general concepts and principles relevant to late effects and on the dynamic interplay of molecular, cytologic and histopathologic events that lead to altered physiologic and metabolic functions and their clinical manifestations. Chapters are also included on legal issues, economic aspects, nursing, psychological issues and quality of life.
Contents
Prologue: Surviving Cancer: SEER Statistics -- Biocontinuum of the Pathophysiology Paradigm -- Biophysiopathology of the Microvasculature and Microcirculation -- Molecular Mechanisms of Radiation Induced Injury -- Biodetection and Biointervention: Cytokine Pathways as a Rationale for Anti-Cytokine Interventions Post-Radiation -- Quantitative/Objective Analyses of RT-Induced Late Normal Tissue Injury Using Functional Imaging -- Biograding of Normal Tissue TNM Toxicity Taxonomy: Scoring the Adverse Effects of Cancer Treatment -- Understanding and Predicting Radiation-Associated Normal Tissue Injury: A Global and Historical Perspective -- Biotoxicity of Chemotherapy -- BioSurveillance and Longitudinal Lifelong Guidelines -- BioPediatric Complexities of Growth and Development -- BioGenetic and Host Implications -- Bioengineering of Irradiated Normal Tissues by Bone Marrow Stem Cells -- Radiotherapy-Induced Carcinogenesis and Leukemogenesis: Mechanisms and Quantitative Modeling -- The Bioepidemiology of MultiplePrimary Cancers -- Radiation-Related Second Primary Cancers: Clinical Perspectives -- The Psychosocial and Functional Impact of Radiation Therapy -- Nursing -- Economic Consequences of Late Effects -- Radiological and Nuclear Terrorism: Relevance to the Radiation Oncology and Biology Communities.
Format
e-Book
Location
Online
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Amyloid and Related Disorders : Surgical Pathology and Clinical Correlations

https://libcat.nshealth.ca/en/permalink/provcat39337
Maria M. Picken, Guillermo A. Herrera, Ahmet Dogan, editors. (Second edition) --Cham: Springer International Publishing : Imprint: Humana Press , c2015.
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The second edition of this text presents an overview of the most recent developments in this area including clinical presentation, etiology, pathogenesis, and differential diagnosis. The rationale for various therapies, including transplantation, is discussed and tissue diagnosis (its pitfalls and strategies for avoiding them) and laboratory support are included. The involvement of all major organ systems including renal/genitourinary, cardiac, gastrointestinal, pulmonary, peripheral nerve/cent…
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Other Authors
Picken, Maria M
Herrera, Guillermo A
Dogan, Ahmet
Responsibility
Maria M. Picken, Guillermo A. Herrera, Ahmet Dogan, editors
Edition
Second edition
Place of Publication
Cham
Publisher
Springer International Publishing : Imprint: Humana Press
Date of Publication
c2015
Physical Description
1 online resource (xix, 542 p. : 391 illus., 345 illus. in color)
Series Title
Current clinical pathology
ISBN
9783319192949
9783319192932 (print ed.)
ISSN
2197-781X
Subjects (MeSH)
Amyloid - adverse effects
Amyloidosis - diagnosis
Amyloidosis - pathology
Amyloidosis - therapy
Abstract
The second edition of this text presents an overview of the most recent developments in this area including clinical presentation, etiology, pathogenesis, and differential diagnosis. The rationale for various therapies, including transplantation, is discussed and tissue diagnosis (its pitfalls and strategies for avoiding them) and laboratory support are included. The involvement of all major organ systems including renal/genitourinary, cardiac, gastrointestinal, pulmonary, peripheral nerve/central nervous system, soft tissue, skin, lymph node/spleen and bone marrow pathology is also covered. Amyloid and Related Disorders, Second Edition will be invaluable to specialized and general pathologists as well as cytopathologists. Other medical professionals may also benefit from this concise update on the systemic amyloidoses.
Contents
[publisher supplied] Introduction/general -- Aspects of the history and nomenclature of amyloid and amyloidosis -- Amyloid diseases at the molecular level: general overview and focus on AL amyloidosis -- AA amyloidosis -- Non-Immunoglobulin and non-AA amyloidoses -- The hereditary amyloidoses -- Dialysis-associated amyloidosis -- Localized amyloidoses and amyloidoses associated with aging outside the central nervous system -- Central nervous system amyloid -- Non-amyloid protein deposits -- Differential diagnosis of amyloid in surgical pathology: organized deposits and other material in the differential diagnosis of amyloidosis -- Light /heavy chain deposition disease as a systemic disease -- Glomerulonephritis with non-organized monoclonal immunoglobulin deposits -- Pathologies of renal and systemic intracellular paraprotein storage: crystalopathies and beyond -- Diagnosis -- Diagnosis of amyloid using Congo red: polarized and fluorescence -- Thioflavin T stain for amyloid detection -- Fat tissue analysis in the management of patients with systemic amyloidosis -- Generic diagnosis of amyloid: recent developments and summary of current recommendations -- Amyloid typing on formalin-fixed paraffin sections by immunohistochemistry: experience from two large referral centers -- Options for amyloid typing in renal pathology: the advantages of frozen section immunofluorescence -- Amyloid typing by immuno-electron microscopy -- Classification of amyloidosis by mass spectrometry-based proteomics -- Summary and practical recommendation regarding amyloid typing using antibody-based and proteomic methods -- Ancillary studies of amyloidosis -- Laboratory support for diagnosis of amyloidosis -- Bone marrow biopsy and its utility in the diagnosis of AL amyloidosis and other plasma cell dyscrasias -- Molecular methods for the diagnosis of hereditary amyloidosis -- Radiologic support for diagnosis and monitoring of amyloidosis: established techniques and recent developments -- Organ involvement in amyloidoses -- Amyloidoses of the Kidney and Genitourinary tract -- Cardiac amyloidosis -- Amyloidosis of the Gastrointestinal tract and Liver -- Peripheral nerve amyloidosis -- Amyloidoses of the Pulmonary and upper respiratory tract -- Amyloidoses involving the skin -- Clinical issues and therapy -- Clinico-pathologic issues in patients with amyloidosis -- Solid organ transplantation in amyloidosis and issues pertaining to domino liver transplantation -- Emerging therapies for amyloidosis -- Clinical trials -- Modern therapies in AA amyloidosis -- Medico legal issues of amyloidosis -- Amyloidosis from the patient's perspective.
Format
e-Book
Location
Online
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Atlas of Adult Autopsy : A Guide to Modern Practice

https://libcat.nshealth.ca/en/permalink/provcat40026
S. Kim Suvarna, editor. (1st ed.) --Cham: Springer , c2016.
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This atlas leads the reader through the adult autopsy process, and its common variations, with a large number of high-quality macroscopic photographs and concise accompanying text. It provides a manual of current practice and is an easy-to-use resource for case examination for consent, medico-legal and radiological autopsies. External realities and checks are discussed at the beginning of the book, which goes on to cover specific body cavities and organ systems in detail. The book ends with cha…
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Other Authors
Suvarna, S. Kim
Responsibility
S. Kim Suvarna, editor
Edition
1st ed.
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2016
Physical Description
1 online resource (xi, 399 p. : 1100 illus., 1066 illus. in color)
ISBN
9783319270227
9783319270203 (print ed.)
Subjects (MeSH)
Adult
Autopsy - methods
Abstract
This atlas leads the reader through the adult autopsy process, and its common variations, with a large number of high-quality macroscopic photographs and concise accompanying text. It provides a manual of current practice and is an easy-to-use resource for case examination for consent, medico-legal and radiological autopsies. External realities and checks are discussed at the beginning of the book, which goes on to cover specific body cavities and organ systems in detail. The book ends with chapters on topics including forensic autopsies, specialist sampling, toxicology analyses and the radiological autopsy. Atlas of Adult Autopsy is aimed at practicing pathologists, particularly those in training grades. It may also be of interest to anatomical technicians in autopsy suites, as well as parties with a legal interest in autopsy practice.
Contents
General Considerations and Safety -- External Examination -- Evisceration -- Thorax: Heart, Lungs, Mediastinum, and Pleura -- Gastrointestinal and Hepatobiliary System -- Genitourinary and Breast Tissues, Including Pregnancy -- Lymphoreticular Tissues: Lymph Node, Spleen and Thymus, Bone and Marrow -- Endocrine Glands: Thyroid, Parathyroid, Adrenal, and Pituitary -- The Central Nervous System, with Eye and Ear -- Standard and Special Tests -- Devices: Foreign Items Encountered During the Autopsy -- The Forensic Autopsy -- The Radiological Autopsy -- Toxicology -- Appendix.
Format
e-Book
Publication Type
Atlas
Location
Online
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Atlas of Bone Marrow Pathology

https://libcat.nshealth.ca/en/permalink/provcat42928
Tracy I. George, Daniel A. Arber, editors. --New York, NY: Springer , c2018.
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This text illustrates bone marrow aspirate, imprint and biopsy specimens showing characteristic features of a wide variety of neoplastic and non-neoplastic conditions. While the focus is on Wright-stained smears and hematoxylin-eosin stained biopsies, other key histochemical and immunohistochemical stains are illustrated that are vital for proper diagnosis. After a brief review of the normal bone marrow, reactive changes in the marrow are illustrated, including the bone marrow response in const…
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Other Authors
George, Tracy I.
Arber, Daniel A.
Responsibility
Tracy I. George, Daniel A. Arber, editors
Place of Publication
New York, NY
Publisher
Springer
Date of Publication
c2018
Physical Description
1 online resource (xiv, 293 p.) : 560 illus., 555 illus. in color
Series Title
Atlas of anatomic pathology
ISBN
9781493974696
9781493974672 (print ed.)
9781493974689 (print ed.)
9781493984954 (print ed.)
ISSN
2625-3372
Subjects (MeSH)
Bone Marrow Diseases - physiopathology
Bone Marrow - pathology
Specialty
Hematology
Pathology
Abstract
This text illustrates bone marrow aspirate, imprint and biopsy specimens showing characteristic features of a wide variety of neoplastic and non-neoplastic conditions. While the focus is on Wright-stained smears and hematoxylin-eosin stained biopsies, other key histochemical and immunohistochemical stains are illustrated that are vital for proper diagnosis. After a brief review of the normal bone marrow, reactive changes in the marrow are illustrated, including the bone marrow response in constitutional disorders and to metabolic changes throughout the body. This is followed by specific infectious disorders in the marrow and other non-neoplastic disorders. The remainder of the Atlas illustrates the various neoplasms that involve the bone marrow, including leukemias, lymphomas and non-hematopoietic neoplasms. The hematologic neoplasms are classified using the 2016 World Health Organization (WHO) classification. This overview of bone marrow disorders illustrates a wide variety of diseases that practicing pathologists and hematologists will encounter in their routine practice.
Contents
Normal Bone Marrow -- Reactive Changes -- Post-Therapy Marrow Changes -- Constitutional, Metabolic and Related Disorders -- Bone Marrow Infections -- Bone Marrow Lymphoma -- Plasma Cell Neoplasms -- Immunodeficiency-Associated Lymphoproliferative Disorder -- Lymphoblastic Leukemia/Lymphoma -- Myelodysplastic Syndrome -- Acute Myeloid Leukemia -- Myeloid Proliferations of Down Syndrome -- Acute Leukemias of Ambiguous Lineage -- Histiocytic Disorders -- Myeloproliferative Neoplasms and Mastocytosis -- Myeloid and Lymphoid Neoplasms with Eosinophilia -- Myelodysplastic/Myeloproliferative Neoplasms (MDS/MPN) -- Metastatic Tumors in Bone Marrow.
Format
e-Book
Publication Type
Atlas
Location
Online
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Basics of Planning and Management of Patients during Radiation Therapy : A Guide for Students and Practitioners

https://libcat.nshealth.ca/en/permalink/provcat43094
Ashutosh Mukherji. --Singapore: Springer , c2018.
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This book summarizes the do's and don'ts of managing a patient receiving radiotherapy as well as how to manage common day to day situations that one comes across in radiation oncology practice. It serves as a useful guide for radiation oncology practitioners for practical exams. This book offers assistance to young radiotherapists in handling cancer patients.
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Author
Mukherji, Ashutosh
Responsibility
Ashutosh Mukherji
Place of Publication
Singapore
Publisher
Springer
Date of Publication
c2018
Physical Description
1 online resource (xvii, 403 p.) : 88 illus., 86 illus. in color
ISBN
9789811066597
9789811066580 (print ed.)
9789811066603 (print ed.)
Subjects (MeSH)
Neoplasms - radiotherapy
Patient Care Planning
Radiotherapy
Treatment Outcome
Specialty
Radiotherapy
Abstract
This book summarizes the do's and don'ts of managing a patient receiving radiotherapy as well as how to manage common day to day situations that one comes across in radiation oncology practice. It serves as a useful guide for radiation oncology practitioners for practical exams. This book offers assistance to young radiotherapists in handling cancer patients.
Contents
Part I. Approaching a Cancer Patient -- 1. Taking a Decision and Ordering Investigations -- 2. Role of Surgery in Cancer Management -- 3. Radiotherapy in Cancer Care -- 4. Role of Chemotherapy in Management of Cancers -- 5. Principles of Management of Cancers in Paediatric Patients -- 6. Palliative and Supportive Care of Cancers -- Part II. Principles of Application of Radiotherapy -- 7. Radiobiological Principles -- 8. Patient’s Positioning and Simulation: Do’s and Don’ts -- 9. Planning a Patient, Deciding on the Volumes and Fields and Plan Verification -- 10. Conformal Radiotherapy: Simulation and Contouring -- 11. Prescribing a Radiotherapy Schedule and Dose Fractionation -- 12. Evaluating a Treatment Plan -- 13. An Introduction to Brachytherapy -- 14. Brachytherapy Planning and Evaluation -- 15. Planning Electron Therapy and Evaluation of Plans -- 16. Planning Stereotactic and Adaptive Radiotherapy -- 17. Intraoperative Radiotherapy -- 18. Particle Beam Therapy: A Quick View -- Part III. Use of Other Agents with Radiation -- 19. Using Concurrent or Sequential Chemotherapy and Biomolecules -- 20. Use of Radiosensitizers and Radioprotectors -- Part IV. Managing Radiotherapy Complications -- 21. Expected Complications During Treatment -- 22. Management of Oral Mucosal Reactions and Oro-dental Care -- 23. Management of Skin Reactions -- 24. Management of GI Complications -- 25. Managing Local Pain -- 26. Managing Bone Marrow Toxicities -- 27. Managing Complications: Lymphoedema and Fibrosis -- 28. Dietary Care and Support During Radiotherapy -- 29. Post-treatment Evaluation and Advice and Follow-Up Schedules -- 30. Psychological and Social Issues in Patients Undergoing Radiotherapy.
Format
e-Book
Location
Online
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Benign Hematologic Disorders in Children : A Clinical Guide

https://libcat.nshealth.ca/en/permalink/provcat46337
Deepak M. Kamat, Melissa Frei-Jones, editors. --Cham: Springer , c2021.
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Access
NEW Springer 2021
Location
Online
This book provides a comprehensive overview of benign hematologic disorders in children. Divided into nine sections, the text reviews common hematologic disorders or conditions that affect children, while providing state-of-the-art information on pathophysiology, diagnosis, treatment, and management strategies. The text begins with a section on hematopoiesis, and the next section covers red blood cell disorders. The following sections provide overviews of platelet disorders, white blood cell di…
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Other Authors
Kamat, Deepak M.
Frei-Jones, Melissa
Responsibility
Deepak M. Kamat, Melissa Frei-Jones, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2021
Physical Description
1 online resource (xiii, 512 p.)
ISBN
9783030499808
9783030499792 (Print ed.)
9783030499815 (Print ed.)
9783030499822 (Print ed.)
Subjects (MeSH)
Child
Hematologic Diseases
Specialty
Hematology
Pediatrics
Abstract
This book provides a comprehensive overview of benign hematologic disorders in children. Divided into nine sections, the text reviews common hematologic disorders or conditions that affect children, while providing state-of-the-art information on pathophysiology, diagnosis, treatment, and management strategies. The text begins with a section on hematopoiesis, and the next section covers red blood cell disorders. The following sections provide overviews of platelet disorders, white blood cell disorders, and coagulation disorders. The sixth and seventh sections discuss neonatal hematology and bone marrow failure syndrome. The eighth section reviews supportive care, while the final section covers miscellaneous subjects including pediatric vascular anomalies and complement dysregulation syndromes. Written by experts in the field, Benign Hematologic Disorders in Children: A Clinical Guide is a valuable resource for clinicians and practitioners who treat children afflicted with these disorders.
Contents
Part I. Origin of Blood Cells -- Hematopoiesis -- Part II. Red Blood Cell Disorders -- Nutritional Anemias: Iron Deficiency and Megaloblastic Anemia -- Lead Poisoning -- Immune and Non-Immune Hemolytic Anemia -- Sickle Cell Disease -- Thalassemia -- Disorders of RBC Metabolism -- Red blood cell membrane defects -- Part III. Platelet disorders -- Immune Thrombocytopenia -- Inherited and Congenital Thrombocytopenia -- Platelet Disorders -- Thrombocytosis in Children -- Part IV. WBC disorders -- Neutropenia -- Granulocytosis -- Disorders of Granulocyte Functions -- Part V. Coagulation Disorders -- Von Willebrand Disease -- Hemophilia -- Acquired Disorders of Coagulation in Neonates and Children -- Thromboembolism -- Heavy Menstrual Bleeding and Bleeding Disorders in Adolescents: A Primer for the Primary Care Physician -- Part VI. Neonatal Hematology -- Newborn Screening for Hemoglobinopathies -- Neonatal Immune Hemolytic Anemia -- Neonatal Hemostasis Disorders of Bilirubin Metabolism -- Part VII. Bone Marrow Failure Syndrome -- Failure of Erythrocyte Production -- Inherited Bone Marrow Failure Syndromes -- What Pediatricians Need to Know about Acquired Aplastic Anemia -- Part VIII. Supportive Care -- Immunizations in the Child with Sickle Cell Disease -- Transfusion Medicine for Pediatrics -- Management of infections in neutropenic patients -- Part IX. Miscellaneous -- Pediatric Vascular Anomalies: Opportunities in Primary Care -- Complement Dysregulation Syndromes in Children and Adolescents.
Access
NEW Springer 2021
Format
e-Book
Location
Online
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Best Practices in Processing and Storage for Hematopoietic Cell Transplantation

https://libcat.nshealth.ca/en/permalink/provcat43148
Joseph Schwartz, Beth H. Shaz, editors. --Cham: Springer , c2018.
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Online
This concise book examines clinically relevant issues relating to the ways in which bone marrow, cord blood and apheresis products, are processed and stored for the purpose of Hematopoietic Cell Transplantation and Cell Therapy. The twin aims are to offer up-to-date content covering a wide spectrum of topics and controversies and to provide practitioners in the field of transplant and cell therapy with practical, immediately applicable information from the internationally experts in the field. …
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Other Authors
Schwartz, Joseph
Shaz, Beth H.
Responsibility
Joseph Schwartz, Beth H. Shaz, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2018
Physical Description
1 online resource (vi, 160 p.) : 19 illus., 10 illus. in color
Series Title
Advances and controversies in hematopoietic transplantation and cell therapy
ISBN
9783319589497
9783319589480 (print ed.)
9783319589503 (print ed.)
9783319865171 (print ed.)
ISSN
2569-1376
Subjects (MeSH)
Cord Blood Stem Cell Transplantation
Hematopoietic Stem Cell Transplantation
Specimen Handling - methods
Specialty
Clinical Laboratory Techniques
Hematology
Regenerative Medicine
Abstract
This concise book examines clinically relevant issues relating to the ways in which bone marrow, cord blood and apheresis products, are processed and stored for the purpose of Hematopoietic Cell Transplantation and Cell Therapy. The twin aims are to offer up-to-date content covering a wide spectrum of topics and controversies and to provide practitioners in the field of transplant and cell therapy with practical, immediately applicable information from the internationally experts in the field. Each chapter focuses on a particular subject, and numerous working tables, algorithms, and figures are included. Whenever appropriate, the reader's attention is drawn to the availability of potentially high-impact clinical trials and expert practices. The authors are all experts who have been carefully selected for their knowledge of the topics that they address. The book will appeal to clinical and laboratory personnels, residents, fellows, and faculty members responsible for the care of hematopoietic cell transplant products and patients. Its format ensures that it will also serve as a robust, engaging tool to aid vital activities in every hematology and oncology trainee's daily work.
Contents
Journey of Hematopoietic Cells: Procurement to Infusion -- Regulations & Accreditation of Processing Laboratories -- Part I: HPC, Apheresis and HPC, Marrow: Donor qualification -- Routine HPC Apheresis & Marrow processing -- CD34 Enrichment /T-cell depletion -- Cryopreservation: Techniques, Freezing Solutions -- Hematopoietic Cell Graft Thawing—Best Practices -- Part II: HPC, Cord Blood: CB Donor Qualification -- Cord Blood Processing -- Cord Blood Graft Assessment -- Cord Blood Graft Thawing - Best Practices -- Hematopoietic Graft Handling during Transportation.
Format
e-Book
Location
Online
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Best Practices of Apheresis in Hematopoietic Cell Transplantation

https://libcat.nshealth.ca/en/permalink/provcat45065
Syed A. Abutalib, Anand Padmanabhan, Huy P. Pham, Nina Worel, editors. --Cham: Springer , c2020.
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Location
Online
In this book, world-renowned experts in the field of hematopoietic cell transplantation examine a range of issues and controversies relating to apheresis, with the aim of identifying current trends and best practices. Readers will find up-to-date guidance on donor evaluation, CD34+ cell mobilization strategies, options and selection of apheresis device, anticoagulation techniques in apheresis, the role of prediction algorithms in determining procedure eligibility and length, and the prevention …
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Other Authors
Abutalib, Syed A.
Padmanabhan, Anand
Pham, Huy P.
Worel, Nina
Responsibility
Syed A. Abutalib, Anand Padmanabhan, Huy P. Pham, Nina Worel, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2020
Physical Description
1 online resource (vi, 211 p.) : 33 illus., 29 illus. in color
Series Title
Advances and controversies in hematopoietic transplantation and cell therapy
ISBN
9783319551319
9783319551302 (Print ed.)
9783319551326 (Print ed.)
ISSN
2569-1376
Subjects (MeSH)
Blood Component Removal - methods
Hematopoietic Stem Cell Transplantation - methods
Specialty
Biological Therapy
Hematology
Abstract
In this book, world-renowned experts in the field of hematopoietic cell transplantation examine a range of issues and controversies relating to apheresis, with the aim of identifying current trends and best practices. Readers will find up-to-date guidance on donor evaluation, CD34+ cell mobilization strategies, options and selection of apheresis device, anticoagulation techniques in apheresis, the role of prediction algorithms in determining procedure eligibility and length, and the prevention and management of complications. Applications of apheresis devices in the processing of bone marrow grafts are discussed, and detailed attention is devoted to the indications and rationale for therapeutic apheresis procedures, with individual chapters focusing on therapeutic plasma exchange and immunoadsorption, red cell exchange, and extracorporeal photopheresis. Finally, the applications of apheresis in pediatric donors and in resource-limiting environments are considered. This book, featuring numerous helpful tables, algorithms, and figures, will be of high practical value for residents, fellows, faculty members and other healthcare personnel involved in hematopoietic cell transplantation.
Contents
1. Introduction and Rationale -- 2. Administrative and Regulatory Considerations for Apheresis Collection Facilities -- 3. FACT-JACIE Standards: Common Citations and How Best to Avoid Them -- 4. Donor Evaluation for Hematopoietic Stem and Progenitor Cell Collection -- 5. Mobilization Strategies: HPC(A) Collections for Autologous Hematopoietic Cell Transplants -- 6. Mobilization Strategies: HPC(A) Collections for Allogeneic Hematopoietic Cell Transplants -- 7. Hematopoietic Progenitor Cells, Apheresis and Therapeutic Cells, T-Cells Collection: Instrumentation, Operating Parameters, and Troubleshooting -- 8. Anticoagulation and Other Periprocedural Considerations for Apheresis -- 9. Concepts and Rationale for Using Predictive Algorithms for Hematopoietic Progenitor Cell Apheresis Collection -- 10. Applications of Apheresis Devices in Processing Bone Marrow Grafts -- 11. Therapeutic Plasma Exchange and Immunoadsorption: Indications and Implementation -- 12. Red Blood Cell Exchange: When and Why? -- 13. Extracorporeal Photopheresis in Hematopoietic Cell Transplantation -- 14. Prevention and Management of Apheresis Complications -- 15. Challenges and Optimization of Apheresis Procedures in Resource-Limiting Environments.
Format
e-Book
Location
Online
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Biologics in orthopaedic surgery

https://libcat.nshealth.ca/en/permalink/provcat42509
Augustus D. Mazzocca, Adam D. Lindsay. --St. Louis, MI: Elsevier , c2019.
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Location
Online
Designed with the practicing clinician in mind, Biologics in Orthopaedic Surgery provides a succinct, easy-to-digest overview of the integration of biologics (platelet-rich-plasma [PRP], bone marrow aspirate [BMA], and stem cells) into today’s orthopaedic practice. Covering relevant basic science as well as clinical applications, this concise reference takes a head-to-toe approach to the emerging role of orthobiologics for specific conditions and procedures, in addition to future directions fo…
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Author
Mazzocca, Augusts D.
Other Authors
Lindsay, Adam D.
Responsibility
Augustus D. Mazzocca, Adam D. Lindsay
Alternate Title
Biologics in orthopedic surgery
Orthopedic procedures
Operative techniques
Place of Publication
St. Louis, MI
Publisher
Elsevier
Date of Publication
c2019
Physical Description
1 online resource, 234 p.
Series Title
Operative techniques
ISBN
9780323551403
Subjects (MeSH)
Orthopedic Procedures
Biological Products - therapeutic use
Specialty
Orthopedic Procedures
Regenerative Medicine
Abstract
Designed with the practicing clinician in mind, Biologics in Orthopaedic Surgery provides a succinct, easy-to-digest overview of the integration of biologics (platelet-rich-plasma [PRP], bone marrow aspirate [BMA], and stem cells) into today’s orthopaedic practice. Covering relevant basic science as well as clinical applications, this concise reference takes a head-to-toe approach to the emerging role of orthobiologics for specific conditions and procedures, in addition to future directions for implementation.
Access
Registration required for PDF access.
Format
e-Book
Publication Type
Atlas
Location
Online
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Biology and Treatment of Leukemia and Bone Marrow Neoplasms

https://libcat.nshealth.ca/en/permalink/provcat47145
Vinod Pullarkat, Guido Marcucci. Springer , 2021.
Available Online
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Location
Online
Available Online
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Responsibility
Vinod Pullarkat, Guido Marcucci
Publisher
Springer
Date of Publication
2021
Physical Description
1 online resource (viii, 196 pages) : illustrations
Series Vol.
181
Series Title
Cancer treatment and research
ISBN
9783030783112
Specialty
Hematology
Medical Oncology
Format
e-Book
Location
Online
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Biology of blood and marrow transplantation

https://libcat.nshealth.ca/en/permalink/provcat15796
Carden Jennings
Access
.
Holdings
Nova Scotia Hospital: v. 9, 2003 - v. 10, 2004.
Location
Nova Scotia Hospital
Publisher
Carden Jennings
Holdings
Nova Scotia Hospital: v. 9, 2003 - v. 10, 2004.
ISSN
1083-8791
Specialty
Hematology and Transfusion
Transplantation
Access
.
Format
Journal
Location
Nova Scotia Hospital
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Biology of blood and marrow transplantation

https://libcat.nshealth.ca/en/permalink/provcat51478
Elsevier
Available Online
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Holdings
v. 13, 2007 - v.26 2020
Location
Online
Available Online
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Publisher
Elsevier
Holdings
v. 13, 2007 - v.26 2020
ISSN
1083-8791
Format
e-Journal
Location
Online
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Biology of blood and marrow transplantation

https://libcat.nshealth.ca/en/permalink/provcat19450
American Society for Blood and Marrow Transplantation
Available Online
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Holdings
Vol 13, 2007 -
Location
Online
Available Online
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Publisher
American Society for Blood and Marrow Transplantation
Holdings
Vol 13, 2007 -
Publication Frequency
Monthly
ISSN
1083-8791
Specialty
Regenerative Medicine
Transplantation
Format
e-Journal
Location
Online
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Biomarkers of the Tumor Microenvironment : Basic Studies and Practical Applications

https://libcat.nshealth.ca/en/permalink/provcat41337
Lars A. Akslen, Randolph S. Watnick, editors. --Cham: Springer , 2017.
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Location
Online
This book reviews different aspects of the cancer microenvironment, and its regulation and importance for tumor progression. Practical applications, in terms of how biomarkers are increasingly included in therapy protocols, will also be discussed. Biomarkers of the Tumour Microenvironment: Basic Studies and Practical Applications is aimed at research pathologists in the cancer field, and also cancer researchers from other backgrounds, especially those using morphology techniques and models focu…
Available Online
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Other Authors
Akslen, Lars A
Watnick, Randolph S
Responsibility
Lars A. Akslen, Randolph S. Watnick, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
2017
Physical Description
1 online resource (xvii, 534 pages) : 52 illus., 51 illus. in color
ISBN
9783319391472
9783319391458 (print ed.)
Subjects (MeSH)
Biomarkers, Tumor
Tumor Microenvironment
Abstract
This book reviews different aspects of the cancer microenvironment, and its regulation and importance for tumor progression. Practical applications, in terms of how biomarkers are increasingly included in therapy protocols, will also be discussed. Biomarkers of the Tumour Microenvironment: Basic Studies and Practical Applications is aimed at research pathologists in the cancer field, and also cancer researchers from other backgrounds, especially those using morphology techniques and models focusing on cross-talk between different cell types in tumors.
Contents
Part I: Basic Mechanisms and Biomarkers -- 1. The Role of the Tumor Microenvironment in Regulating Angiogenesis -- 2. More Than a Barrier: How the Endothelium Instructs Metastasis -- 3. Tissue-Based Biomarkers of Tumor-Vascular Interactions -- 4. Role of the Extracellular Matrix in Tumor Stroma: Barrier or Support? -- 5. Stromal PDGF Receptors as Prognostic and Predictive Biomarkers -- 6. The Function and Diagnostic Potential of Adipocyte-Derived Factors in the Tumor Microenvironment -- 7. Inflammation and Cancer: The Role of Lipid Signaling in the Continuum Between Two Ends of the Tumor Spectrum -- 8. Cancer Immunity and Immune Evasion Mechanisms -- 9. Drivers of EMT and Immune Evasion -- 10. Inflammatory Biomarkers for Cancer -- 11. Immunology of Solid Tumors Beyond Tumor-Infiltrating Lymphocytes: The Role of Tertiary Lymphoid Structures -- 12. The Role of Platelets in the Tumor Microenvironment -- 13. Regulation of Tumor Progression and Metastasis by Bone Marrow-Derived Microenvironments -- 14. Neuropilin 1 and Neuropilin 2: Cancer Progression and Biomarker Analysis -- 15. The Role of Axl Receptor Tyrosine Kinase in Tumor Cell Plasticity and Therapy Resistance -- Part II: Organ Related Biomarker Studies -- 16. Gene Expression Signatures of the Tumor Microenvironment: Relation to Tumor Progress in Breast Cancer -- 17. MR-Derived Biomarkers for Cancer Characterization -- 18. The Influence of Tissue Architecture on Drug Response: Anticancer Drug Development in High-Dimensional Combinatorial Microenvironment Platforms -- 19. Models of Tumor Progression in Prostate Cancer -- 20. Tumor-Host Interactions in Malignant Gliomas -- 21. The Tumor Microenvironment in Cutaneous Melanoma: Friend or Foe -- 22. Biomarker Panels and Contemporary Practice in Clinical Trials of Targeted Therapy.
Format
e-Book
Location
Online
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Blood and Marrow Transplant Handbook

https://libcat.nshealth.ca/en/permalink/provcat46597
Richard T. Maziarz, Susan Schubach Slater. (Third edition) Springer , 2021.
Available Online
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Location
Online
Available Online
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Responsibility
Richard T. Maziarz, Susan Schubach Slater
Edition
Third edition
Publisher
Springer
Date of Publication
2021
Physical Description
1 online resource (xx, 1006 pages) : illustrations
ISBN
9783030536268
Specialty
Hematology
Transplantation
Format
e-Book
Location
Online
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Blood and Marrow Transplant Handbook : Comprehensive Guide for Patient Care

https://libcat.nshealth.ca/en/permalink/provcat39171
Richard T. Maziarz, Susan Schubach Slater, editors. (Second edition) --Cham: Springer , c2015.
Available Online
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Location
Online
This updated and expanded edition developed by the Blood and Marrow Stem Cell Transplant team at Oregon Health & Science University Knight Cancer Institute features the latest medical management guidelines and standards of care for hematopoietic stem cell transplant patients. Spanning the timeline from the initial consultation throughout the transplant process, this handbook includes indications for transplantation and donor selection, treatment guidelines for addressing complications during an…
Available Online
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Other Authors
Maziarz, Richard T
Slater, Susan Schubach
Responsibility
Richard T. Maziarz, Susan Schubach Slater, editors
Edition
Second edition
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2015
Physical Description
1 online resource (xiii, 444 p. : 21 illus., 9 illus. in color)
ISBN
9783319138329
9783319138312 (print ed.)
Subjects (MeSH)
Bone Marrow Transplantation
Hematopoietic stem cell transplantation
Patient Care Management
Abstract
This updated and expanded edition developed by the Blood and Marrow Stem Cell Transplant team at Oregon Health & Science University Knight Cancer Institute features the latest medical management guidelines and standards of care for hematopoietic stem cell transplant patients. Spanning the timeline from the initial consultation throughout the transplant process, this handbook includes indications for transplantation and donor selection, treatment guidelines for addressing complications during and after transplant, and recommendations for long-term follow up care. Concise, comprehensive, and easy-to-use, Blood and Marrow Transplant Handbook, 2nd Edition presents a multidisciplinary approach to information for physicians and advanced practice medical providers who care for transplant patients, and also residents, fellows, and other trainees.
Contents
Part 1: The Nuts and Bolts of Stem Cell Transplantation -- 1: Overview of Hematopoietic Stem Cell Transplantation -- 2: The Business of Cellular Therapy and Hematopoietic Stem Cell Transplantation -- 3: Hematopoietic Stem Cell Sources and Donor Selection -- 4: Pre-transplant Medical Evaluation -- 5: Social work: Evaluation and Patient Supports -- 6: Conditioning Regimens -- 7: Nutrition -- 8: Physical and Occupational Therapy -- 9: Adolescent and Young Adult (AYA) Concerns -- 10: Infection Prophylaxis -- 11: Graft-versus-Host Disease Prophylaxis -- 12: Transfusion Medicine -- 13: Antithrombotic Guidelines -- 14: Engraftment -- 15: Follow-up Care -- Part 2: Transplant Complications and Ongoing Care -- 16: Radiology Pearls for the Transplant Provider -- 17: Infectious Complications -- 18: Acute Graft-versus-Host Disease -- 19: Chronic Graft-versus-Host Disease -- 20: Oral Complications -- 21: Gastrointestinal Complications -- 22: Pulmonary Complications -- 23: Cardiovascular Complications -- 24: Kidney Disease in Hematopoietic Stem Cell Transplantation -- 25: Neurologic Complications -- 26: Endocrine Complications in Childhood Cancer Survivors -- 27: Thrombotic Microangiopathies -- 28: Women's Hormonal Health Issues -- 29: Psychiatric Complications -- 30: Graft Failure -- 31: Secondary Malignancies -- 32: Post-Transplant Relapse -- 33: Palliative Care -- 34: Long-Term Follow Up and Survivorship -- Appendix 1: The language of transplant -- Appendix 2: Procedure: Bone marrow aspirate and biopsy -- Appendix 3: Procedure: Lumbar puncture -- Appendix 4: Procedure: Ommaya -- Appendix 5: Procedure: Skin biopsy -- Appendix 6: OHSU Low Bacteria Diet -- Appendix 7: OHSU Graft-versus-Host Disease (GVHD) Diet.
Format
e-Book
Location
Online
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The BMT data book

https://libcat.nshealth.ca/en/permalink/provcat27772
Reinhold Munker, Hillard M. Lazarus, Kerry Atkinson. (2nd ed.) --Cambridge: Cambridge University Press , 2009.
Available Online
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Location
Online
Available Online
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Author
Munker, Reinhold
Other Authors
Lazarus, Hillard M
Atkinson, Kerry
Responsibility
Reinhold Munker, Hillard M. Lazarus, Kerry Atkinson
Edition
2nd ed.
Place of Publication
Cambridge
Publisher
Cambridge University Press
Date of Publication
2009
Physical Description
1 online resource (528 p.)
Series Title
Cambridge medicine
ISBN
9780511575525 (ebook)
9780521711005 (paperback)
Subjects (MeSH)
Bone Marrow Transplantation
Hematopoietic stem cell transplantation
Treatment Outcome
Format
e-Book
Location
Online
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The BMT data book : including cellular therapy

https://libcat.nshealth.ca/en/permalink/provcat26052
edited by Reinhold Munker ... [et al.]. (3rd ed.) --Cambridge, England: Cambridge University Press , c2013.
Call Number
WH 380 B661 2013
Location
Dickson Building
"This is an essential guide to the data, basic science, outcome studies and decision-making processes involved in blood and marrow stem cell transplantation. Organized according to disease types and procedures, it contains more than 100 tables, figures and algorithms that reflect up-to-date research and give guidance on the choices between different types of chemotherapy, autologous vs. allogeneic transplantation, peripheral blood vs. bone marrow stem cells, and standard vs. experimental treatm…
Call Number
WH 380 B661 2013
Other Authors
Munker, Reinhold
Responsibility
edited by Reinhold Munker ... [et al.]
Edition
3rd ed.
Alternate Title
Bone marrow transplantation data book
Place of Publication
Cambridge, England
Publisher
Cambridge University Press
Date of Publication
c2013
Physical Description
543 p.
ISBN
9781107617551
Subjects (MeSH)
Bone Marrow Transplantation
Hematopoietic stem cell transplantation
Treatment Outcome
Abstract
"This is an essential guide to the data, basic science, outcome studies and decision-making processes involved in blood and marrow stem cell transplantation. Organized according to disease types and procedures, it contains more than 100 tables, figures and algorithms that reflect up-to-date research and give guidance on the choices between different types of chemotherapy, autologous vs. allogeneic transplantation, peripheral blood vs. bone marrow stem cells, and standard vs. experimental treatments. This new edition summarizes the research of the last four years and gives mature data for all established indications, such as acute myeloid leukemia, myelodysplastic syndrome and Hodgkin and non-Hodgkin lymphomas. New chapters discuss global trends in stem cell transplantation, cellular therapies including donor lymphocytes, and pediatric neurologic and metabolic disorders. With an expanded complications section, links to electronic databases and discussion of new drugs and alternative stem cell sources, this text belongs in every transplant unit."--Provided by publisher.
Contents
Preface -- Part I. Basic Science -- 1. Hematopoietic cell transplantation: past, present and future -- 2. Basic science -- Part II. Hematologic Malignancies -- 3. Therapeutic decision making in BMT/SCT for acute myeloid leukemia -- 4. Therapeutic decision making in BMT/SCT for acute lymphoblastic leukemia -- 5. Therapeutic decision making in BMT/SCT for chronic myeloid leukemia and other myeloproliferative syndromes -- 6. Therapeutic decision making in BMT/SCT for chronic lymphatic leukemia -- 7. Therapeutic decision making in BMT/SCT for myelodysplasia -- 8. Hematopoietic cell transplantation for non-Hodgkin lymphoma -- 9. Therapeutic decision making in BMT/SCT for Hodgkin lymphoma -- 10. Therapeutic decision making in hematopoietic stem cell transplantation for multiple myeloma -- 11. Therapeutic decision making in SCT for amyloidosis -- Part III. Solid Tumors -- 12. Therapeutic decision making in BMT/SCT for nonseminomatous germ cell tumor of testis (NSGCT) -- 13. Therapeutic decision making in BMT/SCT for renal cell cancer -- 14. Therapeutic decision making in BMT/SCT for soft tissue sarcomas -- Part IV. Nonmalignant Disorders -- 15. Therapeutic decision making in BMT/SCT for severe aplastic anemia -- 16. Therapeutic decision making in BMT/SCT for congenital immunodeficiencies -- 17. Therapeutic decision making in BMT/SCT for hemoglobinopathies -- 18. Hematopoietic stem cell transplantation for inborn errors of metabolism and neurodegenerative disorders -- 19. Therapeutic decision making in BMT/SCT for autoimmune disorders -- 20. Cellular therapy -- Part V. Practical Aspects and Procedures -- 21. Practical aspects and procedures, including conditioning protocols and haploidentical transplantation -- 22. Umbilical cord blood as alternative allogeneic graft source: clinical banking and transplant outcomes -- Part VI. Complications -- 23. Pathobiology of graft-versus-host disease -- 24. Diagnosis and treatment of graft-versus-host-disease -- 25. Management and prophylaxis of infections after BMT/SCT -- 26. Organ-related and miscellaneous complications -- Part VII. The BMT/SCT Pharmacopoeia -- 27. The BMT/SCT pharmacopoeia -- Part VIII. HLA-Testing and Laboratory Medicine -- 28. HLA-testing and laboratory medicine -- Appendix: guide to the internet and literature databases relevant for bone marrow and stem cell transplantation -- Index.
Format
Book
Location
Dickson Building
Loan Period
3 weeks
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