ACL Injury and Its Treatment
https://libcat.nshealth.ca/en/permalink/provcat40415
Mitsuo Ochi, Konsei Shino, Kazunori Yasuda, Masahiro Kurosaka, editors.
--Tokyo:
Springer Japan
, c2016.
- Available Online
- View e-Book
- Location
- Online
This volume presents detailed information on surgically relevant anatomy and histology of the anterior cruciate ligament (ACL), biomechanics, diagnostics, and ACL reconstruction. In light of the growing body of evidence demonstrating the advantages of anatomic ACL reconstruction over traditional methods, there are also discussions of single anteromedial bundle reconstruction and anatomic ACL reconstruction with abundant descriptions of experimental and clinical studies. In addition, particular …
- Available Online
- View e-Book
- Other Authors
- Ochi, Mitsuo
- Shino, Konsei
- Yasuda, Kazunori
- Kurosaka, Masahiro
- Responsibility
- Mitsuo Ochi, Konsei Shino, Kazunori Yasuda, Masahiro Kurosaka, editors
- Place of Publication
- Tokyo
- Publisher
- Springer Japan
- Date of Publication
- c2016
- Physical Description
- 1 online resource (xiv, 562 p. : 255 illus., 182 illus. in color)
- ISBN
- 9784431558583
- 9784431558569 (print ed.)
- Subjects (MeSH)
- Anterior Cruciate Ligament - injuries
- Anterior Cruciate Ligament Reconstruction - methods
- Anterior Cruciate Ligament - surgery
- Knee Joint - anatomy & histology
- Abstract
- This volume presents detailed information on surgically relevant anatomy and histology of the anterior cruciate ligament (ACL), biomechanics, diagnostics, and ACL reconstruction. In light of the growing body of evidence demonstrating the advantages of anatomic ACL reconstruction over traditional methods, there are also discussions of single anteromedial bundle reconstruction and anatomic ACL reconstruction with abundant descriptions of experimental and clinical studies. In addition, particular attention is given not only to techniques such as ACL augmentation, bone-patella tendon-bone reconstruction and computer-assisted navigation, but it also presents expert analysis of revision of ACL reconstruction, complications, and the future perspectives of ACL reconstruction. Edited by authoritative orthopedic surgeon from the Japanese Orthopaedic Society of Knee, Arthroscopy and Sports Medicine (JOSKAS), this book provides up-to-date information for orthopedic surgeons and physical therapists specializing in the ACL. The research evidence will broaden readers' understanding and enable them to optimize outcomes for patients. As ACL rupture is a common injury especially for high-level athletes, it will also attract sports trainers and team physicians who are interested in a recent update on this field.
- Contents
- Part I. Anatomy and Histology of the ACL -- 1 Functional Anatomy of the ACL Fibers on the Femoral Attachment -- 2 The Anatomical Features of ACL Insertion Sites and Their Implications for Multi-Bundle Reconstruction -- 3 Discrepancy Between Macroscopic and Histological Observations -- 4 Tibial Insertion of the ACL: 3D-CT Images, Macroscopic, and Microscopic Findings -- 5 Mechanoreceptors in the ACL -- Part II. Biomechanics of the ACL -- 6 Mechanical Properties and Biomechanical Function of the ACL -- 7 Biomechanics of the Knee with Isolated One Bundle Tear of the Anterior Cruciate Ligament -- 8 Function and Biomechanics of ACL Remnant -- 9 Biomechanics of Single- and Double-Bundle ACL Reconstruction -- 10 ACL Injury Mechanisms -- Part III. Diagnostics of ACL Injury -- 11 Physical Examinations and Device Measurements for ACL Deficiency -- 12 Diagnostics of ACL Injury Using Magnetic Resonance Imaging (MRI) -- 13 Diagnosis of Injured ACL Using Three-Dimensional Computed Tomography: Usefulness for Preoperative Decision Making -- Part IV. Basic Knowledge of ACL Reconstruction -- 14 Graft Selection -- 15 Portal Placement -- 16 Femoral Bone Tunnel Placement -- 17 Tibial Bone Tunnel Placement in Double-Bundle Anterior Cruciate Ligament Reconstruction Using Hamstring Tendons -- 18 Tensioning and Fixation of the Graft -- 19 Tendon Regeneration after Harvest for ACL Reconstruction -- 20 Second-Look Arthroscopic Evaluation after ACL Reconstruction -- 21 Bone Tunnel Changes After ACL Reconstruction -- 22 Graft I impingement -- 23 Fixation Procedure -- Part V. Multiple bundle ACL Reconstruction -- 24 Single- vs. Double-Bundle ACL Reconstruction -- 25 Anatomic Double-Bundle Reconstruction Procedure -- 26 Triple-Bundle ACL Reconstruction with the Semitendinosus Tendon Graft -- Part VI. ACL Augmentation -- 27 History and Advantages of ACL Augmentation -- 28 Surgical Technique of ACL Augmentation -- Part VII. ACL Reconstruction Using Bone-Patella Tendon-Bone -- 29 An Overview -- 30 Anatomical Rectangular Tunnel ACL Reconstruction with a Bone-Patellar Tendon-Bone Graft -- 31 Rectangular vs. Round Tunnel -- Part VIII. Computer-Assisted Navigation in ACL Reconstruction -- 32 Intraoperative Biomechanical Evaluation Using a Navigation System -- 33 Application of Computer-Assisted Navigation -- Part IX. ACL Injury in Patients with Open Physes -- 34 ACL Reconstruction with Open Physes -- 35 Avulsion Fracture of the ACL -- Part X. Revision ACL Reconstruction -- 36 Double-Bundle Technique -- 37 Bone-Patellar Tendon-Bone Graft via Round Tunnel -- 38 Anatomical Revision ACL Reconstruction with Rectangular Tunnel Technique -- 39 One- vs. Two-Stage Revision Anterior Cruciate Ligament Reconstruction -- Part XI. Complications of ACL Reconstruction -- 40 Complications of ACL Reconstruction -- Part XII. Future of ACL Reconstruction -- 41 Future Challenges of Anterior Cruciate Ligament Reconstruction: Biological Modulation Using a Growth Factor Application for Enhancement of Graft Healing -- 42 Strategies to Enhance Biological Tendon-Bobe Healing in Anterior Cruciate Ligament Reconstruction -- 43 Tissue engineering approach for ACL healing.
- Format
- e-Book
- Location
- Online
Make Life Visible
https://libcat.nshealth.ca/en/permalink/provcat44715
Yoshiaki Toyama, Atsushi Miyawaki, Masaya Nakamura, Masahiro Jinzaki, editors.
--Singapore:
SpringerOpen
, c2020.
- Available Online
- View e-Book
- Access
- Open access
- Location
- Online
This open access book describes marked advances in imaging technology that have enabled the visualization of phenomena in ways formerly believed to be completely impossible. These technologies have made major contributions to the elucidation of the pathology of diseases as well as to their diagnosis and therapy. The volume presents various studies from molecular imaging to clinical imaging. It also focuses on innovative, creative, advanced research that gives full play to imaging technology in …
- Available Online
- View e-Book
- Other Authors
- Toyama, Yoshiaki
- Miyawaki, Atsushi
- Nakamura, Masaya
- Jinzaki, Masahiro
- Responsibility
- Yoshiaki Toyama, Atsushi Miyawaki, Masaya Nakamura, Masahiro Jinzaki, editors
- Place of Publication
- Singapore
- Publisher
- SpringerOpen
- Date of Publication
- c2020
- Physical Description
- 1 online resource (ix, 292 p.) : 137 illus., 106 illus. in color
- ISBN
- 9789811379086
- 9789811379079 (Print ed.)
- 9789811379093 (Print ed.)
- 9789811379109 (Print ed.)
- Subjects (MeSH)
- Biomedical Technology
- Clinical Laboratory Techniques
- Diagnostic Imaging - methods
- Image Processing, Computer-Assisted - methods
- Subjects (LCSH)
- Neurosciences
- Immunology
- Cell biology
- Specialty
- Diagnostic Imaging
- Abstract
- This open access book describes marked advances in imaging technology that have enabled the visualization of phenomena in ways formerly believed to be completely impossible. These technologies have made major contributions to the elucidation of the pathology of diseases as well as to their diagnosis and therapy. The volume presents various studies from molecular imaging to clinical imaging. It also focuses on innovative, creative, advanced research that gives full play to imaging technology in the broad sense, while exploring cross-disciplinary areas in which individual research fields interact and pursuing the development of new techniques where they fuse together. The book is separated into three parts, the first of which addresses the topic of visualizing and controlling molecules for life. Th e second part is devoted to imaging of disease mechanisms, while the final part comprises studies on the application of imaging technologies to diagnosis and therapy. The book contains the proceedings of the 12th Uehara International Symposium 2017, “Make Life Visible” sponsored by the Uehara Memorial Foundation and held from June 12 to 14, 2017. It is written by leading scientists in the field and is an open access publication under a CC BY 4.0 license.
- Contents
- Part 1: Visualizing and Controlling Molecules for Life -- 1. Photoacoustic Tomography: Deep Tissue Imaging by Ultrasonically Beating Optical Diffusion -- 2. Regulatory Mechanism of Neural Stem Cells Revealed by Optical Manipulation of Gene Expressions -- 3. Eavesdropping on Biological Processes with Multi-Dimensional Molecular Imaging -- 4. Apical microtubules define the function of epithelial cell sheets consisting of non-ciliated or multi-ciliated cells -- 5. Illuminating the brain -- 6. Optogenetic assemblies of cortical force-generating complexes during mitosis -- 7. In vivo Imaging Probes with Tunable Chemical Switches -- 8. Circuit-dependent striatal PKA and ERK signaling underlying action selection -- 9. Electrophysiology, Unplugged: New Chemical Tools to Image Voltage -- 10. Molecular dynamics revealed by single-molecule FRET measurement -- 11. Comprehensive approaches using luminescence to studies of cellular functions -- Part II: Imaging Disease Mechanisms -- 12. Make Chronic Pain Visible -- 13. Cortical plasticity after spinal cord injury using resting-state functional magnetic resonance imaging -- 14. Multimodal Label-free imaging to assess compositional and morphological changes in cells during immune activation -- 15. Investigating in vivo myocardial and coronary molecular pathophysiology in mice with X-ray radiation imaging approaches -- 16. Visualizing the Immune Response to Infections -- 17. Imaging Sleep and Wakefulness -- 18. Abnormal local translation in dendrites impairs cognitive functions in neuropsychiatric disorders -- 19. Imaging synapse formation and remodeling in vitro and in vivo -- Part III: Imaging-based Diagnosis and Therapy -- 20. How MRI makes the Brain Visible -- 21. Intravital multiphoton imaging revealing cellular dynamics in vivo -- 22. Theranostic Near Infrared Photoimmunotherapy for Cancer -- 23. Novel and integrated imaging on Chronic Fatigue -- 24. Novel fluorescent probes for rapid tumor imaging and fast glutathione dynamics -- 25. Coronary Heart Disease Diagnosis: Engineering Triumphs, Economic Barriers -- 26. Live imaging of the skin immune responses -- 27. Development of a horizontal CT and its application to musculoskeletal disease -- 28. The Future of Precision Health & Integrated Diagnostics -- 29. Imaging and therapy against hypoxic tumors with 64Cu-ATSM.
- Access
- Open access
- Format
- e-Book
- Location
- Online
Molecular Pathogenesis and Treatment of Chronic Myelogenous Leukemia
https://libcat.nshealth.ca/en/permalink/provcat40405
Masahiro Kizaki, editor.
(1st ed.)
--Tokyo:
Springer Japan
, c2016.
- Available Online
- View e-Book
- Location
- Online
Molecular Pathogenesis and Treatment of Chronic Myelogenous Leukemia provides a comprehensive understanding of the recent molecular genetics of Chronic Myelogenous Leukemia (CML) and a characterization of the molecular targets for drug development. Included are therapeutic implications, diagnosis, and prognosis for understanding and facilitating daily practice in the management of patients with CML. Understanding of the pathogenesis and therapy of hematological malignancies such as CML has grow…
- Available Online
- View e-Book
- Other Authors
- Kizaki, Masahiro
- Responsibility
- Masahiro Kizaki, editor
- Edition
- 1st ed.
- Place of Publication
- Tokyo
- Publisher
- Springer Japan
- Date of Publication
- c2016
- Physical Description
- 1 online resource (viii, 193 p. : 26 illus., 20 illus. in color)
- ISBN
- 9784431557142
- 9784431557135 (print ed.)
- Subjects (MeSH)
- Antineoplastic Agents - therapeutic use
- Leukemia, Myelogenous, Chronic, BCR-ABL Positive - drug therapy
- Leukemia, Myelogenous, Chronic, BCR-ABL Positive - genetics
- Leukemia, Myelogenous, Chronic, BCR-ABL Positive - pathology
- Protein Kinase Inhibitors - therapeutic use
- Abstract
- Molecular Pathogenesis and Treatment of Chronic Myelogenous Leukemia provides a comprehensive understanding of the recent molecular genetics of Chronic Myelogenous Leukemia (CML) and a characterization of the molecular targets for drug development. Included are therapeutic implications, diagnosis, and prognosis for understanding and facilitating daily practice in the management of patients with CML. Understanding of the pathogenesis and therapy of hematological malignancies such as CML has grown significantly in recent years. This development owe much to the progress in molecular biology and now makes a major contribution to diagnosis and to treatment that pharmacologically targets the molecular events of CML. Molecular targeting therapy with newly developed agents such as small molecules and antibodies for hematological malignancies are being discovered after years of research. Some of these, including tyrosine kinase inhibitors such as imatinib, nilotinib, and dasatinib, lead to increased survival rates and improved therapies. With the opinion leaders of basic and clinical research in the field as authors, this book reviews recent advances in the biology of CML.
- Contents
- 1. Identification and Biology of CML Stem Cells -- 2. Molecular Mechanisms of CML Stem Cell Maintenance -- 3. Roles for Signaling Molecules in the Growth and Survival of CML Cells -- 4. Goal of CML Treatment in the Tyrosine Kinase Inhibitor Era -- 5. Biomarkers for Determining the Prognosis of CML -- 6. Updated European LeukemiaNet Recommendations for the Management of CML -- 7. Optimal Monitoring of CML Treatment: Molecular and Mutation Analysis -- 8. Recommendations for Management of CML in the Era of Second-Generation TKIs -- 9. Role of New TKIs and Combinations with Interferon- for the Treatment of CML -- 10. Safety Profiles of First-Line TKIs and Managing Adverse Effects -- 11. Molecular Mechanism of TKI Resistance and Potential Approaches to Overcome Resistance -- 12. Discontinuation of Therapy and Treatment-Free Remission in CML.
- Format
- e-Book
- Location
- Online
Radiation Health Risk Sciences : Proceedings of the First International Symposium of the Nagasaki University Global COE Program "Global Strategic Center for Radiation Health Risk Control"
https://libcat.nshealth.ca/en/permalink/provcat29229
edited by Masahiro Nakashima, Noboru Takamura, Kunihiro Tsukasaki, Yuji Nagayama, Shunichi Yamashita.
--Tokyo:
Springer Japan
, c2009.
- Available Online
- View e-Book
- Location
- Online
- Available Online
- View e-Book
- Author
- Nakashima, Masahiro
- Other Authors
- Takamura, Noboru
- Tsukasaki, Kunihiro
- Nagayama, Yuji
- Yamashita, Shunichi
- Responsibility
- edited by Masahiro Nakashima, Noboru Takamura, Kunihiro Tsukasaki, Yuji Nagayama, Shunichi Yamashita
- Place of Publication
- Tokyo
- Publisher
- Springer Japan
- Date of Publication
- c2009
- ISBN
- 9784431886594
- Subjects (MeSH)
- Neoplasms, Radiation-Induced - Congresses
- Radiation Injuries - Congresses
- Radiation, Ionizing - Congresses
- Subjects (LCSH)
- Radiology, Medical
- Public health
- Format
- e-Book
- Location
- Online
Testicular Autoimmunity : A Cause of Male Infertility
https://libcat.nshealth.ca/en/permalink/provcat41911
Masahiro Itoh.
--Tokyo:
Springer
, 2017.
- Available Online
- View e-Book
- Location
- Online
This book addresses various aspects of testicular autoimmunity. It has long been suspected that testicular autoimmunity could be one of the causes of idiopathic male infertility. However, it is very difficult to estimate the incidence of testicular autoimmunity in men, as most male patients first realize they are infertile when they start trying to conceive a child, and there is a possibility that their testes may already exhibit the end stage of testicular autoimmunity, in which lymphocytic in…
- Available Online
- View e-Book
- Author
- Itoh, Masahiro
- Responsibility
- Masahiro Itoh
- Place of Publication
- Tokyo
- Publisher
- Springer
- Date of Publication
- 2017
- Physical Description
- 1 online resource (xvii, 232 pages) : 54 illus., 43 illus. in color
- ISBN
- 9784431544609
- 9784431544593 (print ed.)
- Subjects (MeSH)
- Autoimmunity
- Disease Models, Animal
- Infertility, Male - etiology
- Testis - immunology
- Abstract
- This book addresses various aspects of testicular autoimmunity. It has long been suspected that testicular autoimmunity could be one of the causes of idiopathic male infertility. However, it is very difficult to estimate the incidence of testicular autoimmunity in men, as most male patients first realize they are infertile when they start trying to conceive a child, and there is a possibility that their testes may already exhibit the end stage of testicular autoimmunity, in which lymphocytic inflammation and immunoglobulin deposition in their testes subsided long ago and only the spermatogenic disorder remains. Therefore, autopsy or biopsy for testicular tissues in men before the end stage of testicular autoimmunity and investigations using testicular autoimmunity model animals are needed to determine the epidemiology of testicular autoimmunity. Accordingly, the book discusses "the immunological fragility of testis" with regard to male infertility, reviewing aut opsy data in men and presenting experimental data using murine models of autoimmune orchitis that has been induced by immunizing with viable syngeneic testicular germ cells alone. Testicular autoimmunity in animals is also discussed. In summary, the book provides a wealth of valuable information, not only for researchers who are interested in immunologic male infertility, but also for clinical professionals who treat these patients at hospitals.
- Contents
- 1. Biological Background of Testicular Autoimmunity -- 2. Microcircumstance for Induction and Prevention of Testicular Autoimmunity -- 3. Human Testicular Autoimmunity as a Result of Breakdown of Testicular Immune Privilege -- 4. Testicular Autoimmunity by Immunization with Testicular Antigens Alone in Experimental Animals -- 5. Testicular Autoimmunity by the Systemic Treatment with Immuno-Potentiating Agents in Experimental Animals -- 6. Testicular Autoimmunity by Local Injury of the Testis in Experimental Animals -- 7. Testicular Autoimmunity by Alteration of the Immune System in Experimental Animals -- 8. The Future Directions of Testicular Autoimmunity Investigation.
- Format
- e-Book
- Location
- Online
