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Role of Capsaicin in Oxidative Stress and Cancer

https://libcat.nshealth.ca/en/permalink/provcat32646
Sanjay K. Srivastava, editor. --Dordrecht: Springer , c2013.
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Capsaicin is a principal pungent ingredient of red chili peppers, first isolated in the early nineteenth century by Christian Friedrich Bucholz. Widely consumed as a spice in South Asia and Latin America, Capsaicin has been used to treat pain and inflammation associated with a variety of diseases, including rheumatoid arthritis, diabetic neuropathy, post-masectomy pain, cluster headaches, and herpes zoster. Although recent studies have evaluated capsaicin as a novel anti-cancer agent, and mecha…
Available Online
View e-Book
Other Authors
Srivastava, Sanjay K
Responsibility
Sanjay K. Srivastava, editor
Place of Publication
Dordrecht
Publisher
Springer
Date of Publication
c2013
Physical Description
1 online resource (ix, 178 p. : 27 ill., 9 ill. in color)
Series Title
Diet and cancer
ISBN
9789400763173
Subjects (MeSH)
Capsaicin - pharmacology
Capsaicin - therapeutic use
Subjects (LCSH)
Medicine
Science (General)
Oncology
Gene expression
Toxicology
Cytology
Abstract
Capsaicin is a principal pungent ingredient of red chili peppers, first isolated in the early nineteenth century by Christian Friedrich Bucholz. Widely consumed as a spice in South Asia and Latin America, Capsaicin has been used to treat pain and inflammation associated with a variety of diseases, including rheumatoid arthritis, diabetic neuropathy, post-masectomy pain, cluster headaches, and herpes zoster. Although recent studies have evaluated capsaicin as a novel anti-cancer agent, and mechanisms of capsaicin in preventing cancer have been described sporadically, the literature lacks a comprehensive review of capsaicin as a chemo-preventive agent. Role of Capsaicin in Oxidative Stress and Cancer offers a thorough exploration of the preventive and therapeutic effects of capsaicin in cancer models such as melanoma, pancreatic cancer, colon cancer, gastric cancer, breast cancer, prostate cancer, skin cancer, lung cancer, multiple myeloma and glioma. The contributors, all internationally recognized researchers, identify various molecular and cellular targets of capsaicin, and show the critical role of mitochondria in capsaicin-mediated therapeutic effects. Readers will learn how capsaicin prevents or may treat cancer, how different cells respond to capsaicin, how environmental carcinogen-induced carcinogenesis can be prevented by capsaicin and the mechanism of oxidative stress caused by capsaicin. This book will benefit medical students, oncologists and cancer researchers everywhere.
Format
e-Book
Location
Online
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