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Understanding Hughes Syndrome : Case Studies for Patients

https://libcat.nshealth.ca/en/permalink/provcat40948
Graham R. V. Hughes. --London: Springer , c2009.
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Antiphospholipid Syndrome or Hughes Syndrome was the major medical discovery of the late 20th century; for many it is still deemed a new disease. As a result many people are now living with the disease with little knowledge of its causes, effects and available treatments. Many of these patients are also struggling to cope with the daily demands posed by living with such an illness. Understanding Hughes Syndrome: Case Studies for Patients, presents 50 case histories, each covered independently t…
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Author
Hughes, Graham R. V
Responsibility
Graham R. V. Hughes
Place of Publication
London
Publisher
Springer
Date of Publication
c2009
Physical Description
1 online resource (xiv, 94 p.)
ISBN
9781848003767
9781848009325 (print ed.)
Subjects (MeSH)
Antiphospholipid Syndrome
Abstract
Antiphospholipid Syndrome or Hughes Syndrome was the major medical discovery of the late 20th century; for many it is still deemed a new disease. As a result many people are now living with the disease with little knowledge of its causes, effects and available treatments. Many of these patients are also struggling to cope with the daily demands posed by living with such an illness. Understanding Hughes Syndrome: Case Studies for Patients, presents 50 case histories, each covered independently to give a comprehensive view of the vast spectrum that is Antiphospholipid Syndrome. Neurological aspects and effects are covered in approximately half the text, with the remainder covering everything from repeated miscarriages to easy bruising. The provision of personal accounts of Antiphospholipid Syndrome makes this book the ultimate companion to people living with the disease; giving not only the facts but also the personal touch that many people need when coming to terms, and dealing, with their condition. Understanding Hughes Syndrome: case studies for patients is written by Graham R.V. Hughes, MD, FRCP, a world-renowned expert in the field of rheumatology, and as the name suggests discoverer of Hughes or Antiphospholipid Syndrome. Hughes is also the Head of The London Lupus Centre, Founder and Editor of the international journal Lupus, and life president of the lupus patients charity Lupus UK.
Contents
The Brain -- Late for the Wedding -- Falling Over -- Diplomatic Epilepsy -- Weak Legs -- Multiple Sclerosis -- Teenage Migraine -- Getting Only Half the Picture -- Difficult Crossword Puzzles -- Playing the Wrong Notes -- Speaking Gibberish -- I Lost My Sense of Smell -- Movement, Jerks and Twitches -- Mad Cow Disease -- St. Vitus Dance -- Parkinson's Disease -- Missing the Target -- The Headmistress Who Forgot -- "Personality Disorder" in a 4-Year-Old -- To Sleep... Perchance to Dream -- ... and Other Organs -- Collapse at the Airport -- Ballerina's Leg Ulcers -- Twenty Years On -- "Heart Attack" -- Backpacking in Australia -- Short of Breath in Scandinavia -- Easy Bruising -- Addison's Disease: 200 Years On? -- Tummy Pain -- Impotence -- Severe Leg Pain -- Pain in the Foot (Toelitis) -- The Bells Are Ringing -- The Swollen Legs -- The Computer has Crashed (The Catastrophic APS) -- Pregnancy, Miscarriage, Infertility -- Eleven Miscarriages -- Late Pregnancy Tragedy -- The Infertility Clinic -- Causes and Effects -- The Pill and I -- A Bad Back -- A Miracle -- Climbing the Andes -- Fear of Flying -- The Lambeth Walk -- The Tests are Negative! -- Aspects of Treatment -- "My Sister has Hughes Syndrome" -- Trial and Error -- "I Saved the Country Ð73,000" -- What Happened Next? -- "Your Condition Doesn't Exist" -- "I've Got My Life Back!".
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e-Book
Publication Type
Case Reports
Popular Works
Location
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Hughes Syndrome : Highways and Byways

https://libcat.nshealth.ca/en/permalink/provcat40708
Graham Hughes, Munther A Khamashta. --London: Springer , c2013.
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Hughes Syndrome: Highways and Byways is a handy and easy-to-read guide to the main features of Hughes syndrome. There has been worldwide interest in this 'new' syndrome (first described in 1983). A clotting tendency which can potentially affect any organ in the body, it is: responsible for 1 in 5 recurrent miscarriages (now successfully treated with aspirin and heparin); responsible for 1 in 5 young (under 45) strokes; a major cause of early heart attacks; responsible for 1 in 5 deep vein throm…
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Author
Hughes, Graham
Other Authors
Khamashta, Munther A
Responsibility
Graham Hughes, Munther A Khamashta
Place of Publication
London
Publisher
Springer
Date of Publication
c2013
Physical Description
1 online resource (x, 94 p. : 15 illus., 14 illus. in color)
ISBN
9781447151616
9781447151609 (print ed.)
Subjects (MeSH)
Antiphospholipid Syndrome
Abstract
Hughes Syndrome: Highways and Byways is a handy and easy-to-read guide to the main features of Hughes syndrome. There has been worldwide interest in this 'new' syndrome (first described in 1983). A clotting tendency which can potentially affect any organ in the body, it is: responsible for 1 in 5 recurrent miscarriages (now successfully treated with aspirin and heparin); responsible for 1 in 5 young (under 45) strokes; a major cause of early heart attacks; responsible for 1 in 5 deep vein thromboses; an important cause of migraine. Hughes Syndrome: Highways and Byways is a valuable resource for professionals with an interest in the subject, as well as general practitioners and patients.
Format
e-Book
Location
Online
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The coagulation consult : a case-based guide

https://libcat.nshealth.ca/en/permalink/provcat33434
Alan Lichtin, John Bartholomew, editors. --New York: Springer , c2014.
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There have been many changes in the field of coagulation during the past decade. New concepts of epidemiology of risk factors for thrombosis now help clinicians predict who is more likely to form clots after surgery, or after being placed on oral contraceptives. New anticoagulants have the potential to redefine how patients with atrial fibrillation and venous thrombosis are managed. There are new forms of recombinant clotting factors which have changed our approach to hypofibrinogenemia and von…
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Other Authors
Lichtin, Alan
Bartholomew, John R
Responsibility
Alan Lichtin, John Bartholomew, editors
Place of Publication
New York
Publisher
Springer
Date of Publication
c2014
Physical Description
1 online resource (xii, 279 pages)
ISBN
9781461495604 (electronic bk.)
9781461495598
Subjects (MeSH)
Blood Coagulation Disorders - diagnosis
Blood Coagulation Disorders - therapy
Subjects (LCSH)
Blood coagulation disorders
Blood - Coagulation
Hematology
Oncology
Abstract
There have been many changes in the field of coagulation during the past decade. New concepts of epidemiology of risk factors for thrombosis now help clinicians predict who is more likely to form clots after surgery, or after being placed on oral contraceptives. New anticoagulants have the potential to redefine how patients with atrial fibrillation and venous thrombosis are managed. There are new forms of recombinant clotting factors which have changed our approach to hypofibrinogenemia and von Willebrand's disease. Newer antiplatelet agents are available and their use in patients receiving cardiac stents has mushroomed. The management of thrombosis in the setting of pregnancy has changed over the past decade, as well as the way clinicians approach women with multiple miscarriages. An entire new class of compounds, the thrombopoietins, are available to treat individuals with immune thrombocytopenic purpura (ITP). The Coagulation Consult covers major topics of interest to hematologists who are asked to consult on individuals with coagulation related diseases, and encompasses the field's most recent developments. This "case-directed" book describes state-of-the-art approaches to patients with bleeding and clotting disorders, as well as laboratory tests for coagulation. Chapters include different vignettes, focus on typical clinical consult questions, and lay out specific types of treatment. Practicing clinicians being confronted with a coagulation consult, students, residents, fellows and attending physicians will find this unique text an invaluable resource for some of the newer areas of coagulation science, therapy and pharmacology.
Contents
1. Laboratory Analysis of Coagulation -- 2. Easy Bruisability -- 3. Prolonged PT -- 4. Prolonged PTT -- 5. Prolongation of Both PT and aPTT -- 6. Excessive Bleeding with Normal Prothrombin Time, Partial Thromboplastin Time, and Platelet Count -- 7. Diagnosing Thrombocytopenia in the Clinic -- 8. Thrombocytopenia in the Intensive Care Unit and after Solid Organ Transplantation -- 9. Thrombocytosis -- 10. Prolonged Bleeding after Surgery -- 11. The Excessively Clotting Cancer Patient -- 12. Thrombotic Risk factors -- 13. Clotting around Catheters and Other Devices -- 14. Heparin-Induced Thrombocytopenia -- 15. Surgery on Patients on Antiplatelet Agents -- 16. Newer Oral Anticoagulants -- 17. Pregnancy.
Format
e-Book
Location
Online
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Stroke Medicine : Case Studies from Queen Square

https://libcat.nshealth.ca/en/permalink/provcat38911
S.K. Gill, M.M. Brown, F. Robertson, N. Losseff, editors. --London: Springer , c2015.
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This collection of case studies is authored by a group of internationally recognised experts in the field of cerebrovascular disease. The cases are carefully selected to provide an insight into the different kinds of stroke syndromes from the common through to more rare presentations of cerebrovascular pathology. Each case is worked through with a discussion on presentation, clinical features, examination, radiological findings and management. Finally, learning points are highlighted to help th…
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Other Authors
Gill, S.K. (Sumanjit K.)
Responsibility
S.K. Gill, M.M. Brown, F. Robertson, N. Losseff, editors
Place of Publication
London
Publisher
Springer
Date of Publication
c2015
Physical Description
1 online resource (xvi, 270 p.) : 88 illus., 18 illus. in color
ISBN
9781447167051
9781447167044 (print ed.)
Subjects (MeSH)
Stroke
Other Subjects
United Kingdom
Abstract
This collection of case studies is authored by a group of internationally recognised experts in the field of cerebrovascular disease. The cases are carefully selected to provide an insight into the different kinds of stroke syndromes from the common through to more rare presentations of cerebrovascular pathology. Each case is worked through with a discussion on presentation, clinical features, examination, radiological findings and management. Finally, learning points are highlighted to help the reader focus on the key points of the case study. Stroke Medicine: Case Studies from Queen Square is aimed at medical students and doctors in all stages of training from foundation years through to consultancy.
Contents
A Rapidly Progressive Dementia -- A Headache after Starting the Oral Contraceptive Pill -- A Child with Enlarged Pupils -- Locked in or Break Out?- An Unusual TIA -- Hemianopic Alexia -- Recurrent Miscarriages and Neurological Symptoms -- A Pain in the Neck -- A Painless Loss of Vision -- Sickle Cell Disease and Stroke -- A New Mother with Rapidly Developing Blindness -- A Potentially Fatal Complication -- A Funny Turn in the Toilet -- A Strategic Infarct Leading to Mild Cognitive Impairment -- A Misbehaving Limb -- More than Just A Sore Throat -- An MRI Saves a Patient from Unnecessary Surgery -- Confusion after the Flu -- One Night with Venus, a Lifetime with Mars -- A Hypertensive Spike -- Lying in Wait: Stroke and a Blistering Rash -- An Unusual Case of Paradoxical Embolus -- Reaching a Crescendo -- Bihemispheric Infarcts -- Sleep Disordered Breathing and Stroke -- A Possible Remedy for Post Stroke Confusion -- A Headache with a Difference -- An Alternative Solution to a Difficult Problem -- Botox Saves the Day -- A Diagnosis not to Forget -- A Migraine with Persistent Focal Symptoms -- Stroke and Systemic Disease -- An Unusual Hypertensive Headache -- Recurrent Thunderclap Headaches -- Stroke in Pregnancy -- Cortical Blindness -- Cerebrovascular Disease in Childhood -- Recurrent Neurological Symptoms Mistaken as Multiple Sclerosis -- Intracerebral Haemorrhage and Oral Anticoagulants -- Choked in the Night.
Format
e-Book
Publication Type
Case Reports
Location
Online
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Antiphospholipid Syndrome : Current Research Highlights and Clinical Insights

https://libcat.nshealth.ca/en/permalink/provcat41773
Doruk Erkan, Michael D. Lockshin, editors. --Cham: Springer , 2017.
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This new edition is a comprehensive and updated resource on antiphospholipid syndrome (APS), which is an autoimmune disorder. In APS, the body recognizes certain normal components of blood and/or cell membranes as foreign substances and produces antibodies (antiphospholipid antibodies) against them. APS is associated with recurrent clotting events (thrombosis) including premature stroke, repeated miscarriages, phlebitis, venous thrombosis, and pulmonary thromboembolism. It is also associated wi…
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Other Authors
Erkan, Doruk
Lockshin, Michael D
Responsibility
Doruk Erkan, Michael D. Lockshin, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
2017
Physical Description
1 online resource (xx, 372 pages) : 18 illus., 16 illus. in color
ISBN
9783319554426
9783319554402 (print ed.)
Subjects (MeSH)
Antiphospholipid Syndrome
Abstract
This new edition is a comprehensive and updated resource on antiphospholipid syndrome (APS), which is an autoimmune disorder. In APS, the body recognizes certain normal components of blood and/or cell membranes as foreign substances and produces antibodies (antiphospholipid antibodies) against them. APS is associated with recurrent clotting events (thrombosis) including premature stroke, repeated miscarriages, phlebitis, venous thrombosis, and pulmonary thromboembolism. It is also associated with low platelet or blood elements that prevent bleeding. Recently, however, even more disease states have been linked with APS, including premature heart attack, various cardiac valvular abnormalities, skin lesions, kidney disease, abnormal involuntary movement/chorea, diseases that mimic multiple sclerosis, and vascular diseases of the eye that can lead to visual loss and blindness. The International Congress on Antiphospholipid Antibodies, held every 3 years, is the venue where representatives from different disciplines gather to discuss the recent advances in APS. The conference intends to cover basic aspects of APS, such as pathogenesis, origins, genetics, intracellular and molecular events, the role of infections, as well as traditional and non-traditional clinical manifestations associated with antiphospholipid antibodies. The 15th Congress took place in September 2016. A novel aspect of the Congress was that multiple teams, chaired by Scientific Planning Committee members, used evidence-based literature reviews and expert discussions to answer specific pre-defined APS-related questions. These teams included points of view from experts in rheumatology, hematology, cardiovascular medicine, obstetrics, neurology, and immunology. The Scientific Planning Committee members also chaired the congress sessions and supervised completion of the reports that are the bases of the chapters of this book. In addition, there are two chapters included specifically written for APS patients. Much like the previous volume, dedicated to the 13th International Congress on Antiphospholipid Antibodies (April 2010), this up-to-date and comprehensive work gathers invaluable insights from a multidisciplinary team of world-renowned experts and represents the authoritative resource on causes, symptoms, diagnosis, and treatment of APS.
Contents
Part I: HISTORICAL ASPECTS OF ANTIPHOSPHOLIPID SYNDROME -- History of Antiphospholipid Antibody -- Part II. BASIC SCIENCE ASPECTS OF ANTIPHOSPHOLIPID SYNDROME -- Natural Proteins Involved in Antiphospholipid Syndrome -- Origin of Antiphospholipid Antibodies -- Recent Advances in Understanding of the Genetics of Antiphospholipid Syndrome -- Mechanisms of Antiphospholipid Antibody-mediated Thrombosis -- Mechanisms of Antiphospholipid Antibody-mediated Pregnancy Morbidity -- Definition and Epidemiology of Antiphospholipid Syndrome -- Part III. CLINICAL & DIAGNOSTIC ASPECTS OF ANTIPHOSPHOLIPID SYNDROME -- Clinical and Prognostic Significance of Non-criteria Antiphospholipid Antibody Tests -- Disease and Risk Measurement Criteria in Antiphospholipid Syndrome -- Neuropsychiatric Manifestations of Antiphospholipid Syndrome -- Part IV. THERAPEUTIC ASPECTS OF ANTIPHOSPHOLIPID SYNDROME -- Prevention and Treatment of Thrombotic Antiphospholipid Syndrome -- Prevention and Treatment of Obstetric Antiphospholipid Syndrome -- Treatment of Non-criteria Manifestations in Antiphospholipid Syndrome -- Antiphospholipid Syndrome Alliance for Clinical Trials and InternatiOnal Networking (APS ACTION) -- Part V. 15th INTERNATIONAL CONGRESS ON ANTIPHOSPHOLIPID ANTIBODIES TASK FORCE REPORTS -- 15th International Congress on Antiphospholipid Antibodies - Task Force on Antiphospholipid Syndrome Classification Criteria Report -- 15th International Congress on Antiphospholipid Antibodies - Task Force on Pediatric Antiphospholipid Syndrome Report -- 15th International Congress on Antiphospholipid Antibodies - Task Force on Catastrophic Antiphospholipid Syndrome Report -- Part VI. ANTIPHOSPHOLIPID SYNDROMR FOR PATIENTS -- Antiphospholipid Syndrome: What Should Patients Know? -- Obstetric Antiphospholipid Syndrome: What Should Patients Know?
Format
e-Book
Location
Online
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