Antiphospholipid Syndrome or Hughes Syndrome was the major medical discovery of the late 20th century; for many it is still deemed a new disease. As a result many people are now living with the disease with little knowledge of its causes, effects and available treatments. Many of these patients are also struggling to cope with the daily demands posed by living with such an illness. Understanding Hughes Syndrome: Case Studies for Patients, presents 50 case histories, each covered independently t…
Hughes Syndrome: Highways and Byways is a handy and easy-to-read guide to the main features of Hughes syndrome. There has been worldwide interest in this 'new' syndrome (first described in 1983). A clotting tendency which can potentially affect any organ in the body, it is: responsible for 1 in 5 recurrent miscarriages (now successfully treated with aspirin and heparin); responsible for 1 in 5 young (under 45) strokes; a major cause of early heart attacks; responsible for 1 in 5 deep vein throm…
There have been many changes in the field of coagulation during the past decade. New concepts of epidemiology of risk factors for thrombosis now help clinicians predict who is more likely to form clots after surgery, or after being placed on oral contraceptives. New anticoagulants have the potential to redefine how patients with atrial fibrillation and venous thrombosis are managed. There are new forms of recombinant clotting factors which have changed our approach to hypofibrinogenemia and von…
This collection of case studies is authored by a group of internationally recognised experts in the field of cerebrovascular disease. The cases are carefully selected to provide an insight into the different kinds of stroke syndromes from the common through to more rare presentations of cerebrovascular pathology. Each case is worked through with a discussion on presentation, clinical features, examination, radiological findings and management. Finally, learning points are highlighted to help th…
This new edition is a comprehensive and updated resource on antiphospholipid syndrome (APS), which is an autoimmune disorder. In APS, the body recognizes certain normal components of blood and/or cell membranes as foreign substances and produces antibodies (antiphospholipid antibodies) against them. APS is associated with recurrent clotting events (thrombosis) including premature stroke, repeated miscarriages, phlebitis, venous thrombosis, and pulmonary thromboembolism. It is also associated wi…