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Autonomic Nervous System : Basic and Clinical Aspects

https://libcat.nshealth.ca/en/permalink/provcat43421
Daniel Pedro Cardinali. --Cham: Springer , c2018.
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A traditional view of the Autonomic Nervous System (ANS) considers only its peripheral part: the sympathetic and parasympathetic systems. However, this view misses to consider the most important ANS function: the maintenance of homeostasis. This term is used today to define not only the strategies that allow the body proper response to changes in the environment (reactive homeostasis), but also temporal mechanisms that allow the body to predict the most likely timing of environmental stimuli (p…
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Author
Cardinali, Daniel Pedro
Responsibility
Daniel Pedro Cardinali
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2018
Physical Description
1 online resource (xiv, 385 p.) : 198 illus. in color
ISBN
9783319575711
9783319575704 (print ed.)
9783319575728 (print ed.)
9783319861975 (print ed.)
Subjects (MeSH)
Autonomic Nervous System
Specialty
Neurology
Abstract
A traditional view of the Autonomic Nervous System (ANS) considers only its peripheral part: the sympathetic and parasympathetic systems. However, this view misses to consider the most important ANS function: the maintenance of homeostasis. This term is used today to define not only the strategies that allow the body proper response to changes in the environment (reactive homeostasis), but also temporal mechanisms that allow the body to predict the most likely timing of environmental stimuli (predictive homeostasis based on biological rhythms). This book discusses the ANS from both an enlarged and a timed perspective. First, it presents how the organization of the ANS is hierarchical into different levels. Following that, the book discusses how the ANS changes functionally in the three-body configurations (wakefulness, slow sleep, rapid eye movement sleep) found in a 24-hour cycle. Finally, the most important clinical implications of this enlarged and timed vision of ANS will be discussed. Autonomic Nervous System: Basic and Clinical Aspects is a comprehensive text intended for medical students and health professionals who are interested in a deeper approach to this important part of the nervous system. It provides a detailed and complete understanding of the neuroscience behind the ANS, allowing a proper clinical applicability of this knowledge.
Contents
Introduction -- The enlarged Autonomic Nervous System -- The timed Autonomic Nervous System -- First level: Peripheral sympathetic and parasympathetic nervous system -- Second level: The brainstem -- Third level: The hypothalamus -- Fourth level: The limbic system -- Clinical implications of the enlarged Autonomic Nervous System -- Clinical implications of the timed Autonomic Nervous System.
Format
e-Book
Location
Online
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Ma Vie en Noir : Fifty Years with Melatonin and the Stone of Madness

https://libcat.nshealth.ca/en/permalink/provcat40301
Daniel Pedro Cardinali. --Cham: Springer , c2016.
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I wrote this book urged by the overwhelming desire that arises towards the end of life to recapitulate the past. My goal was to summarize my experience of practicing science at the end of the 20th and early 21st centuries in Argentina, a country located far away from the world's leading scientific centers. In the book, I summarize the intricacies of the pineal gland ("the stone of madness") as historical, mystical and medical entity and its entry in contemporary medicine with the description of…
Available Online
View e-Book
Author
Cardinali, Daniel Pedro
Responsibility
Daniel Pedro Cardinali
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2016
Physical Description
1 online resource (xiii, 301 p. : 119 illus., 91 illus. in color)
Series Title
Springer Biographies
ISBN
9783319416793
9783319416786 (print ed.)
Subjects (MeSH)
Chronobiology Discipline - history
Chronobiology Phenomena
Chronotherapy
Melatonin - history
Melatonin - therapeutic use
Mental Disorders - history
Pineal Gland - physiology
Abstract
I wrote this book urged by the overwhelming desire that arises towards the end of life to recapitulate the past. My goal was to summarize my experience of practicing science at the end of the 20th and early 21st centuries in Argentina, a country located far away from the world's leading scientific centers. In the book, I summarize the intricacies of the pineal gland ("the stone of madness") as historical, mystical and medical entity and its entry in contemporary medicine with the description of melatonin. I also reflect on how being associated with an unexplored subject at the beginning of their scientific career impacts the life of a scientist throughout their entire life. Today we know that in humans pineal melatonin begins is released every day late in the evening, and there is evidence that it is the trigger for the sleep process. But the most exciting aspect of melatonin is that it is a substance that is present in all living creatures, from unicellular organisms to plants and higher mammals, a fact that evinces its importance for life. Further, the neuroprotective action of melatonin promises to be crucial for the control of neurodegenerative diseases we face as a pandemic in this century. The discoverer of melatonin, Aaron Lerner, based its name on melano, the Greek word for black, because of its effect on the pigment cells of the skin. As in "La vie en rose", the immortal Edith Piaf song written in 1946, my lifelong work with melatonin could well be called "Ma vie en noir".
Contents
1. Brief History of the Stone of Madness -- 2. The Prescientific Stage of the Pineal Gland -- 3. The Beginnings of the Pineal Scientific Era: From the Late Nineteenth Century to Melatonin’s Discovery -- 4. Sleep/Wake Cycle: History and Facts -- 5. When This Chronicler Enters the Story: The 1960s -- 6. The Stone of Madness as a Neuroendocrine Organ and Model: The 1970s -- 7. Peripheral Innervation of Neuroendocrine-Immune System: The Challenges to Change a Physiological Paradigm -- 8. Melatonin as a Potential Therapeutic Agent: The 1980s -- 9. Melatonin as a Chronobiotic That Opens the “Gates of Sleep”: The 1990s -- 10. Melatonin and the “Diseases of the Soul”: The Stone of Madness Returns -- 11. Twenty-First Century: The 24/7 Society as an Environmental Mutation -- 12. Melatonin as a Medicament for the 24/7 Society: Metabolic Syndrome -- 13. Melatonin as a Medicament for the 24/7 Society: Normal and Pathological Aging -- 14. Melatonin as a Medicament for the 24/7 Society: Cancer -- 15. Melatonin as a Nutraceutical -- Epilogue.
Format
e-Book
Location
Online
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