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The heart and circulation : an integrative model

https://libcat.nshealth.ca/en/permalink/provcat33285
Branko Furst. --London: Springer , c2014.
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What drives the circulation? In this comprehensive review of existing circulation models, the conventional view that the heart is a pressure-propulsion pump is challenged. The existing models fail to explain an increasing number of observed circulatory phenomena. A unifying circulation model is proposed in which the blood, responding to metabolic demands of the tissues, is the primary regulator of cardiac output. This new model arises from accumulated clinical and experimental evidence. The hea…
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Author
Furst, Branko
Responsibility
Branko Furst
Place of Publication
London
Publisher
Springer
Date of Publication
c2014
Physical Description
1 online resource (xxix, 226 pages)
ISBN
9781447152774 (electronic bk.)
9781447152767
Subjects (MeSH)
Blood Circulation - physiology
Cardiovascular System - embryology
Heart - physiology
Hemodynamics - physiology
Myocardium
Subjects (LCSH)
Hemodynamics
Blood Circulation
Blood - Circulation
Cardiology
Abstract
What drives the circulation? In this comprehensive review of existing circulation models, the conventional view that the heart is a pressure-propulsion pump is challenged. The existing models fail to explain an increasing number of observed circulatory phenomena. A unifying circulation model is proposed in which the blood, responding to metabolic demands of the tissues, is the primary regulator of cardiac output. This new model arises from accumulated clinical and experimental evidence. The heart, rather than being an organ of blood propulsion, assumes a secondary role and generates pressure by impeding the flow of blood. This is supported by examples from the fields of early embryonic circulation, comparative phylogeny, functional morphology, exercise physiology and a range of clinical scenarios. The Heart and Circulation: An Integrative Model offers a paradigm shift in the understanding of circulatory phenomena. It will become a valuable resource for all those clinicians, researchers, educators and students who, having been confronted with the paradox of the circulation, are looking for a broader interpretation.
Contents
Part I. Embryonic Circulation -- Early Embryo Circulation -- The Onset of Circulation -- Hemodynamics of the Early Embryo Circulation -- Flow Patterns in the Early Embryo Circulation -- Is There a Circulation Without a Heart? -- Embryo Heart is not a Peristaltic Pump -- Flow Perturbation Experiments -- Heart Rate Perturbations -- The Heart as Generator of Pressure -- Ventriculo-Vascular Interaction -- A Brief Comparative Phylogeny -- Evolutionary Aspect of the Rhythmical System -- Part II. Mature Circulation -- Functional Morphology of the Heart -- Regulation of Cardiac Output -- Circulatory and Respiratory Functions of the Blood -- Models of the Heart -- Cardiovascular Response during Exercise -- Hemodynamic Effects of Aortic Occlusion -- Increased Pulmonary Flows -- Single Ventricle Physiology -- Blood as an Organ.
Format
e-Book
Location
Online
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The Heart and Circulation : An Integrative Model

https://libcat.nshealth.ca/en/permalink/provcat45053
Branko Furst. (Second edition) --Cham: Springer , c2020.
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Location
Online
This extensively revised second edition traces the development of the basic concepts in cardiovascular physiology in light of the accumulated experimental and clinical evidence. It considers the early embryonic circulation, where blood circulation suggests the existence of a motive force, tightly coupled to the metabolic demands of the tissues. It proposes that rather than being an organ of propulsion, the heart, serves as an organ of control, generating pressure by rhythmically impeding blood …
Available Online
View e-Book
Author
Furst, Branko
Responsibility
Branko Furst
Edition
Second edition
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2020
Physical Description
1 online resource (xl, 376 p.) : 136 illus., 105 illus. in color
ISBN
9783030250621
9783030250614 (Print ed.)
9783030250638 (Print ed.)
9783030250645 (Print ed.)
Subjects (MeSH)
Blood Circulation - physiology
Cardiovascular System - embryology
Heart - physiology
Hemodynamics - physiology
Myocardium
Specialty
Cardiology
Abstract
This extensively revised second edition traces the development of the basic concepts in cardiovascular physiology in light of the accumulated experimental and clinical evidence. It considers the early embryonic circulation, where blood circulation suggests the existence of a motive force, tightly coupled to the metabolic demands of the tissues. It proposes that rather than being an organ of propulsion, the heart, serves as an organ of control, generating pressure by rhythmically impeding blood flow. New and expanded chapters cover the arterial pulse, circulation in the upright posture, microcirculation and functional heart morphology. Heart and Circulation offers a new perspective for deeper understanding of the human cardiovascular system. It is therefore a thought-provoking resource for cardiologists, cardiac surgeons and trainees interested in models of human circulation.
Contents
Part I. Embryonic Circulation -- 1. Early Embryo Circulation -- 2. The Onset of Circulation -- 3. Hemodynamics of the Early Embryo Circulation -- 4. Flow Patterns in the Early Embryo Circulation -- 5. Is There a Circulation Without a Heart? -- 6. The Embryo Heart is Not a Peristaltic Pump -- 7. Flow Perturbation Experiments -- 8. Heart Rate Perturbations -- 9. The Heart as a Generator of Pressure -- 10. Ventriculo–Vascular Interaction -- 11. A Brief Comparative Phylogeny -- 12. Evolutionary Aspect of the Rhythmical System -- Part II. Mature Circulation -- 13. Functional Morphology of the Heart -- 14. Regulation of Cardiac Output -- 15. Circulatory and Respiratory Functions of the Blood -- 16. Models of the Heart -- 17. Cardiovascular Response During Exercise -- 18. Hemodynamic Effects of Aortic Occlusion -- 19. Increased Pulmonary Flows -- 20. Single Ventricle Physiology -- 21. Microcirculation -- Part III. Human Circulation -- 22. Arterial Pulse -- 23. Heartbeat and Respiration: Toward a Functional Chronobiology -- 24. The Effect of Gravity and Upright Posture on Circulation -- 25. The Integrative Model of Circulation: A Synthesis.
Format
e-Book
Location
Online
Less detail