Handbook of psycholinguistics
https://libcat.nshealth.ca/en/permalink/provcat27196
edited by Matthew J. Traxler, Morton A. Gernsbacher.
(2nd ed.)
--Amsterdam, Netherlands:
Elsevier
, 2006.
- Available Online
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- Location
- Online
- Available Online
- View e-Book
- Author
- Traxler, Matthew J
- Other Authors
- Gernsbacher, Morton Ann
- Responsibility
- edited by Matthew J. Traxler, Morton A. Gernsbacher
- Edition
- 2nd ed.
- Place of Publication
- Amsterdam, Netherlands
- Publisher
- Elsevier
- Date of Publication
- 2006
- ISBN
- 6610728909 (electronic bk.)
- Subjects (MeSH)
- Psycholinguistics
- Contents
- Cover -- Handbook of Psycholinguistics -- Copyright page -- Table of contents -- Preface -- List of contributors -- Chapter 1. Observations on the Past and Future of Psycholinguistics -- 1. Historical Perspectives on Psycholinguistics -- 2. Future Directions -- References -- Section 1: Language Production -- Chapter 2. Properties of Spoken Language Production -- 1. Generating Words -- 2. Summary -- References -- Chapter 3. Syntax and Production -- 1. Introduction -- 2. Syntactic Representations in Production -- 3. Processing Resources for Grammatical Encoding -- 4. Syntactic Choice -- 5. Syntax and Prosody in Production -- 6. Conclusions -- References -- Chapter 4. Speech Disorders -- 1. Introduction -- 2. Speech Delay -- 3. Vot and the Voicing Distinction in Speech Disorders -- 4. Summary -- Acknowledgments -- References -- Chapter 5. Functional Neuroimaging of Speech Production -- 1. Introduction -- References -- Section 2: Language Comprehension -- Chapter 6. Speech Perception within a Biologically Realistic Information-Theoretic Framework -- 1. Introduction -- 2. Some Fundamentals of Perception -- 3. Contrast and Low-Level Speech Perception -- 4. Maximizing Transmission of Speech Information with Multiple Dimensions -- 5. Experience and Sound Contrasts in the Native Language -- 6. To the Lexicon and Beyond -- 7. Speech in the Brain -- 8. Conclusion -- Acknowledgments -- References -- Chapter 7. The Perception of Speech -- 1. Perceptual Organization and Analysis of Speech -- 2. Perceptual Identification of the Talker -- 3. Perceptual Self-Regulation -- 4. A Concluding Word -- Acknowledgments -- References -- Chapter 8. Spoken Word Recognition -- 1. Introduction -- 2. Initial Contact -- 3. Selection: How is Activation Regulated and Recognition Achieved? -- 4. Integration: When and how is Context Integrated? -- 5. Avenues for Progress -- Acknowledgments -- References -- Chapter 9. Visual Word Recognition: The Journey from Features to Meaning (A Travel Update) -- 1. Introduction -- 2. Features, Letters, and Modeling Constraints -- 3. Getting from Letters to Words: Influences of Sublexical Levels of Organization -- 4. Lexical-Level Variables -- 5. Semantic Variables for Isolated Words -- 6. Context/Priming Effects -- 7. Attentional Control, Modularity, and time Criterion Models -- 8. Developments of New Approaches and Analytic Tools to Guide the Journey from Features to Meaning -- 9. Concluding Remarks -- Acknowledgments -- References -- Chapter 10. Lexical Processing and Sentence Context Effects -- 1. Lexical Properties -- 2. Sentence Context Effects -- References -- Chapter 11. Semantic Memory -- 1. Introduction -- 2. Quillian's Semantic Memory -- 3. Generic Semantic Memory -- 4. Theoretical Extensions, Consequences, and Divergences -- 5. Semantic Memory and the Brain -- 6. Storage Versus Access Deficits in Neuropsychological Populations -- 7. Similarity Judgments and Semantic Memory Organization in Alzheimer's Disease -- 8. Semantic Priming in Alzheimer's Disease -- 9. Conclusions an
- Format
- e-Book
- Location
- Online
Developmental origins of health and disease
https://libcat.nshealth.ca/en/permalink/provcat27252
edited by Peter Gluckman, Mark Hanson.
--Cambridge, UK:
Cambridge University Press
, 2006.
- Available Online
- View e-Book
- Location
- Online
- Available Online
- View e-Book
- Author
- Gluckman, Peter D
- Other Authors
- Hanson, Mark A
- Responsibility
- edited by Peter Gluckman, Mark Hanson
- Place of Publication
- Cambridge, UK
- Publisher
- Cambridge University Press
- Date of Publication
- 2006
- Physical Description
- xvi, 519 p., [6] p. plates
- ISBN
- 6610458057 (electronic bk.)
- Subjects (MeSH)
- Developmental Biology
- Disease Susceptibility
- Prenatal Exposure Delayed Effects
- Disease - etiology
- Contents
- Cover -- Half-title -- Title -- Copyright -- Contents -- List of Contributors -- Preface -- 1 The developmental origins of health and disease: an overview -- REFERENCES -- 2 The developmental origins' hypothesis: epidemiology -- Introduction -- Fetal, infant and childhood growth in relation to health in later life -- Ecological observations pointing to developmental influences on adult health -- Coronary heart disease -- Cohort studies of size at birth and coronary heart disease -- Infant and childhood growth and coronary heart disease -- Size of effects and potential confounding influences -- Stroke, hypertension and cardiovascular function -- Hypertension and blood pressure -- Mechanisms underlying developmental effects on hypertension and raised blood pressure -- Cardiovascular structure and function -- Serum cholesterol and blood clotting -- Type 2 diabetes and the metabolic syndrome -- Size at birth and type 2 diabetes -- Insulin resistance and the metabolic syndrome -- Obesity and the adiposity rebound -- Musculoskeletal health -- Respiratory health and atopy -- Cognitive function and mental health -- Brain growth and cognitive function in childhood and old age -- Schizophrenia and mood disorders -- Maternal influences on development and offspring health -- Periconceptional influences and the early trajectory of fetal growth -- Transgenerational effects -- Maternal influences on placental size and transfer capabilities -- Maternal diet and body composition -- Prevention of adult degenerative disease -- Conclusion -- REFERENCES -- 3 The conceptual basis for the developmental origins of health and disease -- Introduction -- Developmental disruption and developmental plasticity -- Adaptive responses during development -- Explanations of the developmental origins of adult disease -- The 'thrifty genotype' hypothesis -- The 'thrifty phenotype' hypothesis -- Gene...environment interactions and the explanation of the DOHaD paradigm -- The role of catch-up growth -- Constraint of fetal growth -- Match...mismatch, PARs and DOHaD: towards a conceptual synthesis -- ACKNOWLEDGMENTS -- REFERENCES -- 4 The periconceptional and embryonic period -- Introduction -- Embryos and epigenesis -- Embryo metabolism in response to environmental conditions -- Signal transduction and embryo developmental potential -- Gene expression changes in embryos in response to environment -- Embryo environment and cellular proliferation -- From embryo plasticity to fetal physiology -- Conclusions -- ACKNOWLEDGMENTS -- REFERENCES -- 5 Epigenetic mechanisms -- Introduction -- The nature of epigenetic information -- DNA methylation -- Epigenetic information of chromatin -- Chromatin remodelling -- Covalent histone modifications -- Epigenetics and development -- Clearing and establishing epigenetic marks during development -- Parental imprinting -- X-chromosome inactivation -- Epigenetics and nuclear cloning -- Epigenetic modifications are influenced by the environment -- Epigenetics and disease -- Defects in DNA methylation as a cause of disease -- Defects in histone modifications and nucleosome remodelling
- Format
- e-Book
- Location
- Online
Palliative neurology : a practical guide
https://libcat.nshealth.ca/en/permalink/provcat27258
Ian Maddocks ... [et al.].
--Cambridge, UK:
Cambridge University Press
, 2006.
- Available Online
- View e-Book
- Location
- Online
- Available Online
- View e-Book
- Author
- Maddocks, Ian
- Responsibility
- Ian Maddocks ... [et al.]
- Place of Publication
- Cambridge, UK
- Publisher
- Cambridge University Press
- Date of Publication
- 2006
- Physical Description
- xviii, 260 p.
- ISBN
- 6610479992 (electronic bk.)
- Subjects (MeSH)
- Nervous System Diseases - therapy
- Palliative Care - methods
- Contents
- Cover -- Half-title -- Title -- Copyright -- Contents -- Foreword -- Note on drugs and abbreviations -- SECTION I Palliative Management -- 1 Introduction to palliation -- PALLIATION, PALLIATIVE CARE AND PALLIATIVE MANAGEMENT -- 'HOSPICE' AND PALLIATION IN ADVANCED CANCER -- PALLIATIVE MANAGEMENT IN NEUROLOGY: AN INCREASINGLY RECOGNIZED NEED -- DIFFERENT TRAJECTORIES OF CARE FOR CANCER AND NEUROLOGICAL DISEASE -- PALLIATION AND NEUROSCIENCE -- 2 Characteristics of palliation -- IT IS PATIENT-CENTRED -- IT PROVIDES TRUTHFUL INFORMATION CONCERNING DISEASE STATUS AND PROGNOSIS -- IT OFFERS SUPPORT FOR FAMILY MEMBERS -- IT MAINTAINS COMPREHENSIVE CARE -- IT ENSURES CONTINUITY OF CARE -- IT RELIES ON TEAMWORK AND NETWORKING -- IT ADJUSTS ITS APPROACH IN RECOGNITION OF DETERIORATION -- IT INCLUDES BEREAVEMENT SUPPORT -- 3 Nodal points in decision-making -- INTRODUCING A PALLIATIVE MANAGEMENT APPROACH (Figure 1.3.1, Point 1) -- INTRODUCING PALLIATIVE INTERVENTIONS (Figure 1.3.1, Points 2) -- TIMING THE ONSET OF THE TERMINAL PHASE (Figure 1.3.1, Point 3) -- REFERRAL TO A PALLIATIVE CARE TEAM (Figure 1.3.1, Point 4) -- WRITING A 'DO NOT RESUSCITATE' ORDER (Figure 1.3.1, Point 5) -- INTRODUCING BEREAVEMENT CARE (Figure 1.3.1, Points 3-6) -- 4 Common deficiencies in palliative management -- POOR COMMUNICATION -- RIGID PROFESSIONAL BOUNDARIES -- INEFFECTIVE NETWORKING -- POORLY DEVELOPED TEAMWORK -- FAILURE TO MAINTAIN AN ACCESSIBLE CLINICAL RECORD -- 5 Common themes in palliation practice -- HOLISM -- RECORDING OF OBSERVATIONS -- FINDING THE BEST ANSWER: INNOVATION AND EXPERIMENT -- APPROPRIATE THERAPY REGIMENS -- SUPPORT OF CARERS -- WORKING ALONGSIDE COMPLEMENTARY AND ALTERNATIVE MEDICINE -- SECTION II Major Discomforts in Advanced Neurological Illness -- 1 Fatigue -- 2 Problems with muscles and movement -- WEAKNESS -- DISORDERS OF MUSCLE TONE AND CONTRACTION -- SEIZURES -- INVOLUNTARY MOVEMENTS -- DRUG-INDUCED MOVEMENT DISORDERS -- SYNCOPE AND FALLS -- 3 Bulbar symptoms -- IMPAIRED SPEECH -- DYSPHAGIA -- FEAR OF CHOKING -- DROOLING -- 4 Respiratory symptoms -- DYSPNOEA -- HYPOVENTILATION -- ASSISTED VENTILATION -- COUGH -- RETAINED SECRETIONS -- 5 Gastrointestinal symptoms -- DRY MOUTH -- CANDIDA INFECTION -- DYSPHAGIA -- GASTRO-OESOPHAGEAL REFLUX -- NAUSEA AND VOMITING -- BOWEL DYSFUNCTION -- NUTRITION AND HYDRATION -- 6 Urological symptoms -- URINARY RETENTION -- URGENCY AND BLADDER SPASM -- URINARY INCONTINENCE -- SEXUAL DYSFUNCTION -- 7 Pain -- TYPES AND MECHANISMS OF PAIN -- THE IMPORTANCE OF EARLY CONTROL OF PAIN -- PAIN IN NEUROLOGY -- MANAGEMENT OF NOCICEPTIVE PAIN -- NEUROPATHIC PAIN -- OPIOIDS IN CHRONIC PAIN -- CENTRAL PAIN -- OTHER STRATEGIES FOR DIFFICULT PAIN -- 8 Cognitive, behavioural and psychological symptoms -- COGNITIVE IMPAIRMENT -- DELIRIUM, AGITATION AND RESTLESSNESS -- DEPRESSION -- ANXIETY -- INSOMNIA -- GRIEF AND BEREAVEMENT -- 9 Miscellaneous symptoms -- TEMPERATURE CONTROL AND PYREXIA --tid
- Format
- e-Book
- Location
- Online
Neurology : An Evidence-Based Approach
https://libcat.nshealth.ca/en/permalink/provcat30807
Jorge G. Burneo, Bart M. Demaerschalk, Mary E. Jenkins, editors.
--New York, NY:
Springer
, c2012.
- Available Online
- View e-Book
- Holdings
- Cape Breton Regional: 2007.
- Halifax Infirmary: v. 39, 1989 - v. 45, 1995.
- Location
- Online
Evidence-based Clinical Practice (EBCP) is the conscientious, explicit, and judicious use of current best external evidence in making decisions about the care of individual patients.In neurology, practice has shifted from a rich, descriptive discipline to one of increasingly diagnostic and therapeutic interventions. Providing a comprehensive review of the current best evidence, Neurology: An Evidence-Based Approach presents this type of evidence in a concise, user-friendly and easily accessible…
- Available Online
- View e-Book
- Other Authors
- Burneo, Jorge G
- Demaerschalk, Bart M
- Jenkins, Mary E
- Responsibility
- Jorge G. Burneo, Bart M. Demaerschalk, Mary E. Jenkins, editors
- Place of Publication
- New York, NY
- Publisher
- Springer
- Date of Publication
- c2012
- Holdings
- Cape Breton Regional: 2007.
- Halifax Infirmary: v. 39, 1989 - v. 45, 1995.
- Physical Description
- 1 online resource (xiv, 368 p. : 6 ill., 3 ill. in color)
- ISBN
- 9780387885551
- ISSN
- 0028-3878
- Subjects (MeSH)
- Nervous System Diseases
- Evidence-Based Medicine
- Subjects (LCSH)
- Neurology
- Neurosurgery
- Abstract
- Evidence-based Clinical Practice (EBCP) is the conscientious, explicit, and judicious use of current best external evidence in making decisions about the care of individual patients.In neurology, practice has shifted from a rich, descriptive discipline to one of increasingly diagnostic and therapeutic interventions. Providing a comprehensive review of the current best evidence, Neurology: An Evidence-Based Approach presents this type of evidence in a concise, user-friendly and easily accessible manner. The three co-editors of this important volume are linked in their passion for evidence-based clinical practice in the clinical neurological sciences, connected to a common historical origin at the University of Western Ontario (UWO), London, Ontario Canada and influenced directly by Evidence-Based Medicine teachings of McMaster University, Hamilton, Ontario Cananda. The book is organized in three sections: Basics of Evidence-Based Clinical Practice, with an introduction to the topic, a chapter on the evolution of the hierarchy of evidence, and another chapter on guidelines for rating the quality of evidence and grading the strength of recommendation. The second section, Neurological Diseases, provides an illuminating overview of evidence-based care in ten of the most common areas in neurologic practice. The final, third section provides an outstanding roadmap for teaching evidence-based neurology with a chapter on the Evidence-Based Curriculum. A superb contribution to the literature, Neurology: An Evidence-Based Approach offers a well designed, well written, practical reference for all providers and researchers interested in the evidence-based practice of neurology.
- Contents
- Part I. Basics of Evidence-Based Clinical Practice -- 1 Evidence-Based Clinical Practice and the Neurosciences – 2. The Hierarchy of Evidence: From Unsystematic Clinical Observations to Systematic Reviews – 3. Guidelines: Rating the Quality of Evidence and Grading the Strength of Recommendations -- Part II. Neurological Diseases – 4. Stroke -- 5. Headache – 6. Epilepsy – 7. Movement Disorders – 8. Cognitive and Behavioral Neurology – 9. Neuromuscular Disorders.
- Format
- e-Book
- Location
- Online
Energy Balance and Hematologic Malignancies
https://libcat.nshealth.ca/en/permalink/provcat30967
Steven D. Mittelman, Nathan A. Berger, editors.
--New York, NY:
Springer
, c2012.
- Available Online
- View e-Book
- Location
- Online
The obesity pandemic continues to increase on a world-wide basis with over 70% of the United States population being either overweight or obese. Hematologic malignancies have recently been identified among the obesity associated malignancies spanning the lifespan from childhood to the elderly and include leukemia, myeloma, lymphoma and others. In addition to the potential etiologic association between obesity and hematologic malignancies, the presence of obesity has profound effects on therapy …
- Available Online
- View e-Book
- Other Authors
- Mittelman, Steven D
- Berger, Nathan A
- Responsibility
- Steven D. Mittelman, Nathan A. Berger, editors
- Place of Publication
- New York, NY
- Publisher
- Springer
- Date of Publication
- c2012
- Physical Description
- 1 online resource (x, 184 p. : 19 ill., 18 ill. in color)
- Series Vol.
- v. 5
- Series Title
- Energy balance and cancer
- ISBN
- 9781461424031
- Subjects (MeSH)
- Energy metabolism - physiology
- Hematologic Neoplasms - etiology
- Hematologic Neoplasms - metabolism
- Obesity - complications
- Obesity - metabolism
- Subjects (LCSH)
- Hematology
- Oncology
- Abstract
- The obesity pandemic continues to increase on a world-wide basis with over 70% of the United States population being either overweight or obese. Hematologic malignancies have recently been identified among the obesity associated malignancies spanning the lifespan from childhood to the elderly and include leukemia, myeloma, lymphoma and others. In addition to the potential etiologic association between obesity and hematologic malignancies, the presence of obesity has profound effects on therapy by impacting pharmacokinetics of chemotherapeutic agents, dose, adipocyte metabolism and drug distribution. These may be particularly important in hematopoietic stem cell transplantation. Another important aspect of the association of obesity with hematologic malignancies is the increased incidence of obesity in children who successfully complete therapy for acute lymphoblastic leukemia. This and other observations indicate important relations between the hematopoietic systems and adipose tissue metabolism. Energy Balance in Hematologic Malignancies will provide an important volume in the series on Energy Balance and Cancer and serve as a basis for better understanding etiology, mechanisms, therapeutic implications and experimental approaches. While this book should be of specific interest and utility to all pediatric and adult hematologists and oncologists dealing with hematologic malignancies, it should also provide an important resource for all investigators concerned, from a clinical or research basis, with the impact of obesity and exercise on hematologic malignancies.
- Contents
- Preface -- The Epidemiology of Obesity and Hematologic Malignancies -- Adipocytes, Lipid Metabolism and Hematopoiesis -- Mechanisms Linking Obesity and Leukemia Prognosis -- Obesity and Multiple Myeloma -- The Impact of Obesity on Pharmacokinetics and Dosing of Leukemia Chemotherapy -- The Impact of Obesity on Stem Cell Transplant -- Obesity Following Childhood Leukemia: Mechanisms and Consequences -- Physical Activity and Recovery from Hematological Malignancy -- Index.
- Format
- e-Book
- Location
- Online
Sjögren’s Syndrome : Practical Guidelines to Diagnosis and Therapy
https://libcat.nshealth.ca/en/permalink/provcat30992
Robert I. Fox, Carla M. Fox, editors.
--New York, NY:
Springer
, c2012.
- Available Online
- View e-Book
- Location
- Online
The key knowledge assembled in this book comprises today's most comprehensive resource on Sjögren's syndrome. Sjögren's patients require the care of a wide variety of clinical and surgical specialists to treat their disease and improve their quality of life. This volume presents a broad multi-disciplinary approach, enlisting the expertise of well-respected authors from around the world, covering the specialties of rheumatology, ophthalmology, oral medicine, oral surgery, otolaryngology, hematol…
- Available Online
- View e-Book
- Other Authors
- Fox, Robert I
- Fox, Carla M
- Responsibility
- Robert I. Fox, Carla M. Fox, editors
- Alternate Title
- Sjögren’s syndrome
- Place of Publication
- New York, NY
- Publisher
- Springer
- Date of Publication
- c2012
- Physical Description
- 1 online resource (xv, 506 p. : 76 ill., 41 ill. in color)
- ISBN
- 9781603279574
- Subjects (MeSH)
- Sjogren's Syndrome - diagnosis
- Sjogren's Syndrome - therapy
- Subjects (LCSH)
- Internal medicine
- Rheumatology
- Abstract
- The key knowledge assembled in this book comprises today's most comprehensive resource on Sjögren's syndrome. Sjögren's patients require the care of a wide variety of clinical and surgical specialists to treat their disease and improve their quality of life. This volume presents a broad multi-disciplinary approach, enlisting the expertise of well-respected authors from around the world, covering the specialties of rheumatology, ophthalmology, oral medicine, oral surgery, otolaryngology, hematology, and others. This practical clinical resource begins with an overview of Sjögren's myths, pearls and tips, information for referring physicians, and diagnostic and classification and criteria. The second section covers pathogenesis, providing the backbone for our understanding current diagnostics and therapeutics. The third section is devoted to clinical manifestations and therapeutic considerations. It covers the entire spectrum of symptoms and treatment, infused with the experience and astute clinical observations of the book's contributors. With system-wide coverage of local and systemic therapy, the book examines current therapy, biologics, and emerging therapeutic targets. Presenting many international perspectives, this book creates an inter-connective conduit for the global community of Sjögren's patients and physicians.
- Contents
- Part I. Introduction -- Introduction -- A Note from Sweden: Recollection of Henrik Sjögren -- Myths, Pearls, and Tips Regarding Sjögren's Syndrome -- Providing Information to Referring Physicians and Patients -- Part II. Classification Criteria and Disease Status Activity, Histology of Salivary Gland Biopsy, and Imaging -- Current Concepts on Classification Criteria and Disease Status Indexes in Sjögren's Syndrome -- Histopathology and Glandular Biopsies in Sjögren's Syndrome -- Imaging Technology in Sjögren's Syndrome: Non-invasive Evaluation of the Salivary Glands -- Part III. Mechanisms of Pathogenesis -- Genomics and Viruses in Sjögren's Syndrome -- Autoantibodies and Autoantigens in Sjögren's Syndrome -- B-cell Epitopes of Sjögren's Syndrome Related Autoantigens Ro/SSA and La/SSB -- Neurobiology and Hormonal Control of Lacrimal and Salivary Gland Function -- Part IV. Clinical and Therapeutic Considerations -- Overview of Management of Dry Eye Associated with Sjögren's Syndrome -- Pathogenesis: Emphasis on Dry Eye and the Role of the Lacrimal Functional Unit in Sjögren's Syndrome -- Oral and Dental Manifestations of Sjögren's Syndrome: Current Approaches to Diagnostics and Therapy -- Etiology and Pathogenesis of Sjögren’s Syndrome with Special Emphasis on the Salivary Glands -- Otolaryngologic Manifestations of Sjögren's Syndrome -- Extraglandular Manifestations of Sjögren’s Syndrome (SS): Dermatologic, Arthritic, Endocrine, Pulmonary, Cardiovascular, Gastroenterology, Renal, Urology, and Gynecologic Manifestations -- Therapy of Dermatologic, Renal, Cardiovascular, Pulmonary, Gynecologic, Gastro-enterologic, Urologic and Fibromyalgia Manifestations Including Special Considerations at the Time of Surgery -- Current Treatment of Extraglandular Manifestations with Disease Modifying and Immunosuppressive Agents -- Lymphoproliferation and Lymphoma in Sjögren's Syndrome -- Fatigue, Dryness, and Quality of Life as Clinical Trial Outcomes in Primary Sjögren's Syndrome -- The Neurological Manifestations of Sjögren's Syndrome: Diagnosis and Treatment -- Part V. The Views from Japan, China, India, and Australia -- New Approaches for the Management of Dry Mouth in Sjögren's Syndrome in Japan -- New Approaches for the Management of Dry Mouth and Dry Eye in Sjögren’s Syndrome in Japan -- Sjögren's Syndrome in Australia: Clinical Practice and Research -- Primary Sjögren's Syndrome: Report from India -- Sjögren's Syndrome in China -- Sjögren's Syndrome in China -- Sjögren's Syndrome in Israel: A Scientific Point of View -- Part VI. Future Perspectives -- Looking Into the Future—The EULAR Disease Activity Scores: Toward a Consensual Evaluation of Primary Sjögren's Syndrome -- Looking into the Crystal Ball: Initiatives from the Sjögren's Syndrome Foundation that Will Impact Patient Care -- Biological Treatment for Sjögren's Syndrome -- Looking Into the Future—Emerging Therapies Based on Pathogenesis -- Into the Future: Autonomic Neuropathy, MicroRNAs, and Gene Therapy.
- Format
- e-Book
- Location
- Online
Adenovirus Epithelial Keratitis and Thygeson's Superficial Punctate Keratitis : In Vivo Morphology in the Human Cornea
https://libcat.nshealth.ca/en/permalink/provcat31124
Helena M. Tabery.
--Berlin, Heidelberg:
Springer
, c2012.
- Available Online
- View e-Book
- Location
- Online
Adenovirus epithelial keratitis and Thygeson's superficial punctate keratitis (TSPK) are apparently disparate diseases. While adenovirus eye infections are very common, caused by a known agent, and highly infectious, TSPK is comparatively rare, of unknown causation, and seemingly non-contagious. Despite these differences, the two diseases are often confused in clinical practice owing to the similarity between adenovirus epithelial infiltrates and 'coarse' epithelial TSPK lesions. This book pres…
- Available Online
- View e-Book
- Other Authors
- Tabery, Helena M
- Responsibility
- Helena M. Tabery
- Place of Publication
- Berlin, Heidelberg
- Publisher
- Springer
- Date of Publication
- c2012
- Physical Description
- 1 online resource (x, 131 p. : 148 ill. in color)
- ISBN
- 9783642216343
- Subjects (MeSH)
- Adenovirus Infections, Human
- Corneal opacity - pathology
- Epithelium, Corneal - pathology
- Keratitis - pathology
- Keratitis - case reports
- Subjects (LCSH)
- Ophthalmology
- Abstract
- Adenovirus epithelial keratitis and Thygeson's superficial punctate keratitis (TSPK) are apparently disparate diseases. While adenovirus eye infections are very common, caused by a known agent, and highly infectious, TSPK is comparatively rare, of unknown causation, and seemingly non-contagious. Despite these differences, the two diseases are often confused in clinical practice owing to the similarity between adenovirus epithelial infiltrates and 'coarse' epithelial TSPK lesions. This book presents the morphological features, dynamics, and sequelae of adenovirus and Thygeson's keratitides captured at high magnification in the living human cornea. It thereby fills the existing void between conventional photographs and slit-lamp observations. Case reports demonstrate the importance of patient history in differential diagnosis, illustrate the need for familiarity with early manifestations of adenovirus infections, and assist in the diagnosis of rare variants of TSPK. Furthermore, the detailed observations on the natural course of the diseases ensure that the book will serve not only as a diagnostic tool but also as a reference when evaluating the effects of potential new treatments.
- Contents
- Part I. Adenovirus Epithelial Keratitis -- 1. The Morphology of Adenovirus Epithelial Keratitis -- 2. Adenovirus Type 8 Epithelial Keratitis: The Development, Accompanying Signs, and Sequelae -- 3. Adenovirus Epithelial Keratitis Caused by Various Serotypes (Ad3, 4, and 7) -- 4. The Development of Subepithelial Infiltrates: A Sequence of Events -- Part II. Thygeson’s Superficial Punctate Keratitis -- 5. The Morphology of Thygeson’s Superficial Punctate Keratitis (TSPK) -- 6. Typical Cases of Thygeson’s Punctate Epithelial Keratitis (TSPK) -- 7. Three Atypical Cases of Thygeson’s Superfi cial Punctate Keratitis (TSPK).
- Format
- e-Book
- Location
- Online
Nevogenesis : mechanisms and clinical implications of nevus development
https://libcat.nshealth.ca/en/permalink/provcat31180
Ashfaq A. Marghoob, editor.
--Berlin, Heidelberg:
Springer
, c2012.
- Available Online
- View e-Book
- Location
- Online
Paul Gerson Unna's "Abtropfung" theory that nevi develop through migration of nevus cells from the epidermis to the dermis prevailed for almost a century until the "Hochsteigerung" theory postulated the reverse pattern of migration based on newly acquired observations from histopathology and studies of embryogenesis. Most recently, however, new insights gained from epidemiology, cross-sectional and longitudinal studies of nevi, dermoscopy and confocal microscopy, and cellular and molecular stud…
- Available Online
- View e-Book
- Other Authors
- Marghoob, Ashfaq A
- Responsibility
- Ashfaq A. Marghoob, editor
- Place of Publication
- Berlin, Heidelberg
- Publisher
- Springer
- Date of Publication
- c2012
- Physical Description
- 1 online resource (viii, 160 p. : 60 ill., 59 ill. in color)
- ISBN
- 9783642283970
- Subjects (MeSH)
- Nevus - physiopathology
- Skin Neoplasms - physiopathology
- Subjects (LCSH)
- Dermatology
- Oncology
- Abstract
- Paul Gerson Unna's "Abtropfung" theory that nevi develop through migration of nevus cells from the epidermis to the dermis prevailed for almost a century until the "Hochsteigerung" theory postulated the reverse pattern of migration based on newly acquired observations from histopathology and studies of embryogenesis. Most recently, however, new insights gained from epidemiology, cross-sectional and longitudinal studies of nevi, dermoscopy and confocal microscopy, and cellular and molecular studies have brought into question both of the aforementioned theories. This book provides a comprehensive guide to current knowledge about nevogenesis by presenting these latest advances and in addition discusses issues yet to be resolved. It will assist practicing physicians in effectively managing patients with a variety of nevi and will also be of great value to researchers in the field. Importantly, since nevi are associated with an increased risk of melanoma, understanding nevogenesis may help to unravel some of the mysteries of melanomagenesis.
- Contents
- Nevogenesis: Changing Theories -- Classifying Melanocytic Nevi -- Evolution of Nevi -- The Dual Pathway of Nevogenesis -- Confocal Microscopy: Improving Our Understanding of Nevogenesis -- Nevi In Children And Adults: Dermoscopic Patterns And The Development of New Nevi -- Etiology of Congenital Melanocytic Nevi And Related Conditions -- Molecular Nevogenesis -- Nevogenesis: A Benign Metastatic Process? -- Nevus Senescence -- Gene-Environment Interactions In Nevogenesis -- Malignant Transformation of Melanocytic Nevi -- Disappearance of Melanocytic Nevi -- Index.
- Format
- e-Book
- Location
- Online
Keratoconjunctivitis sicca and filamentary keratopathy : in vivo morphology in the human cornea and conjunctiva
https://libcat.nshealth.ca/en/permalink/provcat31192
Helena M. Tabery, author.
--Berlin, Heidelberg:
Springer
, c2012.
- Available Online
- View e-Book
- Location
- Online
This book presents in vivo captured high-magnification images of two conditions: keratoconjunctivitis sicca (KCS, or dry eye), an extremely common disease of the ocular surface, and filamentary keratopathy, a relatively rare phenomenon most commonly associated with KCS. Although most of the images of KCS originated from patients with Sjœgren's syndrome, they fairly represent the broad spectrum of ocular surface changes seen in the condition. The appearance of the ocular surface and of the mucus…
- Available Online
- View e-Book
- Author
- Tabery, Helena M
- Responsibility
- Helena M. Tabery, author
- Place of Publication
- Berlin, Heidelberg
- Publisher
- Springer
- Date of Publication
- c2012
- Physical Description
- 1 online resource (xiii, 196 p. : 218 ill. in color)
- ISBN
- 9783642310287
- Subjects (MeSH)
- Corneal Diseases
- Keratitis
- Keratoconjunctivitis sicca
- Subjects (LCSH)
- Ophthalmology
- Abstract
- This book presents in vivo captured high-magnification images of two conditions: keratoconjunctivitis sicca (KCS, or dry eye), an extremely common disease of the ocular surface, and filamentary keratopathy, a relatively rare phenomenon most commonly associated with KCS. Although most of the images of KCS originated from patients with Sjœgren's syndrome, they fairly represent the broad spectrum of ocular surface changes seen in the condition. The appearance of the ocular surface and of the mucus component discernible in the tear film is clearly depicted, and long-term observations, less common KCS cases, and images showing iatrogenic epithelial damage are included. The images of filamentary keratopathy clearly reveal the components of the ocular surface appendices, termed filaments, and assist in explaining the mechanisms underlying the formation of these filaments. The photographs show phenomena captured in various illumination modes, without staining and after staining with diagnostic dyes, and the photographic sequences illustrate their dynamics. The images reflect the in vivo situation. Once aware of the various phenomena, anyone working with standard diagnostic equipment - the slit lamp and the diagnostic dyes- will be able to detect almost all of them. The book will be invaluable for all who deal with ocular surface diseases, including general practitioners, medical eye specialists, ocular surgeons, optometrists, opticians, and rheumatologists.
- Contents
- Part I. Keratoconjunctivitis Sicca: The Mucus in the Preocular Tear Film -- The Corneal Surface -- The Conjunctival Surface -- Case Reports -- Corneal Epitheliopathy After Herpes Zoster Ophthalmicus (HZO). Part II. Filamentary Keratopathy: The Morphology and Dynamics of Filaments -- Case Reports -- Final Remark -- Bibliography -- Index.
- Format
- e-Book
- Location
- Online
Cardiac tumor pathology
https://libcat.nshealth.ca/en/permalink/provcat32452
Cristina Basso, Marialuisa Valente, Gaetano Thiene, editors.
--New York, NY:
Humana Press
, c2013.
- Available Online
- View e-Book
- Location
- Online
Cardiac tumors were once a nosographic entity of scarce clinical interest because of the rarity and of the intrinsic diagnostic and therapeutic impossibilities, and were considered a fatal morbid entity. It has now become a topical subject due to advances in clinical imaging (echo, magnetic resonance, computed tomography) as well as innovation in technologies of in-vivo diagnosis. Cardiac Tumor Pathology presents a spectacular example of these advances with clinico-pathologic correlations. Thi…
- Available Online
- View e-Book
- Other Authors
- Basso, Cristina
- Valente, Marialuisa
- Thiene, Gaetano
- Responsibility
- Cristina Basso, Marialuisa Valente, Gaetano Thiene, editors
- Place of Publication
- New York, NY
- Publisher
- Humana Press
- Date of Publication
- c2013
- Physical Description
- 1 online resource (xiv, 197 p. : 139 ill., 105 ill. in color)
- Series Title
- Current clinical pathology
- ISBN
- 9781627031431
- Subjects (MeSH)
- Heart Neoplasms - pathology
- Subjects (LCSH)
- Radiology, Medical
- Cardiology
- Oncology
- Pathology
- Abstract
- Cardiac tumors were once a nosographic entity of scarce clinical interest because of the rarity and of the intrinsic diagnostic and therapeutic impossibilities, and were considered a fatal morbid entity. It has now become a topical subject due to advances in clinical imaging (echo, magnetic resonance, computed tomography) as well as innovation in technologies of in-vivo diagnosis. Cardiac Tumor Pathology presents a spectacular example of these advances with clinico-pathologic correlations. This timely volume covers history, epidemiology, demographics, clinical diagnosis, pathology, imaging by echo, CT and MRI of both benign and malignant cardiac tumors, either primary or secondary. Chemotherapy of malignant neoplasms is also addressed. Special emphasis is given to clinico-pathologic correlations. With all chapters written by experts in their fields, this volume will serve as a useful resource for physicians dealing with, and interested in, this special branch of cardiac oncology and will represent a useful guide for pathologists, clinicians, cardiologists, cardiac surgeons, and radiologists as well as for postgraduate students training in these areas.
- Contents
- Cardiac Tumors: From Autoptic Observations to Surgical Pathology in the Era of Advanced Cardiac -- Cardiac Tumors: Classification and Cardiac Myxoma -- Other Benign Cardiac Tumors -- Primary Cardiac Tumors in the Pediatric -- Primary Malignant Tumors of the Heart -- Echocardiographic Approach to the Diagnosis of Cardiac -- Echocardiography of Cardiac Masses: From Two- to Three-Dimensional Imaging -- New Cardiac Imaging Techniques: Magnetic Resonance and Computed -- Surgical Management of Cardiac Neoplasms -- Cardiac -- Systemic Therapy, Radiotherapy, and Cardiotoxicity -- Novelties in Immunohistochemical and Molecular Study of Cardiac Tumors – Index.
- Format
- e-Book
- Location
- Online
Carotenoids and human health
https://libcat.nshealth.ca/en/permalink/provcat32459
Sherry A. Tanumihardjo, editor.
--New York, NY:
Humana Press
, c2013.
- Available Online
- View e-Book
- Location
- Online
Carotenoids and Human Health provides an introduction to food sources and metabolism. Written by experts in their fields and including the most up-to-date information, this volume serves as an in-depth guide to studies that have been performed in humans and observations that have been made in population level assessments. Special emphasis is given to associations with disease, as well as the importance of carotenoids internationally, specifically as a source of vitamin A for the world. Compreh…
- Available Online
- View e-Book
- Other Authors
- Tanumihardjo, Sherry A
- Responsibility
- Sherry A. Tanumihardjo, editor
- Place of Publication
- New York, NY
- Publisher
- Humana Press
- Date of Publication
- c2013
- Physical Description
- 1 online resource (xxiii, 331 p. : 58 ill., 30 ill. in color)
- Series
- Nutrition and Health
- Series Title
- Nutrition and health (Totowa, N.J.)
- ISBN
- 9781627032032
- Subjects (MeSH)
- Carotenoids - physiology
- Nutritional Physiological Phenomena
- Subjects (LCSH)
- Personal health and hygiene
- Abstract
- Carotenoids and Human Health provides an introduction to food sources and metabolism. Written by experts in their fields and including the most up-to-date information, this volume serves as an in-depth guide to studies that have been performed in humans and observations that have been made in population level assessments. Special emphasis is given to associations with disease, as well as the importance of carotenoids internationally, specifically as a source of vitamin A for the world. Comprehensive and easy to use, Carotenoids and Human Health is a very useful resource for nutritionists, registered dieticians, medical students, and graduate students.
- Contents
- Food Sources of Carotenoids -- Carrots of Various Colors -- Carotenoid Metabolism and Enzymology -- Reactive Oxygen and Nitrogen Species in Biological Systems: Reactions and Regulation by Carotenoids -- Kinetic Studies with Carotenoids -- Carotenoid Bioavailability: Influence of Dietary Lipid and Fiber -- Host Factors that Affect Carotenoid Metabolism -- Host Factors: Gender and Body Composition -- Carotenoid Metabolism and Health in Pregnancy and Lactation -- Carotenoids in Early Life -- Provitamin A Carotenoids and Cancer Prevention -- Lycopene and Cancer -- Lutein and Zeaxanthin and Eye Disease -- Carotenoids and Bone Health -- Provitamin A Carotenoids as a Dietary Source of Vitamin A -- Provitamin A Carotenoids and Immune Function -- Biofortification of Maize with Provitamin-A Carotenoids -- Horticultural Crops as a Source of Carotenoids -- Orange Sweetpotato as a Staple or Complementary Food -- International Efforts to Eradicate Vitamin A Deficiency -- Index.
- Format
- e-Book
- Location
- Online
Strengths-based nursing care : health and healing for person and family
https://libcat.nshealth.ca/en/permalink/provcat32699
Laurie N. Gottlieb, in collaboration with Bruce Gottlieb.
--New York, NY:
Springer Publishing Company
, c2013.
- Available Online
- View e-Book
- Location
- Online
- Available Online
- View e-Book
- Author
- Gottlieb, Laurie N
- Responsibility
- Laurie N. Gottlieb, in collaboration with Bruce Gottlieb
- Place of Publication
- New York, NY
- Publisher
- Springer Publishing Company
- Date of Publication
- c2013
- Physical Description
- 1 online resource, 413 p.
- ISBN
- 9780826195876
- Subjects (MeSH)
- Cooperative Behavior
- Nurse-Patient Relations
- Nursing Care - psychology
- Patient Care Planning
- Patient Participation
- Professional-Family Relations
- Contents
- Why a strengths-based approach to care? -- What guides practice? -- Values underlying strengths-based nursing care -- What are strengths? Characteristics of strengths -- Essential nurse qualities required for strengths-based care -- Retraining the eight senses for nursing practice -- Nursings professional gaze : observations for clinical judgment and decision making -- Reforming skills of social involvement : attunement, authentic presence, attentive listening, and clinical conversation -- The spiraling process for uncovering and discovering strengths -- Approaches for working with strengths.
- Format
- e-Book
- Location
- Online
Interdisciplinary Concepts in Cardiovascular Health. Volume I, Primary Risk Factors
https://libcat.nshealth.ca/en/permalink/provcat40815
Ichiro Wakabayashi, Klaus Groschner, editors.
--Vienna:
Springer
, c2013.
- Available Online
- View e-Book
- Location
- Online
This book provides an introduction to the principles of both cardiovascular epidemiology and molecular pathophysiology; as a unique aspect, it also outlines and discusses the molecular concepts underlying epidemiological observations. This first volume is focused on the genetic and molecular basis of pathogenesis and the role of environmental factors triggering cardiovascular dysfunctions. The book promotes the use of interdisciplinary approaches in the field of preventive medicine based on rec…
- Available Online
- View e-Book
- Other Authors
- Wakabayashi, Ichiro
- Groschner, Klaus
- Responsibility
- Ichiro Wakabayashi, Klaus Groschner, editors
- Place of Publication
- Vienna
- Publisher
- Springer
- Date of Publication
- c2013
- Physical Description
- 1 online resource (xiii, 224 p. : ill.)
- ISBN
- 9783709113349
- 9783709113332 (print ed.)
- Subjects (MeSH)
- Cardiovascular Diseases - epidemiology
- Cardiovascular Diseases - physiopathology
- Cardiovascular Physiological Phenomena
- Risk Factors
- Abstract
- This book provides an introduction to the principles of both cardiovascular epidemiology and molecular pathophysiology; as a unique aspect, it also outlines and discusses the molecular concepts underlying epidemiological observations. This first volume is focused on the genetic and molecular basis of pathogenesis and the role of environmental factors triggering cardiovascular dysfunctions. The book promotes the use of interdisciplinary approaches in the field of preventive medicine based on recent advances in molecular and cellular pathophysiology. The book offers a valuable resource work for researchers in basic biomedical fields and clinical scientists alike, as well as guidelines for novel avenues of research in both basic pathophysiology and cardiovascular therapy and prevention.
- Contents
- 1. Basic Principles of Molecular Pathophysiology and Etiology of Cardiovascular Dysorders -- 2. Aging -- 3. Gender -- 4. Gene Polymorphisms and Signaling Defects -- 5. Diet and Nutrition to Prevent and Treat Cardiovascular Diseases -- 6. Physical Activity and Cardiovascular Diseases -- 7. Alcohol -- 8. Tobacco -- 9. Socioeconomic Aspects of Cardiovascular Health -- 10. Stress and Psychological Factors.
- Format
- e-Book
- Location
- Online
Differential Diagnosis in Pediatric Dermatology
https://libcat.nshealth.ca/en/permalink/provcat40826
Ernesto Bonifazi.
--Milan:
Springer
, c2013.
- Available Online
- View e-Book
- Location
- Online
Differential diagnosis in pediatric dermatology requires not only a direct experience in the field, but also an inclination to symptoms observations and analysis.This book, the first exclusively devoted to this topic, covers the full range of relevant conditions: inherited skin disorders; nevi; viral, bacterial, fungal, and parasitic infections; acne; allergic diseases; autoimmune skin disorders; connective tissue diseases; tumors; and miscellaneous conditions. Each chapter addresses the differ…
- Available Online
- View e-Book
- Author
- Bonifazi, Ernesto
- Responsibility
- Ernesto Bonifazi
- Place of Publication
- Milan
- Publisher
- Springer
- Date of Publication
- c2013
- Physical Description
- 1 online resource (xv, 150 p. : ill.)
- ISBN
- 9788847028593
- 9788847028586 (print ed.)
- Subjects (MeSH)
- Diagnosis, Differential
- Skin Diseases - diagnosis
- Abstract
- Differential diagnosis in pediatric dermatology requires not only a direct experience in the field, but also an inclination to symptoms observations and analysis.This book, the first exclusively devoted to this topic, covers the full range of relevant conditions: inherited skin disorders; nevi; viral, bacterial, fungal, and parasitic infections; acne; allergic diseases; autoimmune skin disorders; connective tissue diseases; tumors; and miscellaneous conditions. Each chapter addresses the differential diagnosis between two (or occasionally three or four) dermatological conditions. All chapters are just two pages long, containing between two and six images and a very short text emphasizing the clinical differences between the diseases in question. At the end of each chapter, a summary highlights one or two characteristics essential for the differential diagnosis. The volume will represent an ideal tool for pediatric dermatologists, pediatricians, and GPs, and will help them in the diagnosic process.
- Contents
- Inherited Skin Disorders -- Nevi -- Viral Infections -- Bacterial Infections -- Fungal Infections -- Parasitic Infestations -- Acne -- Allergic Diseases -- Autoimmune Skin Disorders -- Miscellaneous Items -- Connective Tissue Diseases -- Tumors.
- Format
- e-Book
- Location
- Online
The beginning psychotherapist's companion
https://libcat.nshealth.ca/en/permalink/provcat32982
Jan Willer.
(2nd ed.)
--Oxford, UK:
Oxford University Press
, c2014.
- Available Online
- View e-Book
- Location
- Online
Filling in the gaps from students' lack of experience and confidence, The Beginning Psychotherapist's Companion, Second Edition is a supportive and empathetic guide, addressing real-world concerns and providing essential insights not taught in textbooks. With a reassuring and clear writing style, Willer offers practical suggestions and clinical examples to address the professional development and emotional concerns of the beginning psychotherapist. She guides readers through structuring the fi…
- Available Online
- View e-Book
- Author
- Willer, Jan
- Responsibility
- Jan Willer
- Edition
- 2nd ed.
- Place of Publication
- Oxford, UK
- Publisher
- Oxford University Press
- Date of Publication
- c2014
- Physical Description
- 1 online resource, 467 p.
- ISBN
- 9780199330317
- Subjects (MeSH)
- Psychotherapy - methods
- Practice Management
- Professional-Patient Relations
- Psychotherapy - organization & administration
- Abstract
- Filling in the gaps from students' lack of experience and confidence, The Beginning Psychotherapist's Companion, Second Edition is a supportive and empathetic guide, addressing real-world concerns and providing essential insights not taught in textbooks. With a reassuring and clear writing style, Willer offers practical suggestions and clinical examples to address the professional development and emotional concerns of the beginning psychotherapist. She guides readers through structuring the first session, making clinical observations, and establishing a therapeutic alliance.
- Contents
- Acknowledgments -- Introduction -- Section I. The Psychotherapist's Self And Relationships -- 1 The Psychotherapist's Self -- 2 The Supervisor-Supervisee Relationship -- 3 The Therapeutic Frame -- 4 Boundaries -- 5 Psychotherapist-Client Differences and Coping with Prejudice -- 6 Professional Electronic Communications and Data Security -- Section II. Getting Started With Psychotherapy -- 7 Confidentiality and Informed Consent -- 8 Making Clinical Observations -- 9 Making a Diagnosis -- 10 Professional Phone Contacts and the Initial Phone Call -- 11 The First Session: Preparation, Tasks, and Structure -- 12 Progress Notes and the Chart -- 13 Starting Psychotherapy and Stabilizing the Client -- Section III. Referrals -- 14 Psychotropic Medication: Referrals and Adherence -- 15 Health-Related Referrals -- 16 Mental Health Referrals -- Section IV. Crisis Readiness -- 17 Managing Crises Step-by-Step -- 18 Assessing Suicide Risk and Warning Signs -- 19 Suicide Prevention, Risk Reduction, and Documentation -- 20 Violence Risk Management -- 21 Child and Elder Maltreatment, Intimate Partner Violence, and Rape Crises -- Section V. Caring for Yourself and Your Clients -- 22 Challenging Relationships and Emotions -- 23 Becoming a Psychotherapist: Challenges, Rewards, and Growth -- Afterword -- About the Author -- References -- Index.
- Format
- e-Book
- Location
- Online
Fundamentals of evidence-based health care and translational science
https://libcat.nshealth.ca/en/permalink/provcat33439
Francesco Chiappelli.
--Heidelberg:
Springer
, c2014.
- Available Online
- View e-Book
- Location
- Online
Comparative effectiveness research - the conduct and synthesis of systematic research in order to compare the benefits and harms of alternative treatment options - is of critical importance in enabling informed health care decisions to be made. This user-friendly, practical handbook examines in depth how best to perform such comparative effectiveness research. A wide range of topics and methods are discussed, including research synthesis, sampling analysis, assessment of evidence design, system…
- Available Online
- View e-Book
- Author
- Chiappelli, Francesco
- Responsibility
- Francesco Chiappelli
- Place of Publication
- Heidelberg
- Publisher
- Springer
- Date of Publication
- c2014
- Physical Description
- 1 online resource (xxvii, 394 pages)
- ISBN
- 9783642418570 (electronic bk.)
- 9783642418563
- Subjects (MeSH)
- Comparative Effectiveness Research
- Decision Making
- Evidence-Based Medicine
- Outcome Assessment, Health Care
- Subjects (LCSH)
- Drugs - Effectiveness - Research - Methodology
- Abstract
- Comparative effectiveness research - the conduct and synthesis of systematic research in order to compare the benefits and harms of alternative treatment options - is of critical importance in enabling informed health care decisions to be made. This user-friendly, practical handbook examines in depth how best to perform such comparative effectiveness research. A wide range of topics and methods are discussed, including research synthesis, sampling analysis, assessment of evidence design, systematic evaluation of statistical analysis, and meta-analysis. The discussion extends well beyond the fundamentals by encompassing 'complex' systematic reviews, 'cumulative' meta-analyses, and logic-based versus utility-based decision making. Health care providers, researchers, instructors, and students will all find this to be an invaluable reference on the compelling current issues and important analytical tools in comparative effectiveness research.
- Contents
- Part I. Fundamental Implications for Clinical Practice -- 1. Translational Effectiveness in the Context of Translational Science -- 2. Comparative Effectiveness Analysis and Evidence-Based Decisions -- 3. Methodology I: The Best Available Evidence -- 4. Methodology II: Sampling and Assessment of the Evidence -- 5. Methodology III: Systematic Evaluation of the Statistical Analysis: Data Analysis in Research Synthesis -- Part II. Optimizing Clinical Practice-Based Patient-Centered Outcomes Research -- 6. Getting and Understanding Data -- 7. Obtaining Data -- 8. Describing and Analyzing Data -- 9. Translational Effectiveness Analysis -- 10. Optimizing Clinical Outcomes by Individualizing Observations -- 11. Evaluation in Patient-Centered Outcomes Research -- 12. Translational Effectiveness in Practice-Based Patient-Centered Outcomes Research.
- Format
- e-Book
- Location
- Online
Chronic radiation syndrome
https://libcat.nshealth.ca/en/permalink/provcat33705
Alexander V. Akleyev.
--Heidelberg:
Springer
, c2014.
- Available Online
- View e-Book
- Location
- Online
This book covers all aspects of chronic radiation syndrome (CRS) based on observations in a unique sample of residents of the Techa riverside villages in the southern Urals who were exposed to radioactive contamination in the 1950s owing to releases of liquid radioactive wastes from Mayak Production Association, which produced plutonium for weapons. In total, 940 cases of CRS were diagnosed in this population and these patients were subjected to detailed analysis. The opening chapters address t…
- Available Online
- View e-Book
- Author
- Akleev, A. V
- Responsibility
- Alexander V. Akleyev
- Place of Publication
- Heidelberg
- Publisher
- Springer
- Date of Publication
- c2014
- Physical Description
- 1 online resource (xxi, 410 pages)
- ISBN
- 9783642451171 (electronic bk.)
- 9783642451164
- Subjects (MeSH)
- Chronic Disease
- Radiation Injuries - etiology
- Radiation Injuries - therapy
- Subjects (LCSH)
- Radiation injuries
- Radiotherapy
- Hematology
- Other Subjects
- Russia
- Abstract
- This book covers all aspects of chronic radiation syndrome (CRS) based on observations in a unique sample of residents of the Techa riverside villages in the southern Urals who were exposed to radioactive contamination in the 1950s owing to releases of liquid radioactive wastes from Mayak Production Association, which produced plutonium for weapons. In total, 940 cases of CRS were diagnosed in this population and these patients were subjected to detailed analysis. The opening chapters address the definition and classification of CRS, epidemiology and pathogenesis, covering molecular and cellular mechanisms, radioadaptation, and the role of tissue reactions. The pathoanatomy of CRS during the development and recovery stages is discussed for all organ systems. Clinical manifestations of CRS at the different stages are then described in detail and the dynamics of hematopoietic changes are thoroughly examined. In the following chapters, principles of diagnosis (including assessment of the exposure doses to critical organs) and differential diagnosis from a wide range of other conditions are discussed and current and potential treatment options, described. The medical and social rehabilitation of persons with CRS is also covered. This book, which casts new light on the condition, will be of value for all practitioners and researchers with an interest in CRS.
- Contents
- 1. Definition, Classification, and Clinical Presentation of Chronic Radiation Syndrome (CRS) Associated with Total Exposure to External Radiation -- 2. Epidemiology of Chronic Radiation Syndrome -- 3. Mechanisms Involved in Chronic Radiation Exposure Effects: Pathogenesis of Chronic Radiation Syndrome -- 4. Pathoanatomy of Chronic Radiation Syndrome During the Period of Its Development and at Recovery Stage -- 5. Clinical Manifestations of Chronic Radiation Syndrome -- 6. Dynamics of Hematopoietic Changes in Persons with CRS -- 7. Diagnosis of Chronic Radiation Syndrome -- 8. Treatment of Persons with CRS -- 9. General Conclusions.
- Format
- e-Book
- Location
- Online
Notes of a radiology watcher
https://libcat.nshealth.ca/en/permalink/provcat33712
Stephen R. Baker.
--Cham, Switzerland:
Springer
, c2014.
- Available Online
- View e-Book
- Location
- Online
- Available Online
- View e-Book
- Author
- Baker, Stephen R
- Responsibility
- Stephen R. Baker
- Place of Publication
- Cham, Switzerland
- Publisher
- Springer
- Date of Publication
- c2014
- Physical Description
- 1 online resource (xiv, 332 pages)
- ISBN
- 9783319016771 (electronic bk.)
- 9783319016764
- Subjects (MeSH)
- Radiology - Essays
- Subjects (LCSH)
- Radiology
- Radiology, Medical
- Contents
- Part I. Early residency : preparation and participation -- Part II. Late residency, fellowship and just beyond -- Part III. Radiology elsewhere in the world -- Part IV. Radiologist inclusiveness : minority features -- Part V. The appearances and implications of the radiology report -- Part VI. Radiologist responsibilities -- Part VII. Quality considerations -- Part VIII. Malpractice apology and appropriateness -- Part IX. Opportunities for radiologists -- Part X. The challenges facing American radiologists -- Part XI. Research -- Part XII. Radiation dose -- Part XIII. Nooks and crannies in general radiology including some forgotten observations.
- Format
- e-Book
- Location
- Online
The glaucomas. Volume II, Open angle glaucoma and angle closure glaucoma
https://libcat.nshealth.ca/en/permalink/provcat33777
Roberto Sampaolesi, Juan Roberto Sampaolesi, Jorge Zarate.
--Berlin, Heidelberg:
Springer
, c2014.
- Available Online
- View e-Book
- Location
- Online
This second volume in a short series on the glaucomas is devoted to the two main types of the disease, open angle glaucoma and angle closure glaucoma. The contents are based on observations and experience gained during the management of more than 40,000 hospital and 7,000 private patients, with follow-up of 10 to 50 years. The book is comprehensive in scope. All aspects of diagnosis are carefully examined, surgical indications and techniques are explained, and the role of medical treatment is e…
- Available Online
- View e-Book
- Author
- Sampaolesi, Roberto
- Other Authors
- Sampaolesi, Juan R.
- Zárate, J.
- Responsibility
- Roberto Sampaolesi, Juan Roberto Sampaolesi, Jorge Zarate
- Alternate Title
- Open angle glaucoma and angle closure glaucoma
- Place of Publication
- Berlin, Heidelberg
- Publisher
- Springer
- Date of Publication
- c2014
- Physical Description
- 1 online resource (xlix, 962 pages)
- ISBN
- 9783642355004 (electronic bk.)
- 9783642354991
- Subjects (MeSH)
- Glaucoma, Open-Angle
- Glaucoma, Angle-Closure
- Subjects (LCSH)
- Angle-closure glaucoma
- Open-angle glaucoma
- Notes
- Accompanying materials may not be available in some electronic versions.
- Abstract
- This second volume in a short series on the glaucomas is devoted to the two main types of the disease, open angle glaucoma and angle closure glaucoma. The contents are based on observations and experience gained during the management of more than 40,000 hospital and 7,000 private patients, with follow-up of 10 to 50 years. The book is comprehensive in scope. All aspects of diagnosis are carefully examined, surgical indications and techniques are explained, and the role of medical treatment is evaluated. Importantly, chapters are included on topics that are frequently overlooked in other books but are important to early diagnosis, such as diurnal pressure curve, HRT, and non-conventional perimetry.
- Contents
- History -- Concept of Glaucoma Pathogenesis -- Epidemiology and Etiopathogenia -- Structure and Function of the Tissues That Are in Contact with the Aqueous Humor -- Genetics, Heredity, and Molecular Biology in Glaucoma -- Aqueous Humor: Physiology of the Aqueous Humor -- Intraocular Pressure Measurement: Tonometry -- Indentation Tonometry -- Ocular Rigidity or Resistance to Distension -- Applanation Tonometry -- The Role of Pachimetry -- Pascal Tonometer: Dynamic Contour Tonometry -- Continuous IOP Monitoring Devices: The Micro-ocular Glaucoma Holter -- Episcleral Venous Pressure -- Daily Pressure Curve -- Early Diagnosis of Intraocular Hypertension: Ibopamine Test -- Normal-Pressure Glaucoma. Vasospasm and Glaucoma -- Ocular Embryology with Special Reference to Chamber Angle Development -- The Anatomy of the Chamber Angle -- Examination of the Chamber Angle -- Normal Chamber Angle in the Adult: Gonioscopic Images -- Slit-Lamp Optical Coherence Tomography of the Anterior Segment (SL-OCT) -- The Optic Disk, Optic Nerve Head, or Papilla -- Ophthalmoscopy -- Confocal Tomography of the Optic Nerve Head, the HRT -- Heidelberg Retina Flowmeter (HRF) -- Photometry -- Physiological Concepts Related with the Visual Field -- Campimetry and Perimetry -- Campimetry and Perimetry with a Single Variable -- Campimetry and Perimetry with Two Variables: Quantitative Kinetic -- The Practice of Perimetry with the Bjerrum Screen or Goldmann Perimeter -- Static Perimetry -- Visual Field Changes in Glaucoma -- Value of the Visual Field in Clinical Glaucoma -- Static, Automated, and Computerized Perimetry -- Program for Glaucoma: G1 Visual Indices -- Value of the Computed Visual Field in Clinical Glaucoma -- Other Psychophysical Tests -- Nonconventional Perimetry -- Diagnostic and Progression Criteria: Staging of the Visual Field with Conventional and Nonconventional Perimetry -- Classification of Primary Glaucomas -- Primary Open Angle Glaucoma -- Medical Therapy in Glaucoma -- Laser Treatment in Glaucoma: General Aspects, Indication, and Different Techniques -- Glaucoma Surgery -- Angle-Closure Glaucoma -- Glaucoma and Cataract -- Glaucoma and Myopia -- Apoptosis.
- Format
- e-Book
- Location
- Online
Endoscopy in the diagnosis of small intestine diseases
https://libcat.nshealth.ca/en/permalink/provcat33809
Toshiyuki Matsui, Takayuki Matsumoto, Kunihiko Aoyagi, editors.
--Tokyo:
Springer
, c2014.
- Available Online
- View e-Book
- Location
- Online
The purpose of this book is to improve diagnostic yields of capsule endoscopy and double-balloon endoscopy, because those procedures can depict nonspecific findings that may not lead to a proper diagnosis. Another reason for the publication was recognition of the difficulty in distinguishing enteroscopic findings of ulcerative colitis from those of Crohn's disease. From a practical point of view, it is important to observe endoscopic pictures first, then to compare the images of other modalitie…
- Available Online
- View e-Book
- Other Authors
- Matsui, Toshiyuki
- Matsumoto, Takayuki
- Aoyagi, Kunihiko
- Responsibility
- Toshiyuki Matsui, Takayuki Matsumoto, Kunihiko Aoyagi, editors
- Place of Publication
- Tokyo
- Publisher
- Springer
- Date of Publication
- c2014
- Physical Description
- 1 online resource (xv, 283 pages)
- ISBN
- 9784431543527 (electronic bk.)
- 9784431543510
- Subjects (MeSH)
- Diagnosis, Differential
- Endoscopy, Gastrointestinal
- Intestinal Diseases - diagnosis - Case Reports
- Intestine, Small - pathology
- Subjects (LCSH)
- Intestine, Small - Diseases - Diagnosis
- Intestine, Small - Endoscopic surgery
- Gastroenterology
- Oncology
- Abstract
- The purpose of this book is to improve diagnostic yields of capsule endoscopy and double-balloon endoscopy, because those procedures can depict nonspecific findings that may not lead to a proper diagnosis. Another reason for the publication was recognition of the difficulty in distinguishing enteroscopic findings of ulcerative colitis from those of Crohn's disease. From a practical point of view, it is important to observe endoscopic pictures first, then to compare the images of other modalities, and finally to compare macroscopic pictures of resected specimens. For that reason, a large number of well-depicted examples of small intestinal lesions were assembled to clarify differences among small intestinal lesions that appear to exhibit similar findings and morphologies. Comparisons with radiographic findings comprise another important element in diagnosis. There are limitations in endoscopic observations of gross lesions of the small intestine, with its many convolutions. In Japan, many institutions still practice double-contrast imaging, which provides beautiful results. Because a single disorder may exhibit variations, this volume includes multiple depictions of the same disorders. Also included are lesions in active and inactive phases, as both appearances are highly likely to be encountered simultaneously in clinical practice. The number of illustrated findings therefore has been limited to strictly selected cases.
- Contents
- Part I. General Considerations -- 1. Diagnostic Process for Small Intestinal Disease -- 2. Small Intestinal Radiography -- 3. Capsule Endoscopy -- 4. Double-Balloon Endoscopy -- Part II. Specific Findings of Small Intestinal Lesions -- 5. Protruded Lesions -- 6. Submucosal Elevations -- 7. Ulcerative Lesions -- 8. Aphthous Lesions -- 9. Stenotic Lesions -- 10. Hemorrhagic Lesions -- 11. Diffuse Lesions -- 12. Reddish Lesions -- 13. Edematous Lesions -- 14. Case Presentations: Flat/Small Protrusions -- 15. Case Presentations: Depressions -- 16. Case Presentations: Protrusions of Submucosal Elevations -- 17. Case Presentations: Protrusion with Ulcer -- 18. Case Presentations: Multiple Protrusions -- 19. Case Presentations: Ulcers -- 20. Case Presentations: Stenosis -- 21. Case Presentations: Hemorrhagic Lesions -- 22. Case Presentations: Reddened Lesions -- 23. Case Presentations: Edematous Lesions -- 24. Case Presentations: Erosive Lesions -- 25. Case Presentations: Diffuse Granular or Diffuse Coarse Mucosal Lesions -- 26. Case Presentaions: Whitish Multi-nodular Lesions -- 27. Case Presentations: Intraluminal Growth -- Part III. Basic Knowledge and Classification -- 28. On Tumors -- 29. On Inflammation.
- Format
- e-Book
- Location
- Online
