paola found 24 records - Provincial Hospitals Library Catalogue

Contents: Part I. Clinical and Technical Aspects -- 1. Biomechanics of the Spine -- 2. MRI in Degenerative Disease of the Spine -- Part II. Clinical Cases.

Format: e-Book

Location: Online

MRI of rheumatic spine : a case-based atlas

https://libcat.nshealth.ca/en/permalink/provcat34030

Paola D'Aprile ; in collaboration with Alfredo Tarantino. --Cham, Switzerland: Springer , c2014.

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Location: Online

This richly illustrated and comprehensive case-based atlas documents the MR findings observed in spondyloarthritis and offers guidance on selection of the appropriate imaging protocol, which is critical in detecting the potentially very subtle changes. The presented MR study protocols include T2-weighted sequences with fat saturation and contrast-enhanced T1-weighted sequences with fat saturation, these being sequences which permit better visualization of inflammatory changes of both anterior a…

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Author: D'Aprile, Paola

Other Authors: Tarantino, Alfredo

Responsibility: Paola D'Aprile ; in collaboration with Alfredo Tarantino

Place of Publication: Cham, Switzerland

Publisher: Springer

Date of Publication: c2014

Physical Description: 1 online resource (xv, 164 pages)

ISBN: 9783319056272 (electronic bk.); 9783319056265

Subjects (MeSH): Magnetic Resonance Imaging - Atlases; Magnetic Resonance Imaging - Case Reports; Spondylitis - diagnosis - Atlases; Spondylitis - diagnosis - Case Reports

Subjects (LCSH): Spine - Diseases - Magnetic resonance imaging - Atlases; Spine - Diseases - Magnetic resonance imaging - Case studies; Rheumatism - Diagnosis - Atlases; Rheumatism - Diagnosis - Case studies; Neuroradiology; Rheumatology; Orthopedics

Abstract: This richly illustrated and comprehensive case-based atlas documents the MR findings observed in spondyloarthritis and offers guidance on selection of the appropriate imaging protocol, which is critical in detecting the potentially very subtle changes. The presented MR study protocols include T2-weighted sequences with fat saturation and contrast-enhanced T1-weighted sequences with fat saturation, these being sequences which permit better visualization of inflammatory changes of both anterior and posterior elements of the spine. Cases of spondylitis, discitis, osteoarthritis, and sacroiliitis are described, and concise information is provided on the clinical history of the rheumatic diseases. The inclusion of a large number of high-resolution images ensures that the atlas will serve as a guide to differentiation between potentially confounding diseases and an aid to early diagnosis, which has become essential with the advent of new treatments in the field of spondyloarthritis (TNF inhibitors).

Contents: Part I. Clinical and Technical Aspects -- 1. Clinical Assessment of Spondyloarthritis -- 2. MRI in Spondyloarthritis -- 3. Magnetic Resonance Technique -- 4. MR Imaging in the Follow-Up Post Therapy -- Part II. Spondyloarthritis: Clinical Cases -- Part III. Spondyloarthritis: Clinical Cases – Post-Therapy Follow-up.

Format: e-Book

Location: Online

MRI of the Rheumatic Spine : A Case-Based Atlas

https://libcat.nshealth.ca/en/permalink/provcat45112

Paola D'Aprile, Alfredo Tarantino. (Second edition) --Cham: Springer , c2020.

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Location: Online

Inflammatory pathology of the spine is an underestimated, but widespread condition among the population. This atlas shares essential information and case studies on key aspects of MRI for rheumatic inflammatory lesions of the osteoarticular structures of the spine, offering radiologists and clinicians a valuable guide to the management of patients with inflammatory back pain. In particular, this richly illustrated and comprehensive case-based atlas documents the MR findings observed in seronega…

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Author: D'Aprile, Paola

Other Authors: Tarantino, Alfredo

Responsibility: Paola D'Aprile, Alfredo Tarantino

Edition: Second edition

Place of Publication: Cham

Publisher: Springer

Date of Publication: c2020

Physical Description: 1 online resource (xvii, 206. p.) : 121 illus., 84. illus. in color

ISBN: 9783030329969; 9783030329952. (Print ed.); 9783030329976 (Print ed.); 9783030329983. (Print ed.)

Subjects (MeSH): Arthritis, Rheumatoid - diagnostic imaging; Magnetic Resonance Imaging; Spondylitis - diagnostic imaging

Specialty: Diagnostic Imaging; Orthopedics; Rheumatology

Abstract: Inflammatory pathology of the spine is an underestimated, but widespread condition among the population. This atlas shares essential information and case studies on key aspects of MRI for rheumatic inflammatory lesions of the osteoarticular structures of the spine, offering radiologists and clinicians a valuable guide to the management of patients with inflammatory back pain. In particular, this richly illustrated and comprehensive case-based atlas documents the MR findings observed in seronegative spondyloarthritis and rheumatoid arthritis of the cervical spine, providing guidelines on selecting the appropriate imaging protocol. The book is divided into two main parts, the first of which describes the general, clinical and radiological aspects of both spondyloarthritis and, as a new entry in the second edition, rheumatoid arthritis of the cervical spine. The second part then presents cases of spondylitis; discitis; facet joint and costovertebral osteoarthritis; sacroiliitis and rheumatoid arthritis of the atlanto-axial joint, including concise clinical and radiological information and a wealth of high-resolution images. The idea for a second edition of this book stemmed, on the one hand, from the global response to the first edition, and on the other, from a desire to expand the content to include wider illustrations and to address the clinically and socially relevant topic of the inflammatory pathology of the spine in more depth. The second edition offers a comprehensive guide to MRI of inflammatory diseases of the spine, facilitating an early diagnosis, which has become essential with the advent of new effective but expensive treatments with TNF inhibitors. Thanks to its “case-based” structure, the book offers an easy-to-use but thorough handbook for radiologists, neuroradiologists, rheumatologists, orthopedists and physiatrists, as well as students.

Contents: Part I. Clinical and Technical Aspects -- 1. Clinical Assessment of Rheumatoid Arthritis in Atlanto-Axial Joint -- 2. Clinical Assessment of Spondyloarthritis -- 3. MRI in Spondyloarthritis -- 4. Magnetic Resonance Technique -- 5. MR Imaging in the Follow-Up Post Therapy -- Part II. Spondyloarthritis: Clinical Cases -- Case 1. Ankylosing Spondylitis. Anterior Spondylitis -- Case 2. Ankylosing Spondylitis. Anterior Spondylitis -- Case 3. Psoriatic Arthritis. Posterior Spondylitis -- Case 4. Undifferentiated Spondyloarthritis. Spondylitis in Chronic Phase -- Case 5. Psoriatic Spondylitis. Spondylitis in Active and Inactive Phases -- Case 6. Arthritis Associated with Infl ammatory Bowel Disease -- Case 7. Juvenile Spondylitis. Spondylitis and Sacroiliitis -- Case 8. Psoriatic Arthritis. Spondylodiscitis -- Case 9. Psoriatic Arthritis. Spondylitis and Costovertebral Arthritis -- Case 10. Ankylosing Spondylitis. Spondylitis. Spondylodiscitis -- Case 11. Psoriatic Spondyloarthritis. Spondylitis. Costovertebral Arthritis -- Case 12. Psoriatic Arthritis. Spondylitis. Progression of the Disease -- Case 13. Ankylosing Spondylitis. Spondylodiscitis and Osteoarthritis -- Case 14. Arthritis Associated with Inflammatory Bowel Disease -- Case 15. Undifferentiated Spondylitis. Spondylitis in Chronic Phase -- Case 16. Psoriatic Arthritis. Anterior Spondylitis. Discitis -- Case 17. Undifferentiated Spondyloarthritis. Spondylodiscitis -- Case 18. Ankylosing Spondylitis -- Spondylodiscitis. Sacroiliitis -- Case 19. Psoriatic Arthritis. Costovertebral Arthritis and Sacroiliitis -- Case 20. Psoriatic Arthritis. Spondylitis. Discitis -- Costovertebral Arthritis. Sacroiliitis. Inflammation of Ligaments -- Case 21. Ankylosing Spondylitis. Spondylodiscitis. Sacroiliitis with Synovitis -- Case 22. Ankylosing Spondylitis. Spondylitis. Sacroiliitis -- Case 23. Ankylosing Spondylitis. Discitis. Syndesmophytes -- Case 24. Ankylosing Spondylitis. Insufficiency Fractures -- Case 25. Ankylosing Spondylitis. Active Inflammatory Lesions and Ankylosis -- Case 26. Ankylosing Spondylitis. Ankylosis -- Case 27. Psoriatic Arthritis. Costovertebral and Facet Joints Arthritis -- Case 28. Psoriatic Arthritis. Facet Joints Arthritis -- Case 29. Psoriatic Arthritis. Facet Joints Arthritis -- Case 30. Psoriatic Arthritis. Costovertebral and Facet Joints Arthritis -- Case 31. Ankylosing Spondylitis. Costovertebral and Facet Joints Arthritis -- Case 32. Psoriatic Arthritis. Costovertebral Arthritis -- Case 33. SAPHO Syndrome. Spondylitis -- Case 34. Juvenile Idiopathic Arthritis. Sacroiliitis -- Case 35. Psoriatic Arthritis. Sacroiliitis -- Case 36. Arthritis Associated with Inflammatory Bowel Disease. Sacroiliitis -- Case 37. Psoriatic Arthritis. Sacroiliitis. Enthesitis -- Case 38. Psoriatic Arthritis. Sacroiliitis -- Case 39. Ankylosing Spondylitis. Ankylosis of the Sacroiliac Joints -- Case 40. Psoriatic Arthritis. Enthesitis -- Case 41. Psoriatic Arthritis. Enthesitis -- Case 42. Ankylosing Spondylitis. Enthesitis -- Case 43. Ankylosing Spondylitis. Enthesitis -- Case 44. Differential Diagnosis. Osteochondrosis Mimicking Spondylitis -- Case 45. Differential Diagnosis. Vertebral Instability and Osteochondrosis -- Case 46. Differential Diagnosis. Osteochondrosis -- Case 47. Differential Diagnosis. Osteochondritis -- Case 48. Differential Diagnosis. Infectious Spondylitis -- Case 49. Differential Diagnosis. Septic Sacroiliitis -- Case 50. Differential Diagnosis. Bone Fracture -- Case 51. Differential Diagnosis. Bone Fracture -- Case 52. Differential Diagnosis. Osteoid Osteoma -- Case 53. Differential Diagnosis. Spondyloarthritis and Metastasis -- Part III Spondyloarthritis: Clinical Cases – Post-Therapy Follow-up -- Case 54. Psoriatic Arthritis. Spondylitis and Sacroiliitis -- Case 55. Ankylosing Spondylitis. Spondylitis in Acute and Chronic Phases -- Case 56. Psoriatic Arthritis. Sacroiliitis -- Case 57. Ankylosing Spondylitis. Spondylitis -- Case 58. Psoriatic Arthritis. Sacroiliitis -- Case 59. Ankylosing Spondylitis. Sacroiliitis -- Case 60. Ankylosing Spondylitis. Spondylodiscitis -- Case 61. Ankylosing Spondylitis. Spondylitis and Enthesitis -- Case 62. Psoriatic Arthritis. Spondylitis.

Format: e-Book

Publication Type: Atlas; Case Reports

Location: Online

Anal Fistula and Abscess

https://libcat.nshealth.ca/en/permalink/provcat47154

Carlo Ratto, Angelo Parello, Francesco Litta, Veronica De Simone, Paola Campennì [editors]. --Cham: Springer , 2020.

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Location: Online

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Other Authors: Ratto, Carlo; Parello, Angelo; Litta, Francesco; De Simone, Veronica; Campennì, Paola

Responsibility: Carlo Ratto, Angelo Parello, Francesco Litta, Veronica De Simone, Paola Campennì [editors]

Place of Publication: Cham

Publisher: Springer

Date of Publication: 2020

Physical Description: 1 online resource (x, 390 pages)

Series Title: Coloproctology

ISBN: 9783030309022

Specialty: Colorectal Surgery

Notes: "Living reference work."

Format: e-Book

Location: Online

Textbook of Primary Care Dermatology

https://libcat.nshealth.ca/en/permalink/provcat47090

David Buckley, Paola Pasquali. Springer , 2021.

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Location: Online

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Responsibility: David Buckley, Paola Pasquali

Publisher: Springer

Date of Publication: 2021

Physical Description: 1 online resource (xv, 657 pages) : illustrations

ISBN: 9783030291013

Specialty: Dermatology; Primary Health Care

Format: e-Book

Location: Online

MRI of Degenerative Disease of the Spine

https://libcat.nshealth.ca/en/permalink/provcat46972

Paola D'Aprile, Alfredo Tarantino. (Second edition) Springer , 2021.

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Location: Online

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Responsibility: Paola D'Aprile, Alfredo Tarantino

Edition: Second edition

Publisher: Springer

Date of Publication: 2021

Physical Description: 1 online resource (xv, 152 pages) : illustrations

ISBN: 9783030737078

Specialty: Neurosurgery; Radiology; Orthopedics

Format: e-Book

Location: Online

Radionuclide Imaging of Infection and Inflammation

https://libcat.nshealth.ca/en/permalink/provcat46613

Elena Lazzeri, Alberto Signore, Paola Anna Erba, Napoleone Prandini, Annibale Versari, Giovanni D´Errico, Giuliano Mariani. (Second edition) Springer , 2021.

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Location: Online

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Responsibility: Elena Lazzeri, Alberto Signore, Paola Anna Erba, Napoleone Prandini, Annibale Versari, Giovanni D´Errico, Giuliano Mariani

Edition: Second edition

Publisher: Springer

Date of Publication: 2021

Physical Description: 1 online resource (xvi, 331 pages)

ISBN: 9783030621759

Specialty: Nuclear Medicine; Radiography; Infectious Disease Medicine

Format: e-Book

Location: Online

Cryosurgery : A Practical Manual

https://libcat.nshealth.ca/en/permalink/provcat39419

Paola Pasquali, editor. --Berlin, Heidelberg: Springer , c2015.

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Location: Online

This book aims to fill the gap created by the lack of formal training in cryosurgery, which leads not only to an underutilization of the technique but also to inappropriate uses with unpleasant consequences for patients. The book covers all practical aspects of cryosurgery and also offers a theoretical foundation for practice. Basic principles, equipment, and techniques are described, and procedures are explained step by step for a range of applications, including common benign lesions, vascula…

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Other Authors: Pasquali, Paola

Responsibility: Paola Pasquali, editor

Place of Publication: Berlin, Heidelberg

Publisher: Springer

Date of Publication: c2015

Physical Description: 1 online resource (xviii, 315 p. : 264 illus., 231 illus. in color)

ISBN: 9783662439395; 9783662439388 (print ed.)

Subjects (MeSH): Cryosurgery

Abstract: This book aims to fill the gap created by the lack of formal training in cryosurgery, which leads not only to an underutilization of the technique but also to inappropriate uses with unpleasant consequences for patients. The book covers all practical aspects of cryosurgery and also offers a theoretical foundation for practice. Basic principles, equipment, and techniques are described, and procedures are explained step by step for a range of applications, including common benign lesions, vascular lesions, premalignant conditions, and malignancies. An important feature is the coverage of the latest advances in combination treatments such as topical drugs and cryosurgery, ultrasound and cryosurgery, photography and cryosurgery, cryobiopsy, and immunocryosurgery. Use of cryosurgery as palliative treatment is also discussed, and the closing chapters consider postoperative care, complications, and future directions.

Format: e-Book

Location: Online

Imaging and Pathology of Pancreatic Neoplasms : A Pictorial Atlas

https://libcat.nshealth.ca/en/permalink/provcat39522

Mirko D'Onofrio, Paola Capelli, Paolo Pederzoli, editors. --Milan: Springer , c2015.

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Location: Online

Although interest in pancreatic pathology is very high in the radiological and gastroenterological communities, it is still the case that less is known about pathology of the pancreas than about liver pathology, for example. Diagnosis depends on the structure of the pancreatic lesion, which can be directly visualized on US, CT or MR images. This atlas, which encompasses both the imaging and the pathology of pancreatic neoplasms, will therefore be invaluable in enabling radiologists and sonograp…

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Other Authors: D'Onofrio, Mirko; Capelli, Paola; Pederzoli, Paolo

Responsibility: Mirko D'Onofrio, Paola Capelli, Paolo Pederzoli, editors

Place of Publication: Milan

Publisher: Springer

Date of Publication: c2015

Physical Description: 1 online resource (xiii, 432 p. : 327 illus., 213 illus. in color)

ISBN: 9788847056787; 9788847056770 (print ed.)

Subjects (MeSH): Pancreatic Neoplasms - diagnosis; Pancreatic Neoplasms - pathology

Abstract: Although interest in pancreatic pathology is very high in the radiological and gastroenterological communities, it is still the case that less is known about pathology of the pancreas than about liver pathology, for example. Diagnosis depends on the structure of the pancreatic lesion, which can be directly visualized on US, CT or MR images. This atlas, which encompasses both the imaging and the pathology of pancreatic neoplasms, will therefore be invaluable in enabling radiologists and sonographers to understand the underlying pathology and in allowing pancreatic pathologists to understand the imaging translation. The emphasis in the atlas is very much on the pathological and imaging appearances, with most of the text concentrated at the beginning of the chapters. A comprehensive overview is provided of typical and atypical presentations and diverse aspects of common and uncommon pancreatic neoplasms, including ductal adenocarcinoma, neuroendocrine neoplasms, intraductal papillary mucinous neoplasms, cystic neoplasms, metastases and lymphoma.

Contents: Ductal Adenocarcinoma -- Neuroendocrine Neoplasms -- Intraductal Papillary Mucinous Neoplasm (IPMN) -- Serous Neoplasms -- Mucinous Neoplasms -- Solid-Pseudopapillary Neoplasms -- Secondary Tumors and Lymphoma -- Rare Neoplasms -- Driving Questions and Flow Charts -- Imaging Stigmata Review and Interpretation.

Format: e-Book

Publication Type: Atlas

Location: Online

Bones : Orthopaedic Pathologies in Roman Imperial Age

https://libcat.nshealth.ca/en/permalink/provcat39339

Andrea Piccioli, Valentina Gazzaniga, Paola Catalano ; contributors, C. Caldarini, S. Marinozzi, M.S. Spinelli, F. Zavaroni. --Cham: Springer , c2015.

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Location: Online

This book presents the results of a unique macroscopic and radiological analysis, by X-ray and CT scan, of the bone pathologies of about 1800 subjects who lived at the time of the Roman Empire (first and second centuries A.D.) and whose remains were recovered during the excavation of a suburban necropolis of Rome. The survey, which represents a collaboration between the Italian Society of Orthopaedics and Traumatology and the Special Superintendent for the Archaeological Heritage of Rome, has y…

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Author: Piccioli, Andrea

Other Authors: Gazzaniga, Valentina; Catalano, Paola

Responsibility: Andrea Piccioli, Valentina Gazzaniga, Paola Catalano ; contributors, C. Caldarini, S. Marinozzi, M.S. Spinelli, F. Zavaroni

Place of Publication: Cham

Publisher: Springer

Date of Publication: c2015

Physical Description: 1 online resource (xxi, 154 pages) : 199 illus., 141 illus. in color

ISBN: 9783319194851; 9783319194844 (print ed.)

Subjects (MeSH): Fractures, Bone - pathology; History, Ancient; Musculoskeletal Diseases - history; Musculoskeletal Diseases - pathology; Paleopathology - methods

Other Subjects: Rome

Abstract: This book presents the results of a unique macroscopic and radiological analysis, by X-ray and CT scan, of the bone pathologies of about 1800 subjects who lived at the time of the Roman Empire (first and second centuries A.D.) and whose remains were recovered during the excavation of a suburban necropolis of Rome. The survey, which represents a collaboration between the Italian Society of Orthopaedics and Traumatology and the Special Superintendent for the Archaeological Heritage of Rome, has yielded incredible images of different orthopaedic diseases in a period when no surgical treatment was available: there are cases of infection (osteomyelitis), metabolic disease (gout), hematologic disease (multiple myeloma), traumatic lesions and their complications, and degenerative pathology (osteoarthritis, particularly secondary and overload). A multidisciplinary team including orthopaedists, paleopathologists, radiologists, and medical historians has evaluated the major groups of bone disease in the population finding out incredible cases and picture of ortho-traumatologic pathologies in a pre-surgical era. The homogeneity of the sample and the number of subjects make this a study of fundamental importance.

Contents: Part I. Materials and Methods -- 1. The study of ancient bone remains -- 2. Study and data description -- Part II. Clinical Cases -- 3. Traumatic pathologies -- 4. Joint degenerative pathologies -- 5. Oncologic pathologies -- 6. Infective and metabolic diseases.

Format: e-Book

Location: Online

Skin Cancer : A Practical Approach

https://libcat.nshealth.ca/en/permalink/provcat39587

Alfonso Baldi, Paola Pasquali, Enrico P Spugnini, editors. --New York, NY: Springer New York : Imprint: Humana Press , c2014.

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Location: Online

Skin Cancer: A Practical Approach presents a comprehensive and up to date overview on skin cancer. With an emphasis on practical aspects that will set the basis for guidelines of treatment, the volume presents different diagnostic tools to help physicians obtain the proper diagnosis. Written by a worldwide base of experts selected on their recognized expertise on the different themes discussed, Skin Cancer: A Practical Approach is a valuable resource for investigators in the field of skin cance…

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Other Authors: Baldi, Alfonso; Pasquali, Paola; Spugnini, Enrico P

Responsibility: Alfonso Baldi, Paola Pasquali, Enrico P Spugnini, editors

Place of Publication: New York, NY

Publisher: Springer New York : Imprint: Humana Press

Date of Publication: c2014

Physical Description: 1 online resource (xiv, 569 p. : 270 illus., 222 illus. in color)

Series Title: Current clinical pathology

ISBN: 9781461473572; 9781461473565 (print ed.)

Subjects (MeSH): Skin Neoplasms

Abstract: Skin Cancer: A Practical Approach presents a comprehensive and up to date overview on skin cancer. With an emphasis on practical aspects that will set the basis for guidelines of treatment, the volume presents different diagnostic tools to help physicians obtain the proper diagnosis. Written by a worldwide base of experts selected on their recognized expertise on the different themes discussed, Skin Cancer: A Practical Approach is a valuable resource for investigators in the field of skin cancer, including pathologists, medical and surgical oncologists, dermatologists, general surgeons, and veterinary oncologists.

Contents: Embryology and Anatomy of the Skin -- Epidemiology And Prevention Of Cutaneous Tumors -- Cutaneous Squamous Cell Carcinoma: focus on biochemical and molecular characteristics -- Molecular Pathology Of Melanocytic Skin Cancer -- Basal Cell Carcinoma: molecular and pathological features -- Skin Adnexal tumors: a large spectrum of clinic-pathological lesions -- Pathology of Melanocytic Skin Tumors -- Pathology Of Other Skin Cancer -- Primary Cutaneous Lymphomas -- Comparative Oncology of Skin Cancer -- Clinical-pathological integration in the diagnosis of skin cancer -- Cytology -- Dermoscopy -- Introduction to Ultrasonography in Skin Cancer -- Use of 22 MHz High Frequency Ultrasound in the management of skin cancer -- Optical Coherence Tomography -- Reflectance Confocal Microscopy in Skin Cancer -- Multiphoton Laser Microscopy with Fluorescence Lifetime Imagin -- Cryosurgery -- Immunological aspects of cryosurgery -- Photodynamic Therapy -- Lasers for Skin Cancer -- Radiation therapy in Dermatology -- Electrochemotherapy in dermatological oncology -- Systemic Treatment of Primary Cutaneous Lymphomas -- Systemic therapy in melanoma -- Systemic Therapy for Rare Tumours of the Skin and Soft Tissue Tumour -- Sentinel Lymph Node -- Sunlight-Induced Skin Cancer In Companion Animals -- Telemedicine and skin cancer: Teledermatology and Teledermoscopy -- Automated Content-Based Image Retrieval: Application On Dermoscopic Images Of Pigmented Skin Lesions -- Gene Expression Profiling in Melanoma.

Format: e-Book

Location: Online

Retinopathy of Prematurity : Current Diagnosis and Management

https://libcat.nshealth.ca/en/permalink/provcat41682

Andrés Kychenthal B., Paola Dorta S., editors. --Cham: Springer , 2017.

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Location: Online

This clinically oriented book is devoted to the diagnosis and treatment of retinopathy of prematurity (ROP), a leading cause of childhood blindness. World-renowned experts in the field discuss epidemiologic and pathogenic aspects of the disease. The staging and classification of ROP are explained in detail, and guidance is provided on appropriate anesthesia. The state of the art in imaging of ROP is described and illustrated, with coverage of the advances in ophthalmic imaging technology and te…

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Other Authors: Kychenthal B., Andrés; Dorta S., Paola

Responsibility: Andrés Kychenthal B., Paola Dorta S., editors

Place of Publication: Cham

Publisher: Springer

Date of Publication: 2017

Physical Description: 1 online resource (viii, 155 pages) : 77 illus., 71 illus. in color

ISBN: 9783319521909; 9783319521886 (print ed.)

Subjects (MeSH): Retinopathy of Prematurity - diagnosis; Retinopathy of Prematurity - therapy

Abstract: This clinically oriented book is devoted to the diagnosis and treatment of retinopathy of prematurity (ROP), a leading cause of childhood blindness. World-renowned experts in the field discuss epidemiologic and pathogenic aspects of the disease. The staging and classification of ROP are explained in detail, and guidance is provided on appropriate anesthesia. The state of the art in imaging of ROP is described and illustrated, with coverage of the advances in ophthalmic imaging technology and telemedicine that have revolutionized pediatric retinal examinations and contributed significantly in elucidating the pathophysiology of ROP and improving diagnosis and treatment. Treatment indications and therapeutic alternatives, including the use of antiproliferative drugs, are addressed in separate chapters, supplying the reader with the most up-to-date knowledge in the field.

Contents: Chapter 1. Pathophysiology of ROP -- Chapter 2. Classification -- Chapter 3. Retinopathy of Prematurity Screening- Current and Future Considerations -- Chapter 4. Optical Coherence Tomography and Wide-Field Fluorescein Angiography in Retinopathy of Prematurity -- Chapter 5. Differential diagnosis of ROP -- Chapter 6. Anesthesia for New Born with Retinopathy of Prematurity: Benefits of a different technical approach -- Chapter 7. Remote Imaging and Smart Software for ROP Scanning -- Chapter 8. Photocoagulation for Retinopathy of Prematurity -- Chapter 9. Laser and Pharmacomodulation in the treatment of Retinopathy of Prematurity -- Chapter 10. Management of Stage 4 ROP -- Chapter 11. Stage 5 Retinopathy of Prematurity -- Chapter 12. Complications of Retinopathy of Prematurity Treatment -- Chapter 13. Aggressive Posterior Retinopathy of Prematurity (APROP) -- Chapter 14. Neonatologist perspective of ROP.

Format: e-Book

Location: Online

Next-Generation Therapies and Technologies for Immune-Mediated Inflammatory Diseases

https://libcat.nshealth.ca/en/permalink/provcat41415

Paola Mina-Osorio, editor. --Cham: Springer , 2017.

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Location: Online

As our understanding of immune mediated chronic inflammatory diseases (IMIDs) grows, it becomes more and more clear that these conditions result from the convergence of a multitude of pathogenic mechanisms whose relative individual contribution is different in different patient subsets. Promising new technologies have been conceived that address the hypotheses that targeting multiple pathways simultaneously, selectively delivering therapeutics to areas of inflammation and/or resetting the immun…

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Other Authors: Mina-Osorio, Paola

Responsibility: Paola Mina-Osorio, editor

Place of Publication: Cham

Publisher: Springer

Date of Publication: 2017

Physical Description: 1 online resource (xi, 202 pages) : 8 illus., 6 illus. in color

Series Title: Progress in inflammation research

ISBN: 9783319422527; 9783319422510 (print ed.)

Subjects (MeSH): Immune System Diseases - therapy; Inflammation - immunology

Abstract: As our understanding of immune mediated chronic inflammatory diseases (IMIDs) grows, it becomes more and more clear that these conditions result from the convergence of a multitude of pathogenic mechanisms whose relative individual contribution is different in different patient subsets. Promising new technologies have been conceived that address the hypotheses that targeting multiple pathways simultaneously, selectively delivering therapeutics to areas of inflammation and/or resetting the immune system, could take efficacy to new levels. However, we have long waited for the arrival of some of these technologies to the bedside, or even far enough in the drug development process in spite of the initial enthusiasm. Some of the examples covered in this book include bispecific antibodies and genomic medicines, microparticles and targeted delivery of drugs to inflamed vasculature. Most published reviews and book chapters on novel therapies for inflammatory diseases describe positive attributes of molecules or technologies under investigation and the rationale for developing them into therapeutics. The originality and potential value of this book is not in the description of these targets or technologies from the point of view of their structure or mechanism of action exclusively, but rather, in making an effort to critically address the question of what is needed to move these technologies into the clinic. Has the technology not made it past the preclinical stage and why? Has it already been tested in humans and failed? What are the potential reasons behind those failures? What do experts in each field believe can be done better to increase the probabilities of success? In addition, the authors address the competitive landscape and summarize clinical studies that have failed in the respective area. They talk about the patient populations that would be required for the successful conduction of a clinical trial to test certain molecules, and they proactively share their views regarding both the potential and the drawbacks of targets or methodologies.

Contents: Part I. Diagnosis, Patient Stratification and Biomarkers -- A Tale of Two Worlds: Pharmaceutical Investigators and Clinicians Define “Diagnosis” -- Biomarkers in Clinical Trials for Rheumatoid Arthritis -- The Role of Microparticles as Biomarkers in the Development of Therapy for Autoimmune Disease -- Part II. Genomic Medicine -- The Future for Genomic Medicine in Inflammatory Diseases -- Part III. Bispecific Antibodies -- Bispecific Antibodies -- Part IV. Cross-Functional Targets -- Targeting CD13 with Asn-Gly-Arg (NGR) Peptide-Drug Conjugates -- Energy Homeostasis of Immune Cells: Translating Cell Bioenergetics into Clinical Application in Rheumatoid Arthritis -- The Intestinal Microbiome, the Immune System and Spondyloarthropathy -- Stem Cell Therapy in the Treatment of Rheumatic Diseases and Application in the Treatment of Systemic Lupus Erythematosus.

Format: e-Book

Location: Online

Photography in Clinical Medicine

https://libcat.nshealth.ca/en/permalink/provcat46132

Paola Pasquali, editor. --Cham: Springer , c2020.

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Location: Online

This book explains how medical photography is part of the workflow in many specialties: it is needed for registries, to preserve information, for follow up, second opinion and teaching, among others. The book gathers information on this field, providing valuable practical tips for those that have never used photography for medical uses as well as those who use it regularly. Covering specialities ranging from dermatology, plastic surgery, dentistry, ophthalmology and endoscopy to forensic medici…

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Other Authors: Pasquali, Paola

Responsibility: Paola Pasquali, editor

Place of Publication: Cham

Publisher: Springer

Date of Publication: c2020

Physical Description: 1 online resource (xviii, 747 p.) : 574 illus., 456 illus. in color

ISBN: 9783030245443; 9783030245436 (Print ed.); 9783030245450 (Print ed.); 9783030245467 (Print ed.)

Subjects (MeSH): Medical Illustration; Photography - methods

Specialty: Photography

Abstract: This book explains how medical photography is part of the workflow in many specialties: it is needed for registries, to preserve information, for follow up, second opinion and teaching, among others. The book gathers information on this field, providing valuable practical tips for those that have never used photography for medical uses as well as those who use it regularly. Covering specialities ranging from dermatology, plastic surgery, dentistry, ophthalmology and endoscopy to forensic medicine, specimen photography and veterinary medicine, it highlights standardization for each procedure and relevance to ethical, patients’ perception of medical photography, cybersecurity and legal aspects. The book also presents practical sections explaining how to organize a photographic file, coding, reimbursement, compliance, use of social media and preservation as well as in depth concepts on sharp focus on blurred vision. This volume will appeal to all clinicians and practitioners interested in acquiring a high level of technical skill in medical photography.

Contents: Part I. History of Medical Photography and Its Ancestors -- 1. Medical Iconographic Representations in the Pre-photographic Era -- 2. The Dermatology Photographic Ancestors -- 3. History of Veterinary Illustration and Photography -- 4. History of Medical Photography -- Part II. Approaching the Subject -- 5. Ethical Aspects of the Use of Photography in Clinical Medicine -- 6. Treating the Patients: The Photographic Approach -- 7. Doctors as Subjects: Medical Photography as Personal Branding -- Part III. Color in Medical Photography -- 8. Understanding Color -- 9. Color Measurement and Calibration in Medical Photography -- Part IV. Basic Concepts and Equipment -- 10. Basic Photographic Concepts -- 11. Equipment and Materials for Medical Photography -- 12. Smartphones in Medical Photography -- 13. Setting Up a Photographic Medical Studio -- Part V. Standardization in Medical Specialties -- 14. Standardization in Photographic Documentation -- 15. Special Considerations: Nail Photography -- 16. Special Considerations: Hair Photography -- 17. Digital Dermoscopy Images -- 18. Total Body Photography as an Aid for the Early Detection of Skin Cancer -- 19. Photography in Plastic Surgery -- 20. Ophthalmic Photography -- 21. Clinical Dental Photography -- 22. Laboratory Imaging and Photography -- 23. Photography in Pathology and Other Procedures -- 24. Photography in Digestive Endoscopy -- 25. Forensic Photography -- 26. Veterinary Photography Nowadays -- 27. Intraoperative Photography -- Part VI. Beyond Conventional Photography -- 28. Dermatological Imaging: A Survey of Techniques -- 29. Beyond the Visible: UV, IR and Fluorescence Imaging of the Skin -- 30. Medical Thermography -- 31. 3D Photography -- 32. Focusing, Depth of Field, and Plenoptic Photography -- Part VII. Preserving, Archiving and Publishing -- 33. Metadata and DICOM for Medical Photography -- 34. Coding and Reimbursement -- 35. Digital Imaging in Dermatology: HIPAA/PHI Rules and Compliance -- 36. Cyber Security: Medical Photography and Social Media -- 37. Imaging Archives for Teaching, Learning, and Research -- 38. Submitting Images for Publication -- 39. Storing and Manipulating Images -- 40. Preservation and Conservation of Medical Photography -- Part VIII. Deep Learning and Blurred Vision -- 41. Deep Learning Performance for Triage and Diagnosis -- 42. Ophthalmic Images of Blur and Blurred Ophthalmic Images: Fuzzy Pictures in Scientific Practice -- Epilogue: The Future of Imaging.

Format: e-Book

Location: Online

Imaging spine after treatment : a case-based atlas

https://libcat.nshealth.ca/en/permalink/provcat33682

Tommaso Scarabino, Saverio Pollice, editors ; foreword by Carlo Faletti ; in collaboration with Paola D'Aprile ... [and more]. --Milan: Springer , c2014.

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Location: Online

This book reviews in detail the role of neuroradiological imaging in the evaluation of patients who have undergone surgery or interventional radiology procedures, and particularly its value in the documentation of normal and pathological post-treatment changes, detection of complications, and follow-up. The opening sections describe pretreatment images in various conditions, including trauma, degenerative disc disease, and osteoporosis, and the different types of neurosurgical and interventiona…

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Other Authors: Scarabino, T (Tommaso); Pollice, Saverio

Responsibility: Tommaso Scarabino, Saverio Pollice, editors ; foreword by Carlo Faletti ; in collaboration with Paola D'Aprile ... [and more]

Place of Publication: Milan

Publisher: Springer

Date of Publication: c2014

Physical Description: 1 online resource (xxv, 295 pages)

ISBN: 9788847053915 (electronic bk.); 9788847053908

Subjects (MeSH): Spinal Injuries - surgery; Spinal Injuries - therapy; Spine - diagnostic imaging; Treatment Outcome; Radiography

Subjects (LCSH): Spine - Imaging - Atlases; Spine - diagnosis - Atlases; Diagnostic Imaging - Atlases; Diagnostic Radiology; Interventional radiology; Neuroradiology; Neurosurgery

Abstract: This book reviews in detail the role of neuroradiological imaging in the evaluation of patients who have undergone surgery or interventional radiology procedures, and particularly its value in the documentation of normal and pathological post-treatment changes, detection of complications, and follow-up. The opening sections describe pretreatment images in various conditions, including trauma, degenerative disc disease, and osteoporosis, and the different types of neurosurgical and interventional treatment that may be used. The post-treatment appearances of normal sequelae and complications on conventional radiography, CT, and MRI are then documented in detail on the basis of a large series of clinical cases, with a wealth of images. Guidance is provided on selection of one or a combination of imaging modalities. This book will be an invaluable clinical and research tool not only for neuroradiologists but also for neurosurgeons, and interventional radiologists.

Contents: Part I. 1. Pathology -- 2. Interventional radiology -- 3. Surgery -- 4. Imaging modalities -- 5. Post-treatment imaging -- Part II. Clinical cases.

Format: e-Book

Publication Type: Atlas; Case Reports

Location: Online

Medical sciences

https://libcat.nshealth.ca/en/permalink/provcat33139

edited by Jeannette Naish and Denise Syndercombe Court. (2nd ed.) --Edinburgh, UK: Saunders Elsevier , c2015.

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Location: Online

An integrated approach to teaching basic sciences and clinical medicine has meant that medical students have been driven to a range of basic science textbooks to find relevant information. Medical Sciences is designed to do the integration for you. In just one book, the diverse branches of medical science are synthesised into the appropriate systems of the human body, making this an invaluable aid to approaching the basics of medicine within in a clinical context. Highly illustrated with clear…

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Other Authors: Naish, Jeannette; Syndercombe Court, Denise

Responsibility: edited by Jeannette Naish and Denise Syndercombe Court

Edition: 2nd ed.

Place of Publication: Edinburgh, UK

Publisher: Saunders Elsevier

Date of Publication: c2015

Physical Description: 1 online resource, 824 p.

ISBN: 9780702051388

Subjects (MeSH): Disease; Medicine - methods

Subjects (LCSH): Medicine - methods; Disease; Medical sciences - Textbooks

Abstract: An integrated approach to teaching basic sciences and clinical medicine has meant that medical students have been driven to a range of basic science textbooks to find relevant information. Medical Sciences is designed to do the integration for you. In just one book, the diverse branches of medical science are synthesised into the appropriate systems of the human body, making this an invaluable aid to approaching the basics of medicine within in a clinical context. Highly illustrated with clear, full-colour line drawings and colour photos. Information boxes throughout, giving more specific detail of research findings, drug mechanisms, etc.

Contents: Introduction and homeostasis / Jeannette Naish -- Biochemistry and cell biology / Marek H. Dominiczak -- Energy metabolism / Mark Holness, Mary Sugden, and Jeannette Naish -- Pharmacology / Walter Wieczorek and Jeannette Naish -- Human genetics / Denise Syndercombe Court and David P. Kelsell -- Pathology and immunology / Denise Syndercombe Court, Paola Domizio, Armine Sefton, and Nigel Yeatman -- Epidemiology : science for the art of medicine / Jeannette Naish and Denise Syndercombe Court -- The nervous system / Brian Pentland -- Bone, muscle, skin, and connective tissue / Lesley Robson and Denise Syndercombe Court -- Endocrinology / Joy Hinson and Peter Raven -- The cardiovascular system / Andrew Archbold and Jeannette Naish -- Haematology / Drew Provan, Adrian C. Newland, and Denise Syndercombe Court -- The respiratory system / Gavin Donaldson -- The renal system / Girish Namagondlu and Alistair Chesser -- The alimentary system / John Wilkinson -- Diet and nutrition / Amrutha Ramu, Penny Neild, and Jeannette Naish.

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Format: e-Book

Location: Online

Nuclear Medicine Textbook : Methodology and Clinical Applications

https://libcat.nshealth.ca/en/permalink/provcat44407

Duccio Volterrani, Paola Anna Erba, Ignasi Carrió, H. William Strauss, Giuliano Mariani, editors. --Cham: Springer , c2019.

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Location: Online

Building on the traditional concept of nuclear medicine, this textbook presents cutting-edge concepts of hybrid imaging and discusses the close interactions between nuclear medicine and other clinical specialties, in order to achieve the best possible outcomes for patients. Today the diagnostic applications of nuclear medicine are no longer stand-alone procedures, separate from other diagnostic imaging modalities. This is especially true for hybrid imaging guided interventional radiology or sur…

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Other Authors: Volterrani, Duccio; Erba, Paola Anna; Carrió, Ignasi; Strauss, H. William; Mariani, Giuliano

Responsibility: Duccio Volterrani, Paola Anna Erba, Ignasi Carrió, H. William Strauss, Giuliano Mariani, editors

Place of Publication: Cham

Publisher: Springer

Date of Publication: c2019

Physical Description: 1 online resource (xvi, 1331 p.) : 676 illus., 401 illus. in color

ISBN: 9783319955643; 9783319955636 (Print ed.); 9783319955650 (Print ed.)

Subjects (MeSH): Multimodal Imaging; Nuclear Medicine - methods; Radiography, Interventional; Radiopharmaceuticals - therapeutic use

Specialty: Radiography; Radiotherapy

Abstract: Building on the traditional concept of nuclear medicine, this textbook presents cutting-edge concepts of hybrid imaging and discusses the close interactions between nuclear medicine and other clinical specialties, in order to achieve the best possible outcomes for patients. Today the diagnostic applications of nuclear medicine are no longer stand-alone procedures, separate from other diagnostic imaging modalities. This is especially true for hybrid imaging guided interventional radiology or surgical procedures. Accordingly, today’s nuclear medicine specialists are actually specialists in multimodality imaging (in addition to their expertise in the diagnostic and therapeutic uses of radionuclides). This new role requires a new core curriculum for training nuclear medicine specialists. This textbook is designed to meet these new educational needs, and to prepare nuclear physicians and technologists for careers in this exciting specialty.

Contents: Part I. Basic Science -- 1. Fundamentals of Natural and Artificial Radioactivity and Interaction of Ionizing Radiations with Matter -- 2. Single-Photon-Emitting Radiopharmaceuticals -- 3. Positron-Emitting Radiopharmaceuticals -- 4. Radiopharmaceuticals for Therapy -- 5. Methods and Instrumentation for Measuring Radioactivity -- 6. General-Purpose Gamma Cameras, Dedicated Gamma Cameras, and Gamma-Probes for Radioguided Surgery -- 7. Image Acquisition and Processing with Gamma Cameras Including Integrated SPECT/CT and Dedicated Gamma Cameras -- 8. Principles of CT and MR imaging -- 9. PET/CT and PET/MR Tomographs: Image Acquisition and Processing -- 10. Essentials of Quantitative Imaging with PET -- 11. Principles of Radiation Biology and Dosimetry for Nuclear Medicine Procedures -- 12. Radiation Protection for Patients -- 13. Radiation Protection for Personnel and the Environment -- 14. Essentials of CT Image Interpretation -- 15. Essentials of MR Image Interpretation -- 16. Image-Guided and Radioguided Surgery -- Part II. Organ/Apparatus-Specific Applications -- 17. Radionuclide Imaging for Non-tumor Diseases of the Brain -- 18. Hybrid Imaging for Tumors of the Brain -- 19. Hybrid Imaging of the Head and Neck Region -- 20. Radionuclide Imaging of Cardiovascular Disease -- 21. Radionuclide Imaging of Benign Pulmonary Diseases -- 22. Hybrid Imaging for Tumours of the Chest -- 23. Hybrid Imaging for Breast Malignancies -- 24. Hybrid Imaging and Radionuclide Therapy of Musculoskeletal Diseases -- 25. Hybrid Imaging of Melanoma and Other Cutaneous Malignancies -- 26. Hybrid Imaging and Radionuclide Therapy in Hemato-oncology -- 27. Hybrid Imaging and Radionuclide Therapy for Thyroid Disorders -- 28. Hybrid Imaging in Non-thyroidal Endocrinological Disorders -- 29. Hybrid Imaging and Radionuclide Therapy of Neuroendocrine Tumors -- 30. Radionuclide Imaging of the Nephro-Urinary Tract -- 31. Functional Imaging for Benign Conditions of the Gastrointestinal Tract -- 32. Hybrid Imaging for Malignant Conditions of the Gastrointestinal Tract -- 33. Radionuclide Therapy for Tumors of the Liver and Biliary Tract -- 34. Hybrid Imaging for Gynecologic Malignancies -- 35. Hybrid Imaging for Male Malignancies -- 36. Nuclear Medicine in Pediatrics -- 37. Hybrid Imaging of the Peripheral Lymphatic System -- 38. Molecular Guidance for Planning External Beam Radiation Therapy -- Part III. Practice and Procedures (with Supplemental Online Files) -- 39. Radiopharmacy/Radiochemistry for Conventional Single-Photon Emitting and Therapeutic Radiopharmaceuticals -- 40. Radiopharmacy/Radiochemistry for Positron-Emitting Radiopharmaceuticals, Including Quality Assurance and Process Validation Principles -- 41. Recommendations for Conducting Clinical Trials with Radiopharmaceuticals -- 42. Standard Operating Procedures for Quality Control of Gamma Cameras -- 43. Standard Operating Procedures for Quality Control of PET/CT and PET/MR Tomographs -- 44. Standard Operating Procedures for Quality Control of Instrumentation for Radioguided Surgery -- 45. Technical Aspects of Dual-Energy X-Ray Absorptiometry and Quantitative Computed Tomography for Assessment of Bone Mineral Density and Body Composition -- 46. Current Practical Guidelines for the Most Common Nuclear Medicine Procedures -- 47. Teaching Cases in Nuclear Medicine: Non-oncological Applications -- 48. Teaching Cases in Nuclear Medicine: Oncological Applications -- 49. Radiological Anatomy with CT: What the Nuclear Physician Should Know When Reading a PET/CT Scan -- 50. Radiological Anatomy with MR: What the Nuclear Physician Should Know When Reading a PET/MR Scan -- 51. Interpreting and Reporting the Results of Radionuclide Tests -- Glossary.

Format: e-Book

Location: Online

Cancer immunotherapy : immune suppression and tumor growth

https://libcat.nshealth.ca/en/permalink/provcat27591

Pendergast, George C. --Amsterdam, Netherlands: Elsevier Academic Press , 2007.

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Location: Online

Available Online: View e-Book

Author: Pendergast, George C

Other Authors: Jaffee, Elizabeth M

Place of Publication: Amsterdam, Netherlands

Publisher: Elsevier Academic Press

Date of Publication: 2007

Physical Description: 409 p.

ISBN: 9780080521855

Subjects (MeSH): Antineoplastic Agents - therapeutic use; Immunotherapy; Neoplasms - therapy

Contents: Cancer immunoediting: from immune surveillance to immune escape / Ryungsa Kim -- Immunosurveillance: innate and adaptive antitumor immunity / Masahisa Jinushi and Glenn Dranoff -- Cytokine regulation of immune tolerance to tumors / Ming O. Li and Richard A. Flavell -- Immunological sculpting: natural killer cell receptors and ligands / David A. Sallman and Julie Y. Djeu -- Immune escape: immunosuppressive networks / Shuang Wei, Alfred Chang, and Weiping Zou -- Cytotoxic chemotherapy in clinical treatment of cancer / Rajesh Thirumaran, George C. Prendergast, and Paul B. Gilman -- Targeted therapeutics in cancer treatment / Colin D. Weekes and Manuel Hidalgo -- Concepts in pharmacology and toxicology / Richard A. Westhouse and Bruce D. Car -- Cancer immunotherapy: challenges and opportunities / Andrew J. Lepisto, John R. McKolanis, and Olivera J. Finn -- Cancer vaccines / Freda K. Stevenson ... [et al.] -- Immunotherapy and cancer therapeutics: why partner? / Leisha A. Emens and Elizabeth M. Jaffee -- Immune stimulatory features of classical chemotherapy / Robbert G. van der Most, Anna K. Nowak, and Richard A. Lake -- Dendritic cells and coregulatory signals: immune checkpoint blockade to stimulate immunotherapy / Drew Pardoll -- Regulatory T cells in tumor immunity: role of toll-like receptors / Rong-Fu Wang -- Tumor-associated macrophages in cancer growth and progression / Alberto Mantovani, Paola Allavena and Antonio Sica -- Tumor-associated myeloid-derived suppressor cells / Stephanie K. Bunt ... [et al.] -- Programmed death ligand-1 and galectin-1: pieces in the puzzle of tumor-immune escape / Gabriel A. Rabinovich and Thomas F. Gajewski -- Indoleamine 2,3-dioxygenase in immune escape: regulation and therapeutic inhibition / Alexander J. Muller and George C. Prendergast -- Arginase, nitric oxide synthase, and novel inhibitors of L-arginine metabolism in immune modulation / Susanna Mandruzzato, Simone Mocellin, and Vincenzo Bronte.

Format: e-Book

Location: Online

HCV Infection and Cryoglobulinemia

https://libcat.nshealth.ca/en/permalink/provcat31215

Franco Dammacco, editor. --Milan: Springer , c2012.

Available Online: View e-Book

Location: Online

In 1947, Lerner and Watson showed that the cold-precipitable proteins in serum were gammaglobulins. These "cryoglobulins" were responsible for the corresponding clinical condition "cryoglobulinemia." Meltzer and Franklin, in 1966, provided an accurate description of the typical clinical symptoms associated with cryoglobulinemia. Subsequent progress in this field was rather slow until the end of the 1980s, when cryoglobulinemia was definitively shown to be an extrahepatic manifestation of hepati…

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Other Authors: Dammacco, Franco

Responsibility: Franco Dammacco, editor

Place of Publication: Milan

Publisher: Springer

Date of Publication: c2012

Physical Description: 1 online resource (xvii, 360 p. : 64 ill., 52 ill. in color)

ISBN: 9788847017054

Subjects (MeSH): Cryoglobulinemia; Hepacivirus; Hepatitis C, Chronic; Vasculitis - pathology

Subjects (LCSH): Infectious diseases; Hematology

Abstract: In 1947, Lerner and Watson showed that the cold-precipitable proteins in serum were gammaglobulins. These "cryoglobulins" were responsible for the corresponding clinical condition "cryoglobulinemia." Meltzer and Franklin, in 1966, provided an accurate description of the typical clinical symptoms associated with cryoglobulinemia. Subsequent progress in this field was rather slow until the end of the 1980s, when cryoglobulinemia was definitively shown to be an extrahepatic manifestation of hepatitis C virus infection. The book is unique in its detailed presentation and fundamental approach. Highly qualified authors have contributed critical articles reviewing significant developments in our understanding of and therapeutic approach to HCV infection and cryoglobulinemia. The text is accompanied by striking color images and illustrations and highly informative tables. This comprehensive review of a systemic disease with a complex etiology is a valuable source of up-to-date, expert information not only for basic scientists and specialists in several disciplines but also for general practitioners as well as graduate and post-graduate students in clinical and medical research.

Contents: [Machine generated contents note] 1. Introductory Remarks / Domenico Sansonno -- Pt. I. Hepatitis C Virus Infection and the Role of the Immune System -- 2. Natural History, Pathogenesis, and Prevention of HCV Infection / Charles M. Rice -- 3. Immune Control of HCV Infection / Lynn B. Dustin -- 4. B Cell Activation: General to HCV-Specific Considerations / Claudia Brunetti -- 5. Organ-Specific Autoimmunity in HCV-Positive Patients / Fabio Presotto -- Pt. II. Cellular Compartments of HCV Infection (and Replication) -- 6. HCV and Blood Cells: How Can We Distinguish Infection from Association? / Charles M. Rice -- 7. Mechanisms of Cell Entry of Hepatitis C Virus / Vito Racanelli -- 8. HCV Infection of Hematopoietic and Immune Cell Subsets / Tomasz I. Michalak -- Pt. III. Cryoglobulinemia and the Complement System -- 9. Cryoglobulinemia and Chronic HCV Infection: An Evolving Story / Marten Trendelenburg -- 10. Complement System in Cryoglobulinemia / Marten Trendelenburg -- 11. Pivotal Role of C1qR in Mixed Cryoglobulinemia / Franco Dammacco -- Pt. IV. Structural and Genetic Features, Cytokines and Chemokines in Cryoglobulinemia -- 12. Mixed Cryoglobulinemia (MC) Cross-Reactive Idiotypes (CRI): Structural and Clinical Significance / Peter D. Gorevic -- 13. Molecular Insights into the Disease Mechanisms of Type II Mixed Cryoglobulinemia / Marica Garziera -- 14. Role of VCAM-1 in the Pathogenesis of Hepatitis-C-Associated Mixed Cryoglobulinemia Vasculitis / Gilles Kaplanski -- 15. Up-Regulation of B-Lymphocyte Stimulator (BLyS) in Patients with Mixed Cryoglobulinemia / Salvatore De Vita -- 16. Role of B-Cell-Attracting Chemokine-1 in HCV-Related Cryoglobulinemic Vasculitis / Franco Dammacco -- 17. Serum a-Chemokine CXCL10 and ß-Chemokine CCL2 Levels in HCV-Positive Cryoglobulinemia / Poupak Fallahi -- Pt. V. Clinical Manifestations of Cryoglobulinemia -- 18. Experimental Models of Mixed Cryoglobulinemia / Kelly L. Hudkins -- 19. Expanding Spectrum of Clinical Features in HCV-Related Mixed Cryoglobulinemia / Anna Linda Zignego -- 20. Classification of Cryoglobulinemic Vasculitis / Luca Quartuccio -- 21. Demographic and Survival Studies of Cryoglobulinemic Patients / Laura Castelnovo -- 22. HCV-Associated Membranoproliferative Glomerulonephritis / John Prentiss Johnson -- 23. Rheumatologic Symptoms in Patients with Mixed Cryoglobulinemia / Elisa Gremese -- 24. Endocrine Manifestations of HCV-Positive Cryoglobulinemia / Poupak Fallahi -- 25. Cutaneous Cryoglobulinemic Vasculitis / J. Andrew Carlson -- 26. Peripheral Neuropathy and Central Nervous System Involvement in Cryoglobulinemia / Sergio Ferrari -- 27. Long-Term Course of Patients with Mixed Cryoglobulinemia / Patrice P. Cacoub -- 28. HBV/HCV Co-infection and Mixed Cryoglobulinemia / Salvatore Sollima -- 29. Clinical and Immunological Features of HCV/HIV Co-infected Patients with Mixed Cryoglobulinemia / Patrice P. Cacoub -- 30. HCV-Negative Mixed Cryoglobulinemia: Facts and Fancies / Giuseppe Monti -- 31. Cryoglobulinemia in HCV-Positive Renal Transplant and Liver Transplant Patients / Nassim Kamar -- Pt. VI. HCV Infection, Cryoglobulinemia and Non-Hodgkin’s Lymphomas -- 32. Chromosome Abnormalities in HCV-Related Lymphoproliferation / Caterina Matteucci -- 33. Molecular Features of Lymphoproliferation in Mixed Cryoglobulinemia / Maria Paola Simula -- 34. Higher Prevalence of B-Cell Non-Hodgkin’s Lymphoma in HCV-Positive Patients with and Without Cryoglobulinemia / Domenico Sansonno -- 35. Incidence and Characteristics of Non-Hodgkin’s Lymphomas in HCV-Positive Patients with Mixed Cryoglobulinemia / Pietro Enrico Pioltelli -- 36. Waldenstrom’s Macroglobulinemia Associated with Cryoglobulinemia: Pathogenetic, Clinical, and Therapeutic Aspects / Efstathios Kastritis -- Pt. VII. Therapy of Cryoglobulinemia -- 37. Should HCV-Positive Asymptomatic Patients with Mixed Cryoglobulinemia Be Treated with Combined Antiviral Therapy? / Fernando Pons Renedo -- 38. Role of Rituximab in the Therapy of Mixed Cryoglobulinemia / Renato Fanin -- 39. Rituximab in Cryoglobulinemic Vasculitis: First- or Second-Line Therapy? / Paul Klenerman -- 40. PIRR Therapy in HCV-Related Mixed Cryoglobulinemia / Domenico Sansonno -- 41. Antiviral Therapy in HCV-Positive Non-Hodgkin’s Lymphoma: Pathogenetic Implications / Domenico Sansonno -- 42. Active or Indolent Cutaneous Ulcers in Cryoglobulinemia: How Should They Be Treated? / Maurizio Pietrogrande -- 43. Double Filtration Plasmapheresis: An Effective Treatment of Cryoglobulinemia / Paola Brescia -- 44. Emergency in Cryoglobulinemia: Clinical and Therapeutic Approach / Giuseppe Monti -- 45. Novel Therapeutic Approaches to Cryoglobulinemia: Imatinib, Infliximab, Bortezomib, and Beyond / Maurizio Zangari.

Format: e-Book

Location: Online

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Deep Pelvic Endometriosis : A Multidisciplinary Approach

MRI of degenerative disease of the spine : a case-based atlas