Widely used by residents, fellows, and practicing pathologists around the world, Gattuso’s Differential Diagnosis in Surgical Pathology provides a user-friendly road map to the main criteria to consider in order to differentiate between a variety of potential diagnoses that all have a very similar appearance. This comprehensive guide helps you make informed decisions for even your most complex and challenging cases, presenting a comprehensive differential diagnosis list and comparisons for eve…
Practitioners are increasingly adopting a personalised medicine approach to individually tailored patient care, especially disease diagnosis and treatment with the use of biomarkers. However, development and implementation of such approaches to chronic disease prevention need further investigation and concerted efforts for proper use in healthcare systems. This book provides high-quality, multidisciplinary knowledge from research in personalised medicine, specifically personalised prevention of…
This revised and updated new edition of a successful book is a multidisciplinary, comprehensive guide to occupational factors of malignant diseases. Building on the first edition, new research discoveries and their consequences in our understanding on carcinogenic mechanisms, diagnosis and attribution of occupational cancers are discussed. Examples of such discoveries are germline and acquired mutations of BAP1 in malignant mesothelioma, which have led to changes in diagnostic criteria, and car…
This book, now in a second revised edition, casts light on the often complex diagnosis of musculoskeletal tumors and tumor-like conditions by drawing on the experience of the Rizzoli Orthopedic Institute during more than 100 years of treatment and research in the field. The different entities are described from a multidisciplinary perspective, highlighting clinical, radiological, and histological correlations. Particular emphasis is placed on differential diagnosis, which often needs to take in…
This book has a unique focus on physiotherapy techniques and training methods that are ideally suited for the obese patient. Despite its related comorbidities and disability, not to mention its pandemic proportions, the impact of obesity on individual capacities and rehabilitative outcomes is often neglected by physiotherapists and physical trainers alike. The number of disabled subjects who are also obese is now increasing worldwide, as is the rate of obese patients admitted to post-acute reha…
This book presents the first comprehensive review of all facets of liver transplantation using DCD donors. Each of the 19 chapters are written by leading experts in the field, representing some of the most experienced DCD liver transplant programs in the world. Several topics have overlapping coverage in different chapters, providing the reader with the perspective of multiple experts on crucial topics. Chapters also highlight the steps towards building a DCD liver transplant program, the impor…
Public health policy prospectively and retrospectively addresses the consequences of events ranging from the commonplace to the catastrophic. Informing policymakers and stakeholders by enhancing their understanding of complex causation to justify remedial or precautionary actions is a critical science-policy task. In this book, the key aspects of catastrophes (regardless of their nature) and routine events are identified through a common framework for their analyses, and the analyses of the con…
This book presents the latest advances in our understanding of the pathophysiologic basis that induces the chronic positive energy balance necessary to progressively store excessive amounts of fat mass. It highlights the clinical complications of obesity, while also focusing on the major scientific advances that have highlighted the role of genetics, adipose tissue endocrinology and the environment in the mechanisms and causes of obesity. Particular attention is given to the consequences of obe…
The aim of this book is to identify and shed new light on the main surgical practices involved in acute care and trauma surgery. Adopting an evidence-based approach, a multidisciplinary team of surgeons and intensivists illustrate basic and advanced operative techniques, accompanied by a comprehensive and updated reference collection. Emerging surgical procedures in Acute Care Surgery are also explored step by step with the help of ample illustrations. Further, the book offers an overview of tr…
This book provides an innovative and comprehensive overview of the relationship between lung and exercise, both in healthy, active subjects and in subjects with chronic respiratory diseases. It investigates in detail the central role of the lungs during exercise and illustrates the impact of respiratory impairment due to both acute and chronic lung diseases on performance. Further, the book presents the latest evidence-based findings, which confirm that exercise is an effective and safe form of…
This book, written by leading international experts, describes alternate fractionation strategies in which technology-driven precise targeting and dosing allow for improved conformance and decreased volumes, with concordant lessening of toxicity, reduction in treatment time, and lower overall health care expense. The aim is to provide the advanced clinician with an up-to-date evidence-based reference that will assist in the delivery of enhanced patient care in daily practice. Traditional multi-…
This book presents the latest advances in knowledge of the pathogenesis of thyroid diseases and describes the state of the art in their diagnosis and treatment, including newly emerging management approaches. After an opening section that addresses thyroid physiology and laboratory evaluation, each of the major thyroid diseases and their subtypes is discussed, covering goiter and thyroid nodule, thyroiditis, hypothyroidism, hyperthyroidism and thyrotoxicosis, and thyroid carcinoma. Other condit…
This book aims to bring together the current research and discussions surrounding bladder cancer management. New technologies and therapeutic agents have become increasingly effective at treating urothelial bladder cancer and have created a range of opportunities to change the ways in which the disease is treated. Chapters cover the changes in adjuvant treatment, confocal laser endomicroscopy, and the roles of oncologists, pathologists, and radiotherapists in managing bladder cancer. Treating U…
This book presents state of the art knowledge on the psychopathology, clinical symptomatology, biology, and treatment of hallucinations in patients with psychoses and affective disorders. The opening section describes and examines the origins of the hallucinatory symptoms associated with schizophrenia, bipolar disorders, and drug- or substance-induced psychoses. In addition, progress in understanding of hallucinations in children and adolescents and chronic hallucinatory disorder is reviewed, a…
This book is designed to equip the reader with a detailed knowledge of the pathophysiology of chronic venous disease and an understanding of the clinical benefits of restoring venous drainage by saphenous vein-sparing procedures, including minimization of invasiveness and reduction of the recurrence rate. All of the techniques currently available for vein-sparing strategies, including novel endovenous options, are clearly described and illustrated, with explanation of the role and value of rece…
This volume provides a comprehensive review of recurrent respiratory papillomatosis and an up-to-date understanding of the etiology, pathophysiology, and management of these rare tumors caused by the human papillomavirus (HPV). The text covers the potential role of vaccines, its significant role in prevention and the controversy surrounding the use of them. Topics such as impact, quality of life, and patient advocacy are also covered and are vital to understanding the disease from the patient p…
This new atlas, the fourth of a successful series, is a completely revised and updated edition of a previously published FDG PET-CT atlas. In the past few years, considerable progress has been made in the field of PET-CT imaging, and this new edition takes full account of these recent developments. Furthermore, its educational mission has been broadened: beyond serving as a straightforward guide to FDG PET-CT imaging it now encompasses the integrative use of contrast-enhanced CT and MRI. The ne…