This book, written by leading international experts, describes alternate fractionation strategies in which technology-driven precise targeting and dosing allow for improved conformance and decreased volumes, with concordant lessening of toxicity, reduction in treatment time, and lower overall health care expense. The aim is to provide the advanced clinician with an up-to-date evidence-based reference that will assist in the delivery of enhanced patient care in daily practice. Traditional multi-…
Public health policy prospectively and retrospectively addresses the consequences of events ranging from the commonplace to the catastrophic. Informing policymakers and stakeholders by enhancing their understanding of complex causation to justify remedial or precautionary actions is a critical science-policy task. In this book, the key aspects of catastrophes (regardless of their nature) and routine events are identified through a common framework for their analyses, and the analyses of the con…
This new atlas, the fourth of a successful series, is a completely revised and updated edition of a previously published FDG PET-CT atlas. In the past few years, considerable progress has been made in the field of PET-CT imaging, and this new edition takes full account of these recent developments. Furthermore, its educational mission has been broadened: beyond serving as a straightforward guide to FDG PET-CT imaging it now encompasses the integrative use of contrast-enhanced CT and MRI. The ne…
This book provides an overview of attentional impairments in brain-damaged patients from both clinical and neuroscientific perspectives, and aims to offer a comprehensive, succinct treatment of these topics useful to both clinicians and scholars. A main focus of the book concerns left visual neglect, a dramatic but often overlooked consequence of right hemisphere damage, usually of vascular origin, but also resulting from other causes such as neurodegenerative conditions. The study of neglect o…
This volume is the first truly international text to take the practitioner from the history, the physical basis, and the rationale of brachytherapy through to the techniques, the results, and the management of complications. It is also the first truly comprehensive and complete textbook of brachytherapy. The chapters on the physics of brachytherapy and the technical planning of internal and surface radiotherapy are designed to enhance the practitioner's knowledge base and capabilities in this d…
This book provides the reader with up-to-date information on important advances in the understanding of breast cancer and innovative approaches to its management. Current and emerging perspectives on genetics, biology, and prevention are first discussed in depth, and individual sections are then devoted to pathology, imaging, oncological surgery, plastic and reconstructive surgery, medical oncology, and radiotherapy. In each case the focus is on the most recent progress and/or state of the art …
This book addresses conventional and minimally invasive surgery of the cervical spine to cater for both experts and young surgeons with less experience in this field of surgery. It is written by a group of highly trained specialists from all over the world, who present the requirements for the most advanced surgical techniques on the cervical spine. Most of the chapters concern the osteodiscoarthrosic pathology, the main condition responsible for chronic cervical and/or radicular pain. Step by …
This richly illustrated book presents a straightforward non-instrumental method of clinical facial analysis in preparation for aesthetic surgery, orthognathic surgery, and orthodontic treatments. The opening chapters discuss various practical aspects of facial examination and photography. The role of precise and standardized three-dimensional photographic documentation of the face is highlighted, and a lighting technique developed by the authors is presented. Analysis of different regions of th…
These guidelines make recommendations regarding the management of individuals with a body mass index greater than 25.0 kg/m2 and cover all age groups, from children to the elderly, as well as various patient subsets. A range of measures to yield health benefits are set out, including healthy eating plans, increased physical activity, and behavioral modifications to help patients to manage obesity. In addition, recommendations are made on the use of bariatric surgery and the new antiobesity drug…
This book provides up-to-date information on all aspects of the comorbidities that are associated with the headache disorders commonly seen in the primary care and hospital settings, including migraine, tension-type headache, and cluster headache. The coverage is wide ranging and encompasses all of the well-established comorbidities: cardio- and cerebrovascular disease, psychiatric conditions, epilepsy, sleep disorders, and various pain disorders, such as visceral pain, fibromyalgia, orofacial …
In the past two decades a number of studies have shown that abnormalities in the function and structure of coronary microcirculation can be detected in several cardiovascular diseases. On the basis of the clinical setting in which it occurs, coronary microvascular dysfunction (CMD) can be classified into four types: CMD in the absence of any other cardiac disease; CMD in myocardial diseases; CMD in obstructive epicardial coronary artery disease; and iatrogenic CMD. In some instances CMD represe…
This volume illustrates the salient aspects of cancer biology relevant to the successful implementation of immunotherapy. Topics include enhancement of antigen-specific immune responses by anti-cancer vaccines, modulation of the function of T cells within the tumor microenvironment, and the effects of genetic, epigenetic, developmental, and environmental determinants on T cell function. Other topics covered include the ex vivo expansion of T or other immune cells and their genetic modification …
This book, now in a second revised edition, casts light on the often complex diagnosis of musculoskeletal tumors and tumor-like conditions by drawing on the experience of the Rizzoli Orthopedic Institute during more than 100 years of treatment and research in the field. The different entities are described from a multidisciplinary perspective, highlighting clinical, radiological, and histological correlations. Particular emphasis is placed on differential diagnosis, which often needs to take in…
This book presents the first comprehensive review of all facets of liver transplantation using DCD donors. Each of the 19 chapters are written by leading experts in the field, representing some of the most experienced DCD liver transplant programs in the world. Several topics have overlapping coverage in different chapters, providing the reader with the perspective of multiple experts on crucial topics. Chapters also highlight the steps towards building a DCD liver transplant program, the impor…
Drug abuse and addiction are common in clinical practice. Often they interfere with patient treatment or require an alternative approach. Drug Abuse and Addiction in Medical Illness: Causes, Consequences, and Treatment is a major contribution to the literature, a gold standard title offering a comprehensive range of topics for those who care for patients with addiction, conduct research in this area, or simply have an interest in the field. Offering state-of-the-art information for all those wo…