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Extreme Hepatic Surgery and Other Strategies : Increasing Resectability in Colorectal Liver Metastases

https://libcat.nshealth.ca/en/permalink/provcat41253
Eduardo de Santibañes, Victoria Ardiles, Fernando A. Alvarez, Virginia Cano Busnelli, Martin de Santibañes, editors. --Cham: Springer , 2017.
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This book describes the diagnoses; staging and management of patients with colorectal liver metastases initially considered unresectable and portrays the different strategies to increase resectability along with their tactics and tricks. Colorectal carcinoma is the third most commonly diagnosed cancer in the world and according to recent cancer statistics around 1.23 million patients are diagnosed each year. Of these patients, approximately 50% will develop liver metastases during the course of…
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Other Authors
de Santibañes, Eduardo
Ardiles, Victoria
Alvarez, Fernando A.
Busnelli, Virginia Cano
de Santibañes, Martin
Responsibility
Eduardo de Santibañes, Victoria Ardiles, Fernando A. Alvarez, Virginia Cano Busnelli, Martin de Santibañes, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
2017
Physical Description
1 online resource (xix, 383 pages) : 170 illus., 137 illus. in color
ISBN
9783319138961
9783319138954 (print ed.)
Subjects (MeSH)
Colorectal Neoplasms - complications
Liver Neoplasms - secondary
Liver Neoplasms - surgery
Abstract
This book describes the diagnoses; staging and management of patients with colorectal liver metastases initially considered unresectable and portrays the different strategies to increase resectability along with their tactics and tricks. Colorectal carcinoma is the third most commonly diagnosed cancer in the world and according to recent cancer statistics around 1.23 million patients are diagnosed each year. Of these patients, approximately 50% will develop liver metastases during the course of their disease and around 15-25% are found to have stage IV disease at diagnosis. Liver resection has been recognized as the treatment of choice for these patients, offering overall 5-year survival rates of up to 50-60% and the only hope for cure. However, at diagnosis only 10-20% of these patients are possibly amenable to surgical resection with curative intent. The possibility to achieve an R0 resection is many times limited by the amount and quality of the future liver remnant (FLR), being posthepatectomy liver failure (PHLF) the most feared and severe complication after major liver resections. With the years, diverse strategies have been developed with the intention to increase resectability by increasing the future liver remnant and/or reducing tumor size, e.g. ALPPS. Along with these techniques, associated surgeries are developed including multivisceral resections, which broadens even more the resectability for patients.
Contents
Part I: Global Patient Evaluation and Oncological Assessment -- 1. Liver Surgical Anatomy -- 2. Resectability Assessment with Diagnostic Imaging -- 3. Preoperative Evaluation of Liver Function -- 4. Imaging-Based Preoperative Planning -- 5. Choosing the Best Strategy -- Part II: Non-operative Multimodal Therapies -- 6. Conversion and Neoadjuvant Therapies -- 7. Portal Vein Embolization -- 8. Intra-Arterial Chemotherapy -- 9. Radioembolization -- Part III: Surgical Strategies -- 10. Anesthetic Management -- 11. Intraoperative Evaluation of Resectability -- 12. Vascular Control in Major Hepatic Resections -- 13. Two-Stage Liver Surgery -- 14. Two-Stage Liver Surgery with Portal Vein Occlusion -- 15. Associating Liver Partition and Portal Vein Ligation for Staged Hepatectomy (ALPPS) -- 16. Parenchymal-Sparing Liver Resections -- 17. Combined Vascular Resections -- 18. Ex-Vivo Liver Surgery -- 19. The Role of Laparoscopy in Advanced Liver Disease -- 20. Liver Transplantation for Unresectable Disease -- Part IV: Management of Concomitant Extrahepatic Disease -- 21. Lung Metastases -- 22. Nodal Involvement -- 23. Peritoneal Metastases -- 24. Adjacent Organs Invasion: Multivisceral Resections -- Part V: Miscellany -- 25. Postoperative Complications and Their Management -- 26. Improving Quality of Life in Patients with Unresectable Disease.
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GI Surgery Annual. Volume 22

https://libcat.nshealth.ca/en/permalink/provcat41079
T.K. Chattopadhyay, editor-in-chief ; Peush Sahni, Sujoy Pal, editors. --Singapore: Springer , c2015.
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The twenty-second volume of GI Surgery Annual covers a gamut of topics from oesophageal adenocarcinoma, to motility disorders of the colon and rectum, mesenteric tumours as well as the contemporary technique of ALPPS, acute portal vein thrombosis and small for size syndrome in live donor liver transplant. The chapter on advances in gastrointestinal surgery as every year reviews the important new information in the field in an easy to understand manner.
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Other Authors
Chattopadhyay, T.K.
Sahni, Peush
Pal, Sujoy
Responsibility
T.K. Chattopadhyay, editor-in-chief ; Peush Sahni, Sujoy Pal, editors
Place of Publication
Singapore
Publisher
Springer
Date of Publication
c2015
Physical Description
1 online resource (xii, 237 p.) : 30 illus., 27 illus. in color
Series Vol.
22
Series Title
GI surgery annual
ISBN
9789811020100
9789811020094 (print ed.)
ISSN
2367-3435
Subjects (MeSH)
Digestive System Diseases
Digestive System Surgical Procedures
Gastrointestinal Diseases - surgery
Abstract
The twenty-second volume of GI Surgery Annual covers a gamut of topics from oesophageal adenocarcinoma, to motility disorders of the colon and rectum, mesenteric tumours as well as the contemporary technique of ALPPS, acute portal vein thrombosis and small for size syndrome in live donor liver transplant. The chapter on advances in gastrointestinal surgery as every year reviews the important new information in the field in an easy to understand manner.
Contents
Recent advances in oesophageal adenocarcinoma -- Motility disorders of the colon and rectum -- Screening and prevention of extra colonic cancer in hereditary non-polyposis colorectal cancer -- Complications of intestinal stomas and their management -- Mesenteric tumours -- Current concepts in bariatric surgery -- Acute portal vein thrombosis: Aetiopathogenesis, diagnosis and management -- Associated liver partition with portal vein ligation for staged hepatectomy -- Issues in management of small for size syndrome in live donor liver transplantation -- Advances in gastrointestinal surgery.
Format
e-Book
Location
Online
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Operative Techniques in Liver Resection

https://libcat.nshealth.ca/en/permalink/provcat40446
Lunan Yan, editor. (1st ed.) --Dordrecht: Springer Netherlands , c2016.
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This book presents the latest knowledge in liver resection. It includes preoperative assessment, hepatic vascular occlusion, live parenchyma transection, various liver resection techniques, liver transplantation, ex situ ex vivo resection, auto-transplantation, laparoscopic liver resection and outcome of liver resection. It describes 21 resection techniques in the same style. Each chapter is built around a series of descriptive photographs and illustrations, which are explained in detail in the…
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Other Authors
Yan, Lunan
Responsibility
Lunan Yan, editor
Edition
1st ed.
Place of Publication
Dordrecht
Publisher
Springer Netherlands
Date of Publication
c2016
Physical Description
1 online resource (xiii, 354 p. : 545 illus., 118 illus. in color)
ISBN
9789401774116
9789401774093 (print ed.)
Subjects (MeSH)
Hepatectomy - methods
Liver - surgery
Abstract
This book presents the latest knowledge in liver resection. It includes preoperative assessment, hepatic vascular occlusion, live parenchyma transection, various liver resection techniques, liver transplantation, ex situ ex vivo resection, auto-transplantation, laparoscopic liver resection and outcome of liver resection. It describes 21 resection techniques in the same style. Each chapter is built around a series of descriptive photographs and illustrations, which are explained in detail in the text. At the end of each section there are key points that are critical for surgeons performing liver resections. The authors share their extensive experience of liver resections. This book will help practitioners perform safe and expeditious resections and reduce postoperative liver failure. Hepato-biliopancreatic surgeons, hepatologists, radiologists, clinicians and researchers who are interested in liver surgery will find this book an invaluable guide. Editor Lunan Yan is a Professor and Director of the Department of Surgery, West China Hospital, Sichuan University, China.
Contents
Liver Anatomy and the History of Hepatectomy -- Anatomy in Liver Resection -- Assessment of the Patient before Liver Resection -- The Application of CT and MRI in Hepatectomy -- Liver Fibrosis and Its Assessment -- Ultrasound Elastography in the Assessment of Liver Fibrosis -- Techniques of Vascular Inflow Occlusion and Liver Parenchymal Transaction -- Hepatic Parechyma Transection Using Modern Instruction -- The Key Points of Postoperative Monitoring and Nursing Care -- Short-term Outcomes of Liver Resection -- Long-term Outcomes of Liver Resection -- Glisson's Pedicle Approach and Liver Round Ligament Approach in Anatomical Hepatectomy -- Anatomical Liver Resection -- Mesohepatectomy -- Liver resection for Primary Hepatocellular Carcinoma -- Surgical Treatment of Hepatocellular Carcinoma Accompanied With Portal Vein Tumor Thrombus -- Liver Resection of Secondary Liver Cancer -- Hepatectomy for Hepatic Hemangioma -- Liver Resection of Hepatic Hydatid Disease -- Hepatolithiasis Hepatectomy -- Liver Resection for Hilar Cholangiocarcinoma -- HepatectomyHepatectomy for gallbladder carcinoma -- Liver Resection in Pediatric Patients -- Laparoscopic Liver Resection -- Application of PVE in Hepatic Surgery -- Associating Liver Partition and Portal Vein Ligation for Staged Hepatectomy -- Pediatric Living Donor Liver Transplantation -- Right Hepatectomy with Middle hepatic vein in Living Donor -- Resection and Procurement of the Right Hemiliver in Adult-to-adult Living Donor Liver Transplantation -- Right Posterior Sector Graft for Living Donor Liver Transplantation -- Procurement of Liver Graft -- Laparoscopic Donor Liver Resection -- Native Liver Resection in Liver Transplantation -- Split Liver Transplantation and Reduced-size Liver Transplantation -- Ex vivo Liver Resection and Autotransplantation -- Vessel Exposure and Reconstruction in Liver Transplantation -- Look Forward to the Future.
Format
e-Book
Location
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Outcome prediction in cancer

https://libcat.nshealth.ca/en/permalink/provcat27210
editor, Azzam F.G. Taktak and Anthony C. Fisher. (1st ed.) --Amsterdam, Netherlands: Elsevier , 2007.
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Author
Taktak, Azzam F.G
Other Authors
Taktak, Azzam F. G
Fisher, Anthony C
Responsibility
editor, Azzam F.G. Taktak and Anthony C. Fisher
Edition
1st ed.
Place of Publication
Amsterdam, Netherlands
Publisher
Elsevier
Date of Publication
2007
Physical Description
xx, 461 p.
ISBN
6610747288 (electronic bk.)
9786610747283 (electronic bk.)
Subjects (MeSH)
Neoplasms - diagnosis
Prognosis
Contents
Cover -- Copyright page -- Foreword -- Contents -- Contributors -- Introduction -- Section 1: The Clinical Problem -- Chapter 1: The Predictive Value of Detailed Histological Staging of Surgical Resection Specimens in Oral Cancer -- 1. INTRODUCTION -- 2. PREDICTIVE FEATURES RELATED TO THE PRIMARY TUMOUR -- 3. PREDICTIVE FEATURES RELATED TO THE REGIONAL LYMPH NODES -- 4. DISTANT (SYSTEMIC) METASTASES -- 5. GENERAL PATIENT FEATURES -- 6. MOLECULAR AND BIOLOGICAL MARKERS -- 7. THE WAY AHEAD? -- REFERENCES -- Chapter 2: Survival after Treatment of Intraocular Melanoma -- 1. INTRODUCTION -- 2. INTRAOCULAR MELANOMA -- 3. STATISTICAL METHODS FOR PREDICTING METASTATIC DISEASE -- 4. PREDICTING METASTATIC DEATH WITH NEURAL NETWORKS -- 5. MISCELLANEOUS ERRORS -- 6. A NEURAL NETWORK FOR PREDICTING SURVIVAL IN UVEAL MELANOMA PATIENTS -- 7. CAVEATS REGARDING INTERPRETATION OF SURVIVAL STATISTICS -- 8. FURTHER STUDIES -- 9. CONCLUSIONS -- REFERENCES -- Chapter 3: Recent Developments in Relative Survival Analysis -- 1. INTRODUCTION -- 2. CAUSE-SPECIFIC SURVIVAL -- 3. INDEPENDENCE ASSUMPTION -- 4. EXPECTED SURVIVAL -- 5. RELATIVE SURVIVAL -- 6. POINT OF CURE -- 7. REGRESSION ANALYSIS -- 8. PERIOD ANALYSIS -- 9. AGE STANDARDIZATION -- 10. PARAMETRIC METHODS -- 11. MULTIPLE TUMOURS -- 12. CONCLUSION -- REFERENCES -- Section 2: Biological and Genetic Factors -- Chapter 4: Environmental and Genetic Risk Factors of Lung Cancer -- 1. INTRODUCTION -- 2. LUNG CANCER INCIDENCE AND MORTALITY -- 3. CONCLUSION -- REFERENCES -- Chapter 5: Chaos, Cancer, the Cellular Operating System and the Prediction of Survival in Head and Neck Cancer -- 1. INTRODUCTION -- 2. CANCER AND ITS CAUSATION -- 3. FUNDAMENTAL CELL BIOLOGY AND ONCOLOGY -- 4. A NEW DIRECTION FOR FUNDAMENTAL CELL BIOLOGY AND ONCOLOGY -- 5. COMPLEX SYSTEMS ANALYSIS AS APPLIED TO BIOLOGICAL SYSTEMS AND SURVIVAL ANALYSIS -- 6. METHODS OF ANALYSING FAILURE IN BIOLOGICAL SYSTEMS -- 7. A COMPARISON OF A NEURAL NETWORK WITH COX'S REGRESSION IN PREDICTING SURVIVAL IN OVER 800 PATIENTS -- 8. THE NEURAL NETWORK AND FUNDAMENTAL BIOLOGY AND ONCOLOGY -- 9. THE DIRECTION OF FUTURE WORK -- 10. SUMMARY -- REFERENCES -- Section 3: Mathematical Background of Prognostic Models -- Chapter 6: Flexible Hazard Modelling for Outcome Prediction in Cancer: Perspectives for the Use of Bioinformatics Knowledge -- 1. INTRODUCTION -- 2. FAILURE TIME DATA -- 3. PARTITION AND GROUPING OF FAILURE TIMES -- 4. COMPETING RISKS -- 5. GLMs AND FFANNs -- 6. APPLICATIONS TO CANCER DATA -- 7. CONCLUSIONS -- REFERENCES -- Chapter 7: Information Geometry for Survival Analysis and Feature Selection by Neural Networks -- 1. INTRODUCTION -- 2. SURVIVAL FUNCTIONS -- 3. STANDARD MODELS FOR SURVIVAL ANALYSIS -- 4. THE NEURAL NETWORK MODEL -- 5. LEARNING IN THE CPENN MODEL -- 6. THE BAYESIAN APPROACH TO MODELLING -- 7. VARIABLE SELECTION -- 8. THE LAYERED PROJECTION ALGORITHM -- 9. A SEARCH STRATEGY -- 10. EXPERIMENTS -- 11. CONCLUSION -- REFERENCES -- Chapter 8: Artificial Neural Networks Used in the Survival Analysis of Breast Cancer Patients: A Node-Negat
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e-Book
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