Locoregional Radionuclide Cancer Therapy : Clinical and Scientific Aspects
https://libcat.nshealth.ca/en/permalink/provcat46497
Franklin C.L. Wong, editor.
--Cham:
Springer
, c2021.
- Available Online
- View e-Book
- Access
- NEW Springer 2021
- Location
- Online
This book reviews locoregional radionuclide cancer therapies (LRCT). Proving an increasingly viable alternative to radiotherapy, radionuclide therapy includes a diversity of choices of well characterized biochemical and physiologic target molecules. The delivery and retention of radionuclides may be monitored by advanced imaging for exact tissue localization and for real-time dosimetry to enable personalized precision medicine. Radiopharmaceuticals in human cancer therapies are typically delive…
- Available Online
- View e-Book
- Other Authors
- Wong, Franklin C.L.
- Responsibility
- Franklin C.L. Wong, editor
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2021
- Physical Description
- 1 online resource (xii, 268 p.) : 76 illus., 56 illus. in color
- ISBN
- 9783030562670
- 9783030562663 (Print ed.)
- 9783030562687 (Print ed.)
- 9783030562694 (Print ed.)
- Subjects (MeSH)
- Neoplasms - radiotherapy
- Radiopharmaceuticals - therapeutic use
- Radiotherapy Dosage
- Radiotherapy - methods
- Specialty
- Medical Oncology
- Radiotherapy
- Abstract
- This book reviews locoregional radionuclide cancer therapies (LRCT). Proving an increasingly viable alternative to radiotherapy, radionuclide therapy includes a diversity of choices of well characterized biochemical and physiologic target molecules. The delivery and retention of radionuclides may be monitored by advanced imaging for exact tissue localization and for real-time dosimetry to enable personalized precision medicine. Radiopharmaceuticals in human cancer therapies are typically delivered in systemic routes but can also be designed for locoregional routes to harness pharmacokinetic advantages of higher payload and lower systemic toxicities. This book explores the latest advancements and clinical considerations of the locoregional approach. Throughout the chapters, the clinical and scientific bases of cancer treatment and the locoregional use of radionculides are explored. Mathematical models of radiation dosimetry of locoregional radionculdies on tissues are studied using common models for multiple commercially available radionuclides. Rodent and canine tumor models of LRCT are compared for selected radionuclides and radiopharmaceuticals. The practical aspects of radiopharmaceuticals production, marketing, transport, as well as radiation protection are reviewed. Finally, the combination of LRCT with immunotherapy and other cancer therapies and prospective future use of LRCT are discussed. This is a guide for practicing nuclear physicians, interventional radiologists, radiation oncologists, radiation scientists, veterinarians and oncologists to expand their knowledge base and to prepare for designing locoregional radionuclide cancer therapies in animals and in humans.
- Contents
- 1. Human Cancer: Epidemiology, Hallmarks, and Defense Strategies -- 2. Cancer Treatment Modalities Systemic and Locoregional Approaches: Challenges and Opportunities of Multidisciplinary Approaches -- 3. Cancer Radiotherapy: General Considerations and Human Radiobiology -- 4. Radionuclide Cancer Therapy: Unsealed Alpha- and Beta-Emitters - 5. Locoregional Therapy: Cancer Interventions with and Without Radionuclides -- 6. Radiation Dosimetry Considerations of Locoregional Radionuclide Cancer Therapy -- 7. Voxel-Based Targeted Radionuclide Therapy Dosimetry -- 8. Locoregional Unsealed Radionuclide Cancer Therapy: Experimental Findings -- 9. Animal Cancer Therapy Models: Ready Translation to Humans -- 10. An Overview of the Regulations of Radiopharmaceuticals -- 11. Locoregional Radionuclide Cancer Therapy (LRCT) Using Sealed and Unsealed Radionuclides.
- Access
- NEW Springer 2021
- Format
- e-Book
- Location
- Online
Diagnosis of Cutaneous Lymphoid Infiltrates : A Visual Approach to Differential Diagnosis and Knowledge Gaps
https://libcat.nshealth.ca/en/permalink/provcat44294
Antonio Subtil.
--Cham:
Springer
, 2019.
- Available Online
- View e-Book
- Location
- Online
This volume is the first of its kind to emphasize the visual approach in the diagnosis of cutaneous lymphoid infiltrates. Written and designed in an accessible yet highly detailed format by an expert in the field, this book bridges the knowledge gaps so often found when dealing with skin lymphomas. Complete with more than two hundred high quality images and illustrations, Diagnosis of Cutaneous Lymphoid Infiltrates offers pearls and pitfalls as well as differential diagnoses. Additionally, imag…
- Available Online
- View e-Book
- Author
- Subtil, Antonio
- Responsibility
- Antonio Subtil
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- 2019
- Physical Description
- 1 online resource (xiv, 333 p.) : 277 illus. in color
- ISBN
- 9783030116545
- 9783030116521 (Print ed.)
- 9783030116538 (Print ed.)
- Subjects (MeSH)
- Diagnosis, Differential
- Lymphoid Tissue - pathology
- Lymphoma, T-Cell, Cutaneous - diagnosis
- Specialty
- Medical Oncology
- Abstract
- This volume is the first of its kind to emphasize the visual approach in the diagnosis of cutaneous lymphoid infiltrates. Written and designed in an accessible yet highly detailed format by an expert in the field, this book bridges the knowledge gaps so often found when dealing with skin lymphomas. Complete with more than two hundred high quality images and illustrations, Diagnosis of Cutaneous Lymphoid Infiltrates offers pearls and pitfalls as well as differential diagnoses. Additionally, images are explained and decoded with the use of illustrations and analogies, proving to be an invaluable resource for pathologists, dermatologists, dermatopathologists, hematopathologists, and residents and fellows in these fields. .
- Contents
- Part I. The Basics -- Clinical Pathological Correlation -- Skin Biopsy Evaluation -- Lymphocyte Morphology -- Lymphoid Follicle Morphology and Components -- Reactive Versus Neoplastic Lymphoid Follicles -- Extrafollicular Localization of Germinal Center Cells -- Part II. Histomorphologic Differential Diagnosis (DDx) -- DDx of Epidermotropism -- DDx of Ulceration -- DDx of Perifollicular Accentuation -- DDx of Eosinophil-Rich Infiltrate -- DDx of Lymphoid Follicle Formation -- DDx of Angiocentrism -- DDx of Pannicular-based Infiltrate -- DDx of Large Cell Infiltrate -- Part III. Special Techniques -- Basic Immunohistochemistry Panels -- CD8-Positive Cutaneous Infiltrates -- Differential Diagnoses of CD30 Expression -- Differential Diagnoses of CD56 -- EBV-positive Cutaneous Infiltrates -- Differential Diagnoses of BCL2-positive follicles -- Part IV. Diagnostic Entities -- Secondary Cutaneous Invovlement by Systemic/Nodal Lymphomas -- Classic Mycosis Fungoides (MF) -- Folliculotropic Mycosis Fungoides (FMF) -- Pagetoid Reticulosis -- Granulomatous Slack Skin -- Sezary Syndrome -- Primary Cutaneous CD30+ Lymphoproliferative Disorders, Primary Cutaneous Anaplastic Large Cell Lymphoma -- Primary Cutaneous CD30+ Lymphoproliferative Disorders, Lymphomatoid Papulosis -- Primary Cutaneous CD4+ Small/Medium-Sized Pleomorphic T-Cell Lymphoproliferate Disorder -- Subcutaneous Panniculitis-like T-cell Lymphoma (alpha-beta) -- Cutaneous Gamma-Delta T-cell Lymphoma -- Primary Cutaneous Aggressive Epidermotropic CD8+ T-cell Lymphoma -- Extranodal NK/T-cell Lymphoma, Nasal Type -- Hydroa Vacciniforme-like T-cell Lymphoproliferative Disorder -- Adult T-cell Leukemia/Lymphoma (ATLL) -- Primary Cutaneous Acral CD8+ T-cell Lymphoma (Indolent DC8+ Lymphoid Proliferation of the Ear) -- Primary Cutaneous Peripheral T-cell Lymphoma, Unspecified -- Primary Cutaneous Diffuse Large B-cell Lymphoma, Leg Type -- Primary Cutaneous Diffuse Large B-cell Lymphoma, Other -- Primary Cutaneous Follicle Center Lymphoma -- Primary Cutaneous Marginal Zone B-cell Lymphoma -- Lymphomatoid Granulomatosis (LYG) -- Blastic Plasmacytoid Dendritic Cell Neoplasm -- Appendix 1. Main Immunohistochemical Stains Used in the Diagnosis of Lymphoproliferative Disorders -- Appendix 2. Genetics of Cutaneous Lymphomas -- Appendix 3. Basic Features of Cutaneous Pseudolymphomas.
- Format
- e-Book
- Publication Type
- Atlas
- Location
- Online
A Practical Guide to Skin Cancer
https://libcat.nshealth.ca/en/permalink/provcat42951
edited by Allison Hanlon.
--Cham, Switzerland:
Springer
, c2018.
- Available Online
- View e-Book
- Location
- Online
Skin cancer is the most common malignant neoplasm, and with the increasing regularity of such tumors comes the need for a practical guide for medical professionals to reference for diagnosis, management, and treatment. This book covers everything from the epidemiology of the skin cancer, clinical presentation with clinical photographs, diagrams of the most common anatomical locations, to histological descriptions, special stains/tests for diagnosis, and a treatment algorithm in chart form. A Pr…
- Available Online
- View e-Book
- Other Authors
- Hanlon, Allison
- Responsibility
- edited by Allison Hanlon
- Place of Publication
- Cham, Switzerland
- Publisher
- Springer
- Date of Publication
- c2018
- Physical Description
- 1 online resource (x, 276 p.) : 91 illus. in color
- ISBN
- 9783319749037
- 9783319749013 (print ed.)
- 9783319749020 (print ed.)
- Subjects (MeSH)
- Skin Neoplasms
- Specialty
- Dermatology
- Medical Oncology
- Abstract
- Skin cancer is the most common malignant neoplasm, and with the increasing regularity of such tumors comes the need for a practical guide for medical professionals to reference for diagnosis, management, and treatment. This book covers everything from the epidemiology of the skin cancer, clinical presentation with clinical photographs, diagrams of the most common anatomical locations, to histological descriptions, special stains/tests for diagnosis, and a treatment algorithm in chart form. A Practical Guide to Skin Cancer offers brief and succinct chapters with pertinent references, as well as high quality color photographs, diagrams, tables, and charts. Written for dermatologists, dermatology residents, and oncologists, this book allows for the reader to quickly and easily obtain the information regarding a tumor's clinical presentation, patient evaluation and treatment algorithms, proving essential for every physician who encounters these tumors in their daily practice.
- Contents
- Chapter 1. Skin Cancer: At Risk Populations and Prevention -- Chapter 2. Actinic Keratosis -- Chapter 3. Basal Cell Carcinoma -- Chapter 4. Squamous Cell Carcinoma -- Chapter 5. Melanoma in situ -- Chapter 6. Melanoma -- Chapter 7. Merkel Cell Carcinoma -- Chapter 8. Cutaneous Lymphomas -- Chapter 9. Fibrohistiocytic Skin Cancers: Dermatofibrosarcoma protuberans, Atypical Fibroxanthoma, Undifferentiatied Pleomorphic Sarcoma -- Chapter 10. Adnexal Carcinoma: Microcystic Adnexal Carcinoma and Sebaceous Carcinoma -- Chapter 11. Extramammary Paget's Disease -- Chapter 12. Procedures for the Diagnosis and Treatment of Skin Cancer.
- Format
- e-Book
- Location
- Online
Foundations of Ophthalmology : Great Insights that Established the Discipline
https://libcat.nshealth.ca/en/permalink/provcat41838
Michael F. Marmor, Daniel M. Albert, editors.
--Cham:
Springer
, 2017.
- Available Online
- View e-Book
- Location
- Online
There have been books over the years discussing the history of ophthalmology, but none that focus directly on just the most critical thinkers whose insights provided the foundation for the discipline. These men and women advanced knowledge about vision, diagnosis, disease mechanisms, and therapy through innovative thinking and perseverance against old ideas. Their stories are intriguing at a personal level and for showing the complexity of advancing medical science and, therefore, should be req…
- Available Online
- View e-Book
- Other Authors
- Marmor, Michael F
- Albert, Daniel M
- Responsibility
- Michael F. Marmor, Daniel M. Albert, editors
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- 2017
- Physical Description
- 1 online resource (x, 221 pages) : 155 illus., 55 illus. in color
- ISBN
- 9783319596419
- 9783319596402 (print ed.)
- Subjects (MeSH)
- History of Medicine
- Ophthalmology - Biography
- Ophthalmology - history
- Abstract
- There have been books over the years discussing the history of ophthalmology, but none that focus directly on just the most critical thinkers whose insights provided the foundation for the discipline. These men and women advanced knowledge about vision, diagnosis, disease mechanisms, and therapy through innovative thinking and perseverance against old ideas. Their stories are intriguing at a personal level and for showing the complexity of advancing medical science and, therefore, should be required reading for anyone practicing ophthalmology. Foundations of Ophthalmology includes giants such as Young (the nature of color and light), Braille (a practical reading system for the blind), Helmholtz (development of the ophthalmoscope), von Graefe (defining glaucoma), Curie (discovery of radiation and the basis of radiation therapy), Gonin (demonstration how to cure retinal detachment), Ridley (serendipity that led to intraocular lenses), and Kelman (development of phacoemulsification that revolutionized cataract surgery).
- Contents
- 1. Johannes Kepler and René Descartes: A Retinal Image is Transmitted to the Brain -- 2. Jacques Daviel and the Invention of Modern Cataract Surgery -- 3. John Dalton: the Recognition of Color Deficiency -- 4. Thomas Young and the Foundations of Light, Color, and Optics -- 5. Valentin Haüy and Louis Braille: Enabling Education for the Blind -- 6. Jan Evangelista Purkinje: Visual Physiologist -- 7. Franciscus Donders: The Management of Anomalies of Refraction -- 8. Hermann von Helmholtz: The Power of Ophthalmoscopy -- 9. Albrecht von Graefe: The Beginnings of Scientific Ophthalmology and Education -- 10. Karl Koller: The Introduction of Local Anesthesia -- 11. Allvar Gullstrand: Dioptrics of the Eye and the Slit Lamp -- 12. Marie Curie: Radiation as Medium That Can Cure -- 13. Jules Gonin: Proving the Cause and Cure of Retinal Detachment -- 14. Harold Ridley: The Development of a Plastic Implantable Lens -- 15. Arnall Patz and Norman Alston: Oxygen and Retinopathy of Prematurity -- 16. Charles Kelman: Phacoemulsification and Small Incision Cataract Surgery.
- Format
- e-Book
- Location
- Online
Psychotherapy for Immigrant Youth
https://libcat.nshealth.ca/en/permalink/provcat39962
Sita Patel, Daryn Reicherter, editors.
--Cham:
Springer
, c2016.
- Available Online
- View e-Book
- Location
- Online
This book provides an in-depth, practical, and cutting-edge summary of psychotherapy for immigrant children and adolescents. This text integrates practical therapeutic methods with current empirical knowledge on the unique life stressors and mental health concerns of immigrant youth, proving essential for all who seek to address the psychological needs of this vulnerable and under-served population. Specific chapters are devoted to trauma, refugees and forced displacement, cognitive-behavioral …
- Available Online
- View e-Book
- Other Authors
- Patel, Sita
- Reicherter, Daryn
- Responsibility
- Sita Patel, Daryn Reicherter, editors
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2016
- Physical Description
- 1 online resource (xvi, 203 p. : 1 illus. in color)
- ISBN
- 9783319246932
- 9783319246918 (print ed.)
- Subjects (MeSH)
- Emigrants and Immigrants
- Psychotherapy - methods
- Abstract
- This book provides an in-depth, practical, and cutting-edge summary of psychotherapy for immigrant children and adolescents. This text integrates practical therapeutic methods with current empirical knowledge on the unique life stressors and mental health concerns of immigrant youth, proving essential for all who seek to address the psychological needs of this vulnerable and under-served population. Specific chapters are devoted to trauma, refugees and forced displacement, cognitive-behavioral therapy, psychopharmacological issues, school-based treatment, family. Each chapter includes specific cultural concerns and treatment techniques for immigrant groups from various regions of the world. In-depth case examples illustrate case formulation, how and when to use specific techniques, challenges faced in the treatment of immigrant youth, and responses to common obstacles. With detailed theory and practice guidelines, Psychotherapy for Immigrant Youth is a vital resource for psychologists, psychiatrists, social workers, and other practitioners.
- Contents
- Part I. Stressors for Immigrant Youth -- Immigrant Youth Life Stressors -- Part II. Psychotherapy Interventions for Immigrant Youth -- Cognitive-Behavioral Therapy for Immigrant Youth: The Essentials -- Family Factors: Immigrant Families and Intergenerational Considerations -- School-Based Interventions -- Trauma and Acculturative Stress -- Part III. Interventions Complimentary to Psychotherapy for Immigrant Youth -- Combined Psychotherapy with Psychopharmacology -- Information Systems and Technology -- Part IV. Special Circumstances for Psychotherapy for Immigrant Youth -- Treating Forcibly Displaced Young People: Global Challenges in Mental Healthcare -- Immigrant Youth and Navigating Unique Systems That Interact with Treatment -- Erratum to -- Cultural Perspectives in the Context of Western Psychological Mind-sets: The Need for Cultural Sensitivity in the Mental Health of Immigrant Youth.
- Format
- e-Book
- Location
- Online
Orbital Tumors : Diagnosis and Treatment
https://libcat.nshealth.ca/en/permalink/provcat38955
Zeynel A. Karcioglu, editor.
(2nd ed.)
--New York, NY:
Springer
, c2015.
- Available Online
- View e-Book
- Location
- Online
Orbital Tumors, 2nd edition discusses advances in orbital disease and their treatment, offering readers an up-to-date, single volume reference for orbital tumors. Divided into two parts, this book covers everything from advances in oncogenesis and its relationship to orbital tumors, to medical genetics and the role of imaging in diagnosis of orbital tumors. Additionally, new information on incidence and behavior of tumors resulting from environmental and social trends is included. Written and e…
- Available Online
- View e-Book
- Other Authors
- Karcioglu, Zeynel A
- Responsibility
- Zeynel A. Karcioglu, editor
- Edition
- 2nd ed.
- Place of Publication
- New York, NY
- Publisher
- Springer
- Date of Publication
- c2015
- Physical Description
- 1 online resource (xvii, 516 p. : 349 illus., 221 illus. in color)
- ISBN
- 9781493915101
- 9781493915095 (print ed.)
- Subjects (MeSH)
- Orbital Neoplasms - diagnosis
- Orbital Neoplasms - therapy
- Abstract
- Orbital Tumors, 2nd edition discusses advances in orbital disease and their treatment, offering readers an up-to-date, single volume reference for orbital tumors. Divided into two parts, this book covers everything from advances in oncogenesis and its relationship to orbital tumors, to medical genetics and the role of imaging in diagnosis of orbital tumors. Additionally, new information on incidence and behavior of tumors resulting from environmental and social trends is included. Written and edited by leaders in the fields of ophthalmology and oncology, Orbital Tumors, 2nd edition builds upon the first edition, proving to be a useful reference for orbital specialists and of significant interest to everyone dealing with orbital pathology from a clinical and scientific point of view.
- Contents
- 1 Molecular Models of Cancer Development -- 2 Immune Surveillance and Cancer Pathogenesis -- 3 The Changing Nature and Behavior of Orbital Tumors – 4 Mechanisms of Tumor Metastasis in the Orbit -- 5 Second Primary Tumors in Retinoblastoma -- 6 Clinical Evaluation of the Orbit -- 7 Neuro-Ophthalmologic Evaluation of the Orbit -- 8 Ultrasonography in Orbital Differential Diagnosis -- 9 The Basics of Orbital Imaging -- 10 Imaging in Orbital Differential Diagnosis -- 11 New Concepts in Orbital Imaging -- 12 Orbital Biopsy -- 13 Orbital and Ocular Adnexal Lymphoma -- 14 Vascular Tumors -- 15 Fibrohistiocytic Tumors -- 16 Fibro-osseous and Cartilaginous Tumors and Tumor-like Conditions -- 17 Peripheral Nerve Tumors -- 18 Lacrimal Gland Tumors -- 19 Tumors of the Lacrimal Drainage System -- 20 Eyelid and Periocular Skin Tumors -- 21 Conjunctival Tumors -- 22 Ocular Tumors -- 23 Tumors of the Paranasal Sinuses, Nasal and Cranial Cavities -- 24 Metastatic Tumors -- 25 Benign Pediatric Tumors -- 26 Malignant Pediatric Tumors -- 27 Orbital Inflammation and Infection versus Neoplasia -- 28 Graves’ Disease -- 29 Mass-Forming Inflammatory Lesions of the Orbit -- 30 Orbital Cancer Staging -- 31 Surgical Treatment -- 32 3D Computer Image Analysis and Guidance for Surgical and Radiosurgical Treatment -- 33 Radiation Therapy for Orbital Tumors -- 34 Chemotherapy for Childhood Orbital Tumors -- 35 Chemotherapy for Adult Tumors -- Index.
- Format
- e-Book
- Location
- Online
