Special issues in hypertension
https://libcat.nshealth.ca/en/permalink/provcat31256
Adel E. Berbari, Giuseppe Mancia, editors.
--Milan:
Springer
, c2012.
- Available Online
- View e-Book
- Location
- Online
This volume is a cutting-edge review of the latest findings on key scientific and clinical issues in hypertension, with an integration of different new specific topics into the general knowledge of how to understand the pathophysiology and correctly diagnose and treat this chronic condition, which still represents the first cause of death in the world. Among the topics included in the book the reader will find some forms of hypertension which are frequently encountered in clinical practice and …
- Available Online
- View e-Book
- Other Authors
- Berbari, Adel E
- Mancia, Giuseppe
- Responsibility
- Adel E. Berbari, Giuseppe Mancia, editors
- Place of Publication
- Milan
- Publisher
- Springer
- Date of Publication
- c2012
- Physical Description
- 1 online resource (x, 483 p. : 69 ill.)
- ISBN
- 9788847026018
- Subjects (MeSH)
- Hypertension
- Subjects (LCSH)
- Angiography
- Cardiology
- Abstract
- This volume is a cutting-edge review of the latest findings on key scientific and clinical issues in hypertension, with an integration of different new specific topics into the general knowledge of how to understand the pathophysiology and correctly diagnose and treat this chronic condition, which still represents the first cause of death in the world. Among the topics included in the book the reader will find some forms of hypertension which are frequently encountered in clinical practice and on which new important evidence is available, such as high-normal blood pressure (also termed pre-hypertension), white-coat and masked hypertension, and high blood pressure in the elderly and the very elderly. These emerging aspects are discussed in detail, along with chapters on issues of great current interest, such as the way to assess and how to treat asymptomatic organ damage, emerging cardiovascular risk factors such as short and long-term blood pressure variability, cognitive impairment and dementia. The book also deals with the changing concepts in the management of hypertension and antihypertensive pharmacotherapy, and addresses specific topics which are rarely discussed in clinical medicine volumes, including hypertension in post-menopausal women, hormonal replacement therapy, inflammatory disorders, sexual dysfunction with treatment, and the effect of Ramadan fasting on blood pressure. This ready to hand but encompassing volume proves to be a comprehensive updating tool to professionals and clinical practitioners managing patients with hypertension.
- Contents
- 1. Prehypertension: Definition, clinical significance and therapeutic approaches: to treat or not to treat -- 2. Clinical significance and treatment requirement in white coat and masked hypertension -- 3. Resistant hypertension: epidemiologic and evolving therapeutic aspects -- 4. Primary aldosteronism: rare or common condition -- 5. Hypertension in the very elderly: special features, therapeutic approaches and problems -- 6. Clinical relevance of circadian rhythm and nocturnal dip -- 7. Morning BP surge in treated and untreated hypertensive patients: clinical relevance, prognostic significance and therapeutic approaches -- 8. Short-term and long-term BP variability -- 9. Home BP in hypertension -- 10. Obstructive sleep apnea -- 11. Hypertension, obesity and the metabolic syndrome -- 12.Salt, hypertension and cardiovascular disease -- 13. Optic fundus and retinal circulation: new technology for an old examination -- 14. Arterial stiffness as an early marker of organ damage -- 15. Central blood pressure: definition, clinical significance and therapeutic approaches -- 16. Assessment of total cardiovascular risk in Hypertension: the role of subclinical organ damage -- 17. Microcirculation in hypertension -- 18. Smoking, nicotine and BP -- 19. Inflammatory markers and other risk factors in Hypertension -- 20. Benefits: pleiotropic versus BP dependent mechanisms -- 21. Threshold and target BP values for treatment: an evolving concept -- 22. Polypill concept -- 23. J-curve phenomenon: Does it exist? -- 24. Residual risk in treated hypertension -- 25. Poor BP control in the hypertensive population: which factors are involved -- 26. Ramadan fasting and BP control -- 27. Hormone replacement therapy in postmenopausal hypertensive women -- 28. Treating pain and inflammation in hypertension -- 29. Sexual function in untreated and treated hypertension -- 30. Cognitive function and dementia in hypertension. Epidemiologic and therapeutic aspects -- 31 Is hypertension preventable? -- 32. Atrial fibrillation. Modern epidemiologic and therapeutic aspects -- 33. Genetics and hypertension. Which information for clinical practice -- 34. Dual blockade of RAAS: benefits versus adverse Outcome -- 35. Long-term effects of RAAS blockade on renal function.
- Format
- e-Book
- Location
- Online
Aging and heart failure : mechanisms and management
https://libcat.nshealth.ca/en/permalink/provcat33590
Bodh I. Jugdutt, editor.
--New York:
Springer
, c2014.
- Available Online
- View e-Book
- Location
- Online
This book synthesizes the major research advances in molecular, biochemical, and translational aspects of aging and heart failure over the last four decades and addresses future directions in management and drug discovery. It presents clinical issues and molecular mechanisms related to heart failure, including the changing demographics in the aging population with heart failure; hypertension and prevention of diastolic heart failure in the aging population; polypharmacy and adverse drug reactio…
- Available Online
- View e-Book
- Other Authors
- Jugdutt, Bodh I
- Responsibility
- Bodh I. Jugdutt, editor
- Place of Publication
- New York
- Publisher
- Springer
- Date of Publication
- c2014
- Physical Description
- 1 online resource
- ISBN
- 9781493902682 (electronic bk.)
- 9781493902675
- Subjects (MeSH)
- Aging - physiology
- Heart Failure
- Subjects (LCSH)
- Heart failure
- Older people - Medical care
- Abstract
- This book synthesizes the major research advances in molecular, biochemical, and translational aspects of aging and heart failure over the last four decades and addresses future directions in management and drug discovery. It presents clinical issues and molecular mechanisms related to heart failure, including the changing demographics in the aging population with heart failure; hypertension and prevention of diastolic heart failure in the aging population; polypharmacy and adverse drug reactions in the aging population with heart failure; changes in the heart that accompany advancing age from humans to molecules; aging-associated alterations in myocardial inflammation and fibrosis; and aging-related changes in mitochondrial function and implications for heart failure therapy. The book succinctly summarizes the large volume of data on these key topics and highlights novel pathways that need to be explored. Featuring contributions from leading clinician-scientists, Aging and Heart Failure: Mechanisms and Management is an authoritative resource on the major clinical issues in heart failure therapy in the elderly for cardiologists, gerontologists, and internists.
- Contents
- Changing Demographics of the Aging Population with Heart Failure and Implications for Therapy -- Biology of Aging and Implications for Heart Failure Therapy and Prevention -- Hypertension and Prevention of Diastolic Heart Failure in the Aging Population -- Aging and Optimal Therapy of Systolic Heart Failure in the Elderly -- Atrial Fibrillation and Heart Failure in the Aging Population -- Optimizing Therapy of Heart Failure in the Aging Population with Monitoring in Clinics -- Cardiac Alterations in Aging, Hypertension, and Diastolic Heart Failure -- Polypharmacy and Adverse Drug Reactions in the Aging Population with Heart Failure -- Age-Related Changes in Vascular Biology and Implications for Heart Failure Therapy in the Aging Population -- Biomarkers and Optimal Management of Heart Failure in the Aging Population -- Benefits of Exercise in the Elderly -- The RAAS in Heart Failure: An Update on Clinical Trials and Opportunities for Therapy -- Aging and Diastolic Dysfunction: The Interplay of Inflammation and Extracellular Matrix Regulation -- Reperfusion and Vasodilator Therapy in Elderly Patients with STEMI and Heart Failure: Improving Outcomes -- Erythropoietin Therapy for Heart Failure -- Role of Resistin in Heart Failure in the Elderly -- Role of Coronary Artery Calcium in Cardiovascular Risk Stratification and Management in the Aging Population -- Aging and Remodeling of the RAS and RAAS and Related Pathways: Implications for Heart Failure Therapy -- Aging and Right Ventricular Failure from Pulmonary Hypertension: Effect of Right Ventricular and Pulmonary Artery Remodeling -- Aging and Right Ventricular Failure from Pulmonary Hypertension: Effect of Right Ventricular and Pulmonary Artery Remodeling -- Biomarkers of Cardiovascular Aging -- Changes in the Heart That Accompany Advancing Age: Humans to Molecules -- Aging-Related Changes in Cell Death and Cell Survival Pathways and Implications for Heart Failure Therapy -- Aging-Related Changes in Telomeres and Telomerases and Implications for Heart Failure Therapy -- Aging-Associated Alterations in Myocardial Inflammation and Fibrosis: Pathophysiological Perspectives and Clinical Implications -- Aging-Related Changes in Extracellular Matrix: Implications for Ventricular Remodeling Following Myocardial Infarction -- Calcium-Handling Defects and Changes in Cardiac Function in the Aging Heart -- Integrins: Implications for Aging in Heart Failure Therapy -- Adipokines as Novel Biomarkers in Aging and Heart Failure -- Aging-Related Changes in Cellular and Molecular Mechanisms of Postinfarction Remodeling: Implications for Heart Failure Therapy -- Aging-Related Changes in Mitochondrial Function and Implication for Heart Failure Therapy -- Regulation of SERCA Via Oxidative Modifications: Implications for the Pathophysiology of Diastolic Dysfunction in the Aging Heart -- SMP30 and Aging-Related Cardiac Remodeling and Heart Failure.
- Format
- e-Book
- Location
- Online
Chronic Kidney Disease and Hypertension
https://libcat.nshealth.ca/en/permalink/provcat38992
Matthew R. Weir, Edgar V. Lerma, editors.
--New York, NY:
Springer New York : Imprint: Humana Press
, c2015.
- Available Online
- View e-Book
- Location
- Online
The treatment of hypertension has become the most important intervention in the management of all forms of chronic kidney disease. Chronic Kidney Disease and Hypertension is a current, concise, and practical guide to the identification, treatment and management of hypertension in patients with chronic kidney disease. In depth chapters discuss many relevant clinical questions and the future of treatment through medications and or novel new devices. Written by expert authors, Chronic Kidney Disea…
- Available Online
- View e-Book
- Other Authors
- Weir, Matthew R
- Lerma, Edgar V
- Responsibility
- Matthew R. Weir, Edgar V. Lerma, editors
- Place of Publication
- New York, NY
- Publisher
- Springer New York : Imprint: Humana Press
- Date of Publication
- c2015
- Physical Description
- 1 online resource (xiii, 257 p. : 40 illus., 19 illus. in color)
- Series Title
- Clinical hypertension and vascular diseases
- ISBN
- 9781493919826
- 9781493919819 (print ed.)
- Abstract
- The treatment of hypertension has become the most important intervention in the management of all forms of chronic kidney disease. Chronic Kidney Disease and Hypertension is a current, concise, and practical guide to the identification, treatment and management of hypertension in patients with chronic kidney disease. In depth chapters discuss many relevant clinical questions and the future of treatment through medications and or novel new devices. Written by expert authors, Chronic Kidney Disease and Hypertension provides an up-to-date perspective on management and treatment and how it may re-shape practice approaches tomorrow.
- Contents
- Changes in Guideline Trends and Applications in Practice: JNC 2013 and the future -- Central BP monitoring, Home BP Monitoring, Ambulatory BP Monitoring in CKD -- Resistant hypertension in patients with chronic kidney disease -- Neurogenic Factors In Hypertension Associated With Chronic Kidney Disease -- Novel Molecules -- Dual Inhibitors: RAAS Blockers/Combination Therapies: What Do All These Trials Mean? -- Renal Sympathetic Denervation -- Novel baroreceptor activation therapy -- Blood Pressure Vaccines -- Masked Hypertension: Does it Lead to CVD or CKD? -- White Coat Hypertension: Do We Really Understand It Now? -- Uric Acid And Hypertension: Is There Really A Link? -- Preeclampsia: Angiogenic factors, blood pressure, and the kidney -- Inflammation and Hypertension -- Genome-Wide Association Studies (Gwas) Of Blood Pressure In Different Populations -- Endocrine Hypertension and Chronic Kidney Disease -- Hypertension in Children with Chronic Kidney Disease -- Obesity/OSA/Metabolic syndrome in pts with CKD and hypertension: the missing link.
- Format
- e-Book
- Location
- Online
Hypertension and Renal Organ Damage
https://libcat.nshealth.ca/en/permalink/provcat42762
Roberto Pontremoli.
--Cham:
Springer
, c2018.
- Available Online
- View e-Book
- Location
- Online
This book guides readers through a wide spectrum of clinical presentations in patients with arterial hypertension and different degrees of renal impairment, ranging from asymptomatic urine abnormalities to end stage renal disease. On the basis of six case studies, the author reviews and discusses current guidelines and recommendations aimed at optimizing the diagnostic and therapeutic approach both to renal and cardiovascular risk in commonly encountered real-world clinical scenarios including …
- Available Online
- View e-Book
- Author
- Pontremoli, Roberto
- Responsibility
- Roberto Pontremoli
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2018
- Physical Description
- 1 online resource (xiii, 75 p.) : 25 illus., 23 illus. in color
- Series Title
- Practical case studies in hypertension management
- ISBN
- 9783319564081
- 9783319564074 (print ed.)
- 9783319564098 (print ed.)
- ISSN
- 2364-6632
- Subjects (MeSH)
- Hypertension - complications
- Kidney Diseases
- Urination Disorders
- Specialty
- Cardiology
- Nephrology
- Abstract
- This book guides readers through a wide spectrum of clinical presentations in patients with arterial hypertension and different degrees of renal impairment, ranging from asymptomatic urine abnormalities to end stage renal disease. On the basis of six case studies, the author reviews and discusses current guidelines and recommendations aimed at optimizing the diagnostic and therapeutic approach both to renal and cardiovascular risk in commonly encountered real-world clinical scenarios including challenging cases of diabetic kidney disease, ischemic nephropathy and resistant hypertension. It also explores anti-hypertensive drug combinations, including single or multiple RAAS-I, lipid lowering and antiplatelet drugs, as well as the appropriate use of glucose lowering drugs in the context of chronic kidney disease. This handy and practical book provides physicians in the area of general and internal medicine, as well as specialists in the cardiovascular, metabolic and renal fields valuable insights into optimal therapeutic targets for blood pressure and glucose control in renal patients.
- Contents
- Clinical Case 1. Patient with Hypertension and Reduced Glomerular Filtration Rate -- Clinical Case 2. Patient with Hypertension and Microalbuminuria -- Clinical Case 3. Patient with Hypertension and Mild Proteinuria -- Clinical Case 4. Patient with Hypertension and Overt Proteinuria -- Clinical Case 5. Patient with Hypertension and End-Stage Renal Disease -- Clinical Case 6. Patient with Hypertension on Dialysis.
- Format
- e-Book
- Location
- Online
ACEi and ARBS in Hypertension and Heart Failure
https://libcat.nshealth.ca/en/permalink/provcat39106
Pasquale Perrone Filardi, editor.
--Cham:
Springer International Publishing : Imprint: Springer ; ISCP
, c2015.
- Available Online
- View e-Book
- Location
- Online
This book summarizes how the renin angiotensin system is implicated in the progression of atherosclerotic disease as well as of left ventricular dysfunction and reviews the action of angiotensin converting enzyme inhibitors and AT1 receptor antagonists on reducing morbidity and mortality in patients with left ventricular dysfunction or in those at high cardiovascular risk with preserved ventricular function. ACEi and ARBS in Hypertension and Heart Failure is a highly practical reference reviewi…
- Available Online
- View e-Book
- Other Authors
- Perrone Filardi, Pasquale
- Other Authors
- International Society of Cardiovascular Pharmacotherapy
- Responsibility
- Pasquale Perrone Filardi, editor
- Alternate Title
- Angiotensin converting enzyme inhibitors and angiotensin II receptor blockers in hypertension and heart failure
- Place of Publication
- Cham
- Publisher
- Springer International Publishing : Imprint: Springer ; ISCP
- Date of Publication
- c2015
- Physical Description
- 1 online resource (x, 150 p. : 19 illus., 13 illus. in color)
- Series Title
- Current cardiovascular therapy
- ISBN
- 9783319097886
- 9783319097879 (print ed.)
- Subjects (MeSH)
- Angiotensin II Type 1 Receptor Blockers
- Angiotensin-Converting Enzyme Inhibitors - pharmacology
- Heart Failure - drug therapy
- Hypertension - drug therapy
- Renin-Angiotensin System
- Abstract
- This book summarizes how the renin angiotensin system is implicated in the progression of atherosclerotic disease as well as of left ventricular dysfunction and reviews the action of angiotensin converting enzyme inhibitors and AT1 receptor antagonists on reducing morbidity and mortality in patients with left ventricular dysfunction or in those at high cardiovascular risk with preserved ventricular function. ACEi and ARBS in Hypertension and Heart Failure is a highly practical reference reviewing the evidence and providing a rationale for the appropriate use of RAS antagonists in cardiovascular diseases. It is written in an easy-to-follow format and with many illustrations to aid clarity and the assimilation of information. Each chapter is written by established authorities in their fields who are also experienced in explaining often complex concepts. The result is a unique book which is not only comprehensive but also clear and useful for the busy medical practitioner.
- Contents
- 1. Angiotensin Converting Enzyme Inhibitors and AT1 Antagonists for Treatment of Hypertension -- 2. ACE Inhibitor and Renin–Angiotensin System the Cornerstone of Therapy for Systolic Heart Failure -- 3. Impact of Chronic Kidney Disease and Diabetes Mellitus on Choice of Renin Angiotensin System: Inhibitors in Patients with Hypertension and Heart Failure -- 4. Target Organ Damage and RAAS Blockade.
- Format
- e-Book
- Location
- Online
The Local Cardiac Renin-Angiotensin Aldosterone System
https://libcat.nshealth.ca/en/permalink/provcat29683
Edward D. Frohlich, Richard N. Re, editors.
(2nd ed.)
--Boston, MA:
Springer-Verlag US
, c2009.
- Available Online
- View e-Book
- Location
- Online
How exciting it is to see a field so well established as the ren- angiotensin system continue to grow and mature. Originally, following the original identification of renin by Tigerstedt and Bergman over 100 years ago, workers in this area spent years attempting to establish its role in experimental and renal hypertension. The early work by Goldblatt, in 1934, demonstrated that the placement of a clip around a renal artery was clearly related to the subsequent development of hypertension. Howev…
- Available Online
- View e-Book
- Author
- Frohlich, Edward D
- Other Authors
- International Workshop on the Local Cardiac Renin Angiotensin Aldosterone System (3rd : 2008 : New Orleans, La.)
- Other Authors
- Re, Richard N
- Responsibility
- Edward D. Frohlich, Richard N. Re, editors
- Edition
- 2nd ed.
- Place of Publication
- Boston, MA
- Publisher
- Springer-Verlag US
- Date of Publication
- c2009
- ISBN
- 9781441905284
- Subjects (MeSH)
- Cardiology - Congresses
- Hypertension - metabolism
- Receptors, Cell Surface - physiology
- Renin-Angiotensin System - physiology
- Vacuolar Proton-Translocating ATPases - metabolism
- Subjects (LCSH)
- Cardiology
- Physiology
- Abstract
- How exciting it is to see a field so well established as the ren- angiotensin system continue to grow and mature. Originally, following the original identification of renin by Tigerstedt and Bergman over 100 years ago, workers in this area spent years attempting to establish its role in experimental and renal hypertension. The early work by Goldblatt, in 1934, demonstrated that the placement of a clip around a renal artery was clearly related to the subsequent development of hypertension. However, it wasn't until the simultaneous finding by two different geographically separated teams, Page, et al, in the United States and Braun-Menendez, et al, in Argentina that the peptide angiotensin was identified. Thus, the rate-limiting enzyme renin was released from the kidney and catalyzed a biochemical cascade which was eventually shown to produce the elevated arterial pressure. Subsequently, many workers contributed to the elucidation of the concept and sequence of angiotensin I1 generation. Thus, the enzyme renin acted upon its protein substrate, produced in the liver, to liberate the decapeptide angiotensin I which, upon circulating through the pulmonary circulation, finally produced the potent octapeptide angiotensin. Several important subsequent findings demonstrated that angiotensin I1 promoted the release of the adrenal corticosteroid from that gland, thereby resulting in a larger system, the renin-angiotensin-aldosterone system. Further, this system demonstrated a classical biofeedback and the circulating octapeptide was shown to have additional biological activities in organs other than heart, vessels, kidney, adrenals, and even brain.
- Contents
- 1. Are Local Renin–Angiotensin Systems the Focal Points for Understanding Salt Sensitivity in Hypertension? -- 2. Newer Insights into the Biochemical Physiology of the Renin–Angiotensin System: Role of Angiotensin-(1-7), Angiotensin Converting Enzyme 2, and Angiotensin-(1-12) -- 3. Renin, Prorenin, and the (Pro)renin Receptor -- 4. Intracellular Accumulation and Nuclear Trafficking of Angiotensin II and the Angiotensin II Type 1 Receptor -- 5. Pathophysiologic Implications of Cell Swelling in the Failing Heart: Influence of Intracrine and Extracellular Renin–Angiotensin Systems -- 6. Exploiting Rat Genetics to Investigate Hypertensive End-Organ Damage -- 7. Alternative Renin Transcripts and Functions of Cytoplasmatic Renin -- 8. Novel Aspects of the Cardiac Renin–Angiotensin System -- 9. Intracrine Function from Angiotensin to Stem Cells -- 10. Renin Cell Identity and Homeostasis -- 11. Role of Renal Aminopeptidases and Angiotensin Type-2 (AT2) Receptors in Sodium Excretion and Hypertension -- 12. Intrarenal Angiotensin II Augmentation in Hypertension -- 13. Collecting Duct Renin: A Critical Link in Angiotensin II-Dependent Hypertension -- 14. Renin–Angiotensin–Aldosterone System and Cardiomyocyte Apoptosis in Hypertensive Heart Disease -- 15. Upregulation of Angiotensin II Type 2 Receptor (agtr2) Attenuates Atherosclerotic Lesion Formation and Enhances Apoptosis in the LDL Receptor Knockout Mice Fed High Cholesterol Diet -- 16. Salt and Heart: RAAS Involvement -- 17. Cardiac Effects of Aldosterone, the Bad, but Is There Also a Good?
- Format
- e-Book
- Location
- Online
