Nova Scotia Health Authority. QEII. Diagnostic Imaging.
Halifax, NS:
Nova Scotia Health Authority
, 2018.
- Pamphlet Number
- 0425
- Available Online
- View Pamphlet
A bone scan is done in the Nuclear Medicine Department. A very small, safe amount of radioactive material (radioisotope) is given. The dosage of the radioactive material is so small that it will not harm you. A gamma camera is used to take pictures. Getting ready for the test (what to wear and bring) is outlined. The steps of the test are provided. If you are unable to keep your appointment, please call immediately so that another patient can be booked. The French version of this pamphlet 1956,…
- Available Online
- View Pamphlet
- Corporate Author
- Nova Scotia Health Authority. QEII. Diagnostic Imaging
- Alternate Title
- Scintigraphy - bone
- Place of Publication
- Halifax, NS
- Publisher
- Nova Scotia Health Authority
- Date of Publication
- 2018
- Format
- Pamphlet
- Language
- English
- Physical Description
- 1 electronic document ([4] p.) : digital, PDF file
- Subjects (LCSH)
- Diagnostic imaging
- Radioisotope scanning
- Abstract
- A bone scan is done in the Nuclear Medicine Department. A very small, safe amount of radioactive material (radioisotope) is given. The dosage of the radioactive material is so small that it will not harm you. A gamma camera is used to take pictures. Getting ready for the test (what to wear and bring) is outlined. The steps of the test are provided. If you are unable to keep your appointment, please call immediately so that another patient can be booked. The French version of this pamphlet 1956, "Scintigraphie osseuse", is also available.
- Responsibility
- Prepared by: Diagnostic Imaging
- Pamphlet Number
- 0425
Clinical Applications of Nuclear Medicine Targeted Therapy
https://libcat.nshealth.ca/en/permalink/provcat42889
edited by Emilio Bombardieri, Ettore Seregni, Laura Evangelista, Carlo Chiesa, Arturo Chiti.
--Cham:
Springer
, c2018.
- Available Online
- View e-Book
- Location
- Online
This book offers a practical and modern update on radioisotope therapy. Clinically oriented, it provides a thorough guide to patient management, with the latest indications and procedures for the current radioisotopic treatments. It addresses the clinical problems associated with each respective pathology, discussing the management of patients (diagnosis and non-radioisotope therapy), the radiopharmaceuticals available today, and the current radioisotopic procedures. Wherever possible, informat…
- Available Online
- View e-Book
- Responsibility
- edited by Emilio Bombardieri, Ettore Seregni, Laura Evangelista, Carlo Chiesa, Arturo Chiti
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2018
- Physical Description
- 1 online resource (xiv, 503 p.) : 108 illus., 73 illus. in color
- ISBN
- 9783319630670
- 9783319630663 (print ed.)
- 9783319630687 (print ed.)
- Subjects (MeSH)
- Nuclear Medicine - methods
- Radioisotopes - therapeutic use
- Radiopharmaceuticals - therapeutic use
- Radiotherapy - methods
- Specialty
- Radiotherapy
- Abstract
- This book offers a practical and modern update on radioisotope therapy. Clinically oriented, it provides a thorough guide to patient management, with the latest indications and procedures for the current radioisotopic treatments. It addresses the clinical problems associated with each respective pathology, discussing the management of patients (diagnosis and non-radioisotope therapy), the radiopharmaceuticals available today, and the current radioisotopic procedures. Wherever possible, information on dosimetry is included at the end of each topic, together with a list of and comments on the most recent guidelines with their recommendations for radiometabolic therapy. The book is divided into six main sections: thyroid diseases, hepatic tumors (HCC and hepatic metastases), bone metastases from prostate cancer, lymphomas, and neuroendocrine tumors. The last section is dedicated to new perspectives of radioisotope treatment. Based on contributions from of a multidisciplinary team of specialists: oncologists, surgeons, endocrinologists, hematologists, urologists, radiopharmacists and nuclear medicine physicians, it provides a comprehensive analysis of the position of radioisotope treatments among the various therapeutic options. Readers interested in targeted therapy, radiometabolic therapy, radioimmunotherapy and radiometabolic imaging will find this book both informative and insightful.
- Contents
- THYROID DISEASES -- Diagnosis and treatment of hyperthyroidism (Endocrinologist) -- Radiopharmaceuticals for therapy of thyroid diseases ( chemistry, mechanism of uptake, biodistribution, doses) (Radiochemist) -- Radioiodine therapy of hyperthyroidism (indications , procedures and results) ( Nucl Medicine Physician) -- Dosimetry (Physicist) -- Clinical management of thyroid cancer (Oncologist) -- Radioidine therapy of thyroid cancer (ablation, loco-regional and distant metastases, indications procedures and results) (Nucl Medicine Physician) -- Dosimetry (Physicist) -- Novel approaches of radiometabolic treatment of thyroid cancer (Nucl Medicine Physician) -- Published guidelines on radioisotopic treatments of thyroid diseases (Nucl Medicine Physician and Oncologist) -- HEPATIC CANCER -- Clinical options for treatment of hepatocellular carcinoma (HCC) (Oncologist, Surge on) -- Radiopharmaceuticals for radioembolization (characteristics, mechanism of uptake, biodistribution, doses) (Radiochemist) -- HCC radioembolization with 90Y microspheres (indications and procedures) (Nucl Medicine Physician) -- Dosimetry (Physicist) -- The clinical problem of hepatic metastases (Oncologist, Surgeon) -- Radioembolization of hepatic metastases with 90Y microspheres (indications and procedures) (Nucl Medicine Physician) -- Dosimetry (Physicist) -- Published guidelines on radioisotope treatment of hepatocellular cancer (Nucl Medicine Physician and Oncologist) -- NEUROENDOCRINE TUMORS -- Radiopharmaceuticals for treatment of neuroendocrine tumors (mechanisn of action, biodistribution, doses) (Radiochemis inPaediatric tumors of neuroendocrine origin (Oncologist) -- Treatment with 131I—MIBG (indications procedures and results) (Nucl Medicine Physician) -- Dosimetry (Physicist) -- GEP neuroendocrine tumors (Oncologist) -- PPRT with 90Y labeled peptides (indications ,procedures and results) (Nucl Medicine Physician) -- Dosimetry (Physicist) -- Published guidelines on radioisotope treatment of Neuroendocrine tumors(Nucl Medicine Physician and Oncologist) -- LYMPHOMAS -- Selection of lymphoma patients candidates for Radioimmunotherapy (Haematologist) -- Radiopharmaceuticals for treatment of neuroendocrine tumors (mechanisn of action, biodistribution, doses) (Radiochemist) -- Treatment with anti-CD20 Antibodies ( 90Y- ibritumomab /131 I- Tositumomab) (indications and procedures and results) (Nucl Medicine Physician) -- Radioimmunotherapy at high doses of lymphomas (Nucl Medicine Physician) -- Published guidelines on radioisotope treatment of Lymphomas (Nucl Medicine Physician and Oncologist) -- PROSTATE CANCER -- Overview on bone metastases from prostate cancer (Urologist, Oncologist) -- Radiopharmaceuticals for treatment of bone metastases (mechanisn of action, biodistribution, doses) (Radiochemist) -- Targeted therapy with 223Ra dichloride of bone metastases(Nucl Medicine Physician) -- Novel approaches of treatment with 223Ra based targeted therapy (Nucl Medicine Physician) -- Dosimetry (Physicist) -- Published guidelines on radioisotope treatment of Bone Metastases (Nucl Medicine Physician and Oncologist).
- Format
- e-Book
- Location
- Online
A History of Radionuclide Studies in the UK : 50th Anniversary of the British Nuclear Medicine Society
https://libcat.nshealth.ca/en/permalink/provcat40096
Ralph McCready, Gopinath Gnanasegaran, Jamshed B. Bomanji, editors.
--Cham:
Springer
, c2016.
- Available Online
- View e-Book
- Access
- Open access
- Location
- Online
The British Nuclear Medicine Society celebrates its 50th Anniversary with this booklet, which reflects the research of many of the pioneers in the use of radionuclides for the diagnosis and therapy of human disease. Since 1949 there have been remarkable advances in radionuclide techniques and imaging equipment: from the first devices "home-made" in the many physics departments throughout the UK, to the sophisticated multimodality imagers now in everyday use in Nuclear Medicine. The BNMS has bee…
- Available Online
- View e-Book
- Other Authors
- McCready, Ralph
- Gnanasegaran, Gopinath
- Bomanji, Jamshed B
- Responsibility
- Ralph McCready, Gopinath Gnanasegaran, Jamshed B. Bomanji, editors
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2016
- Physical Description
- 1 online resource (xviii, 152 p. : 74 illus., 57 illus. in color)
- ISBN
- 9783319286242
- 9783319286235 (print ed.)
- Subjects (MeSH)
- History of Medicine
- Nuclear Medicine - history
- Radioisotopes - history
- Societies, Medical - history
- Other Subjects
- British Nuclear Medicine Society
- Other Subjects
- United Kingdom
- Specialty
- History of Medicine
- Radiology
- Abstract
- The British Nuclear Medicine Society celebrates its 50th Anniversary with this booklet, which reflects the research of many of the pioneers in the use of radionuclides for the diagnosis and therapy of human disease. Since 1949 there have been remarkable advances in radionuclide techniques and imaging equipment: from the first devices "home-made" in the many physics departments throughout the UK, to the sophisticated multimodality imagers now in everyday use in Nuclear Medicine. The BNMS has been instrumental in promoting the use of radionuclide techniques in the investigation of pathology by supporting and providing education, research and guidelines on the optimum use of radiation to help patients. The future of Nuclear Medicine is bright, thanks to improved imaging resolution, new radiopharmaceuticals, and new diagnostic and therapeutic techniques and procedures.
- Contents
- 1. History of the BNMS 1966–2016 -- 2. A History of Nuclear Medicine in the UK -- 3. The Evolution of Training in Nuclear Medicine in the UK -- 4. A Technologists Viewpoint -- 5. Evolution of Nuclear Medicine Physics in the UK -- 6. The Institute of Nuclear Medicine London -- 7. A History of Nuclear Medicine in the UK Radionuclide Investigation of the Brain -- 8. A History of Nuclear Cardiology in the UK -- 9. Great Ormond Street Hospital for Children, Paediatric Nuclear Medicine in the UK -- 10. Renal Radionuclide Studies -- 11. St Bartholomew’s Hospital and Medical School: Department of Nuclear Medicine -- 12. Nuclear Medicine at the Hammersmith Hospital -- 13. Nuclear Medicine in Nottingham: Antibodies, Gamma Probes and Drug Delivery -- 14. The Introduction and Development of Clinical PET in the United Kingdom -- 15. Bone Radionuclide Imaging, Quantitation and Bone Densitometry -- 16. Therapeutic Nuclear Medicine in the UK -- 17. Hospital Radiopharmacy in the UK -- 18. Development of Computers in Nuclear Medicine -- 19. The Future Direction of Radiopharmaceutical Development -- 20. A Personal Reflection.
- Access
- Open access
- Format
- e-Book
- Publication Type
- Festschrift
- Location
- Online
Local Treatment of Inflammatory Joint Diseases : Benefits and Risks
https://libcat.nshealth.ca/en/permalink/provcat39263
Willm Uwe Kampen, Manfred Fischer, editors.
--Cham:
Springer
, c2015.
- Available Online
- View e-Book
- Location
- Online
This book presents a systematic survey of different local treatments in inflammatory joint diseases and their potential side effects and complications. Both surgical therapies and pharmaceutical strategies involving local or systemic application of anti-inflammatory and immunomodulating drugs are addressed. Special emphasis is placed on nuclear medicine therapy by intra-articular instillation of beta radiation emitters, known as radiosynoviorthesis or radiation synovectomy. Possible complicatio…
- Available Online
- View e-Book
- Other Authors
- Kampen, Willm Uwe
- Fischer, Manfred
- Responsibility
- Willm Uwe Kampen, Manfred Fischer, editors
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2015
- Physical Description
- 1 online resource (viii, 144 p. : 26 illus., 23 illus. in color)
- ISBN
- 9783319169491
- 9783319169484 (print ed.)
- Subjects (MeSH)
- Arthritis, Rheumatoid - radiotherapy
- Erbium - therapeutic use
- Radioisotopes - therapeutic use
- Rhenium - therapeutic use
- Synovitis - radiotherapy
- Yttrium Radiosotopes - therapeutic use
- Abstract
- This book presents a systematic survey of different local treatments in inflammatory joint diseases and their potential side effects and complications. Both surgical therapies and pharmaceutical strategies involving local or systemic application of anti-inflammatory and immunomodulating drugs are addressed. Special emphasis is placed on nuclear medicine therapy by intra-articular instillation of beta radiation emitters, known as radiosynoviorthesis or radiation synovectomy. Possible complications, in particular radionecrosis, infection, and thromboembolism, are described and available treatment strategies are examined in detail. In addition, radiation safety considerations are critically reviewed and relevant clinical questions are discussed. While radiosynoviorthesis is an effective and safe treatment if a proper indication is secured and if the application is performed by an experienced nuclear medicine physician, local complications can never be excluded with certainty. This book will support physicians who are engaged in the care and treatment of patients with inflammatory joint disease, approximately 30,000 of whom undergo radiosynoviorthesis in Europe each year.
- Contents
- 1. Safety of Medicines: Detection and Reporting Adverse Reactions -- Part I. Histopathology and Non-radioactive Treatment of Synovitis -- 2. The Role of Synovial Macrophages in Rheumatoid Arthritis and Osteoarthritis: Its Implications for Radiosynovectomy -- 3 Intra-articular Corticosteroid Treatment of Inflammatory Joint Diseases -- 4. NSAIDs -- 5. Synovectomy of Rheumatoid Joints -- Part II. Radiosynoviorthesis – Possible Side Effects and Complications -- 6. Radiosynovectomy: Introduction and Overview of the Literature -- 7. Dosimetry and Radiation Exposure of Patients -- 8. Radiation Exposure of Medical Staff and Radiation Protection Measures -- 9. Local Complications After Radiosynovectomy and Possible Treatment Strategies: A Literature Survey -- 10. Risk of Cancer Induction -- 11. Baker’s Cysts: A Relevant Contraindication? -- Summary.
- Format
- e-Book
- Location
- Online
Nuclear medicine physics : the basics
https://libcat.nshealth.ca/en/permalink/provcat21547
Chandra, Ramesh.
(6th ed.)
--Philadelphia, PA:
Lippincott Williams & Wilkins
, 2004.
- Call Number
- WN 110 C456n 2004
- Location
- Halifax Infirmary
- Call Number
- WN 110 C456n 2004
- Author
- Chandra, Ramesh
- Edition
- 6th ed.
- Place of Publication
- Philadelphia, PA
- Publisher
- Lippincott Williams & Wilkins
- Date of Publication
- 2004
- Physical Description
- 201 p.
- ISBN
- 0781747538
- Subjects (MeSH)
- Nuclear Medicine
- Health Physics
- Radioisotopes
- Technology, Radiologic
- Format
- Book
- Location
- Halifax Infirmary
- Loan Period
- 3 weeks
Nuclear medicine therapy : principles and clinical applications
https://libcat.nshealth.ca/en/permalink/provcat32378
Cumali Aktolun, Stanley J. Goldsmith, editors.
--New York, NY:
Springer
, c2013.
- Available Online
- View e-Book
- Location
- Online
Nuclear Medicine Therapy presents the state of the art in targeted radionuclide therapy, both in clinical practice and contemporary clinical investigation and trials. With contributions from an internationally-distinguished group of physicians and scientists, the book is devoted entirely to the use of nuclear medicine techniques and technology for therapy of malignant and benign diseases. Individual chapters cover the scientific principles and clinical applications of radionuclide therapy and t…
- Available Online
- View e-Book
- Other Authors
- Aktolun, Cumali
- Goldsmith, Stanley J
- Responsibility
- Cumali Aktolun, Stanley J. Goldsmith, editors
- Place of Publication
- New York, NY
- Publisher
- Springer
- Date of Publication
- c2013
- Physical Description
- 1 online resource (xx, 443 p. : 120 ill., 62 ill. in color)
- ISBN
- 9781461440215
- Subjects (MeSH)
- Nuclear Medicine - methods
- Radioimmunotherapy - methods
- Radioisotopes - therapeutic use
- Radiopharmaceuticals - therapeutic use
- Subjects (LCSH)
- Radiology, Medical
- Nuclear medicine
- Radiotherapy
- Abstract
- Nuclear Medicine Therapy presents the state of the art in targeted radionuclide therapy, both in clinical practice and contemporary clinical investigation and trials. With contributions from an internationally-distinguished group of physicians and scientists, the book is devoted entirely to the use of nuclear medicine techniques and technology for therapy of malignant and benign diseases. Individual chapters cover the scientific principles and clinical applications of radionuclide therapy and the state of clinical trials of agents currently under investigation in the therapy of tumors involving virtually every organ system. Due to overlapping interest in techniques, indications, and clinical use, the development of radionuclide therapy attracts considerable input from other medical specialists whose collaboration is essential, including radiation and medical oncologists, hematologists, diagnostic radiologists, hepatologists, endocrinologists, and rheumatologists. And because radionuclide therapy is a rapidly evolving field of nuclear medicine, it is the aim of this volume to appeal to all specialists involved in targeted radionuclide therapy and to contribute to the standardization of the practice globally.
- Contents
- Lymphoma -- Leukemia -- Myeloproliferative Neoplasms -- Neuroendocrine Tumors -- Bone Metastases and Bone Pain -- Melanoma -- Brain Tumors -- Well Differentiated ThyroidCarcinomas -- Medullary Carcinoma of Thyroid -- Breast Carcinoma -- Liver Tumors-Radiomicrosphere Therapy -- Liver Tumors-Systemic Radionuclide Therapy -- Colo-rectal Carcinoma -- Pancreatic Carcinoma -- Renal Cell Carcinoma -- Prostate Carcinoma -- Radioiodine Therapy of Benign Thyroid Diseases -- Radiosynoviorthesis -- Chemistry of Therapeutic Radiopharmaceuticals -- Pretargeting: Advancing the Delivery of Therapeutic Radionuclides -- Radiobiology and Low Dose Rate Radiation Effects -- Radiation Safety Considerations for Radionuclide Therapy -- Challenges Associated with Radionuclide Therapy.
- Format
- e-Book
- Location
- Online
Radionuclide and Hybrid Bone Imaging
https://libcat.nshealth.ca/en/permalink/provcat31084
Ignac Fogelman, Gopinath Gnanasegaran, Hans Wall, editors.
--Berlin, Heidelberg:
Springer
, c2012.
- Available Online
- View e-Book
- Location
- Online
The accurate identification of pathology in the skeleton is an extremely important goal, and the great strength of the radionuclide bone scan is its ability to identify functional change before structural change occurs. Over the years, the indications for bone scan have evolved to include benign disorders as well as malignancies. Further striking developments include the emergence of PET and of new tracers that offer enhanced capabilities, such as 18F-fluoride. The most dramatic advance, howeve…
- Available Online
- View e-Book
- Other Authors
- Fogelman, Ignac
- Gnanasegaran, Gopinath
- Wall, Hans
- Responsibility
- Ignac Fogelman, Gopinath Gnanasegaran, Hans Wall, editors
- Place of Publication
- Berlin, Heidelberg
- Publisher
- Springer
- Date of Publication
- c2012
- Physical Description
- 1 online resource (xiv, 1046 p. : 641 ill., 294 ill. in color)
- ISBN
- 9783642024009
- Subjects (MeSH)
- Bone Diseases - diagnostic imaging
- Bone and Bones - diagnostic imaging
- Positron-Emission Tomography - methods
- Positron-Emission Tomography Computed Tomography - methods
- Subjects (LCSH)
- Nuclear medicine
- Oncology
- Orthopedics
- Abstract
- The accurate identification of pathology in the skeleton is an extremely important goal, and the great strength of the radionuclide bone scan is its ability to identify functional change before structural change occurs. Over the years, the indications for bone scan have evolved to include benign disorders as well as malignancies. Further striking developments include the emergence of PET and of new tracers that offer enhanced capabilities, such as 18F-fluoride. The most dramatic advance, however, has been the development of hybrid imaging systems that combine the strengths of different modalities. This book, written by authors with national and international reputations in the field, covers all aspects of radionuclide and hybrid bone imaging. Introductory sections present the basic science and consider the current status and limitations of conventional radiological techniques. The underlying principles of PET-CT and SPECT-CT are carefully explained, and the value of different PET and SPECT tracers, assessed. The role of single- and dual-modality approaches in the imaging of benign bone diseases and malignancies is then discussed in detail in a series of well-illustrated chapters. The pathologies addressed include metabolic bone disease, arthritis, bone and joint infections, primary bone and soft tissue tumors, and metastases from breast and prostate cancer. A further section considers the role of bone scintigraphy in the pediatric patient, and the closing chapters focus on miscellaneous subjects, including bone densitometry and radionuclide targeted therapy.
- Contents
- BONE AND BASICS SCIENCES -- Anatomy of the Skeletal System -- Physiology of Bone Formation, Remodeling, and Metabolism -- Pathophysiology of Bone Metastases -- Skeletal Tracer Kinetics: Science and Practice -- Biochemical Markers in Bone Diseases -- BONE AND CONVENTIONAL RADIOLOGY -- Basics of CT -- Basic Principles of MRI -- Radiological Imaging in Metastatic Bone Disease and Myeloma: Current Status and Limitations -- Radiological Imaging of Primary Benign and Malignant Bone Tumours -- Radiological Imaging in Trauma and Sports Injuries: Current Status and Limitations -- Radiological Imaging in Arthritis: Current Status and Limitations -- RADIONUCLIDE BONE IMAGING: SCIENCE AND PRACTICE -- Basic Principles of SPECT and PET Imaging -- Technical Challenges and Pitfalls in Hybrid Imaging -- Bone Scintigraphy: SPECT and PET Tracers -- Bone Scintigraphy: Patterns, Variants, Limitations and Artefacts -- Soft Tissue Uptake in Radionuclide Bone Scintigraphy -- BONE SCINTIGRAPHY IN BENIGN BONE DISEASE -- Bone Scintigraphy in Metabolic Bone Disease -- Bone Scintigraphy in Arthritis -- Bone Scintigraphy in Trauma and Sport Injuries -- SPECT and PET in the Assessment of Bone Infections -- BONE SCINTIGRAPHY IN BENIGN BONE DISEASE -- Nuclear Medicine in the Assessment of Painful Joint Prostheses -- Radionuclide Bone Imaging in Skeletal Tuberculosis -- Hybrid Imaging in the Management of Complex Foot and Ankle Problems -- Wrist Registration: Conventional Radionuclide and SPECT/CT Imaging -- BONE SCINTIGRAPHY IN BONE METASTASES -- Prostate Cancer: Role of Conventional Radionuclide and Hybrid Bone Imaging -- Breast Cancer: Role of Planar, SPECT and PET in Imaging Bone Metastases -- Lung, Thyroid, Renal Cancer, Myeloma and Neuroendocrine Cancers: Role of Planar, SPECT and PET in Imaging Bone Metastases -- Conventional Nuclear Medicine and Hybrid Imaging in Monitoring the Treatment of Skeletal Malignancy -- Potential Applications and Limitations of SPECT-CT in Classifying Bone Lesions in Patients with Cancer -- Primary Bone and Soft Tissue Tumours: Role of SPECT -- Primary Bone and Soft Tissue Tumours: Role of 18FDG PET -- Radioisotopes in the Treatment of Bone Metastases -- Radionuclide Bone Marrow Imaging in Cancer Patients -- PAEDIATRIC BONE SCINTIGRAPHY -- Pediatric Bone Scintigraphy: Variants and Limitations -- Paediatric Bone Scintigraphy: Benign Bone Disease -- Paediatric Bone Scintigraphy: Bone Metastases -- Hybrid Bone Imaging in Pediatrics -- BONE AND MISCELLANEOUS SCENARIOS -- Bone Densitometry: Science and Practice -- Radiosynovectomy: Science and Practice -- Radiosynoviorthesis (Radiation Synovectomy) of Knee Joint -- Common Orthopaedic Presentations -- Radiological Imaging in Infection: Current Status and Limitations.
- Format
- e-Book
- Location
- Online
Radiopharmaceutical Chemistry
https://libcat.nshealth.ca/en/permalink/provcat44334
Jason S. Lewis, Albert D. Windhorst, Brian M. Zeglis, editors.
--Cham:
Springer
, 2019.
- Available Online
- View e-Book
- Location
- Online
This book is a comprehensive guide to radiopharmaceutical chemistry. The stunning clinical successes of nuclear imaging and targeted radiotherapy have resulted in rapid growth in the field of radiopharmaceutical chemistry, an essential component of nuclear medicine and radiology. However, at this point, interest in the field outpaces the academic and educational infrastructure needed to train radiopharmaceutical chemists. For example, the vast majority of texts that address radiopharmaceutical …
- Available Online
- View e-Book
- Other Authors
- Lewis, Jason S.
- Windhorst, Albert D.
- Zeglis, Brian M.
- Responsibility
- Jason S. Lewis, Albert D. Windhorst, Brian M. Zeglis, editors
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- 2019
- Physical Description
- 1 online resource (xviii, 651 p.) : 530 illus., 318 illus. in color
- ISBN
- 9783319989471
- 9783319989464 (Print ed.)
- 9783319989488 (Print ed.)
- Subjects (MeSH)
- Nuclear Pharmacy
- Radiochemistry
- Radiopharmaceuticals - chemistry
- Specialty
- Pharmacy
- Radiotherapy
- Abstract
- This book is a comprehensive guide to radiopharmaceutical chemistry. The stunning clinical successes of nuclear imaging and targeted radiotherapy have resulted in rapid growth in the field of radiopharmaceutical chemistry, an essential component of nuclear medicine and radiology. However, at this point, interest in the field outpaces the academic and educational infrastructure needed to train radiopharmaceutical chemists. For example, the vast majority of texts that address radiopharmaceutical chemistry do so only peripherally, focusing instead on nuclear chemistry (i.e. nuclear reactions in reactors), heavy element radiochemistry (i.e. the decomposition of radioactive waste), or solely on the clinical applications of radiopharmaceuticals (e.g. the use of PET tracers in oncology). This text fills that gap by focusing on the chemistry of radiopharmaceuticals, with key coverage of how that knowledge translates to the development of diagnostic and therapeutic radiopharmaceuticals for the clinic. The text is divided into three overarching sections: First Principles, Radiochemistry, and Special Topics. The first is a general overview covering fundamental and broad issues like “The Production of Radionuclides” and “Basics of Radiochemistry”. The second section is the main focus of the book. In this section, each chapter’s author will delve much deeper into the subject matter, covering both well established and state-of-the-art techniques in radiopharmaceutical chemistry. This section will be divided according to radionuclide and will include chapters on radiolabeling methods using all of the common nuclides employed in radiopharmaceuticals, including four chapters on the ubiquitously used fluorine-18 and a “Best of the Rest” chapter to cover emerging radionuclides. Finally, the third section of the book is dedicated to special topics with important information for radiochemists, including “Bioconjugation Methods,” “Click Chemistry in Radiochemistry”, and “Radiochemical Instrumentation.” This is an ideal educational guide for nuclear medicine physicians, radiologists, and radiopharmaceutical chemists, as well as residents and trainees in all of these areas.
- Contents
- Part I. First Principles -- Why Nuclear Imaging and Radiotherapy? -- A Short History of Nuclear Medicine -- The Basics of Nuclear Chemistry and Radiochemistry: An Introduction to Nuclear Transformations and Radioactive Emissions -- Methods for the Production of Radionuclides for Medicine -- An Overview of Targeted Radiotherapy -- An Overview of Nuclear Imaging -- Small Molecules as Radiopharmaceutical Vectors -- Peptides as Radiopharmaceutical Vectors -- Immunoglobulins as Radiopharmaceutical Vectors -- Nanoparticles as Radiopharmaceutical Vectors -- Part II. Radiochemistry -- The Radiopharmaceutical Chemistry of Carbon-11: Basic Principles -- The Radiopharmaceutical Chemistry of Carbon-11: Tracers and Applications -- The Radiopharmaceutical Chemistry of Nitrogen-13 and Oxygen-15 -- The Radiopharmaceutical Chemistry of the Radionuclides of Gallium and Indium -- The Radiopharmaceutical Chemistry of Fluorine-18: Nucleophilic Fluorinations -- The Radiopharmaceutical Chemistry of Fluorine-18: Electrophilic Fluorinations -- The Radiopharmaceutical Chemistry of Fluorine-18: Next-Generation Fluorinations -- The Radiopharmaceutical Chemistry of Technetium-99m -- The Radiopharmaceutical Chemistry of the Radioisotopes of Copper -- The Radiopharmaceutical Chemistry of the Radioisotopes of Lutetium and Yttrium -- The Radiopharmaceutical Chemistry of Zirconium-89 -- The Radiopharmaceutical Chemistry of the Radioisotopes of Iodine -- The Radiopharmaceutical Chemistry of Alpha-Emitting Radionuclides -- The Radiopharmaceutical Chemistry of Seldom-Used Radionuclides in Nuclear Medicine -- Part III. Special Topics -- Bioconjugation Methods for Radiopharmaceutical Chemistry -- Click Chemistry in Radiopharmaceutical Chemistry -- Equipment and Instrumentation for Radiopharmaceutical Chemistry -- Kinetic Modeling of Radiotracers -- An Introduction to Radiation Protection -- An Introduction to Biostatistics -- Choosing a Target for Nuclear Imaging or Targeted Radiotherapy -- Target Identification, Lead Discovery, and Optimization -- Preclinical Experimentation in Oncology -- Preclinical Experimentation in Neurology -- The Clinical Translation Process in Europe -- The Clinical Translation Process in the United States -- Setting Up a Successful Radiopharmaceutical Production Facility.
- Format
- e-Book
- Location
- Online
Radiopharmaceuticals for Therapy
https://libcat.nshealth.ca/en/permalink/provcat40426
F. F. (Russ) Knapp, Ashutosh Dash.
(1st ed.)
--New Delhi:
Springer India
, c2016.
- Available Online
- View e-Book
- Location
- Online
This book provides detailed information on therapeutic radiopharmaceuticals and discusses emerging technologies which have potential for broad clinical implementation. Recent advances in molecular biology, radiopharmaceutical chemistry and radioisotope production have stimulated a new era for the use of radiopharmaceuticals for targeted radionuclide therapy (TRT). Emerging clinical trials include use of peptides and monoclonal antibodies radiolabeled with therapeutic radionuclides for cancer th…
- Available Online
- View e-Book
- Author
- Knapp, F. F. (Russ)
- Other Authors
- Dash, Ashutosh
- Responsibility
- F. F. (Russ) Knapp, Ashutosh Dash
- Edition
- 1st ed.
- Place of Publication
- New Delhi
- Publisher
- Springer India
- Date of Publication
- c2016
- Physical Description
- 1 online resource (xxiv, 347 p. : 157 illus., 72 illus. in color)
- ISBN
- 9788132226079
- 9788132226062 (print ed.)
- Abstract
- This book provides detailed information on therapeutic radiopharmaceuticals and discusses emerging technologies which have potential for broad clinical implementation. Recent advances in molecular biology, radiopharmaceutical chemistry and radioisotope production have stimulated a new era for the use of radiopharmaceuticals for targeted radionuclide therapy (TRT). Emerging clinical trials include use of peptides and monoclonal antibodies radiolabeled with therapeutic radionuclides for cancer therapy. In addition, small molecules are used for the treatment of chronic diseases such as metastatic bone pain palliation and radiation synovectomy of inflammatory joints. In the interventional arena, therapy of primary and metastatic liver cancer and arterial restenosis following angioplasty of both the coronary and peripheral arteries are being explored. Reactor and accelerator production of therapeutic radioisotopes is also integrated into these discussions. The development and use of radiopharmaceutical targeting characteristics required for treatment of specific disease processes and how these are implemented for radiopharmaceutical design strategies are also described. Radiopharmaceuticals for Therapy will benefit audiences in nuclear medicine and radionuclide therapy and will thus prove an invaluable source of up-to-date information for students, radiopharmaceutical scientists and professionals working in the radiopharmacy and nuclear medicine specialties.
- Contents
- Part I. Radiopharmaceuticals -- 1. Introduction: Radiopharmaceuticals Play an Important Role in Both Diagnostic and Therapeutic Nuclear Medicine -- 2. Therapeutic Radionuclides Decay with Particle Emission for Therapeutic Applications -- 3. Alpha Radionuclide Therapy -- 4. Auger Electron-Based Radionuclide Therapy -- Part II. Production, Processing and Availability of Therapeutic Radioisotopes -- 5. Reactor-Produced Therapeutic Radionuclides -- 6. Accelerator-Produced Therapeutic Radionuclides -- 7. Radionuclide Generator Systems Represent Convenient Production Systems to Provide Therapeutic Radionuclides -- 8. Availability of Alpha-Emitting Radioisotopes by Reactor and Accelerator Production and via Decay of Naturally Occurring Parents -- Part III. Therapeutic Radiopharmaceuticals for Cancer Therapy -- 9. Radioimmunotherapy (RIT) -- 10. Peptide Receptor Radionuclide Therapy (PRRT) -- 11. Therapeutic Radiopharmaceuticals for Treatment of Primary and Metastatic Hepatic Cancer -- Part IV. Therapeutic Radiopharmaceuticals for Treatment of Chronic Disease -- 12. Therapeutic Radiopharmaceuticals for Bone Pain Palliation -- 13. Locoregional Radionuclide Therapy for Nonmelanoma Skin Cancer (NMSC) -- 14. Radionuclide Synovectomy: Treatment of Inflammation of the Synovial Joints -- 15. Inhibition of Arterial Restenosis Following Balloon Angioplasty -- Part V. Looking Ahead: New Radiopharmaceutical Strategies for Therapeutic Applications -- 16. Moving Forward: Expected Opportunities for the Development of New Therapeutic Agents Based on Nanotechnologies -- 17. Translation of Radiopharmaceuticals from Bench to Bedside: Regulatory and Manufacturing Issues -- Glossary: Definitions and Terminology.
- Format
- e-Book
- Location
- Online
Scintigraphie osseuse
https://libcat.nshealth.ca/en/permalink/chpams36521
Nova Scotia Health Authority. QEII. Diagnostic Imaging.
Halifax, NS:
Nova Scotia Health Authority
, 2018.
- Pamphlet Number
- 1956
- Available Online
- View Pamphlet
La scintigraphie osseuse est effectuée au Service de médecine nucléaire. Une quantité très petite et sécuritaire de matière radioactive (radio-isotope) est injectée. La dose est tellement faible qu’elle ne vous fera aucun mal. Une caméra gamma est utilisée pour prendre des images. La présente ressource indique comment se préparer (quoi porter et apporter), ainsi que les étapes de l’examen. Si vous n’êtes pas en mesure de vous rendre à votre rendez-vous, veuillez appeler le plus tôt possible afi…
- Available Online
- View Pamphlet
- Corporate Author
- Nova Scotia Health Authority. QEII. Diagnostic Imaging
- Alternate Title
- Bone scan
- Place of Publication
- Halifax, NS
- Publisher
- Nova Scotia Health Authority
- Date of Publication
- 2018
- Format
- Pamphlet
- Language
- French
- Physical Description
- 1 electronic document ([4] p.) : digital, PDF file
- Subjects (LCSH)
- Diagnostic imaging
- Radioisotope scanning
- Abstract
- La scintigraphie osseuse est effectuée au Service de médecine nucléaire. Une quantité très petite et sécuritaire de matière radioactive (radio-isotope) est injectée. La dose est tellement faible qu’elle ne vous fera aucun mal. Une caméra gamma est utilisée pour prendre des images. La présente ressource indique comment se préparer (quoi porter et apporter), ainsi que les étapes de l’examen. Si vous n’êtes pas en mesure de vous rendre à votre rendez-vous, veuillez appeler le plus tôt possible afin que nous puissions donner cette place à un autre patient.
- This is a French translation of the English pamphlet 0425, “Bone Scan”. A bone scan is done in the Nuclear Medicine Department. A very small, safe amount of radioactive material (radioisotope) is given. The dosage of the radioactive material is so small that it will not harm you. A gamma camera is used to take pictures. Getting ready for the test (what to wear and bring) is outlined. The steps of the test are provided. If you are unable to keep your appointment, please call immediately so that another patient can be booked.
- Responsibility
- Prepared by: Diagnostic Imaging
- Pamphlet Number
- 1956
Targeted Radionuclide Tumor Therapy : Biological Aspects
https://libcat.nshealth.ca/en/permalink/provcat28885
edited by Torgny Stigbrand, Jörgen Carlsson, Gregory P. Adams.
--[Dordrecht]:
Springer Science+Business Media
, c2008.
- Available Online
- View e-Book
- Location
- Online
- Available Online
- View e-Book
- Author
- Stigbrand, Torgny
- Other Authors
- Carlsson, Jörgen
- Adams, Gregory P
- Responsibility
- edited by Torgny Stigbrand, Jörgen Carlsson, Gregory P. Adams
- Place of Publication
- [Dordrecht]
- Publisher
- Springer Science+Business Media
- Date of Publication
- c2008
- ISBN
- 9781402086960
- Subjects (MeSH)
- Antibodies - therapeutic use
- Radioisotopes - therapeutic use
- Subjects (LCSH)
- Oncology
- Radiology, Medical
- Nuclear medicine
- Format
- e-Book
- Location
- Online
Theranostics, Gallium-68, and Other Radionuclides : A Pathway to Personalized Diagnosis and Treatment
https://libcat.nshealth.ca/en/permalink/provcat32494
Richard P. Baum, Frank Rösch, editors.
--Berlin, Heidelberg:
Springer
, c2013.
- Available Online
- View e-Book
- Location
- Online
This book is based on contributions presented at the 1st World Congress on Gallium-68 and Peptide Receptor Radionuclide Therapy, which examined recent developments in theranostics: the emerging field of molecular targeting of vectors that can be used for both diagnosis and therapy, when modified accordingly. The focus of this book is on the rapidly developing research into and clinical applications of gallium-68 and other generator-produced PET radionuclides in the personalized diagnosis and tr…
- Available Online
- View e-Book
- Other Authors
- Baum, Richard P
- Rösch, Frank
- Responsibility
- Richard P. Baum, Frank Rösch, editors
- Place of Publication
- Berlin, Heidelberg
- Publisher
- Springer
- Date of Publication
- c2013
- Physical Description
- 1 online resource (xviii, 576 p. : 180 ill., 122 ill. in color)
- Series Vol.
- 194
- Series Title
- Recent results in cancer research
- ISBN
- 9783642279942
- Subjects (MeSH)
- Gallium Radioisotopes - diagnostic use
- Neoplasms - diagnosis
- Neoplasms - therapy
- Positron-Emission Tomography Computed Tomography
- Radionuclide Imaging
- Radiopharmaceuticals
- Subjects (LCSH)
- Radiology, Medical
- Nuclear medicine
- Radiotherapy
- Oncology
- Abstract
- This book is based on contributions presented at the 1st World Congress on Gallium-68 and Peptide Receptor Radionuclide Therapy, which examined recent developments in theranostics: the emerging field of molecular targeting of vectors that can be used for both diagnosis and therapy, when modified accordingly. The focus of this book is on the rapidly developing research into and clinical applications of gallium-68 and other generator-produced PET radionuclides in the personalized diagnosis and treatment of neuroendocrine tumors and other diseases. In addition, new PET radiopharmaceuticals are considered, and the latest ideas and concepts, presented. Theranostics embodies both molecular and personalized medicine. It is at the cutting edge of medicine, and the contents of this volume will be of interest to chemists, physicians, and investigators dealing with generators, PET radiochemistry,ámolecular imaging, and radionuclide therapy.
- Format
- e-Book
- Location
- Online
