schmitt found 12 records - Provincial Hospitals Library Catalogue

The International Academy of Cytology Yokohama System for Reporting Breast Fine Needle Aspiration Biopsy Cytopathology

https://libcat.nshealth.ca/en/permalink/provcat45315

Andrew S. Field, Wendy A. Raymond, Fernando Schmitt, editors. --Cham: Springer , c2020.

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Location: Online

This text describes a system of reporting breast fine needle aspiration biopsy that uses five clearly defined categories, each described by a specific term and each with a specific risk of malignancy. The five categories are insufficient/inadequate, benign, atypical, suspicious of malignancy and malignant. Each category has a risk of malignancy and is linked to management recommendations, which include several options because it is recognized that diagnostic infrastructure, such as the availabi…

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Other Authors: Field, Andrew S.; Raymond, Wendy A.; Schmitt, Fernando

Other Authors: International Academy of Cytology

Responsibility: Andrew S. Field, Wendy A. Raymond, Fernando Schmitt, editors

Place of Publication: Cham

Publisher: Springer

Date of Publication: c2020

Physical Description: 1 online resource (xii, 185 p.) : 119 illus. in color

ISBN: 9783030268831; 9783030268824 (Print ed.); 9783030268848 (Print ed.); 9783030268855 (Print ed.)

Subjects (MeSH): Biopsy, Fine-Needle; Breast Neoplasms - pathology; Cytodiagnosis

Specialty: Cell Biology; Pathology

Abstract: This text describes a system of reporting breast fine needle aspiration biopsy that uses five clearly defined categories, each described by a specific term and each with a specific risk of malignancy. The five categories are insufficient/inadequate, benign, atypical, suspicious of malignancy and malignant. Each category has a risk of malignancy and is linked to management recommendations, which include several options because it is recognized that diagnostic infrastructure, such as the availability of core needle biopsy and ultrasound guidance, vary between developed and low and middle income countries. This text includes key diagnostic cytological criteria for each of the many lesions and tumors found in the breast. The cytopathology of specific lesions is illustrated with high quality photomicrographs with clear figure descriptions. Chapters also discuss current and potential future ancillary tests, liquid based cytology, nipple cytology and management. An additional chapter provides an overview of an approach to the diagnosis of direct smears of breast fine needle aspiration biopsies. The International Academy of Cytology Yokohama System for Reporting Breast Fine Needle Aspiration Biopsy Cytopathology provides a clear logical approach to the diagnosis and categorization of breast lesions by FNAB cytology, and aims to facilitate communication with breast clinicians, further research into breast cytopathology and related molecular pathology, and improve patient care.

Contents: The International Academy of Cytology Yokohama System for Reporting Breast Fine Needle Aspiration Biopsy Cytopathology: Introduction and Overview -- Insufficient/Inadequate -- Benign -- Atypical -- Suspicious of Malignancy -- Malignant -- An Approach to the Interpretation of Breast Fine Needle Aspiration Biopsy Cytology Direct Smears -- Nipple Cytology -- Role of Ancillary Tests in Breast Fine Needle Aspiration Biopsy Cytology -- Fine Needle Aspiration Biopsy Cytology of the Breast Utilizing Liquid-based Preparations -- Clinical Management.

Format: e-Book

Location: Online

Bone Marrow Biopsy Pathology : A Practical Guide

https://libcat.nshealth.ca/en/permalink/provcat45319

Christine Beham-Schmid, Annette Schmitt-Graeff. --Berlin, Heidelberg: Springer , c2020.

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Location: Online

This comprehensive, superbly illustrated reference is designed to provide practical diagnostic assistance for hematopathologists when dealing with common and uncommon lesions in bone marrow trephine biopsies (BMTBs). At the heart of the book is a systematic analysis of neoplastic hematological and non-hematological disease entities, with concise identification of the key features of myeloproliferative neoplasms, myelodysplastic syndromes, acute and chronic leukemias, eosinophilia-associated mye…

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Author: Beham-Schmid, Christine

Other Authors: Schmitt-Graeff, Annette

Responsibility: Christine Beham-Schmid, Annette Schmitt-Graeff

Place of Publication: Berlin, Heidelberg

Publisher: Springer

Date of Publication: c2020

Physical Description: 1 online resource (xix, 533 p.) : 403 illus. in color

Series Title: Essentials of diagnostic pathology

ISBN: 9783662603093; 9783662603079 (Print ed.); 9783662603086 (Print ed.)

ISSN: 2194-6256

Subjects (MeSH): Biopsy; Bone Marrow - pathology; Bone Marrow Diseases - diagnosis; Bone Marrow Neoplasms - diagnosis

Specialty: Hematology; Medical Oncology; Pathology

Abstract: This comprehensive, superbly illustrated reference is designed to provide practical diagnostic assistance for hematopathologists when dealing with common and uncommon lesions in bone marrow trephine biopsies (BMTBs). At the heart of the book is a systematic analysis of neoplastic hematological and non-hematological disease entities, with concise identification of the key features of myeloproliferative neoplasms, myelodysplastic syndromes, acute and chronic leukemias, eosinophilia-associated myeloid/lymphoid neoplasms, lymphoproliferative disorders, and selected non-hematopoietic malignancies. Relevant examples of BMTBs are presented, with microscopic description, high-quality photomicrographs, and clinical data. The book also explains how to assess hematopoietic and stromal components of normal BMTBs, identifies the heterogeneous patterns that may be observed in healthy individuals, and analyzes reactive conditions, with particular attention to diagnostic problems and pitfalls.

Contents: 1. Normal Bone Marrow -- 2. Non-neoplastic Conditions with Quantitative and Qualitative Changes in Hematopoiesis -- 3. Bone Changes Found in Bone Marrow Biopsies -- 4. Non-hematological Malignancies in the Bone Marrow -- 5. Increase of Plasma Cells, Reactive and Neoplastic -- 6. Inflammatory and Infectious Diseases -- 7. Malignant Lymphomas -- 8. Mastocytosis -- 9. Myeloproliferative Neoplasm (MPN) -- 10. Myeloid/Lymphoid Neoplasms with Eosinophilia and Rearrangement of PDGFRA, PDGFRB, FGFR1, or with PCM1-JAK2 -- 11. Myelodysplastic/Myeloproliferative Neoplasms (MDS/MPN) -- 12. Myelodysplastic Syndromes (MDS) -- 13. Acute Leukemia of Myeloid, Lymphoid, and Ambiguous Lineage and Related Malignancies.

Format: e-Book

Location: Online

The International System for Serous Fluid Cytopathology

https://libcat.nshealth.ca/en/permalink/provcat46008

Ashish Chandra, Barbara Crothers, Daniel Kurtycz, Fernando Schmitt, editors. --Cham: Springer , c2020.

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Location: Online

This book is the culmination of an international effort to bring consistency and diagnostic efficiency to effusion cytology for the sake of patient care. The authors recognize special challenges in serous fluid cytopathology, such as reporting the presence of Mullerian epithelium in peritoneal fluids. What is an appropriate serous fluid volume to ensure adequacy? How should mesothelial proliferations be reported and is it appropriate to make an interpretation of malignant mesothelioma? How spec…

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Other Authors: Chandra, Ashish; Crothers, Barbara; Kurtycz, Daniel; Schmitt, Fernando

Responsibility: Ashish Chandra, Barbara Crothers, Daniel Kurtycz, Fernando Schmitt, editors

Place of Publication: Cham

Publisher: Springer

Date of Publication: c2020

Physical Description: 1 online resource (xxv, 301 p.)

ISBN: 9783030539085; 9783030539078 (Print ed.); 9783030539092 (Print ed.)

Subjects (MeSH): Cytodiagnosis - methods; Serologic Tests - standards

Specialty: Pathology; Serology

Abstract: This book is the culmination of an international effort to bring consistency and diagnostic efficiency to effusion cytology for the sake of patient care. The authors recognize special challenges in serous fluid cytopathology, such as reporting the presence of Mullerian epithelium in peritoneal fluids. What is an appropriate serous fluid volume to ensure adequacy? How should mesothelial proliferations be reported and is it appropriate to make an interpretation of malignant mesothelioma? How specific should a report be regarding the origin and subtyping of tumors found in serous fluids? What are the appropriate quality monitors for this specimen type? Special chapters on considerations for peritoneal washings, cytopreparatory techniques, mesothelioma and quality management are included to address these issues. The text contains literature reviews that elucidate existing evidence in support of current practices and recommendations. Expert opinions on where evidence was lacking, the most common practices were adopted by consensus, and where there was no commonality, are employed. Written by experts in the field, The International System for Serous Fluid Cytopathology serves as a collaborative effort between the International Academy of Cytology and the American Society for Cytopathology and calls upon participation of the international cytopathology and oncology communities to contribute to the development of a truly international system for reporting serous fluid cytology.

Contents: The International System for Reporting Serous Fluid Cytopathology: Introduction and Overview of Diagnostic Terminology and Reporting -- Non-diagnostic (NDX) and Adequacy -- Negative for Malignancy (NFM) -- Atypia of Undetermined Significance -- Suspicious for Malignancy (SFM) -- Malignant-Primary (MAL-P) (Mesothelioma) -- Malignant-Secondary (MAL-S) -- Ancillary Studies for Serous Fluids -- Special Considerations for Peritoneal Washings -- Cytopreparatory Techniques -- Quality Management -- Serous Effusion Anatomy, Biology and Pathophysiology.

Format: e-Book

Location: Online

Molecular Applications in Cytology

https://libcat.nshealth.ca/en/permalink/provcat42591

Fernando C. Schmitt, editor. --Cham: Springer , c2018.

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Location: Online

This book is intended for practicing pathologists and cytopathologists, as well as for pathology trainees and cytotechnicians. It starts with a detailed description of the extremely important pre-analytical phase for molecular testing followed by a presentation of the key tests and their application in different organs, e.g. the lung or thyroid. Step-by-step instructions for the different assays, reporting and clinical integration of the test results are discussed. The authors help the reader t…

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Other Authors: Schmitt, Fernando C.

Responsibility: Fernando C. Schmitt, editor

Place of Publication: Cham

Publisher: Springer

Date of Publication: c2018

Physical Description: 1 online resource (viii, 268 p.) : 61 illus., 60 illus. in color

ISBN: 9783319749426; 9783319749402 (print ed.); 9783319749419 (print ed.)

Subjects (MeSH): Cytological Techniques; Molecular Medicine

Specialty: Cell Biology; Molecular Medicine

Abstract: This book is intended for practicing pathologists and cytopathologists, as well as for pathology trainees and cytotechnicians. It starts with a detailed description of the extremely important pre-analytical phase for molecular testing followed by a presentation of the key tests and their application in different organs, e.g. the lung or thyroid. Step-by-step instructions for the different assays, reporting and clinical integration of the test results are discussed. The authors help the reader to benefit from their experiences by providing a valuable tool for the implementation of these techniques in daily practice. Though the use of molecular techniques is well established in surgical biopsies, to date they are not widely used in connection with cytological material. However, in some fields like lung cancer or aspirates from the pancreas and biliary tract the only available material for diagnosis is the cytological preparation a fact that has created a need for the standardization of molecular techniques on cytology.

Contents: Why Cytology for Molecular Testing? Pros and Cons -- How to Prepare Cytological Samples for Molecular Testing -- Molecular Tests Use in Cytological Material (Analytical Phase) -- Molecular Cytology Applications on Head and Neck -- Molecular Cytology Applications on Lung -- Molecular Cytology of Serous Effusions -- Molecular Cytology Applications on Urine -- Molecular Cytology Applications on Gynecological Cytology -- Molecular Applications in Hematolymphoid Cytology -- Molecular Cytology Application on Thyroid -- Molecular Cytology Applications on Pancreas and Biliary Tract -- Molecular Cytology Applications in Soft Tissue (Pediatric tumors) -- Molecular Cytology Applications in Metastases -- Clinical Integration of Molecular Results on Cytology (Post-analytical Phase).

Format: e-Book

Location: Online

Cytopathology

https://libcat.nshealth.ca/en/permalink/provcat41322

Fernando Schmitt, editor. --Cham: Springer , c2017.

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Location: Online

Available Online: View e-Book

Other Authors: Schmitt, Fernando

Responsibility: Fernando Schmitt, editor

Place of Publication: Cham

Publisher: Springer

Date of Publication: c2017

Physical Description: 1 online resource (xx, 547 pages) : 649 illus. in color

Series Title: Springer reference; Encyclopedia of pathology

ISBN: 9783319332864; 9783319332857 (print ed.)

ISSN: 2366-6269

Subjects (MeSH): Cytodiagnosis; Cytological Techniques

Notes: "eReference"--Publisher.

Contents: Acinic cell carcinoma, cytological findings -- Acute thyroiditis, cytological findings -- Adenoid cystic carcinoma, cytological findings -- Adnexal tumours of the orbit and ocular adnexa -- Adrenal myelolipoma, cytological findings -- Adrenocortical tumors, cytological findings -- Anaplastic carcinoma of thyroid, cytological findings -- Angiomyolipoma, cytological findings -- Apocrine carcinoma, cytological findings -- ASC-H -- ASC-US -- Astrocytoma, cytological findings -- Atypia, chemotherapy-associated -- Atypical glandular cells -- Atypical immature metaplasia -- Barrett`s esophagus, cytological findings -- Basal cell adenoma of salivary gland, cytological findings -- Basal cell carcinoma of the orbit and ocular adnexa -- Benign, non-neoplastic lesions and inflammatory process of the orbit -- Biliary duct brushing -- Bladder wash specimen -- Bone cysts, cytological findings -- Breast cysts, cytological findings -- Bronchial washing -- Bronchoalveolar lavage specimen -- Carcinoid, cytological findings -- Carcinoma ex Pleomorphic adenoma, cytological findings -- Cat-scratch disease, cytological findings -- Cell-blocks -- Cerebrospinal fluid, cytology of haematopoietic malignancies -- Cerebrospinal fluid, cytology of infections -- Cerebrospinal fluid, cytology of metastatic malignancies -- Cerebrospinal fluid, cytology of SNC tumours -- Cerebrospinal fluid, normal cytology -- Cholangiocarcinoma, cytological findings -- Chordomas, cytological findings -- Chromophobe renal cell carcinoma, cytological findings -- Cirrhosis, cytological findings -- Clear cell sarcoma, cytological findings -- Colloid goiter, cytological findings -- Congenital mesoblastic nephroma, cytological findings -- Conjunctiva general aspects -- Conjunctival inflammatory lesions -- Conjunctival lymphoma -- Conjunctival melanocytic tumours -- Conjunctival papilloma -- Conjunctival squamous cell carcinoma -- Cornea cytology -- Curschmann`s spiral -- Cyst of salivary gland, cytological findings -- Cytology of the orbit and ocular adnexa -- Cytomegalovirus, cytological findings -- Cytospin -- Ductal breast carcinoma, cytological findings -- Ductal carcinoma of salivary gland, cytological findings -- Effusions associated with pneumonia -- Effusions associated with rheumatoid arthritis (RA) -- Effusions associated with systemic lupus erythematosus (SLE) -- Endocervical adenocarcinoma, in situ -- Endocervical adenocarcinoma, invasice -- Endometrial cells, smears -- Endometrioid ovarian tumors, cytological findings -- Endometriosis, cytological findings -- Eosinophilic effusions -- Ependymoma, cytological findings -- Epithelial proliferative benign lesion of the breast -- Epithelial proliferative lesion of the breast -- Epithelial-myoepithelial carcinoma of salivary gland, cytological findings -- Epithelioid sarcomas, cytological findings -- Extrauterine adenocarcinoma, cytological findings -- Eyelids cytology general aspects -- Fat necrosis, cytological findings -- Ferruginous bodies -- Fibroadenoma, cytological findings -- Fibromatosis, cytological findings -- Fine needle aspiration cytology -- Flow cytometry on FMA material -- Follicular tumor, cytological findings -- Fungi infections, cytological findings -- Germ cell neoplasias, cytological findings -- Giant cell tumours of the bone, cytological findings -- Granular cell tumor, cytological findings -- Granulomatous lymphadenitis, cytological findings -- Granulomatous thyroiditis, cytological findings -- Granulosa cell tumor of ovary, cytological findings -- Gynecomastia, cytological findings -- Hashimoto thyroiditis, cytological findings -- Hepatoblastoma, cytological findings -- Hepatocellular carcinoma, cytological findings -- Herpes virus, cytological findings -- High grade urothelial cell carcinoma, cytological findings -- Hodgkin`s disease, cytological findings -- Human papillomavirus -- Human polyomavirus, cytological findings -- Hurthle cell tumors, cytological findings -- Hyalinizing trabecular adenoma, cytological findings -- Infectious mononucleosis, cytological findings -- Inflammatory pseudo tumours of the orbit and ocular adnexa -- Kikuchi lymphadenitis, cytological findings -- Lachrymal gland tumours of the orbit and ocular adnexa -- Lachrymal glands malignant tumours of the orbit and ocular adnexa -- Langerhans cell histiocytosis, cytological findings -- Liquid-based cytology -- Liver metastasis, cytological findings -- Lobular breast carcinoma, cytological findings -- Low-grade papillary urothelial cell carcinoma, cytological findings -- Lung metastasis, cytological findings -- Lypoma, cytological findings -- Malakoplakia, cytological findings -- Malignant melanoma of the orbit and ocular adnexa -- Mediastinal tumor, fine needle aspiration -- Medullary breast carcinoma, cytological findings -- Medullary carcinoma of thyroid, cytological findings -- Medulloblastoma, cytological findings -- Melanoma, cytological findings.- Meningioma of the orbit and ocular adnexa.- Meningioma, cytological findings -- Mesothelial cells, reactive -- Mesothelioma, effusions -- Metanephric adenoma, cytological findings -- Metaplastic breast carcinoma, cytological findings -- Metastatic adenocarcinoma, effusions -- Microglandular hyperplasia -- Molecular techniques on cytology -- Mucinous breast carcinoma, cytological findings -- Mucinous ovarian tumors, cytological findings -- Mucoepidermoid carcinoma, cytological findings -- Myxoid sarcomas, cytological findings -- Negative for intraepithelial lesions, cytological findings -- Neuroblastoma, cytological findings -- Neuroendocrine carcinoma, cytological findings -- Nodular hyperplasia of prostate, cytological findings -- Nodular hyperplasia of thyroid, cytological findings -- Non-Hodgkin lymphomas, cytological findings -- Oligodendroglioma, cytological findings -- Orbit cytology general aspects -- Orbital cysts of the orbit and ocular adnexa -- Orbital malignant lymphoma of the orbit and ocular adnexa -- Orbital malignant tumours of the orbit and ocular adnexa -- Orbital metastases of the orbit and ocular adnexa -- Orbital soft tissue tumours of the orbit and ocular adnexa -- Osteosarcoma, cytological findings -- Other benign orbital tumours of the orbit and ocular adnexa -- Ovarian non-neoplastic cysts, cytological findings -- Pancreatic ductal adenocarcinoma (cytological aspects) -- Pancreatic intraductal papillary mucinous neoplasm (cytological aspects) -- Pancreatic lymphoepithelial cyst (cytological aspects) -- Pancreatic mucinous cystic neoplasm (cytological aspects) -- Pancreatic mucinous, noncystic adenocarcinoma (colloid carcinoma) (cytological aspects) -- Pancreatic neuroendocrine tumor (cytological aspects) -- Pancreatic pseudocyst (cytological aspects) -- Pancreatic serous cystadenoma (cytological aspects) -- Pancreatic solid-pseudopapillary neoplasm (cytological aspects) -- Papillary carcinoma of thyroid, cytological findings.-Papillary renal cell carcinoma, cytological findings -- Papillary tumors of the breast, cytological findings -- Penile neoplasias, cytological findings -- Pericardial effusions, cytological findings -- Peritoneal effusions, cytology -- Perotoneal Washings (PW) -- Pheochromocytoma,cytological findings -- Phyllodes tumor, cytological findings -- Plasmocytomas, cytological findings -- Pleomorphic adenoma of the orbit and ocular adnexa -- Pleomorphic adenoma, cytological findings -- Pleomorphic sarcomas, cytological findings -- Pleural effusions, cytology -- Pneumocystis jirovecci, cytological findings.- Polymorphous low grade adenocarcinoma, cytological findings -- Poorly differentiated carcinoma of thyroid, cytological findings -- Primitive neuroectodermal tumours (PNET), cytological findings -- Prostate adenocarcinoma, cytological findings -- Prostatitis, cytological findings -- Reactive cellular changes, infections -- Reactive cellular changes, intrauterine contraceptive device -- Reactive cellular changes, repair -- Reactive lymphoid hyperplasia, cytological findings -- Renal cell carcinoma, cytological findings.- Renal oncocytoma, cytological findings -- Reserve cell hyperplasia -- Rhabdoid tumor, cytological findings -- Rhabdomyosarcoma, cytological findings -- Rosai-Dorfman diesase, cytological findings -- Round cell sarcomas, cytological findings -- Schwannoma, cytological findings -- Sebaceous carcinoma of the orbit and ocular adnexa -- Secretory carcinoma, cytological findings -- Serous ovarian tumors, cytological findings -- Sex-cord stromal tumors, cytological findings -- Small cell carcinoma, cytological findings -- Spindle cell sarcomas, cytological findings -- Squamous cell carcinoma, in situ -- Squamous cell carcinoma of the orbit and ocular adnexa -- Squamous cell carcinoma, effusions -- Squamous cell carcinoma, invasive -- Squamous intraepithelial lesion, high grade (HGSIL) -- Squamous intraepithelial lesion, low grade (LGSIL) -- Squamous metaplasia -- Squamous papilloma of the orbit and ocular adnexa -- Subareolar abscess, cytological findings -- Systemic Disease and Effusions, Cytology of -- Thymomas, cytological findings -- Toxoplasmosis, cytological findings -- Transitional cell/urothelial carcinoma, cytological findings -- Tuberculous effusions -- Undifferentiated carcinoma of the pancreas (cytological aspects) -- Undifferentiated carcinoma with osteoclast-type giant cells of the pancreas (cytological aspects) -- Urine specimen, cytology -- Viral infections, cytological findings -- Warthin tumor, cytological findings.

Format: e-Book

Publication Type: Encyclopedia

Location: Online

Atlas of Infectious Disease Pathology

https://libcat.nshealth.ca/en/permalink/provcat41755

Bryan H. Schmitt, editors. --Cham: Springer , 2017.

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Location: Online

Infectious diseases may be encountered in nearly every aspect of pathology. This atlas provides an informative reference for the identification of the common and esoteric pathogens, presenting in a wide array of specimen types. The focus of the presented images is on the hematoxylin and eosin-stained appearances of these infections and highlight common special stains that can be used to aid in the diagnosis of the infectious agent. Where appropriate, commentary regarding additional testing such…

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Other Authors: Schmitt, Bryan H.

Responsibility: Bryan H. Schmitt, editors

Place of Publication: Cham

Publisher: Springer

Date of Publication: 2017

Physical Description: 1 online resource (xiv, 258 pages) : 418 illus., 417 illus. in color

Series Title: Atlas of anatomic pathology

ISBN: 9783319547022; 9783319547015 (print ed.)

Subjects (MeSH): Communicable Diseases - pathology

Abstract: Infectious diseases may be encountered in nearly every aspect of pathology. This atlas provides an informative reference for the identification of the common and esoteric pathogens, presenting in a wide array of specimen types. The focus of the presented images is on the hematoxylin and eosin-stained appearances of these infections and highlight common special stains that can be used to aid in the diagnosis of the infectious agent. Where appropriate, commentary regarding additional testing such as immunohistochemistry and molecular-based methods is supplied. The Atlas of Infectious Disease Pathology is organized primarily by pathogen type followed by discussion of the various manifestations that may occur in individual organ systems. The reader will be provided with a comprehensive overview of the histopathology of the majority of infectious diseases encountered in general and subspecialty practice alike.

Contents: An Introduction to Infections Disease Pathology -- Bacterial Infections -- Viral Infections -- Fungal Infections -- Parasitic Infections -- Mimics and Artifacts.

Format: e-Book

Publication Type: Atlas

Location: Online

Metabolism in Cancer

https://libcat.nshealth.ca/en/permalink/provcat40307

Thorsten Cramer, Clemens A. Schmitt, editors. --Cham: Springer , c2016.

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Location: Online

This textbook presents concise chapters written by internationally respected experts on various important aspects of cancer-associated metabolism, offering a comprehensive overview of the central features of this exciting research field. The discovery that tumor cells display characteristic alterations of metabolic pathways has significantly changed our understanding of cancer: while the first description of tumor-specific changes in cellular energetics was published more than 90 years ago, the…

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Other Authors: Cramer, Thorsten; A. Schmitt, Clemens

Responsibility: Thorsten Cramer, Clemens A. Schmitt, editors

Place of Publication: Cham

Publisher: Springer

Date of Publication: c2016

Physical Description: 1 online resource (ix, 266 p. : 31 illus., 25 illus. in color)

Series Vol.: 207

Series Title: Recent results in cancer research

ISBN: 9783319421186; 9783319421162 (print ed.)

ISSN: 0080-0015

Subjects (MeSH): Neoplasms - genetics; Neoplasms - metabolism; Neoplastic Processes

Abstract: This textbook presents concise chapters written by internationally respected experts on various important aspects of cancer-associated metabolism, offering a comprehensive overview of the central features of this exciting research field. The discovery that tumor cells display characteristic alterations of metabolic pathways has significantly changed our understanding of cancer: while the first description of tumor-specific changes in cellular energetics was published more than 90 years ago, the causal significance of this observation for the pathogenesis of cancer was only discovered in the post-genome era. The first 10 years of the twenty-first century were characterized by rapid advances in our grasp of the functional role of cancer-specific metabolism as well as the underlying molecular pathways. Various unanticipated interrelations between metabolic alterations and cancer-driving pathways were identified and currently await translation into diagnostic and therapeutic applications. Yet the speed, quantity, and complexity of these new discoveries make it difficult for researchers to keep up to date with the latest developments, an issue this book helps to remedy.

Contents: The Role of Glucose and Lipid Metabolism in Growth and Survival of Cancer Cells -- Lactate—An Integrative Mirror of Cancer Metabolism -- Metabolic Reprogramming by the PI3K-Akt-mTOR Pathway in Cancer -- MYC, Metabolic Synthetic Lethality, and Cancer -- The Role of pH Regulation in Cancer Progression -- Metabolic Features of Cancer Treatment Resistance -- Tissue-Based Metabolomics to Analyze the Breast Cancer Metabolome -- Imaging of Tumor Metabolism Using Positron Emission Tomography (PET) -- Quantitative Analysis of Cancer Metabolism: From pSIRM to MFA -- Mathematical Modeling of Cellular Metabolism -- Ketogenic Diet and Cancer—a Perspective -- Fasting and Caloric Restriction in Cancer Prevention and Treatment.

Format: e-Book

Location: Online

Molecular pathology : a practical guide for the surgical pathologist and cytopathologist

https://libcat.nshealth.ca/en/permalink/provcat34800

edited by John M.S. Bartlett, Abeer Shaaban, Fernando Schmitt. --Cambridge, UK: Cambridge University Press , 2015.

Call Number: QZ 50 M718 2015

Location: Dickson Building

"This practical manual provides a comprehensive yet concise guide to state-of-the-art molecular techniques and their applications. It starts with an overview of the essential principles of molecular techniques, followed by separate chapters detailing the use of these techniques in particular tissues and organs, and describing recommended treatment plans. Each chapter covers the tests available, their advantages, limitations, and use as diagnostic and prognostic tools, with key learning points a…

Call Number: QZ 50 M718 2015

Other Authors: Bartlett, John M.S.; Shaaban, Abeer; Schmitt, Fernando

Responsibility: edited by John M.S. Bartlett, Abeer Shaaban, Fernando Schmitt

Place of Publication: Cambridge, UK

Publisher: Cambridge University Press

Date of Publication: 2015

Physical Description: xix, 396 pages

Series: Cambridge medicine

Series Title: Cambridge medicine (Series)

ISBN: 9781107443464

Subjects (MeSH): Pathology, Molecular - methods; Molecular Diagnostic Techniques - methods

Abstract: "This practical manual provides a comprehensive yet concise guide to state-of-the-art molecular techniques and their applications. It starts with an overview of the essential principles of molecular techniques, followed by separate chapters detailing the use of these techniques in particular tissues and organs, and describing recommended treatment plans. Each chapter covers the tests available, their advantages, limitations, and use as diagnostic and prognostic tools, with key learning points at the end of each topic. Using both histologic and cytologic samples, it discusses how to interpret test results in a pathologic context and enables trainees and practising pathologists to gain an in-depth understanding of molecular diagnostic techniques and how to incorporate them into routine diagnostic practice. Aiding the daily practice of refining diagnosis, as well as offering a didactic approach, this book is an essential reference for practising pathologists and cytopathologists as well as trainees in pathology"--Provided by publisher.

Contents: Preface -- 1. An introduction to molecular pathology / John M. S. Bartlett -- 2. Molecular regulation of cellular function / Marsela Braunstein and John M. S. Bartlett -- 3. Practical application of molecular techniques in diagnostic histopathology and cytopathology and clinical management / Abeer Shaaban and Fernando Schmitt -- 4. Fluorescent and non-fluorescent in situ hybridization / Jane Bayani and John M. S. Bartlett -- 5. Clinical applications of the polymerase chain reaction for molecular pathology / Angela B. Y. Hui, Annette D. Wong and Carlo V. Hojilla -- 6. Are microarrays ready for prime time? / Jane Bayani and John M. S. Bartlett -- 7. Tissue microarrays / Luigi Tornillo -- 8. Sequencing / Andrew M. K. Brown, Philipe C. Zuzarte and Paul M. Krzyzanowski -- 9. Microsatellite instability in colorectal cancer / Maria Sofia Fernandes, Raquel Seruca and Se;rgia Velho -- 10. Mutational analysis / Aaron R. Hansen, Mahadeo A. Sukhai, Hal K. Berman, Suzanne Kamel-Reid and Philippe L. Bedard -- 11. Tumors of the breast / Cathy B. Moelans, Petra van der Groep, Robert Kornegoor, Jelle Wesseling and Paul J. van Diest -- 12. Tumors of the female genital system / Adhemar Longatto Filho, Sigurd F. Lax and Bin Yang -- 13. Tumours of the male urogenital system / Kirsten D. Mertz and Lukas Bubendorf -- 14. Tumors of the gastrointestinal system / Manuel Salto-Tellez, Benedict Yan, Roseann I. Wu and Martha Bishop Pitman -- 15. Soft tissue, bone and skin tumours / Stamatios Theocharis and Jerzy Klijanienko -- 16. Cardio-thoracic tumors / Umberto Malapelle, Claudio Bellevicine, Elena Vigliar and Giancarlo Troncone -- 17. Tumors of the endocrine system / Sylvia L. Asa and Ozgur Mete -- 18. Haematological malignancies of the lymph nodes / Sarah E. Coupland and Pedro Farinha -- 19. Pediatric tumors / Paul Roberts, Susan Picton and Jens Stahlschmidt -- 20. Serous effusions / Ben Davidson -- 21. Academic applications and future of molecular pathology / Manuel Salto-Tellez and Benedict Yan -- Index.

Format: Book

Location: Dickson Building

Copies: 1

Loan Period: 3 weeks

Fine needle aspiration cytology of the breast : atlas of cyto-histologic correlates

https://libcat.nshealth.ca/en/permalink/provcat32623

Gary Tse, Puay Hoon Tan, Fernando Schmitt, authors. --Berlin, Heidelberg: Springer , c2013.

Available Online: View e-Book

Location: Online

This book provides a detailed update on all aspects of fine-needle aspiration cytology of breast lesions. It will serve readers as an up-to-date reference and atlas on both new entities in breast pathology, including borderline lesions such as flat epithelial atypia, and the classic benign and malignant lesions. Throughout, emphasis is placed on the characteristic diagnostic features as well as the common pitfalls faced by cytologists. As cytologic features can be highly variable, correspondin…

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Other Authors: Tse, Gary; Tan, Puay Hoon; Schmitt, Fernando

Responsibility: Gary Tse, Puay Hoon Tan, Fernando Schmitt, authors

Place of Publication: Berlin, Heidelberg

Publisher: Springer

Date of Publication: c2013

Physical Description: 1 online resource (xviii, 192 p. : 167 ill., 165 ill. in color)

ISBN: 9783642350009

Subjects (MeSH): Biopsy, Fine-Needle - methods; Breast diseases - diagnosis; Breast - anatomy & histology; Breast - cytology

Subjects (LCSH): Medicine; Gynecology; Oncology; Pathology

Abstract: This book provides a detailed update on all aspects of fine-needle aspiration cytology of breast lesions. It will serve readers as an up-to-date reference and atlas on both new entities in breast pathology, including borderline lesions such as flat epithelial atypia, and the classic benign and malignant lesions. Throughout, emphasis is placed on the characteristic diagnostic features as well as the common pitfalls faced by cytologists. As cytologic features can be highly variable, corresponding cytology and histology images are displayed together, enabling readers to gain a good understanding of the morphologic features of various lesions. Core-needle biopsy and fine-needle aspiration cytology are compared in depth, with attention to their relative strengths and weaknesses and indications. In addition, the impact of molecular classification of breast cancers on cytologic diagnosis is explored, and the use of molecular techniques in diagnostic cytology is discussed.

Contents: Physiology of the Breast -- Basic Pathology of the Breast -- Aspiration Techniques including Ultrasound guided Aspiration -- Liquid based Cytology in Breast Lesions -- Cell Block -- Fibrocystic Changes and Cysts -- Fibroadenomas and Diagnostic Pitfalls -- other Fibroepithelial Lesions -- Atypical Epithelial Proliferation including columnar Cell Changes -- Papillary Lesions -- Mucinous Lesions -- Carcinoma and Variants -- Axillary Lymph Node -- Aspirate – intra-operative Imprint Cytology -- Axillary Lymph node Aspirate – Ultrasound guided Aspiration -- Special Ancillary Techniques - Immunohistochemistry in Cell Block -- Special Ancillary Techniques - Molecular Studies -- Comparison of Aspiration and Core Needle Biopsy -- Future Directions -- Index.