Fetal Morph Functional Diagnosis
https://libcat.nshealth.ca/en/permalink/provcat46487
Hideaki Masuzaki, editor.
--Singapore:
Springer
, c2021.
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- NEW Springer 2021
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- Online
This book explores the recent clinical and research findings in the field of prenatal screening and diagnosis. It presents new devices and tests such as real-time 3D ultrasound, ultrafast fetal MRI, and next-generation sequencing and discusses genetic counseling and fetal therapy. Written by pioneering scientists, the book is divided into six themed parts: ultrasound examination, genetic tests, genetic disorders, chromosomal diseases, genetic counseling, and techniques, presenting carefully pre…
- Available Online
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- Other Authors
- Masuzaki, Hideaki
- Responsibility
- Hideaki Masuzaki, editor
- Place of Publication
- Singapore
- Publisher
- Springer
- Date of Publication
- c2021
- Physical Description
- 1 online resource (ix, 354 p.) : 108 illus., 60 illus. in color
- Series Title
- Comprehensive gynecology and obstetrics
- ISBN
- 9789811581717
- 9789811581700 (Print ed.)
- 9789811581724 (Print ed.)
- 9789811581731 (Print ed.)
- ISSN
- 2364-1932
- Subjects (MeSH)
- Chromosome Disorders
- Fetus - abnormalities
- Genetic Counseling
- Prenatal Diagnosis - methods
- Specialty
- Embryology
- Reproductive Medicine
- Abstract
- This book explores the recent clinical and research findings in the field of prenatal screening and diagnosis. It presents new devices and tests such as real-time 3D ultrasound, ultrafast fetal MRI, and next-generation sequencing and discusses genetic counseling and fetal therapy. Written by pioneering scientists, the book is divided into six themed parts: ultrasound examination, genetic tests, genetic disorders, chromosomal diseases, genetic counseling, and techniques, presenting carefully prepared original data.This thought-provoking, instructive and informative book is intended for geneticists, obstetricians, pediatricians, genetic counselors and nurses. Although the incidence of congenital abnormalities such as structural, chromosomal and genetic disorders is very low, it is important to have accurate information on their incidence and likely outcome, and on the screening and diagnosis of congenital abnormalities during pregnancy care. This book provides valuable insights into prenatal screening, genetic counseling and fetal diagnosis.
- Contents
- Part I. Ultrasound Examination -- 1. Ultrasonic Screening -- 2. Abnormal Findings in Ultrasound Examination -- 3. Fetal MRI -- Part II. Genetic Tests -- 4. Prenatal Screening for Fetal Aneuploidy -- 5. Diagnostic Tests (Invasive Procedures) -- Part III. Genetic Disorders -- 6. Mendelian Disease -- 7. Neuroimaging and Genetics in Brain Maldevelopment -- 8. Muscular Dystrophy -- 9. Skeletal Dysplasia 10. Genitourinary Tract Abnormalities -- 11. Genomic Imprinting Disorders (Including Mesenchymal Placental Dysplasia) -- 12. Genetics in Multiple Gestation -- 13. Fetal Therapy -- Part IV. Chromosomal Diseases -- 14. General Remarks About Autosomal Diseases -- 15. Sex Chromosome-Linked Diseases -- Part V. Genetic Counseling -- 16. Fetal Anomaly and Genetic Counseling -- 17. Soft Marker Test (NT, Nasal Bone, Etc.) and Genetic Counseling -- 18. Noninvasive Prenatal Testing and Genetic Counseling -- 19. Trisomy and Genetic Counseling -- 20. Sex Chromosome Abnormalities and Genetic Counseling -- 21. Genetic Counseling: Chromosomal Structural Rearrangements -- 22. Gene Disorders and Genetic Counseling -- Part VI. Technical -- 23. G-Banding: Fetal Chromosome Analysis by Using Chromosome Banding Techniques -- 24. FISH -- 25. Polymerase Chain Reaction (PCR) -- 26. Microarray and Next Generation Sequencing -- 27. How to Obtain Certifications and Licenses for Prenatal Diagnosis.
- Access
- NEW Springer 2021
- Format
- e-Book
- Location
- Online
Frontiers in Ovarian Cancer Science
https://libcat.nshealth.ca/en/permalink/provcat41990
Hidetaka Katabuchi, editor.
--Singapore:
Springer
, 2017.
- Available Online
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- Location
- Online
This volume presents the latest advances and the current status of our understanding regarding ovarian cancer, addressing both the basic and clinical aspects of the disease. In terms of basic medicine, the WHO Classification of Tumors of Female Reproductive Organs was revised in 2014, and that version addresses several new concepts and histopathological classifications not previously included. One of the most revolutionary breakthroughs concerns the genesis of epithelial ovarian tumors, shiftin…
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- Other Authors
- Katabuchi, Hidetaka
- Responsibility
- Hidetaka Katabuchi, editor
- Place of Publication
- Singapore
- Publisher
- Springer
- Date of Publication
- 2017
- Physical Description
- 1 online resource (viii, 314 pages) : 78 illus., 67 illus. in color
- Series Title
- Comprehensive gynecology and obstetrics
- ISBN
- 9789811041600
- 9789811041594 (print ed.)
- ISSN
- 2364-1932
- Subjects (MeSH)
- Ovarian Neoplasms
- Abstract
- This volume presents the latest advances and the current status of our understanding regarding ovarian cancer, addressing both the basic and clinical aspects of the disease. In terms of basic medicine, the WHO Classification of Tumors of Female Reproductive Organs was revised in 2014, and that version addresses several new concepts and histopathological classifications not previously included. One of the most revolutionary breakthroughs concerns the genesis of epithelial ovarian tumors, shifting the focus from the ovarian surface epithelium to serous tubal intraepithelial carcinomas. Clinically, the mortality rate of epithelial ovarian cancer has gradually increased over the past few decades, making it essential to pursue multidisciplinary treatment and apply novel techniques such as neoadjuvant chemotherapy in daily clinical practice. The primary clinical task is the effective treatment of recurrent ovarian cancer with early palliative medicine. Fertility-sparing surgery may also be pursued depending on histologic subtypes, stage, extent of disease, and preexisting ovarian reserve with the concept of oncofertility. On the basis of the considerations described above, each expert author elucidates the science of ovarian cancer in detail, thus providing a collection that will benefit young medical oncologists and seasoned gynecologists and obstetricians alike.
- Contents
- 1. Epidemiology and Etiology of Ovarian Cancer -- 2. Hereditary Ovarian Cancer -- 3. Morphologic and Molecular Pathogenesis -- 4. Screening and Prevention of Ovarian Cancer -- 5. Pathology of Epithelial Ovarian Tumors -- 6. Pathology of Non-epithelial Ovarian Tumors -- 7. Ovarian Cancer Genome and Molecular Experimental Sciences -- 8. Strategies for the Management of Epithelial Ovarian Cancer -- 9. Strategies for the Management of Epithelial Ovarian Borderline Tumors -- 10. Strategies for the Management of Non-epithelial ÇÇOvarian Tumors -- 11. Primary Surgical Treatment of Epithelial Ovarian Cancer -- 12. Primary Chemotherapy and Targeted Molecular Therapy of Epithelial Ovarian Cancer -- 13. Immunotherapy of Epithelial Ovarian Cancer -- 14. Treatment of Recurrent Epithelial Ovarian Cancer -- 15. Management of Adolescent Ovarian Cancer -- 16. Management of Ovarian Cancer in the Elderly Population -- 17. Palliative Medicine in the Management of Ovarian Cancer.
- Format
- e-Book
- Location
- Online
Precision Medicine in Gynecology and Obstetrics
https://libcat.nshealth.ca/en/permalink/provcat41960
Ikuo Konishi, editor.
--Singapore:
Springer
, 2017.
- Available Online
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- Location
- Online
This volume presents the scientific advances and current status of our understanding of precision medicine for common diseases in gynecology and obstetrics. Standard treatments based on clinical guidelines in the field have been established for decades, and those are essential to daily clinical practice. Meanwhile comprehensive genomic and genetic analyses have led to personalized medicine by precise clinical and genomic approaches. This book is organized into two major parts, gynecology and ob…
- Available Online
- View e-Book
- Other Authors
- Konishi, Ikuo
- Responsibility
- Ikuo Konishi, editor
- Place of Publication
- Singapore
- Publisher
- Springer
- Date of Publication
- 2017
- Physical Description
- 1 online resource (viii, 250 pages) : 47 illus., 41 illus. in color
- Series Title
- Comprehensive gynecology and obstetrics
- ISBN
- 9789811024894
- 9789811024887 (print ed.)
- ISSN
- 2364-1932
- Subjects (MeSH)
- Genital Neoplasms, Female - therapy
- Precision Medicine - methods
- Pregnancy Complications - therapy
- Abstract
- This volume presents the scientific advances and current status of our understanding of precision medicine for common diseases in gynecology and obstetrics. Standard treatments based on clinical guidelines in the field have been established for decades, and those are essential to daily clinical practice. Meanwhile comprehensive genomic and genetic analyses have led to personalized medicine by precise clinical and genomic approaches. This book is organized into two major parts, gynecology and obstetrics, and the chapters in each part give a clear exposition of the current knowledge and the future perspectives for the treatment of various gynecological cancers, maternal disorders, and other diseases that affect female patients. Topics on novel treatment strategy with the application of molecular targeted drugs, immunotherapy, and prevention medicine are also covered. This collection benefits not only experienced gynecologists and obstetricians, but also young physicians who would like to begin clinical and basic research on diseases in women, researchers in basic medicine, and all medical oncologists who are involved in gynecological cancers.
- Contents
- Part 1: Introduction -- 1. Toward Precision Medicine in Gynecology and Obstetrics -- Part 2: Gynecology -- 2. Genomics in Gynecological Cancer: Future Perspective -- 3. Signal Transduction and Targeted Therapy for Gynecologic Cancer -- 4. Immune Therapy for Gynecologic Cancer: Coming True -- 5. Prevention of Cervical Cancer: Era of HPV Testing and Vaccination -- 6. Pathology, Genomics, and Treatment of Endometrial Cancer -- 7. Diversity in Pathology and Genomics in Ovarian Cancer -- 8. Hereditary Ovarian and Endometrial Cancers: Current Management -- 9. Molecular Pathology and Novel Therapy for Uterine Sarcomas -- Part 3:Obstetrics -- 10. Recurrent Pregnancy Loss: Current Evidence and Clinical Guideline -- 11. Genomic Approach for Recurrent Abortions: Prevention Feasible? -- 12. Prenatal Diagnosis of Embryo and Fetus in the Human -- 13. Pathology and Genomics in Gestational Trophoblastic Neoplasia -- 14. Genomic Analysis for Hypertension in Pregnancy -- 15. Molecular Mechanisms for Preterm Delivery -- 16. Developmental Origins for Health and Disease (DOHaD): Future Perspective.
- Format
- e-Book
- Location
- Online
Preeclampsia : Basic, Genomic, and Clinical
https://libcat.nshealth.ca/en/permalink/provcat43089
Shigeru Saito, editor.
--Singapore:
Springer
, c2018.
- Available Online
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- Location
- Online
This volume is an excellent guide that comprehensively illustrates hypertensive disorders of pregnancy, especially preeclampsia, in both the basic and clinical aspects. Preeclampsia is a pregnancy-specific multi-organ disorder and a leading cause of maternal and neonatal mortality. The pathophysiology of pregnancy-specific disorders was long unknown, but recently many new findings have been reported from the point of view of pathophysiology. Furthermore, this complication of pregnancy, especial…
- Available Online
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- Other Authors
- Saito, Shigeru
- Responsibility
- Shigeru Saito, editor
- Alternate Title
- Pre-eclampsia
- Place of Publication
- Singapore
- Publisher
- Springer
- Date of Publication
- c2018
- Physical Description
- 1 online resource (viii, 290 p.) : 54 illus., 32 illus. in color
- Series Title
- Comprehensive gynecology and obstetrics
- ISBN
- 9789811058912
- 9789811058905 (print ed.)
- 9789811058929 (print ed.)
- ISSN
- 2364-1932
- Subjects (MeSH)
- Pre-Eclampsia
- Specialty
- Obstetrics
- Abstract
- This volume is an excellent guide that comprehensively illustrates hypertensive disorders of pregnancy, especially preeclampsia, in both the basic and clinical aspects. Preeclampsia is a pregnancy-specific multi-organ disorder and a leading cause of maternal and neonatal mortality. The pathophysiology of pregnancy-specific disorders was long unknown, but recently many new findings have been reported from the point of view of pathophysiology. Furthermore, this complication of pregnancy, especially preeclampsia, is a potent risk factor for chronic conditions such as cardiovascular disease, diabetes mellitus, kidney disease, and hypertension. The book is composed of seven parts including genetic background, pathology, pathophysiology, and the latest prediction and treatment of preeclampsia. Specific basic topics such as immunological maladaptation, placental adenosine signaling, and new prediction markers are also expounded by experts. Thus it benefits not only obstetricians, pediatricians, nephrologists, diabetologists, and cardiologists, but also immunologists, endocrinologists, geneticists, pathologists, biologists, and molecular biologists who are interested in the treatment of hypertension in pregnancy.
- Contents
- Part I. Risk Factors for Preeclampsia -- 1. Risk Factors for Preeclampsia -- Part II. Genetic Background in Preeclampsia -- 2. Genetic Background of Preeclampsia -- Part III Pathological Findings in Preeclampsia -- 3. Trophoblast Invasion: Remodelling of Spiral Arteries and Beyond -- Part IV. Pathophysiology of Preeclampsia -- 4. Immunological Maladaptation -- 5. Glucose Intolerance and Insulin Resistance: Relevance in Preeclampsia -- 6. Placental Adenosine Signaling in the Pathophysiology of Preeclampsia -- 7. Obesity, Adipokines, and Lipokines -- 8. Autophagy in Preeclampsia -- 9. Animal Models in Preeclampsia -- 10. The Differences Between Early- and Late-Onset Pre-eclampsia -- Part V Prediction of Preeclampsia -- 11. sFlt-1/PLGF -- 12. Ambulatory Blood Pressure Measurement and Home Blood Pressure Measurement -- 13. MicroRNA -- Part VI. Therapy -- 14. Novel Therapies for Preeclampsia -- 15. Pravastatin for Preeclampsia Prevention and Treatment -- 16. Prevention and Treatment of Stroke and Eclampsia -- Part VII. The Risk of Cardiovascular Events in Preeclamptic Cases -- 17. Cardiovascular Disease Following Hypertensive Pregnancy.
- Format
- e-Book
- Location
- Online
Preterm Labor and Delivery
https://libcat.nshealth.ca/en/permalink/provcat44854
Hiroshi Sameshima, editor.
--Singapore:
Springer
, c2020.
- Available Online
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- Location
- Online
This splendid volume presents numerous aspects of preterm labor and delivery, from its fundamental mechanism to clinically focused approaches. The incidence of preterm delivery is 6-7% in Japan, while globally up to 10% of pregnancies with preterm labor result in premature delivery. The rates of overall survival and intact survival of the premature infants are also excellent in Japan. Thus Japan’s approach to preterm labor and delivery has long attracted attention. In each chapter, experts desc…
- Available Online
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- Other Authors
- Sameshima, Hiroshi
- Responsibility
- Hiroshi Sameshima, editor
- Place of Publication
- Singapore
- Publisher
- Springer
- Date of Publication
- c2020
- Physical Description
- 1 online resource (viii, 252 p.) : 47 illus., 33 illus. in color
- Series Title
- Comprehensive gynecology and obstetrics
- ISBN
- 9789811398759
- 9789811398742 (Print ed.)
- 9789811398766 (Print ed.)
- 9789811398773 (Print ed.)
- ISSN
- 2364-1932
- Subjects (MeSH)
- Delivery, Obstetric
- Infant, Premature
- Obstetric Labor, Premature
- Specialty
- Obstetrics
- Perinatology
- Abstract
- This splendid volume presents numerous aspects of preterm labor and delivery, from its fundamental mechanism to clinically focused approaches. The incidence of preterm delivery is 6-7% in Japan, while globally up to 10% of pregnancies with preterm labor result in premature delivery. The rates of overall survival and intact survival of the premature infants are also excellent in Japan. Thus Japan’s approach to preterm labor and delivery has long attracted attention. In each chapter, experts describe specific issues unique to conditions in Japan, including diagnosis, tocolytic agents, definition of clinical chorioamnionitis, treatment of bacterial vaginosis, role of amniocentesis, management of preterm premature membrane rupture and also placental pathology, presenting definitive evidence of the reduced incidence of preterm delivery in Japan. This book benefits not only obstetricians, pediatricians and gynecologist, but also midwives, nurse practitioners, and medical and associated staffs in the field of obstetrics, pediatrics, as well as neonatal and perinatal medicine who are involved in delivery.
- Contents
- Part I. Preterm labor: A challenge -- 1. Preterm labor: impacts on perinatal ecology -- 2. Definition and diagnosis of preterm labor -- 3. Epidemiology and incidence of preterm delivery -- Part II. Preterm labor and intrauterine infection and inflammation -- 4. Subclinical intrauterine infection -- 5. Clinical and subclinical intrauterine infection/inflammation -- 6. Cervical changes 1: morphological and biochemical changes -- 7. Cervical changes 2 : USG findings -- Part III. Other mechanisms related to preterm labor -- 8. Multiple mechanisms of preterm labor other than intrauterine infection -- 9. Abruption and preterm labor -- Part IV. Prevention, Treatment, and Management -- 10. Prevention and Tocolytic agents 1 -- 11. Prevention and Tocolytic agents 2 -- 12. Tocolytic agent 3 -- 13. Antibiotics for preterm labor -- 14. Probiotics for preterm labor -- 15. Progesterone -- 16. Cerclage 1: general -- 17. Cerclage 2: abdominal vs vaginal -- 18. Bacterial vaginosis -- 19. Antenatal corticosteroid -- 20. Mode of delivery of premature infants -- 21. Management of pPROM in general -- 22. Prevention of PTB: meta-analysis -- Part V. Preterm Newborn -- 23. The preterm newborn: Morbidity and Mortality -- Part VI. Placental Pathology 24. Placental pathology -- Part VII. Research Frontier -- 25. Genetic analysis of spontaneous preterm birth.
- Format
- e-Book
- Location
- Online
Surgery for Gynecologic Cancer
https://libcat.nshealth.ca/en/permalink/provcat44246
Mikio Mikami, editor.
--Singapore:
Springer
, 2019.
- Available Online
- View e-Book
- Location
- Online
This comprehensive volume provides exhaustive interpretations of surgery for gynecologic cancer. In these chapters, expert authors expound the history, principles and indications, preoperative evaluations, techniques, morbidity, and the future prospects for each surgical procedure. Also included are comparisons of the training systems of gynecologic surgeons in Japan and the USA. Recently, minimally invasive surgeries such as laparoscopic and robotic approaches have been introduced into the gyn…
- Available Online
- View e-Book
- Other Authors
- Mikami, Mikio
- Responsibility
- Mikio Mikami, editor
- Place of Publication
- Singapore
- Publisher
- Springer
- Date of Publication
- 2019
- Physical Description
- 1 online resource (ix, 431 p.) : 22 illus., 19 illus. in color
- Series
- Comprehensive Gynecology and Obstetrics
- Series Title
- Comprehensive gynecology and obstetrics
- ISBN
- 9789811315190
- 9789811315183 (Print ed.)
- 9789811315206 (Print ed.)
- ISSN
- 2364-1932
- Specialty
- Gynecology
- Surgical Oncology
- Abstract
- This comprehensive volume provides exhaustive interpretations of surgery for gynecologic cancer. In these chapters, expert authors expound the history, principles and indications, preoperative evaluations, techniques, morbidity, and the future prospects for each surgical procedure. Also included are comparisons of the training systems of gynecologic surgeons in Japan and the USA. Recently, minimally invasive surgeries such as laparoscopic and robotic approaches have been introduced into the gynecologic oncology field. Readers will be interested to know the history, advances, and current status of gynecologic surgery in Japan. This collection methodically broadens understanding of new surgical methods with quality assurance aimed at saving the cancer patient’s life, from the point of view of gynecologic oncologists. Thus the book benefits not only experienced gynecologists, but also young physicians and all medical oncologists who are involved in gynecologic cancers.
- Contents
- 1.. Subspecialty Training of Gynecologic Surgery in Japan -- 2. Gynecologic Oncology Fellowship Training in the United States - 3. Surgical Anatomy of Gynecologic Malignancies - 4. Conization -- 5. Abdominal Hysterectomy -- 6. Modified Radical Hysterectomy -- 7. Abdominal Nerve-Sparing Radical Hysterectomy -- 8. Radical Vaginal Hysterectomy -- 9. Indication, Technique, and Outcome of Super-Radical Hysterectomy for Cervical Cancer -- 10. Laparoscopic Radical Hysterectomy -- 11. Robotic Surgery for Gynecologic Cancer -- 12. Radical Trachelectomy -- 13. Role of Para-aortic Lymphadenectomy During Radical Hysterectomy for Stage IB–IIB Cervical Cancer -- 14. Laparoscopic Pelvic Exenteration for Recurrent Cervical Cancer -- 15. Sentinel Node Navigation Surgery -- 16. Outline of Surgery (Refer to Hysterectomy in Section of Cervical Cancer) -- 17. Retroperitoneal Lymph Node Dissection -- 18. Laparoscopic Surgery for Endometrial Cancer -- 19. Sentinel Node Navigation Surgery for Endometrial Cancer -- 20. Outline of Surgical Treatments -- 21. Staging Laparotomy in Early Ovarian Cancer -- 22. Primary Debulking Surgery (Advanced) -- 23. Upper Abdomen -- 24. Lymph Node Dissection for Epithelial Ovarian Cancer -- 25. Intestinal Surgery -- 26. Interval Debulking Surgery -- 27. Fertility Preservation -- 28. Surgery for Vulvar Cancer and Vaginal Cancer.
- Format
- e-Book
- Location
- Online
Uterine Fibroids and Adenomyosis
https://libcat.nshealth.ca/en/permalink/provcat43080
Norihiro Sugino, editor.
--Singapore:
Springer
, c2018.
- Available Online
- View e-Book
- Location
- Online
This volume elucidates state-of-the-art findings of uterine fibroids and adenomyosis, incorporating expert basic knowledge. Uterine fibroids and adenomyosis are common uterine tumors in reproductive-age women. However, the pathogenesis of the tumors is still poorly understood, and both genetic and environmental factors may be involved in their generation or development. Recent research on the genomics and molecular biology of uterine fibroids and adenomyosis has facilitated a better understandi…
- Available Online
- View e-Book
- Other Authors
- Sugino, Norihiro
- Responsibility
- Norihiro Sugino, editor
- Place of Publication
- Singapore
- Publisher
- Springer
- Date of Publication
- c2018
- Physical Description
- 1 online resource (vii, 173 p.) : 40 illus., 29 illus. in color
- Series Title
- Comprehensive gynecology and obstetrics
- ISBN
- 9789811071676
- 9789811071669 (print ed.)
- 9789811071683 (print ed.)
- ISSN
- 2364-1932
- Subjects (MeSH)
- Leiomyoma
- Adenomyosis
- Specialty
- Gynecology
- Abstract
- This volume elucidates state-of-the-art findings of uterine fibroids and adenomyosis, incorporating expert basic knowledge. Uterine fibroids and adenomyosis are common uterine tumors in reproductive-age women. However, the pathogenesis of the tumors is still poorly understood, and both genetic and environmental factors may be involved in their generation or development. Recent research on the genomics and molecular biology of uterine fibroids and adenomyosis has facilitated a better understanding of the pathogenesis and pathophysiology of these benign tumors. Renowned experts provide detailed discussions of basic research and clinical aspects of uterine fibroids and adenomyosis in this book, from histopathology and molecular pathogenesis to diagnosis and the latest treatment of uterine fibroids, including pregnancy complications of adenomyosis. A great deal of information and a deep understanding of molecular and genetic biology have led to development of more innovative treatments of these tumors. Thus this book benefits not only oncologists, seasoned gynecologists, and obstetricians, but also molecular biologists and other basic researchers who are involved in the treatment of uterine fibroids.
- Contents
- 1. Histopathology of uterine fibroids -- 2. Genetics and genomics of uterine fibroids -- 3. Molecular pathogenesis of uterine fibroids -- 4. Stem cells and uterine fibroids -- 5. Epigenetics and uterine fibroids -- 6. Biomarkers of uterine fibroids -- 7. Current medical treatments for uterine fibroids -- 8. Diagnostic imaging for uterine fibroids, adenomyosis and uterine sarcomas -- 9. Pathogenesis of adenomyosis -- 10. Adenomyosis and subfertility -- 11. Surgical treatments for adenomyosis -- 12. Pregnancy complications of adenomyosis.
- Format
- e-Book
- Location
- Online
