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Allergy and Immunotoxicology in Occupational Health

https://libcat.nshealth.ca/en/permalink/provcat41941
Takemi Otsuki, Claudia Petrarca, Mario Di Gioacchino, editors. --Singapore: Springer , 2017.
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This book offers a collection of the latest clinical and research findings related to allergies, one of the most frequently treated conditions in occupational medicine. The chapters not only cover asthma but also elaborate on contact dermatitis, rhinitis, and other allergic conditions, providing readers with a comprehensive overview of the substances disrupting autoimmunity and their effects on the human body. Allergy and Immunotoxicology in Occupational Health is a valuable resource for profes…
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Other Authors
Otsuki, Takemi
Petrarca, Claudia
Di Gioacchino, Mario
Other Authors
International Congress of Occupational Health. Allergy and Immunotoxicology Scientific Committee
Responsibility
Takemi Otsuki, Claudia Petrarca, Mario Di Gioacchino, editors
Place of Publication
Singapore
Publisher
Springer
Date of Publication
2017
Physical Description
1 online resource (x, 152 pages) : 14 illus., 13 illus. in color
Series Title
Current Topics in Environmental Health and Preventive Medicine
ISBN
9789811003516
9789811003493 (print ed.)
ISSN
2364-8333
Subjects (MeSH)
Environmental Pollutants - toxicity
Multiple Chemical Sensitivity - immunology
Occupational Diseases - immunology
Occupational Health
Abstract
This book offers a collection of the latest clinical and research findings related to allergies, one of the most frequently treated conditions in occupational medicine. The chapters not only cover asthma but also elaborate on contact dermatitis, rhinitis, and other allergic conditions, providing readers with a comprehensive overview of the substances disrupting autoimmunity and their effects on the human body. Allergy and Immunotoxicology in Occupational Health is a valuable resource for professionals and researchers in the occupational health sector, who will discover novel insights into immune effects, providing a foundation for future considerations of the health impairments caused by environmental and occupational exposure to these substances.
Contents
1. Suppressive Effects of Asbestos Exposure on the Human Immune Surveillance System -- 2. Silica-Induced Immunotoxicity: Chronic and Aberrant Activation of Immune Cells -- 3. Engineered Nanomaterials and Occupational Allergy -- 4. Allergens in Occupational Allergy: Prevention and Management – Focus on Asthma -- 5. Particulate-Driven Type-2 Immunity and Allergic Responses -- 6. Traditional and Emerging Occupational Asthma in Japan -- 7. Skin Sensitization Model Based on Only Animal Data by Qualitative Structure-Toxicity Relationships (QSTR) Approach -- 8. Non-industrial Indoor Environments and Work-Related Asthma -- 9. Combined Effect on Immune and Nervous System of Aluminum Nanoparticles -- 10. Non Pulmonary Effects of Isocyanates -- 11. Skin Exposure to Nanoparticles and Possible Sensitization Risk.
Format
e-Book
Location
Online
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Allergy and Immunotoxicology in Occupational Health : The Next Step

https://libcat.nshealth.ca/en/permalink/provcat45288
Takemi Otsuki, Mario Di Gioacchino, Claudia Petrarca, editors. --Singapore: Springer , c2020.
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This book presents a collection of the latest clinical and research findings in the field of allergy and immunotoxicology, covering the allergic responses to various nanoparticles and nanomaterials, posttreatment immune reconstruction, and monitoring the workplace environment. Following on from its acclaimed predecessor, the book provides readers with novel insights into immune effects, autoimmune diseases, and theimmunotoxicity of various substances, such as silica and asbestos. Allergy and Im…
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Other Authors
Otsuki, Takemi
Di Gioacchino, Mario
Petrarca, Claudia
Responsibility
Takemi Otsuki, Mario Di Gioacchino, Claudia Petrarca, editors
Place of Publication
Singapore
Publisher
Springer
Date of Publication
c2020
Physical Description
1 online resource (x, 227 p.) : 18 illus., 15 illus. in color
Series Title
Current Topics in Environmental Health and Preventive Medicine
ISBN
9789811547355
9789811547348 (Print ed.)
9789811547362 (Print ed.)
9789811547379 (Print ed.)
ISSN
2364-8333
Subjects (MeSH)
Environmental Pollutants - toxicity
Multiple Chemical Sensitivity - immunology
Occupational Diseases - immunology
Occupational Health
Specialty
Allergy and Immunology
Occupational Health
Abstract
This book presents a collection of the latest clinical and research findings in the field of allergy and immunotoxicology, covering the allergic responses to various nanoparticles and nanomaterials, posttreatment immune reconstruction, and monitoring the workplace environment. Following on from its acclaimed predecessor, the book provides readers with novel insights into immune effects, autoimmune diseases, and theimmunotoxicity of various substances, such as silica and asbestos. Allergy and Immunotoxicology in Occupational Health - The Next Step invites readers in the occupational health sector to reflect on critical yet unresolved questions, and provides a foundation for future research on the health impairments resulting from environmental and occupational exposure to these substances.
Contents
1. Mechanisms of action of inhaled particulates on allergic lung inflammation -- 2. Metal nanoparticle health risk assessment -- 3. Immune toxicity of and allergic responses to nanomaterials -- 4. Inflammation and environmental (ultrafine) nanoparticles -- 5. Monitoring nanomaterials in the workplace -- 6. Immunotoxicicity of nanoparticles -- 7. Occupational respiratory allergic diseases: occupational asthma -- 8. Occupational respiratory allergic diseases: occupational rhinitis -- 9. Occupational skin diseases -- 10. Expanding concept of immune reconstitution inflammatory syndrome: a new view regarding how the immune system fights exogenous pathogens -- 11. Workplace risk assessment in occupational allergology -- 12. Pesticide and immunotoxicology -- 13. Clinical evaluation of plasma decoy receptor 3 levels in silicosis -- 14. Reduction of anti-tumor immunity caused by asbestos exposure.
Format
e-Book
Location
Online
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Bio-information for Hygiene

https://libcat.nshealth.ca/en/permalink/provcat46789
Hiroki Takada, Kiyoko Yokoyama. Springer , 2021.
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Responsibility
Hiroki Takada, Kiyoko Yokoyama
Publisher
Springer
Date of Publication
2021
Physical Description
1 online resource (viii, 161 pages) : illustrations
Series Title
Current Topics in Environmental Health and Preventive Medicine
ISBN
9789811521607
Specialty
Diagnosis
Format
e-Book
Location
Online
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Biological Effects of Fibrous and Particulate Substances

https://libcat.nshealth.ca/en/permalink/provcat40410
Takemi Otsuki, Yasuo Yoshioka, Andrij Holian, editors. (1st ed.) --Tokyo: Springer Japan , c2016.
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This volume examines our current understanding of the biological effects of fibrous and particulate substances, including discussions on nanoparticles. It offers comprehensive information on the latest insights into the immunological effects of various irritants on the human body. Readers will benefit from the contributing authors' diverse perspectives and extensive discussions of key issues, which include molecular alterations of the immune system and autoimmune diseases in connection with asb…
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Other Authors
Otsuki, Takemi
Yoshioka, Yasuo
Holian, Andrij
Responsibility
Takemi Otsuki, Yasuo Yoshioka, Andrij Holian, editors
Edition
1st ed.
Place of Publication
Tokyo
Publisher
Springer Japan
Date of Publication
c2016
Physical Description
1 online resource (x, 221 p. : 20 illus., 14 illus. in color)
Series Title
Current Topics in Environmental Health and Preventive Medicine
ISBN
9784431557326
9784431557319 (print ed.)
ISSN
2364-8333
Subjects (MeSH)
Air Pollutants - adverse effects
Environmental Exposure
Foreign-Body Reaction
Particulate Matter - adverse effects
Particulate Matter - immunology
Abstract
This volume examines our current understanding of the biological effects of fibrous and particulate substances, including discussions on nanoparticles. It offers comprehensive information on the latest insights into the immunological effects of various irritants on the human body. Readers will benefit from the contributing authors' diverse perspectives and extensive discussions of key issues, which include molecular alterations of the immune system and autoimmune diseases in connection with asbestos and silica, among others. The chapters also discuss recommendations, practical methods, and nanosafety science in situations involving exposure to nanotoxic substances. Edited in collaboration with the Japanese Society for Hygiene, this book provides up-to-date information on the immunological effects of nanotoxic substances to researchers interested in environmental and occupational health. Presenting a number of recent concepts and findings in the field, it enables readers to gain a comprehensive knowledge of health problems caused by environmental fibrous and particulate substances.
Contents
1. Macrophage and Multinucleated Giant Cell Classification -- 2. NLRP3 Inflammasome-Mediated Toxicity of Fibrous Particles -- 3. Approaching a Unified Theory for Particle-Induced Inflammation -- 4. Reproductive and Developmental Effects of Nanomaterials -- 5. Fibrogenic and Immunotoxic Responses to Carbon Nanotubes -- 6. Potential Hazards of Skin Exposure to Nanoparticles -- 7. Health Effects of Silver Nanoparticles and Silver Ions -- 8. Multiwalled Carbon Nanotube-Induced Pulmonary Fibrogenesis -- 9. Silicates and Autoimmunity -- 10. Asbestos Exposure and Autoimmunity -- 11. T Cell Alteration Caused by Exposure to Asbestos -- 12. Effects of Asbestos Fibers on Human Cytotoxic T Cells.
Format
e-Book
Location
Online
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Cadmium Toxicity : New Aspects in Human Disease, Rice Contamination, and Cytotoxicity

https://libcat.nshealth.ca/en/permalink/provcat44135
Seiichiro Himeno, Keiko Aoshima, editors. --Singapore: Springer , 2019.
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This volume focuses on cadmium (Cd) exposure, its effects on human health, the mechanism of Cd accumulation and the development of mitigation technologies. Further, it discusses clinical, epidemiological, agricultural, toxicological, and biochemical aspects of Cd pollution and presents recent biochemical studies on molecular mechanisms of Cd cytotoxicity and cellular transport as well as the mechanism of Cd-induced disturbances in phosphorus (P) metabolism. It also provides insights into the pa…
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Other Authors
Himeno, Seiichiro
Aoshima, Keiko
Responsibility
Seiichiro Himeno, Keiko Aoshima, editors
Place of Publication
Singapore
Publisher
Springer
Date of Publication
2019
Physical Description
1 online resource (viii, 190 p.) : 68 illus., 51 illus. in color
Series
Current Topics in Environmental Health and Preventive Medicine
Series Title
Current Topics in Environmental Health and Preventive Medicine
ISBN
9789811336300
9789811336294 (Print ed.)
9789811336317 (Print ed.)
ISSN
2364-8333
Subjects (MeSH)
Cadmium - toxicity
Cadmium Poisoning
Environmental Exposure
Food Contamination - prevention & control
Specialty
Toxicology
Abstract
This volume focuses on cadmium (Cd) exposure, its effects on human health, the mechanism of Cd accumulation and the development of mitigation technologies. Further, it discusses clinical, epidemiological, agricultural, toxicological, and biochemical aspects of Cd pollution and presents recent biochemical studies on molecular mechanisms of Cd cytotoxicity and cellular transport as well as the mechanism of Cd-induced disturbances in phosphorus (P) metabolism. It also provides insights into the pathophysiology of itai-itai disease, a serious condition caused by Cd pollution. Cadmium: New Aspects in Human Disease, Rice Contamination, and Cytotoxicity is a valuable resource for scientists involved in heavy metal toxicology, botanical sciences, and regulatory sciences. Addressing the features of Cd pollution in the past and in the present, as well as future perspectives, this is a must-have book for students, researchers and practitioners interested in global and local metal pollution.
Contents
Part I. Overview -- 1. Historical Lessons on Cadmium Environmental Pollution Problems in Japan and Current Cadmium Exposure Situation -- Part II. Health Effects of Cadmium in Human Populations and its Relation to Cadmium Exposure Levels -- 2. Recent Clinical and Epidemiological Studies of Itai-Itai Disease (Cadmium-Induced Renal Tubular Osteomalacia) and Cadmium Nephropathy in the Jinzu River Basin in Toyama Prefecture, Japan -- 3. Novel Pathological Study of Cadmium Nephropathy of Itai-itai Disease -- 4. Long-Term Follow-Up Study of Residents Exposed to Cadmium in Kakehashi River Basin, Ishikawa, Japan -- 5. Effects of Cadmium Exposure on Life Prognosis -- 6. Cadmium Exposure and Its Effects on the Health Status of Rice Farmers in Akita Prefecture 7. Dietary Cadmium Intake Among General Populations in Japan and East Asia -- Part III. Rice Contamination by Cadmium and its Remediation -- 8. Regulations for Cadmium in Rice and Soil in Japan and Countermeasures to Reduce the Concentrations -- 9. Molecular Mechanism of Cadmium Accumulation in Rice - 10. Mitigation Strategies for Cadmium and Arsenic in Rice -- 11. Development of Low-Cadmium-Accumulating Rice -- Part IV. New Aspects in the Mechanisms of Cadmium Toxicity -- 12. Novel Mechanisms of Cadmium-Induced Toxicity in Renal Cells - 13. Roles of Metal Transporters in Cellular Cadmium Transport in Mammals -- 14. Disturbance in Phosphorus Metabolism by Cadmium Exposure.
Format
e-Book
Location
Online
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Health Impacts of Developmental Exposure to Environmental Chemicals

https://libcat.nshealth.ca/en/permalink/provcat44872
Reiko Kishi, Philippe Grandjean, editors. --Singapore: Springer , c2020.
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This book provides concise and cutting-edge studies on threats resulting from exposure to environmental chemicals that can affect human health and development, with a particular emphasis on the DOHaD concept. The book is divided into five main parts, the first of which includes an introduction to the impacts of developmental exposure to environmental chemicals and historical perspectives, while the second focuses on how environmental chemicals can affect human organs, including neurodevelopment…
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Other Authors
Kishi, Reiko
Grandjean, Philippe
Responsibility
Reiko Kishi, Philippe Grandjean, editors
Place of Publication
Singapore
Publisher
Springer
Date of Publication
c2020
Physical Description
1 online resource (xi, 557 p.) : 50 illus., 23 illus. in color
Series Title
Current Topics in Environmental Health and Preventive Medicine
ISBN
9789811505201
9789811505195 (Print ed.)
9789811505218 (Print ed.)
9789811505225 (Print ed.)
ISSN
2364-8333
Subjects (MeSH)
Environmental Exposure - adverse effects
Environmental Health
Environmental Pollutants - toxicity
Prenatal Exposure Delayed Effects
Specialty
Environmental Health
Toxicology
Abstract
This book provides concise and cutting-edge studies on threats resulting from exposure to environmental chemicals that can affect human health and development, with a particular emphasis on the DOHaD concept. The book is divided into five main parts, the first of which includes an introduction to the impacts of developmental exposure to environmental chemicals and historical perspectives, while the second focuses on how environmental chemicals can affect human organs, including neurodevelopment, immune functions, etc. In turn, the third part addresses the characteristics of specific chemicals and their effects on human health and development, while the fourth part provides a basis for future studies by highlighting the latest innovations in toxicology, remaining challenges, and promising strategies in children’s environmental health research, as well as ideas on how to bridge the gap between research evidence and practical policymaking. The fifth and last part outlines further research directions and related policymaking aspects. Health Impacts of Developmental Exposure to Environmental Chemicals will appeal to young and veteran researchers, students, and physicians (especially gynecologists and pediatricians) who are seeking comprehensive information on how children’s health can be affected by harmful chemicals and other environmental toxicants.
Contents
Part I. Introduction -- 1. Impacts of Developmental Exposure to Environmental Chemicals on Human Health with Global Perspectives -- Part II. Adverse Health Effects on Human Developing Organs Caused by Environmental Chemicals: the Role That Chemicals Might Play -- 2. Environmental Exposures and Adverse Pregnancy-Related Outcomes -- 3. Effects of Environmental Chemical Exposure on Birth Defects (Except Cryptorchidism and Hypospadias) -- 4. Cryptorchidism and Hypospadias -- 5. Endocrine-Distributing Chemicals and Reproductive Function -- 6. Thyroid Hormone System and Development -- 7. Neurodevelopment and Neurobehavioral Disorders in Relation to Developmental Exposures -- 8. Immunotoxicity: Impacts and Research Approaches -- 9. Long-Term Implications of Developmental Programming and Obesity -- Part III. Impact of Environmental Chemical Hazards on Human Development -- 10. Impact of Air Pollution Hazards on Human Development -- 11. Mercury, Lead, Manganese, and Hazardous Metals -- 12. Environmental Pollution and Recent Data on Asian Children’s Health in Relation to Pre- and Early Post-natal Exposure to Persistent Organic Pollutants, Including PCBs, PCDD/PCDFs, and Organochlorine Pesticides -- 13. Effects of Developmental Exposure to Perfluoroalkyl Substances on Health Outcomes in Pregnant Women and Offspring -- 14. Brominated Flame Retardants (BFRs) -- 15. Phthalates -- 16. Bisphenols and Alkylphenols -- Part IV. Important Aspects of Research for Prevention and Strategy -- 17. Adverse Outcome Pathways for Developmental Toxicity -- 18. Exposomics: The Exposome in Early Life -- 19. Gene–Environment Interactions to Detect Adverse Health Effects on the Next Generation -- 20. Epigenetics: Strategies for Prevention Research -- 21. From Research to Intervention -- Part V. Closing -- 22. Further Direction of Research and Policy Making of Environment and Children’s Health.
Format
e-Book
Location
Online
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Indoor Environmental Quality and Health Risk toward Healthier Environment for All

https://libcat.nshealth.ca/en/permalink/provcat44855
Reiko Kishi, Dan Norbäck, Atsuko Araki, editors. --Singapore: Springer , c2020.
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This volume discusses the effects of indoor air environment and pollution in modern buildings on human health. Highlighting epidemiological studies and the determining factors, it offers proposals for improving indoor air quality (IAQ) in different environments. Focusing not only on homes and offices, but also vehicles and aircrafts, it details practical methods of measuring and assessing indoor air quality. Written by pioneering researchers, Indoor Environmental Quality and Health Risk toward …
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Other Authors
Kishi, Reiko
Norbäck, Dan
Araki, Atsuko
Responsibility
Reiko Kishi, Dan Norbäck, Atsuko Araki, editors
Place of Publication
Singapore
Publisher
Springer
Date of Publication
c2020
Physical Description
1 online resource (viii, 333 p.) : 75 illus., 50 illus. in color
Series Title
Current Topics in Environmental Health and Preventive Medicine
ISBN
9789813291829
9789813291812 (Print ed.)
9789813291836 (Print ed.)
9789813291843 (Print ed.)
ISSN
2364-8333
Subjects (MeSH)
Air Pollutants
Air Pollution, Indoor
Environmental Exposure
Environmental Health
Preventive Medicine
Quality Improvement
Specialty
Environmental Health
Abstract
This volume discusses the effects of indoor air environment and pollution in modern buildings on human health. Highlighting epidemiological studies and the determining factors, it offers proposals for improving indoor air quality (IAQ) in different environments. Focusing not only on homes and offices, but also vehicles and aircrafts, it details practical methods of measuring and assessing indoor air quality. Written by pioneering researchers, Indoor Environmental Quality and Health Risk toward Healthier Environment for All is a valuable resource for both new and established researchers as well as students seeking a comprehensive overview of the facts on indoor air quality and health. Also is also of interest to hygiene experts in industry, occupational health and safety professionals, governmental public health sectors and school physicians.
Contents
Part I. Introduction -- 1. Importance of Indoor Environmental Quality on Human Health toward Achievement of the SDGs -- Part II. Epidemiological Studies on Indoor Air Quality and Health -- 2. Sick Building/House Syndrome -- 3. Associations with Home Environment for Asthma, Rhinitis and Dermatitis -- 4. Offices -- 5. The Indoor Environment in Schools, Kindergartens and Day Care Centres -- 6. In-Vehicle Exposures at Transportation and the Health Concerns -- Part III. Factors Determining Indoor Air Qualities and Their Health Impacts -- 7. Aldehydes, Volatile Organic Compounds (VOCs), and Health -- 8. Semi-Volatile Organic Compounds (SVOCs): Phthalates and Phosphorous Frame Retardants and Health Risks -- 9. Microbial Agents in the Indoor Environment: Associations with Health -- 10. Dampness, Indoor Mould and Health -- 11. Particles Matter, Nitrogen Dioxide and Sulfur Dioxide -- 12. Combustion and Cookstoves -- 13. Indoor Thermal Environment and Cardiovascular Diseases -- Part IV. Provision for Improving Indoor Environment Quality and Health -- 14. Housing Performance and Equipment for Healthy Indoor Environment -- 15. Sick Building Syndrome (SBS), Personality, Psychosocial Factors and Treatment -- 16. Guidelines and Regulations for Indoor Environmental Quality -- Part V. Conclusion -- 17. Future Directions of Research on Indoor Environment, Indoor Air Quality (IAQ), and Health.
Format
e-Book
Location
Online
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Moyamoya Disease Explored Through RNF213 : Genetics, Molecular Pathology, and Clinical Sciences

https://libcat.nshealth.ca/en/permalink/provcat41964
Akio Koizumi, Kazuhiro Nagata, Kiyohiro Houkin, Teiji Tominaga, Susumu Miyamoto, Shigeo Kure, Elizabeth Tournier-Lasserve, editors. --Singapore: Springer , 2017.
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This book presents the latest findings on biological, epidemiological, and clinical investigations of RNF213, which is thought to be involved in many biological processes and plays a key role in cerebro- and cardiovascular disease . By discussing the epidemiology and genetic epidemiology of the disease with a particular focus on the molecular function of RNF213, research using animal models, diagnosis, therapy and clinical management around the world, this work makes a valuable contribution to …
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Other Authors
Koizumi, Akio
Nagata, Kazuhiro
Houkin, Kiyohiro
Tominaga, Teiji
Miyamoto, Susumu
Kure, Shigeo
Tournier-Lasserve, Elizabeth
Responsibility
Akio Koizumi, Kazuhiro Nagata, Kiyohiro Houkin, Teiji Tominaga, Susumu Miyamoto, Shigeo Kure, Elizabeth Tournier-Lasserve, editors
Place of Publication
Singapore
Publisher
Springer
Date of Publication
2017
Physical Description
1 online resource (viii, 185 pages) : 36 illus., 22 illus. in color
Series Title
Current Topics in Environmental Health and Preventive Medicine
ISBN
9789811027116
9789811027109 (print ed.)
ISSN
2364-8333
Subjects (MeSH)
Adenosine Triphosphatases - genetics
Genetic Predisposition to Disease
Moyamoya Disease - genetics
Moyamoya Disease - physiopathology
Ubiquitin-Protein Ligases - genetics
Abstract
This book presents the latest findings on biological, epidemiological, and clinical investigations of RNF213, which is thought to be involved in many biological processes and plays a key role in cerebro- and cardiovascular disease . By discussing the epidemiology and genetic epidemiology of the disease with a particular focus on the molecular function of RNF213, research using animal models, diagnosis, therapy and clinical management around the world, this work makes a valuable contribution to the study of the disease. Moyamoya Disease Explored Through RNF213 is an indispensable resource for both beginning and experienced researchers, pediatricians, neurologists, and neurosurgeons who are seeking comprehensive information on adult and childhood stroke.
Contents
Part I: Prologue -- 1. A prologue to moyamoya disease and RNF213 -- 2. Concept of moyamoya Disease -- Part II: Genetic Epidemiology -- 3. Molecular Epidemiology in East Asian Countries and in the World -- Part III: Biochemistry, Function and Molecular Pathology -- 4. Molecular Biology of Mysterin/RNF213 -- 5. Physiological Role of Mysterin/RNF213 in Zebrafish -- 6. Pathological Investigation on RNF213: Animal Models Knockout and Transgenic Mice in Diabetes and Signal Transduction -- 7. Pathological Investigation on RNF213: Animal Models of Rnf213-knockout and Knock-in Mice -- 8. RNF213 and Circulating Factors in Patients with Moyamoya Disease -- 9. Genetics of Moyamoya beyond RNF213. Monogenic Moyamoya Syndromes -- Part IV: Clinical Management 10. Natural History and Long-term Clinical Outcome after Conservative and Surgical Management -- 11. Significance of RNF213 in Clinical Management in Japan -- 12. Significance of RNF213 in Clinical Management in China -- 13. The Different Forms of Moyamoya Disease and Their Clinical Management -- 14. Vascular Diseases Attributable to RNF213 Other than Moyamoya Disease -- Part V: Epilogue -- 15. Future Clinical Perspectives on RNF213 in Moyamoya Disease.
Format
e-Book
Location
Online
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8 records – page 1 of 1.