Antimicrobial Resistance in the 21st Century
https://libcat.nshealth.ca/en/permalink/provcat42795
I.W. Fong, David Shlaes, Karl Drlica, editors.
(Second edition)
--Cham:
Springer
, c2018.
- Available Online
- View e-Book
- Location
- Online
Antimicrobial resistance is now a general problem. Many of us have elderly relatives who died from a drug-resistant infection, and some of us have suffered from a resistant urinary infection that likely came from intestinal bacteria following antibiotic consumption. Antimicrobial Resistance in the 21st Century provides a broad introduction to the subject in which the situation with problematic pathogens is detailed, the biology of resistance is described, and gaining approval for new antibiotic…
- Available Online
- View e-Book
- Other Authors
- Fong, I.W. (Ignatius W.)
- Shlaes, David
- Drlica, Karl
- Responsibility
- I.W. Fong, David Shlaes, Karl Drlica, editors
- Edition
- Second edition
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2018
- Physical Description
- 1 online resource (xviii, 775 p.) : 106 illus., 74 illus. in color
- Series Title
- Emerging infectious diseases of the 21st century
- ISBN
- 9783319785387
- 9783319785370 (print ed.)
- 9783319785394 (print ed.)
- Subjects (MeSH)
- Communicable Diseases - epidemiology
- Communicable Diseases, Emerging
- Drug Resistance, Microbial
- Specialty
- Infectious Disease Medicine
- Pharmacology
- Abstract
- Antimicrobial resistance is now a general problem. Many of us have elderly relatives who died from a drug-resistant infection, and some of us have suffered from a resistant urinary infection that likely came from intestinal bacteria following antibiotic consumption. Antimicrobial Resistance in the 21st Century provides a broad introduction to the subject in which the situation with problematic pathogens is detailed, the biology of resistance is described, and gaining approval for new antibiotics is discussed. Some topics are immediately practical, such as watching for resistant pathogen sub-populations in cultures taken from patients; other topics point to future research efforts that may lead to new antimicrobials and ways to stimulate the action of existing ones. Overall, Antimicrobial Resistance in the 21st Century provides an update for physicians, serves as a starting point for graduate students interested in solving the resistance problem, and may serve as a text for a course on resistance. Lay readers familiar with microbiology will gain an appreciation for a medical issue that promises to be one of the most important of our time.
- Contents
- 1. Introduction: Coordinated Global Action is Needed to Combat Antimicrobial Resistance -- Part I: Examples of Resistance -- 2. Antimicrobial Resistance Among Streptococcus pneumoniae -- 3. Emergence of MRSA in the Community -- 4. Resistance of Gram-negative Bacilli to Antimicrobials -- 5. Drug Resistance in Tuberculosis -- 6. Anaerobic Bacteria: Antimicrobial Susceptibility Testing and Resistance Patterns -- 7. Clinical Significance and Biologic Basis of HIV Drug Resistance -- 8. Resistance of Herpesviruses to Antiviral Agents -- 9. Heteroresistance: A Harbinger of Future Resistance -- Part II: Biology of Resistance -- 10. Epidemiology of Bacterial Resistance -- 11. Transmissible Antibiotic Resistance -- 12. Antibiotics and Resistance in the Environment -- 13. Phenotypic Tolerance and Bacterial Persistence -- 14. Staphylococcus aureus Adaptation During Infection -- 15. Bacterial Signal Transduction Systems in Antimicrobial Resistance -- 16. Fluoroquinolone Interactions with Bacterial Type II Topoisomerases and Target-mediated Drug Resistance -- Part III: Finding New Antimicrobials -- 17. Natural Products in Antibiotic Discovery -- 18. The New vs. Old Target Debate For Drug Discovery -- 19. Non-quinolone Topoisomerase Inhibitors -- 20. Antimicrobial-Mediated Bacterial Suicide -- 21. PK/PD-based Prediction of "Anti-mutant" Antibiotic Exposures Using In Vitro Dynamic Models -- Part IV: Bringing Compounds to Market -- 22. The Role of Pharmacometrics in the Development of Antimicrobial Agents -- 23. New Regulatory Pathways for Antibacterial Drugs -- 24. Economic Incentives for Antibacterial Drug Development: Alternative Market Structures to Promote Innovation.
- Format
- e-Book
- Location
- Online
Bioterrorism and Infectious Agents : A New Dilemma for the 21st Century
https://libcat.nshealth.ca/en/permalink/provcat29166
edited by I. W. Fong, Kenneth Alibek.
--New York, NY:
Springer-Verlag
, c2009.
- Available Online
- View e-Book
- Location
- Online
- Available Online
- View e-Book
- Other Authors
- Fong, Ignatius W.
- Alibek, Kenneth
- Responsibility
- edited by I. W. Fong, Kenneth Alibek
- Place of Publication
- New York, NY
- Publisher
- Springer-Verlag
- Date of Publication
- c2009
- Physical Description
- 1 online resource (xvi, 271 p.)
- Series Title
- Emerging infectious diseases of the 21st century
- ISBN
- 9781441912664
- 9781441912657 (print)
- Subjects (MeSH)
- Bioterrorism - prevention & control
- Subjects (LCSH)
- Public health
- Infectious diseases
- Contents
- 1. Anthrax: A Disease and a Weapon -- 2. Plague as a Biological Weapon -- 3. Tularemia and Bioterrorism -- 4. Melioidosis and Glanders as Possible Biological Weapons -- 5. Smallpox as a Weapon for Bioterrorism -- 6. Hemorrhagic Fever Viruses as Biological Weapons -- 7. Botulism as a Potential Agent of Bioterrorism -- 8. Ricin: A Possible, Noninfectious Biological Weapon -- 9. Bioterrorism Alert for Health Care Workers -- 10. The Economics of Planning and Preparing for Bioterrorism.
- Format
- e-Book
- Location
- Online
Challenges in infectious diseases
https://libcat.nshealth.ca/en/permalink/provcat32392
I.W. Fong, editor.
--New York, NY:
Springer
, c2013.
- Available Online
- View e-Book
- Location
- Online
This latest volume in the Emerging Infectious Diseases of the 21st Century series provides timely information and discussions on future approaches to controlling various infectious disease worldwide. Challenges in Infectious Diseases addresses numerous advances in medical-scientific knowledge, medical technology and biological and diagnostic techniques over the past decade. However recent developments have provided less dramatic changes or improvements in management of medical conditions. This …
- Available Online
- View e-Book
- Other Authors
- Fong, I.W. (Ignatius W.)
- Responsibility
- I.W. Fong, editor
- Place of Publication
- New York, NY
- Publisher
- Springer
- Date of Publication
- c2013
- Physical Description
- 1 online resource (xii, 319 p.)
- Series Title
- Emerging infectious diseases of the 21st century
- ISBN
- 9781461444961
- Subjects (MeSH)
- HIV infections
- Parasitic Diseases
- Tuberculosis, Multidrug-Resistant
- Subjects (LCSH)
- Immunology
- Monoclonal antibodies
- Drug interactions
- Abstract
- This latest volume in the Emerging Infectious Diseases of the 21st Century series provides timely information and discussions on future approaches to controlling various infectious disease worldwide. Challenges in Infectious Diseases addresses numerous advances in medical-scientific knowledge, medical technology and biological and diagnostic techniques over the past decade. However recent developments have provided less dramatic changes or improvements in management of medical conditions. This volume will address some of the emerging issues, challenges, and controversies of infectious diseases facing the global community today.
- Contents
- Preface -- HIV Epidemic -- Multidrug-resistant Bacteria: The Emerging Crisis -- Multidrug-Resistant Tuberculosis: A Global Challenge -- Urbanization and Infectious Diseases: General Principles, Historical Perspectives, and Contemporary Challenges -- Challenges in enteric epidemics from Cholera to malnutrition and cognitive development: barometers of inadequate water sanitation -- Challenges in control and eradication of malaria -- Lymphatic filariasis: progress and challenges in the move toward elimination -- Leishmaniasis: Challenges in the control and eradication -- Challenges in controlling and eliminating Schistosomiasis -- Dengue Infections -- Index.
- Format
- e-Book
- Location
- Online
Current Trends and Concerns in Infectious Diseases
https://libcat.nshealth.ca/en/permalink/provcat45294
I. W. Fong.
--Cham:
Springer
, c2020.
- Available Online
- View e-Book
- Location
- Online
A follow-up to Emerging Issues and Controversies in Infectious Diseases, this volume provides a comprehensive review of topical issues in infectious diseases, highlighting the controversies related to the newest findings and recommendations. Coverage includes trends and debates in HIV research, community-acquired pneumonia, H. pylori, progress in Hepatitis C treatment paired with the lack of progress on Hepatitis B, and the effects of climate change on infectious disease epidemiology, among oth…
- Available Online
- View e-Book
- Author
- Fong, I.W. (Ignatius W.)
- Responsibility
- I. W. Fong.
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2020
- Physical Description
- 1 online resource (xix, 329 p.) : 5 illus.
- Series Title
- Emerging infectious diseases of the 21st century
- ISBN
- 9783030369668
- 9783030369651 (Print ed.)
- 9783030369675 (Print ed.)
- 9783030369682 (Print ed.)
- Subjects (MeSH)
- Communicable Disease Control
- Communicable Diseases
- Specialty
- Infectious Disease Medicine
- Abstract
- A follow-up to Emerging Issues and Controversies in Infectious Diseases, this volume provides a comprehensive review of topical issues in infectious diseases, highlighting the controversies related to the newest findings and recommendations. Coverage includes trends and debates in HIV research, community-acquired pneumonia, H. pylori, progress in Hepatitis C treatment paired with the lack of progress on Hepatitis B, and the effects of climate change on infectious disease epidemiology, among others. This is an essential resource for practicing and academic physicians, investigators, residents, and fellows focused on infectious diseases, infection control, public health, and global health.
- Contents
- 1. Prevention of HIV Infection -- 2. Immune Reconstitution Inflammatory Syndrome and Paradoxical Reaction -- 3. Issues in Community-acquired Pneumonia -- 4. Helicobacter pylori Infection: When Should It be Treated? -- 5. Major Advances in Hepatitis C Treatment, but not Hepatitis B -- 6. Infectious Complications of Biologic Agents -- 7. Climate Change: Impact on Health and Infectious Diseases Globally -- 8. Blood Transfusion-associated Infections in the 21st Century: New Challenges -- 9. Mass Drug Treatment of Tropical Diseases: Is It Really Progress? -- 10. Issues in Therapeutics of Some Bacterial Infections -- 11. Issues and Concerns in the Management of Systemic Candidiasis -- 12. Emerging and Difficult-to-Treat Nontuberculous Mycobacteria Infections.
- Format
- e-Book
- Location
- Online
Emerging Issues and Controversies in Infectious Disease
https://libcat.nshealth.ca/en/permalink/provcat29672
edited by I. W. Fong.
--New York, NY:
Springer-Verlag
, c2009.
- Available Online
- View e-Book
- Location
- Online
- Available Online
- View e-Book
- Author
- Fong, I.W. (Ignatius W.)
- Responsibility
- edited by I. W. Fong
- Place of Publication
- New York, NY
- Publisher
- Springer-Verlag
- Date of Publication
- c2009
- Series Title
- Emerging infectious diseases of the 21st century
- ISBN
- 9780387848419
- Subjects (MeSH)
- Communicable Disease Control
- Communicable Diseases
- Subjects (LCSH)
- Infectious diseases
- Format
- e-Book
- Location
- Online
Emerging Zoonoses : A Worldwide Perspective
https://libcat.nshealth.ca/en/permalink/provcat41657
I.W. Fong.
--Cham:
Springer
, 2017.
- Available Online
- View e-Book
- Location
- Online
The book begins with a review of zoonotic pandemics of the past: the "Black Death" or bubonic plague of the Middle Ages, the Spanish Influenza pandemic (derived from avian influenza) of the early 20th century, to the more modern pandemic of AIDS/HIV infection, which originated in Africa from primates. However, the majority of chapters focus on more recent zoonoses, which have been recognized since the late 20th century to the present: SARS and MERS coronaviruses New avian influenza viruses The …
- Available Online
- View e-Book
- Author
- Fong, I.W. (Ignatius W.)
- Responsibility
- I.W. Fong
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- 2017
- Physical Description
- 1 online resource (xv, 250 pages) : 10 illus., 9 illus. in color
- Series Title
- Emerging infectious diseases of the 21st century
- ISBN
- 9783319508900
- 9783319508887 (print ed.)
- Subjects (MeSH)
- Communicable Diseases, Emerging
- Global Health
- Zoonoses
- Abstract
- The book begins with a review of zoonotic pandemics of the past: the "Black Death" or bubonic plague of the Middle Ages, the Spanish Influenza pandemic (derived from avian influenza) of the early 20th century, to the more modern pandemic of AIDS/HIV infection, which originated in Africa from primates. However, the majority of chapters focus on more recent zoonoses, which have been recognized since the late 20th century to the present: SARS and MERS coronaviruses New avian influenza viruses The tick-borne Henan fever virus from China The tick-borne Heartland virus from the United States Recently recognized bacterial pathogens, such as Streptococcus suis from pigs. In addition, reemergence of established zoonoses that have expanded their niche are reviewed, such as the spread of Zika virus and Chikungunya virus to the Western Hemisphere, and the emergence and spread of Ebola virus infection in Africa. A chapter is also devoted to an overview of the mechanisms and various types of animals involved in the transmission of diseases to humans, and the potential means of control and prevention. Many endemic and sporadic diseases are still transmitted by animals, through either direct or indirect contact, and zoonoses are estimated to account for about 75% of all new and emerging infectious diseases. It is predicted by public health experts that the next major pandemic of infectious disease will be of animal origin, making Emerging Zoonoses: A Worldwide Perspective a crucial resource to all health care specialists by providing them with much needed information on these zoonotic diseases.
- Contents
- 1. Pandemic zoonoses from the Middle-Ages to the 20th Century -- 2. Animals and mechanisms of disease transmission -- 3. Swine and avian influenza outbreaks in recent times -- 4. Emerging animal coronaviruses: first SARS and now MERS -- 5. Emergence of new tickborne infections -- 6. Chikungunya virus and Zika virus expansion: an imitation of Dengue virus -- 7. Ebola and Marburg: out of Africa -- 8. Hepatitis E: a zoonosis -- 9. Zoonotic malaria: plasmodium knowlesi -- 10. Zoonotic streptococci: a focus on Streptocccus suis -- 11. New and emerging parasitic zoonoses.
- Format
- e-Book
- Location
- Online
Medico-Legal Issues in Infectious Diseases : Guide For Physicians
https://libcat.nshealth.ca/en/permalink/provcat29363
by I.W. Fong.
--New York, NY:
Springer Science+Business Media
, c2011.
- Available Online
- View e-Book
- Location
- Online
- Available Online
- View e-Book
- Author
- Fong, I.W. (Ignatius W.)
- Responsibility
- by I.W. Fong
- Place of Publication
- New York, NY
- Publisher
- Springer Science+Business Media
- Date of Publication
- c2011
- Series Title
- Emerging infectious diseases of the 21st century
- ISBN
- 9781441980533
- Subjects (MeSH)
- Communicable Disease Control - legislation & jurisprudence
- Subjects (LCSH)
- Infectious diseases
- Public health
- Law
- Format
- e-Book
- Location
- Online
The role of microbes in common non-infectious diseases
https://libcat.nshealth.ca/en/permalink/provcat33366
I.W. Fong.
--New York, NY:
Springer
, c2014.
- Available Online
- View e-Book
- Location
- Online
This new volume in the series Emerging Infectious Diseases of the 21st Century is a novel book on the role of microbes in the pathogenesis of common and disabling non-infectious diseases. New insights have emerged over the past several years suggesting that our commensal microflora of the gut is extremely important in regulating physiological and immune functions of the body. Covered are the perturbations of the normal composition of our endogenous microbiota, influenced by diet and genetic pre…
- Available Online
- View e-Book
- Author
- Fong, I.W. (Ignatius W.)
- Responsibility
- I.W. Fong
- Place of Publication
- New York, NY
- Publisher
- Springer
- Date of Publication
- c2014
- Physical Description
- 1 online resource (xiv, 185 pages)
- Series Title
- Emerging infectious diseases of the 21st century
- ISBN
- 9781493916702 (electronic bk.)
- 9781493916696
- Subjects (MeSH)
- Disease - etiology
- Microbiological Phenomena
- Subjects (LCSH)
- Biomedicine
- Infectious Diseases
- Immunology
- Microbiology
- Abstract
- This new volume in the series Emerging Infectious Diseases of the 21st Century is a novel book on the role of microbes in the pathogenesis of common and disabling non-infectious diseases. New insights have emerged over the past several years suggesting that our commensal microflora of the gut is extremely important in regulating physiological and immune functions of the body. Covered are the perturbations of the normal composition of our endogenous microbiota, influenced by diet and genetic predispositions, as well as the mechanisms to produce common disorders such as obesity, diabetes, irritable bowel syndrome, colon cancer, and atherosclerotic vascular diseases. Also explored is the evidence suggesting that predisposition to increasingly common afflictions such as asthma and multiple sclerosis is influenced, in combination with our genetic composition, by early life exposure to environmental microbes and the time of onset of common viral infections. Chapters provide the most recent information on these disorders with regards to epidemiology, current concepts on pathogenesis and mechanisms of their biology, recent research and data on the role of microbes, analysis of their validity, and conclusive remarks and areas for future research. The Role of Microbes in Common Non-Infectious Diseases is an excellent resource for both physicians and investigators from a broad range of disciplines that will help to stimulate new concepts of disease pathogenesis, and lead to the unraveling of their mechanisms of diseases and to novel treatments. About the Author Ignatius [Bill] Fong is a Professor of Medicine at the University of Toronto and he is an author/ editor of 8 previously published books on Infectious Diseases. His research interests include topics in clinical infectious disease, HIV infection, and microbial-induced or -associated atherosclerosis.
- Contents
- Irritable Bowel Syndrome and Microbial Pathogenesis -- Microbes in Colon Cancer and Inflammatory Bowel Disease -- The Role of Microbes in Obesity -- Microbes in the Pathogenesis of Diabetes Mellitus -- Asthma and Microbes: a New Paradigm -- Chronic Fatigue Syndrome: Searching for a Microbial Etiology -- Can Microbes Play a Role in the Pathogenesis of Alzheimer Disease?- Multiple Sclerosis and Microbes -- The Role of Infections and Microbes in Atherosclerosis.
- Format
- e-Book
- Location
- Online
