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Acute Kidney Injury and Regenerative Medicine

https://libcat.nshealth.ca/en/permalink/provcat45511
Yoshio Terada, Takashi Wada, Kent Doi, editors. --Singapore: Springer , c2020.
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This book presents up-to-date information on the clinical-pathophysiological features of acute renal injury and discusses the KDIGO diagnostic criteria, as well as novel experimental findings, including in the area of regenerative medicine. It also highlights the clinical-pathophysiological importance of AKI in clinical settings, including differential diagnoses and management of AKI. In the past, the pathology associated with sudden renal impairment was characterized as acute renal failure (AR…
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Other Authors
Terada, Yoshio
Wada, Takashi
Doi, Kent
Responsibility
Yoshio Terada, Takashi Wada, Kent Doi, editors
Place of Publication
Singapore
Publisher
Springer
Date of Publication
c2020
Physical Description
1 online resource (ix, 396 p.) : 39 illus., 33 illus. in color
ISBN
9789811511080
9789811511073 (Print ed.)
9789811511097 (Print ed.)
9789811511103 (Print ed.)
Subjects (MeSH)
Acute Kidney Injury - etiology
Acute Kidney Injury - therapy
Regenerative Medicine - methods
Specialty
Nephrology
Regenerative Medicine
Abstract
This book presents up-to-date information on the clinical-pathophysiological features of acute renal injury and discusses the KDIGO diagnostic criteria, as well as novel experimental findings, including in the area of regenerative medicine. It also highlights the clinical-pathophysiological importance of AKI in clinical settings, including differential diagnoses and management of AKI. In the past, the pathology associated with sudden renal impairment was characterized as acute renal failure (ARF). However, in the 2000s, the joint efforts of specialists in fields including nephrology, intensive care medicine, and cardiovascular medicine led to the introduction of a novel concept known as acute kidney injury (AKI). As medical care progressed, patients such as high-risk elderly subjects who were not deemed to be candidates for invasive therapy came to be treated in intensive care units (ICUs). As a result, kidney injury as a subset of multiple organ failure was re-considered as AKI, especially in intensive care medicine. AKI was then proposed as a novel disease concept to emphasize the importance of early diagnosis and early intervention to improve prognosis. Presenting novel features, such as the definition of AKI, risk factors and management; biomarkers, such as neutrophil gelatinase-associated lipocalin (NGAL) and L-type fatty acid-binding protein (L-FABP); long-term outcomes of AKI; as well as renal regeneration using iPS cell, manipulation of embryonic genes, and Xenotransplanted embryonic kidney, this book is of interest to all physicians and researchers in this field around the globe.
Contents
Part I. Diagnosis and Risk Factors of AKI -- 1. Acute Kidney Injury: Definition and Epidemiology -- 2. Causes of AKI (Prerenal, Intrarenal, Postrenal) -- 3. Pathophysiology of AKI -- 4. Diagnosis of AKI: Clinical Assessment, Novel Biomarkers, History, and Perspectives -- 5. Risk Factors for AKI Development in Surgery (Non-cardiac Surgery) -- 6. Risk Factors for AKI Development in Acute Decompensated Heart Failure -- 7. Contrast-Induced Acute Kidney Injury -- 8. Antibiotics- and Immunosuppressants-Related AKI -- 9. AKI in Setting of Cancer -- 10. Community- and Hospital-Acquired Acute Kidney Injury -- Part II. Complication of AKI -- 11. Complication of Homeostasis (Electrolytes and Acid-Base) -- 12. Volume Overload and Pulmonary Complications -- Part II.I Prevention and Management of AKI -- 13. Prophylaxis and Management of Acute Kidney Injury -- 14. Postrenal AKI -- 15. Acute Kidney Injury in Intensive Care Medicine -- 16. Nondialytic Supportive Management of AKI -- 17. Renal Replacement Therapy in AKI -- 18. Short-Term and Long-Term Outcomes of AKI Patients -- 19. Management of Pediatric AKI -- Part IV. Experimental Novel Findings -- 20. AKI-to-CKD Transition -- 21. Role of the Nervous System in Acute Kidney Injury -- 22. AKI and Immune System -- 23. Acute Kidney Injury and Cytokines -- Part V. AKI and Regenerative Medicine -- 24. iPS Cell and Renal Regenerative Medicine -- 25. Kidney Development and Injury: A Road to Regeneration -- 26. Xenotransplanted Embryonic Kidney.
Format
e-Book
Location
Online
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Management of Acute Kidney Problems

https://libcat.nshealth.ca/en/permalink/provcat29242
edited by Achim Jörres, Claudio Ronco, John A. Kellum. --Berlin, Heidelberg: Springer-Verlag , c2010.
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Online
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Author
Jörres, Achim
Other Authors
Ronco, Claudio
Kellum, John A
Responsibility
edited by Achim Jörres, Claudio Ronco, John A. Kellum
Place of Publication
Berlin, Heidelberg
Publisher
Springer-Verlag
Date of Publication
c2010
ISBN
9783540694410
Subjects (MeSH)
Acute Kidney Injury - therapy
Subjects (LCSH)
Critical care medicine
Nephrology
Format
e-Book
Location
Online
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Perioperative Kidney Injury : Principles of Risk Assessment, Diagnosis and Treatment

https://libcat.nshealth.ca/en/permalink/provcat38939
Charuhas V. Thakar, Chirag R. Parikh, editors. --New York, NY: Springer , c2015.
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The kidneys participate in all vital processes of the body to maintain overall homeostasis and health. When kidneys are injured during surgical interventions, metabolic and hemodynamic control is disrupted, leading to dysfunction associated with greater mortality, length of hospital stay, and cost. Peri-operative Kidney Injury presents the epidemiology, risk factors, diagnosis, treatment, and outcomes associated with kidney injury during the peri-operative period. Concepts and principles of car…
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Other Authors
Thakar, Charuhas V
Parikh, Chirag R
Responsibility
Charuhas V. Thakar, Chirag R. Parikh, editors
Place of Publication
New York, NY
Publisher
Springer
Date of Publication
c2015
Physical Description
1 online resource (xvii, 251 p. : 21 illus., 15 illus. in color)
ISBN
9781493912735
9781493912728 (print ed.)
Subjects (MeSH)
Acute Kidney Injury - diagnosis
Acute Kidney Injury - therapy
Postoperative Complications
Risk Factors
Abstract
The kidneys participate in all vital processes of the body to maintain overall homeostasis and health. When kidneys are injured during surgical interventions, metabolic and hemodynamic control is disrupted, leading to dysfunction associated with greater mortality, length of hospital stay, and cost. Peri-operative Kidney Injury presents the epidemiology, risk factors, diagnosis, treatment, and outcomes associated with kidney injury during the peri-operative period. Concepts and principles of care to prevent kidney complications during surgical procedures are provided to equip health care professionals along with strategies to manage acute kidney injury and associated challenges when they occur. Chapters detail diverse surgical settings, ranging from the more common, such as abdominal, cardiac, and vascular surgeries, to the intricately complex, including the use of the left ventricular assist device and organ transplants. This practical and comprehensive text blends the evidence-based standards of care with cutting edge advances in the field, while also providing the reader with a peek into innovations on the horizon.
Contents
Part I Peri-operative AKI: Overview and Approach -- 1 Incidence, Trends and Diagnosis of Peri-operative AKI -- 2 Serious peri-operative complications: Hospital Medicine Perspectives -- 3 Role of Novel Kidney Injury Biomarkers in Perioperative AKI -- 4 Clinical Pearls: Renal Replacement Therapy for AKI in the Post-operative Period -- 5 Clinical Pearls: Non-dialytic Management of Kidney Complications in the Post-operative Period -- 6 Intra-Operative Considerations to Prevent Post-Operative AKI -- Part II Cardiac and Vascular Surgery -- 7 AKI after Cardiac Surgery in Adults -- 8 AKI after Cardiovascular Surgery in Children -- 9 AKI in the Era of Ventricular Assist Devices -- 10 Kidney Injury after Vascular Surgery -- Part III Abdominal and Urologic Surgery -- 11 AKI after Major Abdominal Surgery: Epidemiology and Management Challenges -- 12 Kidney Injury in Abdominal Compartment Syndrome -- 13 Kidney Function and Injury after Nephrectomy for Kidney Cancer -- Part IV Transplant Surgery -- 14 The Kidney in Non-Renal Solid Organ Transplantation: Liver and Heart -- 15 Acute Allograft Injury After Kidney Transplantation -- Part V Special Topics in Peri-operative AKI -- 16 Trauma and Acute Kidney Injury -- 17 Fluid-Electrolyte Imbalances and Extra-Corporeal Therapy in the Neurosurgical Setting -- 18 Nutrition in Peri-operative Patients with Kidney Failure.
Format
e-Book
Location
Online
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Reducing Mortality in Acute Kidney Injury

https://libcat.nshealth.ca/en/permalink/provcat40246
Giovanni Landoni, Antonio Pisano, Alberto Zangrillo, Rinaldo Bellomo, editors. --Cham: Springer , c2016.
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This book describes the techniques, strategies, and drugs that have been demonstrated by at least one paper published in a peer-reviewed journal to significantly influence survival in patients with or at risk for acute kidney injury. Each chapter focuses on a specific intervention. The scope is accordingly wide, with coverage of topics as diverse as the type, timing, and dose of renal replacement therapy (RRT), anticoagulation and specific indications for RRT, perioperative hemodynamic optimiza…
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Other Authors
Landoni, Giovanni
Pisano, Antonio
Zangrillo, Alberto
Bellomo, Rinaldo
Responsibility
Giovanni Landoni, Antonio Pisano, Alberto Zangrillo, Rinaldo Bellomo, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2016
Physical Description
1 online resource (ix, 203 p. : 10 illus., 9 illus. in color)
ISBN
9783319334295
9783319334271 (print ed.)
Subjects (MeSH)
Acute Kidney Injury - mortality
Acute Kidney Injury - therapy
Kidney - injuries
Abstract
This book describes the techniques, strategies, and drugs that have been demonstrated by at least one paper published in a peer-reviewed journal to significantly influence survival in patients with or at risk for acute kidney injury. Each chapter focuses on a specific intervention. The scope is accordingly wide, with coverage of topics as diverse as the type, timing, and dose of renal replacement therapy (RRT), anticoagulation and specific indications for RRT, perioperative hemodynamic optimization, fluid balance, diuretics, colloids, fenoldopam, terlipressin, N-acetylcysteine, and vasopressin. A variety of settings are considered, including critically ill patients, cardiac surgery, and hepatic and hematologic disorders. The topic selection was made using a democracy-based approach in which hundreds of specialists from dozens of countries expressed, via the web, whether they agreed with these topics and whether they used the techniques in their daily clinical practice. The clear text is supported by "how to do" sections and "key point" boxes that provide easily accessible practical information. The book will be of interest for a wide variety of specialists, including intensivists, nephrologists, emergency doctors, and anesthesiologists.
Contents
Part I. Introduction -- Acute kidney injury: the plague of the new millennium -- Acute kidney injury: definitions, incidence, diagnosis, and outcome -- Reducing mortality in acute kidney injury: the democracy-based approach to consensus -- Part II. Interventions that may reduce mortality -- Continuous renal replacement therapy vs. intermittent hemodialysis: impact on clinical outcomes -- May an "early" renal replacement therapy improve survival? -- Increased intensity of renal replacement therapy to reduce mortality in patients with acute kidney injury -- Citrate anticoagulation to reduce mortality in patients needing continuous renal replacement therapy -- Peri-angiography hemofiltration to reduce mortality -- Continuous venovenous hemofiltration to reduce mortality in severely burned patients -- Perioperative hemodynamic optimization to reduce acute kidney injury and mortality in surgical patients -- Furosemide by continuous infusion to reduce mortality in patients with acute kidney injury -- N-acetylcysteine to reduce mortality in cardiac surgery -- Fenoldopam and acute kidney injury. Is it time to turn the page? -- Vasopressin to reduce mortality in patients with septic shock and acute kidney injury -- Terlipressin reduces mortality in hepatorenal syndrome -- Albumin to reduce mortality in cirrhotic patients with acute kidney injury -- Extracorporeal removal of serum free light chains in patients with multiple-myeloma associated acute kidney injury -- Can intravenous human immunoglobulins reduce mortality in patients with (septic) acute kidney injury? -- Part III. Interventions that may increase mortality -- Fluid overload may increase mortality in patients with acute kidney injury -- Hydroxyethyl starch, acute kidney injury, and mortality -- Loop diuretics and mortality in patients with acute kidney injury -- Part IV. Update -- Reducing mortality in patients with acute kidney injury: a systematic update.
Format
e-Book
Location
Online
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Renal Failure and Replacement Therapies

https://libcat.nshealth.ca/en/permalink/provcat28277
edited by Sara Blakeley. --London: Springer-Verlag , c2008.
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Online
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Author
Blakeley, Sara
Responsibility
edited by Sara Blakeley
Place of Publication
London
Publisher
Springer-Verlag
Date of Publication
c2008
Series Title
Competency-Based Critical Care
ISBN
9781846289378
Subjects (MeSH)
Acute Kidney Injury - therapy
Renal Replacement Therapy
Subjects (LCSH)
Critical care medicine
Nephrology
Format
e-Book
Location
Online
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