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Adult Vaccinations : Changing the Immunization Paradigm

https://libcat.nshealth.ca/en/permalink/provcat44121
Jean-Pierre Michel, Stefania Maggi, editors. --Cham: Springer , 2019.
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After introductory chapters devoted to the safe production and distribution of vaccines, the book addresses the question of adult vaccination in the framework of a life-course approach to vaccination. It presents the proceedings of multidisciplinary expert discussions with an excellent summary of the current state of knowledge on adult vaccination in various diseases, as well as an overview of the professionals involved and the obstacles to achieving greater vaccine uptake, and how these may be…
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Other Authors
Michel, Jean-Pierre
Maggi, Stefania
Responsibility
Jean-Pierre Michel, Stefania Maggi, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
2019
Physical Description
1 online resource (viii, 127 p.) : 1 illus. in color
Series
Practical Issues in Geriatrics
Series Title
Practical issues in geriatrics
ISBN
9783030051594
9783030051587 (Print ed.)
9783030051600 (Print ed.)
ISSN
2509-6060
Subjects (MeSH)
Adult
Aging - immunology
Immunization
Vaccination
Vaccines
Specialty
Public Health
Abstract
After introductory chapters devoted to the safe production and distribution of vaccines, the book addresses the question of adult vaccination in the framework of a life-course approach to vaccination. It presents the proceedings of multidisciplinary expert discussions with an excellent summary of the current state of knowledge on adult vaccination in various diseases, as well as an overview of the professionals involved and the obstacles to achieving greater vaccine uptake, and how these may be addressed. The book systematically discusses the major vaccine-preventable diseases, as well as regulatory issues in vaccine provision, and presents the results of an expert meeting designed to identify the obstacles to vaccination, and solutions for addressing these barriers. It goes on to extend the discussion beyond the traditional boundaries of human health to encompass the “one health” concept. The book is intended for all those with an interest in vaccination, including physicians (from a wide range of disciplines including geriatrics/gerontology, infectious diseases, pediatrics, internal medicine, and other non-organ specialties), other healthcare professionals, pharmacists, representatives of the pharmaceutical industry and regulatory bodies (EMEA, national authorities), policymakers, the media and the general public.
Contents
Foreword. Adult vaccinations: essential but too often forgotten -- 1. Complexity of vaccine manufacture and supply -- 2. Administration of vaccines: current process, new technologies, adjuvants -- 3. How can the European Medicines Agency support an appropriate strategy of adult vaccination? -- 4. Public health impact of adult vaccine-preventable diseases on performance, disability, mortality and health care costs in Europe -- 5. Outcomes after HPV vaccination -- 6. Impact of nutrition on adult vaccination efficacy -- 7. Profiling vaccines for an immunosenescent and multimorbid population -- 8. Comprehensive geriatric assessment in infectious diseases -- 9. Etiology of respiratory tract infections in adults in Europe: current knowledge and knowledge gaps -- 10. European flu vaccine regulations and their impacts in community-dwelling adults -- 11. Vaccination against pneumococcal disease in the European Union, with particular focus on Germany -- 12. Direct and indirect benefits of a comprehensive approach to vaccinating adults with influenza and pneumococcal vaccines, especially in patients with chronic diseases -- 13. Vaccination of health care professionals and protection of hospitalized adults and nursing home residents -- 14. Ongoing threats for older Europeans: Diphtheria, Pertussis and Tetanus -- 15. Herpes Zoster vaccination: a vaccine to prevent pain -- 16. Gastroenteritis burden in the adult community: prospects for vaccines -- 17. Travel vaccination -- 18. Integrating the veterinarian scientist to the one-health concept -- 19. Stressing the importance of adult immunization: suggestions for how to change the paradigm -- 20. How can we integrate life course vaccination into the new WHO definition of “Healthy Ageing”?.
Format
e-Book
Location
Online
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The Ageing Immune System and Health

https://libcat.nshealth.ca/en/permalink/provcat41474
Valquiria Bueno, Janet M. Lord, Thomas A. Jackson, editors. --Cham: Springer , 2017.
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The present book intends to provide an update on immunosenescence and how deficiencies in the immune system contribute to a higher susceptibility to infections, decline in organ function, reduced vaccination responses, age-related disease and the ageing process itself, negatively affecting longevity. Our focus is on the main changes in immune system cells and their products occurring during the ageing process and the possible consequences for health and disease. This includes: discussion of the…
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Other Authors
Bueno, Valquiria
Lord, Janet M
Jackson, Thomas A
Responsibility
Valquiria Bueno, Janet M. Lord, Thomas A. Jackson, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
2017
Physical Description
1 online resource (xii, 182 pages) : 19 illus., 11 illus. in color
ISBN
9783319433653
9783319433639 (print ed.)
Subjects (MeSH)
Aging - immunology
Immune System - physiopathology
Immunosenescence
Abstract
The present book intends to provide an update on immunosenescence and how deficiencies in the immune system contribute to a higher susceptibility to infections, decline in organ function, reduced vaccination responses, age-related disease and the ageing process itself, negatively affecting longevity. Our focus is on the main changes in immune system cells and their products occurring during the ageing process and the possible consequences for health and disease. This includes: discussion of the modulatory and/or suppressive mechanisms associated with the alterations in T regulatory cells, B regulatory cells and Myeloid Derived Suppressor cells; changes in the immune system observed in chronic neurodegenerative diseases, cancer, lung disease and frailty will also be discussed. Most importantly we provide recent literature information about possible interventions (focusing on physical activity) that could alleviate the negative effects of immunosenescence. The Ageing Immune System and Health is a comprehensive guide on the field intended to all physicians, researchers, professors and students interested on relationship between immune system, ageing and health.
Contents
1. Innate Immunosenescence and Its Impact on Health in Old Age -- 2. Effects of Ageing on Adaptive Immune Responses -- 3. The DNA Methylome: An Interface Between the Environment, Immunity, and Ageing -- 4. The Role of CMV in Immunosenescence -- 5. Effects of Ageing on the Vaccination Response -- 6. Immunosenescence and the Ageing Lung -- 7. Cancer, Ageing and Immunosenescence -- 8. Immune to Brain Communication in Health, Age and Disease: Implications for Understanding Age-Related Neurodegeneration -- 9. Frailty and Ageing -- 10. Lifestyle Interventions to Improve Immunesenescence.
Format
e-Book
Location
Online
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Immunology of aging

https://libcat.nshealth.ca/en/permalink/provcat33805
Ahmad Massoud, Nima Rezaei, editors. --Heidelberg: Springer , c2014.
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Location
Online
Available Online
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Other Authors
Massoud, Ahmad
Rezaei, Nima
Responsibility
Ahmad Massoud, Nima Rezaei, editors
Place of Publication
Heidelberg
Publisher
Springer
Date of Publication
c2014
Physical Description
1 online resource (xix, 406 pages)
ISBN
9783642394959 (electronic bk.)
9783642394942
Subjects (MeSH)
Aging - immunology
Immune System Phenomena - physiology
Subjects (LCSH)
Immunology
Geriatrics
Emerging infectious diseases
Contents
An introduction on the old age and aging of the immune system -- The immune system, a marker and modulator of the rate of aging -- Age-associated alterations of pleiotropic stem cell and the therapeutic implication of stem cell therapy in aging -- A role for epigenetic modulation of the innate immune response during aging -- Basophil, eosinophil and neutrophil functions in the elderly -- Dendritic cells and dysregulated immunity in the elderly -- Natural killer cell immunosenescence and cancer in the elderly -- Pattern recognition receptors and aging -- Impact of ageing on T cell repertoire and immunity -- T cell mediated immunity in the immunosenescence process -- Biological and phenotypic alterations of T cells in aging -- T cells seen from the metabolic and aging perspective -- Age-related alterations in regulatory T cells -- Effects of aging on B cells -- The role of MicroRNAs in immunosenescence process -- Immunogenetics of Aging -- Aging immunity and infection -- Influenza infection in the elderly -- Optimising response to vaccination in the elderly -- Nutrition, immunity and aging -- Diet and immunosenescence -- Dietary Intake and impact of zinc supplementation on the immune functions in elderly: nutrigenomic approach -- Physiological and pathological role of reactive oxygen species in the immune cells -- Oxidative stress and aging -- Skin aging and the immune system -- Aging immunity and the impact of physical exercise.
Format
e-Book
Location
Online
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