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Active living, cognitive functioning, and aging

https://libcat.nshealth.ca/en/permalink/provcat22851
Poon, Leonard W. --Champaign, IL: Human Kinetics , 2006.
Call Number
WT 104 A267 2006
Location
Halifax Infirmary
Call Number
WT 104 A267 2006
Author
Poon, Leonard W
Other Authors
Chodzko-Zajko, Wojtek
Tomporowski, Phillip D
Place of Publication
Champaign, IL
Publisher
Human Kinetics
Date of Publication
2006
Physical Description
250 p.
Series Vol.
v. 1
Series Title
Aging, exercise, and cognition series
ISBN
0736057854
9780736057851
Subjects (MeSH)
Aging - physiology
Cognition - physiology - aged
Exercise - physiology - Aged
Health Behavior - Aged
Physical Fitness - Aged
Format
Book
Location
Halifax Infirmary
Loan Period
3 weeks
Less detail

Advances in Geroscience

https://libcat.nshealth.ca/en/permalink/provcat39908
Felipe Sierra, Ronald Kohanski, editors. (1st ed.) --Cham: Springer , c2016.
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Location
Online
This book provides the first comprehensive overview of a new scientific discipline termed Geroscience. Geroscience examines the molecular and cellular mechanisms that might explain why aging is the main risk factor for most chronic diseases affecting the elderly population. Over the past few decades, researchers have made impressive progress in understanding the genetics, biology and physiology of aging. This book presents vital research that can help readers to better understand how aging is a…
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Other Authors
Sierra, Felipe
Kohanski, Ronald
Responsibility
Felipe Sierra, Ronald Kohanski, editors
Edition
1st ed.
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2016
Physical Description
1 online resource (xxiii, 622 p. : 39 illus.)
ISBN
9783319232461
9783319232454 (print ed.)
Subjects (MeSH)
Aging - physiology
Chronic Disease
Geriatrics
Risk Factors
Abstract
This book provides the first comprehensive overview of a new scientific discipline termed Geroscience. Geroscience examines the molecular and cellular mechanisms that might explain why aging is the main risk factor for most chronic diseases affecting the elderly population. Over the past few decades, researchers have made impressive progress in understanding the genetics, biology and physiology of aging. This book presents vital research that can help readers to better understand how aging is a critical malleable risk factor in most chronic diseases, which, in turn, could lead to interventions that can help increase a healthy lifespan, or "healthspan". The book begins with an analysis of the Geroscience hypothesis, as well as the epidemiological underpinnings that define aging as a candidate main risk factor for most chronic diseases. Next, each chapter focuses on one particular disease, or group of diseases, with an emphasis on how basic molecular and cellular biology might explain why aging is a major risk factor for it. Coverage in the book includes: cancer, cardiovascular disease, dementias, stroke, Parkinson's and Alzheimer's diseases, osteoporosis, arthritis, diabetes asthma, emphysema, kidney disease, vision impairment, and AIDS/HIV. It finishes with a chapter on pain in the elderly and an overview of future steps needed to bring the newly acquired knowledge into the clinic and the public at large.
Contents
The Geroscience Hypothesis: Is It Possible to Change the Rate of Aging? / Steven N. Austad -- Etiological Role of Aging in Chronic Diseases: From Epidemiological Evidence to the New Geroscience / Linda P. Fried and Luigi Ferrucci -- The Impact of Aging on Cancer Progression and Treatment / Shenghui He and Norman E. Sharpless -- The Impact of Cancer Treatments on Aging / Changhan Lee and Valter Longo -- Cardiovascular Disease and Aging / Ying Ann Chiao, Edward Lakatta, Zoltan Ungvari, Dao-Fu Dai and Peter Rabinovitch -- The Impact of Aging on Ischemic Stroke / Farida Sohrabji -- Parkinson's Disease and Aging / Julie K. Andersen -- The Role of Aging in Alzheimer's Disease / Geoffrey A. Kerchner and Tony Wyss-Coray -- Aging and the Bone-Muscle Interface / Simon Melov and Clifford J. Rosen -- Osteoporosis and Mechanisms of Skeletal Aging / Julie Glowacki and Tamara Vokes -- Osteoarthritis in the Elderly / Richard F. Loeser and Martin Lotz -- Diabetes and Aging / Nicolas Musi and Andrzej Bartke -- Renal Aging and Transplantation / John P. Higgins and Stuart K. Kim -- Asthma and Aging / Nicola A. Hanania and Paula Busse -- Aging in COPD and Idiopathic Pulmonary Fibrosis / Cecilia Sanchez -- Age-Related Macular Degeneration and Vision Impairment / Jayakrishna Ambati and Charles Wright -- HIV and Aging: Parallels and Synergistic Mechanisms Leading to Premature Disease and Functional Decline / Anna Hearps, Katherine Schafer, Kevin High and Alan Landay -- Pain in the Elderly / Roger B. Fillingim, Dennis C. Turk and Robert P. Yezierski -- The Way Forward / translation: James L. Kirkland.
Format
e-Book
Location
Online
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Age-Related Changes of the Human Eye

https://libcat.nshealth.ca/en/permalink/provcat29975
edited by Carlo A. P. Cavallotti, Luciano Cerulli. --Totowa, NJ: Humana Press , c2008.
Available Online
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Location
Online
Available Online
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Author
Cavallotti, Carlo A. P
Other Authors
Cerulli, Luciano
Responsibility
edited by Carlo A. P. Cavallotti, Luciano Cerulli
Place of Publication
Totowa, NJ
Publisher
Humana Press
Date of Publication
c2008
Series Title
Aging medicine
ISBN
9781597455077
Subjects (MeSH)
Aging - physiology
Eye Diseases - physiopathology
Subjects (LCSH)
Geriatrics
Ophthalmology
Format
e-Book
Location
Online
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Aging and heart failure : mechanisms and management

https://libcat.nshealth.ca/en/permalink/provcat33590
Bodh I. Jugdutt, editor. --New York: Springer , c2014.
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Location
Online
This book synthesizes the major research advances in molecular, biochemical, and translational aspects of aging and heart failure over the last four decades and addresses future directions in management and drug discovery. It presents clinical issues and molecular mechanisms related to heart failure, including the changing demographics in the aging population with heart failure; hypertension and prevention of diastolic heart failure in the aging population; polypharmacy and adverse drug reactio…
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Other Authors
Jugdutt, Bodh I
Responsibility
Bodh I. Jugdutt, editor
Place of Publication
New York
Publisher
Springer
Date of Publication
c2014
Physical Description
1 online resource
ISBN
9781493902682 (electronic bk.)
9781493902675
Subjects (MeSH)
Aging - physiology
Heart Failure
Subjects (LCSH)
Heart failure
Older people - Medical care
Abstract
This book synthesizes the major research advances in molecular, biochemical, and translational aspects of aging and heart failure over the last four decades and addresses future directions in management and drug discovery. It presents clinical issues and molecular mechanisms related to heart failure, including the changing demographics in the aging population with heart failure; hypertension and prevention of diastolic heart failure in the aging population; polypharmacy and adverse drug reactions in the aging population with heart failure; changes in the heart that accompany advancing age from humans to molecules; aging-associated alterations in myocardial inflammation and fibrosis; and aging-related changes in mitochondrial function and implications for heart failure therapy. The book succinctly summarizes the large volume of data on these key topics and highlights novel pathways that need to be explored. Featuring contributions from leading clinician-scientists, Aging and Heart Failure: Mechanisms and Management is an authoritative resource on the major clinical issues in heart failure therapy in the elderly for cardiologists, gerontologists, and internists.
Contents
Changing Demographics of the Aging Population with Heart Failure and Implications for Therapy -- Biology of Aging and Implications for Heart Failure Therapy and Prevention -- Hypertension and Prevention of Diastolic Heart Failure in the Aging Population -- Aging and Optimal Therapy of Systolic Heart Failure in the Elderly -- Atrial Fibrillation and Heart Failure in the Aging Population -- Optimizing Therapy of Heart Failure in the Aging Population with Monitoring in Clinics -- Cardiac Alterations in Aging, Hypertension, and Diastolic Heart Failure -- Polypharmacy and Adverse Drug Reactions in the Aging Population with Heart Failure -- Age-Related Changes in Vascular Biology and Implications for Heart Failure Therapy in the Aging Population -- Biomarkers and Optimal Management of Heart Failure in the Aging Population -- Benefits of Exercise in the Elderly -- The RAAS in Heart Failure: An Update on Clinical Trials and Opportunities for Therapy -- Aging and Diastolic Dysfunction: The Interplay of Inflammation and Extracellular Matrix Regulation -- Reperfusion and Vasodilator Therapy in Elderly Patients with STEMI and Heart Failure: Improving Outcomes -- Erythropoietin Therapy for Heart Failure -- Role of Resistin in Heart Failure in the Elderly -- Role of Coronary Artery Calcium in Cardiovascular Risk Stratification and Management in the Aging Population -- Aging and Remodeling of the RAS and RAAS and Related Pathways: Implications for Heart Failure Therapy -- Aging and Right Ventricular Failure from Pulmonary Hypertension: Effect of Right Ventricular and Pulmonary Artery Remodeling -- Aging and Right Ventricular Failure from Pulmonary Hypertension: Effect of Right Ventricular and Pulmonary Artery Remodeling -- Biomarkers of Cardiovascular Aging -- Changes in the Heart That Accompany Advancing Age: Humans to Molecules -- Aging-Related Changes in Cell Death and Cell Survival Pathways and Implications for Heart Failure Therapy -- Aging-Related Changes in Telomeres and Telomerases and Implications for Heart Failure Therapy -- Aging-Associated Alterations in Myocardial Inflammation and Fibrosis: Pathophysiological Perspectives and Clinical Implications -- Aging-Related Changes in Extracellular Matrix: Implications for Ventricular Remodeling Following Myocardial Infarction -- Calcium-Handling Defects and Changes in Cardiac Function in the Aging Heart -- Integrins: Implications for Aging in Heart Failure Therapy -- Adipokines as Novel Biomarkers in Aging and Heart Failure -- Aging-Related Changes in Cellular and Molecular Mechanisms of Postinfarction Remodeling: Implications for Heart Failure Therapy -- Aging-Related Changes in Mitochondrial Function and Implication for Heart Failure Therapy -- Regulation of SERCA Via Oxidative Modifications: Implications for the Pathophysiology of Diastolic Dysfunction in the Aging Heart -- SMP30 and Aging-Related Cardiac Remodeling and Heart Failure.
Format
e-Book
Location
Online
Less detail

Aging and the heart : A Post-Genomic View

https://libcat.nshealth.ca/en/permalink/provcat28046
by José Marín-García, Michael J. Goldenthal, Gordon W. Moe. --Boston, MA: Springer Science+Business Media , c2008.
Available Online
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Location
Online
Available Online
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Author
Marín-García, José
Other Authors
Goldenthal, Michael J
Moe, Gordon W
Responsibility
by José Marín-García, Michael J. Goldenthal, Gordon W. Moe
Place of Publication
Boston, MA
Publisher
Springer Science+Business Media
Date of Publication
c2008
ISBN
9780387740720
Subjects (MeSH)
Aging - physiology
Cardiovascular Diseases - genetics
Cardiovascular Diseases - physiopathology
Subjects (LCSH)
Cardiology
Geriatrics
Format
e-Book
Location
Online
Less detail
--Berlin, Heidelberg: Springer-Verlag , c2010.
Available Online
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Location
Online
Available Online
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Other Authors
Trüeb, Ralph M
Tobin, Desmond J
Place of Publication
Berlin, Heidelberg
Publisher
Springer-Verlag
Date of Publication
c2010
ISBN
9783642026362
Subjects (MeSH)
Aging - physiology
Hair Diseases - aged
Hair - physiology
Subjects (LCSH)
Dermatology
Geriatrics
Format
e-Book
Location
Online
Less detail

The aging kidney in health and disease

https://libcat.nshealth.ca/en/permalink/provcat30341
--Boston, MA: Springer Science+Business Media , c2008.
Available Online
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Location
Online
Available Online
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Other Authors
Macias Nuñez, Juan F
Cameron, J. Stewart
Oreopoulos, Dimitrios G
Place of Publication
Boston, MA
Publisher
Springer Science+Business Media
Date of Publication
c2008
ISBN
9780387726595
Subjects (MeSH)
Aging - physiology
Kidney - physiology
Kidney Diseases
Subjects (LCSH)
Geriatrics
Nephrology
Format
e-Book
Location
Online
Less detail

Aging : the paradox of life : why we age

https://libcat.nshealth.ca/en/permalink/provcat30359
Holliday, Robin. --Dordrecht: Springer , c2007.
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Location
Online
Available Online
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Author
Holliday, Robin
Place of Publication
Dordrecht
Publisher
Springer
Date of Publication
c2007
ISBN
9781402056413
Subjects (MeSH)
Aging - physiology
Subjects (LCSH)
Geriatrics
Format
e-Book
Location
Online
Less detail

American Psychiatric Association Publishing textbook of geriatric psychiatry, The

https://libcat.nshealth.ca/en/permalink/provcat50335
Steffens, David O. (5th ed.) --Arlington, VA: American Psychiatric Publishing , 2015.
Available Online
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Location
Online
Available Online
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Author
Steffens, David O.
Other Authors
Blazer, Dan G.
Thakur, Mugdha E.
Edition
5th ed.
Place of Publication
Arlington, VA
Publisher
American Psychiatric Publishing
Date of Publication
2015
ISBN
9781615370054
Subjects (MeSH)
Mental Disorders
Aged
Aging - physiology
Geriatric Psychiatry - methods
Notes
Access to this online resource is restricted to IWK Health Centre employees working from inside the hospital network.
Format
e-Book
Location
Online
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The American Psychiatric Publishing textbook of geriatric psychiatry

https://libcat.nshealth.ca/en/permalink/provcat42249
edited by David C. Steffens, Dan G. Blazer, Mugdha E. Thakur. (Fifth edition) --Washington, DC: American Psychiatric Publishing , c2015.
Available Online
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Location
Online
Available Online
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Responsibility
edited by David C. Steffens, Dan G. Blazer, Mugdha E. Thakur
Edition
Fifth edition
Place of Publication
Washington, DC
Publisher
American Psychiatric Publishing
Date of Publication
c2015
Physical Description
1 online resource [xiv, 823 pages]
ISBN
9781615370054
9781585624843
Subjects (MeSH)
Aged - psychology
Aging - physiology
Geriatric Psychiatry - methods
Mental Disorders
Contents
Part I: Introduction to Geriatric Psychiatry -- Demography and epidemiology of psychiatric disorders in late life -- Physiological and clinical considerations of geriatric patient care -- Genomics in geriatric psychiatry -- Part II. Evaluation of Psychiatric Disorders in Late Life -- The psychiatric interview of older adults -- Use of the laboratory in the diagnostic workup of older adults -- Neuropsychological assessment of dementia -- Part III: Presentation of Psychiatric Disorders in Late Life -- Delirium -- Dementia and mild neurocognitive disorders -- Mood disorders -- Bipolar disorder in late life -- Schizophrenia spectrum and other psychotic disorders -- Anxiety disorders -- Somatic symptom and related disorders -- Sexuality and aging -- Bereavement -- Sleep and circadian rhythm disorders -- Alcohol and drug problems -- Personality disorders -- Agitation in older adults -- Part IV: Treatment of Psychiatric Disorders in Late Life -- Psychopharmacology -- Electroconvulsive therapy and other forms of brain stimulation -- Nutrition and physical activity -- Individual and group psychotherapy -- Working with families of older adults -- Clinical psychiatry in the nursing home.
Format
e-Book
Location
Online
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The American Psychiatric Publishing textbook of geriatric psychiatry

https://libcat.nshealth.ca/en/permalink/provcat23835
Blazer, Dan G. (4th ed.) --Washington, DC: American Psychiatric Pub. , 2009.
Call Number
WT 150 A512 2009
Location
Halifax Infirmary
Call Number
WT 150 A512 2009
Author
Blazer, Dan G
Other Authors
Steffens, David C
Edition
4th ed.
Place of Publication
Washington, DC
Publisher
American Psychiatric Pub.
Date of Publication
2009
Physical Description
676 p.
ISBN
9781585622771
Subjects (MeSH)
Geriatric Psychiatry
Mental Disorders - Aged
Aging - physiology
Format
Book
Location
Halifax Infirmary
Loan Period
3 weeks
Less detail

Biological Basis of Geriatric Oncology

https://libcat.nshealth.ca/en/permalink/provcat29596
edited by Lodovico Balducci, Martine Extermann. --Boston, MA: Springer Science+Business Media , c2005.
Available Online
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Location
Online
Available Online
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Author
Balducci, Lodovico
Other Authors
Extermann, Martine
Responsibility
edited by Lodovico Balducci, Martine Extermann
Place of Publication
Boston, MA
Publisher
Springer Science+Business Media
Date of Publication
c2005
Series Vol.
124
Series Title
Cancer treatment and research
ISBN
9780387239620
Subjects (MeSH)
Neoplasms - epidemiology - Aged
Aging - physiology
Comorbidity
Subjects (LCSH)
Geriatrics
Oncology
Format
e-Book
Location
Online
Less detail

The biology of human longevity : inflammation, nutrition, and aging in the evolution of lifespans

https://libcat.nshealth.ca/en/permalink/provcat27590
Finch, Caleb E. --Amsterdam, Netherlands: Elsevier Academic Press , 2007.
Available Online
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Location
Online
Available Online
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Author
Finch, Caleb E
Place of Publication
Amsterdam, Netherlands
Publisher
Elsevier Academic Press
Date of Publication
2007
Physical Description
626 p.
ISBN
9780080545943
Subjects (MeSH)
Longevity - physiology
Aging - physiology
Inflammation
Nutritional Physiological Phenomena
Contents
1. INFLAMMATION AND OXIDATION IN AGING AND CHRONIC DISEASES. 1.1. Overview ; 1.2. Experimental models for aging ; 1.3. Outline of inflammation ; 1.4. Bystander damage and dependent variables in senescence ; 1.5 Arterial aging and atherosclerosis ; 1.6. Alzheimer disease and vascular-related dementias ; 1.7. Inflammation in obesity ; 1.8. Processes of normal aging in the absence of specific diseases ; 1.9. Summary -- 2. INFECTIONS, INFLAMMOGENS, AND DRUGS. 2.1. Introduction ; 2.2. Vascular disease ; 2.3. Infections from the central tube : Metchnikoff revisited ; 2.4. Aerosols and dietary inflammogens ; 2.5. Infections, inflammation, and life span ; 2.6. Are infections a cause of obesity? ; 2.7. Inflammation, dementia, and cognitive decline ; 2.8. Immunosenescence and stem cells ; 2.9. Cancer, infection, and inflammation ; 2.10. Pharmacopleiotropies in vascular disease, dementia, and cancer ; 2.11. Summary -- 3. ENERGY BALANCE, INFLAMMATION, AND AGING. 3.1. Introduction ; 3.2. Diet restriction and aging ; 3.3. Energy sensing in diet restriction and satiety ; 3.4. Exercise, cardiovascular health, and longevity ; 3.5. Diet, exercise, and neurodegeneration ; 3.6. Laboratory rodents as models for the 'couch potato' ; 3.7. Energy balance in the life history ; 3.8. Summary -- 4. NUTRITION AND INFECTION IN THE DEVELOPMENTAL INFLUENCES ON AGING. 4.1. Introduction ; 4.2. Synopsis of the fetal origins theory ; 4.3. The Barker studies of infections and vascular disease ; 4.4. Size, health, and longevity ; 4.5. Infection and undernutrition on birthweight and later disease ; 4.6. Infection and nutrition in postnatal development and later disease ; 4.7. Famine ; 4.8. Maternal physiology, fetal growth, and later chronic disease ; 4.9. Growth in adaptive responses to the environment ; 4.10. Genomics of fetal growth regulation ; 4.11. Summary -- 5. GENETICS. 5.1. Introduction ; 5.2. Sources of individual variations in aging and life span ; 5.3. Sex differences in longevity ; 5.4. Metabolism and host-defense in worm and fly ; 5.5. The worm ; 5.6. Fly ; 5.7. Mammals ; 5.8. Summary -- 6. THE HUMAN LIFE SPAN : PRESENT, PAST, AND FUTURE. 6.1. Introduction ; 6.2. From great ape to human ; 6.3. Four major shifts in human life history from genetic and cultural evolution ; 6.4. The instability of life spans ; 6.5. Summary of chapters 1-6 : mechanisms in aging and life history evolution.
Format
e-Book
Location
Online
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The Biology of Senescence : A Translational Approach

https://libcat.nshealth.ca/en/permalink/provcat44359
Bernard Swynghedauw. --Cham: Springer , c2019.
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Location
Online
This book describes the fundamental process of senescence, and reviews a new concept developed by a number of research groups that is based on cellular senescence and its secretome. This concept provides a basic explanation of the main physiological and pathological features of senescence, and delineates possibilities for “treating” it. Following an introduction to the emerging medical landscape, the increasing incidence of a new epidemiological group (age-related “chronic non-transmissible dis…
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Author
Swynghedauw, Bernard
Responsibility
Bernard Swynghedauw
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2019
Physical Description
1 online resource (xi, 121 p.) : 23 illus., 13 illus. in color
Series Title
Practical issues in geriatrics
ISBN
9783030151119
9783030151102 (Print ed.)
9783030151126 (Print ed.)
9783030151133 (Print ed.)
ISSN
2509-6060
Subjects (MeSH)
Aging - physiology
Cellular Senescence - physiology
Geriatrics
Specialty
Geriatrics
Physiology
Abstract
This book describes the fundamental process of senescence, and reviews a new concept developed by a number of research groups that is based on cellular senescence and its secretome. This concept provides a basic explanation of the main physiological and pathological features of senescence, and delineates possibilities for “treating” it. Following an introduction to the emerging medical landscape, the increasing incidence of a new epidemiological group (age-related “chronic non-transmissible diseases”), and the multiple origins of aging, the book explores and characterizes the senescent cell, which is linked to benign and pathological age-related manifestations. In turn, the closing chapters discuss how to “treat” or “prevent” the aging process, underscoring the central role of physical exercise and caloric reduction as compared to new senolytic approaches. Appendices are also provided, and address circadian rhythms, telomere shortening, diabetic cardiomyopathy, and senescence in plants and bacteria. Given its scope, the book will primarily be of interest to geriatricians, but will also appeal to a wider range of clinicians.
Contents
1. Introduction -- 2. The emerging medical landscape -- 3. Origins of ageing -- 4. The senescent cell, SC-- 5. The nonfatal clinical manifestations of ageing -- 6. Age-linked non-transmissible diseases -- 7. How to treat or prevent, or slow down, cellular ageing and senescence? -- 8. Senescence: a Darwinian evolutionary perspective -- 9. Conclusion -- 10. Summary -- Annex A: Senescence in Plants and Bacteria -- Annex B: Theories of Ageing -- Annex C: Telomeres and Telomerase -- Annex D: MicroRNAs, miRs -- Annex E: Circadian Rhythms, a Fundamental Basis of Life -- Annex F: The Diabetic Heart -- Glossary.
Format
e-Book
Location
Online
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Centenarians : An Example of Positive Biology

https://libcat.nshealth.ca/en/permalink/provcat44369
Calogero Caruso, editor. --Cham: Springer , c2019.
Available Online
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Location
Online
This state-of-the-art review on longevity focuses on centenarians, studied as a model of positive biology. The extraordinary rise in the elderly population in developed countries underscores the importance of studies on ageing and longevity in order to decrease the medical, economic and social problems associated with the increased number of non-autonomous individuals affected by invalidating pathologies. Centenarians have reached the extreme limits of human life span. Those in relatively good …
Available Online
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Other Authors
Caruso, Calogero
Responsibility
Calogero Caruso, editor
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2019
Physical Description
1 online resource (vii, 179 p.) : 13 illus., 11 illus. in color
ISBN
9783030207625
9783030207618 (Print ed.)
9783030207632 (Print ed.)
9783030207649 (Print ed.)
Subjects (MeSH)
Aged, 80 and over
Aging - physiology
Geriatrics
Longevity
Specialty
Geriatrics
Abstract
This state-of-the-art review on longevity focuses on centenarians, studied as a model of positive biology. The extraordinary rise in the elderly population in developed countries underscores the importance of studies on ageing and longevity in order to decrease the medical, economic and social problems associated with the increased number of non-autonomous individuals affected by invalidating pathologies. Centenarians have reached the extreme limits of human life span. Those in relatively good health, who are able to perform their routine daily tasks, are the best examples of extreme longevity, representing selected individuals in which the appearance of major age-related diseases – including cancer and cardiovascular diseases – has been consistently delayed or avoided. The relationship between causality and chance is an open discussion topic in many disciplines. In particular, ageing, the related diseases, and longevity are difficult to define as a consequence of causality, chance or both. Discussing the relevance of these different factors in the attainment of longevity, the book gathers contributions on genetic, epigenetic and phenotypic aspects of centenarians. The “positive biology” approach is applied to clarify the causes of positive phenotypes, as well as to explain the biological mechanisms of health and well-being with the aim of preventing and/or reducing frailty and disability in the elderly.
Contents
1. Chance and Causality in Ageing and Longevity -- 2. Phenotypic Aspects of Longevity -- 3. Centenarian Offspring as a Model of Successful Ageing -- 4. Individual Longevity Versus Population Longevity -- 5. Dietary Inflammatory Index in Ageing and Longevity -- 6. Genetic Signatures of Centenarians -- 7. Epigenetics and Ageing -- 8. Lifestyle Choices, Psychological Stress, and Their Impact on Aging: The Role of Telomeres -- 9. Gut Microbiota Pattern of Centenarians -- 10. The Impact of Mediterranean Diet on Longevity -- 11. Lifespan and Healthspan Extension by Nutraceuticals: An Overview.
Format
e-Book
Location
Online
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Clinical neurology of aging

https://libcat.nshealth.ca/en/permalink/provcat33481
edited by Martin L. Albert, Janice E. Knoefel. (3rd ed.) --New York: Oxford University Press , 2011.
Available Online
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Location
Online
This resource features 60 chapters written by the world's elite clinicians from neurology, geriatrics and research on all aspects of geriatric neurology, and the authors have incorporated the geriatric care perspective and a quality-oriented approach to health care throughout, resulting in the definitive reference for all clinicians caring for older people as well as for those who set policies that affect research and clinical practice.
Available Online
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Other Authors
Albert, Martin L., 1939-
Knoefel, Janice E.
Responsibility
edited by Martin L. Albert, Janice E. Knoefel
Edition
3rd ed.
Place of Publication
New York
Publisher
Oxford University Press
Date of Publication
2011
Physical Description
1 online resource (xix, 641 p.)
ISBN
9780199323012 (eISBN)
9780195369298
Subjects (MeSH)
Aging - physiology
Nervous System Diseases
Nervous System Physiological Phenomena
Subjects (LCSH)
Geriatric neurology
Abstract
This resource features 60 chapters written by the world's elite clinicians from neurology, geriatrics and research on all aspects of geriatric neurology, and the authors have incorporated the geriatric care perspective and a quality-oriented approach to health care throughout, resulting in the definitive reference for all clinicians caring for older people as well as for those who set policies that affect research and clinical practice.
Contents
Introduction to Geriatric Neurology -- 1. Geriatric Neurology—An Introduction -- 2. Epidemiology of Aging and Age-related Neurological Disease -- 3. Neurogenetics of Aging4 Special Aspects of Research in Aging -- Neurological Assessment in Aging -- 5. Neurological Evaluation of the Elderly Patient -- 6. Mental Status Examination in the Elderly -- 7. The Process of Geriatric Neuropsychological Assessment -- 8. Anatomical Neuroimaging in Aging -- 9. Functional Neuroimaging in Aging -- 10. Electroencephalography and Evoked Potentials in Geriatrics -- 11. Nerve Conduction Studies and Electromyography -- 12. Competency, Capacity, and Self-determination in Aging -- 13. Functional Assessment in Geriatric Neurology -- Cognitive Disorders in Aging -- 14. Cognitive Function in Healthy Aging -- 15. Mild Cognitive Impairment -- 16. Alzheimer’s Disease -- 17. Frontotemporal Dementia and Related Syndromes -- 18. Vascular Cognitive Impairment -- 19. Synucleinopathies -- 20. Alcohol and Toxin-related Dementias -- 21. Delirium in the Elderly -- Motor Disorders in Aging -- 22. Parkinson’s Disease -- 23. Other Parkinsonian Disorders -- 24. Essential Tremor -- 25. Gait Disturbances in Aging -- 26. Falls in Aging and Neurological Disease -- 27. The Ataxias -- 28. Dyskinetic Movement Disorders -- 29. Simple and Complex Sleep-related Movement Disorders in Older Adults -- Sensory Disturbance in Aging -- 30. Neuro-ophthalmology of the Afferent Visual System in Aging -- 31. The Aging Auditory System -- 32. Dizziness in the Elderly -- 33. Taste and Smell in Aging -- 34. Autonomic Dysfunction in the Elderly -- Peripheral Neurology in Aging -- 35. Spinal Disorders in the Elderly -- 36. Motor Neuron Disease -- 37. Primary and Inflammatory Muscle Disorders in the Elderly -- 38. Peripheral Motor and Sensory Neuropathies in Aging -- Disease States in the Elderly -- 39. Stroke -- 40. Epilepsy and the Elderly -- 41. Head Injury in the Elderly -- 42. Language Changes Associated with Aging -- 43. Normal Pressure Hydrocephalus -- 44. Spinal Cord Injury and Dysfunction in the Elderly -- 45. Brain Tumor in the Elderly -- 46. Multiple Sclerosis in the Elderly -- 47. Sleep Disorders in Aging -- 48. Headache in the Elderly -- 49. Shingles and Postherpetic Neuralgia in the Elderly -- Neurological Therapeutics -- 50. Neurorehabilitation in the Elderly -- 51. Pain Management in the Elderly -- 52. Pharmacotherapy Considerations in Geriatric Neurology -- 53. Cognitive Enhancement in the Elderly -- 54. Cognitive and Physical Benefits of Exercise in the Aging -- 55. Palliative Care and Neurological Illness: An Approach to Long-term Neurological Conditions and Catastrophic Illness.
Format
e-Book
Location
Online
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Communication and swallowing changes in healthy aging adults

https://libcat.nshealth.ca/en/permalink/provcat24904
Burda, Angela N. --Sudbury, MA: Jones and Bartlett , 2011.
Call Number
WT 104 B949c 2011
Location
Dickson Building
Call Number
WT 104 B949c 2011
Author
Burda, Angela N
Place of Publication
Sudbury, MA
Publisher
Jones and Bartlett
Date of Publication
2011
Physical Description
194 p.
ISBN
9780763776565
Subjects (MeSH)
Aging - physiology
Communication - Aged
Deglutition - Aged
Geriatric Assessment
Format
Book
Location
Dickson Building
Loan Period
3 weeks
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Diabetes and Aging-related Complications

https://libcat.nshealth.ca/en/permalink/provcat43238
Sho-ichi Yamagishi, editor. --Singapore: Springer , c2018.
Available Online
View e-Book
Location
Online
This book addresses why and how the aging process is accelerated under diabetes, providing valuable and comprehensive information for the management of various types of diabetes- and aging-related disorders. Since several papers have shown that average life span and healthy life expectancy are reduced in diabetic patients, especially in those with a long history of disease, the early detection and treatment of diabetes-related complications are urgently needed in order to slow the aging process…
Available Online
View e-Book
Other Authors
Yamagishi, Sho-ichi
Responsibility
Sho-ichi Yamagishi, editor
Place of Publication
Singapore
Publisher
Springer
Date of Publication
c2018
Physical Description
1 online resource (viii, 212 p.) : 57 illus., 32 illus. in color
ISBN
9789811043765
9789811043758 (print ed.)
9789811043772 (print ed.)
Subjects (MeSH)
Age Factors
Aging - physiology
Diabetes Complications
Diabetes Mellitus
Specialty
Diabetes Mellitus
Geriatrics
Abstract
This book addresses why and how the aging process is accelerated under diabetes, providing valuable and comprehensive information for the management of various types of diabetes- and aging-related disorders. Since several papers have shown that average life span and healthy life expectancy are reduced in diabetic patients, especially in those with a long history of disease, the early detection and treatment of diabetes-related complications are urgently needed in order to slow the aging process and help people successfully live with diabetes. Each chapter of this book addresses a specific diabetes and aging-related complication. The topics covered include not only diabetic vascular complications, the leading causes of morbidities and high mortality rates in both type 1 and type 2 diabetic patients, but also other aging-related complications such as Alzheimer's disease, osteoporosis, periodontitis and cancer growth and metastasis. Experts on each topic discuss the background of the aging process and methods for coping with diabetes-related complications. The book as a whole, as well as the individual chapters, offer a valuable resource for researchers and practitioners in the fields of diabetic studies, gerontology, and aging science.
Contents
1. Diabetic Nephropathy -- 2. Diabetic Eye Disease -- 3. Diabetic Neuropathy -- 4. Diabetes and Endothelial Dysfunction -- 5. Diabetes and Vascular Calcification -- 6. Diabetes and Adipocyte Dysfunction -- 7. Diabetes and Liver Disorders -- 8. Diabetes and Alzheimer's Disease -- 9. Diabetes and Cancers -- 10. Diabetes and Osteoporosis -- 11. Diabetes and Sarcopenia -- 12. Diabetes and Frailty -- 13. Diabetes and LOH Syndrome -- 14. Diabetes and Female Sterility/Infertility -- 15. Diabetes and Periodontitis -- 16. Diabetes and Advanced Glycation End Products.
Format
e-Book
Location
Online
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Dietary Patterns and Whole Plant Foods in Aging and Disease

https://libcat.nshealth.ca/en/permalink/provcat43277
Mark L. Dreher. --Cham: Humana Press , c2018.
Available Online
View e-Book
Location
Online
This text provides a comprehensive review of the latest research on the effects of dietary patterns and whole plant foods on general health, aging, and cardiometabolic disease risk from major prospective cohort studies and randomized controlled trials (RCTs) and their meta-analyses. The book extensively assesses the effects of lifestyle, dietary patterns, and specific whole plant foods on the quality of aging; the impact of fiber-rich foods on colonic microbiotia and weight regulation, the effe…
Available Online
View e-Book
Author
Dreher, Mark L.
Responsibility
Mark L. Dreher
Place of Publication
Cham
Publisher
Humana Press
Date of Publication
c2018
Physical Description
1 online resource (xxviii, 619 p.) : 225 illus., 204 illus. in color
Series
Nutrition and Health
Series Title
Nutrition and health (Totowa, N.J.)
ISBN
9783319591803
9783319591797 (print ed.)
9783319591810 (print ed.)
Subjects (MeSH)
Aging - physiology
Chronic Disease - prevention & control
Feeding Behavior
Healthy Aging - physiology
Healthy Diet
Plants, Edible - physiology
Specialty
Nutritional Sciences
Abstract
This text provides a comprehensive review of the latest research on the effects of dietary patterns and whole plant foods on general health, aging, and cardiometabolic disease risk from major prospective cohort studies and randomized controlled trials (RCTs) and their meta-analyses. The book extensively assesses the effects of lifestyle, dietary patterns, and specific whole plant foods on the quality of aging; the impact of fiber-rich foods on colonic microbiotia and weight regulation, the effects of which influence the quality of aging; the effects of fiber-rich diets on the aging gastrointestinal tract; and the role of dietary patterns and specific whole plant foods on coronary heart disease, hypertension, chronic kidney disease, stroke and type 2 diabetes. Figures are extensively used to highlight findings and tables summarizing food composition dietary patterns and whole plant foods. Tables summarizing meta-analyses and representative cohort studies and RCTs provide state-of-the-art coverage of the important effect of dietary patterns and whole plant foods on aging and cardiometabolic diseases. Dietary Patterns and Whole Plant Foods in Aging and Disease will serve as a very useful, state -of -the-art resource for dietitians, physicians, nurses, food industry scientists, researchers, naturopathic doctors, educators and their students interested in the role of dietary patterns and specific whole plant foods on aging and disease.
Contents
Part I. Overview of Aging and Disease -- 1. Major Lifestyles and Phenotypes in Aging and Disease -- 2. Dietary Patterns in Aging and Disease -- 3. Whole Plant Foods in Aging and Disease -- Part II. Gastrointestinal Tract -- 4. Fiber-Rich Dietary Patterns and Colonic Microbiota in Aging and Disease -- 5. Fiber-Rich Dietary Patterns and Foods in Laxation and Constipation -- 6. Dietary Patterns, Foods and Fiber in Irritable Bowel Syndrome and Diverticular Disease -- Part III. Weight Management and Related Diseases -- 7 Dietary Patterns and Fiber in Body Weight and Composition Regulation -- 8. Whole Plant Foods in Body Weight and Composition Regulation -- 9. Dietary Patterns and Whole Plant Foods in Type 2 Diabetes Prevention and Management -- 10. Dietary Patterns, Foods, Nutrients and Phytochemicals in Non-Alcoholic Fatty Liver Disease -- Part IV. Cardiovascular and Cerebrovascular Diseases, and Age-Related Cognitive Function -- 11. Dietary Patterns and Coronary Heart Disease -- 12. Whole Plant Foods and Coronary Heart Disease -- 13. Dietary Patterns and Hypertension -- 14. Whole Plant Foods and Hypertension -- 15. Dietary Patterns, Foods and Beverages in Chronic Kidney Disease -- 16. Dietary Patterns and Stroke Risk -- 17. Whole Plant Foods and Stroke Risk -- 18. Dietary Patterns, Foods and Beverages in Age-Related Cognitive Performance and Dementia -- Part V. Cancer Prevention and Survival -- 19. Dietary Patterns, Whole Plant Foods, Nutrients and Phytochemicals in Colorectal Cancer Prevention and Management -- 20. Dietary Patterns, Whole Plant Foods, Nutrients and Phytochemicals in Breast Cancer Prevention and Management.
Format
e-Book
Location
Online
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Dr. Atkins' age defying diet

https://libcat.nshealth.ca/en/permalink/provcat20753
Atkins, Robert C. --New York, NY: St. Martin's Press , 2001.
Call Number
WD 210 At53D 2001
Location
Nova Scotia Hospital
Call Number
WD 210 At53D 2001
Author
Atkins, Robert C
Place of Publication
New York, NY
Publisher
St. Martin's Press
Date of Publication
2001
ISBN
0312977018
Subjects (MeSH)
Diet
Longevity
Aging - physiology
Format
Book
Location
Nova Scotia Hospital
Loan Period
3 weeks
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