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Combination therapy in hypertension

https://libcat.nshealth.ca/en/permalink/provcat33281
Joel M. Neutel. --London: Springer Healthcare , c2011.
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Location
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For over 30 years, the stepped care approach has been used in the management and treatment of hypertension. This approach advocates the use of initial monotherapy to reach the desired blood pressure, and the subsequent use of additional drugs with complementary modes of action, until the target BP is achieved. However, current control rates for hypertension suggest that such an approach may be outdated and no longer effective in the management of hypertension. Clinical trials have shown that mo…
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Author
Neutel, Joel M
Responsibility
Joel M. Neutel
Place of Publication
London
Publisher
Springer Healthcare
Date of Publication
c2011
Physical Description
1 online resource (vii, 84 pages)
ISBN
9781908517289 (electronic bk.)
9781908517258
Subjects (MeSH)
Hypertension - therapy
Antihypertensive Agents - therapeutic use
Subjects (LCSH)
Cardiology
Pharmacotherapy
Primary Care Medicine
Angiology
General Practice / Family Medicine
Hypertension - Treatment
M├ędecine
Abstract
For over 30 years, the stepped care approach has been used in the management and treatment of hypertension. This approach advocates the use of initial monotherapy to reach the desired blood pressure, and the subsequent use of additional drugs with complementary modes of action, until the target BP is achieved. However, current control rates for hypertension suggest that such an approach may be outdated and no longer effective in the management of hypertension. Clinical trials have shown that more than 50% of patients require a combination of drug therapies to achieve their target BP. Some proponents of combination therapy have argued that the risk of adverse side effects and non-compliance will be lower than that compared to monotherapy, which initially requires higher doses to be administered to be effective. Consequently, there have been increasing calls of the necessity for a much more combined approach in the treatment of hypertension. Adding to this, Combination Therapy in Hypertension will cover current control rates of blood pressure worldwide, the benefits of monotherapy and combination therapy, examine the effectiveness, risk of adverse effects, compliance, and cost of the available therapies and will also include information on relevant outcome studies.
Contents
State of Hypertension Control -- Historical Review of Combination Therapy -- Advantages of Combination Therapy Compared with Monotherapy -- Use of Combination Therapy in Special Populations -- The Evidence Base for Combination Therapy -- Combination Therapy as First-Line Treatment -- Future Combination Agents -- Clinical Inertia in the Management of Hypertension.
Format
e-Book
Location
Online
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Duplex ultrasound of superficial leg veins

https://libcat.nshealth.ca/en/permalink/provcat33861
Erika Mendoza, Christopher R. Lattimer, Nick Morrison, editors. --Heidelberg: Springer , c2014.
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Location
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This book describes in detail the use of duplex ultrasound for exploration of the superficial veins and their pathology. It has a practical orientation, presenting numerous clinical situations and explaining how to identify the different sources of reflux, specially in the groin. The investigation of pathology of the saphenous trunks, perforators, and side branches is described in detail. As duplex ultrasound plays an important role during various venous surgical procedures, its application pre…
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Other Authors
Mendoza, Erika
Lattimer, C. R.
Morrison, Nick
Responsibility
Erika Mendoza, Christopher R. Lattimer, Nick Morrison, editors
Place of Publication
Heidelberg
Publisher
Springer
Date of Publication
c2014
Physical Description
1 online resource (xiii, 332 pages)
ISBN
9783642407314 (electronic bk.)
9783642407307
Subjects (MeSH)
Leg - blood supply
Ultrasonography
Ultrasonography, Doppler, Duplex - methods
Veins - diagnostic imaging
Subjects (LCSH)
Veins - Ultrasonic imaging
Veins - Diseases - Ultrasonic imaging
Ultrasound
Vascular Surgery
Angiology
Abstract
This book describes in detail the use of duplex ultrasound for exploration of the superficial veins and their pathology. It has a practical orientation, presenting numerous clinical situations and explaining how to identify the different sources of reflux, specially in the groin. The investigation of pathology of the saphenous trunks, perforators, and side branches is described in detail. As duplex ultrasound plays an important role during various venous surgical procedures, its application pre-, intra-, and postoperatively is presented. Furthermore, the sonographic appearances of thrombotic pathology of superficial and deep veins, edema, and other conditions that may be observed while exploring the veins are fully described. The book is based on the authors' extensive clinical experience and is intended to assist fellow practitioners who want to learn more about the technique. It includes a wealth of informative images with the aim of covering every potential situation.
Contents
The Ultrasound Scanner -- Anatomy of the Superficial Veins -- Pathophysiology of the Superficial Venous System -- Ultrasound-Based Classifications of Varicose Veins -- Duplex Ultrasound Examination of Superficial Leg Veins -- Flow Provocation Manoeuvres for the Diagnosis of Venous Disease Using Duplex Ultrasound -- Examination of the Great Saphenous Vein -- Examination of the Small Saphenous Vein -- Perforating Veins -- Tributaries -- Superficial Vein Thrombosis -- Ultrasound in Varicose Vein Treatment -- Ultrasound After Venous Intervention -- Deep Leg Veins -- Examination of Superficial Veins in the Presence of Deep Venous Disease -- Differential Diagnosis of Leg Oedemas of Venous and Lymphatic Origin -- Incidental Findings During a Venous Examination of the Leg.
Format
e-Book
Location
Online
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