Antibiotics as Anti-Inflammatory and Immunomodulatory Agents
https://libcat.nshealth.ca/en/permalink/provcat29686
edited by Bruce K. Rubin, Jun Tamaoki.
--Basel:
Birkhäuser Verlag
, c2005.
- Available Online
- View e-Book
- Location
- Online
- Available Online
- View e-Book
- Author
- Rubin, Bruce K
- Other Authors
- Tamaoki, Jun
- Responsibility
- edited by Bruce K. Rubin, Jun Tamaoki
- Place of Publication
- Basel
- Publisher
- Birkhäuser Verlag
- Date of Publication
- c2005
- Series Title
- Progress in inflammation research
- ISBN
- 9783764373108
- Subjects (MeSH)
- Anti-Bacterial Agents - therapeutic use
- Anti-Inflammatory Agents - therapeutic use
- Immunomodulation
- Subjects (LCSH)
- Pharmacy
- Immunology
- Format
- e-Book
- Location
- Online
Clinical Manual of Fever in Children
https://libcat.nshealth.ca/en/permalink/provcat30372
edited by A. Sahib El-Radhi, James Carroll, Nigel Klein.
--Berlin, Heidelberg:
Springer
, c2009.
- Available Online
- View e-Book
- Location
- Online
- Available Online
- View e-Book
- Author
- El-Radhi, A. Sahib
- Other Authors
- Carroll, James
- Klein, Nigel
- Responsibility
- edited by A. Sahib El-Radhi, James Carroll, Nigel Klein
- Place of Publication
- Berlin, Heidelberg
- Publisher
- Springer
- Date of Publication
- c2009
- ISBN
- 9783540785989
- Subjects (MeSH)
- Anti-Inflammatory Agents - therapeutic use - Child
- Fever - physiopathology - Child
- Fever - therapy - Child
- Subjects (LCSH)
- Pediatrics
- Format
- e-Book
- Location
- Online
Inflammatory Arthritis in Clinical Practice
https://libcat.nshealth.ca/en/permalink/provcat38905
Ian C. Scott, James B. Galloway, David L. Scott.
(2nd ed.)
--London:
Springer
, c2015.
- Available Online
- View e-Book
- Location
- Online
This evidence based book covers the key components in the diagnosis, assessment and management of inflammatory arthritis. The authors look at the epidemiology, pathology, clinical assessment and investigation of inflammatory arthritis patients, and provide an overview of currently available treatment options. With major changes seen in the way inflammatory arthropathies are diagnosed, classified, investigated and managed, Inflammatory Arthritis in Clinical Practice, Second Edition provides the …
- Available Online
- View e-Book
- Author
- Scott, Ian C
- Other Authors
- Galloway, James B
- Scott, David L
- Responsibility
- Ian C. Scott, James B. Galloway, David L. Scott
- Edition
- 2nd ed.
- Place of Publication
- London
- Publisher
- Springer
- Date of Publication
- c2015
- Physical Description
- 1 online resource (xviii, 214 p. : 36 illus., 27 illus. in color)
- ISBN
- 9781447166481
- 9781447166474 (print ed.)
- Subjects (MeSH)
- Anti-Inflammatory Agents - therapeutic use
- Antirheumatic Agents - therapeutic use
- Arthritis, Rheumatoid - drug therapy
- Inflammation - drug therapy
- Spondylarthritis - drug therapy
- Abstract
- This evidence based book covers the key components in the diagnosis, assessment and management of inflammatory arthritis. The authors look at the epidemiology, pathology, clinical assessment and investigation of inflammatory arthritis patients, and provide an overview of currently available treatment options. With major changes seen in the way inflammatory arthropathies are diagnosed, classified, investigated and managed, Inflammatory Arthritis in Clinical Practice, Second Edition provides the reader with the most up-to-date developments in this area.
- Contents
- 1. An Overview of Inflammatory Arthritis -- 2. Epidemiology and Pathology -- 3. Clinical Features -- 4. Clinical and Laboratory Assessments -- 5. Symptomatic Drug Treatment -- 6. Disease-Modifying Anti-Rheumatic Drugs -- 7. Biologics: An Overview -- 8. Anti-Tumour Necrosis Factor-Alpha (TNF-) Treatment -- 9. B Cell Inhibition and other Biologics -- 10. Steroids -- 11. Non-Drug Treatments -- 12. Stopping Treatments -- 13. Emerging Therapies in Rheumatoid Arthritis -- 14. Stratified Medicine in Inflammatory Arthritis.
- Format
- e-Book
- Location
- Online
Prospects for chemoprevention of colorectal neoplasia : emerging role of anti-inflammatory drugs
https://libcat.nshealth.ca/en/permalink/provcat32505
Andrew T. Chan, Elmar Detering, editors.
--Berlin, Heidelberg:
Springer
, c2013.
- Available Online
- View e-Book
- Location
- Online
The prevention of colorectal cancer is a subject of increasing medical importance, and there have been a number of promising recent developments. This book examines in detail important aspects of the current status and future prospects for chemoprevention of colorectal tumors. Research into the mechanisms that lead from early colorectal adenoma to colorectal cancer is discussed. The role and modes of action of available drugs such as celecoxib and sulindac are described, and recent data from a…
- Available Online
- View e-Book
- Other Authors
- Chan, Andrew T
- Detering, Elmar
- Responsibility
- Andrew T. Chan, Elmar Detering, editors
- Place of Publication
- Berlin, Heidelberg
- Publisher
- Springer
- Date of Publication
- c2013
- Physical Description
- 1 online resource (viii, 183 p. : 29 ill., 18 ill. in color)
- Series Vol.
- 191
- Series Title
- Recent results in cancer research
- ISBN
- 9783642303319
- Subjects (MeSH)
- Anti-Inflammatory Agents - therapeutic use
- Chemoprevention
- Colorectal Neoplasms - prevention & control
- Precancerous Conditions - drug therapy
- Subjects (LCSH)
- Internal medicine
- Cardiology
- Gastroenterology
- Oncology
- Colon (Anatomy) - Surgery
- Abstract
- The prevention of colorectal cancer is a subject of increasing medical importance, and there have been a number of promising recent developments. This book examines in detail important aspects of the current status and future prospects for chemoprevention of colorectal tumors. Research into the mechanisms that lead from early colorectal adenoma to colorectal cancer is discussed. The role and modes of action of available drugs such as celecoxib and sulindac are described, and recent data from aspirin trials are analyzed. In addition, the possible impact of nutritional agents with anti-inflammatory properties is considered, and strategies applicable in those with a high level of genetic risk are evaluated. An important feature of the book is its holistic perspective, making it relevant for gastroenterologists, internists, general practitioners, oncologists, colorectal and gastroenterological surgeons, and public health practitioners.
- Contents
- What is chemoprevention today?- Mechanistic aspects in tumor development and progression of colorectal adenoma and carcinoma -- Mode of action of aspirin as a chemopreventive agent -- Coxibs: pharmacology, toxicity and efficacy in cancer clinical trials -- COX-2 active agents in chemoprevention (includes aspirin, coxibs, and DFMO) -- New potential developments in aspirin/NSAID derivatives -- Aspirin in CRC chemoprevention in the context of other chronic diseases -- Nutritional agents with anti-inflammatory properties in chemoprevention of colorectal adenoma and carcinoma -- Genetic risks for CRC and hereditary forms of CRC. Strategies for prevention in high risk population -- References.
- Format
- e-Book
- Location
- Online
Targeting the IL-17 Pathway in Inflammatory Disorders
https://libcat.nshealth.ca/en/permalink/provcat41287
Cong-Qiu Chu.
--Cham:
Adis
, 2017.
- Available Online
- View e-Book
- Location
- Online
This book provides an overview of the discovery and structure of IL-17, including its pathogenesis and role in chronic inflammation and autoimmunity. To capture the latest developments and product approvals the book also discusses the therapeutic advances and looks at emerging therapies targeting the IL-17 pathway. IL-17 is a pro-inflammatory cytokine that has a key role in inflammation, autoimmunity, and host defense in a number of inflammatory disorders such as rheumatoid arthritis, psoriatic…
- Available Online
- View e-Book
- Author
- Chu, Cong-Qiu
- Responsibility
- Cong-Qiu Chu
- Place of Publication
- Cham
- Publisher
- Adis
- Date of Publication
- 2017
- Physical Description
- 1 online resource (xv, 102 pages) : 6 illus. in color
- ISBN
- 9783319280400
- 9783319280394 (print ed.)
- Subjects (MeSH)
- Anti-Inflammatory Agents - therapeutic use
- Drug Delivery Systems
- Inflammation - drug therapy
- Interleukin-17 - immunology
- Interleukin-17- antagonists & inhibitors
- Th17 Cells - chemistry
- Abstract
- This book provides an overview of the discovery and structure of IL-17, including its pathogenesis and role in chronic inflammation and autoimmunity. To capture the latest developments and product approvals the book also discusses the therapeutic advances and looks at emerging therapies targeting the IL-17 pathway. IL-17 is a pro-inflammatory cytokine that has a key role in inflammation, autoimmunity, and host defense in a number of inflammatory disorders such as rheumatoid arthritis, psoriatic arthritis and psoriasis, ankylosing spondylitis, multiple sclerosis, and inflammatory bowel disease. The discovery of the IL-17-Th17 pathway has seen exciting development in the field of immunology and inflammation research, which has led to a number of recent regulatory approvals.
- Contents
- 1. Overview of the IL-17 Family -- 2. IL-17 in Host Defense -- 3. Th17 Cells: Differentiation and Regulation -- 4. The Role of IL-17/Th17 Pathway in the Pathogenesis of Autoimmune Inflammatory Diseases -- 5. Therapeutic Applications: Strategies and Molecules Targeting the IL-17/Th17 Pathway -- 6. Concluding Remarks
- Format
- e-Book
- Location
- Online
Treatment of Inflammatory Bowel Disease with Biologics
https://libcat.nshealth.ca/en/permalink/provcat42935
edited by Adam S. Cheifetz, Joseph D. Feuerstein.
--Cham, Switzerland:
Springer
, c2018.
- Available Online
- View e-Book
- Location
- Online
This book is a concise yet comprehensive overview of the use of biologics for the treatment of Crohn's disease and ulcerative colitis. The volume details how best to utilize these medications in order to optimize their efficacy and safety, as well as how to understand, recognize, and treat complications that may arise from using biologics to treat IBD. The text also focuses on new data, novel biologics, and biosimilars of this rapidly expanding field. Written by experts in the field, Treatment …
- Available Online
- View e-Book
- Other Authors
- Cheifetz, Adam S.
- Feuerstein, Joseph D.
- Responsibility
- edited by Adam S. Cheifetz, Joseph D. Feuerstein
- Place of Publication
- Cham, Switzerland
- Publisher
- Springer
- Date of Publication
- c2018
- Physical Description
- 1 online resource (xi, 335 p.) : 22 illus., 19 illus. in color
- ISBN
- 9783319602769
- 9783319602752 (print ed.)
- 9783319602776 (print ed.)
- 9783319868233 (print ed.)
- Subjects (MeSH)
- Anti-Inflammatory Agents - therapeutic use
- Biological Products - therapeutic use
- Inflammatory Bowel Diseases - drug therapy
- Specialty
- Biological Therapy
- Gastroenterology
- Abstract
- This book is a concise yet comprehensive overview of the use of biologics for the treatment of Crohn's disease and ulcerative colitis. The volume details how best to utilize these medications in order to optimize their efficacy and safety, as well as how to understand, recognize, and treat complications that may arise from using biologics to treat IBD. The text also focuses on new data, novel biologics, and biosimilars of this rapidly expanding field. Written by experts in the field, Treatment of Inflammatory Bowel Disease with Biologics is a valuable resource for gastroenterologists, allied health professionals, fellows, and trainees who treat patients with inflammatory bowel disease.
- Contents
- Mechanism of Action and Pharmacokinetics of Biologics -- Anti-tumor Necrosis Factor Agents in Ulcerative Colitis -- Anti-tumor Necrosis Factor Agents in Crohn's Disease -- Anti-TNF Therapy for Treatment of Extraintestinal Manifestations of Inflammatory Bowel Disease -- Use of Biologics in the Postoperative Management of Crohn's Disease -- Biologics in Pregnancy and Breastfeeding -- Concomitant Use of Immunosuppressive Therapy with Tumor Necrosis Factor (TNF) Antagonists in Inflammatory Bowel Disease -- Therapeutic Drug Monitoring of Biologic Agents -- Use of Biologics in Crohn's Disease and Ulcerative Colitis Prior to Surgery and Perioperative Risks -- Cessation of Biologics—Can it be Done? -- Biologic Therapy in Pediatric Inflammatory Bowel Disease -- Infectious Complications of Biologics -- Tumor Necrosis Factor-Alpha Inhibitors and Risks of Malignancy -- Non-infectious and Non-malignant Complications of Biologics -- Biosimilars in Inflammatory Bowel Disease 2017: State of the Science, State of the Art, State of the Finances -- Anti-Integrin Agents in IBD: Efficacy and Risk of Complications -- Novel Agents in Inflammatory Bowel Disease -- Quality, Safety, and Practical Considerations of Using Biologic Therapies.
- Format
- e-Book
- Location
- Online
Treatment of Non-Infectious Uveitis
https://libcat.nshealth.ca/en/permalink/provcat44746
Phoebe Lin, Eric Suhler, editors.
--Cham:
Springer
, c2019.
- Available Online
- View e-Book
- Location
- Online
This unique, comprehensive book provides a much-needed reference on the treatment and management of non-infectious uveitis. Carefully designed, Treatment of Non-infectious Uveitis is the first book of its kind to provide an in-depth, clinically-relevant, expert-driven resource for ophthalmologists focusing on modalities of uveitis treatment, their mechanism of action, dosing, and side effects. Each chapter provides an introduction, mechanism of action, indication, dosage, side effects, and effi…
- Available Online
- View e-Book
- Other Authors
- Lin, Phoebe
- Suhler, Eric
- Responsibility
- Phoebe Lin, Eric Suhler, editors
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2019
- Physical Description
- 1 online resource (xii, 205 p.) : 28 illus., 19 illus. in color
- ISBN
- 9783030228279
- 9783030228255 (Print ed.)
- 9783030228262 (Print ed.)
- Subjects (MeSH)
- Adrenal Cortex Hormones - therapeutic use
- Anti-Inflammatory Agents - therapeutic use
- Antimetabolites - therapeutic use
- Uveitis - drug therapy
- Specialty
- Ophthalmology
- Abstract
- This unique, comprehensive book provides a much-needed reference on the treatment and management of non-infectious uveitis. Carefully designed, Treatment of Non-infectious Uveitis is the first book of its kind to provide an in-depth, clinically-relevant, expert-driven resource for ophthalmologists focusing on modalities of uveitis treatment, their mechanism of action, dosing, and side effects. Each chapter provides an introduction, mechanism of action, indication, dosage, side effects, and efficacy summaries from clinical trials and other published literature. Topics range from topical treatment, to locally administered therapy including drug-releasing implants, to systemic immunosuppressive treatments both tried and new, as well as surgical management, with each chapter highlighting important practice pearls as well as easy-reference dosing tables, side effects, and lab monitoring pertinent to the agents discussed. The book concludes with a discussion of novel approaches to the treatment of non-infectious uveitis, and special considerations when treating uveitis in the pediatric patient. The majority of patients with non-infectious uveitis are treated by comprehensive ophthalmologists, many of whom are less familiar with established treatment guidelines outlining the role of corticosteroids and immunomodulatory therapy. While the non-specialist, resident, or fellow is sure to benefit from this one-stop guide to uveitis treatment, retina and uveitis specialists alike will also appreciate the practice tips and thorough coverage of this expertly-written reference. Treatment of Non-infectious Uveitis is the ideal reference for all ophthalmologists who seek to improve their understanding of the causes of uveitis and learn how to best treat this condition.
- Contents
- 1. Introduction -- 2. Topical Therapy in Uveitis -- 3. Systemic Corticosteroids in the Treatment of Uveitis -- 4. Antimetabolites -- 5. T Cell Inhibitors -- 6. Alkylating Agents -- 7. Biologics Targeting Tumor Necrosis Factor -- 8. Biologics Targeting B and T Cell Activation -- 9. Targeting Interleukin-6 in Ocular Inflammatory Diseases -- 10. Interferons and Intravenous Immunoglobulin -- 11. Diagnostic Biopsies in the Management of Uveitis -- 12. Therapeutic Vitreoretinal Surgery for Non-infectious Intermediate, Posterior, and Panuveitis -- 13. Local Drug Delivery for Non-infectious Uveitis -- 14. Novel Approaches to the Treatment of Non-infectious Uveitis -- 15. Special Considerations: Treatment of Pediatric Uveitis.
- Format
- e-Book
- Location
- Online
