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Anticoagulation and Hemostasis in Neurosurgery

https://libcat.nshealth.ca/en/permalink/provcat40033
Christopher M. Loftus, editor. --Cham: Springer , c2016.
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This book is an up-to-date reference on all aspects of anticoagulation and hemostasis in neurosurgery. After an opening section on basic principles and drug classes in current use, detailed consideration is given to coagulation issues relevant to all patients, not just neurosurgical ones. The coverage includes, for example, deep vein thrombosis, pulmonary embolism, and disseminated intravascular coagulation. A variety of important issues specific to neurosurgical practice are then addressed, an…
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Other Authors
Loftus, Christopher M
Responsibility
Christopher M. Loftus, editor
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2016
Physical Description
1 online resource (xi, 404 p. : 61 illus., 43 illus. in color)
ISBN
9783319273273
9783319273259 (print ed.)
Subjects (MeSH)
Anticoagulants - therapeutic use
Blood Coagulation Disorders - therapy
Blood Coagulation - drug effects
Blood Loss, Surgical - prevention & control
Hemostasis, Surgical
Neurosurgical Procedures
Perioperative Care
Abstract
This book is an up-to-date reference on all aspects of anticoagulation and hemostasis in neurosurgery. After an opening section on basic principles and drug classes in current use, detailed consideration is given to coagulation issues relevant to all patients, not just neurosurgical ones. The coverage includes, for example, deep vein thrombosis, pulmonary embolism, and disseminated intravascular coagulation. A variety of important issues specific to neurosurgical practice are then addressed, and the book concludes with a summary of current guidelines and best practices. As the population ages and prophylactic anticoagulation for different cardiac disorders is validated by cooperative trials, it is becoming ever more important that practicing neurosurgeons have the requisite knowledge to manage optimally the opposing processes of anticoagulation and hemostasis. Nevertheless, only a modest amount of structured information is at present available on the subject, with the consequence that decision making is too often insufficiently informed. This book, written by recognized experts, is designed to rectify this situation by bringing together the latest knowledge from across the entire discipline. It will be of daily value for neurosurgeons and trainees worldwide and will also be of interest to emergency room physicians, surgeons in general, critical care physicians, neurologists, and hospital medicine specialists.
Contents
Part 1. General Principles -- Physiology of Hemostasis -- Laboratory Assessment of Physiologic and Pathologic Hemostasis -- Current Anticoagulation Drugs and Mechanisms of Action -- Reversal of Target-Specific Oral Anticoagulants -- Overview, Treatment, Measurement, and Modification of Platelet Function -- Role of Antiplatelet Therapy in Neurosurgery: Efficacy and Safety Profiles -- Part 2. Coagulation Issues Across all Patient Spectrums -- Congenital Coagulation Disorders -- Acquired Coagulation Disorders -- Regulation and Dysregulation of Fibrinolysis -- Risks Associated with Administration of Allogeneic Blood Components -- Common Coagulation Disorders That May Arise Intraoperatively -- Evaluation and Management of Untoward Intraoperative Bleeding -- Treatment of Disseminated Intravascular Coagulation (DIC) -- Heparin-Induced Thrombocytopenia (HIT) -- Anticoagulation in Cardiovascular Diseases -- Workup and Treatment of Pulmonary Embolus -- Part 3. Coagulation Issues Specific to Neurosurgery -- Classes of Drugs and Blood Products for Acute Reversal of Anticoagulant Effect -- Rescue Strategies to Facilitate Emergency Neurosurgery in Patients on Antiplatelet or Anticoagulant Agents -- Considerations for Coagulation in the Multi-Trauma Patient -- Cerebral Venous Sinus Thrombosis -- Coagulation Studies in Preoperative Neurosurgery Patients -- Safe Strategies for Gradual Suspension and Re-institution of Anticoagulation to Permit Elective Surgery -- Spontaneous Intracerebral Hemorrhage due to Coagulation Disorders -- Prophylactic Screening for Venous Thromboembolism in Neurosurgical Patients -- Venous Thromboembolism Prophylaxis in Neurosurgery -- Can Patients with Known Intracranial and Intraspinal Vascular Lesions be Anticoagulated? -- Intrathecal Access and Devices in Patients on Antiplatelet or Anticoagulant Therapy -- Is it Safe to Shunt Anti-coagulated NPH Patients? -- Surgical Hemostasis in the Era of Anticoagulation: Guidelines and Recommendations Summary.
Format
e-Book
Location
Online
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Anticoagulation Therapy

https://libcat.nshealth.ca/en/permalink/provcat42845
Joe F. Lau, Geoffrey D. Barnes, Michael B. Streiff, editors. --Cham: Springer , c2018.
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This book presents the latest evidence and guidelines supporting the use of anticoagulant therapy for various clinical scenarios. The field of anticoagulation therapy is evolving rapidly, particularly since the arrival and widespread adoption of direct oral anticoagulants. Organized in two parts, this book reviews the pharmacologic properties of various anticoagulants and details the clinical applications of anticoagulant therapy. Drugs such as warfarin and unfractionated heparin, as well as pa…
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Other Authors
Lau, Joe F.
Barnes, Geoffrey D.
Streiff, Michael B.
Responsibility
Joe F. Lau, Geoffrey D. Barnes, Michael B. Streiff, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2018
Physical Description
1 online resource (xxix, 452 p.) : 42 illus., 30 illus. in color
ISBN
9783319737096
9783319737089 (print ed.)
9783319737102 (print ed.)
Subjects (MeSH)
Anticoagulants - therapeutic use
Specialty
Hematology
Abstract
This book presents the latest evidence and guidelines supporting the use of anticoagulant therapy for various clinical scenarios. The field of anticoagulation therapy is evolving rapidly, particularly since the arrival and widespread adoption of direct oral anticoagulants. Organized in two parts, this book reviews the pharmacologic properties of various anticoagulants and details the clinical applications of anticoagulant therapy. Drugs such as warfarin and unfractionated heparin, as well as parenteral and direct oral anticoagulants are discussed in terms of their pharmacokinetics, drug-disease interactions, dosing strategies, and risk considerations. Clinical applications of anticoagulant therapy in disorders such as acute coronary syndromes, atrial fibrillation, and thrombophilia and in special populations such as pregnant women, the elderly, and in the patient with cancer are highlighted. Clinical vignettes, algorithms, clinical pearls, and self-assessment questions are integrated throughout the book. Featuring contributions from authorities in the field, Anticoagulation Therapy is an essential resource for cardiologists, vascular medicine specialists, hematologists, internists, and all other healthcare professionals who prescribe anticoagulants.
Contents
1. Introduction -- Part I. Anticoagulants -- 2. Warfarin -- 3. Unfractionated Heparin and Low-Molecular-Weight Heparin -- 4. Parenteral Anticoagulants: Direct Thrombin Inhibitors and Pentasaccharides -- 5. Direct Oral Anticoagulants -- 6. Anticoagulation Reversal -- 7. Transitioning Between Anticoagulants -- Part II. Clinical Applications of Anticoagulant Therapy -- 8. The Anticoagulation Clinic -- 9. Peri-Operative Management of Anticoagulants -- 10. Acute Coronary Syndromes -- 11. Antithrombotic Therapy for Patients with Atrial Fibrillation -- 12. Anticoagulant Strategies for Electrophysiology Procedures -- 13. Anticoagulation for Cardiac Prosthetic Devices: Prosthetic Heart Valves, Left Ventricular Assist Devices, and Septal Closure Devices -- 14. Anticoagulation in Venous Thromboembolism -- 15. Thrombophilic States -- 16. Thrombophilia Testing -- 17. Heparin-Induced Thrombocytopenia -- 18. Anticoagulation Therapy in Pregnant Patients -- 19. Anticoagulation in the Elderly -- 20. Anticoagulation in the Patient with Cancer.
Format
e-Book
Location
Online
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Atrial Fibrillation and Percutaneous Coronary Intervention : A Case-based Guide to Oral Anticoagulation, Antiplatelet Therapy and Stenting

https://libcat.nshealth.ca/en/permalink/provcat41420
Andrea Rubboli, Gregory Y. H. Lip, editors. --Cham: Springer , 2017.
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This book considers paradigmatic clinical cases in order to cast light on key issues relating to elective or emergency stent implantation and the use of oral anticoagulation (OAC) in patients with atrial fibrillation. The topics addressed include the optimal periprocedural antithrombotic treatment (uninterrupted vs interrupted OAC, intraprocedural use of heparin and glycoprotein IIb/IIIa inhibitors, etc.), the most appropriate type of stent (bare metal vs drug eluting vs "bioactive"), the optim…
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Other Authors
Rubboli, Andrea
Lip, Gregory Y. H.
Responsibility
Andrea Rubboli, Gregory Y. H. Lip, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
2017
Physical Description
1 online resource (viii, 212 pages) : 52 illus., 30 illus. in color
ISBN
9783319424002
9783319423982 (print ed.)
Subjects (MeSH)
Anticoagulants - therapeutic use
Atrial Fibrillation - drug therapy
Atrial Fibrillation - surgery
Percutaneous Coronary Intervention - methods
Vitamin K - therapeutic use
Abstract
This book considers paradigmatic clinical cases in order to cast light on key issues relating to elective or emergency stent implantation and the use of oral anticoagulation (OAC) in patients with atrial fibrillation. The topics addressed include the optimal periprocedural antithrombotic treatment (uninterrupted vs interrupted OAC, intraprocedural use of heparin and glycoprotein IIb/IIIa inhibitors, etc.), the most appropriate type of stent (bare metal vs drug eluting vs "bioactive"), the optimal regimen (e.g., triple therapy of OAC, aspirin, and clopidogrel vs the combination of OAC and a single antiplatelet agent), and the most suitable duration of the antithrombotic treatment prescribed at discharge (1 vs 6-12 months). The case-based management recommendations will be of wide practical value in the current health care context, where percutaneous coronary intervention is available even to patients with relevant co-morbidities, such as those warranting long-term OAC, and the indications for OAC are much broader than in the past. The book will appeal especially to clinical and interventional cardiologists, internal medicine specialists, hematologists, and family physicians and will also be of interest to cardiology and internal medicine residents and fellows.
Contents
Atrial fibrillation on vitamin K-antagonists undergoing elective coronary artery stenting for stable effort angina -- Atrial fibrillation on NOAC (dabigatran) undergoing elective coronary artery stenting for stable effort angina -- Atrial fibrillation on vitamin K-antagonist undergoing urgent coronary stenting for non ST-elevation acute coronary syndrome -- Atrial fibrillation on NOAC (rivaroxaban) undergoing urgent coronary stenting for non ST-elevation acute coronary syndrome -- Atrial fibrillation on vitamin K-antagonist undergoing emergency primary coronary stenting for ST-elevation acute myocardial infarction -- Atrial fibrillation on NOAC (apixaban) undergoing emergency primary coronary stenting for ST-elevation acute myocardial infarction -- Atrial fibrillation early complicating acute coronary syndrome treated with coronary artery stenting -- New-onset atrial fibrillation in a stable patient with remote coronary artery stenting -- Urgent surgery early after coronary stenting in a patient with atrial fibrillation on triple therapy of warfarin, aspirin and clopidogrel -- Urgent surgery early after coronary stenting in a patjent with atrial fibrillation on triple therapy of NOAC (a factor Xa-inhibitor), aspirin and clopidogrel -- Major bleeding early after coronary stenting in a patient with atrial fibrillation on triple therapy of warfarin, aspirin and clopidogrel -- Major bleeding early after coronary stenting in a patient with atrial fibrillation on triple therapy of NOAC (dabigatran), aspirin and clopidogrel.
Format
e-Book
Location
Online
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Consultative hemostasis and thrombosis

https://libcat.nshealth.ca/en/permalink/provcat32242
[edited by] Craig S. Kitchens, Craig M. Kessler, Barbara A. Konkle. (4th ed.) --Philadelphia, PA: Elsevier , c2019.
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With authoritative coverage of rare and common hemostatic disorders, Consultative Hemostasis and Thrombosis, 4th Edition, keeps you both up to date with all that’s new in this fast-moving field as well as reviewing background and development and citing pertinent classical literature. Broad differential diagnoses are provided, underscoring the editors’ position that correct treatment begins with correct diagnosis.
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Other Authors
Kitchens, Craig S
Kessler, Craig M
Konkle, Barbara A
Responsibility
[edited by] Craig S. Kitchens, Craig M. Kessler, Barbara A. Konkle
Edition
4th ed.
Alternate Title
Consultative hemostasis & thrombosis
Place of Publication
Philadelphia, PA
Publisher
Elsevier
Date of Publication
c2019
Physical Description
1 online resource, 872 p.
ISBN
9780323462020
Subjects (MeSH)
Blood Coagulation Disorders
Anticoagulants - therapeutic use
Blood Platelet Disorders
Fibrinolytic Agents - therapeutic use
Hemostasis - physiology
Thrombosis - pathology
Subjects (LCSH)
Blood coagulation disorders
Hemostasis
Blood Coagulation Disorders
Anticoagulants - therapeutic use
Blood Platelet Disorders
Fibrinolytic Agents - therapeutic use
Hemostasis - physiology
Thrombosis - pathology
Specialty
Hematology
Abstract
With authoritative coverage of rare and common hemostatic disorders, Consultative Hemostasis and Thrombosis, 4th Edition, keeps you both up to date with all that’s new in this fast-moving field as well as reviewing background and development and citing pertinent classical literature. Broad differential diagnoses are provided, underscoring the editors’ position that correct treatment begins with correct diagnosis.
Access
Registration required for PDF access.
Format
e-Book
Location
Online
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Consultative hemostasis and thrombosis

https://libcat.nshealth.ca/en/permalink/provcat50553
Kitchens, Craig. (4th ed.) --Philadelphia, PA: Elsevier , 2019.
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Location
Online
Available Online
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Author
Kitchens, Craig
Edition
4th ed.
Place of Publication
Philadelphia, PA
Publisher
Elsevier
Date of Publication
2019
ISBN
9780323462020
Subjects (MeSH)
Blood Coagulation Disorders
Anticoagulants - therapeutic use
Blood Platelet Disorders
Fibrinolytic Agents - therapeutic use
Hemostasis - physiology
Thrombosis - pathology
Notes
Access to this online resource is restricted to IWK Health Centre employees working from inside the hospital network.
Format
e-Book
Location
Online
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Handbook of oral anticoagulation

https://libcat.nshealth.ca/en/permalink/provcat33540
editors, Gregory YH Lip, Eduard Shantsila ; contributors, Deirdre A. Lane, Chee W. Khoo, Kok Hoon Tay, Suresh Krishnamoorthy, Stavros Apostolakis. (Second edition) --London: Springer Healthcare , c2013.
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This book covers a wide range of disorders such as atrial fibrillation, artificial heart valves, deep vein thrombosis, pulmonary embolism and stroke. Handbook of Oral Anticoagulation aims to provide an accessible overview of the exciting new developments in this field. Incorporating numerous quick-reference tables and figures and fully referenced throughout to key papers and the latest reviews, it will be a useful resource for all healthcare professionals involved in thromboprophylaxis.
Available Online
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Other Authors
Lip, Gregory Y. H
Shantsila, Eduard
Responsibility
editors, Gregory YH Lip, Eduard Shantsila ; contributors, Deirdre A. Lane, Chee W. Khoo, Kok Hoon Tay, Suresh Krishnamoorthy, Stavros Apostolakis
Edition
Second edition
Place of Publication
London
Publisher
Springer Healthcare
Date of Publication
c2013
Physical Description
1 online resource (ix, 88 pages)
ISBN
9781908517968 (electronic bk.)
9781908517586
Subjects (MeSH)
Anticoagulants - administration & dosage
Anticoagulants - adverse effects
Anticoagulants - therapeutic use
Subjects (LCSH)
Anticoagulants - Handbooks
Anticoagulants (Medicine)
Cardiology
Hematology
General Practice / Family Medicine
Primary Care Medicine
Pharmacotherapy
Abstract
This book covers a wide range of disorders such as atrial fibrillation, artificial heart valves, deep vein thrombosis, pulmonary embolism and stroke. Handbook of Oral Anticoagulation aims to provide an accessible overview of the exciting new developments in this field. Incorporating numerous quick-reference tables and figures and fully referenced throughout to key papers and the latest reviews, it will be a useful resource for all healthcare professionals involved in thromboprophylaxis.
Contents
The Coagulation Pathway and Approaches to Anticoagulation -- Common Clinical Indications for Anticoagulation -- Vitamin K Antagonists and Their Limitations -- Hemorrhage Risks, Patient Perspectives, and Quality-of-Life Issues -- New Oral Anticoagulants -- Future Directions.
Format
e-Book
Location
Online
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Handbook of Thromboprophylaxis

https://libcat.nshealth.ca/en/permalink/provcat39838
David Perry, David Warwick, editors. (Third edition) --Cham: Springer International Publishing : Imprint: Adis , c2016.
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Online
This third edition expands upon the role of anticoagulants in clinical practice. In addition, it summarizes new developments in the field and provides evidence-based guidelines for the use of anticoagulants in routine day-to-day practice. The Handbook of Thromboprophylaxis Third Edition is a key resource for all physicians with an interest in thromboprophylaxis.
Available Online
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Other Authors
Perry, David
Warwick, David
Responsibility
David Perry, David Warwick, editors
Edition
Third edition
Place of Publication
Cham
Publisher
Springer International Publishing : Imprint: Adis
Date of Publication
c2016
Physical Description
1 online resource (xiii, 118 p. : 12 illus., 2 illus. in color)
ISBN
9783319211480
9783319211473 (print ed.)
Subjects (MeSH)
Anticoagulants - therapeutic use
Embolism - drug therapy
Thrombosis - drug therapy
Abstract
This third edition expands upon the role of anticoagulants in clinical practice. In addition, it summarizes new developments in the field and provides evidence-based guidelines for the use of anticoagulants in routine day-to-day practice. The Handbook of Thromboprophylaxis Third Edition is a key resource for all physicians with an interest in thromboprophylaxis.
Contents
Introduction -- Overview of anticoagulants -- Thromboprophylaxis in medical patients -- Introduction to thromboprophylaxis in surgical patients -- Thromboprophylaxis in orthopedic surgery -- Thromboprophylaxis in cancer surgery -- Thromboprophylaxis in other types of surgery -- Thromboprophylaxis in pregnancy -- Venous thromboprophylaxis in children -- Thromboprophylaxis in cancer patients -- Travel-related thrombosis.
Format
e-Book
Publication Type
Handbook
Location
Online
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Hemostasis and Thrombosis

https://libcat.nshealth.ca/en/permalink/provcat44402
Thomas G. DeLoughery, editor. (Fourth edition) --Cham: Springer , c2019.
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Online
The latest edition of this practical handbook provides a concise yet comprehensive overview of common and rare problems with hemostasis and thrombosis. Through thoroughly updated and revised chapters, the text features practical information on diagnosing and managing troublesome hematologic conditions often found in clinical practice. The handbook also spotlights advances in the field since the publication of the last edition, including multiple novel coagulation factors for hemophilia, the inc…
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Other Authors
DeLoughery, Thomas G.
Responsibility
Thomas G. DeLoughery, editor
Edition
Fourth edition
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2019
Physical Description
1 online resource (vii, 236 p.) : 12 illus., 7 illus. in color
ISBN
9783030193300
9783030193294 (Print ed.)
9783030193317 (Print ed.)
Subjects (MeSH)
Anticoagulants - therapeutic use
Blood Coagulation Disorders
Hemostasis
Hemostatic Disorders
Thrombosis
Specialty
Hematology
Abstract
The latest edition of this practical handbook provides a concise yet comprehensive overview of common and rare problems with hemostasis and thrombosis. Through thoroughly updated and revised chapters, the text features practical information on diagnosing and managing troublesome hematologic conditions often found in clinical practice. The handbook also spotlights advances in the field since the publication of the last edition, including multiple novel coagulation factors for hemophilia, the increasing use of novel anticoagulants and their reversal agents, and the increasing use of genetics for diagnosis. Written by experts in the field, Hemostasis and Thrombosis, Fourth Edition is an invaluable resource for healthcare professionals who treat patients afflicted with these conditions.
Contents
Basics of Coagulation -- Tests of Hemostasis and Thrombosis -- Bleeding Disorders: A General Approach -- Hemophilia -- von Willebrand Disease -- Other Inherited Bleeding Disorders -- Acquired Bleeding Disorders -- Disseminated Intravascular Coagulation -- Liver and Renal Disease -- Cardiac Bypass and Ventricular Assist Devices/ECMO -- Immune Thrombocytopenia -- Thrombotic Microangiopathy (TTP/HUS) -- Non-Blood Product Agents for Bleeding Disorders -- Transfusion Therapy and Massive Transfusions -- Deep Venous Thrombosis and Pulmonary Embolism -- Thrombosis in Unusual Sites -- Inherited Thrombophilias -- Aquired Thrombophilias -- Antiphospholipid Antibody Syndrome -- Antithrombotic Therapy for Cardiac Disease -- Stroke and Peripheral Vascular Disease -- Heparins and Heparin-Induced Thrombocytopenia -- Other Parenteral Anticoagulants -- Direct Oral Anticoagulants -- Warfarin -- Antiplatelet Agents -- Thrombolytic Therapy -- Clinical Dilemmas In Anticoagulation: Extremes Of Weight, Renal Disease, Recent Bleeding, And Surgery -- Bleeding and Thrombosis in Cancer Patients -- Hemostasis and Thrombosis in Pregnancy -- Hemorrhage and Thrombosis in Women -- Pediatric Thrombosis.
Format
e-Book
Location
Online
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Non-Vitamin K Antagonist Oral Anticoagulants : A Concise Guide

https://libcat.nshealth.ca/en/permalink/provcat39979
Eduard Shantsila, Gregory YH Lip. --Cham: SpringerOpen ; Adis , c2016.
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Access
Open access
Location
Online
This book is an essential guide to the medical treatment of thrombosis and presents core principles of anticoagulant therapeutics as well as drug recommendations. Written by recognized experts in the field, this concise, accessible handbook provides a unique and valuable resource in the cardiovascular field, both for those currently in training, and for those already in clinical or research practice.
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Author
Shantsila, Eduard
Other Authors
Lip, Gregory YH
Responsibility
Eduard Shantsila, Gregory YH Lip
Place of Publication
Cham
Publisher
SpringerOpen ; Adis
Date of Publication
c2016
Physical Description
1 online resource (x, 50 p.) : 13 illus., 7 illus. in color
ISBN
9783319254609
9783319254586 (print ed.)
Subjects (MeSH)
Anticoagulants - therapeutic use
Antithrombins - therapeutic use
Factor Xa Inhibitors - therapeutic use
Specialty
Hematology
Pharmacology
Abstract
This book is an essential guide to the medical treatment of thrombosis and presents core principles of anticoagulant therapeutics as well as drug recommendations. Written by recognized experts in the field, this concise, accessible handbook provides a unique and valuable resource in the cardiovascular field, both for those currently in training, and for those already in clinical or research practice.
Contents
1. Introduction -- 2. Direct thrombin inhibitors -- 3. Factor Xa inhibitors -- 4. Conclusions.
Access
Open access
Format
e-Book
Location
Online
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Oral Anticoagulation Therapy : Cases and Clinical Correlation

https://libcat.nshealth.ca/en/permalink/provcat41753
Kathryn Kiser, editor. --Cham: Springer , 2017.
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Location
Online
This case-based title reviews anticoagulation management strategies available for a wide variety of clinical scenarios. Designed to aid providers of direct patient care on complex clinical decisions regarding appropriate evidence-based therapy options, patient and agent related variables to consider, as well as expert opinion on the topic. Oral Anticoagulation Therapy: Cases and Clinical Correlation will provide clinicians and trainees with clear clinical cases, commentary, and resources to dev…
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Other Authors
Kiser, Kathryn
Responsibility
Kathryn Kiser, editor
Place of Publication
Cham
Publisher
Springer
Date of Publication
2017
Physical Description
1 online resource (x, 313 pages) : 6 illus., 2 illus. in color
ISBN
9783319546438
9783319546414 (print ed.)
Subjects (MeSH)
Administration, Oral
Anticoagulants - therapeutic use
Hemorrhage - drug therapy
Vascular Diseases - drug therapy
Warfarin - therapeutic use
Abstract
This case-based title reviews anticoagulation management strategies available for a wide variety of clinical scenarios. Designed to aid providers of direct patient care on complex clinical decisions regarding appropriate evidence-based therapy options, patient and agent related variables to consider, as well as expert opinion on the topic. Oral Anticoagulation Therapy: Cases and Clinical Correlation will provide clinicians and trainees with clear clinical cases, commentary, and resources to develop their knowledge base, problem-solving skills, and ability to practically apply new knowledge to a variety of clinical situations. Resources provided in cases include valuable figures, tables, and key points designed for the reader to be able to utilize at the point of care.
Contents
Part I: Introduction -- 1. Introduction -- Part II: Atrial Fibrillation -- 2. CHA2DS2-VASc and HAS-BLED Risk Stratification Tools -- 3. Male with Priority of Ischemic Stroke Reduction -- 4. Choosing an Anticoagulant in an Elderly Patient -- 5. Patient with Prior History of GI Hemorrhage -- 6. Patients with a History of Intracranial Hemorrhage -- 7. Concerns with Anticoagulant Adherence -- 8. Oral Anticoagulants in Stable Moderate Chronic Kidney Disease -- 9. Oral Anticoagulants in Severe Renal Dysfunction -- 10. Oral Anticoagulants in Patients with Variable Renal Function -- 11. Patient with Concomitant Stable Coronary Artery Disease -- 12. Patient with Concomitant Acute Venous Thromboembolism -- 13. Patient with Concomitant Mitral Valve Stenosis -- 14. Patient with Concomitant Aortic Valve Stenosis -- Part III: Warfarin Management -- 15. Best Practice for Switching Stable Warfarin Patients -- 16. Patient-Centered Strategies for Improving Warfarin Management -- Part IV: Venous Thromboembolism (VTE) -- 17. Provoked Versus Unprovoked Venous Thromboembolism -- 18. Venous Thromboembolism (VTE) Prophylaxis in Hip and Knee Replacement Surgery -- 19. Venous Thromboembolism (VTE) Prophylaxis in the Intensive Care Unit (ICU) -- 20. VTE and Recent Drug Eluting Stent (DES) Placement -- 21. Acute VTE in a Patient with Moderate Chronic Kidney Disease -- 22. Oral Anticoagulation and Duration in Recurrent Venous Thromboembolism (VTE) -- 23. Pulmonary Embolism (PE) with Thrombolytic Therapy -- Part V: Acute Coronary Syndrome (ACS) -- 24. Patient on Oral Anticoagulant Presenting with ACS -- 25. Oral Anticoagulant Therapy Post-Percutaneous Coronary Intervention -- 26. ST-Segment Elevation Myocardial Infarction (Lytic Candidate) on Oral Anticoagulant -- 27. ACS with Bypass Surgery -- Part VI: Drug Interactions -- 28. Anticoagulant Drug-Drug Interactions with CYP 3A4 Inhibitors -- 29. Significance of P-glycoprotein (P-gp) Drug-Drug Interactions -- 30. Considerations with Pharmacodynamic Drug-Drug Interactions -- 31. Management of Direct Oral Anticoagulants with Mixed P-gp/3A4 Drug-Drug Interactions -- 32. Pharmacokinetic Drug-Drug Interactions with Warfarin -- Part VII: Special Populations -- 33. Chronic Pain Management with Anticoagulation -- 34. Anticoagulation Management in Atrial Fibrillation Catheter Ablation -- 35. Anticoagulation Management Considerations for Mechanical Valves -- 36. Management of Antiphospholipid Antibody Syndrome -- 37. Venous Thromboembolism and Pregnancy -- 38. Venous Thromboembolism in Active Malignancy -- 39. Anticoagulation Management in Patients Undergoing Gastric Bypass Procedures -- 40. Patient Presenting with Minor Bleeding -- 41. Patient Presenting with Major, Life-Threatening Bleeding -- 42. Overdose of Dabigatran.
Format
e-Book
Location
Online
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Pharmacological treatment of acute coronary syndromes

https://libcat.nshealth.ca/en/permalink/provcat33393
Pablo Avanzas, Peter Clemmensen, editors. --London: Springer ; ISCP , c2014.
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Location
Online
Cardiovascular pharmacotherapy is a fast-moving and complex discipline within cardiology in general. New studies, trials and indications are appearing on a regular basis. This series, and this particular title within the series, is designed to establish the baseline level of knowledge that a cardiovascular professional needs to know on a day-to-day basis. The information within is designed to allow readers to learn quickly and with certainty the mode of action, the possible adverse effects, and…
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Corporate Author
International Society of Cardiovascular Pharmacotherapy
Other Authors
Avanzas, Pablo
Clemmensen, Peter
Responsibility
Pablo Avanzas, Peter Clemmensen, editors
Place of Publication
London
Publisher
Springer ; ISCP
Date of Publication
c2014
Physical Description
1 online resource (xvi, 245 pages)
Series Title
Current cardiovascular therapy
ISBN
9781447154242 (electronic bk.)
9781447154235
Subjects (MeSH)
Acute Coronary Syndrome - drug therapy
Anticoagulants - therapeutic use
Platelet Aggregation Inhibitors - therapeutic use
Subjects (LCSH)
Cardiovascular pharmacology
Heart - Diseases - Chemotherapy
Coronary heart disease
Electrocardiography
Pharmacology
Acute coronary syndrome - Diagnosis
Abstract
Cardiovascular pharmacotherapy is a fast-moving and complex discipline within cardiology in general. New studies, trials and indications are appearing on a regular basis. This series, and this particular title within the series, is designed to establish the baseline level of knowledge that a cardiovascular professional needs to know on a day-to-day basis. The information within is designed to allow readers to learn quickly and with certainty the mode of action, the possible adverse effects, and the management of patients prescribed these drugs.
Contents
1. Anti-ischemic Therapy -- 2. Antiaggregant Therapy: New potent P2Y12 inhibitors -- 3. Anticoagulation Therapy: Heparins and Factor Xa inhibitors -- 4. Secondary prevention in ACS: The role of novel oral anticoagulants -- 5. American versus European guidelines: Critical appraisal -- 6. Triple therapy: Risky but sometimes necessary -- 7. Management of bleeding complications.
Format
e-Book
Location
Online
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Precision Anticoagulation Medicine : A Practical Guide

https://libcat.nshealth.ca/en/permalink/provcat44865
Hadi Goubran, Gaafar Ragab, Suzy Hassouna, editors. --Cham: Springer , c2020.
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Online
This book provides a practical guide to the use of novel and conventional anticoagulants for a variety of medical conditions and patients profiled. It reviews data for selecting the most appropriate medication for a given presentation based on a patient’s background while highlighting current best practices. Chapters discuss the choice of agents and optimum duration of therapy while including the relevant literature review and evidence. Specific sections focus on the use of anticoagulants in pa…
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Other Authors
Goubran, Hadi
Ragab, Gaafar
Hassouna, Suzy
Responsibility
Hadi Goubran, Gaafar Ragab, Suzy Hassouna, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2020
Physical Description
1 online resource (xv, 308 p.) ; 28 illus., 20 illus. in color
ISBN
9783030257828
9783030257811 (Print ed.)
9783030257835 (Print ed.)
Subjects (MeSH)
Anticoagulants - therapeutic use
Precision Medicine
Specialty
Hematology
Pharmacology
Abstract
This book provides a practical guide to the use of novel and conventional anticoagulants for a variety of medical conditions and patients profiled. It reviews data for selecting the most appropriate medication for a given presentation based on a patient’s background while highlighting current best practices. Chapters discuss the choice of agents and optimum duration of therapy while including the relevant literature review and evidence. Specific sections focus on the use of anticoagulants in patients with cardiovascular disease, autoimmune and rheumatologic disorders, antiphospholipid syndrome, cancer, and in the surgical contexts. The book also examines anticoagulation in pregnant and lactating women, pediatric and elderly populations, and patients with extreme weights. Intended for use in daily practice, Precision Anticoagulation Medicine - A Practical Guide is an essential resource for physicians and related professionals, residents, fellows, and graduate students in hematology, cardiology, rheumatology, oncology, surgery, anesthesiology, and intensive care.
Contents
1. Coagulation and Anticoagulants -- 2. Routine Anticoagulation for the Provoked and Unprovoked VTE -- 3. Anticoagulation in Cardiac Patients -- 4. Thrombosis and Anticoagulation in Children -- 5. Cancer Associated Thrombosis (CAT) -- 6. Anticoagulation in Pregnancy and Lactation -- 7. Anticoagulation in Autoimmune Rheumatic Diseases -- 8. Antiphospholipid Syndrome -- 9. Anticoagulation in patients with renal insufficiency -- 10. VTE prophylaxis in General and Orthopedic Surgery -- 11. Thromboprophylaxis for Hospitalized Medical Patients -- 12. Perioperative management of anticoagulation and antiplatelet therapy -- 13. Anticoagulation Reversal Guide and Reversal Agents.
Format
e-Book
Location
Online
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Thrombosis and embolism : from research to clinical practice, volume 1

https://libcat.nshealth.ca/en/permalink/provcat41268
Md. Shahidul Islam, editor. --Cham: Springer , 2017.
Available Online
View e-Book
Location
Online
This unique publication explores diverse themes relating to thrombosis and embolism, from basic research at cell and molecular level to the actual care, prevention, and treatment of diverse categories of patients suffering from such diseases. Chapters cover a variety of topics including thrombosis and embolism in surgical patients, cancer patients, pregnant women and children and adolescents, as well as treatment of the conditions by traditional anticoagulants, novel oral anticoagulants, thromb…
Available Online
View e-Book
Other Authors
Islam, Md. Shahidul
Responsibility
Md. Shahidul Islam, editor
Place of Publication
Cham
Publisher
Springer
Date of Publication
2017
Physical Description
1 online resource (ix, 429 pages) : 30 illus., 15 illus. in color
Series Vol.
906
Series Title
Advances in experimental medicine and biology
Advances in internal medicine
ISBN
9783319221083
9783319221076 (print ed.)
ISSN
0065-2598
Subjects (MeSH)
Anticoagulants - therapeutic use
Pulmonary Embolism
Venous Thromboembolism
Abstract
This unique publication explores diverse themes relating to thrombosis and embolism, from basic research at cell and molecular level to the actual care, prevention, and treatment of diverse categories of patients suffering from such diseases. Chapters cover a variety of topics including thrombosis and embolism in surgical patients, cancer patients, pregnant women and children and adolescents, as well as treatment of the conditions by traditional anticoagulants, novel oral anticoagulants, thrombolytic therapy, endovascular treatment and embolectomy. Readers may explore cutting edge research, recommendations from major societies, contemporary guidelines, areas of controversy and directions for ongoing and future research. The book features comprehensive information ranging from molecular mechanisms of diseases to the clinical features, diagnosis, and therapeutic regimens for treating a variety of clinical conditions. It has a broad appeal to scientists and research students as well as busy clinicians engaged in patient care, who will all find something important and useful amongst these carefully selected chapters.
Format
e-Book
Location
Online
Less detail

Topics in palliative care. Vol. 4

https://libcat.nshealth.ca/en/permalink/provcat22629
Portenoy, Russell K. --New York, NY: Oxford University Press , 2000.
Call Number
WB 310 T674 2000 v.4
Location
Dickson Building
Call Number
WB 310 T674 2000 v.4
Author
Portenoy, Russell K
Other Authors
Bruera, Eduardo
Place of Publication
New York, NY
Publisher
Oxford University Press
Date of Publication
2000
Physical Description
288 p.
Series Vol.
v. 4
Series Title
Topics in palliative care
ISBN
019513219X
Subjects (MeSH)
Palliative Care
Survival Analysis
Coagulants - therapeutic use
Anticoagulants - therapeutic use
Contents
I. Survival estimation in palliative care -- II. Education and training in palliative care -- III. Procoagulant and anticoagulant therapy in palliative care -- IV. Issues in the assessment and management of common symptoms.
Format
Book
Location
Dickson Building
Loan Period
3 weeks
Less detail

Treatment of Non-vitamin K Antagonist Oral Anticoagulants : For Prevention of Stroke

https://libcat.nshealth.ca/en/permalink/provcat41950
Masaaki Uno, Kuniaki Ogasawara, editors. --Singapore: Springer , 2017.
Available Online
View e-Book
Location
Online
This book describes new concepts and strategies for the clinical application of non-vitamin K antagonist oral anticoagulants (NOACs) for stroke. Although vitamin K antagonists have traditionally been used for the prevention of stroke, there are some problems associated with their use, such as the risk of intracranial hemorrhage, the need for dietary restrictions, and individual variability. Recently, NOACs have been introduced as alternatives to traditional anticoagulants and are becoming an op…
Available Online
View e-Book
Other Authors
Uno, Masaaki
Ogasawara, Kuniaki
Responsibility
Masaaki Uno, Kuniaki Ogasawara, editors
Place of Publication
Singapore
Publisher
Springer
Date of Publication
2017
Physical Description
1 online resource (ix, 99 pages) : 31 illus., 13 illus. in color
ISBN
9789811018787
9789811018770 (print ed.)
Subjects (MeSH)
Anticoagulants - therapeutic use
Stroke - prevention & control
Vitamin K - antagonists & inhibitors
Abstract
This book describes new concepts and strategies for the clinical application of non-vitamin K antagonist oral anticoagulants (NOACs) for stroke. Although vitamin K antagonists have traditionally been used for the prevention of stroke, there are some problems associated with their use, such as the risk of intracranial hemorrhage, the need for dietary restrictions, and individual variability. Recently, NOACs have been introduced as alternatives to traditional anticoagulants and are becoming an option for treating stroke patients around the globe. However, their use is not without risk. Each chapter describes the successful use of NOACs for stroke patients and discusses their future impact from various points of view. The book is primarily written for neurosurgeons and neurologists but is also of interest to cardiologists involved in stroke treatment.
Contents
1 .Intracranial Bleeding -- 2. Severity and Outcomes of Intracerebral Bleeding and Cardiac Cerebral Embolism -- 3. Influence for Intracranial Bleeding Surgery -- 4. New Approaches for the Secondary Prevention of Cryptogenic Stroke Using Non-Vitamin K Antagonist Oral Anticoagulants -- 5. Secondary Prevention of Cerebral Infarct: Verification of Appropriateness in Choices of Anticoagulant by Comparison of Current and previous Treatment Results -- 6. Putaminal Hemorrhage in Patients with Oral Anticoagulants -Course of Treatment and Results of Endoscopic Evacuation -- 7. Secondary Prevention of Stroke with Atrial Fibrillation by New Oral Anticoagulants -- 8. Causes and Outcome in Patients with Cerebral Hemorrhage Using Anticoagulated Drugs.
Format
e-Book
Location
Online
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