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Combination therapy in hypertension

https://libcat.nshealth.ca/en/permalink/provcat33281
Joel M. Neutel. --London: Springer Healthcare , c2011.
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Location
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For over 30 years, the stepped care approach has been used in the management and treatment of hypertension. This approach advocates the use of initial monotherapy to reach the desired blood pressure, and the subsequent use of additional drugs with complementary modes of action, until the target BP is achieved. However, current control rates for hypertension suggest that such an approach may be outdated and no longer effective in the management of hypertension. Clinical trials have shown that mo…
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Author
Neutel, Joel M
Responsibility
Joel M. Neutel
Place of Publication
London
Publisher
Springer Healthcare
Date of Publication
c2011
Physical Description
1 online resource (vii, 84 pages)
ISBN
9781908517289 (electronic bk.)
9781908517258
Subjects (MeSH)
Hypertension - therapy
Antihypertensive Agents - therapeutic use
Subjects (LCSH)
Cardiology
Pharmacotherapy
Primary Care Medicine
Angiology
General Practice / Family Medicine
Hypertension - Treatment
M├ędecine
Abstract
For over 30 years, the stepped care approach has been used in the management and treatment of hypertension. This approach advocates the use of initial monotherapy to reach the desired blood pressure, and the subsequent use of additional drugs with complementary modes of action, until the target BP is achieved. However, current control rates for hypertension suggest that such an approach may be outdated and no longer effective in the management of hypertension. Clinical trials have shown that more than 50% of patients require a combination of drug therapies to achieve their target BP. Some proponents of combination therapy have argued that the risk of adverse side effects and non-compliance will be lower than that compared to monotherapy, which initially requires higher doses to be administered to be effective. Consequently, there have been increasing calls of the necessity for a much more combined approach in the treatment of hypertension. Adding to this, Combination Therapy in Hypertension will cover current control rates of blood pressure worldwide, the benefits of monotherapy and combination therapy, examine the effectiveness, risk of adverse effects, compliance, and cost of the available therapies and will also include information on relevant outcome studies.
Contents
State of Hypertension Control -- Historical Review of Combination Therapy -- Advantages of Combination Therapy Compared with Monotherapy -- Use of Combination Therapy in Special Populations -- The Evidence Base for Combination Therapy -- Combination Therapy as First-Line Treatment -- Future Combination Agents -- Clinical Inertia in the Management of Hypertension.
Format
e-Book
Location
Online
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Hypertension : a companion to Brenner and Rector's the kidney

https://libcat.nshealth.ca/en/permalink/provcat22072
Oparil, Suzanne. (2nd ed.) --Philadelphia, PA: Elsevier Saunders , 2005.
Call Number
WG 340 H998 2005
Holdings
Halifax Infirmary: v. 15, 1990 - v. 24, 1994.
Location
Halifax Infirmary
Call Number
WG 340 H998 2005
Author
Oparil, Suzanne
Other Authors
Weber, Michael A
Edition
2nd ed.
Place of Publication
Philadelphia, PA
Publisher
Elsevier Saunders
Date of Publication
2005
Holdings
Halifax Infirmary: v. 15, 1990 - v. 24, 1994.
Physical Description
872 p.
ISBN
0721602584
ISSN
0194-911X
Subjects (MeSH)
Hypertension - physiopathology
Hypertension - complications
Hypertension - therapy
Antihypertensive Agents - therapeutic use
Format
Book
Location
Halifax Infirmary
Loan Period
3 weeks
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Hypertension and Organ Damage : A Case-Based Guide to Management

https://libcat.nshealth.ca/en/permalink/provcat39972
Giuliano Tocci. (1st ed.) --Cham: Springer , c2016.
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Location
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This book is designed to assist physicians in choosing among diagnostic procedures and therapeutic options when caring for patients with hypertension and markers of organ damage. The comprehensive description of practical clinical cases sets this book apart from other publications and will help the reader to transfer general guideline recommendations to the clinical setting. With this purpose, the cases have been selected to reflect situations frequently encountered during clinical routine, rat…
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Author
Tocci, Giuliano
Responsibility
Giuliano Tocci
Edition
1st ed.
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2016
Physical Description
1 online resource (xiii, 119 p. : 60 illus., 30 illus. in color)
Series Title
Practical case studies in hypertension management
ISBN
9783319250977
9783319250953 (print ed.)
ISSN
2364-6632
Subjects (MeSH)
Antihypertensive Agents - therapeutic use
Biomarkers - metabolism
Comorbidity
Hypertension - complications
Hypertension - drug therapy
Abstract
This book is designed to assist physicians in choosing among diagnostic procedures and therapeutic options when caring for patients with hypertension and markers of organ damage. The comprehensive description of practical clinical cases sets this book apart from other publications and will help the reader to transfer general guideline recommendations to the clinical setting. With this purpose, the cases have been selected to reflect situations frequently encountered during clinical routine, rather than hypertensive crises or emergencies or the rare presentations that tend to be addressed in case reports in scientific journals. The scenarios considered include treated hypertension with uncontrolled blood pressure levels in patients with left ventricular hypertrophy, diastolic dysfunction, carotid atherosclerosis, microalbuminuria and renal impairment, proteinuria and renal disease, and abnormal pulse pressure. By representing clinical practice in a "real world" setting, these paradigmatic cases will enable the practitioner to select the diagnostic tools and form of treatment best suited to the individual patient and the particular cardiovascular risk profile, thereby optimizing outcomes.
Contents
Case 1. Patient with essential hypertension and left ventricular hypertrophy -- Case 2. Patient with essential hypertension and diastolic dysfunction -- Case 3. Patient with essential hypertension and microalbuminuria -- Case 4. Patient with essential hypertension and proteinuria -- Case 5. Patient with essential hypertension and atherosclerosis -- Case 6. Patient with essential hypertension and high pulse pressure.
Format
e-Book
Publication Type
Case Reports
Location
Online
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Hypertension and Stroke : Pathophysiology and Management

https://libcat.nshealth.ca/en/permalink/provcat40114
Venkatesh Aiyagari, Philip B. Gorelick, editors. (Second edition) --Cham: Springer International Publishing : Imprint: Humana Press , c2016.
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Location
Online
The second edition of this work continues to address the intimate pathophysiologic relationship between hypertension and stroke. The editors and authors clearly and concisely synthesize our developing knowledge of this relationship and place epidemiologic and physiologic information into a practical clinical context. Comprehensive chapters present the evidence supporting strategies for stroke prevention and care, including blood pressure lowering therapies, anti-coagulation, and management of o…
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Other Authors
Aiyagari, Venkatesh
Gorelick, Philip B
Responsibility
Venkatesh Aiyagari, Philip B. Gorelick, editors
Edition
Second edition
Place of Publication
Cham
Publisher
Springer International Publishing : Imprint: Humana Press
Date of Publication
c2016
Physical Description
1 online resource (xix, 353 p. : 46 illus., 18 illus. in color)
Series Title
Clinical hypertension and vascular diseases
ISBN
9783319291529
9783319291505 (print ed.)
Subjects (MeSH)
Antihypertensive Agents - therapeutic use
Cerebrovascular Disorders - prevention & control
Hypertension - physiopathology
Hypertension - therapy
Stroke - prevention & control
Abstract
The second edition of this work continues to address the intimate pathophysiologic relationship between hypertension and stroke. The editors and authors clearly and concisely synthesize our developing knowledge of this relationship and place epidemiologic and physiologic information into a practical clinical context. Comprehensive chapters present the evidence supporting strategies for stroke prevention and care, including blood pressure lowering therapies, anti-coagulation, and management of other cerebrovascular risk factors. In addition to prescriptive measures for first stroke prevention, the book illuminates current regimens for care immediately after acute stroke and for the prevention of recurrent stroke. This latest edition also features extensively updated chapters from the previous edition, as well as new chapters on the effects of hypertension and stroke on the cerebral vasculature, blood pressure management in subarachnoid hemorrhage, and blood pressure variability, antihypertensive therapy, and stroke risk. Written by experts in the field, Hypertension and Stroke: Pathophysiology and Management, Second Edition is of great utility for specialists in neurology and cardiovascular medicine and a valuable practical resource for all physicians caring for older adults and hypertensive patients. .
Contents
Blood Pressure: Definition, Diagnosis, and Management -- The Link Between Hypertension and Stroke: Summary of Observational Epidemiological Studies -- Blood Pressure Control and Primary Prevention of Stroke: Summary of Clinical Trial Data -- Mechanisms Underlying Essential Hypertension: Neurogenic and Non-neurogenic -- The Effects of Hypertension and Stroke on the Cerebral Vasculature -- Pathophysiology and Mechanisms Whereby Hypertension May Cause Stroke -- Cardiovascular Risk Assessment, Summary of Guidelines for the Management of Hypertension and a Critical Appraisal of the 2014 Expert Panel of the National Institutes of Health Report -- Acute Blood Pressure Management After Ischemic Stroke -- Hypertensive Encephalopathy, Posterior Reversible Encephalopathy Syndrome, and Eclampsia -- Acute Blood Pressure Management After Intracerebral Hemorrhage -- Blood Pressure Management in Subarachnoid Hemorrhage: The Role of Blood Pressure Manipulation in Prevention of Rebleeding and the Management of Vasospasm -- Recurrent Stroke Prevention I: Diuretic and Angiotensin-Converting Enzyme Inhibitors (ACEIs): The PROGRESS Trial -- Blood Pressure Variability, Antihypertensive Therapy and Stroke Risk -- A Review of Antihypertensive Drugs and Choosing the Right Antihypertensive for Recurrent Stroke Prevention -- Vascular Cognitive Impairment and Alzheimer Disease: Are These Disorders Linked to Hypertension and Other Cardiovascular Risk Factors? -- Hypertension, Cerebral Small Vessel Disease, and Cognitive Function -- Cerebral Microbleeds, Small-Vessel Disease of the Brain, Hypertension and Cognition -- Neuroimaging of Hypertension and Related Cerebral Pathology.
Format
e-Book
Location
Online
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Hypertension guidelines for family medicine

https://libcat.nshealth.ca/en/permalink/provcat22991
Hypertension Review Panel. --Toronto, ON: MUMS Guideline Clearinghouse , 2008.
Call Number
WG 340 H998 2008 REF
Location
Dickson Building
Sub-Location
REFERENCE
Call Number
WG 340 H998 2008 REF
Corporate Author
Hypertension Review Panel
Place of Publication
Toronto, ON
Publisher
MUMS Guideline Clearinghouse
Date of Publication
2008
Physical Description
96 p.
ISBN
9781894332071
Subjects (MeSH)
Hypertension - therapy - practice guideline
Antihypertensive Agents - therapeutic use - Practice Guideline
Format
Book
Location
Dickson Building
Sub-Location
REFERENCE
Copies
2
Loan Period
In library use
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Hypertension in the Elderly

https://libcat.nshealth.ca/en/permalink/provcat28307
edited by L. Michael Prisant. --Totowa, NJ: Humana Press , c2005.
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Location
Online
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Author
Prisant, L. Michael
Responsibility
edited by L. Michael Prisant
Place of Publication
Totowa, NJ
Publisher
Humana Press
Date of Publication
c2005
Series Title
Clinical hypertension and vascular diseases
ISBN
9781592599110
Subjects (MeSH)
Hypertension - etiology
Hypertension - drug therapy
Antihypertensive Agents - therapeutic use
Subjects (LCSH)
Cardiology
Geriatrics
Format
e-Book
Location
Online
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6 records – page 1 of 1.