Autoantibodies
https://libcat.nshealth.ca/en/permalink/provcat27203
edited by Yehuda Shoenfeld, Pier Luigi Meroni, M. Eric Gershwin.
(3rd ed.)
--Oxford, UK:
Elsevier
, c2014.
- Available Online
- View e-Book
- Access
- Registration required for PDF access.
- Location
- Online
- Available Online
- View e-Book
- Author
- Shoenfeld, Yehuda
- Other Authors
- Meroni, Pier-Luigi
- Gershwin, M. Eric
- Responsibility
- edited by Yehuda Shoenfeld, Pier Luigi Meroni, M. Eric Gershwin
- Edition
- 3rd ed.
- Place of Publication
- Oxford, UK
- Publisher
- Elsevier
- Date of Publication
- c2014
- Physical Description
- 1 online resource
- ISBN
- 9780444563781
- Subjects (MeSH)
- Autoantibodies
- Autoimmune Diseases - etiology
- Access
- Registration required for PDF access.
- Format
- e-Book
- Location
- Online
Autoantibodies
https://libcat.nshealth.ca/en/permalink/provcat50403
Shoenfeld, Yehuda.
(3rd ed.)
--Amsterdam, Netherlands:
Elsevier
, 2014.
- Available Online
- View e-Book
- Location
- Online
- Available Online
- View e-Book
- Author
- Shoenfeld, Yehuda
- Other Authors
- Meroni, Pier Luigi
- Gershwin, M. Eric
- Edition
- 3rd ed.
- Place of Publication
- Amsterdam, Netherlands
- Publisher
- Elsevier
- Date of Publication
- 2014
- ISBN
- 9780444563781
- Subjects (MeSH)
- Autoantibodies
- Autoimmune Diseases - etiology
- Notes
- Access to this online resource is restricted to IWK Health Centre employees working from inside the hospital network.
- Format
- e-Book
- Location
- Online
Autoimmune Bullous Diseases : Approach and Management
https://libcat.nshealth.ca/en/permalink/provcat40013
Naveed Sami, editor.
(1st ed.)
--Cham:
Springer
, c2016.
- Available Online
- View e-Book
- Location
- Online
This book provides a coherent synopsis on the treatment and management of autoimmune blistering diseases. Each chapter focuses on one condition, and summarizes the present-day literature on currently available therapies, and how they may fit into various feasible treatment algorithms. Many of these disorders can have irreversible consequences, and in some cases the potential to be fatal. The contributing authors are individuals who have devoted their careers to understanding these diseases, and…
- Available Online
- View e-Book
- Other Authors
- Sami, Naveed
- Responsibility
- Naveed Sami, editor
- Edition
- 1st ed.
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2016
- Physical Description
- 1 online resource (xv, 265 p. : 54 illus., 4 illus. in color)
- ISBN
- 9783319267289
- 9783319267265 (print ed.)
- Subjects (MeSH)
- Autoimmune Diseases
- Pemphigoid, Bullous
- Pemphigus
- Skin Diseases, Vesiculobullous - therapy
- Abstract
- This book provides a coherent synopsis on the treatment and management of autoimmune blistering diseases. Each chapter focuses on one condition, and summarizes the present-day literature on currently available therapies, and how they may fit into various feasible treatment algorithms. Many of these disorders can have irreversible consequences, and in some cases the potential to be fatal. The contributing authors are individuals who have devoted their careers to understanding these diseases, and have invested countless hours in their research laboratories and clinical settings. Autoimmune Bullous Diseases: Approach and Management serves as a guide in assisting clinicians to develop their approach to treatment based on the specific disease and its severity. The information and algorithms presented provide pragmatic direction and assistance in the management of patients with these diseases.
- Contents
- 1 Pemphigus Vulgaris -- 2 Pemphigus Foliaceus -- 3 Pemphigus Herpetiformis -- 4 Bullous Pemphigoid -- 5 Ocular Cicatricial Pemphigoid -- 6 Mucous Membrane Pemphigoid -- 7 Linear IgA Bullous Dermatosis -- 8 Epidermolysis Bullosa Acquisita -- 9 Pemphigoid Gestationis -- 10 Dermatitis Herpetiformis -- 11 Rare Autoimmune Blistering Disorders -- 12 Autoimmune Blistering Diseases in Children -- 13 Systemic Corticosteroids -- 14 Local Treatments and Supportive Care.
- Format
- e-Book
- Location
- Online
Autoimmune Bullous Diseases : Text and Review
https://libcat.nshealth.ca/en/permalink/provcat39936
Marcel F. Jonkman, editor.
(1st ed.)
--Cham:
Springer
, c2016.
- Available Online
- View e-Book
- Location
- Online
This book provides a quick study and reference guide for physicians who treat patients with autoimmune bullous diseases (AIBDs), the most life-threatening inflammatory diseases of the skin. AIBDs are rare, and comprise less than 1% of the dermatological patients. As such, they are often given little focus in general dermatology literature, despite being complicated and demanding diseases . Autoimmune Bullous Diseases Study Guide: Text and Review is written in direct and simple diction with tabl…
- Available Online
- View e-Book
- Other Authors
- Jonkman, Marcel F
- Responsibility
- Marcel F. Jonkman, editor
- Edition
- 1st ed.
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2016
- Physical Description
- 1 online resource (xii, 221 p. : 111 illus., 1 illus. in color)
- ISBN
- 9783319237541
- 9783319237534 (print ed.)
- Subjects (MeSH)
- Autoimmune Diseases
- Pemphigoid, Bullous
- Pemphigus
- Skin Diseases, Vesiculobullous - diagnosis
- Skin Diseases, Vesiculobullous - immunology
- Abstract
- This book provides a quick study and reference guide for physicians who treat patients with autoimmune bullous diseases (AIBDs), the most life-threatening inflammatory diseases of the skin. AIBDs are rare, and comprise less than 1% of the dermatological patients. As such, they are often given little focus in general dermatology literature, despite being complicated and demanding diseases . Autoimmune Bullous Diseases Study Guide: Text and Review is written in direct and simple diction with tables and figures to practically illustrate this difficult field. At the end of each chapter the reader is challenged to check the learned matter with multiple-choice questions. It contains protocols and follows international guidelines, making it suitable study material for courses on autoimmune bullous diseases. Residents and researchers in dermatology and adjacent disciplines will find this book useful as a quick guide when dealing with these patients.
- Contents
- Part I. Immunology and Diagnostic Tests -- 1 Basic Principles of the Immune System and Autoimmunity -- 2 Dermatological Examination of Bullous Diseases -- 3 How to Take a Biopsy -- 4 Direct Immunofluorescence Microscopy -- 5 Indirect Immunofluorescence Microscopy -- 6 Immunoassays -- Part II. Pemphigus -- 7 Structure of Desmosomes -- 8 Pemphigus Vulgaris -- 9 Pemphigus Foliaceus -- 10 Paraneoplastic Pemphigus -- 11 IgA Pemphigus -- 12 Drug-Induced Pemphigus -- Part III. Pemphigoids -- 13 Structure of Hemidesmosomes and the Epidermal Basement Membrane Zone -- 14 Cutaneous Pemphigoid -- 15 Mucous Membrane Pemphigoid -- 16 Epidermolysis Bullosa Acquisita -- 17 Bullous Systemic Lupus Erythematosus -- 18 Linear IgA Disease -- 19 Drug-Induced Pemphigoid and Linear IgA Disease -- Part IV. Other Inflammatory Bullous Diseases -- 20 Dermatitis Herpetiformis -- 21 Stevens–Johnson Syndrome/Toxic Epidermal Necrolysis and Erythema Exsudativum Multiforme -- 22 Porphyria Cutanea Tarda and Pseudoporphyria -- 23 Bullous Dermatitis Artefacta -- Part V. Resources -- 24 Patient Support Groups and International Centers for AIBD.
- Format
- e-Book
- Location
- Online
Autoimmune Disease : Pathogenesis, Genetics, Immunotherapy, Prophylaxis and Principles for Organ Transplantation
https://libcat.nshealth.ca/en/permalink/provcat40853
Duncan Dartrey Adams, Christopher Dartrey Adams.
--Dordrecht:
Springer
, c2013.
- Available Online
- View e-Book
- Location
- Online
This book describes how the Jerne-Burnet Forbidden Clone Theory and the Adams-Knight H Gene Theory, solved the pathogenesis and genetics of the autoimmune diseases showing how specific immunotherapy and prophylaxis can be developed. Furthermore, Ebringer's discovery of two microbial triggers of autoimmune diseases is described and the conclusion drawn that all autoimmune diseases have microbial triggers, so will be preventable by the finding of the triggers and vaccination against them.
- Available Online
- View e-Book
- Author
- Adams, Duncan Dartrey
- Other Authors
- Adams, Christopher Dartrey
- Responsibility
- Duncan Dartrey Adams, Christopher Dartrey Adams
- Place of Publication
- Dordrecht
- Publisher
- Springer
- Date of Publication
- c2013
- Physical Description
- 1 online resource (xiii, 58 p. : 21 illus., 10 illus. in color)
- Series Title
- SpringerBriefs in public health
- ISBN
- 9789400769373
- 9789400769366 (print ed.)
- ISSN
- 2192-3698
- Subjects (MeSH)
- Autoimmune Diseases - etiology
- Autoimmune Diseases - history
- Abstract
- This book describes how the Jerne-Burnet Forbidden Clone Theory and the Adams-Knight H Gene Theory, solved the pathogenesis and genetics of the autoimmune diseases showing how specific immunotherapy and prophylaxis can be developed. Furthermore, Ebringer's discovery of two microbial triggers of autoimmune diseases is described and the conclusion drawn that all autoimmune diseases have microbial triggers, so will be preventable by the finding of the triggers and vaccination against them.
- Contents
- Discovery -- Pathogenesis -- Genetics -- Microbial Triggers -- Immunotherapy -- Prophylaxis -- Transplantation.
- Format
- e-Book
- Location
- Online
The autoimmune diseases
https://libcat.nshealth.ca/en/permalink/provcat33140
edited by Noel R. Rose and Ian R. Mackay.
(6th ed.)
--London, UK:
Elsevier
, c2020.
- Available Online
- View e-Book
- Access
- Registration required for PDF access.
- Location
- Online
- Available Online
- View e-Book
- Other Authors
- Mackay, Ian R.
- Rose, Noel R.
- Responsibility
- edited by Noel R. Rose and Ian R. Mackay
- Edition
- 6th ed.
- Place of Publication
- London, UK
- Publisher
- Elsevier
- Date of Publication
- c2020
- Physical Description
- 1 online resource
- ISBN
- 9780128121023
- Subjects (MeSH)
- Autoimmune Diseases
- Access
- Registration required for PDF access.
- Format
- e-Book
- Location
- Online
Autoimmune Diseases : Acute and Complex Situations
https://libcat.nshealth.ca/en/permalink/provcat28030
edited by Munther A. Khamashta, Manuel Ramos-Casals.
--London:
Springer-Verlag
, c2011.
- Available Online
- View e-Book
- Location
- Online
- Available Online
- View e-Book
- Author
- Khamashta, Munther A
- Other Authors
- Ramos-Casals, Manuel
- Responsibility
- edited by Munther A. Khamashta, Manuel Ramos-Casals
- Place of Publication
- London
- Publisher
- Springer-Verlag
- Date of Publication
- c2011
- ISBN
- 9780857293589
- Subjects (LCSH)
- Immunology
- Critical care medicine
- Format
- e-Book
- Location
- Online
Autoimmune Diseases in Endocrinology
https://libcat.nshealth.ca/en/permalink/provcat28275
edited by Anthony P. Weetman.
--Totowa, NJ:
Humana Press
, c2008.
- Available Online
- View e-Book
- Location
- Online
- Available Online
- View e-Book
- Author
- Weetman, Anthony P
- Responsibility
- edited by Anthony P. Weetman
- Place of Publication
- Totowa, NJ
- Publisher
- Humana Press
- Date of Publication
- c2008
- Series Title
- Contemporary endocrinology (Totowa, N.J.)
- ISBN
- 9781597455176
- Subjects (MeSH)
- Autoimmune Diseases
- Autoimmunity
- Endocrine System Diseases
- Subjects (LCSH)
- Endocrinology
- Immunology
- Format
- e-Book
- Location
- Online
Autoimmune Diseases of the Skin : Pathogenesis, Diagnosis, Management
https://libcat.nshealth.ca/en/permalink/provcat28743
edited by Michael Hertl.
(3rd rev. and enlarged ed.)
--Vienna:
Springer-Verlag
, c2011.
- Available Online
- View e-Book
- Location
- Online
- Available Online
- View e-Book
- Author
- Hertl, Michael
- Responsibility
- edited by Michael Hertl
- Edition
- 3rd rev. and enlarged ed.
- Place of Publication
- Vienna
- Publisher
- Springer-Verlag
- Date of Publication
- c2011
- ISBN
- 9783211992258
- Subjects (MeSH)
- Autoimmune Diseases
- Skin Diseases - immunology
- Subjects (LCSH)
- Immunology
- Dermatology
- Format
- e-Book
- Location
- Online
Autoimmune diseases, The
https://libcat.nshealth.ca/en/permalink/provcat50404
Rose, Noel R.
(6th ed.)
--Philadelphia, PA:
Elsevier
, 2020.
- Available Online
- View e-Book
- Location
- Online
- Available Online
- View e-Book
- Author
- Rose, Noel R.
- Edition
- 6th ed.
- Place of Publication
- Philadelphia, PA
- Publisher
- Elsevier
- Date of Publication
- 2020
- ISBN
- 9780128121023
- Subjects (MeSH)
- Autoimmune Diseases
- Notes
- Access to this online resource is restricted to IWK Health Centre employees working from inside the hospital network.
- Format
- e-Book
- Location
- Online
Autoimmune (IgG4-related) Pancreatitis and Cholangitis
https://libcat.nshealth.ca/en/permalink/provcat40691
Michael J. Levy, Suresh T. Chari, editors.
--New York, NY:
Springer
, c2013.
- Available Online
- View e-Book
- Location
- Online
Autoimmune (IgG4-related) Pancreatitis and Cholangitis reviews the breadth of clinical, imaging, histological, laboratory, and imaging features associated with IgG4-associated systemic disease, especially AIP and IAC. Written by experts in their fields, each chapter includes an overview of existing data as well as the most up-to-date scientific information and emerging data. The book also addresses areas of uncertainty and controversy, briefly highlighting clinical and research needs relative t…
- Available Online
- View e-Book
- Other Authors
- Levy, Michael J
- Chari, Suresh T
- Responsibility
- Michael J. Levy, Suresh T. Chari, editors
- Place of Publication
- New York, NY
- Publisher
- Springer
- Date of Publication
- c2013
- Physical Description
- 1 online resource (xi, 265 p. : 121 illus., 72 illus. in color)
- ISBN
- 9781441964304
- 9781441964298 (print ed.)
- Subjects (MeSH)
- Autoimmune Diseases
- Cholangitis
- Immunoglobulin G
- Pancreatitis
- Abstract
- Autoimmune (IgG4-related) Pancreatitis and Cholangitis reviews the breadth of clinical, imaging, histological, laboratory, and imaging features associated with IgG4-associated systemic disease, especially AIP and IAC. Written by experts in their fields, each chapter includes an overview of existing data as well as the most up-to-date scientific information and emerging data. The book also addresses areas of uncertainty and controversy, briefly highlighting clinical and research needs relative to the respective topic. Comprehensive and easy to use, Autoimmune (IgG4-related) Pancreatitis and Cholangitis is a valuable resource for physicians who deal with or are interested in these complex disease processes, including gastroenterologists, hepatologists, and surgeons.
- Contents
- Background and Perspective -- Part I. Autoimmune Pancreatitis -- Immune Pathogenesis -- Overview of Types 1 and 2 -- Histologic Features -- CT and MRI Features -- EUS Features -- ERCP Features -- Clinical Features -- Approach to Diagnosis -- Surgical Implications -- Approach to Therapy -- Part II. IgG4-Related Sclerosing Cholangitis -- Secondary Sclerosing Cholangitis -- Histologic Features -- CT and MRI Features -- ERCP and EUS/IDUS Features -- Clinical Spectrum and Management -- Part III. Other Organ Involvement -- Overview -- Tubulointerstitial Nephritis and other Renal Involvement by IgG4-Related Disease -- IgG4-related Lung Disease -- Part IV. World-Wide Experience with AIP and IgG4-Related Sclerosing Cholangitis -- Italian Experience -- British Experience -- Japanese Experience -- Korean Experience -- Summary and Look to the Future.
- Format
- e-Book
- Location
- Online
Autoimmune pancreatitis
https://libcat.nshealth.ca/en/permalink/provcat33944
Terumi Kamisawa, Jae Bock Chung, editors.
--Heidelberg:
Springer
, c2015.
- Available Online
- View e-Book
- Location
- Online
- Available Online
- View e-Book
- Other Authors
- Kamisawa, Terumi
- Chung, Jae Bock
- Responsibility
- Terumi Kamisawa, Jae Bock Chung, editors
- Place of Publication
- Heidelberg
- Publisher
- Springer
- Date of Publication
- c2015
- Physical Description
- 1 online resource (xii, 209 pages)
- ISBN
- 9783642550867 (electronic bk.)
- 9783642550850
- Subjects (MeSH)
- Autoimmune Diseases
- Pancreatitis
- Subjects (LCSH)
- Pancreatitis
- Pancreatitis - Diagnosis
- Pancreatitis - Treatment
- Contents
- Part I. Introduction, Epidemiology and Pathology -- 1. Overview of Type 1 and Type 2 AIP -- 2. Epidemiology of Autoimmune Pancreatitis -- 3. Pathophysiology of Autoimmune Pancreatitis -- 4. Pathology -- 5. Pancreatic Endocrine and Exocrine Functions in Patients with Autoimmune Pancreatitis -- 6. Type 2 AIP -- Part II. Diagnosis -- 7. Diagnostic Criteria of Autoimmune Pancreatitis -- 8. Clinical Features -- 9. Serology -- 10. Abdominal Ultrasonography -- 11. Imaging Findings: CT and MRI with MRCP -- 12. Endoscopy: ERCP and EUS -- 13. A Role of PET/CT in the Diagnosis of Autoimmune Pancreatitis -- 14. Tissue Acquisition for Histologic Diagnosis -- Part III. Other Organ Involvements -- 15. IgG4-Related Sclerosing Cholangitis -- 16. Sialadenitis and Dacryoadenitiss: IgG4-Related Mikulicz’s Disease Would Precede Autoimmune Pancreatitis and Be Likely to Relapse -- 17. Retroperitoneal Fibrosis -- 18. Renal Lesions -- 19. Pulmonary Lesions -- 20. Lymphadenopathy -- 21. IgG4-Related Gastrointestinal Lesion -- Part IV. Treatment and Prognosis -- 22. Steroid Therapy for Autoimmune Pancreatitis -- 23. Treatment: Immunomodulatory Drugs and Rituximab -- 24. Treatment of Relapsed Autoimmune Pancreatitis -- 25. Development to Chronic Pancreatitis -- 26. Occurrence of Malignant Neoplasms -- Part V. AIP in the World -- 27. International Survey of Autoimmune Pancreatitis -- 28. Autoimmune Pancreatitis in the USA -- 29. Autoimmune Pancreatitis in Europe -- Part VI. Future Perspective -- 30. Future Perspective.
- Format
- e-Book
- Location
- Online
Auto-Inflammatory Syndromes : Pathophysiology, Diagnosis, and Management
https://libcat.nshealth.ca/en/permalink/provcat44069
Petros Efthimiou, editor.
--Cham:
Springer
, 2019.
- Available Online
- View e-Book
- Location
- Online
This book provides an overview of auto-inflammatory syndromes, covering the underlying immune mechanisms that lead to their development, specific disease presentations, and clinical treatment guidelines. The book is divided into two sections, adult and pediatric, with chapters focusing on individuals diseases such as systemic arthritis, hyper-IgD, pap syndrome, idiopathic recurrent pericarditis, and familial Mediterranean fever. Chapters incorporate the most recent advances in disease pathophys…
- Available Online
- View e-Book
- Other Authors
- Efthimiou, Petros
- Responsibility
- Petros Efthimiou, editor
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- 2019
- Physical Description
- 1 online resource (xix, 322 p.) : 39 illus., 31 illus. in color
- ISBN
- 9783319969299
- 9783319969282 (Print ed.)
- 9783319969305 (Print ed.)
- Subjects (MeSH)
- Autoimmune Diseases
- Hereditary Autoinflammatory Diseases
- Inflammation - physiopathology
- Specialty
- Allergy and Immunology
- Abstract
- This book provides an overview of auto-inflammatory syndromes, covering the underlying immune mechanisms that lead to their development, specific disease presentations, and clinical treatment guidelines. The book is divided into two sections, adult and pediatric, with chapters focusing on individuals diseases such as systemic arthritis, hyper-IgD, pap syndrome, idiopathic recurrent pericarditis, and familial Mediterranean fever. Chapters incorporate the most recent advances in disease pathophysiology and examine the underlying inductive and effector mechanisms and therapies that relate to each auto-inflammatory disorder at the genetic, molecular, cellular, and epidemiologic levels. The book also discusses the research behind auto-inflammatory disorders to offer detailed clinical guidelines regarding diagnostic techniques, treatment plans, and advice on how to best transition pediatric patients into adult treatment. This is an invaluable reference on auto-inflammatory syndromes for clinicians and researchers in pediatric and adult rheumatology and immunology.
- Contents
- 1. Immunology of Auto-inflammatory Syndromes -- Part I. Monogenic Autoinflammatory Diseases -- 2. Mevalonate Kinase Deficiency (MKD)/Hyperimmunoglobulin D Syndrome (HIDS) -- 3. The TNF Receptor-Associated Autoinflammatory Syndrome (TRAPS) -- 4. PAPA Syndrome and the Spectrum of PSTPIP1-Associated Inflammatory Diseases -- 5. Blau Syndrome -- 6. Deficiency of the Interleukin-1 Receptor Antagonist (DIRA) -- 7. Deficiency of the Interleukin-36 Receptor Antagonist (DITRA) and Generalized Pustular Psoriasis -- 8. Cryopyrin-Associated Periodic Syndromes (CAPS) -- 9. Familial Mediterranean Fever -- 10. Type I Interferonopathies: From Pathophysiology to Clinical Expression -- 11. Deficiency of Adenosine Deaminase 2 (DADA2) -- 12. Yao Syndrome -- Part II. Polygenic Autoinflammatory Diseases -- 13. Systemic Juvenile Idiopathic Arthritis -- 14. Macrophage Activation Syndrome (MAS) -- 15. Schnitzler Syndrome -- 16. Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Cervical Adenitis (PFAPA) Syndrome -- 17. Chronic Nonbacterial Osteomyelitis -- 18. Improving the Transition from Pediatric to Adult Care for Adolescents and Young Adults with Autoinflammatory Diseases -- 19. Adult-Onset Still’s Disease - 20. Idiopathic Recurrent Acute Pericarditis -- 21. Adamantiades-Behçet’s Disease -- 22. Amyloidosis.
- Format
- e-Book
- Location
- Online
Clinical cases in autoimmune blistering diseases
https://libcat.nshealth.ca/en/permalink/provcat33941
Dédée F. Murrell, editor.
--Cham, Switzerland:
Springer
, c2015.
- Available Online
- View e-Book
- Location
- Online
- Available Online
- View e-Book
- Other Authors
- Murrell, Dédée F.
- Responsibility
- Dédée F. Murrell, editor
- Place of Publication
- Cham, Switzerland
- Publisher
- Springer
- Date of Publication
- c2015
- Physical Description
- 1 online resource (xii, 166 pages)
- Series Vol.
- v. 5
- Series Title
- Clinical cases in dermatology
- ISBN
- 9783319101484 (electronic bk.)
- 9783319101477
- Subjects (MeSH)
- Autoimmune Diseases - Case Reports
- Blister - Case Reports
- Subjects (LCSH)
- Skin - Diseases - Immunological aspects - Case studies
- Contents
- 1. An Elderly Patient with a Generalized Pruritic Eruption -- 2. Confusion and Corticosteroids: 80-Year Old Woman with Pruritic Urticarial Plaques and Tense Blisters -- 3. Bullous Pemphigoid and Tetracycline -- 4. A 52-Year-Old Italian Male with Widespread Blistering and Erosions Refractory to Regular Dose Prednisone -- 5. Life-Threatening Pemphigus Vulgaris -- 6. A Crusted Plaque on the Right Cheek in a 45 Year Old Woman -- 7. A 52 Year Old Man with Cerebriform Vegetating Masses on the Scalp -- 8. Bullous Lesions on a Chronic Cutaneous Plaque -- 9. A 60-Year-Old Woman with Pemphigus Vulgaris Refractory to High-Dose Prednisone -- 10. Beware of Infection: 48-Year Old Woman with Refractory Mucocutaneous Blisters -- 11. A 71-Year-Old Man with Blisters on the Face and a Painful Left Thigh -- 12. A 57 Year Old Woman with Widespread Scales and Scattered Erosions -- 13. Pemphigus Foliaceus, var. Herpetiformis and Sulphonamide -- 14. A 43 Year Old with Vegetative Plaques and Erosions on the Trunk -- 15. Dermatitis Herpetiformis -- 16. A Healthy African Child with Blisters -- 17. Case Report: An 11 Year-Old Girl with Blisters -- 18. A Man with a Blistering Rash -- 19. A Chronically Ill Teenager with Blisters and Scars -- 20. Detached Epidermis in an Adult Female -- 21. Single Step Multivariant Analysis of Serum Autoantibodies in Autoimmune Blistering Diseases Using BIOCHIP® Mosaic Technology -- 22. Desquamative Gingivitis Refractory to Conventional Treatments in a Young Female Desiring to Have a Child.
- Format
- e-Book
- Location
- Online
Clinical Neuroimmunology : Multiple Sclerosis and Related Disorders
https://libcat.nshealth.ca/en/permalink/provcat44800
Syed A. Rizvi, Jonathan F. Cahill, Patricia K. Coyle, editors.
(Second edition)
--Cham:
Humana Press
, c2020.
- Available Online
- View e-Book
- Location
- Online
This comprehensive, up-to-date book is designed to make recent developments in neuroimmunology accessible to medical professionals in the field. The field of neuroimmunology is complex and rapidly evolving, especially with the current improvements in targeted biologic therapies. This resource concisely offers clear explanations of these scientific and clinical advancements. Divided into five parts, the book begins with an in-depth introduction to neuroimmunology and the principles of immunother…
- Available Online
- View e-Book
- Other Authors
- Rizvi, Syed A.
- Cahill, Jonathan F.
- Coyle, Patricia K.
- Responsibility
- Syed A. Rizvi, Jonathan F. Cahill, Patricia K. Coyle, editors
- Edition
- Second edition
- Place of Publication
- Cham
- Publisher
- Humana Press
- Date of Publication
- c2020
- Physical Description
- 1 online resource (xiii, 353 p.) : 46 illus., 22 illus. in color
- Series Title
- Current clinical neurology
- ISBN
- 9783030244361
- 9783030244354 (Print ed.)
- 9783030244378 (Print ed.)
- 9783030244385 (Print ed.)
- ISSN
- 1559-0585
- Subjects (MeSH)
- Autoimmune Diseases of the Nervous System - immunology
- Multiple Sclerosis - immunology
- Specialty
- Allergy and Immunology
- Neurology
- Abstract
- This comprehensive, up-to-date book is designed to make recent developments in neuroimmunology accessible to medical professionals in the field. The field of neuroimmunology is complex and rapidly evolving, especially with the current improvements in targeted biologic therapies. This resource concisely offers clear explanations of these scientific and clinical advancements. Divided into five parts, the book begins with an in-depth introduction to neuroimmunology and the principles of immunotherapy. Section two consists of eight chapters devoted to multiple sclerosis, including discussions on the clinical features of the disease as well as symptom management and diagnosis. Subsequent chapters then dive into other central nervous system inflammatory disorders such as neuromyelitis optica, autoimmune encephalopathies, and immunological aspects of cancer. Following this are two chapters that examine distinct aspects of autoimmune disorders of the peripheral nervous system. Finally, the book closes with a review on the neurologic manifestations, diagnostic approaches and treatments of the various systemic rheumatic diseases. Following its successful predecessor edition, Clinical Neuroimmunology: Multiple Sclerosis and Related Disorders, Second Edition is positioned to be an invaluable asset to neurologists, residents and fellows, internists, and general practitioners who treat patients with neurologic disorders and other systemic autoimmune diseases.
- Contents
- Part 1. Introduction -- 1. Introduction to Neuroimmunology -- 2. Principles of Immunotherapy -- Part II. Multiple Sclerosis -- 3. Immunopathogenesis -- 4. Epidemiology and Genetics -- 5. Clinical Features, Symptom Management, and Diagnosis -- 6. Magnetic Resonance Imaging and Analysis in Multiple Sclerosis -- 7. Disease-Modifying Agents -- 8. Clinical Decision-Making in the Management of Multiple Sclerosis -- 9. Multiple Sclerosis in Children -- 10. Vitamin D and Multiple Sclerosis -- Part III .Other CNS inflammatory Disorders -- 11. Acute Disseminated Encephalomyelitis -- 12. Neuromyelitis Optica Spectrum Disorders -- 13. Paraneoplastic and Other Autoimmune Disorders -- 14. Adult and Childhood Vasculitis of the Nervous System -- Part IV. Peripheral Nervous System Disorders -- 15. Immunologic Disorders of Neuromuscular Junction and Muscle -- 16. Autoimmune Neuropathies -- Part V Systemic Disorders -- 17. Neurologic Manifestations of Systemic Rheumatologic Diseases.
- Format
- e-Book
- Location
- Online
Clinical Neuroimmunology : Multiple Sclerosis and Related Disorders
https://libcat.nshealth.ca/en/permalink/provcat30235
edited by Syed A. Rizvi, Patricia K. Coyle.
--Totowa, NJ:
Springer Science+Business Media
, c2011.
- Available Online
- View e-Book
- Location
- Online
- Available Online
- View e-Book
- Author
- Rizvi, Syed A
- Other Authors
- Coyle, Patricia K
- Responsibility
- edited by Syed A. Rizvi, Patricia K. Coyle
- Place of Publication
- Totowa, NJ
- Publisher
- Springer Science+Business Media
- Date of Publication
- c2011
- Series Title
- Current clinical neurology
- ISBN
- 9781603278607
- Subjects (LCSH)
- Neurology
- Immunology
- Format
- e-Book
- Location
- Online
Encyclopedia of Medical Immunology
https://libcat.nshealth.ca/en/permalink/provcat44527
editors, Ian MacKay, Noel R. Rose.
--New York, NY:
Springer
, c2019.
- Available Online
- View e-Book
- Location
- Online
Offering a broad appeal to microbiologists, immunologists, and infectious disease specialists, this four volume encyclopedia covers all autoimmune, tropical, and infectious diseases. Emphasis will also be placed on genetics, physiology, metabolism, pathogenesis and applied microbiology. Under the leadership of some of the most world renowned names in the field, the encyclopedia will bring together an outstanding collection of contributions by top scientists in a variety of fields. Volumes 1-3: …
- Available Online
- View e-Book
- Other Authors
- MacKay, Ian
- Rose, Noel R.
- Responsibility
- editors, Ian MacKay, Noel R. Rose
- Place of Publication
- New York, NY
- Publisher
- Springer
- Date of Publication
- c2019
- Physical Description
- 1 online resource (approx. 1000 p.)
- Series Title
- Springer reference
- ISBN
- 9781461492092
- Subjects (MeSH)
- Autoimmune Diseases
- Communicable Diseases - immunology
- Immune System Phenomena
- Immunology
- Vaccination
- Vaccines
- Specialty
- Allergy and Immunology
- Notes
- "Living edition."
- Abstract
- Offering a broad appeal to microbiologists, immunologists, and infectious disease specialists, this four volume encyclopedia covers all autoimmune, tropical, and infectious diseases. Emphasis will also be placed on genetics, physiology, metabolism, pathogenesis and applied microbiology. Under the leadership of some of the most world renowned names in the field, the encyclopedia will bring together an outstanding collection of contributions by top scientists in a variety of fields. Volumes 1-3: Diseases will be divided by the 11 main sections of the body, namely Integumentary, Skeletal, Respiratory, Digestive, Urinary, and Reproductive. For some of the autoimmune disease, more then one system will be involved but the delineation serves to broadly break down the diseases into systems. Volume 4 will cover the vaccines for said diseases and future prospects will be offered by leaders in industry and academia. Volume 4 will also be broken down into all the body systems, as in the other two volumes. For each vaccine, for each disease, and in each system the following will be included: A list of the vaccines currently available along with a list of the companies that manufacture them; Molecular immunology of the vaccine; Type of immunity involved in protection; Mode of vaccination for each vaccine; Repeated boosters and length of immunological memory; Commercial production of vaccines; Storage of vaccines; Standardization and control of vaccines; WHO programs and world-wide disease eradication programs based upon vaccines.
- Format
- e-Book
- Publication Type
- Encyclopedia
- Location
- Online
Encyclopedia of medical immunology : autoimmune diseases
https://libcat.nshealth.ca/en/permalink/provcat33459
Ian MacKay, Noel R. Rose, editors-in-chief ; Betty Diamond, Anne Davidson, editors.
--New York:
Springer Reference
, c2014.
- Available Online
- View e-Book
- Location
- Online
Different from other resources, this volume offers a broad appeal to microbiologists, immunologists, and infectious disease specialists on Autoimmune Diseases. The volume covers topics such as skin and alopecia, Kidney, Liver, Paraneoplastic, Resolution of inflammation, Cardiovascular/systemic inflammation and atherosclerosis, Gut, Regulatory lymphocytes T, B, other and Rheumatic Disease. The volume is written by internationally renowned authors who are authorities in their respective fields.
- Available Online
- View e-Book
- Other Authors
- Mackay, Ian M
- Rose, Noel R
- Diamond, Betty
- Davidson, Anne
- Responsibility
- Ian MacKay, Noel R. Rose, editors-in-chief ; Betty Diamond, Anne Davidson, editors
- Alternate Title
- Encyclopedia of medical immunology. Vol. 1 & 2, Autoimmune diseases
- Autoimmune diseases
- Place of Publication
- New York
- Publisher
- Springer Reference
- Date of Publication
- c2014
- Physical Description
- 1 online resource (xliii, 1296 pages)
- ISBN
- 9780387848280 (electronic bk.)
- 9780387848273
- Subjects (LCSH)
- Autoimmune diseases - Encyclopedias
- Abstract
- Different from other resources, this volume offers a broad appeal to microbiologists, immunologists, and infectious disease specialists on Autoimmune Diseases. The volume covers topics such as skin and alopecia, Kidney, Liver, Paraneoplastic, Resolution of inflammation, Cardiovascular/systemic inflammation and atherosclerosis, Gut, Regulatory lymphocytes T, B, other and Rheumatic Disease. The volume is written by internationally renowned authors who are authorities in their respective fields.
- Contents
- B cell development and repertoire sel: B cell central tolerance: controlling self-reactive B cells in the bone marrow -- B cell tolerance -- B cell trafficking -- B1 cells -- BCR signaling -- CS and SHM -- MZB cells -- Plasma Cells -- Regulatory B cells -- Repertoire selection -- TFH help -- Cardiovascular/systemic inflammation: Atherosclerosis and cytokines.-Autoantibodies and atherosclerosis -- Autoantibodies to endothelial cells -- Autoimmune disease and premature atherosclerosis -- Autoimmune heart disease animal models -- Autoimmune myocarditis and pericarditis -- Cell adhesion molecules -- Dendritic cells and atherosclerosis -- Endothelial cells and inflammation -- Immune mediated mechanisms of the metabolic syndrome -- Lymphocytes in Atherosclerosis -- Macrophages, Oxidative stress and Atherosclerosis -- Mechanisms of endothelial activation -- Neutrophils in endothelial damage -- Platelets, atherosclerosis and immunity -- Viral myocarditis -- Gut: Celiac disease -- Overview of the Gut microbiome -- Overview on IBD -- Overview on mucosal immunity -- Liver: Adaptive immune cells in the liver -- AIH: clinical + systemic manifestations and treatment -- AIH: Pathogenesis, association with other syndromes -- Animal models of AIH -- Animal models of hepatitis B and C -- Gestational Alloimmune Liver Disease -- Immune response during acute and chronic Hepatitis B -- Immune response during acute and chronic Hepatitis C -- Immunosuppression in clinical liver transplantation -- Innate immune cells in the liver -- KC and tolerance -- Liver transplantation tolerance in animal models -- Liver vasculature and microvasculature -- LSEC and tolerance -- PBC genetics -- PBC: clinical + systemic manifestations and treatment -- Primary T Cell activation in the liver -- PSC: clinical + systemic manifestations and treatment -- The hepatic lymphatic system -- Transplantation for auto immune diseases -- Transplantation for chronic viral hepatitis -- Tregs in the liver -- Ultrastructure of the liver sinusoid -- Lymphocytes activation T, B, NK: B7/CD28 family -- Bcl-2 family -- CD40 -- CD5 -- Chemokines -- CTLA4-Ig -- Cytotoxic T cells -- FcRIIb -- GTPases -- IL-21 -- Interleukin 6 -- LAT -- mTOR -- NFAT -- NFkB -- NK cell activation -- PI3K -- PKCtheta -- PTPN22 -- Rho/Rac GTPases -- SHIP -- T cell memory -- Paraneoplastic: Cancer and dermatomyositis -- Cancer and Fever -- Cancer and joint pain -- Cancer and nephrotic syndrome -- Cancer and neuropathies -- Cancer and the CNS -- Cancer and thrombosis -- Cancer therapies and autoimmunity -- Paraneoplastic Syndromes, an overview -- Tumor Infiltrating T cells -- Tumor Macrophages -- Resolution of Inflammation: Anti-oxidants -- CD5 -- CTLA 4 -- EICOSANOIDS (prostaglandins, leucotrienes, and related compounds) -- Fas/fas ligand -- Fibrosis -- Nitric oxide -- Polymorphonuclear Leucocytes (PMN)/neutrophils -- Resolution of Inflammation -- TGFbeta -- Kidney: Anti-GBM GN -- Autoimmune disease -- Autoimmune Kidney Disease and Pregnancy -- Autoimmunity and Inflammation in Diabetic Nephropathy -- Complement regulation in the Kidney -- IgA Nephropathy -- Immune System and the Kidney -- Impact of Recurrent Autoimmune Diseases in Renal Transplant Outcomes -- Indications for Biopsy in Autoimmune GN -- Pathogenesis of Lupus Nephritis and New Approaches to Treatment -- Proteinuric Kidney Diseases: Importance of Blood Pressure Control -- Scleroderma Renal Crisis -- Spectrum of Minimal Change Disease to Focal Segmental Glomerulosclerosis -- Translational aspects of MN -- TTP and the Kidney -- Vasculitits and the Kidney (ANCA, etc) -- Regulatory lymphocytes T, B, other: Regulatory B cells -- Tregs: Regulatory T cells -- Rheumatic Disease: APLS- Mechanism of thrombosis -- APLS- treatment -- APLS-Clinical Manifestations -- Autoinflammatory Syndromes -- Complement in rheumatic diseases -- Diagnosis and Treatment of Lupus Nephritis -- Environment and autoimmunity -- Epigenetics in autoimmunity -- Immunodeficiency in Autoimmune diseases -- Juvenile diseases: Arthritis treatment in children (incl. pathogenesis, presentation & treatment) -- Juvenile diseases: Genetics of JIA -- Juvenile diseases: Juvenile arthritis syndromes -- Juvenile diseases: Kawasaki syndrome -- Juvenile diseases: SLE-children -- microRNA in autoimmunity -- Myositis pathogenesis -- Myositis-Dermatomyositis, Polymyositis, inclusion body myositis, and autoantibodies -- Myositis: Juvenile myositis -- Nephritogenic autoantibodies in SLE -- RA- clinical features -- RA- extraarticular manifestations -- RA-animal models -- RA-autoantibodies -- RA-genetics -- RA-treatment -- RA: Biologics in the treatment of RA -- RA: Small molecules -- Raynauds phenomenon -- Sarcoidosis -- Scleroderma-genetics -- Scleroderma: Pathogenesis and Clinical Manifestations -- Sjogren's syndrome -- SLE -- Clinical Trials in SLE -- SLE -- Discoid SLE -- SLE -- Novel targets in SLE Essay -- SLE-animal models -- SLE-autoantibodies -- SLE-clinical features and diagnosis -- SLE-gender and hormonal influences -- SLE-genetics -- SLE-pathogenesis -- SLE-pregnancy -- SLE-skin -- SLE-treatment -- SLE: Congenital heart block and neonatal lupus -- SLE: Mixed connective tissue disease (MCTD) -- Spondyloarthritis: Ankylosing Spondylitis -- Spondyloarthritis: Psoriatic arthritis -- Spondyloarthritis: Reactive Arthritis -- Treatment (current and upcoming) of scleroderma -- Vasculitis: Bechets -- Vasculitis: Churg-Strauss syndrome.-Vasculitis: Cutaneous vasculitis (hypersensitivity vasculitis) -- Vasculitis: Giant cell arteritis.-Vasculitis: Henoch-Schonlein purpura -- Vasculitis: Microscopic polyangiitis -- Vasculitis: Polyarteritis nodosa -- Vasculitis: Polymyalgia rheumatica -- Vasculitis: Primary CNS vasculitis.-Vasculitis: Wegenerâ??s granulomatosis -- Skin and Alopecia: Alopecia areata -- Autoimmune Blistering Diseases -- Blistering diseases: Bullous Pemphigoid -- Blistering diseases: Mucous Membrane Pemphigoid -- Blistering diseases: Linear IgA disease (LAD) -- Blistering diseases: Pemphigus -- Dermatomyositis -- Erythema nodosum -- Hair Loss In Lupus Erythematosus -- Inflammatory -- SLE ? Skin -- Inflammatory: Dermatomyositis ? skin -- Inflammatory: Discoid lupus -- Inflammatory: psoriasis cutaneous -- Lichen Planopilaris -- Lichen planus -- Neutrophilic dermatoses: Sweets syndrome -- Neutrophilic dermatoses: Leukocytoclastic vasculitis -- Neutrophilic dermatoses: Pyoderma gangrenosum -- Scleroderma like conditions -- Skin and Alopecia -- Vitiligo.
- Format
- e-Book
- Location
- Online
Genetics of Rare Autoimmune Diseases
https://libcat.nshealth.ca/en/permalink/provcat44453
Javier Martín, Francisco David Carmona, editors.
--Cham:
Springer
, c2019.
- Available Online
- View e-Book
- Location
- Online
The main aim of this volume is to provide an updated overview of the genetic basis of a group of complex disorders that are considered rare individually, but show a relatively high prevalence on the whole in developed countries: the rare autoimmune diseases. These are chronic disorders that involve long and expensive treatments with considerable side effects that may dramatically reduce the quality of life of affected people. Therefore, shedding light into their pathologic mechanisms is a major…
- Available Online
- View e-Book
- Other Authors
- Martín, Javier
- Carmona, Francisco David
- Responsibility
- Javier Martín, Francisco David Carmona, editors
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2019
- Physical Description
- 1 online resource (viii, 240 p.) : 12 illus., 10 illus. in color
- Series Title
- Rare diseases of the immune system
- ISBN
- 9783030039349
- 9783030039332 (Print ed.)
- 9783030039356 (Print ed.)
- ISSN
- 2282-6505
- Subjects (MeSH)
- Autoimmune Diseases - genetics
- Rare Diseases - genetics
- Specialty
- Allergy and Immunology
- Genetics, Medical
- Abstract
- The main aim of this volume is to provide an updated overview of the genetic basis of a group of complex disorders that are considered rare individually, but show a relatively high prevalence on the whole in developed countries: the rare autoimmune diseases. These are chronic disorders that involve long and expensive treatments with considerable side effects that may dramatically reduce the quality of life of affected people. Therefore, shedding light into their pathologic mechanisms is a major concern given their growing social and economic awareness and impact. General sections include different chapters on single entities as systemic lupus and sclerosis, Behçet’s disease, Sjogren’s syndrome and polymiositis, and sections devoted to autoimmune vasculitis, hepatic autoimmune conditions, as well as those affecting the nervous system, and a concluding chapter in which the shared predisposition amongst all diseases is discussed. All the chapters are given a homogeneous scheme in which the authors explain the clinical singularities of every disease and report the recent breakthrough discoveries related to them, giving a critical interpretation and suggesting future perspectives. All contributors are renowned researchers with high expertise in each disease. Due to the exponential increase in our understanding of the genetic causes of these complex diseases, a major advance in biomedical discovery is taking place. However, most of the achievements in this field are very recent and there is a lack of bibliography gathering them together. This book is thus filling a gap and will prove a useful companion to clinicians in the first place (internists, rheumatologists, clinical immunologists, and hematologists) but also to basic and applied researchers.
- Contents
- 1. Systemic Lupus Erythematosus -- 2. Systemic Sclerosis -- 3. Behçet’s Disease -- 4 Sjögren’s Syndrome -- 5. Polymyositis/Dermatomyositis -- 6. ANCA-Associated Vasculitis -- 7. Giant Cell Arteritis -- 8. Takayasu Arteritis -- 9. Primary Biliary Cirrhosis, Primary Sclerosing Cholangitis, and Autoimmune Hepatitis -- 10. Genetics of Multiple Sclerosis -- 11. Autoimmune Myasthenia Gravis -- 12. Common Genetic Component in Autoimmunity.
- Format
- e-Book
- Location
- Online
Identifying Novel Inborn Errors of the Immune System : Primary Immunodeficiencies with Defective Class Switch and Autoimmunity
https://libcat.nshealth.ca/en/permalink/provcat41870
Elisabeth Salzer.
--Wiesbaden:
Springer
, 2017.
- Available Online
- View e-Book
- Location
- Online
In her study Elisabeth Salzer describes three novel monogenic diseases. For CD27 deficiency Elisabeth Salzer describes a large cohort of patients. Although all patients shared the same causative missense mutation, they displayed diverse clinical presentations. In another patient she was able to identify a mutation in PRKCD resulting in a primary immunodeficiency with severe Lupus-like autoimmunity. The patient exhibited increased mRNA levels of IL6. Therefore, treatment with Tocilizumab, a huma…
- Available Online
- View e-Book
- Author
- Salzer, Elisabeth
- Responsibility
- Elisabeth Salzer
- Place of Publication
- Wiesbaden
- Publisher
- Springer
- Date of Publication
- 2017
- Physical Description
- 1 online resource (xxiii, 76 pages) : 11 illus.
- Series Title
- BestMedDiss
- ISBN
- 9783658167967
- 9783658167950 (print ed.)
- Subjects (MeSH)
- Autoimmune diseases - genetics
- Genetic Diseases, Inborn - diagnosis
- Immune System Phenomena - genetics
- Notes
- Dissertation, Medical University of Vienna, 2015.
- Abstract
- In her study Elisabeth Salzer describes three novel monogenic diseases. For CD27 deficiency Elisabeth Salzer describes a large cohort of patients. Although all patients shared the same causative missense mutation, they displayed diverse clinical presentations. In another patient she was able to identify a mutation in PRKCD resulting in a primary immunodeficiency with severe Lupus-like autoimmunity. The patient exhibited increased mRNA levels of IL6. Therefore, treatment with Tocilizumab, a humanized anti-IL-6 receptor monoclonal antibody was suggested. In a family with a history of deaths due to inflammatory bowel disease she identified a missense mutation in IL21. She produced wild type and mutated IL-21 protein and demonstrated a loss of function phenotype. As IL-21 is in clinical trials, she proposed a potentially curative treatment option. These discoveries contributed to the understanding of the multifaceted regulatory mechanisms of the immune system and highlighted essential players in these complex signaling networks.
- Contents
- CD27 Deficiency-Description of a Large Patient Cohort -- PRKCD Deficiency with Lupus-Like Autoimmunity -- IL-21 Deficiency Results in Very Early-Onset Inflammatory Bowel Disease.
- Format
- e-Book
- Location
- Online
