Biologic and Systemic Agents in Dermatology
https://libcat.nshealth.ca/en/permalink/provcat42888
edited by Paul S. Yamauchi.
--Cham:
Springer
, c2018.
- Available Online
- View e-Book
- Location
- Online
Written by leading experts in the field and designed for dermatologists and residents, this book includes evidence-based medicine that underscores the clinical data, as well as practical tips on how to use both biologic and systemic agents in the field of dermatology. In the past decade, there have been several groundbreaking advances in medical dermatology. Novel biologic and systemic agents have been developed to treat inflammatory disorders, including psoriasis and atopic dermatitis, as well…
- Available Online
- View e-Book
- Other Authors
- Yamauchi, Paul S.
- Responsibility
- edited by Paul S. Yamauchi
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2018
- Physical Description
- 1 online resource (xvii, 574 p.) : 95 illus., 92 illus. in color
- ISBN
- 9783319668840
- 9783319668833 (print ed.)
- 9783319668857 (print ed.)
- 9783319883373 (print ed.)
- Subjects (MeSH)
- Anti-Infective Agents - therapeutic use
- Biological Factors - therapeutic use
- Biological Products - therapeutic use
- Dermatologic Agents - therapeutic use
- Skin Diseases - drug therapy
- Specialty
- Dermatology
- Pharmacology
- Abstract
- Written by leading experts in the field and designed for dermatologists and residents, this book includes evidence-based medicine that underscores the clinical data, as well as practical tips on how to use both biologic and systemic agents in the field of dermatology. In the past decade, there have been several groundbreaking advances in medical dermatology. Novel biologic and systemic agents have been developed to treat inflammatory disorders, including psoriasis and atopic dermatitis, as well as skin malignancies such as melanoma. Biologic and Systemic Agents in Dermatology encompasses these developments by describing the mechanism of action of these various agents and the clinical efficacy and safety to treating these respective disorders. The utilization of biologic and systemic agents in other dermatologic conditions, pharmacoeconomics, pharmacovigilance, and clinical trials outcomes are discussed as well as topics including tumor necrosis, conventional systemic agents for psoriatic disease, and oral agents for atopic dermatitis.
- Contents
- History of Therapies in Dermatology. Past to Present -- Validated scoring systems -- Interpreting Clinical Trial Data -- Compliance and Persistency -- Quality of Life in the Dermatology Practice -- Medical Legal Issues with Biologic Agents in the Treatment of Psoriasis -- Patient and Physician Perspectives on Traditional Systemic and Biologic Therapies for Psoriasis -- Outcomes of Comorbidities with Biologic and Systemic Agents -- Pharmacovigilance -- Pharmacoeconomics of Biologic Therapy in Dermatology -- Immunogenicity of Biologic Agents in Psoriasis -- Manufacturing of Biologics -- Tumor Necrosis Factor Inhibition -- Dual Inhibition of IL-12/IL- 23 and Selective Inhibition of IL-23 in Psoriasis -- Interleukin-17 Inhibition for the Treatment of Inflammatory Skin Disease -- Systemic Therapies in Psoriasis -- Nail, Scalp, and Palmoplantar Psoriasis -- Current and Emerging Treatments for Psoriatic Arthritis -- JAK Kinase Inhibitors in Dermatology -- Fumaric Acid Esters in Dermatology -- Phosphodiesterase Inhibitors for the Treatment of Inflammatory Skin Conditions -- Oral Retinoids in Dermatology -- Combination Therapy with Biologics and Other Systemic Treatments in Psoriasis -- Transitioning Biologic and Systemic Therapies in Psoriatic Patients -- Practical Considerations and Complex Cases in Psoriasis -- Biosimilars in Dermatology -- Biological Agents in Pediatric Dermatology -- Oral systemic Agents in Pediatric Dermatology -- Utilization of Biologic and Systemic Agents in the Elderly -- Miscellaneous Uses of Biologic and Systemic Agents in Other Dermatologic Conditions -- Biologics for the Treatment of Atopic Dermatitis -- Oral Agents for Atopic Dermatitis: Current and in Development -- Cutaneous T-cell lymphoma -- Anti-CD20 Agents and Potential Novel Biologics in Pemphigus Vulgaris and Other Autoimmune Blistering Diseases -- Oral Systemic Agents for Immunobullous Disorders -- Biologic and Systemic Agents in Hidradenitis Suppurativa -- Systemic and Biologic Agents for Lupus Erythematosus -- Anti-IgE Therapy in Dermatology -- Role of Intravenous Immunoglobulin in Dermatologic Disorders -- Systemic Antifungals -- Systemic Antivirals in Dermatology -- Antihelmintics in Dermatology -- Systemic Therapies for Scarring and Non-scarring alopecia -- Dapsone in Dermatology -- Systemic Non-Antibiotic Therapy in acne and rosacea -- Oral Antibiotics in Dermatology: A Practical Overview with Clinically Relevant Correlations and Management Suggestions -- Sonic Hedgehog Pathway Inhibition in the Treatment of Advanced Basal Cell Carcinoma -- Update in Immunotherapies for Melanoma -- Patient advocacy organizations.
- Format
- e-Book
- Location
- Online
Biologics in orthopaedic surgery
https://libcat.nshealth.ca/en/permalink/provcat42509
Augustus D. Mazzocca, Adam D. Lindsay.
--St. Louis, MI:
Elsevier
, c2019.
- Available Online
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- Access
- Registration required for PDF access.
- Location
- Online
Designed with the practicing clinician in mind, Biologics in Orthopaedic Surgery provides a succinct, easy-to-digest overview of the integration of biologics (platelet-rich-plasma [PRP], bone marrow aspirate [BMA], and stem cells) into today’s orthopaedic practice. Covering relevant basic science as well as clinical applications, this concise reference takes a head-to-toe approach to the emerging role of orthobiologics for specific conditions and procedures, in addition to future directions fo…
- Available Online
- View e-Book
- Author
- Mazzocca, Augusts D.
- Other Authors
- Lindsay, Adam D.
- Responsibility
- Augustus D. Mazzocca, Adam D. Lindsay
- Alternate Title
- Biologics in orthopedic surgery
- Orthopedic procedures
- Operative techniques
- Place of Publication
- St. Louis, MI
- Publisher
- Elsevier
- Date of Publication
- c2019
- Physical Description
- 1 online resource, 234 p.
- Series Title
- Operative techniques
- ISBN
- 9780323551403
- Subjects (MeSH)
- Orthopedic Procedures
- Biological Products - therapeutic use
- Specialty
- Orthopedic Procedures
- Regenerative Medicine
- Abstract
- Designed with the practicing clinician in mind, Biologics in Orthopaedic Surgery provides a succinct, easy-to-digest overview of the integration of biologics (platelet-rich-plasma [PRP], bone marrow aspirate [BMA], and stem cells) into today’s orthopaedic practice. Covering relevant basic science as well as clinical applications, this concise reference takes a head-to-toe approach to the emerging role of orthobiologics for specific conditions and procedures, in addition to future directions for implementation.
- Access
- Registration required for PDF access.
- Format
- e-Book
- Publication Type
- Atlas
- Location
- Online
Biologics in orthopaedic surgery
https://libcat.nshealth.ca/en/permalink/provcat50416
Mazzocca, Augustus D.
--St. Louis, MO:
Elsevier
, 2019.
- Available Online
- View e-Book
- Location
- Online
- Available Online
- View e-Book
- Author
- Mazzocca, Augustus D.
- Other Authors
- Lindsay, Adam D.
- Place of Publication
- St. Louis, MO
- Publisher
- Elsevier
- Date of Publication
- 2019
- ISBN
- 9780323662079
- Subjects (MeSH)
- Orthopedic Procedures
- Biological Products - therapeutic use
- Notes
- Access to this online resource is restricted to IWK Health Centre employees working from inside the hospital network.
- Format
- e-Book
- Location
- Online
Safety of Biologics Therapy : Monoclonal Antibodies, Cytokines, Fusion Proteins, Hormones, Enzymes, Coagulation Proteins, Vaccines, Botulinum Toxins
https://libcat.nshealth.ca/en/permalink/provcat40166
Brian A. Baldo.
--Cham:
Springer
, c2016.
- Available Online
- View e-Book
- Location
- Online
This long overdue title provides a comprehensive, up-to-date, state-of-the art review of approved biologic therapies, with coverage of mechanisms of action, Indications for therapy, immunogenicity and a detailed examination of adverse effects and safety of the many and diverse therapeutic agents presented in a total of 13 chapters. It is predicted that by 2016, biologics will make up half of the world's 20 top-selling drugs and by 2018, biologic medicine sales will account for almost half of th…
- Available Online
- View e-Book
- Author
- Baldo, Brian A
- Responsibility
- Brian A. Baldo
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2016
- Physical Description
- 1 online resource (xxi, 610 p. : 106 illus., 89 illus. in color)
- ISBN
- 9783319304724
- 9783319304700 (print ed.)
- Subjects (MeSH)
- Biological Products - therapeutic use
- Biological Therapy - methods
- Drug-Related Side Effects and Adverse Reactions - prevention & control
- Abstract
- This long overdue title provides a comprehensive, up-to-date, state-of-the art review of approved biologic therapies, with coverage of mechanisms of action, Indications for therapy, immunogenicity and a detailed examination of adverse effects and safety of the many and diverse therapeutic agents presented in a total of 13 chapters. It is predicted that by 2016, biologics will make up half of the world's 20 top-selling drugs and by 2018, biologic medicine sales will account for almost half of the world's 100 biggest selling drugs. Recombinant proteins dominate the growing list of the more than 200 approved biotherapeutic agents with targeted antibodies, fusion proteins and receptors; cytokines; hormones; enzymes; proteins involved in blood-clotting, homeostasis and thrombosis; vaccines; botulinum neurotoxins; and, more recently, biosimilar preparations, comprising the majority of approved biologics. Written with clinicians, other health care professionals, and researchers in mind, Safety of Biologics Therapy examines, in a single volume, the full range of issues surrounding the safety of approved biologic therapies. A good understanding of the risks and safety issues of modern biologics therapy is increasingly being demanded of all those connected with their development, handling, prescribing, administration and subsequent patient management. In addition to being of great value to clinicians in all branches of medicine, and to nurses, pharmacists and researchers, this book will prove invaluable for students taking undergraduate and graduate courses in the above disciplines and in the biomedical sciences.
- Contents
- 1. Approved Biologics Used For Therapy and their Adverse Effects -- 2. Monoclonal Antibodies: Introduction -- 3. Monoclonal Antibodies Approved for Cancer Therapy -- 4. Other Approved Therapeutic Monoclonal Antibodies -- 5. Cytokines -- 6. Fusion Proteins -- 7. Peptide Hormones -- 8. Glycoprotein Hormones -- 9. Enzymes Approved for Therapy -- 10. Blood Coagulation -- 11. Vaccines -- 12. Botulinum Neurotoxins -- 13. Biosimilars.
- Format
- e-Book
- Location
- Online
Treatment of Inflammatory Bowel Disease with Biologics
https://libcat.nshealth.ca/en/permalink/provcat42935
edited by Adam S. Cheifetz, Joseph D. Feuerstein.
--Cham, Switzerland:
Springer
, c2018.
- Available Online
- View e-Book
- Location
- Online
This book is a concise yet comprehensive overview of the use of biologics for the treatment of Crohn's disease and ulcerative colitis. The volume details how best to utilize these medications in order to optimize their efficacy and safety, as well as how to understand, recognize, and treat complications that may arise from using biologics to treat IBD. The text also focuses on new data, novel biologics, and biosimilars of this rapidly expanding field. Written by experts in the field, Treatment …
- Available Online
- View e-Book
- Other Authors
- Cheifetz, Adam S.
- Feuerstein, Joseph D.
- Responsibility
- edited by Adam S. Cheifetz, Joseph D. Feuerstein
- Place of Publication
- Cham, Switzerland
- Publisher
- Springer
- Date of Publication
- c2018
- Physical Description
- 1 online resource (xi, 335 p.) : 22 illus., 19 illus. in color
- ISBN
- 9783319602769
- 9783319602752 (print ed.)
- 9783319602776 (print ed.)
- 9783319868233 (print ed.)
- Subjects (MeSH)
- Anti-Inflammatory Agents - therapeutic use
- Biological Products - therapeutic use
- Inflammatory Bowel Diseases - drug therapy
- Specialty
- Biological Therapy
- Gastroenterology
- Abstract
- This book is a concise yet comprehensive overview of the use of biologics for the treatment of Crohn's disease and ulcerative colitis. The volume details how best to utilize these medications in order to optimize their efficacy and safety, as well as how to understand, recognize, and treat complications that may arise from using biologics to treat IBD. The text also focuses on new data, novel biologics, and biosimilars of this rapidly expanding field. Written by experts in the field, Treatment of Inflammatory Bowel Disease with Biologics is a valuable resource for gastroenterologists, allied health professionals, fellows, and trainees who treat patients with inflammatory bowel disease.
- Contents
- Mechanism of Action and Pharmacokinetics of Biologics -- Anti-tumor Necrosis Factor Agents in Ulcerative Colitis -- Anti-tumor Necrosis Factor Agents in Crohn's Disease -- Anti-TNF Therapy for Treatment of Extraintestinal Manifestations of Inflammatory Bowel Disease -- Use of Biologics in the Postoperative Management of Crohn's Disease -- Biologics in Pregnancy and Breastfeeding -- Concomitant Use of Immunosuppressive Therapy with Tumor Necrosis Factor (TNF) Antagonists in Inflammatory Bowel Disease -- Therapeutic Drug Monitoring of Biologic Agents -- Use of Biologics in Crohn's Disease and Ulcerative Colitis Prior to Surgery and Perioperative Risks -- Cessation of Biologics—Can it be Done? -- Biologic Therapy in Pediatric Inflammatory Bowel Disease -- Infectious Complications of Biologics -- Tumor Necrosis Factor-Alpha Inhibitors and Risks of Malignancy -- Non-infectious and Non-malignant Complications of Biologics -- Biosimilars in Inflammatory Bowel Disease 2017: State of the Science, State of the Art, State of the Finances -- Anti-Integrin Agents in IBD: Efficacy and Risk of Complications -- Novel Agents in Inflammatory Bowel Disease -- Quality, Safety, and Practical Considerations of Using Biologic Therapies.
- Format
- e-Book
- Location
- Online
