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Advanced concepts in surgical research

https://libcat.nshealth.ca/en/permalink/provcat33095
edited by Mohit Bhandari, Bernd Robioneck ; associate editor, Emil Schemitsch ; managing editor, Sheila Sprague ; with contributions by Volker Alt ... [et al.]. --Stuttgart: Thieme , c2012.
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Advanced Concepts in Surgical Research is a practical, reader-friendly guide to planning, conducting, and evaluating solid, evidence-based surgical research that leads to high-quality results. Geared to the investigator who has already mastered basic principles, this book focuses on more advanced topics such as randomized controlled trials, survey design, observational studies, meta analyses, statistical concepts, reporting of data, and much more.
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Other Authors
Bhandari, Mohit
Robioneck, Bernd
Schemitsch, Emil H.
Sprague, Sheila
Alt, Volker
Responsibility
edited by Mohit Bhandari, Bernd Robioneck ; associate editor, Emil Schemitsch ; managing editor, Sheila Sprague ; with contributions by Volker Alt ... [et al.]
Place of Publication
Stuttgart
Publisher
Thieme
Date of Publication
c2012
Physical Description
1 online resource (xiv, 225 p.)
ISBN
9783131658111
9783131670212 (eISBN)
Subjects (MeSH)
Biomedical Research - methods
Clinical Trials as Topic
General Surgery
Research Design
Statistics as Topic
Specialty
General Surgery
Research
Abstract
Advanced Concepts in Surgical Research is a practical, reader-friendly guide to planning, conducting, and evaluating solid, evidence-based surgical research that leads to high-quality results. Geared to the investigator who has already mastered basic principles, this book focuses on more advanced topics such as randomized controlled trials, survey design, observational studies, meta analyses, statistical concepts, reporting of data, and much more.
Format
e-Book
Location
Online
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Basic Science Techniques in Clinical Practice

https://libcat.nshealth.ca/en/permalink/provcat30038
edited by H. R. H. Patel, M. Arya, I. S. Shergill. --London: Springer-Verlag , c2007.
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Location
Online
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Author
Patel, H.R.H
Other Authors
Arya, M
Shergill, I.S
Responsibility
edited by H. R. H. Patel, M. Arya, I. S. Shergill
Place of Publication
London
Publisher
Springer-Verlag
Date of Publication
c2007
ISBN
9781846287404
Subjects (MeSH)
Biomedical Research - methods
Clinical Laboratory Techniques
Subjects (LCSH)
Medical laboratories
Format
e-Book
Location
Online
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Biomedical Informatics for Cancer Research

https://libcat.nshealth.ca/en/permalink/provcat28720
edited by Michael F. Ochs, John T. Casagrande, Ramana V. Davuluri. --Boston, MA: Springer Science+Business Media , c2010.
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Location
Online
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Author
Ochs, Michael F
Other Authors
Casagrande, John T
Davuluri, Ramana V
Responsibility
edited by Michael F. Ochs, John T. Casagrande, Ramana V. Davuluri
Place of Publication
Boston, MA
Publisher
Springer Science+Business Media
Date of Publication
c2010
ISBN
9781441957146
Subjects (MeSH)
Biomedical Research - methods
Computational Biology - methods
Medical Informatics - methods
Medical Oncology
Subjects (LCSH)
Oncology
Medical records - Data processing
Bioinformatics
Format
e-Book
Location
Online
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Biomedical Research : An Insider's Guide

https://libcat.nshealth.ca/en/permalink/provcat39724
Seward B. Rutkove. --New York, NY: Springer , c2016.
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This comprehensive yet concise book introduces people at all levels of training--undergraduate, graduate, and medical students, residents, fellows, and junior faculty--to the basic joys and challenges of biomedical research. By discussing many key research issues, would-be and early-stage academics will not only be better informed about the world of biomedical research, but will learn a basic set of instructions to help jumpstart their careers. Biomedical Research: An Insider's Guide is divided…
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Author
Rutkove, Seward B
Responsibility
Seward B. Rutkove
Place of Publication
New York, NY
Publisher
Springer
Date of Publication
c2016
Physical Description
1 online resource (xvii, 299 p.)
ISBN
9781493936557
9781493936533 (print ed.)
Subjects (MeSH)
Biomedical Research - methods
Research Design
Abstract
This comprehensive yet concise book introduces people at all levels of training--undergraduate, graduate, and medical students, residents, fellows, and junior faculty--to the basic joys and challenges of biomedical research. By discussing many key research issues, would-be and early-stage academics will not only be better informed about the world of biomedical research, but will learn a basic set of instructions to help jumpstart their careers. Biomedical Research: An Insider's Guide is divided into five sections. The first focuses on decision points regarding whether or not to enter research and if so what type: basic, clinical, or translational. The second section focuses on the practicalities of pursuing medical research, including institutional review boards and animal care committees as well general suggestions regarding idea generation and collaboration. The third section covers a core aspect of research: writing--detailing the evolution of both grants and papers. The fourth section addresses a range of issues, including conferencing to patents to working with industry to obtaining philanthropic support. The final section deals with all-important broader life issues from job choices to being a mentor to thoughts on how to keep the big picture front and center. An invaluable resource that offers insightful, practical advice, Biomedical Research: An Insider's Guide reveals how biomedical research can be both challenging and truly rewarding.
Contents
Part 1: Basic considerations -- 1. So do you really want to pursue research? -- 2. What's in store: The brighter side of medical research -- 3. What's in store: The darker side of medical research -- 4. One degree of separation -- 5. Choosing and working with a mentor -- 6. Identifying a research niche you can call your own -- 7. Useful Definitions -- Part 2: Research Foundations and Structures -- 8. The Institutional Review Board: Do's, Don'ts, and Nevers -- 9. Animal Care and Use Committees -- 10. Research beyond humans and vertebrates -- 11. Hiring Research Staff -- 12. Strategy and Tactics: Running a Successful Laboratory -- 13. Everything you ever wanted to know about collaboration -- Part 3: Successful Paper and Grant Writing -- 14. Writing a successful research paper. I. Up to the point of submission -- 15. Writing a successful research paper. II Revising, resubmitting, and post-acceptance tasks -- 16. Funding: An overview -- 17. Where to apply for funding: making the right choices -- 18. Writing a winning grant application -- 19. Grant budgeting -- 20. Grant writing: Pearls and lumps of coal -- 21. Research Training, Fellowship, and Career grants -- 22. Grant review from the inside -- 23. Interpreting your reviews -- 24. To resubmit or not resubmit and how to do it -- Part 4: Good presentations, conferencing, networking, and other useful tools -- 25. The art of good presentation -- 26. Effective conferencing -- 27. Networking in the 21st century -- 28. Conflicts of interest -- 29. Scientific conduct and misconduct: what is right and proper, what is not, and what is somewhere in the middle -- 30. Article review and reading: being efficient and as thorough as you need to be -- 31. Patents -- 32. Working with industry -- Part 5: Career choices and life lessons -- 33. Jobs in biomedical science: seeking, landing, and changing -- 34. Academic Promotion and Titles -- 35. On being a mentor -- 36. Yardsticks of success -- 37. Research Life Lesson #1: Everything takes longer than you think, so plan for it -- 38. Research life lesson #2: A person's research is endlessly important to them -- 39. Research Life lesson #3: Balance, timing, cycles and seeing the big picture -- 40. Research Life Lesson #4: Your career is an ultramarathon, not a sprint -- 41. Conclusion: Nothing satisfies like meaningful work.
Format
e-Book
Location
Online
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Clinical Research Informatics

https://libcat.nshealth.ca/en/permalink/provcat31039
Rachel L. Richesson, James E. Andrews, editors. --London: Springer , c2012.
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Clinical research informatics (CRI) is the application of informatics principles and techniques to support the spectrum of activities and business processes that instantiate clinical research. Informatics, defined generally as the intersection of information and computer science with a health-related discipline, has a foundation drawn from many well-established, theory-based disciplines, including computer science, library and information science, cognitive science, psychology, and sociology. T…
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Other Authors
Richesson, Rachel L
Andrews, James E
Responsibility
Rachel L. Richesson, James E. Andrews, editors
Place of Publication
London
Publisher
Springer
Date of Publication
c2012
Physical Description
1 online resource (ix, 419 p. : 29 ill., 15 ill. in color)
Series Title
Health informatics
ISBN
9781848824485
Subjects (MeSH)
Biomedical Research - methods
Informatics
Subjects (LCSH)
Medical laboratories
Medical records - Data processing
Abstract
Clinical research informatics (CRI) is the application of informatics principles and techniques to support the spectrum of activities and business processes that instantiate clinical research. Informatics, defined generally as the intersection of information and computer science with a health-related discipline, has a foundation drawn from many well-established, theory-based disciplines, including computer science, library and information science, cognitive science, psychology, and sociology. The newly articulated yet fundamental theorem of informatics states that information technology should be used to enable humans to function and perform better together than humans alone, and so informatics is a source for supportive technologies and tools that enhance--but not replace--unreservedly human processes. Clinical Research Informatics contributes to the ongoing dialogues among researchers and practitioners in CRI as they continue to rise to the challenges of a dynamic and evolving clinical research environment. The development of CRI as a sub-discipline of informatics, and as an independent/maturing professional practice area in its own right, drives a growing pool of scientific literature based on original CRI research, and high-impact tools and systems will be developed. CRI leaders and stakeholder groups will continue to support and create communities of discourse that will address much needed practice standards in CRI, improved safety and efficiencies in clinical research, data standards in clinical research, policy issues, educational standards and instructional resources. The Editors and contributors to this book are among the most active and engaged in the CRI domain and provide an excellent primer for deeper explorations into this emerging discipline. Certain themes are highlighted, including the changing role of the consumer, movement toward transparency, growing needs for global coordination and cooperation on many levels, and the merging together of clinical care delivery and research as part of a changing paradigm in global healthcare delivery--all in the context of rapid innovations in technology and explosions of data sources, types, and volume. This book is therefore of considerable interest to all students of biomedical informatics, from the newcomer to the professional informatician.
Contents
Section I: Contexts of Clinical Research Informatics -- Introduction to Clinical Research Informatics -- From Notations to Data: The Digital Transformation of Clinical Research -- Clinical Research Environment. - Statistical and Study Design Foundations of Clinical Research -- Informatics Approaches to Participant Recruitment -- The Evolving Role of Consumers -- Clinical Research in the Post-Genomic Era -- Section II: Data Management and Systems in Clinical Research -- Clinical Research Information Systems -- Study Protocol Representation -- Data Quality in Clinical Research -- Patient-Reported Outcome Data -- Biobanking Challenges and Informatics Opportunities -- Patient Registries -- Section III: Knowledge Representation and Discovery -- Knowledge Representation and Ontologies -- Non-hypothesis Driven Research: Data Mining and Knowledge Discovery -- Natural Language Processing, Electronic Health Records, and Clinical Research -- Section IV: The Future of Clinical Research, Health, and Clinical Research Informatics -- Data Sharing: Electronic Health Records and Research Interoperability -- Standards Development and the Future of Research Data Sources, Interoperability, and Exchange -- Pharmacovigilance -- Clinical Trials Registries and Results Databases -- Future Directions in Clinical Research Informatics -- Index.
Format
e-Book
Location
Online
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Clinical research methodology and evidence-based medicine : the basics

https://libcat.nshealth.ca/en/permalink/provcat24288
Babu, Ajit N. --Tunbridge Wells, England: Anshan , 2008.
Call Number
W 20.5 B115c 2008
Location
Dickson Building
Call Number
W 20.5 B115c 2008
Author
Babu, Ajit N
Place of Publication
Tunbridge Wells, England
Publisher
Anshan
Date of Publication
2008
Physical Description
182 p.
ISBN
9781905740901
Subjects (MeSH)
Biomedical Research - methods
Research Design
Evidence-Based Medicine
Format
Book
Location
Dickson Building
Copies
1
Loan Period
3 weeks
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Clinical Research Methods for Surgeons

https://libcat.nshealth.ca/en/permalink/provcat28637
edited by David F. Penson, John T. Wei. --Totowa, NJ: Humana Press , c2007.
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Location
Online
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Author
Penson, David F
Other Authors
Wei, John T
Responsibility
edited by David F. Penson, John T. Wei
Place of Publication
Totowa, NJ
Publisher
Humana Press
Date of Publication
c2007
ISBN
9781597452304
Subjects (MeSH)
Biomedical Research - methods
General Surgery - methods
Research Design
Subjects (LCSH)
Surgery
Biomedical research
Format
e-Book
Location
Online
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Data and Text Processing for Health and Life Sciences

https://libcat.nshealth.ca/en/permalink/provcat43941
Francisco M. Couto. --Cham: SpringerOpen , c2019.
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Access
Open access
Location
Online
This open access book is a step-by-step introduction on how shell scripting can help solve many of the data processing tasks that Health and Life specialists face everyday with minimal software dependencies. The examples presented in the book show how simple command line tools can be used and combined to retrieve data and text from web resources, to filter and mine literature, and to explore the semantics encoded in biomedical ontologies. To store data this book relies on open standard text fil…
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Author
Couto, Francisco M.
Responsibility
Francisco M. Couto
Place of Publication
Cham
Publisher
SpringerOpen
Date of Publication
c2019
Physical Description
1 online resource (xv, 98 p.) : 483 illus., 74 illus. in color.
Series Vol.
v. 1137
Series Title
Advances in experimental medicine and biology
ISBN
9783030138455
9783030138448 (Print ed.)
9783030138462 (Print ed.)
ISSN
0065-2598
Subjects (MeSH)
Biomedical Research - methods
Data Mining
Electronic Data Processing
Medical Informatics - methods
Specialty
Medical Informatics
Abstract
This open access book is a step-by-step introduction on how shell scripting can help solve many of the data processing tasks that Health and Life specialists face everyday with minimal software dependencies. The examples presented in the book show how simple command line tools can be used and combined to retrieve data and text from web resources, to filter and mine literature, and to explore the semantics encoded in biomedical ontologies. To store data this book relies on open standard text file formats, such as TSV, CSV, XML, and OWL, that can be open by any text editor or spreadsheet application. The first two chapters, Introduction and Resources, provide a brief introduction to the shell scripting and describe popular data resources in Health and Life Sciences. The third chapter, Data Retrieval, starts by introducing a common data processing task that involves multiple data resources. Then, this chapter explains how to automate each step of that task by introducing the required commands line tools one by one. The fourth chapter, Text Processing, shows how to filter and analyze text by using simple string matching techniques and regular expressions. The last chapter, Semantic Processing, shows how XPath queries and shell scripting is able to process complex data, such as the graphs used to specify ontologies. Besides being almost immutable for more than four decades and being available in most of our personal computers, shell scripting is relatively easy to learn by Health and Life specialists as a sequence of independent commands. Comprehending them is like conducting a new laboratory protocol by testing and understanding its procedural steps and variables, and combining their intermediate results. Thus, this book is particularly relevant to Health and Life specialists or students that want to easily learn how to process data and text, and which in return may facilitate and inspire them to acquire deeper bioinformatics skills in the future.
Contents
Introduction -- Resources -- Data Retrieval -- Text Processing -- Semantic Processing.
Access
Open access
Format
e-Book
Location
Online
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Essentials of clinical research

https://libcat.nshealth.ca/en/permalink/provcat33263
Stephen P. Glasser, editor. (Second edition) --Cham, Switzerland: Springer , c2014.
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In its extensively revised and updated Second Edition, this book provides a solid foundation for readers interested in clinical research. Discussion encompasses genetic, pharmacoepidemiologic and implementation research. All chapters have been updated with new information and many new tables have been added to elucidate key points. The book now offers discussion on how to handle missing data when analyzing results, and coverage of Adaptive Designs and Effectiveness Designs and new sections on C…
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Other Authors
Glasser, Stephen P
Responsibility
Stephen P. Glasser, editor
Edition
Second edition
Place of Publication
Cham, Switzerland
Publisher
Springer
Date of Publication
c2014
Physical Description
1 online resource (vi, 461 pages)
ISBN
9783319054704 (electronic bk.)
9783319054698
Subjects (MeSH)
Biomedical Research - methods
Clinical Trials as Topic - methods
Statistics as Topic - methods
Abstract
In its extensively revised and updated Second Edition, this book provides a solid foundation for readers interested in clinical research. Discussion encompasses genetic, pharmacoepidemiologic and implementation research. All chapters have been updated with new information and many new tables have been added to elucidate key points. The book now offers discussion on how to handle missing data when analyzing results, and coverage of Adaptive Designs and Effectiveness Designs and new sections on Comparative Effectiveness Research and Pragmatic Trials. Chapter 6 includes new material on Phase 0 Trials, expanded coverage of Futility Trials, a discussion of Medical Device approval, Off Label Drug use and the role of the FDA in regulating advertising. Additional new information includes the role of pill color and shape in association with the placebo effect and an examination of issues surrounding minority recruitment. The final chapter offers a new section on manuscript preparation along with a discussion of various guidelines being adopted by journals: CONSORT, STROBE, PRISMA, MOOSE and others; and coverage of Conflicts of Interest, Authorship, Coercive Citation, and Disclosures in Industry-Related Associations. Building on the strengths of its predecessor in its comprehensive approach and authoritative advice, the new edition offers more of what has made this book a popular, trusted resource for students and working researchers alike.
Contents
The Beginning - Historical Aspects of Clinical Research, Clinical Research: Definitions, "Anatomy and Physiology," and the Quest for "Universal Truth" -- Introduction to Clinical Research Concepts, Essential Characteristics of Clinical Research, Overview of Clinical Research Study Designs -- A Focus on Clinical Trials -- Alternative Interventional Study Designs -- Phase 4 (Postmarketing) Research -- The Role of the USA Food and Drug Administration in Clinical Research -- The Placebo and Nocebo Effect -- Recruitment and Retention in Clinical Research -- Data Safety and Monitoring Boards (DSMBs) -- Meta-analysis, Evidence-Based Medicine, and Clinical Guidelines -- Research Methods for Genetic Studies -- Research Methods for Pharmacoepidemiology Studies -- Implementation Research: Beyond the Traditional Randomized Controlled Trial -- Research Methodology for Studies of Diagnostic Tests -- Statistical Power and Sample Size: Some Fundamentals for Clinician Researchers -- Association, Cause, and Correlation -- Bias, Confounding, and Effect Modification (Interaction) -- It's All About Uncertainty -- Grant and Manuscript Writing -- The Media and Clinical Research -- Mentoring and Advising -- Presentation Skills: How to Present Research Results.
Format
e-Book
Location
Online
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Foundations of clinical research : applications to practice

https://libcat.nshealth.ca/en/permalink/provcat53407
Portney, Leslie G. (3rd ed.) --Upper Saddle River, NJ: Pearson , 2009.
Call Number
W 20.5 P853 2009
Location
IWK Health Sciences Library
Call Number
W 20.5 P853 2009
Author
Portney, Leslie G.
Other Authors
Watkins, Mary P.
Edition
3rd ed.
Place of Publication
Upper Saddle River, NJ
Publisher
Pearson
Date of Publication
2009
Physical Description
892 p.
ISBN
9.78E+11
Subjects (MeSH)
Biomedical Research - methods
Statistics - methods
Statistics as Topic - methods
Research Design
Format
Book
Location
IWK Health Sciences Library
Copies
1
Loan Period
2 weeks
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Key Topics in Surgical Research and Methodology

https://libcat.nshealth.ca/en/permalink/provcat28939
edited by Thanos Athanasiou, Haile Debas, Ara Darzi. --Berlin, Heidelberg: Springer , c2010.
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Location
Online
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Author
Athanasiou, Thanos
Other Authors
Debas, Haile
Darzi, Ara
Responsibility
edited by Thanos Athanasiou, Haile Debas, Ara Darzi
Place of Publication
Berlin, Heidelberg
Publisher
Springer
Date of Publication
c2010
ISBN
9783540719151
Subjects (MeSH)
General Surgery - methods
Biomedical Research - methods
Subjects (LCSH)
Surgery
Biomedical research
Format
e-Book
Location
Online
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Medical Imaging and Radiotherapy Research : Skills and Strategies

https://libcat.nshealth.ca/en/permalink/provcat45377
Aarthi Ramlaul, editor. (Second edition) --Cham: Springer , c2020.
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Location
Online
This exciting new book equips radiography students and practitioners with the key skills and strategies required to undertake research within medical imaging and radiotherapy and to disseminate the research findings effectively. Quantitative and qualitative research methods are covered, with guidance provided on the entire research process, from literature researching, information management and literature evaluation through to data collection, data analysis, and writing up. Attention is drawn …
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Other Authors
Ramlaul, Aarthi
Responsibility
Aarthi Ramlaul, editor
Edition
Second edition
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2020
Physical Description
1 online resource (xix, 427 p.) : 71 illus., 36 illus. in color
ISBN
9783030379445
9783030379438 (Print ed.)
9783030379452 (Print ed.)
9783030379469 (Print ed.)
Subjects (MeSH)
Biomedical Research - methods
Diagnostic Imaging
Radiotherapy
Specialty
Diagnostic Imaging
Radiotherapy
Research
Abstract
This exciting new book equips radiography students and practitioners with the key skills and strategies required to undertake research within medical imaging and radiotherapy and to disseminate the research findings effectively. Quantitative and qualitative research methods are covered, with guidance provided on the entire research process, from literature researching, information management and literature evaluation through to data collection, data analysis, and writing up. Attention is drawn to sampling errors and other potential sources of bias, and the conduct of randomized controlled trials, systematic reviews, and meta-analyses are clearly explained. Specific instruction is given on the structure and presentation of dissertations, writing journal articles for publication, and the dissemination of research findings at conferences. Information on patient and public involvement in research and research funding bodies are also provided with advice on how to maximize the likelihood of success when submitting applications for funding.
Contents
Part I. Getting started with research -- 1. History of research -- 2. Finding a research question -- 3. Literature searching -- 4. Literature evaluation and critique -- 5. Reflective practice and the patient voice -- 6. Ethical considerations -- Part II. Research planning -- 7. Planning your research study -- 8. Types of information -- 9. Epidemiological research methods -- 10. Sampling errors, bias and objectivity -- 11. Research outcome measures -- Part III. Health technology assessment -- 12. Health technology assessment -- Part IV. Dosimetry and service evaluation -- 13. Dosimetry -- 14. Clinical audit -- Part V. Data analysis -- 15. Quantitative methods and analysis -- 16. Qualitative methods and analysis -- Part VI. Writing up and disseminating -- 17. Dissertation structure and presentation -- 18. Writing for publication and presenting at conferences -- 19. Applying for research funding -- 20. Research writing: tips and common errors.
Format
e-Book
Location
Online
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Medical Statistics : For Beginners

https://libcat.nshealth.ca/en/permalink/provcat41951
Ramakrishna HK. --Singapore: Springer , 2017.
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This book deals with statistics in medicine in a simple way. The text is supported by abundant examples from medical data. This book aims to explain and simplify the process of data presentation. Further aspects addressed include how to design and conduct clinical trials, and how to write journal articles.
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Author
Ramakrishna, H.K.
Responsibility
Ramakrishna HK
Place of Publication
Singapore
Publisher
Springer
Date of Publication
2017
Physical Description
1 online resource (xv, 181 pages) : 110 illus. in color
ISBN
9789811019234
9789811019227 (print ed.)
Subjects (MeSH)
Biomedical Research - methods
Statistics as Topic
Abstract
This book deals with statistics in medicine in a simple way. The text is supported by abundant examples from medical data. This book aims to explain and simplify the process of data presentation. Further aspects addressed include how to design and conduct clinical trials, and how to write journal articles.
Contents
1. Introduction -- 2. My Journey from a Rural Surgeon to an Author -- 3. Understanding Biostatistics, Probability, and Tests of Significance -- 4. Understanding Basic Statistical Terms -- 5. Tests of Significance -- 6. Other Commonly Used Concepts -- 7. Designing a Study/Clinical Trial/Dissertation, Etc. -- 8. Writing an Article for Journals -- 9. Evidence-Based Medicine -- 10. Model Example.
Format
e-Book
Location
Online
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Modern Bayesian Statistics in Clinical Research

https://libcat.nshealth.ca/en/permalink/provcat42615
Ton J. Cleophas, Aeilko H. Zwinderman. --Cham: Springer , c2018.
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Online
The current textbook has been written as a help to medical/health professionals and students for the study of modern Bayesian statistics, where posterior and prior odds have been replaced with posterior and prior likelihood distributions. Why may likelihood distributions better than normal distributions estimate uncertainties of statistical test results? Nobody knows for sure, and the use of likelihood distributions instead of normal distributions for the purpose has only just begun, but alread…
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Author
Cleophas, Ton J.
Other Authors
Zwinderman, Aeilko H.
Responsibility
Ton J. Cleophas, Aeilko H. Zwinderman
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2018
Physical Description
1 online resource (x, 188 p.) : 84 illus., 38 illus. in color
ISBN
9783319927473
9783319927466 (print ed.)
9783319927480 (print ed.)
Subjects (MeSH)
Bayes Theorem
Biomedical Research - methods
Data Interpretation, Statistical - methods
Statistics as Topic
Specialty
Data Science
Research
Abstract
The current textbook has been written as a help to medical/health professionals and students for the study of modern Bayesian statistics, where posterior and prior odds have been replaced with posterior and prior likelihood distributions. Why may likelihood distributions better than normal distributions estimate uncertainties of statistical test results? Nobody knows for sure, and the use of likelihood distributions instead of normal distributions for the purpose has only just begun, but already everybody is trying and using them. SPSS statistical software version 25 (2017) has started to provide a combined module entitled Bayesian Statistics including almost all of the modern Bayesian tests (Bayesian t-tests, analysis of variance (anova), linear regression, crosstabs etc.). Modern Bayesian statistics is based on biological likelihoods, and may better fit clinical data than traditional tests based normal distributions do. This is the first edition to systematically imply modern Bayesian statistics in traditional clinical data analysis. This edition also demonstrates that Markov Chain Monte Carlo procedures laid out as Bayesian tests provide more robust correlation coefficients than traditional tests do. It also shows that traditional path statistics are both textually and conceptionally like Bayes theorems, and that structural equations models computed from them are the basis of multistep regressions, as used with causal Bayesian networks. .
Contents
General Introduction to Modern Bayesian Statistics -- Traditional Bayes: Diagnostic Tests, Genetic Research, Bayes and Drug Trials -- Bayesian Tests for One Sample Continuous Data -- Bayesian Tests for One Sample Binary Data -- Bayesian Paired T-Tests -- Bayesian Unpaired T-Tests -- Bayesian Regressions -- Bayesian Analysis of Variance (Anova) -- Bayesian Loglinear Regression -- Bayesian Poisson Rate Analysis -- Bayesian Pearson Correlations -- Bayesian Statistics: Markov Chain Monte Carlo Sampling -- Bayes and Causal Relationships -- Bayesian Network.
Format
e-Book
Location
Online
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Principles and practice of clinical research

https://libcat.nshealth.ca/en/permalink/provcat24688
Gallin, John I. (2nd ed.) --Amsterdam, Netherlands: Academic Press , 2007.
Call Number
W 20.5 P957 2007
Location
Dickson Building
Halifax Infirmary
Call Number
W 20.5 P957 2007
Author
Gallin, John I
Other Authors
Ognibene, Frederick P
Edition
2nd ed.
Place of Publication
Amsterdam, Netherlands
Publisher
Academic Press
Date of Publication
2007
Physical Description
430 p.
ISBN
9780123694409
Subjects (MeSH)
Biomedical Research - methods
Format
Book
Location
Dickson Building
Halifax Infirmary
Copies
2
Loan Period
3 weeks
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Principles and practice of clinical research

https://libcat.nshealth.ca/en/permalink/provcat27610
Gallin, John I. (2nd ed.) --Amsterdam, Netherlands: Elsevier Academic Press , 2007.
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Location
Online
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Author
Gallin, John I
Other Authors
Ognibene, Frederick P
Edition
2nd ed.
Place of Publication
Amsterdam, Netherlands
Publisher
Elsevier Academic Press
Date of Publication
2007
Physical Description
430 p.
ISBN
9780080489568
Subjects (MeSH)
Biomedical Research - methods
Format
e-Book
Location
Online
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Principles of Research Methodology : A Guide for Clinical Investigators

https://libcat.nshealth.ca/en/permalink/provcat30973
Phyllis G. Supino, Jeffrey S. Borer, editors. --New York, NY: Springer , c2012.
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Online
Principles of Research Methodology: A Guide for Clinical Investigators is the definitive, comprehensive guide to understanding and performing clinical research. Designed for medical students, physicians, basic scientists involved in translational research, and other health professionals, this indispensable reference also addresses the unique challenges and demands of clinical research and offers clear guidance in becoming a more successful member of a medical research team and critical reader o…
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Other Authors
Supino, Phyllis G.
Borer, Jeffrey S.
Responsibility
Phyllis G. Supino, Jeffrey S. Borer, editors
Place of Publication
New York, NY
Publisher
Springer
Date of Publication
c2012
Physical Description
1 online resource (xvi, 276 p. : 55 ill.)
ISBN
9781461433606
Subjects (MeSH)
Biomedical Research - methods
Clinical Trials as Topic
Research Design
Subjects (LCSH)
Practice of medicine
Research
Abstract
Principles of Research Methodology: A Guide for Clinical Investigators is the definitive, comprehensive guide to understanding and performing clinical research. Designed for medical students, physicians, basic scientists involved in translational research, and other health professionals, this indispensable reference also addresses the unique challenges and demands of clinical research and offers clear guidance in becoming a more successful member of a medical research team and critical reader of the medical research literature. The book covers the entire research process, beginning with the conception of the research problem to publication of findings. Principles of Research Methodology: A Guide for Clinical Investigators comprehensively and concisely presents concepts in a manner that is relevant and engaging to read. The text combines theory and practical application to familiarize the reader with the logic of research design and hypothesis construction, the importance of research planning, the ethical basis of human subjects research, the basics of writing a clinical research protocol and scientific paper, the logic and techniques of data generation and management, and the fundamentals and implications of various sampling techniques and alternative statistical methodologies. Organized in thirteen easy to read chapters, the text emphasizes the importance of clearly-defined research questions and well-constructed hypothesis (reinforced throughout the various chapters) for informing methods and in guiding data interpretation. Written by prominent medical scientists and methodologists who have extensive personal experience in biomedical investigation and in teaching key aspects of research methodology to medical students, physicians and other health professionals, the authors expertly integrate theory with examples and employ language that is clear and useful for a general medical audience. A major contribution to the methodology literature, Principles of Research Methodology: A Guide for Clinical Investigators is an authoritative resource for all individuals who perform research, plan to perform it, or wish to understand it better.
Contents
Overview of the Research Process -- Developing a Research Problem -- The Research Hypothesis: Role and Construction -- Design and Interpretation of Observational Studies: Cohort, Case-Control and Cross-Sectional Designs -- Fundamental Issues in Evaluating the Impact of Interventions: Sources and Control of Bias -- Protocol Development and Preparation for a Clinical Trial -- Data Collection and Management in Clinical Research -- Constructing and Evaluating Self Report Measures -- Selecting and Evaluating Secondary Data: The Role of Systematic Reviews and Meta-Analysis -- Sampling Methodology: Implications for Drawing Conclusions from Clinical Research Findings -- Introductory Statistics in Medical Research -- Ethical Issues in Clinical Research -- How to Prepare a Scientific Paper.
Format
e-Book
Location
Online
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Research handbook for health care professionals

https://libcat.nshealth.ca/en/permalink/provcat24551
Hickson, Mary. --Chichester, England: Blackwell Pub. , 2008.
Call Number
W 20.5 H631r 2008
Location
Halifax Infirmary
Call Number
W 20.5 H631r 2008
Author
Hickson, Mary
Place of Publication
Chichester, England
Publisher
Blackwell Pub.
Date of Publication
2008
Physical Description
184 p.
ISBN
9781405177375
Subjects (MeSH)
Biomedical Research - methods
Health Services Research - methods
Research Design
Writing
Format
Book
Location
Halifax Infirmary
Loan Period
3 weeks
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The SAGE handbook of qualitative methods in health research

https://libcat.nshealth.ca/en/permalink/provcat25139
edited by Ivy Bourgeault, Robert Dingwall, and Raymond De Vries. --Los Angeles, CA: Sage Publications , 2010.
Call Number
W 20.5 S129 2010
Location
Dickson Building
Call Number
W 20.5 S129 2010
Other Authors
Bourgeault, Ivy
Dingwall, Robert
De Vries, Raymond
Responsibility
edited by Ivy Bourgeault, Robert Dingwall, and Raymond De Vries
Place of Publication
Los Angeles, CA
Publisher
Sage Publications
Date of Publication
2010
Physical Description
xxv, 760 p.
ISBN
9781847872920
1847872921
Subjects (MeSH)
Qualitative Research
Research Design
Biomedical Research - methods
Format
Book
Location
Dickson Building
Loan Period
3 weeks
Less detail

Single Subject Designs in Biomedicine

https://libcat.nshealth.ca/en/permalink/provcat29103
by Janine E. Janosky, Shelley L. Leininger, Michael P. Hoerger, Terry M. Libkuman. --Dordrecht ; New York: Springer Netherlands , c2009.
Available Online
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Location
Online
Available Online
View e-Book
Author
Janosky, Janine E
Other Authors
Leininger, Shelley L
Hoerger, Michael P
Libkuman, Terry M
Responsibility
by Janine E. Janosky, Shelley L. Leininger, Michael P. Hoerger, Terry M. Libkuman
Place of Publication
Dordrecht ; New York
Publisher
Springer Netherlands
Date of Publication
c2009
ISBN
9789048124442
Subjects (MeSH)
Biomedical Research - methods
Research Design
Subjects (LCSH)
Biomedical research
Format
e-Book
Location
Online
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