The heart and circulation : an integrative model
https://libcat.nshealth.ca/en/permalink/provcat33285
Branko Furst.
--London:
Springer
, c2014.
- Available Online
- View e-Book
- Location
- Online
What drives the circulation? In this comprehensive review of existing circulation models, the conventional view that the heart is a pressure-propulsion pump is challenged. The existing models fail to explain an increasing number of observed circulatory phenomena. A unifying circulation model is proposed in which the blood, responding to metabolic demands of the tissues, is the primary regulator of cardiac output. This new model arises from accumulated clinical and experimental evidence. The hea…
- Available Online
- View e-Book
- Author
- Furst, Branko
- Responsibility
- Branko Furst
- Place of Publication
- London
- Publisher
- Springer
- Date of Publication
- c2014
- Physical Description
- 1 online resource (xxix, 226 pages)
- ISBN
- 9781447152774 (electronic bk.)
- 9781447152767
- Subjects (MeSH)
- Blood Circulation - physiology
- Cardiovascular System - embryology
- Heart - physiology
- Hemodynamics - physiology
- Myocardium
- Subjects (LCSH)
- Hemodynamics
- Blood Circulation
- Blood - Circulation
- Cardiology
- Abstract
- What drives the circulation? In this comprehensive review of existing circulation models, the conventional view that the heart is a pressure-propulsion pump is challenged. The existing models fail to explain an increasing number of observed circulatory phenomena. A unifying circulation model is proposed in which the blood, responding to metabolic demands of the tissues, is the primary regulator of cardiac output. This new model arises from accumulated clinical and experimental evidence. The heart, rather than being an organ of blood propulsion, assumes a secondary role and generates pressure by impeding the flow of blood. This is supported by examples from the fields of early embryonic circulation, comparative phylogeny, functional morphology, exercise physiology and a range of clinical scenarios. The Heart and Circulation: An Integrative Model offers a paradigm shift in the understanding of circulatory phenomena. It will become a valuable resource for all those clinicians, researchers, educators and students who, having been confronted with the paradox of the circulation, are looking for a broader interpretation.
- Contents
- Part I. Embryonic Circulation -- Early Embryo Circulation -- The Onset of Circulation -- Hemodynamics of the Early Embryo Circulation -- Flow Patterns in the Early Embryo Circulation -- Is There a Circulation Without a Heart? -- Embryo Heart is not a Peristaltic Pump -- Flow Perturbation Experiments -- Heart Rate Perturbations -- The Heart as Generator of Pressure -- Ventriculo-Vascular Interaction -- A Brief Comparative Phylogeny -- Evolutionary Aspect of the Rhythmical System -- Part II. Mature Circulation -- Functional Morphology of the Heart -- Regulation of Cardiac Output -- Circulatory and Respiratory Functions of the Blood -- Models of the Heart -- Cardiovascular Response during Exercise -- Hemodynamic Effects of Aortic Occlusion -- Increased Pulmonary Flows -- Single Ventricle Physiology -- Blood as an Organ.
- Format
- e-Book
- Location
- Online
The Heart and Circulation : An Integrative Model
https://libcat.nshealth.ca/en/permalink/provcat45053
Branko Furst.
(Second edition)
--Cham:
Springer
, c2020.
- Available Online
- View e-Book
- Location
- Online
This extensively revised second edition traces the development of the basic concepts in cardiovascular physiology in light of the accumulated experimental and clinical evidence. It considers the early embryonic circulation, where blood circulation suggests the existence of a motive force, tightly coupled to the metabolic demands of the tissues. It proposes that rather than being an organ of propulsion, the heart, serves as an organ of control, generating pressure by rhythmically impeding blood …
- Available Online
- View e-Book
- Author
- Furst, Branko
- Responsibility
- Branko Furst
- Edition
- Second edition
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2020
- Physical Description
- 1 online resource (xl, 376 p.) : 136 illus., 105 illus. in color
- ISBN
- 9783030250621
- 9783030250614 (Print ed.)
- 9783030250638 (Print ed.)
- 9783030250645 (Print ed.)
- Subjects (MeSH)
- Blood Circulation - physiology
- Cardiovascular System - embryology
- Heart - physiology
- Hemodynamics - physiology
- Myocardium
- Specialty
- Cardiology
- Abstract
- This extensively revised second edition traces the development of the basic concepts in cardiovascular physiology in light of the accumulated experimental and clinical evidence. It considers the early embryonic circulation, where blood circulation suggests the existence of a motive force, tightly coupled to the metabolic demands of the tissues. It proposes that rather than being an organ of propulsion, the heart, serves as an organ of control, generating pressure by rhythmically impeding blood flow. New and expanded chapters cover the arterial pulse, circulation in the upright posture, microcirculation and functional heart morphology. Heart and Circulation offers a new perspective for deeper understanding of the human cardiovascular system. It is therefore a thought-provoking resource for cardiologists, cardiac surgeons and trainees interested in models of human circulation.
- Contents
- Part I. Embryonic Circulation -- 1. Early Embryo Circulation -- 2. The Onset of Circulation -- 3. Hemodynamics of the Early Embryo Circulation -- 4. Flow Patterns in the Early Embryo Circulation -- 5. Is There a Circulation Without a Heart? -- 6. The Embryo Heart is Not a Peristaltic Pump -- 7. Flow Perturbation Experiments -- 8. Heart Rate Perturbations -- 9. The Heart as a Generator of Pressure -- 10. Ventriculo–Vascular Interaction -- 11. A Brief Comparative Phylogeny -- 12. Evolutionary Aspect of the Rhythmical System -- Part II. Mature Circulation -- 13. Functional Morphology of the Heart -- 14. Regulation of Cardiac Output -- 15. Circulatory and Respiratory Functions of the Blood -- 16. Models of the Heart -- 17. Cardiovascular Response During Exercise -- 18. Hemodynamic Effects of Aortic Occlusion -- 19. Increased Pulmonary Flows -- 20. Single Ventricle Physiology -- 21. Microcirculation -- Part III. Human Circulation -- 22. Arterial Pulse -- 23. Heartbeat and Respiration: Toward a Functional Chronobiology -- 24. The Effect of Gravity and Upright Posture on Circulation -- 25. The Integrative Model of Circulation: A Synthesis.
- Format
- e-Book
- Location
- Online
Vortex Formation in the Cardiovascular System
https://libcat.nshealth.ca/en/permalink/provcat30879
Arash Kheradvar, Gianni Pedrizzetti.
--London:
Springer
, c2012.
- Available Online
- View e-Book
- Location
- Online
Vortex formation has received much attention over the past few years. Vortices occur in nature wherever propulsive flow exists; from erupting volcanoes to the ones generated by squid and jellyfish to propel them. There has been particular interest in the wide variety of vortices that develop in the cardiovascular system, particularly in the cardiac chambers and in large arteries. These vortices play fundamental roles in the normal physiology and provide proper balance between blood motion and s…
- Available Online
- View e-Book
- Author
- Kheradvar, Arash
- Other Authors
- Pedrizzetti, Gianni
- Responsibility
- Arash Kheradvar, Gianni Pedrizzetti
- Place of Publication
- London
- Publisher
- Springer
- Date of Publication
- c2012
- Physical Description
- 1 online resource (xiii, 164 p. : 75 ill., 42 ill. in color)
- ISBN
- 9781447122883
- Subjects (MeSH)
- Blood Circulation - physiology
- Hemodynamics - physiology
- Subjects (LCSH)
- Cardiology
- Abstract
- Vortex formation has received much attention over the past few years. Vortices occur in nature wherever propulsive flow exists; from erupting volcanoes to the ones generated by squid and jellyfish to propel them. There has been particular interest in the wide variety of vortices that develop in the cardiovascular system, particularly in the cardiac chambers and in large arteries. These vortices play fundamental roles in the normal physiology and provide proper balance between blood motion and stresses on the surrounding tissues. In contrast, formation of unnatural vortices may alter the momentum transfer in the blood flow and increase energy dissipation. Vortex Formation in the Cardiovascular System reviews the current knowledge of vortex formation, from the basic physics to cardiac physiology. There is a particular focus on the formation of vortices at different locations inside the heart, the effect of cardiac devices and surgery on vortex formation, fluid dynamics of the artificial heart valves and ventricular assist devices. The Authors have translated physical, mathematical and engineering concepts related to vortex formation into a clinical perspective with the objective to advance cardiovascular patient care. This book therefore represents a comprehensive and valuable resource for those involved in the field of cardiology and cardiovascular physiology, cardiovascular surgeons, interventional cardiologists, medical bioengineers and researchers in fluid mechanics.
- Contents
- [Machine generated contents note] 1. Fundamental Fluid Mechanics -- 1.1. Fluids and Solids, Blood and Tissues -- 1.2. Conservation of Mass -- 1.3. Conservation of Momentum and Bernoulli Theorem -- 1.4. Conservation of Momentum and Viscosity -- 1.5. Boundary Layer and Wall Shear Stress -- 1.6. Simple Flows and Concepts of Cardiovascular Interest -- References -- 2. Vortex Dynamics -- 2.1. Definitions -- 2.2. Dynamics of Vorticity -- 2.3. Boundary Layer Separation -- 2.4. Vortex Formation -- 2.5. Three-Dimensional Vortex Formation -- 2.6. Energy Loss and Force of Vortex Formation -- 2.7. Vortex Interactions -- 2.8. Mention to Turbulence -- References -- 3. Vortex Formation in the Heart -- 3.1. Mitral Valve and Transmitral Flow -- 3.1.1. Mitral Valve Functional Anatomy -- 3.1.2. Transmitral Flow -- 3.1.3. Transmitral Vortex Formation -- 3.1.4. Transmitral Vortex Formation Time Index: A Parameter to Couple Diastole and Systole -- 3.1.5. Mitral Annulus Recoil -- 3.1.6. Grading Diastolic Dysfunction -- 3.1.7. Outcome Planning for Diastolic Dysfunction -- 3.2. Aortic Valve and Sinuses of Valsalva -- 3.2.1. Functional Anatomy -- 3.2.2. Vortex Formation in Aortic Sinus -- 3.3. Vortex Formation in the Right Heart -- 3.4. Vortex Formation in the Embryonic Heart -- 3.5. Linking Cardiac Muscle Function to Vortex Formation -- 3.5.1. Preejection -- 3.5.2. Ejection -- 3.5.3. Isovolumic Relaxation -- 3.5.4. Early and Late Diastole -- 3.6. Effect of Left Ventricular Diseases on Vortex Formation -- 3.6.1. Vortex Formation in LV Systolic Dysfunction -- 3.6.2. Vortex Formation in LV Regional Myocardial Dysfunction -- 3.6.3. Hypertrophic Left Ventricle and Diastolic Dysfunction -- 3.6.4. Vortex Formation in Mitral Stenosis -- 3.6.5. Vortex Formation Time Index and Percutaneous Balloon Mitral Valvotomy -- References -- 4. Effect of Cardiac Devices and Surgery on Vortex Formation -- 4.1. Vortex Formation in Presence of Bioprosthetic Heart Valves -- 4.1.1. Mitral Bioprosthetic Valves -- 4.1.2. Aortic Bioprosthetic Valves -- 4.2. Vortex Formation in Presence of Mechanical Heart Valves (MHVs) -- 4.2.1. Study of MHVs’ Hemodynamics -- 4.2.2. Types of MHVs -- 4.2.3. Flow Across Mono-leaflet MHVs (MMHVs) -- 4.2.4. Orientation of MMHVs -- 4.2.5. Flow Across Bileaflet MHV (BMHV) -- 4.2.6. Consequence of Fluid Dynamics Experiments on Design of BMHVs -- 4.2.7. BMHVs at Aortic Position -- 4.2.8. BMHVs at Mitral Position -- 4.3. Vortical Flow Structures in Ventricular Assist Devices (VADs) -- 4.3.1. Classification of VADs -- 4.3.2. Pulsatile VAD Hemodynamics -- 4.3.3. Valves in the VAD -- 4.3.4. VAD Chamber -- 4.3.5. Continuous Flow VADs (CF VADs) -- 4.3.6. Hemodynamics of VADs Cannulation -- 4.4. Vortex Formation due to Arterial Surgery and Anastomosis -- 4.4.1. Fontan Procedure -- 4.4.2. Anastomoses -- References -- 5. Diagnostic Vortex Imaging -- 5.1. Magnetic Resonance Imaging -- 5.1.1. Velocity Measurements Using MRI -- 5.1.2. Visualization and Quantification -- 5.1.3. Future Developments -- 5.2. Echocardiography -- 5.2.1. Blood Flow Visualization Using Echocardiography -- 5.2.2. Color Doppler -- 5.2.3. Contrast Enhanced Imaging and Echo-PIV -- 5.2.4. Future Developments -- 5.3. In Vitro Experiments -- 5.3.1. Particle Image Velocimetry -- 5.3.2. Heart-Flow Simulator and Reproduction of Cardiac Cycles -- 5.3.3. Experimental Characterization of the Vortex Formation -- 5.3.4. Influence of Transmitral Vortex Formation on Mitral Annulus Dynamics -- 5.3.5. Conclusive Remarks -- 5.4. Numerical Simulation -- 5.4.1. Fundamentals Elements of Numerical Simulations -- 5.4.2. Fluid-Structure Interaction -- 5.5. Conclusion -- References.
- Format
- e-Book
- Location
- Online
