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Anticoagulation and Hemostasis in Neurosurgery

https://libcat.nshealth.ca/en/permalink/provcat40033
Christopher M. Loftus, editor. --Cham: Springer , c2016.
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This book is an up-to-date reference on all aspects of anticoagulation and hemostasis in neurosurgery. After an opening section on basic principles and drug classes in current use, detailed consideration is given to coagulation issues relevant to all patients, not just neurosurgical ones. The coverage includes, for example, deep vein thrombosis, pulmonary embolism, and disseminated intravascular coagulation. A variety of important issues specific to neurosurgical practice are then addressed, an…
Available Online
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Other Authors
Loftus, Christopher M
Responsibility
Christopher M. Loftus, editor
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2016
Physical Description
1 online resource (xi, 404 p. : 61 illus., 43 illus. in color)
ISBN
9783319273273
9783319273259 (print ed.)
Subjects (MeSH)
Anticoagulants - therapeutic use
Blood Coagulation Disorders - therapy
Blood Coagulation - drug effects
Blood Loss, Surgical - prevention & control
Hemostasis, Surgical
Neurosurgical Procedures
Perioperative Care
Abstract
This book is an up-to-date reference on all aspects of anticoagulation and hemostasis in neurosurgery. After an opening section on basic principles and drug classes in current use, detailed consideration is given to coagulation issues relevant to all patients, not just neurosurgical ones. The coverage includes, for example, deep vein thrombosis, pulmonary embolism, and disseminated intravascular coagulation. A variety of important issues specific to neurosurgical practice are then addressed, and the book concludes with a summary of current guidelines and best practices. As the population ages and prophylactic anticoagulation for different cardiac disorders is validated by cooperative trials, it is becoming ever more important that practicing neurosurgeons have the requisite knowledge to manage optimally the opposing processes of anticoagulation and hemostasis. Nevertheless, only a modest amount of structured information is at present available on the subject, with the consequence that decision making is too often insufficiently informed. This book, written by recognized experts, is designed to rectify this situation by bringing together the latest knowledge from across the entire discipline. It will be of daily value for neurosurgeons and trainees worldwide and will also be of interest to emergency room physicians, surgeons in general, critical care physicians, neurologists, and hospital medicine specialists.
Contents
Part 1. General Principles -- Physiology of Hemostasis -- Laboratory Assessment of Physiologic and Pathologic Hemostasis -- Current Anticoagulation Drugs and Mechanisms of Action -- Reversal of Target-Specific Oral Anticoagulants -- Overview, Treatment, Measurement, and Modification of Platelet Function -- Role of Antiplatelet Therapy in Neurosurgery: Efficacy and Safety Profiles -- Part 2. Coagulation Issues Across all Patient Spectrums -- Congenital Coagulation Disorders -- Acquired Coagulation Disorders -- Regulation and Dysregulation of Fibrinolysis -- Risks Associated with Administration of Allogeneic Blood Components -- Common Coagulation Disorders That May Arise Intraoperatively -- Evaluation and Management of Untoward Intraoperative Bleeding -- Treatment of Disseminated Intravascular Coagulation (DIC) -- Heparin-Induced Thrombocytopenia (HIT) -- Anticoagulation in Cardiovascular Diseases -- Workup and Treatment of Pulmonary Embolus -- Part 3. Coagulation Issues Specific to Neurosurgery -- Classes of Drugs and Blood Products for Acute Reversal of Anticoagulant Effect -- Rescue Strategies to Facilitate Emergency Neurosurgery in Patients on Antiplatelet or Anticoagulant Agents -- Considerations for Coagulation in the Multi-Trauma Patient -- Cerebral Venous Sinus Thrombosis -- Coagulation Studies in Preoperative Neurosurgery Patients -- Safe Strategies for Gradual Suspension and Re-institution of Anticoagulation to Permit Elective Surgery -- Spontaneous Intracerebral Hemorrhage due to Coagulation Disorders -- Prophylactic Screening for Venous Thromboembolism in Neurosurgical Patients -- Venous Thromboembolism Prophylaxis in Neurosurgery -- Can Patients with Known Intracranial and Intraspinal Vascular Lesions be Anticoagulated? -- Intrathecal Access and Devices in Patients on Antiplatelet or Anticoagulant Therapy -- Is it Safe to Shunt Anti-coagulated NPH Patients? -- Surgical Hemostasis in the Era of Anticoagulation: Guidelines and Recommendations Summary.
Format
e-Book
Location
Online
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The coagulation consult : a case-based guide

https://libcat.nshealth.ca/en/permalink/provcat33434
Alan Lichtin, John Bartholomew, editors. --New York: Springer , c2014.
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There have been many changes in the field of coagulation during the past decade. New concepts of epidemiology of risk factors for thrombosis now help clinicians predict who is more likely to form clots after surgery, or after being placed on oral contraceptives. New anticoagulants have the potential to redefine how patients with atrial fibrillation and venous thrombosis are managed. There are new forms of recombinant clotting factors which have changed our approach to hypofibrinogenemia and von…
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Other Authors
Lichtin, Alan
Bartholomew, John R
Responsibility
Alan Lichtin, John Bartholomew, editors
Place of Publication
New York
Publisher
Springer
Date of Publication
c2014
Physical Description
1 online resource (xii, 279 pages)
ISBN
9781461495604 (electronic bk.)
9781461495598
Subjects (MeSH)
Blood Coagulation Disorders - diagnosis
Blood Coagulation Disorders - therapy
Subjects (LCSH)
Blood coagulation disorders
Blood - Coagulation
Hematology
Oncology
Abstract
There have been many changes in the field of coagulation during the past decade. New concepts of epidemiology of risk factors for thrombosis now help clinicians predict who is more likely to form clots after surgery, or after being placed on oral contraceptives. New anticoagulants have the potential to redefine how patients with atrial fibrillation and venous thrombosis are managed. There are new forms of recombinant clotting factors which have changed our approach to hypofibrinogenemia and von Willebrand's disease. Newer antiplatelet agents are available and their use in patients receiving cardiac stents has mushroomed. The management of thrombosis in the setting of pregnancy has changed over the past decade, as well as the way clinicians approach women with multiple miscarriages. An entire new class of compounds, the thrombopoietins, are available to treat individuals with immune thrombocytopenic purpura (ITP). The Coagulation Consult covers major topics of interest to hematologists who are asked to consult on individuals with coagulation related diseases, and encompasses the field's most recent developments. This "case-directed" book describes state-of-the-art approaches to patients with bleeding and clotting disorders, as well as laboratory tests for coagulation. Chapters include different vignettes, focus on typical clinical consult questions, and lay out specific types of treatment. Practicing clinicians being confronted with a coagulation consult, students, residents, fellows and attending physicians will find this unique text an invaluable resource for some of the newer areas of coagulation science, therapy and pharmacology.
Contents
1. Laboratory Analysis of Coagulation -- 2. Easy Bruisability -- 3. Prolonged PT -- 4. Prolonged PTT -- 5. Prolongation of Both PT and aPTT -- 6. Excessive Bleeding with Normal Prothrombin Time, Partial Thromboplastin Time, and Platelet Count -- 7. Diagnosing Thrombocytopenia in the Clinic -- 8. Thrombocytopenia in the Intensive Care Unit and after Solid Organ Transplantation -- 9. Thrombocytosis -- 10. Prolonged Bleeding after Surgery -- 11. The Excessively Clotting Cancer Patient -- 12. Thrombotic Risk factors -- 13. Clotting around Catheters and Other Devices -- 14. Heparin-Induced Thrombocytopenia -- 15. Surgery on Patients on Antiplatelet Agents -- 16. Newer Oral Anticoagulants -- 17. Pregnancy.
Format
e-Book
Location
Online
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Hemostasis and thrombosis : practical guidelines in clinical management

https://libcat.nshealth.ca/en/permalink/provcat32843
edited by Hussain I. Saba, Harold R. Roberts. --Chichester, West Sussex, UK: John Wiley & Sons , c2014.
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Location
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Available Online
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Other Authors
Saba, Hussain I
Roberts, Harold R.
Responsibility
edited by Hussain I. Saba, Harold R. Roberts
Alternate Title
Haemostasis and thrombosis
Place of Publication
Chichester, West Sussex, UK
Publisher
John Wiley & Sons
Date of Publication
c2014
Physical Description
1 online resource (328 p.)
ISBN
9781118833421
Subjects (MeSH)
Blood Coagulation Disorders - therapy
Hemostatic Disorders - therapy
Thrombosis - therapy
Subjects (LCSH)
Blood coagulation disorders - Treatment
Hemostasis - Treatment
Thrombosis - Treatment
Blood Coagulation Disorders - therapy
Hemostatic Disorders - therapy
Thrombosis - therapy
Contents
Theories of blood coagulation : basic concepts and recent updates / Dougald M. Monroe, Maureane Hoffman -- Vascular endothelium, influence on hemostasis : past and present / Hussain I. Saba, Sabiha R. Saba -- Coagulation testing : basic and advanced clinical laboratory tests for the diagnosis of common hemostatic and thrombotic disorders / Nils Egberg and Margareta Blombäck -- Hemophilia A (factor VIII deficiency) : clinical bleeding and management / Pier Mannuccio Mannucci and Massimo Franchini -- Hemophilia B (factor IX deficiency) : clinical manifestations and management / R. S. Kasthuri, H. R. Roberts, P. E. Monahan -- Factor XI deficiency (hemophilia C) / Charles E. Bane, Anne T. Neff, and David Gailani -- Factor VIII and IX inhibitors in hemophilia / Meera Chitlur and Jeanne Lusher -- Treatment options for acquired hemophilia / Anjali Sharathkumar and David Green -- Factor XII deficiency (Hageman factor deficiency) / Evi Stavrou and Alvin H. Schmaier -- Inherited combined factor deficiency states / Asma Latif and Louis Aledort -- Acute and chronic ITP : biology, diagnosis, and management / Samir Dalia and Benjamin Djulbegovic -- Disseminated intravascular coagulation (DIC) : diagnosis and management / Stephanie J. Davis, Craig M. Kessler -- Mechanisms of fibrinolysis and basic principles of management / John W. Weisel and I. Litvinov -- Post thrombotic syndrome / Jean-Philippe Galanaud, Susan R. Kahn -- Von Willebrand disease : clinical aspects and practical management / Francesco Rodeghiero, Alberto Tosetto, Giancarlo Castaman -- Platelets in hemostasis : inherited and acquired qualitative disorders / Noman Ashraf and Hussain I. Saba -- Contributions of platelet polyphosphate to hemostasis and thrombosis / James H. Morrissey -- Thrombotic microangiopathy : thrombotic thrombocytopenic purpura and hemolytic uremic syndrome : biology, diagnosis, and management / Samir Dalia -- Hemostasis and aging / Lodovico Balducci -- Hemostatic problems in chronic and acute liver disease / Ton Lisman and Robert J. Porte -- Cancer and thrombosis / Erica Peterson and Agnes Lee -- An update on low-molecular-weight heparins / Jawed Fareed, Debra Hoppensteadt, Walter P. Jeske.
Format
e-Book
Location
Online
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