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edited by Felix Bronner, Mary C. Farach-Carson. --London: Springer-Verlag , c2009.
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Location
Online
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Author
Bronner, Felix
Other Authors
Farach-Carson, Mary C
Responsibility
edited by Felix Bronner, Mary C. Farach-Carson
Place of Publication
London
Publisher
Springer-Verlag
Date of Publication
c2009
Series Vol.
v. 5
Series Title
Topics in bone biology
ISBN
9781848820197
Subjects (MeSH)
Bone Marrow Neoplasms - physiopathology
Bone Marrow Neoplasms - secondary
Bone Marrow - pathology
Bone Neoplasms - physiopathology
Bone Neoplasms - secondary
Subjects (LCSH)
Oncology
Orthopedics
Format
e-Book
Location
Online
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Bone Metastasis : Experimental and Clinical Therapeutics

https://libcat.nshealth.ca/en/permalink/provcat29113
edited by Gurmit Singh, Shafaat A. Rabbani. --Totowa, NJ: Humana Press , c2005.
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Location
Online
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Author
Singh, Gurmit
Other Authors
Rabbani, Shafaat A
Responsibility
edited by Gurmit Singh, Shafaat A. Rabbani
Place of Publication
Totowa, NJ
Publisher
Humana Press
Date of Publication
c2005
Series Title
Cancer drug discovery and development
ISBN
9781592598922
Subjects (MeSH)
Bone Neoplasms - secondary
Neoplasm Metastasis
Subjects (LCSH)
Oncology
Orthopedics
Format
e-Book
Location
Online
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Metastatic Bone Disease : An Integrated Approach to Patient Care

https://libcat.nshealth.ca/en/permalink/provcat39684
R. Lor Randall, editor. (1st ed.) --New York, NY: Springer , c2016.
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Providing an integrated approach to the diagnosis and management of patients with metastatic bone disease (MBD), this comprehensive text combines discussion of the pathobiology of the disease with the latest oncological and orthopedic treatment modalities. After opening with an examination of the epidemiology and impact of MBD, the biology of bone metastases are discussed, along with considerations of the tissue of origin. Evaluation, biopsy and medical therapy, including metabolic agents and b…
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Other Authors
Randall, R. Lor
Responsibility
R. Lor Randall, editor
Edition
1st ed.
Place of Publication
New York, NY
Publisher
Springer
Date of Publication
c2016
Physical Description
1 online resource (xiii, 368 p. : 85 illus., 35 illus. in color)
ISBN
9781461456629
9781461456612 (print ed.)
Subjects (MeSH)
Bone Neoplasms - secondary
Bone Neoplasms - therapy
Abstract
Providing an integrated approach to the diagnosis and management of patients with metastatic bone disease (MBD), this comprehensive text combines discussion of the pathobiology of the disease with the latest oncological and orthopedic treatment modalities. After opening with an examination of the epidemiology and impact of MBD, the biology of bone metastases are discussed, along with considerations of the tissue of origin. Evaluation, biopsy and medical therapy, including metabolic agents and biotargeting. The heart of the book presents oncological approaches (supportive, radiation, and interventional) and principles of orthopedic surgical oncology, with subsequent chapters covering specific anatomy, from the pelvis to the lower extremity and the spine. Chapters on emerging surgical technology and future directions conclude the text and redefine an integrated approach to patient care. Taken together, Metastatic Bone Disease is an excellent resource for orthopedic surgeons and cancer specialists alike.
Contents
Part I. The Problem -- Bone Metastases: Epidemiology and Societal Effect -- Part II. Biology of Metastases and Tissue of Origin Considerations -- Pathobiology of Osteolytic and Osteoblastic Bone Metastases -- Biology of Bone Cancer Pain -- Breast Cancer Bone Metastases -- Prostate Cancer Bone Metastasis -- Lung -- Kidney Metastatic Bone Disease -- Thyroid -- Myeloma -- Part III. Work-Up for Patients with Suspected Metastatic Bone Disease -- Evaluation of the Patient with Carcinoma of Unknown Origin Metastatic to Bone -- Biopsy Considerations -- Part IV. Medical Therapy -- Bisphosphonates, Denosumab and Anabolic Agents in the Treatment of Metastatic Bone Disease -- Biotargeting in Metastatic Bone Disease -- Part V. Supportive Oncology -- Psychosocial Considerations for Patients with Metastatic Bone Disease -- Pain Management in Metastatic Bone Disease -- When is Hospice Appropriate? The Role for Hospice in Palliating Patients with Bone Metastases -- Part VI. Radiation Oncology -- Current and Emerging Modalities -- Part VII. Interventional Oncology -- Ablation and Cementation Technologies -- Part VIII. Principles of Orthopaedic Surgical Oncology -- Issues Facing the Established Metastatic Bone Disease Patient, Timing/Indications for Surgery -- Questions to Ask Your Medical Oncology Colleagues -- Consideration of the Temporal Relationship between Surgery and Radiation Therapy -- Role of Surgery in Oligometastatic Disease -- Part IX. Specific Anatomic Considerations for Surgery -- Metastatic Bone Disease: Pelvis -- Metastatic Bone Disease: Femur -- Metastatic Bone Disease: Femur: Tibia -- Metastatic Bone Disease: Foot -- Metastatic Bone Disease: Femur: Humerus, Scapula -- Metastatic Bone Disease: Forearm, Hand -- Metastatic Bone Disease: Spine -- Part X. Emerging Surgical Technologies -- Intraoperative Imaging and Navigation -- Part Eleven: Putting It All Together -- Integrative Approach with the Patient in Mind: A Glance Forward.
Format
e-Book
Location
Online
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Prevention of Bone Metastases

https://libcat.nshealth.ca/en/permalink/provcat31127
Markus Joerger, Michael Gnant, editors. --Berlin, Heidelberg: Springer , c2012.
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Bone metastases continue to be a major cause of morbidity in cancer patients, but improved understanding of the biology of bone metastases has led to the identification of drugs that are of potential value in not only their treatment but also their prevention. This book, written by recognized experts in the field, provides a detailed overview of current knowledge on this subject. One important focus of the book is the efficacy of bisphosphonates in preventing bone metastases in patients with br…
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Other Authors
Joerger, Markus
Gnant, Michael
Responsibility
Markus Joerger, Michael Gnant, editors
Place of Publication
Berlin, Heidelberg
Publisher
Springer
Date of Publication
c2012
Physical Description
1 online resource (ix, 233 p. : 23 ill., 13 ill. in color)
Series Vol.
192
Series Title
Recent results in cancer research
ISBN
9783642218927
Subjects (MeSH)
Biological Markers
Bone Neoplasms - prevention & control
Bone Neoplasms - secondary
Cytostatic Agents - therapeutic use
Diphosphonates - therapeutic use
Subjects (LCSH)
Oncology
Abstract
Bone metastases continue to be a major cause of morbidity in cancer patients, but improved understanding of the biology of bone metastases has led to the identification of drugs that are of potential value in not only their treatment but also their prevention. This book, written by recognized experts in the field, provides a detailed overview of current knowledge on this subject. One important focus of the book is the efficacy of bisphosphonates in preventing bone metastases in patients with breast, lung, and prostate cancer and disease progression in cases of multiple myeloma. The combined use of bisphosphonates and cytostatics is also discussed, with a report on first clinical data. Further topics addressed include the significance of the bone microenvironment, special issues in the elderly patient, the use of bone turnover markers, and initial findings obtained with denosumab.
Contents
Preclinical Models that Illuminate the Bone Metastasis Cascade -- The Role of Bone Microenvironment, Vitamin D and Calcium -- Bisphosphonates: Prevention of Bone Metastases in Breast Cancer -- Bisphosphonates: Prevention of Bone Metastases in Lung Cancer -- Bisphosphonates: Prevention of Bone Metastases in Prostate Cancer -- Targeting Bone in Myeloma -- Combinations of Bisphosphonates and Classical Anticancer Drugs: A Preclinical Perspective -- Perspectives in the Elderly Patient: Benefits and Limits of Bisphosphonates and Denosumab -- Denosumab: First Data and Ongoing Studies on the Prevention of Bone Metastases -- Diagnostic and Prognostic Use of Bone Turnover Markers -- Osteolytic and Osteoblastic Bone Metastases: Two Extremes of the Same Spectrum?
Format
e-Book
Location
Online
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Textbook of bone metastases

https://libcat.nshealth.ca/en/permalink/provcat22066
Jasmin, Claude. --Chichester, England: John Wiley and Sons , 2005.
Call Number
WE 258 T355 2005 REF
Location
Dickson Building
Sub-Location
REFERENCE
Call Number
WE 258 T355 2005 REF
Author
Jasmin, Claude
Place of Publication
Chichester, England
Publisher
John Wiley and Sons
Date of Publication
2005
Physical Description
568 p.
ISBN
0471877425
Subjects (MeSH)
Bone Neoplasms - secondary
Bone Neoplasms - therapy
Format
Book
Location
Dickson Building
Sub-Location
REFERENCE
Loan Period
In library use
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