topic:"Bone Neoplasms - therapy" found 5 records - Provincial Hospitals Library Catalogue

Bone Metastases from Prostate Cancer : Biology, Diagnosis and Management

https://libcat.nshealth.ca/en/permalink/provcat41417

Francesco Bertoldo, Francesco Boccardo, Emilio Bombardieri, Laura Evangelista, Riccardo Valdagni, editors. --Cham: Springer , 2017.

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Location: Online

This book presents up-to-date information on one of the hottest topics in prostate cancer, namely bone metastases. The most recent developments with respect to biology, pathology, diagnosis, and treatment are described, providing readers with an excellent understanding of the mechanisms of metastasis formation, the characteristics of metastases, their aggressiveness, and prognostic factors for treatment response. The coverage includes discussion of all of the best available options (laboratory,…

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Other Authors: Bertoldo, Francesco; Boccardo, Francesco; Bombardieri, Emilio; Evangelista, Laura; Valdagni, Riccardo

Responsibility: Francesco Bertoldo, Francesco Boccardo, Emilio Bombardieri, Laura Evangelista, Riccardo Valdagni, editors

Place of Publication: Cham

Publisher: Springer

Date of Publication: 2017

Physical Description: 1 online resource (x, 293 pages) : 63 illus., 40 illus. in color

ISBN: 9783319423272; 9783319423265 (print ed.)

Subjects (MeSH): Bone Neoplasms - diagnosis; Bone Neoplasms - therapy; Neoplasm Metastasis; Prostatic Neoplasms - pathology; Prostatic Neoplasms - therapy

Abstract: This book presents up-to-date information on one of the hottest topics in prostate cancer, namely bone metastases. The most recent developments with respect to biology, pathology, diagnosis, and treatment are described, providing readers with an excellent understanding of the mechanisms of metastasis formation, the characteristics of metastases, their aggressiveness, and prognostic factors for treatment response. The coverage includes discussion of all of the best available options (laboratory, radiology, and nuclear medicine) for achieving early diagnosis and both established and novel therapeutic approaches. Detailed information is provided on hormonal manipulations, bone-targeted agents, vaccines, taxanes, and other treatments that are enriching the therapeutic armamentarium. The editors can be considered leaders in the field, with great experience in diagnostic and clinical oncology and research, and the authors are experts in diverse specialties. This ensures a multidisciplinary approach, mirroring the current situation in which treatment in patients with bone metastases is undertaken by a team of specialists and health professionals in a variety of fields.

Contents: 1. Biology and Pathophysiology of Bone Metastasis in Prostate Cancer -- 2. Markers of Bone Turnover in Bone Metastasis from Prostate Cancer -- 3. Bone Homing and Metastasis -- 4. Markers of Prostate Cancer: The Role of Circulating Tumor Markers in the Management of Bone Metastases -- 5. Circulating Tumor Cells (CTCs) and Metastatic Prostate Cancer (mPCa) -- 6. Nuclear Medicine Modalities to Image Bone Metastases with Bone-Targeting Agents: Conventional Scintigraphy and Positron-Emission Tomography -- 7. Detection of Bone Metastases and Evaluation of Therapy Response in Prostate Cancer Patients by Radiolabelled Choline PET/CT -- 8. Imaging of Glycolysis with 18F- FDG PET -- 9. New Radiopharmaceutical Markers for Metabolism and Receptor -- 10. Bone Metastases from Prostate Cancer: Hormonal Therapy -- 11. Chemotherapy -- 12. Combinations of Hormonal Therapy and Chemotherapy -- 13. Surgery: Treatment of Oligometastatic Disease -- 14. Bone Metastases from Prostate Cancer: Radiotherapy -- 15. Bone-Targeted Agents -- 16. Bone-Seeking Radionuclide for Therapy -- 17. New Frontiers in Treatment -- 18. Approaches for Assessment of Response of Bone Metastases to Therapies -- 19. Bone Metastases from Prostate Cancer: From Symptom Control to Pain Palliation -- 20. Economic Impact of Prostate Cancer Bone Metastases -- 21. Multidisciplinary Approach of Prostate Cancer Patients.

Format: e-Book

Location: Online

Malignant Pediatric Bone Tumors - Treatment & Management

https://libcat.nshealth.ca/en/permalink/provcat39310

Timothy P. Cripe, Nicholas D. Yeager, editors. --Cham: Springer , c2015.

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Location: Online

This book describes in detail current best practice in the diagnosis and treatment of malignant pediatric bone tumors and also discusses other important aspects of management. Clinical assessment, the role of different imaging modalities, and choice of biopsy procedure are explained, and an individual chapter is devoted to diagnostic pathology. The treatment-oriented chapters offer in-depth descriptions of chemotherapeutic regimens, radiation therapy, limb-salvage options, and amputation-relate…

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Other Authors: Cripe, Timothy P; Yeager, Nicholas D

Responsibility: Timothy P. Cripe, Nicholas D. Yeager, editors

Place of Publication: Cham

Publisher: Springer

Date of Publication: c2015

Physical Description: 1 online resource (xii, 307 p. : 87 illus., 57 illus. in color)

Series Title: Pediatric oncology

ISBN: 9783319180991; 9783319180984 (print ed.)

ISSN: 1613-5318

Subjects (MeSH): Bone Neoplasms - therapy; Orthopedic Procedures - methods

Abstract: This book describes in detail current best practice in the diagnosis and treatment of malignant pediatric bone tumors and also discusses other important aspects of management. Clinical assessment, the role of different imaging modalities, and choice of biopsy procedure are explained, and an individual chapter is devoted to diagnostic pathology. The treatment-oriented chapters offer in-depth descriptions of chemotherapeutic regimens, radiation therapy, limb-salvage options, and amputation-related issues, and in addition consider the approach to lung nodules, the role of biomarkers, off-therapy monitoring, and the treatment of relapse. Psychosocial impacts and needs are addressed, and guidance provided on nursing during treatment and rehabilitation following orthopaedic surgery. Closing chapters evaluate emerging therapies and discuss disparate aspects of survivorship. The authors are acknowledged experts and include many contributors from the Nationwide Children's Hospital, a leading pediatric care facility in the United States.

Contents: Signs and symptoms -- Diagnostic Studies of Pediatric Bone Tumors: Pathology and Imaging -- Basic Principles of Biopsy -- The evaluation of lung nodules in pediatric bone tumors -- Fertility Preservation and Reproductive Health in Pediatric Bone Tumor Patients -- Chemotherapy Regimens for Patients with Newly Diagnosed Malignant Bone Tumors -- Radiation Management -- Histologic Response and Biologic Markers -- Surgical Approach: Limb Salvage Versus Amputation -- Rehabilitation following Orthopaedic Surgery in Children with Bone Tumors -- Patient Navigation of the Pediatric Bone Tumor Patient Across the Continuum of Care -- Psychosocial Effects of Pediatric Bone Tumors and Recommendations for Supportive Care -- Post-therapy surveillance of bone tumors -- Recurrent Bone Tumors -- Novel Therapies on the Horizon -- Survivorship.

Format: e-Book

Location: Online

Metastatic Bone Disease : An Integrated Approach to Patient Care

https://libcat.nshealth.ca/en/permalink/provcat39684

R. Lor Randall, editor. (1st ed.) --New York, NY: Springer , c2016.

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Location: Online

Providing an integrated approach to the diagnosis and management of patients with metastatic bone disease (MBD), this comprehensive text combines discussion of the pathobiology of the disease with the latest oncological and orthopedic treatment modalities. After opening with an examination of the epidemiology and impact of MBD, the biology of bone metastases are discussed, along with considerations of the tissue of origin. Evaluation, biopsy and medical therapy, including metabolic agents and b…

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Other Authors: Randall, R. Lor

Responsibility: R. Lor Randall, editor

Edition: 1st ed.

Place of Publication: New York, NY

Publisher: Springer

Date of Publication: c2016

Physical Description: 1 online resource (xiii, 368 p. : 85 illus., 35 illus. in color)

ISBN: 9781461456629; 9781461456612 (print ed.)

Subjects (MeSH): Bone Neoplasms - secondary; Bone Neoplasms - therapy

Abstract: Providing an integrated approach to the diagnosis and management of patients with metastatic bone disease (MBD), this comprehensive text combines discussion of the pathobiology of the disease with the latest oncological and orthopedic treatment modalities. After opening with an examination of the epidemiology and impact of MBD, the biology of bone metastases are discussed, along with considerations of the tissue of origin. Evaluation, biopsy and medical therapy, including metabolic agents and biotargeting. The heart of the book presents oncological approaches (supportive, radiation, and interventional) and principles of orthopedic surgical oncology, with subsequent chapters covering specific anatomy, from the pelvis to the lower extremity and the spine. Chapters on emerging surgical technology and future directions conclude the text and redefine an integrated approach to patient care. Taken together, Metastatic Bone Disease is an excellent resource for orthopedic surgeons and cancer specialists alike.

Contents: Part I. The Problem -- Bone Metastases: Epidemiology and Societal Effect -- Part II. Biology of Metastases and Tissue of Origin Considerations -- Pathobiology of Osteolytic and Osteoblastic Bone Metastases -- Biology of Bone Cancer Pain -- Breast Cancer Bone Metastases -- Prostate Cancer Bone Metastasis -- Lung -- Kidney Metastatic Bone Disease -- Thyroid -- Myeloma -- Part III. Work-Up for Patients with Suspected Metastatic Bone Disease -- Evaluation of the Patient with Carcinoma of Unknown Origin Metastatic to Bone -- Biopsy Considerations -- Part IV. Medical Therapy -- Bisphosphonates, Denosumab and Anabolic Agents in the Treatment of Metastatic Bone Disease -- Biotargeting in Metastatic Bone Disease -- Part V. Supportive Oncology -- Psychosocial Considerations for Patients with Metastatic Bone Disease -- Pain Management in Metastatic Bone Disease -- When is Hospice Appropriate? The Role for Hospice in Palliating Patients with Bone Metastases -- Part VI. Radiation Oncology -- Current and Emerging Modalities -- Part VII. Interventional Oncology -- Ablation and Cementation Technologies -- Part VIII. Principles of Orthopaedic Surgical Oncology -- Issues Facing the Established Metastatic Bone Disease Patient, Timing/Indications for Surgery -- Questions to Ask Your Medical Oncology Colleagues -- Consideration of the Temporal Relationship between Surgery and Radiation Therapy -- Role of Surgery in Oligometastatic Disease -- Part IX. Specific Anatomic Considerations for Surgery -- Metastatic Bone Disease: Pelvis -- Metastatic Bone Disease: Femur -- Metastatic Bone Disease: Femur: Tibia -- Metastatic Bone Disease: Foot -- Metastatic Bone Disease: Femur: Humerus, Scapula -- Metastatic Bone Disease: Forearm, Hand -- Metastatic Bone Disease: Spine -- Part X. Emerging Surgical Technologies -- Intraoperative Imaging and Navigation -- Part Eleven: Putting It All Together -- Integrative Approach with the Patient in Mind: A Glance Forward.