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Hypothermia and cerebral ischemia : mechanisms and clinical applications

https://libcat.nshealth.ca/en/permalink/provcat21538
Maier, Carolina M. --Totowa, NJ: Humana Press , 2004.
Call Number
WL 355 M217h 2004
Location
Halifax Infirmary
Call Number
WL 355 M217h 2004
Author
Maier, Carolina M
Other Authors
Steinberg, Gary K
Place of Publication
Totowa, NJ
Publisher
Humana Press
Date of Publication
2004
Physical Description
188 p.
ISBN
089603660X
Subjects (MeSH)
Hypothermia, Induced
Brain ischemia - therapy
Brain Injuries - therapy
Stroke - therapy
Format
Book
Location
Halifax Infirmary
Loan Period
3 weeks
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Giuseppe D’Aliberti, Marco Longoni, Cristina Motto, Valentina Oppo, Valentina Perini, Luca Valvassori, Simone Vidale. --Cham: Springer , 2017.
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Location
Online
This book provides detailed practical guidance on the management of acute ischemic stroke in the clinical settings encountered in daily practice. Real-life cases are used to depict a wide range of clinical scenarios and to highlight significant aspects of management of ischemic stroke. In addition, diagnostic and therapeutic protocols are presented and helpful decision-making algorithms are provided that are specific to the different professionals involved in delivery of acute stroke care and t…
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Author
D’Aliberti, Giuseppe
Other Authors
Longoni, Marco
Motto, Cristina
Oppo, Valentina
Perini, Valentina
Valvassori, Luca
Vidale, Simone
Responsibility
Giuseppe D’Aliberti, Marco Longoni, Cristina Motto, Valentina Oppo, Valentina Perini, Luca Valvassori, Simone Vidale
Place of Publication
Cham
Publisher
Springer
Date of Publication
2017
Physical Description
1 online resource (xiii, 91 pages) : 25 illus., 9 illus. in color
Series Title
Emergency Management in Neurology
ISBN
9783319317052
9783319317045 (print ed.)
ISSN
2367-1076
Subjects (MeSH)
Brain ischemia - diagnosis
Brain ischemia - therapy
Clinical Decision-Making
Emergency Treatment - methods
Stroke - diagnosis
Stroke - therapy
Abstract
This book provides detailed practical guidance on the management of acute ischemic stroke in the clinical settings encountered in daily practice. Real-life cases are used to depict a wide range of clinical scenarios and to highlight significant aspects of management of ischemic stroke. In addition, diagnostic and therapeutic protocols are presented and helpful decision-making algorithms are provided that are specific to the different professionals involved in delivery of acute stroke care and to differing types of hospital facility. The coverage is completed by the inclusion of up-to-date scientific background information relevant to diagnosis and therapy. Throughout, the approach adopted is both practical and multidisciplinary. The book will be of value for all practitioners involved in the provision of acute stroke care, and also for medical students.
Contents
Brief Description of Recent Developments in Diagnosis and Treatment -- Clinical Cases -- Organizational Clinical Pathways -- Differentiated Decisional Algorithms.
Format
e-Book
Location
Online
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Ischemic Stroke Therapeutics : A Comprehensive Guide

https://libcat.nshealth.ca/en/permalink/provcat39783
Bruce Ovbiagele, editor. (1st ed.) --Cham: Springer , c2016.
Available Online
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Location
Online
This complete resource captures state-of-the-art strategies and the accelerated pace of discovery that is revolutionizing what is known about ischemic stroke and its treatment. Therapeutics for acute management, secondary prevention, recovery, rehabilitation, asymptomatic cerebral ischemia, and implementation of stroke systems of care are all discussed in this comprehensive yet practical guide. Chapters are authored by leading academicians with extensive clinical practice experience from all ov…
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Other Authors
Ovbiagele, Bruce
Responsibility
Bruce Ovbiagele, editor
Edition
1st ed.
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2016
Physical Description
1 online resource (xiii, 322 p. : 89 illus., 49 illus. in color)
ISBN
9783319177502
9783319177496 (print ed.)
Subjects (MeSH)
Brain ischemia - therapy
Secondary Prevention - methods
Stroke - therapy
Abstract
This complete resource captures state-of-the-art strategies and the accelerated pace of discovery that is revolutionizing what is known about ischemic stroke and its treatment. Therapeutics for acute management, secondary prevention, recovery, rehabilitation, asymptomatic cerebral ischemia, and implementation of stroke systems of care are all discussed in this comprehensive yet practical guide. Chapters are authored by leading academicians with extensive clinical practice experience from all over the world and feature the scientific evidence behind prevailing therapeutic strategies for managing ischemic cerebrovascular disease. The specialist or general practitioner will gain critical knowledge in stroke management, current clinical challenges and promising new therapies under investigation.
Contents
1. General Concepts: Management of Acute Ischemic Stroke -- 2. Pre-hospital Stroke Treatment (EMS stabilization protocols) -- 3. Intravenous Thrombolysis and Anti-thrombotics -- 4. Intra-Arterial Therapy for Acute Ischemic Stroke -- 5. Hemicraniectomy -- 6. Supportive Care and Management of In-hospital Complications -- 7. Post-Discharge Complications of Stroke -- 8. General Concepts: Stroke Mechanisms, Subtyping, and Work Up -- 9. Traditional Stroke Risk Factor Treatment -- 10. Heterogeneous causes of stroke: Antithrombotics -- 11. Heterogeneous Causes of Stroke: Select Emerging Risk Factors -- 12. Secondary Prevention After Cardioembolic Stroke -- 13. Secondary Prevention after Ischemic Lacunar Stroke -- 14. Secondary Prevention after Symptomatic Large Artery Extracranial Disease -- 15. Secondary Prevention after Symptomatic Large Artery Intracranial Disease -- 16. Secondary Prevention after Non-atherosclerotic Cerebral Vasculopathies -- 17. Secondary Prevention after Ischemic Strokes due to Hypercoagulable States -- 18. General Concepts: Therapies for Rehabilitation and Recovery -- 19. Botulinum Toxin for Post-Stroke Limb Spasticity -- 20. Selective Serotonin Re-uptake Inhibitors -- 21. Constraint Induced Therapies -- 22. Virtual Reality in Stroke Rehabilitation -- 23. Transcranial Magnetic Stimulation -- 24. General Concepts: Management of Asymptomatic Cerebrovascular Disease -- 25. Asymptomatic Carotid Artery Stenosis -- 26. Subclinical Vascular Brain Injury -- 27. General Concepts: Stroke Systems of Care -- 28. Stroke Centers and Related Aspects of Stroke Systems -- 29. Role of Registries and Community Models in Developed Countries -- 30. Telemedicine in Stroke Systems of Care.
Format
e-Book
Location
Online
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Neuroprotective Therapy for Stroke and Ischemic Disease

https://libcat.nshealth.ca/en/permalink/provcat41539
Paul A. Lapchak, John H. Zhang, editors. --Cham: Springer , 2017.
Available Online
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Location
Online
This book is a critical and comprehensive look at current state-of-the-art scientific and translational research being conducted internationally, in both academia and industry; it serves to address new ways to provide effective treatment to victims of ischemic and hemorrhagic stroke and other ischemic diseases. Currently, stroke can be successfully treated through the administration of a thrombolytic, but the therapeutic window is short and many patients are not able to receive treatment. Only …
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Other Authors
Lapchak, Paul A.
Zhang, John H.
Responsibility
Paul A. Lapchak, John H. Zhang, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
2017
Physical Description
1 online resource (xvii, 795 pages) : 105 illus., 71 illus. in color
Series Title
Springer series in translational stroke research
ISBN
9783319453453
9783319453446 (print ed.)
ISSN
2363-958X
Subjects (MeSH)
Brain ischemia - therapy
Stroke - therapy
Neuroprotective Agents - therapeutic use
Abstract
This book is a critical and comprehensive look at current state-of-the-art scientific and translational research being conducted internationally, in both academia and industry; it serves to address new ways to provide effective treatment to victims of ischemic and hemorrhagic stroke and other ischemic diseases. Currently, stroke can be successfully treated through the administration of a thrombolytic, but the therapeutic window is short and many patients are not able to receive treatment. Only about 30% of patients are "cured" by available treatments. Divided into five sections, the proposed volume explores historical and novel neuroprotection mechanisms and targets, new and combination therapies, as well as clinical trial design for some of the most recent bench-side research.
Contents
Reflections on Neuroprotection Research and the Path Toward Clinical Success -- Systematic review & meta-analysis: important tools in understanding -- Neuroprotection is Technology, not Science -- History of Experimental Stroke Research -- History of Neuroprotection: Trials and Tribulations -- Targeting PSD-95 As a Novel Approach in the Treatment of Stroke -- ATP Sensitive Potassium Channels (KATP) Play a Role in Hypoxic Preconditioning against Neonatal Hypoxic-Ischemic Brain Injury -- Targeting Oxidative Stress in Stroke -- Nitrones, Old Fellows for New Therapies in Ischemic Stroke -- Neuroprotective strategies via modulation of innate immune receptors -- Harnessing the power of the human immune system via multi-omic immune profiling in stroke treatment and recovery -- Polarization of microglia/macrophages in brain ischemia: relevance for stroke therapy -- Endoplasmic Reticulum Stress: An Opportunity for Neuroprotective Strategies after Stroke -- Effects of Neuroprotectants before and after stroke: Statins and Anti-Hypertensives -- Toward Effective Combination Therapy and Pleiotropic Drugs -- TRPM7 Channels as Potential Therapeutic Targets for Stroke Cholinergic Protection in Ischemic Brain Injury -- Remote Ischemic Conditioning: A Highly Translatable Therapy for Acute Stroke -- Hypothermia for Acute Ischemic Stroke -- Modern endovascular treatment of ischemic disease -- Cerebral Microbleeds and Thrombolysis for Acute Ischemic Stroke -- Targeting pericytes and the microcirculation for ischemic stroke therapy -- Thrombolytic and Endovascular Therapies for Acute Ischemic Stroke -- Sonothrombolysis for acute ischemic stroke: a critical appraisal -- Combination Therapy with Thrombolysis -- Oxygen Carriers: Are they enough for cellular support? -- A new paradigm in protecting ischemic brain: preserving the neurovascular unit before reperfusion -- The right rodent for the job: infarct variability between strains and its impact on logistics of experimental animal studies -- Rabbit Spinal Cord Ischemia Model for the Development of Neuroprotective Treatments -- Stroke Sex Differences: from basic research to clinical trials -- Unpuzzling the co-morbid type 2 diabetes and hypertension-related cognitive dysfunction and stroke -- Sex Specific Factors in Stroke -- Current Imaging Strategies for Patient Selection in Acute Ischemic Stroke Trials.
Format
e-Book
Location
Online
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Stroke Recovery with Cellular Therapies

https://libcat.nshealth.ca/en/permalink/provcat29602
edited by Sean I. Savitz, Daniel M. Rosenbaum. --Totowa, NJ: Humana Press , c2008.
Available Online
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Location
Online
Available Online
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Author
Savitz, Sean I
Other Authors
Rosenbaum, Daniel M
Responsibility
edited by Sean I. Savitz, Daniel M. Rosenbaum
Place of Publication
Totowa, NJ
Publisher
Humana Press
Date of Publication
c2008
Series Title
Current clinical neurology
ISBN
9781603270571
Subjects (MeSH)
Brain ischemia - therapy
Intracranial hemorrhages - therapy
Stem cell transplantation - ethics
Stem cell transplantation - methods
Stroke - therapy
Subjects (LCSH)
Neurology
Transplantation of organs tissues etc
Format
e-Book
Location
Online
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Stroke Revisited : Diagnosis and Treatment of Ischemic Stroke

https://libcat.nshealth.ca/en/permalink/provcat41945
Seung-Hoon Lee, editor. --Singapore: Springer , 2017.
Available Online
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Location
Online
This book presents state of the art knowledge on stroke management in a unique organizational style. Ischemic stroke is extensively covered, with inclusion of overviews that dynamically describe all relevant diagnostic and therapeutic processes in a time sequence mirroring real practice. The individual components of management and key issues are fully discussed with the aid of complementary illustrations that facilitate understanding of practical aspects and enable the reader to retrieve fundam…
Available Online
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Other Authors
Lee, Seung-Hoon
Responsibility
Seung-Hoon Lee, editor
Place of Publication
Singapore
Publisher
Springer
Date of Publication
2017
Physical Description
1 online resource (xix, 379 pages) : 94 illus., 76 illus. in color
Series Title
Stroke revisited
ISBN
9789811014246
9789811014239 (print ed.)
Subjects (MeSH)
Brain ischemia - diagnosis
Brain ischemia - therapy
Stroke - diagnosis
Stroke - therapy
Abstract
This book presents state of the art knowledge on stroke management in a unique organizational style. Ischemic stroke is extensively covered, with inclusion of overviews that dynamically describe all relevant diagnostic and therapeutic processes in a time sequence mirroring real practice. The individual components of management and key issues are fully discussed with the aid of complementary illustrations that facilitate understanding of practical aspects and enable the reader to retrieve fundamental information quickly. In addition, the book considers the various causes of stroke and provides detailed guidance on means of secondary prevention. The recent demonstration of the substantial benefit of intra-arterial thrombectomy using stentrievers in patients with acute ischemic stroke represents a great moment in the history of stroke management. As we embark on a new era, there is an urgent need to review and evaluate current modalities for stroke diagnosis and treatment. In tackling this task, this book will be invaluable for physicians, angiographic interventionists, surgeons, and students seeking to acquire up-to-date knowledge on stroke.
Contents
Part I. Initial Assessment of Patients with Stroke-Like Symptoms -- 1. Stroke Center -- 2. Stroke Unit -- 3. Initial Assessment and Differential Diagnosis -- Part II. Diagnosis and Treatment of Stroke: Acute Stage -- 4. Overview of Patient Management Flow -- 5. Initial Diagnosis and Management of Acute Ischemic Stroke -- 6. Intravenous Thrombolysis for Acute Ischemic Stroke -- 7. History of Intra-arterial Thrombolysis -- 8. Mechanical Thrombectomy: New Era of Stent Retriever -- 9. Principles and Practical Application of Brain CT in Acute Ischemic Stroke -- 10. Principles and Practical Application of Brain MRI in Acute Ischemic Stroke -- 11. Identification of Stroke Mechanism: Stroke Classification -- 12. Selections of Antithrombotic Agents During Acute Stage -- 13. Ischaemic Stroke: Indication and Techniques of Decompressive Surgery -- 14. Critical and Medical Management in Acute Stage of Ischemic Stroke -- 15. Rehabilitation in Acute Stage -- Part III. Certain but Relatively Frequent Causes of Ischemic Stroke -- 16. Cerebral Venous Sinus Thrombosis -- 17. Stroke Caused by Cervical Artery Dissection -- 18. Antiphospholipid Antibody Syndrome -- 19. Cancer-Related Stroke -- 20. Moyamoya Disease -- 21. Central Nervous System Vasculitis -- 22. Genetic Causes of Ischemic Stroke -- Part IV. Secondary Prevention of Stroke -- 23. Identification of Vascular Risk Factors -- 24. Hypertension Management in Acute Ischemic Stroke -- 25. Diabetes Management After Stroke -- 26. Cholesterol Management After Stroke -- 27. Understanding Paradox of Risk Factors -- 28. Antithrombotics: Antiplatelet Drugs -- 29. Antithrombotics: Anticoagulants Including NOACs -- 30. Carotid Endarterectomy Versus Carotid Angioplasty and Stenting for Stroke Prevention -- 31. Post-Stroke Management: Emotional Disturbances and Pain -- 32. Identification of Vascular Cognitive Impairment -- 33. Rehabilitation in Subacute and Chronic Stage After Stroke -- Part V. Clinical Practice Guidelines -- 34. History, Purpose, and Use of Clinical Practice Guidelines for Stroke -- 35. Discrepancy and Pitfalls of Clinical Practice Guideline.
Format
e-Book
Location
Online
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6 records – page 1 of 1.