This book provides the reader with up-to-date information on important advances in the understanding of breast cancer and innovative approaches to its management. Current and emerging perspectives on genetics, biology, and prevention are first discussed in depth, and individual sections are then devoted to pathology, imaging, oncological surgery, plastic and reconstructive surgery, medical oncology, and radiotherapy. In each case the focus is on the most recent progress and/or state of the art …
This first of two fully updated volumes provides an in-depth account of breast disease characteristics, imaging and diagnosis. Covering from breast anatomy and tumor biology to benign and malignant lesions this is an indispensable companion for breast specialists, medical oncologists, radiologists and pathologists. The new edition contains chapters covering nuclear medicine iand a chapter explaining biostatistical and epidemiological terms and has been updated to reflect the latest changes in b…
This first of two volumes provides and in-depth account of breast disease characteristics, imaging and diagnosis. Covering from breast anatomy and tumor biology to benign and malignant lesions this is an indispensable companion for breast specialists, medical oncologists, radiologists and pathologists. The book is organised in themed parts exploring topics such as epidemiology, risk factors, genetic biomarkers, pathological evaluation of tumors and biopsy techniques. With a high number of color…
Now completely updated with the latest classifications of breast pathology and molecular diagnosis, David J. Dabbs’ Breast Pathology, 2nd Edition, remains your go-to source for integrated, comprehensive coverage of this fast-changing field. Written by internationally acclaimed pathologists, this definitive reference incorporates genomic and molecular information, clinical presentation, gross and microscopic pathologic findings, radiologic and laboratory diagnosis, immunohistochemistry, and the…
This book provides a concise, step-by-step guide to accurate microscopic diagnosis for clinicians who deal with patients with breast lesions. The emphasis is on a practical approach to dealing with breast biopsies and reaching a diagnosis. It outlines the procedures used for the microscopic diagnosis of various breast lesions and the significance of the nomenclature and terms used in pathology reports, including those dealing with uncommon or rare lesions. Ample illustrations of the lesions dis…
This book covers practical diagnostic issues in breast pathology, with special emphasis on areas which pose diagnostic difficulties. These include dealing with the gross specimens derived from patients treated with conservative surgery and those who had neo-adjuvant therapy before surgery. It also discusses how to deal with axillary lymph nodes, proliferative breast lesions, including DCIS, and problematic core biopsies, as well as fibro-epithelial, spindle cell, lobular, mucinous, metaplastic …
This first multi-authored work exclusively dedicated to breast lesions in core needle biopsy samples, A Comprehensive Guide to Core Needle Biopsies of the Breast is an all-inclusive textbook that provides an overview of the fundamentals of a breast core needle biopsy program, instructive topics on diagnostic approaches to breast core biopsies including a pattern-based strategy, and in-depth coverage of all entities commonly seen in the core biopsy setting. In addition, chapters detailing specia…
The Frozen Section Library series provides concise, user-friendly, site specific handbooks that are well illustrated and highlight the pitfalls, artifacts and differential diagnosis issues that arise in the hurried frozen section scenario. Frozen Section Library: Breast provides an easy reference and pocket book about the nuances of adequately handling breast specimens in a fashion that meets the increasingly complex environment of breast pathology. The pros and cons of frozen section versus u…
This text describes a system of reporting breast fine needle aspiration biopsy that uses five clearly defined categories, each described by a specific term and each with a specific risk of malignancy. The five categories are insufficient/inadequate, benign, atypical, suspicious of malignancy and malignant. Each category has a risk of malignancy and is linked to management recommendations, which include several options because it is recognized that diagnostic infrastructure, such as the availabi…
This book provides an up-to-date review of the risk factors and genetics influencing the development of this rare disease. This volume presents clinical features and recent advances in histopathology and molecular profiling are analysed, providing a valuable aid to clinicians in tailoring treatment to both the patient and the tumour. Readers will find important insights into the most effective strategies for making or negating a diagnosis of male breast cancer. Within this timely volume, consid…
Covering the history of breast cancer, theory of radiofrequency ablation (RFA), resection of carcinoma, imaging before and after non-surgical ablation therapy and quality of life, this book focuses on extensive breast-conserving treatment for the preservation of a cosmetically acceptable breast. It investigates the feasibility of percutaneous, minimally invasive techniques to ablate breast tumors and several modalities such as cryosurgery, laser ablation, thermoablation and high-intensity focus…
This book focuses on precursor lesions, borderline lesions, and early carcinomas of female-specific organs from the standpoint of pathology. In 2012, the latest WHO Classification of Tumours of the Breast, 4th ed., was published and subsequently, in 2014, the WHO Classification of Tumours of Female Reproductive Organs, 4th ed., was published. In these fourth editions, several new concepts are addressed that were not described in the previous editions, and many of them are related to the awarene…
This book presents the basic concepts for understanding and practicing breast pathology in routine practice. It explains how to tackle the diagnosis, emphasizing diagnostic clues for each entity as well as pitfalls and mimickers. Each chapter has concise, relevant text illustrated by numerous high-quality pictures highlighting the pearls and challenges in the diagnosis of breast lesions. Experts from around the world describe common and rarer conditions affecting the breast. Histology, immunohi…
This comprehensive volume reviews current topics and controversies in diagnostic breast pathology, and addresses frequently encountered diagnostic problems using a question and answer format and case presentations. Emphasis is placed on the diagnostic approach as it relates to morphology, clinical and radiographic correlation, differential diagnosis, and ancillary testing including immunohistochemical and molecular analyses. Answers are provided and serve as a practical, evidence-based, and pro…
This volume provides a comprehensive review of the molecular mechanisms involved in precancerous lesions and benign and malignant breast tumors. Given the complex molecular pathways in breast cancer biology, the book simplifies these complex mechanisms and highlights the practical issues important for daily practice. Sections are structured to review breast carcinogenesis and the role of familial predisposition and stem cells in initiation and progression of breast cancer. In-depth chapters pre…
WHO Classification of Tumours of the Breast is the fourth volume of the 4th Edition of the WHO series on histological and genetic typing of human tumours. This authoritative, concise reference book provides an international standard for oncologists and pathologists and will serve as an indispensable guide for use in the design of studies monitoring response to therapy and clinical outcome. Diagnostic criteria, pathological features, and associated genetic alterations are described in a strictl…