Advancing the Science of Cancer in Latinos
https://libcat.nshealth.ca/en/permalink/provcat44707
Amelie G. Ramirez, Edward J. Trapido, editors.
--Cham:
SpringerOpen
, c2020.
- Available Online
- View e-Book
- Access
- Open access
- Location
- Online
This open access book gives an overview of the sessions, panel discussions, and outcomes of the Advancing the Science of Cancer in Latinos conference, held in February 2018 in San Antonio, Texas, USA, and hosted by the Mays Cancer Center and the Institute for Health Promotion Research at UT Health San Antonio. Latinos – the largest, youngest, and fastest-growing minority group in the United States – are expected to face a 142% rise in cancer cases in coming years. Although there has been substa…
- Available Online
- View e-Book
- Other Authors
- Ramirez, Amelie G.
- Trapido, Edward J.
- Responsibility
- Amelie G. Ramirez, Edward J. Trapido, editors
- Place of Publication
- Cham
- Publisher
- SpringerOpen
- Date of Publication
- c2020
- Physical Description
- 1 online resource (xvii, 329 p.) : 18 illus., 13 illus. in color
- ISBN
- 9783030292867
- 9783030292850 (Print ed.)
- 9783030292874 (Print ed.)
- 9783030292881 (Print ed.)
- Subjects (MeSH)
- Health Policy
- Health Promotion
- Health Status Disparities
- Hispanic Americans
- Minority Health
- Neoplasms - ethnology
- Subjects (LCSH)
- Health promotion
- Oncology
- Social structure
- Social inequality
- Cancer research
- Other Subjects
- United States
- Specialty
- Population Health
- Abstract
- This open access book gives an overview of the sessions, panel discussions, and outcomes of the Advancing the Science of Cancer in Latinos conference, held in February 2018 in San Antonio, Texas, USA, and hosted by the Mays Cancer Center and the Institute for Health Promotion Research at UT Health San Antonio. Latinos – the largest, youngest, and fastest-growing minority group in the United States – are expected to face a 142% rise in cancer cases in coming years. Although there has been substantial advancement in cancer prevention, screening, diagnosis, and treatment over the past few decades, addressing Latino cancer health disparities has not nearly kept pace with progress. The diverse and dynamic group of speakers and panelists brought together at the Advancing the Science of Cancer in Latinos conference provided in-depth insights as well as progress and actionable goals for Latino-focused basic science research, clinical best practices, community interventions, and what can be done by way of prevention, screening, diagnosis, and treatment of cancer in Latinos. These insights have been translated into the chapters included in this compendium. The chapters summarize the presentations and include current knowledge in the specific topic areas, identified gaps, and top priority areas for future cancer research in Latinos. Advancing the Science of Cancer in Latinos proves to be an indispensable resource offering key insights into actionable targets for basic science research, suggestions for clinical best practices and community interventions, and novel strategies and advocacy opportunities to reduce health disparities in Latino communities. It will find an engaged audience among researchers, academics, physicians and other healthcare professionals, patient advocates, students, and others with an interest in the broad field of Latino cancer.
- Contents
- Part I. Introduction -- 1. Advancing the Science of Cancer in Latinos -- Part II. Genetics, Environment, Lifestyle, and Cancer -- 2. Disaggregated Hispanic Groups and Cancer: Importance, Methodology and Current Knowledge -- 3. Colorectal Cancer Disparities in Latinos: Genes vs. Environment -- Part III. Cancer Risk, Prevention, and Screening -- 4. Breast Cancer Risk and Mortality in Women of Latin American Origin -- 5. Prostate Cancer in U.S. Latinos: What Have We Learned and Where Should We Focus Our Attention -- 6. Differential Cancer Risk in Latinos: The Role of Diet -- Part IV. The Biology of Cancer Health Disparities -- 7. Biomarkers of Gastric Pre-Malignant Lesions -- 8. Molecular Subtypes and Driver Mutations in Latinos with Gastric Cancer: Implications for Etiological and Translational Research -- 9. The Biology of Breast Cancer Disparities in Hispanics: Current Knowledge, Gaps and Research Opportunities -- 10. Molecular Profiles of Breast Cancer in Hispanic/Latina -- Part V. Advances in Cancer Therapy and Clinical Trials -- 11. Biomarkers and Precision Medicine in Oncology Practice and Clinical Trials -- 12. Overcoming Barriers for Latinos on Cancer Clinical Trials -- Part VI. Cancer in the Era of Precision Medicine -- 13. Breast Cancer Precision Medicine in Hispanics/Latinas: Focus on Luminal B Tumors -- 14. Is Precision Medicine Widening Cancer Care Disparities in Latino Populations? The Rutgers Cancer Institute of New Jersey Experience -- Part VII. Cancer Outcomes and Survivorship in Latinos -- 15. A Vision for Improving Quality of Life Among Spanish-Speaking Latina Breast Cancer Survivors -- 16. Research Democracy in a Randomized Controlled Trial: Engaging Multiple Stakeholders in Patient-Centered Outcomes Research -- Part VIII. Engaging Latinos in Cancer Research -- 17. Es Tiempo: Engaging Latinas in Cervical Cancer Research -- 18. Reaching Latinos Through Social Media and SMS for Smoking Cessation -- 19. The Need for a Holistic Approach to Prevent Reproductive Cancers among US Latinas: The Potential Impact of Normalizing Sexuality and Improving Communication -- 20. Critical Steps for Engaging Hispanics in Cancer Research: Building Capacity to Enhance Participation in Biospecimen Donation with Hispanic Communities -- Part IX Charting the Future of Cancer Health Disparities Research in Latinos -- 21. Emerging Policies in US Health Care -- 22. A Way Forward: The Future of Cancer Health Disparities Research in Latinos.
- Access
- Open access
- Format
- e-Book
- Location
- Online
Cancer immunotherapy meets oncology : in honor of Christoph Huber
https://libcat.nshealth.ca/en/permalink/provcat33730
Cedrik Michael Britten, Sebastian Kreiter, Mustafa Diken, Hans-Georg Rammensee, editors.
--Heidelberg:
Springer
, c2014.
- Available Online
- View e-Book
- Location
- Online
This book provides a comprehensive update on the state of the art in cancer immunology, which has rapidly evolved from a field of clinical research into an established discipline of oncology. The key recent developments in immuno-oncology are all covered, from the ever-changing immunological and regulatory frameworks to the most promising therapeutic concepts. Themes include combination therapies and personalized medicine, as well as identification of biomarkers to guide the clinical developmen…
- Available Online
- View e-Book
- Other Authors
- Britten, Cedrik Michael
- Huber, Christoph
- Responsibility
- Cedrik Michael Britten, Sebastian Kreiter, Mustafa Diken, Hans-Georg Rammensee, editors
- Place of Publication
- Heidelberg
- Publisher
- Springer
- Date of Publication
- c2014
- Physical Description
- 1 online resource (ix, 248 pages)
- ISBN
- 9783319051048 (electronic bk.)
- 9783319051031
- Subjects (LCSH)
- Cancer - Immunotherapy
- Oncology
- Cancer Research
- Pharmacology/Toxicology
- Immunology
- Abstract
- This book provides a comprehensive update on the state of the art in cancer immunology, which has rapidly evolved from a field of clinical research into an established discipline of oncology. The key recent developments in immuno-oncology are all covered, from the ever-changing immunological and regulatory frameworks to the most promising therapeutic concepts. Themes include combination therapies and personalized medicine, as well as identification of biomarkers to guide the clinical development of new approaches and to pinpoint the optimal treatment for each patient. The book acknowledges the continuing dynamic nature of the field as reflected in the development of next-generation immunotherapies that are already in clinical testing. Cancer Immunotherapy Meets Oncology is dedicated to the lifetime achievements of Christoph Huber, founder and chair of the Association for Cancer Immunotherapy (CIMT). It is also a tribute to those researchers and clinicians who are striving to develop novel diagnostics and tailored immunotherapies for the benefit of cancer patients.
- Contents
- Part I. Immunological and Regulatory Framework for Immuno-oncology -- From Basic Immunology to New Therapies for Cancer Patients -- How T Cells Single Out Tumor Cells: "And That Has Made All the Difference" -- Effects of Regulatory T Cell-Dendritic Cell Interactions on Adaptive Immune Responses -- Evolution of the Regulatory Landscape for Immunomodulatory Compounds and Personalized Therapeutic Cancer Vaccines -- Immunoguiding, the Final Frontier in the Immunotherapy of Cancer -- Developing Cancer Immunotherapies as Drugs: Setting the Stage Through Methodological Progress -- Part II. Immunotherapies -- Reflections on Cancer Vaccines -- Dendritic Cell-Based Cancer Vaccines -- mRNA Vaccination and Personalized Cancer Therapy -- Antibody Therapy in Oncology -- Bispecific Antibodies for the Treatment of Cancer: The Challenges of Translation -- The ABCs of T Cell Receptor Gene Therapy -- The Express Drivers: Chimeric Antigen Receptor-Redirected T Cells Make It to the Clinic -- Part III. Cancer Entities -- Immunotherapy of Malignant Melanoma -- Prostate Cancer Vaccines Generated with the Disruptive RNActive® Technology Follow the Path Paved by Sipuleucel-T and Prostvac-VF -- Recent Developments in the Active Immunotherapy of Renal Cell Cancer -- Current Status of Immunotherapy in Gastroesophageal Cancer -- Non-small Cell Lung Cancer, NSCLC -- Towards More Specificity and Effectivity in the Antileukemia Immune Response -- Part IV. Biomarkers -- Molecular and Metabolic Cues of the Key-Lock Paradigm Dictating Immunogenic Cell Death -- Pathogenesis of Minimal Residual Disease: CTCs as Novel Biomarkers in Cancer Disease -- Genomics Meets Cancer Immunotherapy -- Part V. Featured Chapters -- Oncolytic Viruses -- Part VI. Final Remarks -- Final Words.
- Format
- e-Book
- Location
- Online
Cancer Research and Clinical Trials
https://libcat.nshealth.ca/en/permalink/chpams37357
Nova Scotia Health. Cancer Care Program.
[Halifax, NS]:
Nova Scotia Cancer Care Program
, 2018.
- Pamphlet Number
- 0029
- Available Online
- View Pamphlet
Clinical trials look at new treatments or a group of existing treatments in people with cancer. Many of today's treatments are the result of what we learned from other clinical trials. This pamphlet gives a summary of clinical trials dealing with cancer. This includes how they are developed, how you can take part, and the benefits of doing so.
- Available Online
- View Pamphlet
- Corporate Author
- Nova Scotia Health. Cancer Care Program
- Place of Publication
- [Halifax, NS]
- Publisher
- Nova Scotia Cancer Care Program
- Date of Publication
- 2018
- Format
- Pamphlet
- Language
- English
- Physical Description
- 1 electronic document (4 p.) : digital, PDF file
- Subjects (MeSH)
- Biomedical Research
- Clinical Trials as Topic
- Subjects (LCSH)
- Cancer--Research
- Clinical trials
- Medicine--Research
- Specialty
- Research
- Abstract
- Clinical trials look at new treatments or a group of existing treatments in people with cancer. Many of today's treatments are the result of what we learned from other clinical trials. This pamphlet gives a summary of clinical trials dealing with cancer. This includes how they are developed, how you can take part, and the benefits of doing so.
- Notes
- Patient & family guide
- Responsibility
- prepared by Nova Scotia Cancer Care Program
- Pamphlet Number
- 0029
Impact of energy balance on cancer disparities
https://libcat.nshealth.ca/en/permalink/provcat33884
Deborah J. Bowen, Gerald V. Denis, Nathan A. Berger, editors.
--Cham, Switzerland:
Springer
, c2014.
- Available Online
- View e-Book
- Location
- Online
This volume reviews disparities in cancer genetics, etiology, treatment and survivorship that are associated with differences in energy balance and how those differences and disparities may be affected by geography, socioeconomic status, ethnicity, biology, behavior and others. State-of-the-art strategies are outlined to alter these problems at the individual, community and policy levels. The book provides a comprehensive assessment of the multiple contributions of disparities in energy balance…
- Available Online
- View e-Book
- Other Authors
- Bowner, Deborah J.
- Denis, Gerald V.
- Berger, Nathan A.
- Responsibility
- Deborah J. Bowen, Gerald V. Denis, Nathan A. Berger, editors
- Place of Publication
- Cham, Switzerland
- Publisher
- Springer
- Date of Publication
- c2014
- Physical Description
- 1 online resource (xiii, 308 pages)
- Series Vol.
- v. 9
- Series Title
- Energy balance and cancer
- ISBN
- 9783319061030 (electronic bk.)
- 9783319061023
- Subjects (MeSH)
- Energy metabolism - physiology
- Health Status Disparities
- Neoplasms - ethnology
- Neoplasms - metabolism
- Obesity - complications
- Subjects (LCSH)
- Cancer - Research
- Abstract
- This volume reviews disparities in cancer genetics, etiology, treatment and survivorship that are associated with differences in energy balance and how those differences and disparities may be affected by geography, socioeconomic status, ethnicity, biology, behavior and others. State-of-the-art strategies are outlined to alter these problems at the individual, community and policy levels. The book provides a comprehensive assessment of the multiple contributions of disparities in energy balance and how they affect cancer. this volume should constitute a valuable resource to disparity focused investigators at all levels and serve s an important guide to professionals that deal with these issues, especially those who determine and implement policy.
- Contents
- Obesity and Cancer in Appalachia -- Disparities in Cancer Outcomes: A UK Perspective -- Behavioral Differences Leading to Disparities in Energy Balance and Cancer -- Impact of Obesity, Race, and Ethnicity on Cancer Survivorship -- The Biology of Aging: Role in Cancer, Metabolic Dysfunction, and Health Disparities -- Energy Balance and Multiple Myeloma in African Americans -- Single Nucleotide Polymorphisms in Obesity and Inflammatory Genes in African Americans with Colorectal Cancer -- Ethnic Differences in Insulin Resistance as a mediator of Cancer Disparities -- Role of Ethnic Differences in Mediators of Energy Balance -- Community-Based Strategies to Alter Energy Balance in Underserved Breast Cancer Survivors -- The Role of Policy in Reducing Inflammation -- Cancer Prevention through Policy Interventions that Alter Childhood Disparities in Energy.
- Format
- e-Book
- Location
- Online
Molecular testing in cancer
https://libcat.nshealth.ca/en/permalink/provcat33595
George M. Yousef, Serge Jothy, editors.
--New York:
Springer
, c2014.
- Available Online
- View e-Book
- Location
- Online
Molecular Testing in Cancer provides a state of the art review of clinically relevant molecular pathology in cancer. The book provides a brief, easy to read review of commonly employed diagnostic molecular techniques including recently developed "next generation" analytic tools, and offers a system-based run-through of the utility of molecular testing in individual cancer types, as well as reviewing current markers in cancer diagnosis, prognosis, and management. The volume also provides a prosp…
- Available Online
- View e-Book
- Other Authors
- Yousef, George M
- Jothy, Serge
- Responsibility
- George M. Yousef, Serge Jothy, editors
- Place of Publication
- New York
- Publisher
- Springer
- Date of Publication
- c2014
- Physical Description
- 1 online resource (xi, 442 pages)
- ISBN
- 9781489980502 (electronic bk.)
- 9781489980496
- Subjects (MeSH)
- Molecular Diagnostic Techniques
- Neoplasms - diagnosis
- Neoplasms - genetics
- Tumor Markers, Biological
- Subjects (LCSH)
- Cancer - Molecular diagnosis
- Pathology
- Laboratory Medicine
- Cancer Research
- Abstract
- Molecular Testing in Cancer provides a state of the art review of clinically relevant molecular pathology in cancer. The book provides a brief, easy to read review of commonly employed diagnostic molecular techniques including recently developed "next generation" analytic tools, and offers a system-based run-through of the utility of molecular testing in individual cancer types, as well as reviewing current markers in cancer diagnosis, prognosis, and management. The volume also provides a prospective for the future which includes recently characterized and emerging biomarkers.
- Contents
- Part I. Molecular Approaches and Techniques -- Transitioning Diagnostic Molecular Pathology to the Genomic Era: Cancer Somatic Mutation Panel Testing -- Conventional and Molecular Cytogenetics in Cancer -- Comparative Genomic Hybridization and Array Based CGH in Cancer -- Polymerase Chain Reaction -- Single Nucleotide Polymorphisms (SNPs) -- Clinical Application of DNA Sequencing: Sanger and Next-Generation Platforms -- Microarray-Based Investigations in Cancer -- Proteomics in Cancer Diagnostics -- Circulating Tumor Cells: A Noninvasive Liquid Biopsy in Cancer -- Molecular Applications in Various Malignancies -- Part II. Molecular Applications in Various Malignancies -- Molecular Testing in Hematologic Malignancies -- Molecular Testing in Breast Cancer -- Molecular Pathology of Gastrointestinal Tumors -- Molecular Testing in Pulmonary Tumors -- Molecular testing in Gynecological Malignancies -- Molecular Testing in CNS Tumors -- Molecular Testing in Adult Kidney Tumors -- Molecular Testing in Prostate Cancer -- Molecular Testing in Urothelial Tumors -- Molecular Testing in Thyroid Cancer -- Molecular Testing of Head and Neck Tumors -- Molecular Testing in Bone and Soft Tissue Tumors -- Molecular testing in Cutaneous Melanoma -- Molecular Testing in Paediatric Tumours -- Pharmacogenomics in Molecular Oncology -- Quality Assurance in Molecular Testing of Cancer.
- Format
- e-Book
- Location
- Online
Viruses and human cancer : from basic science to clinical prevention
https://libcat.nshealth.ca/en/permalink/provcat33319
Mei Hwei Chang, Kuan-Teh Jeang, editors.
--Heidelberg:
Springer
, c2014.
- Available Online
- View e-Book
- Location
- Online
Research on oncogenic viruses and related human cancers has advanced rapidly in the past decade. Most articles, however, focus on a specific oncogenic virus and cancer. There is consequently a need for a comprehensive, up-to-date monograph that offers broad and integrated knowledge. Viruses and Human Cancer From Basic Science to Clinical Prevention is designed to meet this need by providing an advanced overview on the basic and clinical aspects of oncogenic viruses and the human cancers that th…
- Available Online
- View e-Book
- Other Authors
- Chang, Mei Hwei
- Jeang, Kuan-Teh
- Responsibility
- Mei Hwei Chang, Kuan-Teh Jeang, editors
- Place of Publication
- Heidelberg
- Publisher
- Springer
- Date of Publication
- c2014
- Physical Description
- 1 online resource (viii, 290 pages)
- Series Vol.
- v. 193
- Series Title
- Recent results in cancer research
- ISBN
- 9783642389658 (electronic bk.)
- 9783642389641
- Subjects (LCSH)
- Oncogenic viruses
- Oncology
- Cancer Research
- Infectious Diseases
- Microbiology
- Abstract
- Research on oncogenic viruses and related human cancers has advanced rapidly in the past decade. Most articles, however, focus on a specific oncogenic virus and cancer. There is consequently a need for a comprehensive, up-to-date monograph that offers broad and integrated knowledge. Viruses and Human Cancer From Basic Science to Clinical Prevention is designed to meet this need by providing an advanced overview on the basic and clinical aspects of oncogenic viruses and the human cancers that they cause. Virology, virus-induced inflammation and tissue injuries, oncogenic mechanisms, epidemiology, and current and emerging preventive and therapeutic strategies are all discussed in detail. In addition, the book covers the individual aspects of seven oncogenic viruses, i.e., hepatitis B virus, hepatitis C virus, human papilloma virus, Epstein-Barr virus, human T-cell lymphotropic virus, Kaposi sarcoma-associated herpes virus, and Merkel cell polyomavirus, and the related human cancers. The susceptibility of high-risk hosts such as transplantation recipients is also addressed, and new vaccine developments are described.
- Contents
- Virus infection and human cancer : an overview -- Epidemiology of virus infection and human cancer -- Virus infection, inflammation and prevention of cancer -- The oncogenic role of hepatitis B virus -- Prevention of hepatitis B virus infection and liver cancer -- The oncogenic role of hepatitis C virus -- Prevention of hepatitis C virus infection and liver cancer -- The role of human papillomaviruses in oncogenesis -- Control of HPV infection and related cancer through vaccination -- Prevention and treatment for Epstein-Barr virus infection and related cancers -- HTLV-1 and leukemogenesis : virus-cell interactions in the development of adult T-cell leukemia -- Prevention of human T-cell lymphotropic virus Type 1 infection and adult T-cell leukemia/lymphoma -- Molecular biology of human herpesvirus 8 : novel functions and virus-host interactions implicated in viral pathogenesis and replication -- Anti-viral treatment and cancer control.
- Format
- e-Book
- Location
- Online
