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Abeloff's clinical oncology

https://libcat.nshealth.ca/en/permalink/provcat32179
[edited by] John E. Niederhuber, James O. Armitage, Michael B. Kastan ...[et al.]. (6th ed.) --Philadelphia, PA: Elsevier , c2020.
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Easily accessible and clinically focused, Abeloff's Clinical Oncology, 6th Edition, covers recent advances in our understanding of the pathophysiology of cancer, cellular and molecular causes of cancer initiation and progression, new and emerging therapies, current trials, and much more. Masterfully authored by an international team of leading cancer experts, it offers clear, practical coverage of everything from basic science to multidisciplinary collaboration on diagnosis, staging, treatment…
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Other Authors
Niederhuber, John E.
Responsibility
[edited by] John E. Niederhuber, James O. Armitage, Michael B. Kastan ...[et al.]
Edition
6th ed.
Alternate Title
Clinical oncology
Place of Publication
Philadelphia, PA
Publisher
Elsevier
Date of Publication
c2020
Physical Description
1 online resource, 2072 p.
ISBN
9780323476744
Subjects (MeSH)
Neoplasms - therapy
Medical Oncology - methods
Subjects (LCSH)
Oncology
Cancer--Treatment
Specialty
Medical Oncology
Abstract
Easily accessible and clinically focused, Abeloff's Clinical Oncology, 6th Edition, covers recent advances in our understanding of the pathophysiology of cancer, cellular and molecular causes of cancer initiation and progression, new and emerging therapies, current trials, and much more. Masterfully authored by an international team of leading cancer experts, it offers clear, practical coverage of everything from basic science to multidisciplinary collaboration on diagnosis, staging, treatment and follow up.
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Advances in diagnosis and management of ovarian cancer

https://libcat.nshealth.ca/en/permalink/provcat33783
Samir A. Farghaly, editor. --New York: Springer , c2014.
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This volume is an up-to-date resource on the international state-of-the-art in the diagnosis and management of ovarian cancer. While this devastating disease has been considered mainly a disease of the Western hemisphere, the book moves beyond our conventional understanding and embraces knowledge from around the world. It focuses on recent advances in diagnosis, including genetic screening; improvements and expanded choices in management, such as gene therapy and the optimization of chemotherap…
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Other Authors
Farghaly, Samir A
Responsibility
Samir A. Farghaly, editor
Place of Publication
New York
Publisher
Springer
Date of Publication
c2014
Physical Description
1 online resource (xv, 270 pages)
ISBN
9781461482710 (electronic bk.)
9781461482703
Subjects (MeSH)
Ovarian Neoplasms - diagnosis
Ovarian Neoplasms - therapy
Subjects (LCSH)
Ovaries - Cancer - Diagnosis
Ovaries - Cancer - Treatment
Oncology
Gynecology
Abstract
This volume is an up-to-date resource on the international state-of-the-art in the diagnosis and management of ovarian cancer. While this devastating disease has been considered mainly a disease of the Western hemisphere, the book moves beyond our conventional understanding and embraces knowledge from around the world. It focuses on recent advances in diagnosis, including genetic screening; improvements and expanded choices in management, such as gene therapy and the optimization of chemotherapeutic agents; and the latest laparoscopic and robotic surgical techniques. Further chapters address histopathologic features of this disease, and related psychosocial and quality of-life-issues.
Contents
1. Epidemiology of Ovarian Cancer: An Update -- 2. Genetic Risks of Ovarian Cancer -- 3. Ovarian Cancer Screening and Early Detection -- 4. Surface Epithelial Tumours of the Ovary -- 5. Pathology of Non-epithelial Malignancies of the Ovary -- 6. Strategies for the Management of Ovarian Cancer -- 7. Management of Hereditary Ovarian–Breast Cancer -- 8. Ovarian Cancer in the Pediatric Population -- 9. Management of Patients with Early-Stage Ovarian Cancer -- 10. Treatment of Advanced Stage Ovarian Cancer -- 11. Diagnosis and Management of Epithelial Ovarian Cancer with Peritoneal Metastases -- 12. Targeted Molecular Therapy for Patients with Ovarian Cancer -- 13. Psychological Aspects of Hereditary and Non-hereditary Ovarian Cancer -- 14. Quality of Life in Patients with Ovarian Cancer.
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e-Book
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ALERT – adverse late effects of cancer treatment. Volume 1, General concepts and specific precepts

https://libcat.nshealth.ca/en/permalink/provcat33390
Philip Rubin, Louis S. Constine, Lawrence B. Marks, editors. --Heidelberg: Springer , c2014.
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The literature on the late effects of cancer treatment is widely scattered in different journals since all major organ systems are affected and management is based on a variety of medical and surgical treatments. The aim of ALERT Adverse Late Effects of Cancer Treatment is to offer a coherent multidisciplinary approach to the care of cancer survivors. The central paradigm is that cytotoxic multimodal therapy results in a perpetual cascade of events that affects each major organ system different…
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Rubin, Philip
Constine, Louis S
Marks, Lawrence B
Responsibility
Philip Rubin, Louis S. Constine, Lawrence B. Marks, editors
Alternate Title
Adverse late effects of cancer treatment
Place of Publication
Heidelberg
Publisher
Springer
Date of Publication
c2014
Physical Description
1 online resource (xxiv, 311 pages)
Series
Medical radiology. Radiation oncology
Series Title
Medical radiology (Series)
ISBN
9783540723141 (electronic bk.)
9783540723134
Subjects (MeSH)
Antineoplastic Agents - adverse effects
Radiotherapy - adverse effects
Radiation Injuries
Subjects (LCSH)
Cancer - Treatment - Complications
Antineoplastic Agents - adverse effects
Radiotherapy - adverse effects
Abstract
The literature on the late effects of cancer treatment is widely scattered in different journals since all major organ systems are affected and management is based on a variety of medical and surgical treatments. The aim of ALERT Adverse Late Effects of Cancer Treatment is to offer a coherent multidisciplinary approach to the care of cancer survivors. The central paradigm is that cytotoxic multimodal therapy results in a perpetual cascade of events that affects each major organ system differently and is expressed continually over time. Essentially, radiation and chemotherapy are intense biologic modifiers that allow for cancer cure and cancer survivorship but accelerate senescence of normal tissues and increase the incidence of age-related diseases and second malignant tumors. Volume 1 of this two-volume work focuses on the general concepts and principles relevant to late effects and on the dynamic interplay of molecular, cytologic and histopathologic events that lead to altered physiologic and metabolic functions and their clinical manifestations. Chapters are also included on legal issues, economic aspects, nursing, psychological issues and quality of life.
Contents
Prologue: Surviving Cancer: SEER Statistics -- Biocontinuum of the Pathophysiology Paradigm -- Biophysiopathology of the Microvasculature and Microcirculation -- Molecular Mechanisms of Radiation Induced Injury -- Biodetection and Biointervention: Cytokine Pathways as a Rationale for Anti-Cytokine Interventions Post-Radiation -- Quantitative/Objective Analyses of RT-Induced Late Normal Tissue Injury Using Functional Imaging -- Biograding of Normal Tissue TNM Toxicity Taxonomy: Scoring the Adverse Effects of Cancer Treatment -- Understanding and Predicting Radiation-Associated Normal Tissue Injury: A Global and Historical Perspective -- Biotoxicity of Chemotherapy -- BioSurveillance and Longitudinal Lifelong Guidelines -- BioPediatric Complexities of Growth and Development -- BioGenetic and Host Implications -- Bioengineering of Irradiated Normal Tissues by Bone Marrow Stem Cells -- Radiotherapy-Induced Carcinogenesis and Leukemogenesis: Mechanisms and Quantitative Modeling -- The Bioepidemiology of MultiplePrimary Cancers -- Radiation-Related Second Primary Cancers: Clinical Perspectives -- The Psychosocial and Functional Impact of Radiation Therapy -- Nursing -- Economic Consequences of Late Effects -- Radiological and Nuclear Terrorism: Relevance to the Radiation Oncology and Biology Communities.
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e-Book
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ALERT – adverse late effects of cancer treatment. Volume 2, Normal tissue specific sites and systems

https://libcat.nshealth.ca/en/permalink/provcat33418
Philip Rubin, Louis S. Constine, Lawrence B. Marks, editors. --Heidelberg: Springer , c2014.
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The literature on the late effects of cancer treatment is widely scattered in different journals since all major organ systems are affected and management is based on a variety of medical and surgical treatments. The aim of ALERT Adverse Late Effects of Cancer Treatment is to offer a coherent multidisciplinary approach to the care of cancer survivors. The central paradigm is that cytotoxic multimodal therapy results in a perpetual cascade of events that affects each major organ system different…
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Other Authors
Rubin, Philip
Constine, Louis S
Marks, Lawrence B
Responsibility
Philip Rubin, Louis S. Constine, Lawrence B. Marks, editors
Alternate Title
Adverse late effects of cancer treatment
Place of Publication
Heidelberg
Publisher
Springer
Date of Publication
c2014
Physical Description
1 online resource (xx, 700 pages)
Series
Medical radiology. Radiation oncology
Series Title
Medical radiology (Series)
ISBN
9783540758631 (electronic bk.)
9783540758624
Subjects (MeSH)
Antineoplastic Agents - adverse effects
Radiotherapy - adverse effects
Radiation Injuries
Subjects (LCSH)
Cancer - Treatment - Complications
Neoplasms - therapy - complications
Abstract
The literature on the late effects of cancer treatment is widely scattered in different journals since all major organ systems are affected and management is based on a variety of medical and surgical treatments. The aim of ALERT Adverse Late Effects of Cancer Treatment is to offer a coherent multidisciplinary approach to the care of cancer survivors. The central paradigm is that cytotoxic multimodal therapy results in a perpetual cascade of events that affects each major organ system differently and is expressed continually over time. Essentially, radiation and chemotherapy are intense biologic modifiers that allow for cancer cure and cancer survivorship but accelerate senescence of normal tissues and increase the incidence of age-related diseases and second malignant tumors. Volume 2 of this two-volume work comprehensively documents potential late effects in all the normal tissue anatomic sites in the human body. The detection, diagnosis, management and prevention of effects are all considered in detail, and prognostic outcomes are discussed. Radiation risk factors and interactions with chemotherapy effects are clearly presented. The text is accompanied by numerous supportive illustrations and tables.
Contents
Brain and Cranial Nerves -- Spinal Cord and Peripheral Nervous System -- Neuroendocrine Complications of Radiation and Cancer Therapy -- Eye and Orbit -- Radiation-Induced Ototoxicity -- Late Oral Adverse Effects of Cancer Treatments -- Upper Respiratory and Digestive System: Pharynx, Larynx, and Xerostomia -- Thyroid -- Skin Surface, Dermis, and Wound Healing -- Breast Cancer -- Lung -- Heart, Coronary Arteries, Aorta and Great Vessels, Arteries and Veins, Microcirculation -- Esophagus -- Stomach, Small and Large Intestines -- Liver -- Adverse Late Effects of Radiation Treatment in the Pancreas -- Kidney and Ureter -- Urinary Bladder -- Prostate, Seminal Vesicle, Penis, and Urethra -- The Testes -- Ovary, Uterus (Fallopian Tube, Cervix), Vagina, and Vulva -- Radiation Induced Rectal Toxicity -- Musculoskeletal System: Growing Endochondral Bone, Mature Osseous, Muscle (Striated), and Soft Tissue Mesenchyme -- Hematopoietic System -- Late Effects of Hematopoietic Cell Transplantation Including Total Body Irradiation -- Lymph Nodes, Thymus, Spleen, and Lymphatics.
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e-Book
Location
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The breast : comprehensive management of benign and malignant diseases

https://libcat.nshealth.ca/en/permalink/provcat31489
[edited by] Kirby I. Bland, Edward M. Copeland III. (5th ed.) --Philadelphia, PA: Elsevier , c2018.
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Now in a single, convenient volume, The Breast: Comprehensive Management of Benign and Malignant Diseases, 5th Edition covers every clinically relevant aspect of the field: cancer, congenital abnormalities, hormones, reconstruction, anatomy and physiology, benign breast disease, and more. Building upon the strengths of previous editions, this updated volume by Drs. Kirby I. Bland, Edward M. Copeland III, V. Suzanne Klimberg, and William J Gradishar, includes the latest innovations in breast ca…
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Other Authors
Bland, K. I
Copeland, Edward M
Responsibility
[edited by] Kirby I. Bland, Edward M. Copeland III
Edition
5th ed.
Alternate Title
Breast
Place of Publication
Philadelphia, PA
Publisher
Elsevier
Date of Publication
c2018
Physical Description
1 online resource, 1136 p.
ISBN
9780323359559
Subjects (MeSH)
Breast diseases - therapy
Breast neoplasms - therapy
Subjects (LCSH)
Breast - Cancer - Treatment
Breast - Diseases - Treatment
Breast Diseases - therapy
Breast Neoplasms - therapy
Specialty
Gynecology
Medical Oncology
Abstract
Now in a single, convenient volume, The Breast: Comprehensive Management of Benign and Malignant Diseases, 5th Edition covers every clinically relevant aspect of the field: cancer, congenital abnormalities, hormones, reconstruction, anatomy and physiology, benign breast disease, and more. Building upon the strengths of previous editions, this updated volume by Drs. Kirby I. Bland, Edward M. Copeland III, V. Suzanne Klimberg, and William J Gradishar, includes the latest innovations in breast cancer detection and treatment in a practical, easy-to-use format ideal for today’s surgeons.
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Cancer-related fatigue

https://libcat.nshealth.ca/en/permalink/provcat33622
Joachim Weis, Markus Horneber. --Tarporley, England: Springer Healthcare , c2015.
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Cancer-related fatigue (CrF) is increasingly recognized as a significant problem for patients with cancer at all stages, including those undergoing therapy and in remission. In fact, studies have shown that CrF causes patients more distress than pain, nausea, or vomiting and yet fatigueáis still often undertreated and rarely studied. However, several new treatments such as are being investigated to determine the most effective ways to manage this debilitating symptom and improve patient quality…
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Author
Weis, Joachim
Other Authors
Horneber, Markus
Responsibility
Joachim Weis, Markus Horneber
Place of Publication
Tarporley, England
Publisher
Springer Healthcare
Date of Publication
c2015
Physical Description
1 online resource (vii, 74 pages)
ISBN
9781907673764 (electronic bk.)
9781907673757
Subjects (MeSH)
Fatigue
Neoplasms - complications
Subjects (LCSH)
Cancer - Treatment - Complications
Fatigue - Pathophysiology
Fatigue - Physiological aspects
Abstract
Cancer-related fatigue (CrF) is increasingly recognized as a significant problem for patients with cancer at all stages, including those undergoing therapy and in remission. In fact, studies have shown that CrF causes patients more distress than pain, nausea, or vomiting and yet fatigueáis still often undertreated and rarely studied. However, several new treatments such as are being investigated to determine the most effective ways to manage this debilitating symptom and improve patient quality of life. Cancer-Related Fatigue will provide a concise overview of this condition, with an evidence-based discussion of diagnosis, treatment, and long-term management.
Contents
Introduction -- Etiology and pathogenetic factors -- Nonpharmacological treatment of cancer-related fatigue -- Pharmacological treatment of cancer-related fatigue -- Recommendations for the management of cancer-related fatigue.
Format
e-Book
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Clinical gynecologic oncology

https://libcat.nshealth.ca/en/permalink/provcat31877
[edited by] Philip J. DiSaia, William T. Creasman, Robert S. Mannell, Scott McMeekin, David G. Mutch. (9th ed.) --Philadelphia, PA: Elsevier , c2018.
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Other Authors
Di Saia, Philip J
Creasman, William T
Responsibility
[edited by] Philip J. DiSaia, William T. Creasman, Robert S. Mannell, Scott McMeekin, David G. Mutch
Edition
9th ed.
Alternate Title
Clinical gynaecologic oncology
Place of Publication
Philadelphia, PA
Publisher
Elsevier
Date of Publication
c2018
Physical Description
1 online resource
ISBN
978032340067 (electronic bk.)
Subjects (MeSH)
Genital Neoplasms, Female
Gynecology
Subjects (LCSH)
Generative organs, Female - Cancer - Diagnosis
Generative organs, Female - Cancer - Treatment
Genital Neoplasms, Female
Specialty
Gynecology
Medical Oncology
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Combination Therapy

https://libcat.nshealth.ca/en/permalink/chpams37337
Nova Scotia Health. Cancer Care Program. [Halifax, NS]: Nova Scotia Cancer Care Program , 2018.
Pamphlet Number
0004
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Combination therapy is when more than one cancer treatment is used. This pamphlet lists the different types of treatments and introduces why each one may be used with direction to more information. It lists suggested questions to ask your health care team.
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Corporate Author
Nova Scotia Health. Cancer Care Program
Place of Publication
[Halifax, NS]
Publisher
Nova Scotia Cancer Care Program
Date of Publication
2018
Format
Pamphlet
Language
English
Physical Description
1 electronic document (4 p.) : digital, PDF file
Subjects (MeSH)
Combined Modality Therapy
Neoplasms - therapy
Subjects (LCSH)
Cancer--Treatment
Combined modality therapy
Specialty
Medical Oncology
Therapeutics
Abstract
Combination therapy is when more than one cancer treatment is used. This pamphlet lists the different types of treatments and introduces why each one may be used with direction to more information. It lists suggested questions to ask your health care team.
Notes
Patient & family guide
Responsibility
prepared by Nova Scotia Cancer Care Program
Pamphlet Number
0004
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Controversies in the management of gynecological cancers

https://libcat.nshealth.ca/en/permalink/provcat33707
Jonathan A. Ledermann, Carien L. Creutzberg, Michael A. Quinn, editors. --London: Springer , c2014.
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Gynecological cancers are some of the most commonly occurring malignancies in women. Despite their high incidence, treatment and management of these cancers remain controversial, with conflicting evidence about many aspects of the disease. Controversies in the Management of Gynecological Cancers offers a unique assessment of the opposing sides of the controversial issues associated with gynecological cancers, and aims to provide professionals in the field with a keener sense of the underlying e…
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Other Authors
Ledermann, Jonathan A
Creutzberg, Carien L
Quinn, Michael A
Responsibility
Jonathan A. Ledermann, Carien L. Creutzberg, Michael A. Quinn, editors
Place of Publication
London
Publisher
Springer
Date of Publication
c2014
Physical Description
1 online resource (xv, 349 pages)
ISBN
9780857299109 (electronic bk.)
9780857299093
Subjects (MeSH)
Antineoplastic Agents - therapeutic use
Combined Modality Therapy
Genital Neoplasms, Female - diagnosis
Genital Neoplasms, Female - therapy
Outcome and Process Assessment (Health Care)
Subjects (LCSH)
Generative organs, Female - Cancer - Treatment
Genital Neoplasms, Female - therapy
Abstract
Gynecological cancers are some of the most commonly occurring malignancies in women. Despite their high incidence, treatment and management of these cancers remain controversial, with conflicting evidence about many aspects of the disease. Controversies in the Management of Gynecological Cancers offers a unique assessment of the opposing sides of the controversial issues associated with gynecological cancers, and aims to provide professionals in the field with a keener sense of the underlying evidence-base and a starting point from which to follow the ongoing debate. A section on the direction of future research to resolve these issues completes the discussion in each chapter. This book will appeal to specialists, trainees and healthcare workers in gynecological oncology, gynecologists, medical oncologists and radiation oncologists, and is an excellent starting point for anyone who wishes to gain a better understanding of the complex nature of the management of gynecological malignancy.
Contents
1. Controversies in the Treatment of Women with Early Stage Epithelial Ovarian Cancer -- 2. Recurrent Ovarian Cancer: When to Treat and How to Assess -- 3. New Views of Ovarian Carcinoma Types: How will this Change Practice? -- 4. Lymphadenectomy in Endometrial Cancer: The Controversy Rages Unabated -- 5. What is the Role of Adjuvant Radiotherapy and Chemotherapy in Endometrial Cancer? -- 6. Chemotherapy and/or Targeted Therapies for Advanced Endometrial Cancer: Time to Rethink? -- 7. Is Cervix Cancer a Disappearing Disease? Impact of HPV Vaccination in Developed Countries -- 8. What is the Role of Cytotoxic Chemotherapy in Advanced Cervical Cancer? -- 9. Response as a Measure of Treatment Efficacy in Clinical Trials: Should RECIST Be Abandoned? -- 10. What are the Treatment Options for Recurrent Ovarian Cancer? -- 11. How To Study Rare Gynaecological Tumours: Trials or Registries? -- 12. What is the Best Treatment Model for Gynaecological Cancers? Does Centralization Help? -- 13. When Should Surgery be Performed for the First-Line Treatment of Advanced Ovarian Cancer? -- 14. Does Intraperitoneal Therapy for Ovarian Cancer have a Future? -- 15. Maintenance Therapy for First-Line Treatment of Ovarian CancerIs this the Strategy for the Future? -- 16. What is the Value of Lymphadenectomy in Early Ovarian Cancer? -- 17. Sentinel Node BiopsyDoes it Help in the Management of Vulvar Cancer? -- 18. Controversies in the Management of Advanced Vulvar Cancer -- 19. Bowel Obstruction in Ovarian Cancer: To Operate or Not? -- 20. Early Cervical Cancer: Can Fertility be Safely Preserved? -- 21. What is the Role of PET/CT in Gynaecologic Cancers? -- 22. Do Intensity-Modulated Radiation, Image-Guided Radiation, and 3D Brachytherapy Significantly Advance Radiotherapeutic Management of Gynecologic Cancers? -- 23. What is the Place of Hormone Replacement Therapy in Ovarian, Endometrial, and Breast Cancer? -- 24. Familial Gynaecological Cancers: Whom to Screen and How to Manage? -- 25. Trial Design: Should Randomized Phase III Trials in Gynaecological Cancers be Abandoned? -- 26. How Should Early Gestational Trophoblastic Disease be Managed? -- 27. Should Every Woman with Gynaecologic Cancer Undergo Routine Screening for Psychological Distress and Sexual Dysfunction? -- 28. How Should Gynaecological Sarcomas be Managed? -- 29. What is the Future of Immunotherapy in Ovarian Cancer?
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e-Book
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DNA repair in cancer therapy : molecular targets and clinical applications

https://libcat.nshealth.ca/en/permalink/provcat31672
edited by Mark R. Kelley and Melissa L. Fishel. (2nd ed.) --London, UK: Academic Press , c2016.
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Other Authors
Kelley, Mark R
Fishel, Melissa L
Responsibility
edited by Mark R. Kelley and Melissa L. Fishel
Edition
2nd ed.
Place of Publication
London, UK
Publisher
Academic Press
Date of Publication
c2016
Physical Description
1 online resource, 444 p.
ISBN
9780128035825
Subjects (MeSH)
DNA Repair
DNA, neoplasm
Subjects (LCSH)
DNA Repair
Neoplasms - drug therapy
Neoplasms - genetics
DNA repair
Cancer - Treatment
Antimutagens - Therapeutic use
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Early neoplasias of the gastrointestinal tract : endoscopic diagnosis and therapeutic decisions

https://libcat.nshealth.ca/en/permalink/provcat33875
Frieder Berr, Tsuneo Oyama, Thierry Ponchon, Naohisa Yahagi, editors. --New York: Springer , c2014.
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Early Neoplasias of the Gastrointestinal Tract: Endoscopic Diagnosis and Therapeutic Decisions is an update of the current standards and newest skills in diagnostic endoscopy for neoplastic lesions of the upper and lower gastrointestinal tract. The volume defines strategies for detection and endoscopic assessment of small and minute early cancers and precursor lesions, including the endoscopic and endosonographic criteria for submucosal invasiveness. The book provides the knowledge in novel mag…
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Other Authors
Oyama, Tsuneo
Ponchon, Thierry
Yahagi, Naohisa
Berr, F.
Responsibility
Frieder Berr, Tsuneo Oyama, Thierry Ponchon, Naohisa Yahagi, editors
Place of Publication
New York
Publisher
Springer
Date of Publication
c2014
Physical Description
1 online resource (xiii, 270 pages)
ISBN
9781461482925 (electronic bk.)
9781461482918
Subjects (MeSH)
Diagnosis, Differential
Early Detection of Cancer
Endoscopy, Gastrointestinal
Gastrointestinal Neoplasms - diagnosis
Gastrointestinal Tract - cytology
Subjects (LCSH)
Gastrointestinal system - Cancer - Diagnosis
Gastrointestinal system - Cancer - Endoscopic surgery
Gastrointestinal system - Cancer - Treatment
Gastroenterology
Oncology
Abdominal surgery
Colorectal Surgery
Minimally Invasive Surgery
Abstract
Early Neoplasias of the Gastrointestinal Tract: Endoscopic Diagnosis and Therapeutic Decisions is an update of the current standards and newest skills in diagnostic endoscopy for neoplastic lesions of the upper and lower gastrointestinal tract. The volume defines strategies for detection and endoscopic assessment of small and minute early cancers and precursor lesions, including the endoscopic and endosonographic criteria for submucosal invasiveness. The book provides the knowledge in novel magnifying endoscopic analysis of early neoplasias fundamental to differential indication on snare mucosectomy, endoscopic submucosal dissection, or surgical/laparoscopic full-wall resection. Differential indications and contraindications for each technique are also specified.
Contents
Part I. General Principles of Endoscopy for Early Gastrointestinal Neoplasias -- Endoscopic Screening and Surveillance: Indications and Standards -- Histopathology of Early Mucosal Neoplasias: Morphologic Carcinogenesis in the GI Tract -- Principles of Endoscopic Resection: Diagnostic and Curative Resection of Mucosal Neoplasias -- Endoscopic Detection and Analysis of Mucosal Neoplastic Lesions -- Endoscopic Detection and Analysis of Mucosal Neoplastic Lesions: Enhanced Imaging and Tumor Morphology -- High-resolution Endoscopic Ultrasound: Clinical T-staging of Mucosal Neoplasms -- Part II. Organ-Specific Endoscopic Analysis of Early Neoplasias -- Squamous Cell-lined Esophagus and Hypopharynx: Mucosal Neoplasias -- Columnar Epithelium-lined (Barretts) Esophagus: Mucosal Neoplasias -- Stomach: Mucosal Neoplasias -- Duodenum and Small Bowel: Mucosal Neoplasias -- Colorectum: Mucosal Neoplasias -- Chronic Inflammatory Bowel Disease in Remission: Mucosal Neoplasias -- Appendix: Terminology (Proposed Throughout the Book).
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e-Book
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Online
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Epigenetic therapy of cancer : preclinical models and treatment approaches

https://libcat.nshealth.ca/en/permalink/provcat33709
Michael Lübbert, Peter A. Jones, editors. --Heidelberg: Springer , c2014.
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The growing knowledge about disturbances of epigenetic gene regulation in hematopoietic stem cell disorders such as myeloid leukemias and preleukemias (myelodysplasias) is now being translated into treatment approaches that target the epigenetic defects pharmacologically. Such approaches include reactivation of tumor suppressor genes and other antiproliferative genes by reversal of DNA hypermethylation through azanucleosides, and use of HDAC inhibitors to reverse gene silencing mediated by chim…
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Lübbert, Michael
Jones, P. A
Responsibility
Michael Lübbert, Peter A. Jones, editors
Place of Publication
Heidelberg
Publisher
Springer
Date of Publication
c2014
Physical Description
1 online resource (x, 325 pages)
ISBN
9783642384042 (electronic bk.)
9783642384035
Subjects (MeSH)
DNA Methylation - genetics
Epigenesis, Genetic - physiology
Genetic therapy
Methyltransferases - antagonists & inhibitors
Neoplasms - genetics
Neoplasms - therapy
Subjects (LCSH)
Cancer - Treatment
Cancer - Genetic aspects
Neoplasms - therapy
Neoplasms - genetics
Abstract
The growing knowledge about disturbances of epigenetic gene regulation in hematopoietic stem cell disorders such as myeloid leukemias and preleukemias (myelodysplasias) is now being translated into treatment approaches that target the epigenetic defects pharmacologically. Such approaches include reactivation of tumor suppressor genes and other antiproliferative genes by reversal of DNA hypermethylation through azanucleosides, and use of HDAC inhibitors to reverse gene silencing mediated by chimeric, leukemia-specific transcription factors. This book first presents the latest evidence derived from preclinical models regarding the epigenetic regulation of hematopoietic stem cell differentiation and hemoglobin production. The significance of DNA methylation abnormalities in hematopoietic disorders and of epigenetic disturbances in lung cancer and other solid tumors is then discussed. A major part of the book, however, relates specifically to the translation of basic research and drug development to clinical applications, and in this context both present and future clinical strategies are considered. Individual chapters are devoted to the use of DNA hypomethylating agents and chromatin-modifying agents, and the treatment of hematologic malignancies and solid tumors by means of epigenetic agents is discussed in detail.
Contents
The fundamental role of epigenetic regulation for normal and disturbed all growth and differentiation -- Mouse models to study DNA methylation in cancer research -- Epigenetic regulation of normal hematopoietic development -- Epigenetic regulation of globin genes and disturbances in hemoglobinopathies -- DNA methylation abnormalities in hematopoietic disorders: biological significance and methodological approaches -- Epigenetic modifications mediated by the AML1/ETO and MLL leukemia fusion proteins -- Epigenetic abnormalities in lung cancer -- Pharmacodynamic responses to DNA methyltransferase inhibition -- Histone methyltransferases: opportunities in cancer drug discovery -- Histone deacetylase (HDAC) inhibitors in recent clinical trials for cancer therapy -- Clinical implications of epigenetic alterations in lung cancer -- Epigenetic disturbances in colorectal cancer -- Epigenetic therapies in solid tumours: from preclinical models to clinical trial results.
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e-Book
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Guide to targeted therapies : EGFR mutations in NSCLC

https://libcat.nshealth.ca/en/permalink/provcat33463
Federico Cappuzzo. --Cham, Switzerland: Springer , c2014.
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Guide to Targeted Therapies: EGFR Mutations in NSCLC is a speedy and up-to-date review, which discusses EGFR mutations, testing methods and technology, current and emerging therapies, and resources that clinicians can provide to their patients. Busy healthcare professionals who want a quick review of EGFR gene mutations as well as a summary of current therapies will benefit from this succinct guide.
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Author
Cappuzzo, Federico
Responsibility
Federico Cappuzzo
Place of Publication
Cham, Switzerland
Publisher
Springer
Date of Publication
c2014
Physical Description
1 online resource (xi, 67 pages)
ISBN
9783319030593 (electronic bk.)
9783319030586
Subjects (MeSH)
Carcinoma, Non-Small-Cell Lung - genetics
Carcinoma, Non-Small-Cell Lung - therapy
Epidermal Growth Factor - physiology
Lung Neoplasms - genetics
Receptor, Epidermal Growth Factor - physiology
Subjects (LCSH)
Lungs - Cancer - Treatment
Epidermal growth factor
Abstract
Guide to Targeted Therapies: EGFR Mutations in NSCLC is a speedy and up-to-date review, which discusses EGFR mutations, testing methods and technology, current and emerging therapies, and resources that clinicians can provide to their patients. Busy healthcare professionals who want a quick review of EGFR gene mutations as well as a summary of current therapies will benefit from this succinct guide.
Contents
1. Introduction -- 2. The Human Epidermal growth factor Receptor (HER) family: structure and function -- 3. Methods for EGFR mutation testing -- 4. Predictive and prognostic implications of EGFR mutations -- 5. EGFR-targeted therapies in non-small cell lung cancer -- 6. Conclusions.
Format
e-Book
Location
Online
Less detail

Head and neck cancer : treatment, rehabilitation, and outcomes

https://libcat.nshealth.ca/en/permalink/provcat34101
[edited by] Elizabeth C. Ward and Corina J. van As-Brooks. (2nd ed.) --San Diego, CA: Plural Publishing , c2014.
Available Online
View e-Book
Location
Online
Head and Neck Cancer: Treatment, Rehabilitation, and Outcomes, Second Edition expands on recent advances in the management of head and neck cancer through a greater understanding of cancer cell growth and mechanisms, as well as the expansion of rehabilitation strategies across the allied health profession. Written by a team of internationally recognized experts from the medical and allied health communities, the book covers both the theoretical and clinical knowledge to support basic training …
Available Online
View e-Book
Other Authors
Ward, Elizabeth C.
As-Brooks, Corina J. van
Responsibility
[edited by] Elizabeth C. Ward and Corina J. van As-Brooks
Edition
2nd ed.
Place of Publication
San Diego, CA
Publisher
Plural Publishing
Date of Publication
c2014
Physical Description
1 online resource (617 p.)
ISBN
9781597566599
Subjects (MeSH)
Deglutition Disorders - rehabilitation
Head and Neck Neoplasms - therapy
Larynx, Artificial
Speech Disorders - rehabilitation
Speech, Alaryngeal
Treatment Outcome
Subjects (LCSH)
Head - Cancer - Treatment
Neck - Cancer - Treatment
Speech disorders - Patients - Rehabilitation
Abstract
Head and Neck Cancer: Treatment, Rehabilitation, and Outcomes, Second Edition expands on recent advances in the management of head and neck cancer through a greater understanding of cancer cell growth and mechanisms, as well as the expansion of rehabilitation strategies across the allied health profession. Written by a team of internationally recognized experts from the medical and allied health communities, the book covers both the theoretical and clinical knowledge to support basic training of therapists in practice as well as graduate students, all illuminated with case examples - from swallowing disorders, through non-surgical voice restoration, to rehabilitation following total laryngeal surgery - on an accompanying DVD. With expanded coverage of current theory and clinical practice, this book continues to be an essential textbook and practical clinical reference for the H&N cancer rehabilitation team.
Format
e-Book
Location
Online
Less detail

Hormone therapy for prostate cancer

https://libcat.nshealth.ca/en/permalink/chpams37500
Nova Scotia Health Authority. GU Cancer Site Team. [Halifax, NS]: Nova Scotia Health Cancer Care Program , 2021.
Pamphlet Number
4010
Available Online
View Pamphlet
The prostate is a gland that makes seminal fluid. Prostate cancer is a disease where cancer cells start to grow in the prostate gland. These cancer cells grow into a tumor and can spread to other parts of the body such as the bones and lymph nodes. This pamphlet explains what causes prostate cancer, what hormones are, what testosterone does, how hormone therapy works for prostate cancer, how long you will be on hormone therapy, and side effects. A list of resources for further information is pr…
Available Online
View Pamphlet
Corporate Author
Nova Scotia Health Authority. GU Cancer Site Team
Place of Publication
[Halifax, NS]
Publisher
Nova Scotia Health Cancer Care Program
Date of Publication
2021
Format
Pamphlet
Language
English
Physical Description
1 electronic document (6 p.) : digital, PDF file
Subjects (MeSH)
Prostatic Neoplasms
Hormones
Subjects (LCSH)
Prostate--Cancer--Treatment
Specialty
Cancer Care
Urogenital System
Abstract
The prostate is a gland that makes seminal fluid. Prostate cancer is a disease where cancer cells start to grow in the prostate gland. These cancer cells grow into a tumor and can spread to other parts of the body such as the bones and lymph nodes. This pamphlet explains what causes prostate cancer, what hormones are, what testosterone does, how hormone therapy works for prostate cancer, how long you will be on hormone therapy, and side effects. A list of resources for further information is provided.
Responsibility
Prepared by: GU Cancer Site Team; Approved by: Nova Scotia Cancer Patient Education Committee
Pamphlet Number
4010
Less detail

Image guided prostate cancer treatments

https://libcat.nshealth.ca/en/permalink/provcat33769
Robert L. Bard, Jurgen J. Fütterer, Dan Sperling, editors. --Heidelberg: Springer , c2014.
Available Online
View e-Book
Location
Online
Image-Guided Prostate Cancer Treatments is a comprehensive reference and practical guide on the technology and application of ultrasound and MRI in the male pelvis, with special attention to the prostate. The book is organized into three main sections, the first of which is devoted to general aspects of imaging and image-guided treatments. The second section provides a systematic overview of the application of ultrasound and MRI to the diagnosis and treatment of diseases of the lower urinary tr…
Available Online
View e-Book
Other Authors
Bard, Robert Laurence
Fütterer, Jurgen J
Sperling, Dan
Responsibility
Robert L. Bard, Jurgen J. Fütterer, Dan Sperling, editors
Place of Publication
Heidelberg
Publisher
Springer
Date of Publication
c2014
Physical Description
1 online resource (xiv, 268 pages)
ISBN
9783642404290 (electronic bk.)
9783642404283
Subjects (MeSH)
Prostatic Neoplasms - diagnosis
Prostatic Neoplasms - therapy
Radiotherapy, Image-Guided
Therapy, Computer-Assisted
Subjects (LCSH)
Prostate - Cancer - Treatment
Prostate - Cancer - Imaging
Image-guided radiation therapy
Prostatic Neoplasms - therapy
Radiotherapy, Image-Guided - therapy
Imaging - Radiology
Ultrasound
Oncology
Abstract
Image-Guided Prostate Cancer Treatments is a comprehensive reference and practical guide on the technology and application of ultrasound and MRI in the male pelvis, with special attention to the prostate. The book is organized into three main sections, the first of which is devoted to general aspects of imaging and image-guided treatments. The second section provides a systematic overview of the application of ultrasound and MRI to the diagnosis and treatment of diseases of the lower urinary tract. Performance of the ultrasound and MRI studies is explained, and the normal and abnormal pathological anatomy is reviewed. Correlation with the ultrasound in the same plane is provided to assist in understanding the MRI sequences. Biopsy and interventional procedures, ultrasound-MRI fusion techniques, and image-guided therapies, including focused ultrasound, photodynamic therapy, microwave and laser ablation, are all fully covered. The third section focuses on securing treatment effectiveness and the use of follow-up imaging to ensure therapeutic success and detect tumor recurrence at an early stage, which is vital given that prompt focal treatment of recurrence is very successful. Here, particular attention is paid to the role of Doppler ultrasound and DCE-MRI technologies. This book, containing a wealth of high-quality illustrations based on high-end equipment, will acquaint beginners with the basics of prostate ultrasound and MRI, while more advanced practitioners will learn new skills, means of avoiding pitfalls, and ways of effectively relating the imaging and image-guided treatments to the clinical situation.
Contents
Part I. Basic Principles -- 1. Current Scope of Prostate Cancer -- 2. Diagnostic Ultrasound Imaging of the Prostate -- 3. Advanced Ultrasound: Prostate Elastography and Photoacoustic Imaging -- 4. Contrast-Enhanced Ultrasound in Prostate Cancer -- 5. Power Doppler Imaging of Prostate Cancer -- 6. Doppler Histogram Vessel Density Analysis -- 7. MR Imaging of the Prostate -- 8. MR Imaging Localization of Prostate Tumors -- 9. Diffusion-Weighted Whole-Body Imaging: Tumor Staging Applications -- 10. MRI-Guided Biopsy -- 11. MRI-Ultrasound Fusion Imaging -- Part II. Clinical Applications -- 12. Clinical Applications of Ultrasound, Doppler Ultrasound, MRI, and DCE-MRI -- 13. Intraprostatic Cancer -- 14. Focal Tumors: Extraprostatic -- 15. Metastatic Disease -- 16. Diagnosing, Treating, and Reversing Prostate Cancers with Hormonal and Nutritional Intervention -- 17. Imaging Detection of Regression and Recurrence -- Part III. Advanced Image Guided Procedures -- 18. Laser Principles -- 19. Focal Laser Ablation of the Prostate -- 20. Focal Therapy for Prostate Cancer Using Irreversible Electroporation -- 21. Photodynamic Therapy -- 22. High-Intensity Focused Ultrasound for the Treatment of Prostate Cancer.
Format
e-Book
Location
Online
Less detail

Implanted vascular access device (IVAD or "port")

https://libcat.nshealth.ca/en/permalink/chpams36613
Nova Scotia Health Authority. QEII. Minor Procedures, Nova Scotia Health Authority. Hants Community Hospital. Same Day Surgery Unit, Nova Scotia Health Authority. Yarmouth Regional Hospital. Oncology Unit. Halifax, NS: Nova Scotia Health Authority , 2019.
Pamphlet Number
0421
Available Online
View Pamphlet
An implanted vascular access device (IVAD) is a small device that goes into a large vein just above your heart. This makes it easier to give you intravenous (IV) medications and to take blood samples. It is also called a “port” or “port-a-cath.” A port is placed under your skin below your collarbone. Topics include: benefits, how it works, how to get ready for surgery, what to expect during and after surgery, care at home, and taking care of your port. A space to write your doctor's name and ph…
Available Online
View Pamphlet
Corporate Author
Nova Scotia Health Authority. QEII. Minor Procedures
Nova Scotia Health Authority. Hants Community Hospital. Same Day Surgery Unit
Nova Scotia Health Authority. Yarmouth Regional Hospital. Oncology Unit
Alternate Title
Port
Port-a-cath
Place of Publication
Halifax, NS
Publisher
Nova Scotia Health Authority
Date of Publication
2019
Format
Pamphlet
Language
English
Physical Description
1 electronic document (5 p.) : digital, PDF file
Subjects (MeSH)
Vascular Access Device
Neoplasms - therapy
Subjects (LCSH)
Drug infusion pumps
Cancer--Treatment
Abstract
An implanted vascular access device (IVAD) is a small device that goes into a large vein just above your heart. This makes it easier to give you intravenous (IV) medications and to take blood samples. It is also called a “port” or “port-a-cath.” A port is placed under your skin below your collarbone. Topics include: benefits, how it works, how to get ready for surgery, what to expect during and after surgery, care at home, and taking care of your port. A space to write your doctor's name and phone number is given in case you have any problems.
Notes
Previous title: Implanted infusion port
Responsibility
Prepared by: Minor Procedures, QEII; SDSU, Hants Community Hospital; Oncology Unit, Yarmouth Regional Hospital
Pamphlet Number
0421
Less detail

Information for patients receiving radiation therapy : breast cancer or ductal carcinoma in situ (DCIS) of the breast

https://libcat.nshealth.ca/en/permalink/chpams37400
Nova Scotia Health Authority. Cancer Care Program. [Halifax, NS]: Nova Scotia Health Cancer Care Program , 2021.
Pamphlet Number
4008
Available Online
View Pamphlet
This pamphlets answers common questions about receiving radiation therapy for breast cancer or Ductal Carcinoma in Situ (DCIS) of the breast. Topics include why radiation therapy is used to treat breast cancer or DCIS, what will happen when you come for your treatment planning, how long it will be until you start your radiation treatments, and how long your treatments will take. Information about side effects and support is also provided. A list of questions you may want to ask your health care…
Available Online
View Pamphlet
Corporate Author
Nova Scotia Health Authority. Cancer Care Program
Place of Publication
[Halifax, NS]
Publisher
Nova Scotia Health Cancer Care Program
Date of Publication
2021
Format
Pamphlet
Language
English
Physical Description
1 electronic document (5 p.) : digital, PDF file
Subjects (MeSH)
Aftercare
Breast Neoplasms - radiotherapy
Self Care
Subjects (LCSH)
Breast--Cancer--Patients--Care
Breast--Cancer--Treatment
Self-care, Health
Specialty
Cancer Care
Abstract
This pamphlets answers common questions about receiving radiation therapy for breast cancer or Ductal Carcinoma in Situ (DCIS) of the breast. Topics include why radiation therapy is used to treat breast cancer or DCIS, what will happen when you come for your treatment planning, how long it will be until you start your radiation treatments, and how long your treatments will take. Information about side effects and support is also provided. A list of questions you may want to ask your health care team is included.
Responsibility
Prepared by: Nova Scotia Health Cancer Care Program; Approved by: Nova Scotia Cancer Patient Education Committee
Pamphlet Number
4008
Less detail

[In French] Forum spécialisé sur les tumeurs aux Services d’oncologie pédiatrique

https://libcat.nshealth.ca/en/permalink/chpams37022
IWK. Hematology / Oncology. Halifax, NS: IWK Health Centre , 2017.
Pamphlet Number
PL-0802-FR
Available Online
View Pamphlet
[In French] Le forum spécialisé sur les tumeurs examine tous les enfants qui reçoivent des soins au IWK et qui reçoivent un nouveau diagnostic de cancer ou qui pourraient recevoir un diagnostic de cancer.
Available Online
View Pamphlet
Corporate Author
IWK. Hematology / Oncology
Alternate Title
IWK Pediatric Oncology Tumour Board
Place of Publication
Halifax, NS
Publisher
IWK Health Centre
Date of Publication
2017
Format
Pamphlet
Language
French
Physical Description
1 electronic document : digital, PDF file
Subjects (MeSH)
Neoplasms - therapy
Patient Care Planning
Subjects (LCSH)
Cancer--Treatment
Medical protocols
Abstract
[In French] Le forum spécialisé sur les tumeurs examine tous les enfants qui reçoivent des soins au IWK et qui reçoivent un nouveau diagnostic de cancer ou qui pourraient recevoir un diagnostic de cancer.
Notes
The English version of this pamphlet PL-0802, "IWK Pediatric Oncology Tumour Board", is also available.
Responsibility
IWK Hematology / Oncology, Halifax, NS
Pamphlet Number
PL-0802-FR
Zone
All Zones
Less detail

IWK Pediatric Oncology Tumour Board

https://libcat.nshealth.ca/en/permalink/chpams37021
IWK. Hematology / Oncology. Halifax, NS: IWK Health Centre , 2017.
Pamphlet Number
PL-0802
Available Online
View Pamphlet
Discusses the purpose of the board, who attends, how the results are conveyed.
Available Online
View Pamphlet
Corporate Author
IWK. Hematology / Oncology
Place of Publication
Halifax, NS
Publisher
IWK Health Centre
Date of Publication
2017
Format
Pamphlet
Language
English
Physical Description
1 electronic document : digital, PDF file
Subjects (MeSH)
Neoplasms - therapy
Patient Care Planning
Subjects (LCSH)
Cancer--Treatment
Medical protocols
Abstract
Discusses the purpose of the board, who attends, how the results are conveyed.
Notes
The French version of this pamphlet PL-0802-FR, "Forum spécialisé sur les tumeurs aux Services d’oncologie pédiatrique", is also available.
Responsibility
IWK Hematology / Oncology, Halifax, NS
Pamphlet Number
PL-0802
Zone
All Zones
Less detail

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