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Acquired Cystic Disease of the Kidney and Renal Cell Carcinoma : Complications of Long-Term Dialysis

https://libcat.nshealth.ca/en/permalink/provcat28396
by Isao Ishikawa. --Tokyo: Springer , c2007.
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Location
Online
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Author
Ishikawa, Isao
Responsibility
by Isao Ishikawa
Place of Publication
Tokyo
Publisher
Springer
Date of Publication
c2007
ISBN
9784431694816
Subjects (MeSH)
Carcinoma, Renal Cell
Kidney Diseases, Cystic
Renal Dialysis - adverse effects
Subjects (LCSH)
Nephrology
Oncology
Format
e-Book
Location
Online
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Clinical Management of Renal Tumors

https://libcat.nshealth.ca/en/permalink/provcat28503
edited by Ronald M. Bukowski, Andrew C. Novick. --Totowa, NJ: Humana Press , c2008.
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Location
Online
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Author
Bukowski, Ronald M
Other Authors
Novick, Andrew C
Responsibility
edited by Ronald M. Bukowski, Andrew C. Novick
Place of Publication
Totowa, NJ
Publisher
Humana Press
Date of Publication
c2008
ISBN
9781603271493
Subjects (MeSH)
Carcinoma, Renal Cell - therapy
Kidney Neoplasms - pathology
Kidney Neoplasms - therapy
Nephrectomy - methods
Subjects (LCSH)
Oncology
Cancer - Surgery
Nephrology
Format
e-Book
Location
Online
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Kidney Cancer : Principles and Practice

https://libcat.nshealth.ca/en/permalink/provcat39301
Primo N. Lara, Eric Jonasch, editors. (Second edition) --Cham: Springer , c2015.
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Location
Online
Kidney Cancer: Principles and Practice is a comprehensive and interdisciplinary textbook that encompasses all clinically relevant aspects of the disease. This new edition has been extensively updated and includes brand new material covering the most recent developments in kidney cancer diagnosis and therapy. The user-friendly and clinically oriented content of the book guarantees that it will be of great interest to a wide range of medical professionals, and every effort has been made to ensure…
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Other Authors
Lara, Primo N
Jonasch, Eric
Responsibility
Primo N. Lara, Eric Jonasch, editors
Edition
Second edition
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2015
Physical Description
1 online resource (x, 402 p. : 63 illus., 48 illus. in color)
ISBN
9783319179032
9783319179025 (print ed.)
Subjects (MeSH)
Carcinoma, Renal Cell - therapy
Abstract
Kidney Cancer: Principles and Practice is a comprehensive and interdisciplinary textbook that encompasses all clinically relevant aspects of the disease. This new edition has been extensively updated and includes brand new material covering the most recent developments in kidney cancer diagnosis and therapy. The user-friendly and clinically oriented content of the book guarantees that it will be of great interest to a wide range of medical professionals, and every effort has been made to ensure that contributions are both easy to understand and directly related to patient care. Content presentation departs from the usual dense chapter format featuring a lengthy series of paragraphs. Instead, each chapter contains several boxed sections, including one that summarizes essential "take home points" for the busy clinician and another that presents a patient-oriented case highlighting the clinical application of elements discussed in that chapter. In addition, accessible original images, illustrations, and diagrams (some in full color) are used to simplify particularly complex material. This book will be of value for clinicians, researchers, residents, fellows, students, and knowledgeable lay people. The contributors comprise an international group of authors with expertise in kidney cancer epidemiology, molecular biology, pathology, diagnosis, clinical features, staging, prognostic and predictive factors, surgery, systemic therapy, and emerging investigational approaches, among others.
Contents
Part I. Epidemiology and Biology -- Epidemiology of Kidney Cancer -- Pathological Classification -- Molecular Biology of Kidney Cancer -- Biomarkers for Kidney Cancer -- Genetic Heterogeneity of Kidney Cancer -- The Metabolic Basis of Kidney Cancer. Part II. Clinical Considerations -- Clinical Presentation and Staging -- Hereditary Kidney Cancer -- Part III. Surgical and Local Control Modalities -- Surgical Approaches to Early Stage Kidney Cancer -- Cytoreductive Nephrectomy -- Metastasectomy -- Energy Ablative Techniques in Kidney Cancer -- The Role of Radiation Therapy in Kidney Cancer -- Part IV. Systemic Therapy Considerations -- Adjuvant Systemic Therapy -- Cytokines and Vaccine Therapy -- PD1 and PDL1 Targeted Therapy -- Angiogenesis Inhibitor Therapy -- The Role of mTOR inhibitors and PI3K Pathway Blockade -- Sequential versus Combination Strategies -- Presurgical Therapy in Kidney Cancer -- Toxicity Management for Patients on Targeted Therapies -- Emerging Agents in Kidney Cancer.
Format
e-Book
Location
Online
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Kidney cancer : principles and practice

https://libcat.nshealth.ca/en/permalink/provcat25492
Lara, Primo N. --Heidelberg, Germany: Springer-Verlag , c2012.
Call Number
WJ 358 K46 2012
Location
Dickson Building
Call Number
WJ 358 K46 2012
Author
Lara, Primo N
Other Authors
Jonasch, Eric
Place of Publication
Heidelberg, Germany
Publisher
Springer-Verlag
Date of Publication
c2012
Physical Description
309 p.
ISBN
9783642218576
Subjects (MeSH)
Carcinoma, Renal Cell
Format
Book
Location
Dickson Building
Loan Period
3 weeks
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Renal Cancer : Contemporary Management

https://libcat.nshealth.ca/en/permalink/provcat40746
John A. Libertino, editor. --New York, NY: Springer , c2013.
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Online
Renal Cancer: Contemporary Management provides a state of the art overview of the major topics in the field of kidney cancer. The material has been collected from the most current evidence based resources to allow for the appropriate care of these patients. The sections of the book have been structured to give an overview of the major issues dealing with renal cell carcinoma and transitional cell carcinoma of the kidney. The text also reviews the new staging system, discusses familial syndromes…
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Other Authors
Libertino, John A
Responsibility
John A. Libertino, editor
Place of Publication
New York, NY
Publisher
Springer
Date of Publication
c2013
Physical Description
1 online resource (ix, 397 p. : 156 illus., 91 illus. in color)
ISBN
9781461472360
9781461472353 (print ed.)
Subjects (MeSH)
Carcinoma, Renal Cell
Kidney Neoplasms
Neoplasm Staging
Abstract
Renal Cancer: Contemporary Management provides a state of the art overview of the major topics in the field of kidney cancer. The material has been collected from the most current evidence based resources to allow for the appropriate care of these patients. The sections of the book have been structured to give an overview of the major issues dealing with renal cell carcinoma and transitional cell carcinoma of the kidney. The text also reviews the new staging system, discusses familial syndromes of renal cell carcinoma, and provides new perspectives with regard to imaging and managing renal tumors. A valuable resource for physicians and researchers dealing with renal cancer, Renal Cancer: Contemporary Management provides a comprehensive summary of the field that will guide patient management and stimulate further clinical and basic science research efforts.
Contents
Epidemiology, Screening and Clinical Staging -- Molecular Biology and Genetics -- Familial and Hereditary Syndromes -- Pathology of Renal Cell Carcinoma -- Imaging of Renal Cancer -- Molecular Imaging for Renal Cell Carcinoma -- History of Renal Surgery for Cancer -- Natural History, Role of Biopsy and Active Surveillance of Renal Masses -- Interventional Radiology and Angioinfarction: Transcatheter Embolization of Renal Tumors -- Unified Approaches to Surgery and Systemic Therapy for Renal Cell Carcinoma -- Rationale for Partial Nephrectomy -- Objectifying Complexity of Kidney Cancers: Relationships of Tumor Anatomy and Outcomes -- Open Partial Nephrectomy -- Minimally Invasive Partial Nephrectomy and Ablative Procedures for Small Renal Masses -- Surgery for Renal Cell Carcinoma with Thrombus Extension into the Vena Cava -- Role of Lymphadenectomy -- Postoperative Surveillance Protocols for Renal Cell Carcinoma -- Role of Surgery in Locally Recurrent and Metastatic Renal Cancer -- Outcomes: Prognostic Factors, Models, and Algorithms -- Adjuvant Systemic Therapy, Immunotherapy and Targeted Treatment -- Role for Radiation Therapy in Renal Cancer -- Surgical Management for Transitional Cell Carcinoma of the Upper Tract -- Management of Non-Clear Cell Renal Cell Carcinoma.
Format
e-Book
Location
Online
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Renal Cancer : Contemporary Management

https://libcat.nshealth.ca/en/permalink/provcat45109
John A. Libertino, Jason R. Gee, editors. (Second edition) --Cham: Springer , c2020.
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Online
This fully updated second edition provides a comprehensive, state-of-the-art review of renal cancer, and will serve as a guide for urology residents, clinicians, surgeons, and researchers with an interest in renal cell carcinoma. The title reviews the latest information regarding epidemiology, clinical staging, molecular biology and genetics, hereditary syndromes, pathology, imaging, molecular imaging, interventional radiology, surgical advances, and the unified approach to surgery and systemic…
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Other Authors
Libertino, John A.
Gee, Jason R.
Responsibility
John A. Libertino, Jason R. Gee, editors
Edition
Second edition
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2020
Physical Description
1 online resource (xxii, 465 p.) : 177 illus., 124 illus. in color
ISBN
9783030243784
9783030243777 (Print ed.)
9783030243791 (Print ed.)
9783030243807 (Print ed.)
Subjects (MeSH)
Carcinoma, Renal Cell
Kidney Neoplasms
Neoplasm Staging
Specialty
Medical Oncology
Nephrology
Abstract
This fully updated second edition provides a comprehensive, state-of-the-art review of renal cancer, and will serve as a guide for urology residents, clinicians, surgeons, and researchers with an interest in renal cell carcinoma. The title reviews the latest information regarding epidemiology, clinical staging, molecular biology and genetics, hereditary syndromes, pathology, imaging, molecular imaging, interventional radiology, surgical advances, and the unified approach to surgery and systemic therapy of renal cell carcinoma. It also addresses the management of localized RCC, locally advanced disease, and advanced disease. A valuable resource for physicians and researchers dealing with renal cancer, Renal Cancer: Contemporary Management, Second Edition provides a comprehensive summary of the field that will guide patient management and stimulate further clinical and basic science research efforts.
Contents
Epidemiology, Screening, and Clinical Staging -- Molecular Biology and Genetics -- Familial and Hereditary Syndromes in Renal Cell Carcinoma -- Pathology of Renal Cell Cancer -- Imaging of Renal Cell Cancer -- Molecular Imaging for Renal Cell Carcinoma -- Interventional Radiology and Angioinfarction: Embolization of Renal Tumors -- Natural History, Role of Biopsy, and Active Surveillance of Renal Masses -- Rational for Partial Nephrectomy: Current Practice Patterns -- Objectifying Complexity of Kidney Cancer: Relationship of Tumor Anatomy and Outcomes -- History of Renal Surgery for Cancer -- The Surgical Approaches to Renal Masses and their Impact on Post-operative Renal Function -- Open Partial Nephrectomy -- Minimally Invasive Partial Nephrectomy and Ablative Procedures for Small Renal Masses -- Surgery for Renal Cell Carcinoma with Thrombus Extension into the Vena Cava -- Role of Lymphadenectomy in Renal Cell Cancer -- Role of Surgery in Locally Recurrent and Metastatic Renal Cancer -- Management of Non-Clear Renal Cell Carcinoma -- Surgical Management for Transitional Carcinoma of the Upper Tract -- Outcomes: Prognostic Factors, Models, and Algorithms -- Postoperative Surveillance Protocols for Renal Cell Carcinoma -- Role of Radiation Therapy in Renal Cancer -- Adjuvant Systemic Therapy, Immunotherapy and Targeted Treatment -- Unified Approached to Surgery and Systemic Therapy for Renal Cell Carcinoma -- Defining an Individualized Treatment Strategy for Metastatic Renal Cancer.
Format
e-Book
Location
Online
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Renal Cell Cancer : Diagnosis and Therapy

https://libcat.nshealth.ca/en/permalink/provcat28321
edited by Jean J.M.C.H. de la Rosette, Cora N. Sternberg, Hein P.A. van Poppel. --London: Springer-Verlag , c2008.
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Location
Online
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Author
Rosette, Jean J.M.C.H. de la
Other Authors
Sternberg, Cora N
Poppel, Hein P.A. van
Responsibility
edited by Jean J.M.C.H. de la Rosette, Cora N. Sternberg, Hein P.A. van Poppel
Place of Publication
London
Publisher
Springer-Verlag
Date of Publication
c2008
ISBN
9781846287633
Subjects (MeSH)
Carcinoma, Renal Cell - diagnosis
Carcinoma, Renal Cell - therapy
Subjects (LCSH)
Oncology
Nephrology
Format
e-Book
Location
Online
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Renal cell carcinoma : clinical management

https://libcat.nshealth.ca/en/permalink/provcat32451
Steven C. Campbell, Brian I. Rini, editors. --New York, NY: Humana Press , c2013.
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Location
Online
Renal Cell Carcinoma: Clinical Management provides a comprehensive, state-of-the art review of this field, and will serve as a valuable resource for clinicians, surgeons and researchers with an interest in kidney cancer. The volume reviews new data about risk factors for the disease, profiles the new staging system for renal cell carcinoma (RCC), highlights our current understanding of familial syndromes of RCC and their molecular genetics, and provides new perspectives about imaging of renal t…
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Other Authors
Campbell, Steven C
Rini, Brian I
Responsibility
Steven C. Campbell, Brian I. Rini, editors
Place of Publication
New York, NY
Publisher
Humana Press
Date of Publication
c2013
Physical Description
1 online resource (xi, 362 p. : 91 ill., 46 ill. in color)
Series Title
Current clinical urology
ISBN
9781627030625
Subjects (MeSH)
Carcinoma, Renal Cell - therapy
Subjects (LCSH)
Oncology
Urology
Abstract
Renal Cell Carcinoma: Clinical Management provides a comprehensive, state-of-the art review of this field, and will serve as a valuable resource for clinicians, surgeons and researchers with an interest in kidney cancer. The volume reviews new data about risk factors for the disease, profiles the new staging system for renal cell carcinoma (RCC), highlights our current understanding of familial syndromes of RCC and their molecular genetics, and provides new perspectives about imaging of renal tumors. For localized disease, a greater appreciation of nephron-sparing approaches and the importance of preservation of renal function is discussed in detail. Advances in surgical techniques are highlighted. For metastatic disease, the molecular biology of kidney cancer is reviewed in a concise and understandable manner, including the data that has fostered novel targeted approaches that have revolutionized management. The several landmark phase III targeted therapy trials published in the last few years are placed in context with respect to current management.
Contents
Section I: Localized Disease -- 1.Etiology of RCC: Incidence, Demographics, and Environmental Factors -- 2.Pathology of Renal Cell Carcinoma -- 3.Familial Renal Cell Carinoma -- 4.Imaging of Renal Cell Carcinoma -- 5.Prognostic Factors for Localized Renal Cell Carcinoma -- Section II: Management of Localized RCC -- 6.Assessment of Oncologic Risk for Clinical Stage T1 Renal Tumors and the Emerging Role of Renal Mass Biopsy -- 7.Radical Nephrectomy for Localized Renal Tumors: Oncological and Renal Functional Considerations -- 8.Nephron-Sparing Surgery for Renal Cancer -- 9.Thermal Ablation -- 10.Active Surveillance of the Small Renal Mass -- Section III: Locally Advanced Disease -- 11.Locally Advanced Renal Cell Carcinoma -- 12.Neoadjuvant Targeted Therapy and Consolidative Surgery -- Section IV: Advanced Disease -- 13.Biology of RCC (VEGF, mTOR, immune aspects) -- 14.Prognostic Factors in Advanced Renal Cell Carcinoma -- 5.Integration of Surgery in Metastatic Renal Cancer -- 16.Immunotherapy for Renal Cell Carcinoma -- 17.Targeted Therapy: Vascular Endothelial Growth Factor (VEGF) -- 18.mTOR in Renal cell carcinoma -- 19.Palliative and Supportive Care for Renal Cancer.
Format
e-Book
Location
Online
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Renal Cell Carcinoma : Molecular Features and Treatment Updates

https://libcat.nshealth.ca/en/permalink/provcat41913
Mototsugu Oya, editor. --Tokyo: Springer , 2017.
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Online
This book provides a comprehensive review of diagnosis and treatments of renal cell carcinoma (RCC) for practitioners and researchers with an interest in this disease. A major aim of the book is to present the most important and most recent advances in molecular bases and targeted therapy for this neoplasm. The remarkable resistance to chemotherapy and radiotherapy and the minimum contribution of cancer genes that commonly mutate in other adult epithelial cancers have made RCC highly distinct f…
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Other Authors
Oya, Mototsugu
Responsibility
Mototsugu Oya, editor
Place of Publication
Tokyo
Publisher
Springer
Date of Publication
2017
Physical Description
1 online resource (x, 381 pages) : 78 illus., 54 illus. in color
ISBN
9784431555315
9784431555308 (print ed.)
Subjects (MeSH)
Carcinoma, Renal Cell - diagnosis
Carcinoma, Renal Cell - drug therapy
Carcinoma, Renal Cell - surgery
Molecular Targeted Therapy
Abstract
This book provides a comprehensive review of diagnosis and treatments of renal cell carcinoma (RCC) for practitioners and researchers with an interest in this disease. A major aim of the book is to present the most important and most recent advances in molecular bases and targeted therapy for this neoplasm. The remarkable resistance to chemotherapy and radiotherapy and the minimum contribution of cancer genes that commonly mutate in other adult epithelial cancers have made RCC highly distinct from other types of solid neoplasms. In the past decade, however, treatment options for RCC have been expanding and moving quickly toward laboratory-based and molecular-targeted therapies. Advances in RCC therapy also have brought novel treatment options to other types of cancer, such as a TKI for hepatocellular carcinoma and gastrointestinal tumors, as well as mTOR inhibitors to progressive neuroendocrine tumors of pancreatic origin and to breast cancer, suggesting that RCC is no longer an "orphan disease" in the field of molecular oncology. Additional topics covered in the book include pharmacokinetics and pharmacodynamics in molecular-targeted agents and the putative mechanism of resistance to anti-angiogenic agents, such as intratumoral heterogeneity or cancer stem cell population. This volume provides the latest and most useful information for all readers who are eagerly devoted to curing renal cell carcinoma.
Contents
Chapter 1. Epidemiology of Renal Cell Carcinoma -- Chapter 2. Hereditary Renal Cell Carcinoma -- Chapter 3. Molecular Genetics of Renal Cell Carcinoma -- Chapter 4. Pathology of Renal Cell Carcinoma -- Chapter 5. Imaging Features of Renal Cell Carcinoma: Differential Diagnosis, Staging and Post-Treatment Evaluation -- Chapter 6. Treatment Overview -- Chapter 7. Natural History and Active Surveillance -- Chapter 8. Surgical Treatment for Renal Cell Carcinoma -- Chapter 9. Predictive and Prognostic Markers in Metastatic Renal Cell Carcinoma -- Chapter 10 Tyrosine-Kinase Inhibitors: Sorafenib, Sunitinib, Axitinib, Pazopanib -- Chapter 11. Mammalian Targets of Rapamycin Inhibitors: Temsirolimus, Everolimus -- Chapter 12. Immunotherapy for Renal Cell Carcinoma (RCC): Including Immune Checkpoint Blockade Therapy -- Chapter 13. Treatment for Non-Clear Cell Renal Cell Carcinoma -- Chapter 14. Forthcoming Drugs for Metastatic Renal Cell Carcinoma Therapy -- Chapter 15. Refractory Mechanisms -- Chapter 16. Optimization of Therapy by Pharmacokinetic: Pharmacodynamic Analyses.
Format
e-Book
Location
Online
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Renal Cell Carcinoma : Molecular Targets and Clinical Applications

https://libcat.nshealth.ca/en/permalink/provcat38966
Ronald M. Bukowski, Robert A. Figlin, Robert J. Motzer, editors. (3rd ed.) --New York, NY: Springer , c2015.
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Online
The third edition of this critically acclaimed book has updated and expanded the survey of clinical, biological and pathological management of localized and advanced renal cell carcinoma. Internationally renowned editors and contributors explore the latest developments in molecular genetics, focusing on the novel targets that have been discovered in epithelial renal tumors. Comprehensive and authoritative, Renal Cell Carcinoma: Molecular Targets and Clinical Applications, Third Edition is the d…
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Other Authors
Bukowski, Ronald M
Figlin, Robert A
Motzer, Robert J
Responsibility
Ronald M. Bukowski, Robert A. Figlin, Robert J. Motzer, editors
Edition
3rd ed.
Place of Publication
New York, NY
Publisher
Springer
Date of Publication
c2015
Physical Description
1 online resource (xviii, 613 p. : 50 illus., 41 illus. in color)
ISBN
9781493916221
9781493916214 (print ed.)
Subjects (MeSH)
Carcinoma, Renal Cell
Kidney Neoplasms
Abstract
The third edition of this critically acclaimed book has updated and expanded the survey of clinical, biological and pathological management of localized and advanced renal cell carcinoma. Internationally renowned editors and contributors explore the latest developments in molecular genetics, focusing on the novel targets that have been discovered in epithelial renal tumors. Comprehensive and authoritative, Renal Cell Carcinoma: Molecular Targets and Clinical Applications, Third Edition is the definitive text on the rapidly evolving landscape of experimental therapeutics, written and edited by leaders of the field.
Contents
1 Targeted Therapy for Metastatic Renal Cell Carcinoma: Introduction -- 2 Renal Cell Carcinoma: Pathologic and Molecular Assessment of Targets -- 3 Genomic Assessment of Renal Cancer -- 4 VHL and HIF in Clear Cell Renal Cell Carcinoma: Molecular Abnormalities and Potential Clinical Applications -- 5 PBRM1: A Critical Subunit of the SWI/SNF Chromatin Remodeling Complex -- 6 Sporadic RCC: Abnormalities in Histone- Modifying Genes -- 7 Genetic Heterogeneity in Renal Cell Carcinoma: Clinical Implications? -- 8 First-Generation Tyrosine Kinase Inhibitors: Clinical Results -- 9 Second-Generation Tyrosine Kinase Inhibitors (Pazopanib) in Renal Cell Carcinoma: Current Status -- 10 Third-Generation TKIs (Axitinib, Tivozanib) in RCC: Enhanced Efficacy and Diminished Toxicity? -- 11 Anti-VEGF and VEGFR Monoclonal Antibodies in RCC -- 12 PI3-kinase, Akt, and mTOR Inhibitors in RCC -- 13 Carbonic Anhydrase IX and Monoclonal Antibody G250: Relevance as a Clinical and Biologic Target in Renal Cell Carcinoma -- 14 EGFR and HER2: Relevance in Renal Cell Carcinoma -- 15 The Role of Hepatocyte Growth Factor Pathway Signaling in Renal Cell Carcinoma -- 16 Development of Resistance to Targeted Therapy: Preclinical Findings and Clinical Relevance -- 17 Development of Combination Therapy with Targeted Agents -- 18 Side Effects of Targeted Therapy -- 19 The Role of Targeted Therapy in Special Populations -- 20 Immunotherapy: The Current Role of Cytokines -- 21 Immune Checkpoint Inhibitors (Anti-CTLA4, Anti-PD-1) in RCC -- 22 Vaccines in RCC: Clinical and Biological Relevance -- 23 Development and Incorporation of Biomarkers in RCC Therapeutics -- 24 Molecularly Targeted Staging Strategies in Renal Cell Carcinoma -- 25 Clinical Prognostic Factors in Metastatic Renal Cell Carcinoma -- 26 The Role of Advocacy in Renal Cell Carcinoma.
Format
e-Book
Location
Online
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