Aging and the heart : A Post-Genomic View
https://libcat.nshealth.ca/en/permalink/provcat28046
by José Marín-García, Michael J. Goldenthal, Gordon W. Moe.
--Boston, MA:
Springer Science+Business Media
, c2008.
- Available Online
- View e-Book
- Location
- Online
- Available Online
- View e-Book
- Author
- Marín-García, José
- Other Authors
- Goldenthal, Michael J
- Moe, Gordon W
- Responsibility
- by José Marín-García, Michael J. Goldenthal, Gordon W. Moe
- Place of Publication
- Boston, MA
- Publisher
- Springer Science+Business Media
- Date of Publication
- c2008
- ISBN
- 9780387740720
- Subjects (MeSH)
- Aging - physiology
- Cardiovascular Diseases - genetics
- Cardiovascular Diseases - physiopathology
- Subjects (LCSH)
- Cardiology
- Geriatrics
- Format
- e-Book
- Location
- Online
Cardiovascular Disease in Racial and Ethnic Minorities
https://libcat.nshealth.ca/en/permalink/provcat29594
edited by Keith C. Ferdinand, Annemarie Armani.
--Totowa, NJ:
Humana Press
, c2010.
- Available Online
- View e-Book
- Location
- Online
- Available Online
- View e-Book
- Author
- Ferdinand, Keith C
- Other Authors
- Armani, Annemarie
- Responsibility
- edited by Keith C. Ferdinand, Annemarie Armani
- Place of Publication
- Totowa, NJ
- Publisher
- Humana Press
- Date of Publication
- c2010
- Series Title
- Contemporary cardiology (Totowa, N.J. : Unnumbered)
- ISBN
- 9781597454100
- Subjects (MeSH)
- Cardiovascular Diseases - genetics
- Minority Groups
- Ethnic Groups
- Healthcare Disparities
- Minority Health
- Format
- e-Book
- Location
- Online
Cardiovascular Genetics and Genomics : Principles and Clinical Practice
https://libcat.nshealth.ca/en/permalink/provcat42927
edited by Dhavendra Kumar, Perry Elliott.
--Cham:
Springer
, c2018.
- Available Online
- View e-Book
- Location
- Online
This title reflects the exponential growth in the knowledge and information on this subject and defines the extensive clinical translation of cardiovascular genetics and genomics in clinical practice. This concise, clinically oriented text is targeted at a broad range of clinicians who manage patients and families with a wide range of heterogeneous inherited cardiovascular conditions. Cardiovascular Genetics and Genomics: Principles and Clinical Practiceáincludes a concise and clear account on …
- Available Online
- View e-Book
- Other Authors
- Kumar, Dhavendra
- Elliott, Perry
- Responsibility
- edited by Dhavendra Kumar, Perry Elliott
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2018
- Physical Description
- 1 online resource (xix, 920 p.) : 164 illus., 110 illus. in color
- ISBN
- 9783319661148
- 9783319661124 (print ed.)
- 9783319661131 (print ed.)
- 9783319881799 (print ed.)
- Subjects (MeSH)
- Cardiovascular Diseases - genetics
- Genomics - methods
- Specialty
- Cardiology
- Genetics, Medical
- Abstract
- This title reflects the exponential growth in the knowledge and information on this subject and defines the extensive clinical translation of cardiovascular genetics and genomics in clinical practice. This concise, clinically oriented text is targeted at a broad range of clinicians who manage patients and families with a wide range of heterogeneous inherited cardiovascular conditions. Cardiovascular Genetics and Genomics: Principles and Clinical Practiceáincludes a concise and clear account on selected topics written by a team of leading experts on clinical cardiovascular genetics. Each chapter include key information to assist the clinician and case histories have been incorporated to reflect contemporary practice in clinical cardiovascular genetics and genomics. Therefore this will be of key importance to all professionals working in the discipline, from clinicians and trainees in cardiology, cardiac surgery, electrophysiology, immunology through geneticists, nursing staff and those involved in precision medicine.
- Contents
- Introduction to Genes, Genome and Inheritance -- Elements of Clinical Cardiovascular Genetics: Spectrum and Classification -- Principles and Practice of Genetic Counselling for Inherited Cardiac Conditions -- Genetic and Genomic Technologies: Next Generation Sequencing for Inherited Cardiovascular Conditions -- Pharmacogenetics and pharmacogenomics in cardiovascular medicine and surgery -- Congenital Cardiovascular Disorders including Adult Congenital Heart Disease -- Inherited cardiovascular metabolic disorders -- Mitochondrial cardiovascular diseases -- Inherited Cardiac Muscle Disorders: Hypertrophic and Restrictive Cardiomyopathies -- Inherited Cardiac Muscle Disorders: Dilated Cardiomyopathy -- Inherited Cardiac Muscle Disorders: Arrhythmogenic Right Ventricular Cardiomyopathy -- Inherited Cardiac Muscle Disorders: Left Ventricular Noncompaction -- Inherited arrhythmias: LQTS/SQTS/CPVT -- Inherited arrhythmias: Brugada syndrome and early repolarisation syndrome -- Inherited Conduction Disease and Atrial Fibrillation -- Cardiovascular manifestations in Duchenne/Becker muscular dystrophy and other primary myopathies -- Inherited cardiac amyloidosis -- Cardiovascular manifestations of inherited myotonias -- Marfan syndrome and related inherited aortopathies -- Cardiovascular manifestations in inherited connective tissue disorders -- Thoracic aortic dilatation, aneurysm and dissection -- Genetics and genomics of coronary artery disease -- Cardiovascular manifestations of immune-mediated inflammatory Disorders -- Genetics and Genomics of Stroke -- Genetics and genomics of systemic hypertension -- Inherited pulmonary arterial hypertension -- Genetics and Genomics of Sudden Unexplained Cardiac Death -- Specific issues in clinical genetics and genetic counselling practices related to inherited cardiovascular conditions -- Multidisciplinary management for inherited cardiovascular conditions -- Internal devices and interventions for inherited cardiac conditions -- Inherited cardiovascular conditions: phenotype-genotype data mining and sharing; databases.
- Format
- e-Book
- Location
- Online
Cardiovascular Genomics
https://libcat.nshealth.ca/en/permalink/provcat30154
edited by Mohan K. Rai, Julian F. R. Paton, Sergey Kasparov, Michael J. Katovich.
--Totowa, NJ:
Humana Press
, c2005.
- Available Online
- View e-Book
- Location
- Online
- Available Online
- View e-Book
- Author
- Rai, Mohan K
- Other Authors
- Paton, Julian F. R
- Kasparov, Sergey
- Katovich, Michael J
- Responsibility
- edited by Mohan K. Rai, Julian F. R. Paton, Sergey Kasparov, Michael J. Katovich
- Place of Publication
- Totowa, NJ
- Publisher
- Humana Press
- Date of Publication
- c2005
- Series Title
- Contemporary cardiology (Totowa, N.J. : Unnumbered)
- ISBN
- 9781592598830
- Subjects (LCSH)
- Cardiology
- Genetics
- Format
- e-Book
- Location
- Online
Cellular and molecular pathobiology of cardiovascular disease
https://libcat.nshealth.ca/en/permalink/provcat33110
edited by Monte S. Willis, Jonathon W. Homeister, James R. Stone.
--London, UK:
Elsevier / AP
, c2014.
- Available Online
- View e-Book
- Access
- Registration required for PDF access.
- Location
- Online
Focuses on the pathophysiology of common cardiovascular disease in the context of its underlying mechanisms and molecular biology. This book has been developed from the editors' experiences teaching an advanced cardiovascular pathology course for PhD trainees in the biomedical sciences, and trainees in cardiology, pathology, public health, and veterinary medicine.
- Available Online
- View e-Book
- Other Authors
- Willis, Monte S
- Homeister, Jonathon W
- Stone, James R
- Responsibility
- edited by Monte S. Willis, Jonathon W. Homeister, James R. Stone
- Place of Publication
- London, UK
- Publisher
- Elsevier / AP
- Date of Publication
- c2014
- Physical Description
- 1 online resource (xvii, 320 pages)
- ISBN
- 9780124055254 (e-Book)
- Subjects (LCSH)
- Cardiovascular system - Diseases - Molecular aspects
- Cardiovascular toxicology
- Cardiovascular Diseases - genetics
- Cardiovascular Diseases - physiopathology
- Cardiovascular diseases - Chemically induced
- Abstract
- Focuses on the pathophysiology of common cardiovascular disease in the context of its underlying mechanisms and molecular biology. This book has been developed from the editors' experiences teaching an advanced cardiovascular pathology course for PhD trainees in the biomedical sciences, and trainees in cardiology, pathology, public health, and veterinary medicine.
- Access
- Registration required for PDF access.
- Format
- e-Book
- Location
- Online
Cellular and molecular pathobiology of cardiovascular disease
https://libcat.nshealth.ca/en/permalink/provcat50477
Willis, Monte.
(1st ed.)
--Philadelphia, PA:
Elsevier
, 2014.
- Available Online
- View e-Book
- Location
- Online
- Available Online
- View e-Book
- Author
- Willis, Monte
- Edition
- 1st ed.
- Place of Publication
- Philadelphia, PA
- Publisher
- Elsevier
- Date of Publication
- 2014
- ISBN
- 9780124052062
- Notes
- Access to this online resource is restricted to IWK Health Centre employees working from inside the hospital network.
- Format
- e-Book
- Location
- Online
Clinical Cardiogenetics
https://libcat.nshealth.ca/en/permalink/provcat40329
Hubert F. Baars, Pieter A. F. M. Doevendans, Arjan C. Houweling, J. Peter van Tintelen, editors.
(2nd ed.)
--Cham:
Springer
, c2016.
- Available Online
- View e-Book
- Location
- Online
This extensively revised second edition provides a thorough basic knowledge on the genetic aspects of cardiovascular disorders. Many cardiologists have not been specifically trained in genetics, let alone in explaining genetics to their patients. While clinics for cardiogenetic disorders have been established in many academic teaching hospitals, it is neither desirable nor feasible that the care for this large group of patients and their relatives remains solely restricted to this small number …
- Available Online
- View e-Book
- Responsibility
- Hubert F. Baars, Pieter A. F. M. Doevendans, Arjan C. Houweling, J. Peter van Tintelen, editors
- Edition
- 2nd ed.
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2016
- Physical Description
- 1 online resource (viii, 405 p. : 93 illus., 55 illus. in color)
- ISBN
- 9783319442037
- 9783319442020 (print ed.)
- Subjects (MeSH)
- Cardiovascular Diseases - genetics
- Genetic predisposition to disease
- Abstract
- This extensively revised second edition provides a thorough basic knowledge on the genetic aspects of cardiovascular disorders. Many cardiologists have not been specifically trained in genetics, let alone in explaining genetics to their patients. While clinics for cardiogenetic disorders have been established in many academic teaching hospitals, it is neither desirable nor feasible that the care for this large group of patients and their relatives remains solely restricted to this small number of centers. This book reviews the expertise that all cardiologists, clinical and molecular geneticists, genetic nurses, and social workers need to provide optimal care for individuals with cardiac disease of probable genetic origin and their family members. Clinical Cardiogenetics, Second Edition, compiles the huge amount of information available in a single easy-to-read textbook. It does not require prior expert genetic knowledge and provides a practical clinical primer for cardiologists and other physicians involved in the management of these patients. With the continuing increase in genetic knowledge, and the expanding possibilities to prevent fatal arrhythmias in those individuals at high risk, a steady increase in questions regarding genetics from patients and their relatives in the years to come should be expected. This comprehensive textbook is a valuable tool in dealing with such questions.
- Contents
- Part I: Genetics -- 1 Introduction to Molecular Genetics -- 2 Clinical Genetics -- Part II: Cardiomyopathies -- 3 Introduction Hereditary Cardiomyopathies -- 4 Hypertrophic Cardiomyopathy -- 5 Dilated Cardiomyopathy -- 6 Arrhythmogenic Cardiomyopathy -- 7 Left Ventricular Noncompaction -- 8 Restrictive Cardiomyopathy -- 9 Mitochondrial Cardiomyopathy -- Part III: Hereditary Arrhythmia Syndromes -- 10 Long QT Syndrome -- 11 Brugada Syndrome -- 12 Catecholaminergic Polymorphic Ventricular Tachycardia -- 13 Short QT Syndrome -- 14 Idiopathic Ventricular Fibrillation -- 15 A Molecular Genetic Perspective on Atrial Fibrillation -- 16 Hereditary Cardiac Conduction Diseases -- Part IV: Hereditary Aortic Diseases -- 17 Heritable Thoracic Aortic Disorders -- 18 Bicuspid Aortic Valve -- Part V: Sudden Cardiac Death in the Young -- 19 Sudden Cardiac Death in the Young; Epidemiology and Cardiogenetic Evaluation of Victims and Their Relatives -- Part VI: Miscellaneous -- 20 The Genetics of Mitral Valve Prolapse -- 21 Genetic Disorders of Lipoprotein Metabolism: Diagnosis and Management -- 22 Genetics of (Premature) Coronary Artery Disease -- 23 Hereditary Neuromuscular Diseases and Cardiac Involvement -- 24 Future of Cardiogenetics -- Index.
- Format
- e-Book
- Location
- Online
Clinical Cardiogenetics
https://libcat.nshealth.ca/en/permalink/provcat45501
Hubert F. Baars, Pieter A. F. M. Doevendans, Arjan C. Houweling, J. Peter van Tintelen, editors.
(Third edition)
--Cham:
Springer
, c2020.
- Available Online
- View e-Book
- Location
- Online
This thoroughly revised third edition provides a comprehensive grounding on hereditary heart diseases with special emphasis on the genetic aspects of these conditions. It continues to provide the expertise that all cardiologists, clinical and molecular geneticists, and related medical professionals require to provide optimal care for patients with cardiac disease of genetic origin and for their relatives. Topics covered include the different cardiomyopathies, the primary arrhythmia syndromes an…
- Available Online
- View e-Book
- Responsibility
- Hubert F. Baars, Pieter A. F. M. Doevendans, Arjan C. Houweling, J. Peter van Tintelen, editors
- Edition
- Third edition
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2020
- Physical Description
- 1 online resource (xiii, 461 p.) : 131 illus., 122 illus. in color
- ISBN
- 9783030454579
- 9783030454562 (Print ed.)
- 9783030454586 (Print ed.)
- 9783030454593 (Print ed.)
- Subjects (MeSH)
- Cardiovascular Diseases - genetics
- Genetic Predisposition to Disease
- Heart Defects, Congenital
- Specialty
- Cardiology
- Genetics, Medical
- Abstract
- This thoroughly revised third edition provides a comprehensive grounding on hereditary heart diseases with special emphasis on the genetic aspects of these conditions. It continues to provide the expertise that all cardiologists, clinical and molecular geneticists, and related medical professionals require to provide optimal care for patients with cardiac disease of genetic origin and for their relatives. Topics covered include the different cardiomyopathies, the primary arrhythmia syndromes and the hereditary thoracic aortic disorders. In addition other topics such as cardiac involvement in hereditary neuromuscular diseases, the clinical policy for sudden cardiac death and the possibilities of pre-implantation genetic diagnosis are included to extend the discussion. Clinical Cardiogenetics compiles current knowledge on the topic in an easy to understand reference. It provides a practical clinical primer for cardiologists, clinical geneticists, trainees and other physicians involved in the management of these patients.
- Contents
- Part I. Genetics -- 1. Introduction to Molecular Genetics -- 2. Clinical Genetics -- Part II. Cardiomyopathies -- 3. Introduction to Hereditary Cardiomyopathies -- 4. Hypertrophic Cardiomyopathy -- 5. Dilated Cardiomyopathy -- 6. Arrhythmogenic Cardiomyopathy -- 7. Left Ventricular Noncompaction -- 8. Restrictive Cardiomyopathy -- 9. Metabolic Cardiomyopathy -- 10. Cardiac Amyloidosis -- 11. Mitochondrial Cardiomyopathies -- Part III. Inherited Arrhythmia Syndromes -- 12. Long QT Syndrome -- 13. Short QT Syndrome -- 14. Brugada Syndrome -- 15. Catecholaminergic Polymorphic Ventricular -- 16. Idiopathic Ventricular Fibrillation and Early Repolarization Syndrome -- 17. Hereditary Cardiac Conduction Diseases -- 18. A Molecular Genetic Perspective on Atrial Fibrillation -- Part IV. Hereditary Thoracic Aortic Diseases -- 19. Heritable Thoracic Aortic Diseases: Syndromal and Isolated (F)TAAD -- 20. Bicuspid Aortic Valve -- Part V. Miscellaneous -- 21. Sudden Cardiac Death in the Young: Post-mortem Investigation and Cardiogenetic Evaluation of Victims and Their Relatives -- 22. Hereditary Neuromuscular Diseases and Cardiac Involvement -- 23. Genetic Disorders of Lipoprotein Metabolism: Diagnosis and Management -- 24. Genetics of (Premature) Coronary Artery Disease -- 25. The Genetics of Mitral Valve Prolapse -- 26. Induced Pluripotent Stem Cells -- 27. Prenatal Diagnosis and Preimplantation Genetic Testing for Inherited Cardiac Diseases.
- Format
- e-Book
- Location
- Online
Genes and Cardiovascular Function
https://libcat.nshealth.ca/en/permalink/provcat28118
edited by Bohuslav Ostadal, Makoto Nagano, Naranjan S. Dhalla.
--Boston, MA:
Springer Science+Business Media
, c2011.
- Available Online
- View e-Book
- Location
- Online
- Available Online
- View e-Book
- Author
- Ostadal, Bohuslav
- Other Authors
- Nagano, Makoto
- Dhalla, Naranjan S
- Responsibility
- edited by Bohuslav Ostadal, Makoto Nagano, Naranjan S. Dhalla
- Place of Publication
- Boston, MA
- Publisher
- Springer Science+Business Media
- Date of Publication
- c2011
- ISBN
- 9781441972071
- Subjects (MeSH)
- Cardiovascular Diseases - genetics
- Subjects (LCSH)
- Cardiology
- Genetics
- Format
- e-Book
- Location
- Online
Genetic cardiomyopathies : a clinical approach
https://libcat.nshealth.ca/en/permalink/provcat32532
Gianfranco Sinagra, Luisa Mestroni, Fulvio Camerini, editors ; foreword by Perry Elliott.
--Milan:
Springer
, c2013.
- Available Online
- View e-Book
- Location
- Online
In the last decade, genetics has been emerging as a primary issue in the diagnosis and management of cardiomyopathies. This book is intended to be a state-of-the-art monograph on these diseases, describing their genetic causes, defining the molecular basis and presenting extensive descriptions of genotypeÇôphenotype correlations. Other chapters are focused on the role of clinical observation, on ECG and echocardiography. With its highlight on the most recent discoveries in the field of molecul…
- Available Online
- View e-Book
- Other Authors
- Sinagra, Gianfranco
- Mestroni, Luisa
- Camerini, Fulvio
- Responsibility
- Gianfranco Sinagra, Luisa Mestroni, Fulvio Camerini, editors ; foreword by Perry Elliott
- Place of Publication
- Milan
- Publisher
- Springer
- Date of Publication
- c2013
- Physical Description
- 1 online resource (xi, 166 p.)
- ISBN
- 9788847027572
- Subjects (MeSH)
- Cardiomyopathies - genetics
- Cardiovascular Diseases - genetics
- Genetic predisposition to disease
- Subjects (LCSH)
- Cardiology
- Abstract
- In the last decade, genetics has been emerging as a primary issue in the diagnosis and management of cardiomyopathies. This book is intended to be a state-of-the-art monograph on these diseases, describing their genetic causes, defining the molecular basis and presenting extensive descriptions of genotypeÇôphenotype correlations. Other chapters are focused on the role of clinical observation, on ECG and echocardiography. With its highlight on the most recent discoveries in the field of molecular genetics as well as on the correct clinical approach to patients with heart muscle disease, the book is aimed at physicians and clinical cardiologists with a particular interest in myocardial diseases and in their genetic causes.
- Contents
- 1 Introduction -- 2 Family History -- 3 The Role of Clinical Observation: Red Flag 1 - Cardiomyopathies and Skeletal Muscle Involvement -- 4 The Role of Clinical Observation: Red Flag 2 - Cardiomyopathies and Arrhythmias -- 5 The Role of Clinical Observation: Red Flag 3 - Cardiomyopathies, WPW Syndrome and Other ECG Abnormalities -- 6 The Role of Clinical Observation: Red Flag 4 - Cardiomyopathies and Sensorineural Hearing Loss -- 7 The Role of Clinical Observation: Red Flag 5 - Right Ventricular Involvement, Arrhythmogenic Right Ventricular Cardiomyopathy and Associated Phenotypes -- 8 The Role of Clinical Observation: Red Flag 6 - Left Ventricular Non-Compaction -- 9 The Role of Clinical Observation: Red Flag 7 - Syndromic and Multisystem Cardiomyopathies -- 10 The Role of Clinical Observation: Red Flag 8 -á Cardiomyopathies in the First Year of Life and Paediatric Cardiomyopathies -- 11 Clinical Genetic Testing in Cardiomyopathies -- 12 Conclusive Remarks.
- Format
- e-Book
- Location
- Online
Post-genomic cardiology
https://libcat.nshealth.ca/en/permalink/provcat27609
Marin-Garcia, Jose.
--Amsterdam, Netherlands:
Elsevier Academic Press
, 2007.
- Available Online
- View e-Book
- Location
- Online
- Available Online
- View e-Book
- Author
- Marin-Garcia, Jose
- Other Authors
- Goldenthal, Michael J
- Moe, Gordon W
- Place of Publication
- Amsterdam, Netherlands
- Publisher
- Elsevier Academic Press
- Date of Publication
- 2007
- Physical Description
- 688 p.
- ISBN
- 9780080554549
- Subjects (MeSH)
- Cardiovascular Diseases - genetics
- Contents
- Introduction to post-genomic cardiology -- Molecular and biochemical methodology in the post-genomic era -- Cardiovascular gene expression -- Cellular techniques -- Cardiovascular signaling pathways -- Cardiac development: molecular and genetic analysis -- Congenital and acquired heart disease -- Molecular basis of lipoprotein disorders, atherogenesis, and thrombosis -- Ischemia and myocardial infarction: a post-genomic analysis -- Cellular pathways and molecular events in cardioprotection -- Cardiac neovascularization: angiogenesis, arteriogenesis and vasculogenesis -- Systemic and pulmonary hypertension -- Cardiomyopathies -- Heart response to inflammation and infection -- Molecular analysis of heart failure and remodeling -- Fatty acid and glucose metabolism in cardiac disease -- Dysrhythmias and sudden death -- Gender and cardiovascular disease -- The aging heart: a post-genomic appraisal -- Future of post-genomic cardiology.
- Format
- e-Book
- Location
- Online
Principles of Molecular Cardiology
https://libcat.nshealth.ca/en/permalink/provcat29601
edited by Marschall S. Runge, Cam Patterson.
--Totowa, NJ:
Humana Press
, c2005.
- Available Online
- View e-Book
- Location
- Online
- Available Online
- View e-Book
- Author
- Runge, Marschall S
- Other Authors
- Patterson, Cam
- Responsibility
- edited by Marschall S. Runge, Cam Patterson
- Place of Publication
- Totowa, NJ
- Publisher
- Humana Press
- Date of Publication
- c2005
- Series Title
- Contemporary cardiology (Totowa, N.J. : Unnumbered)
- ISBN
- 9781592598786
- Subjects (LCSH)
- Cardiology
- Biochemistry
- Format
- e-Book
- Location
- Online
