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Aging and the heart : A Post-Genomic View

https://libcat.nshealth.ca/en/permalink/provcat28046
by José Marín-García, Michael J. Goldenthal, Gordon W. Moe. --Boston, MA: Springer Science+Business Media , c2008.
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Online
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Author
Marín-García, José
Other Authors
Goldenthal, Michael J
Moe, Gordon W
Responsibility
by José Marín-García, Michael J. Goldenthal, Gordon W. Moe
Place of Publication
Boston, MA
Publisher
Springer Science+Business Media
Date of Publication
c2008
ISBN
9780387740720
Subjects (MeSH)
Aging - physiology
Cardiovascular Diseases - genetics
Cardiovascular Diseases - physiopathology
Subjects (LCSH)
Cardiology
Geriatrics
Format
e-Book
Location
Online
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Cardiac Considerations in Chronic Lung Disease

https://libcat.nshealth.ca/en/permalink/provcat45458
Surya P. Bhatt, editor. --Cham: Humana Press , c2020.
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This book comprehensively covers chronic lung disease and cardiovascular disease and their influence on one another including the epidemiology, physiology, risk factors, pathophysiology, clinical features, diagnostic issues including laboratory and imaging tests, and therapeutic considerations. How the diseases specifically overlap is explored in detail, covering presentation, symptoms, clinical examination findings, diagnostic test results, as well as a number of important medication interacti…
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Other Authors
Bhatt, Surya P.
Responsibility
Surya P. Bhatt, editor
Place of Publication
Cham
Publisher
Humana Press
Date of Publication
c2020
Physical Description
1 online resource (xi, 272 p.) : 45 illus., 23 illus. in color
Series Title
Respiratory medicine
ISBN
9783030434359
9783030434342 (Print ed.)
9783030434366 (Print ed.)
9783030434373 (Print ed.)
ISSN
2197-7372
Subjects (MeSH)
Cardiovascular Diseases - complications
Cardiovascular Diseases - physiopathology
Comorbidity
Pulmonary Disease, Chronic Obstructive - complications
Pulmonary Disease, Chronic Obstructive - physiopathology
Specialty
Cardiology
Pulmonary Medicine
Abstract
This book comprehensively covers chronic lung disease and cardiovascular disease and their influence on one another including the epidemiology, physiology, risk factors, pathophysiology, clinical features, diagnostic issues including laboratory and imaging tests, and therapeutic considerations. How the diseases specifically overlap is explored in detail, covering presentation, symptoms, clinical examination findings, diagnostic test results, as well as a number of important medication interactions. The cardiovascular considerations in this book will include left ventricular systolic and diastolic dysfunction, pulmonary hypertension and right ventricular disease, as well as cardiac arrhythmias. The book also addresses extra-cardiac cardiovascular comorbidities such as cerebrovascular disease and peripheral arterial disease. Each chapter includes detailed illustrations as well as useful pearls and best practices, making this an ideal reference for pulmonologists, cardiologists, and residents caring for patients with increased risk for these comorbidities.
Contents
1. Cardiovascular Comorbidity in Chronic Lung Disease: Epidemiology, Clinical Manifestations, and Diagnosis -- 2. Origins of Cardiopulmonary Disease in Early Life -- 3. Cardiovascular Comorbidity in Chronic Lung Disease: Gender Differences -- 4. Pathophysiology of Cardiovascular Disease in Chronic Lung Disease -- 5. Pathophysiology of Right Heart Disease in Chronic Lung Disease -- 6. Pulmonary Hypertension Associated with Chronic Lung Diseases: Treatment Considerations -- 7. Imaging in Chronic Lung Disease: Cardiac Considerations -- 8. Cardiovascular Comorbidity in Chronic Lung Disease: The Role of Cardiopulmonary Exercise Testing -- 9. Physiology of Heart-Lung Interactions -- 10. Medication Safety in Chronic Lung Disease with Cardiac Comorbidity -- 11. Cardiovascular Co-Morbidity in Chronic Lung Disease: Exercise Training -- 12. Acute Exacerbations of Chronic Lung Disease: Cardiac Considerations -- 13. Lung Transplantation for Chronic Lung Disease: Cardiac Considerations.
Format
e-Book
Location
Online
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Cardiorenal Syndrome : Mechanisms, Risk and Treatment

https://libcat.nshealth.ca/en/permalink/provcat29194
edited by Adel E. Berbari, Giuseppe Mancia. --Milan: Springer-Verlag , c2010.
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Online
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Author
Berbari, Adel E
Other Authors
Mancia, Giuseppe
Responsibility
edited by Adel E. Berbari, Giuseppe Mancia
Place of Publication
Milan
Publisher
Springer-Verlag
Date of Publication
c2010
ISBN
9788847014633
Subjects (MeSH)
Cardiovascular Diseases - complications
Cardiovascular Diseases - physiopathology
Kidney Failure, Chronic - complications
Kidney Failure, Chronic - physiopathology
Subjects (LCSH)
Cardiology
Nephrology
Format
e-Book
Location
Online
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Cellular and molecular pathobiology of cardiovascular disease

https://libcat.nshealth.ca/en/permalink/provcat50477
Willis, Monte. (1st ed.) --Philadelphia, PA: Elsevier , 2014.
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Online
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Author
Willis, Monte
Edition
1st ed.
Place of Publication
Philadelphia, PA
Publisher
Elsevier
Date of Publication
2014
ISBN
9780124052062
Subjects (MeSH)
Cardiovascular Diseases - genetics
Cardiovascular Diseases - physiopathology
Notes
Access to this online resource is restricted to IWK Health Centre employees working from inside the hospital network.
Format
e-Book
Location
Online
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Cellular and molecular pathobiology of cardiovascular disease

https://libcat.nshealth.ca/en/permalink/provcat33110
edited by Monte S. Willis, Jonathon W. Homeister, James R. Stone. --London, UK: Elsevier / AP , c2014.
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Focuses on the pathophysiology of common cardiovascular disease in the context of its underlying mechanisms and molecular biology. This book has been developed from the editors' experiences teaching an advanced cardiovascular pathology course for PhD trainees in the biomedical sciences, and trainees in cardiology, pathology, public health, and veterinary medicine.
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Other Authors
Willis, Monte S
Homeister, Jonathon W
Stone, James R
Responsibility
edited by Monte S. Willis, Jonathon W. Homeister, James R. Stone
Place of Publication
London, UK
Publisher
Elsevier / AP
Date of Publication
c2014
Physical Description
1 online resource (xvii, 320 pages)
ISBN
9780124055254 (e-Book)
Subjects (MeSH)
Cardiovascular Diseases - genetics
Cardiovascular Diseases - physiopathology
Subjects (LCSH)
Cardiovascular system - Diseases - Molecular aspects
Cardiovascular toxicology
Cardiovascular Diseases - genetics
Cardiovascular Diseases - physiopathology
Cardiovascular diseases - Chemically induced
Abstract
Focuses on the pathophysiology of common cardiovascular disease in the context of its underlying mechanisms and molecular biology. This book has been developed from the editors' experiences teaching an advanced cardiovascular pathology course for PhD trainees in the biomedical sciences, and trainees in cardiology, pathology, public health, and veterinary medicine.
Access
Registration required for PDF access.
Format
e-Book
Location
Online
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Interdisciplinary Concepts in Cardiovascular Health. Volume I, Primary Risk Factors

https://libcat.nshealth.ca/en/permalink/provcat40815
Ichiro Wakabayashi, Klaus Groschner, editors. --Vienna: Springer , c2013.
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This book provides an introduction to the principles of both cardiovascular epidemiology and molecular pathophysiology; as a unique aspect, it also outlines and discusses the molecular concepts underlying epidemiological observations. This first volume is focused on the genetic and molecular basis of pathogenesis and the role of environmental factors triggering cardiovascular dysfunctions. The book promotes the use of interdisciplinary approaches in the field of preventive medicine based on rec…
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Other Authors
Wakabayashi, Ichiro
Groschner, Klaus
Responsibility
Ichiro Wakabayashi, Klaus Groschner, editors
Place of Publication
Vienna
Publisher
Springer
Date of Publication
c2013
Physical Description
1 online resource (xiii, 224 p. : ill.)
ISBN
9783709113349
9783709113332 (print ed.)
Subjects (MeSH)
Cardiovascular Diseases - epidemiology
Cardiovascular Diseases - physiopathology
Cardiovascular Physiological Phenomena
Risk Factors
Abstract
This book provides an introduction to the principles of both cardiovascular epidemiology and molecular pathophysiology; as a unique aspect, it also outlines and discusses the molecular concepts underlying epidemiological observations. This first volume is focused on the genetic and molecular basis of pathogenesis and the role of environmental factors triggering cardiovascular dysfunctions. The book promotes the use of interdisciplinary approaches in the field of preventive medicine based on recent advances in molecular and cellular pathophysiology. The book offers a valuable resource work for researchers in basic biomedical fields and clinical scientists alike, as well as guidelines for novel avenues of research in both basic pathophysiology and cardiovascular therapy and prevention.
Contents
1. Basic Principles of Molecular Pathophysiology and Etiology of Cardiovascular Dysorders -- 2. Aging -- 3. Gender -- 4. Gene Polymorphisms and Signaling Defects -- 5. Diet and Nutrition to Prevent and Treat Cardiovascular Diseases -- 6. Physical Activity and Cardiovascular Diseases -- 7. Alcohol -- 8. Tobacco -- 9. Socioeconomic Aspects of Cardiovascular Health -- 10. Stress and Psychological Factors.
Format
e-Book
Location
Online
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Microcirculation in Cardiovascular Diseases

https://libcat.nshealth.ca/en/permalink/provcat46069
Enrico Agabiti-Rosei, Anthony M. Heagerty, Damiano Rizzoni, editors. --Cham: Springer , c2020.
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This book offers an extensive review of the most recent data on the pathophysiological role of structural and functional alterations in the microcirculation, particularly focusing on hypertension and diabetes. It covers several relevant and innovative aspects, including the possible mechanisms involved in the development of microvascular remodeling and rarefaction, the technical approaches available for the detection of microvascular alterations, including non-invasive evaluations, the prognost…
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Other Authors
Agabiti-Rosei, Enrico
Heagerty, Anthony M.
Rizzoni, Damiano
Other Authors
European Society of Hypertension
Responsibility
Enrico Agabiti-Rosei, Anthony M. Heagerty, Damiano Rizzoni, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2020
Physical Description
1 online resource (viii, 216 p.) : 50 illus., 31 illus. in color
Series Title
Updates in hypertension and cardiovascular protection
ISBN
9783030478018
9783030478001 (Print ed.)
9783030478025 (Print ed.)
9783030478032 (Print ed.)
ISSN
2366-4606
Subjects (MeSH)
Cardiovascular Diseases - physiopathology
Hypertension - physiopathology
Microcirculation
Specialty
Cardiology
Abstract
This book offers an extensive review of the most recent data on the pathophysiological role of structural and functional alterations in the microcirculation, particularly focusing on hypertension and diabetes. It covers several relevant and innovative aspects, including the possible mechanisms involved in the development of microvascular remodeling and rarefaction, the technical approaches available for the detection of microvascular alterations, including non-invasive evaluations, the prognostic role of changes in small resistance artery structure, the possibility of preventing or regressing such alterations with appropriate treatment, and the potential clinical advantages of such intervention. A number of innovative areas of research are considered, including the role of the immune system, inflammation and oxidative stress in the development of microvascular alterations. Lastly, it examines the availability of recent non-invasive methods for the evaluation of small resistance artery morphology in the retina, which in the near future may provide a useful tool for the stratification of cardiovascular risk and even for clinical decisions regarding drug treatment, thus providing physicians with a clinically relevant instrument for improving and optimizing the management of hypertensive and diabetic patients. The book provides valuable, clinically relevant information for specialists (cardiology, internal medicine, and endocrinology) and general practitioners, and also offers novel and stimulating data to basic and clinical researchers.
Contents
1. Structure and Function of the Microcirculation -- 2. Assessment of Small Artery Structure and Function by Micromyography -- 3. Assessment of Retinal Arteriolar Morphology by SLDF -- 4. Assessment of Retinal Arteriolar Morphology by Adaptive Optics -- 5. The Cerebral Microcirculation -- 6. Role of Inflammation in Microvascular Damage -- 7. Immune Mechanisms in Vascular Remodeling in Hypertension -- 8. Microvascular Endothelial Dysfunction in Hypertension -- 9. Interrelationships Between Micro and Macrocirculation -- 10. Alterations in Capillary and Microcirculatory Networks in Cardiovascular Diseases -- 11. Microvascular Alterations in Obesity -- 12. Microvascular Alterations in Diabetes: Focus on Small Resistance Arteries -- 13. Cardiovascular Effects of Anti-angiogenic Drugs -- 14. Pathophysiological Mechanisms Implicated in Organ Damage and Cardiovascular Events -- 15. The Role of Perivascular Adipose Tissue in Arterial Function in Health and Disease -- 16. Prognostic Role of Microvascular Damage and Effect of Treatment.
Format
e-Book
Location
Online
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Mitochondria and their role in cardiovascular disease

https://libcat.nshealth.ca/en/permalink/provcat32396
by José Marín-García ; with contributions by Alexander Akhmedov and Vitalyi Rybin, Gordon W. Moe. --New York, NY: Springer , c2013.
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Over the past two decades, due to dramatic advances in molecular and cell biology, biochemistry, and genetics, our view on mitochondria as a relatively static cellular powerhouse has changed radically. We now know that these organelles play a critical role in the normal and in the damaged heart. Written by Dr. José Marín-García, Director of the Molecular Cardiology and Neuromuscular Institute, Mitochondria and Their Role in Cardiovascular Disease brings readers up- to-date on the many significa…
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Author
Marín-García, José
Responsibility
by José Marín-García ; with contributions by Alexander Akhmedov and Vitalyi Rybin, Gordon W. Moe
Place of Publication
New York, NY
Publisher
Springer
Date of Publication
c2013
Physical Description
1 online resource (xix, 500 p. : 123 ill., 115 ill. in color)
ISBN
9781461445999
Subjects (MeSH)
Cardiovascular Diseases - etiology
Cardiovascular Diseases - physiopathology
Mitochondria, Heart - metabolism
Myocardium - metabolism
Subjects (LCSH)
Cardiology
Biochemistry
Abstract
Over the past two decades, due to dramatic advances in molecular and cell biology, biochemistry, and genetics, our view on mitochondria as a relatively static cellular powerhouse has changed radically. We now know that these organelles play a critical role in the normal and in the damaged heart. Written by Dr. José Marín-García, Director of the Molecular Cardiology and Neuromuscular Institute, Mitochondria and Their Role in Cardiovascular Disease brings readers up- to-date on the many significant advances in the field of mitochondrial cardiovascular medicine. The book begins with a general introduction to mitochondria, followed by laboratory methods to study the structure and function of the organelle, regulation of replication and biogenesis, and the mechanisms and functional consequences of mitophagia and mitochondrial dynamics. Subsequent chapters deal with mitochondrial oxidative stress and the role that the organelle plays in cell signaling and cell death. Discussions will be undertaken on the biochemistry of mitochondrial cell signaling, including the nature of the proteins engaged in these processes, many of them only recently discovered. Later chapters examine the role of mitochondria and mitochondrial abnormalities in cardiovascular diseases, including their diagnosis, therapeutic options currently available, animal models of mitochondrial disease, and new frontiers in mitochondria cardiovascular medicine, including areas of research that are relatively new or developing, such as proteomics, next generation sequencing, and systems biology.
Contents
Introduction to mitochondria in the heart -- Methods to study mitochondrial structure and function- Mitochondrial structure, composition and dynamics -- Mitochondrial biogenesis -- Mechanisms of bioenergy production in mitochondria -- Bioenergetics interplay between cardiac mitochondria and other subcellular compartments -- Endothelial mitochondria: Contribution to cardiovascular function and disease -- Heart mitochondria: Receivers and transmitters of signals -- Stem cells and mitochondria -- Cell death pathways and mitochondria -- Mitochondria in pediatric cardiovascular diseases -- Mitochondrial in the aging heart -- The role of mitochondria in atherosclerosis -- The role of mitochondria in hypertension -- Role of mitochondria in ischemia and cardioprotection -- Mitochondrial dynamics in health and disease -- Mitochondria play an essential role in heart failure -- Mitochondria and cardiac dysrhythmias -- Diabetes and cardiac mitochondria -- The role of mitochondria in metabolic syndrome and insulin resistance.-Thyroid hormone and myocardial mitochondria -- Targeting the mitochondria in cardiovascular diseases -- Current progress and future perspectives: Towards mitochondrial medicine -- Glossary -- Index.
Format
e-Book
Location
Online
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Molecular Defects in Cardiovascular Disease

https://libcat.nshealth.ca/en/permalink/provcat29654
edited by Naranjan S. Dhalla, Makoto Nagano, Bohuslav Ostadal. --New York, NY: Springer Science+Business Media , c2011.
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Online
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Author
Dhalla, Naranjan S
Other Authors
Nagano, Makoto
Ostadal, Bohuslav
Responsibility
edited by Naranjan S. Dhalla, Makoto Nagano, Bohuslav Ostadal
Place of Publication
New York, NY
Publisher
Springer Science+Business Media
Date of Publication
c2011
ISBN
9781441971302
Subjects (MeSH)
Cardiovascular Diseases - pathology
Cardiovascular Diseases - physiopathology
Molecular Biology
Subjects (LCSH)
Cardiology
Biochemistry
Format
e-Book
Location
Online
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Natriuretic Peptides : The Hormones of the Heart

https://libcat.nshealth.ca/en/permalink/provcat28235
edited by Aldo Clerico, Michele Emdin. --Milan: Springer-Verlag Italia , c2006.
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Location
Online
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Author
Clerico, Aldo
Other Authors
Emdin, Michele
Responsibility
edited by Aldo Clerico, Michele Emdin
Place of Publication
Milan
Publisher
Springer-Verlag Italia
Date of Publication
c2006
ISBN
9788847004986
Subjects (MeSH)
Biological Markers
Cardiovascular Diseases - physiopathology
Natriuretic Peptides - analysis
Subjects (LCSH)
Cardiology
Endocrinology 
Format
e-Book
Location
Online
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Organ Microcirculation : A Gateway to Diagnostic and Therapeutic Interventions

https://libcat.nshealth.ca/en/permalink/provcat29378
edited by Hiromasa Ishii, Makoto Suematsu, Kazuo Tanishita, Hidekazu Suzuki. --Tokyo: Springer-Verlag , c2005.
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Location
Online
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Author
Ishii, Hiromasa
Other Authors
Keio International Symposium for Life Sciences and Medicine (14th : 2003 : Keio Gijuku Daigaku)
Other Authors
Suematsu, Makoto
Tanishita, Kazuo
Suzuki, Hidekazu
Responsibility
edited by Hiromasa Ishii, Makoto Suematsu, Kazuo Tanishita, Hidekazu Suzuki
Place of Publication
Tokyo
Publisher
Springer-Verlag
Date of Publication
c2005
Series Vol.
13
Series Title
Keio University International Symposia for Life Sciences and Medicine
ISBN
9784431271741
Subjects (MeSH)
Cardiovascular Diseases - physiopathology
Microcirculation - physiology
Subjects (LCSH)
Physiology
Format
e-Book
Location
Online
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Pathophysiology and Pharmacotherapy of Cardiovascular Disease

https://libcat.nshealth.ca/en/permalink/provcat39236
Gowraganahalli Jagadeesh, Pitchai Balakumar, Khin Maung-U, editors. --Cham: Springer International Publishing : Imprint: Adis , c2015.
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The present book covers the basic principles of cardiovascular physiology, pathophysiology and advanced pharmacology with particular emphasis on cellular mechanisms of drug action. It provides an update on the progress made in several aspects of cardiovascular diseases so that it might kindle scientists and clinicians alike in furthering basic and translational research. In addition, the book is expected to fill imperative gaps in understanding and optimally treating cardiovascular disease.
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Other Authors
Jagadeesh, Gowraganahalli
Balakumar, Pitchai
Maung-U, Khin
Responsibility
Gowraganahalli Jagadeesh, Pitchai Balakumar, Khin Maung-U, editors
Place of Publication
Cham
Publisher
Springer International Publishing : Imprint: Adis
Date of Publication
c2015
Physical Description
1 online resource (xxiii, 1342 p. : 181 illus., 107 illus. in color)
ISBN
9783319159614
9783319159607 (print ed.)
Subjects (MeSH)
Cardiovascular Diseases - drug therapy
Cardiovascular Diseases - physiopathology
Abstract
The present book covers the basic principles of cardiovascular physiology, pathophysiology and advanced pharmacology with particular emphasis on cellular mechanisms of drug action. It provides an update on the progress made in several aspects of cardiovascular diseases so that it might kindle scientists and clinicians alike in furthering basic and translational research. In addition, the book is expected to fill imperative gaps in understanding and optimally treating cardiovascular disease.
Contents
Part I. Heart Failure -- Part II. Cardiac Hypertrophy and Cardiomyopathy -- Part III. Coronary Heart Disease -- Part IV. Atherosclerosis and Hyperlipidemia -- Part V. Hypertension -- Part VI. Cardiac Arrhythmias -- Part VII. Valvular Heart Disease -- Part VIII. Cardiovascular Conditions of Childhood and Pregnancy.
Format
e-Book
Location
Online
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Principles of Molecular Cardiology

https://libcat.nshealth.ca/en/permalink/provcat29601
edited by Marschall S. Runge, Cam Patterson. --Totowa, NJ: Humana Press , c2005.
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Location
Online
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Author
Runge, Marschall S
Other Authors
Patterson, Cam
Responsibility
edited by Marschall S. Runge, Cam Patterson
Place of Publication
Totowa, NJ
Publisher
Humana Press
Date of Publication
c2005
Series Title
Contemporary cardiology (Totowa, N.J. : Unnumbered)
ISBN
9781592598786
Subjects (MeSH)
Cardiovascular Diseases - genetics
Cardiovascular Diseases - physiopathology
Subjects (LCSH)
Cardiology
Biochemistry
Format
e-Book
Location
Online
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Renin Angiotensin System and Cardiovascular Disease

https://libcat.nshealth.ca/en/permalink/provcat29131
edited by Walmor C. DeMello, Edward D. Frohlich. --Totowa, NJ: Humana Press , c2010.
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Online
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Author
DeMello, Walmor C.
Other Authors
Frohlich, Edward D.
Responsibility
edited by Walmor C. DeMello, Edward D. Frohlich
Place of Publication
Totowa, NJ
Publisher
Humana Press
Date of Publication
c2010
Series Title
Contemporary cardiology (Totowa, N.J. : Unnumbered)
ISBN
9781607611868
Subjects (MeSH)
Cardiovascular Diseases - physiopathology
Receptors, Angiotensin - therapeutic use
Renin-Angiotensin System - physiology
Format
e-Book
Location
Online
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14 records – page 1 of 1.