Clinical trials : a methodologic perspective
https://libcat.nshealth.ca/en/permalink/provcat22583
Piantadosi, Steven.
(2nd ed.)
--Hoboken, NJ:
Wiley-Interscience
, 2005.
- Call Number
- WA 950 P581c 2005
- Location
- Halifax Infirmary
- Call Number
- WA 950 P581c 2005
- Author
- Piantadosi, Steven
- Edition
- 2nd ed.
- Place of Publication
- Hoboken, NJ
- Publisher
- Wiley-Interscience
- Date of Publication
- 2005
- Physical Description
- 687 p.
- Series Title
- Wiley series in probability and statistics
- ISBN
- 0471727814
- Format
- Book
- Location
- Halifax Infirmary
- Loan Period
- 3 weeks
eClinical trials : planning and implementation
https://libcat.nshealth.ca/en/permalink/provcat22415
Kush, Rebecca Daniels.
--Boston, MA:
Thomson CenterWatch
, 2003.
- Call Number
- WA 20.5 K97e 2003
- Location
- Nova Scotia Hospital
- Call Number
- WA 20.5 K97e 2003
- Author
- Kush, Rebecca Daniels
- Other Authors
- Bleicher, Paul
- Place of Publication
- Boston, MA
- Publisher
- Thomson CenterWatch
- Date of Publication
- 2003
- Physical Description
- 194 p.
- ISBN
- 193062428X
- Subjects (MeSH)
- Clinical Trials as Topic - methods
- Medical Informatics
- Format
- Book
- Location
- Nova Scotia Hospital
- Loan Period
- 3 weeks
Essentials of clinical research
https://libcat.nshealth.ca/en/permalink/provcat33263
Stephen P. Glasser, editor.
(Second edition)
--Cham, Switzerland:
Springer
, c2014.
- Available Online
- View e-Book
- Location
- Online
In its extensively revised and updated Second Edition, this book provides a solid foundation for readers interested in clinical research. Discussion encompasses genetic, pharmacoepidemiologic and implementation research. All chapters have been updated with new information and many new tables have been added to elucidate key points. The book now offers discussion on how to handle missing data when analyzing results, and coverage of Adaptive Designs and Effectiveness Designs and new sections on C…
- Available Online
- View e-Book
- Other Authors
- Glasser, Stephen P
- Responsibility
- Stephen P. Glasser, editor
- Edition
- Second edition
- Place of Publication
- Cham, Switzerland
- Publisher
- Springer
- Date of Publication
- c2014
- Physical Description
- 1 online resource (vi, 461 pages)
- ISBN
- 9783319054704 (electronic bk.)
- 9783319054698
- Subjects (MeSH)
- Biomedical Research - methods
- Clinical Trials as Topic - methods
- Statistics as Topic - methods
- Abstract
- In its extensively revised and updated Second Edition, this book provides a solid foundation for readers interested in clinical research. Discussion encompasses genetic, pharmacoepidemiologic and implementation research. All chapters have been updated with new information and many new tables have been added to elucidate key points. The book now offers discussion on how to handle missing data when analyzing results, and coverage of Adaptive Designs and Effectiveness Designs and new sections on Comparative Effectiveness Research and Pragmatic Trials. Chapter 6 includes new material on Phase 0 Trials, expanded coverage of Futility Trials, a discussion of Medical Device approval, Off Label Drug use and the role of the FDA in regulating advertising. Additional new information includes the role of pill color and shape in association with the placebo effect and an examination of issues surrounding minority recruitment. The final chapter offers a new section on manuscript preparation along with a discussion of various guidelines being adopted by journals: CONSORT, STROBE, PRISMA, MOOSE and others; and coverage of Conflicts of Interest, Authorship, Coercive Citation, and Disclosures in Industry-Related Associations. Building on the strengths of its predecessor in its comprehensive approach and authoritative advice, the new edition offers more of what has made this book a popular, trusted resource for students and working researchers alike.
- Contents
- The Beginning - Historical Aspects of Clinical Research, Clinical Research: Definitions, "Anatomy and Physiology," and the Quest for "Universal Truth" -- Introduction to Clinical Research Concepts, Essential Characteristics of Clinical Research, Overview of Clinical Research Study Designs -- A Focus on Clinical Trials -- Alternative Interventional Study Designs -- Phase 4 (Postmarketing) Research -- The Role of the USA Food and Drug Administration in Clinical Research -- The Placebo and Nocebo Effect -- Recruitment and Retention in Clinical Research -- Data Safety and Monitoring Boards (DSMBs) -- Meta-analysis, Evidence-Based Medicine, and Clinical Guidelines -- Research Methods for Genetic Studies -- Research Methods for Pharmacoepidemiology Studies -- Implementation Research: Beyond the Traditional Randomized Controlled Trial -- Research Methodology for Studies of Diagnostic Tests -- Statistical Power and Sample Size: Some Fundamentals for Clinician Researchers -- Association, Cause, and Correlation -- Bias, Confounding, and Effect Modification (Interaction) -- It's All About Uncertainty -- Grant and Manuscript Writing -- The Media and Clinical Research -- Mentoring and Advising -- Presentation Skills: How to Present Research Results.
- Format
- e-Book
- Location
- Online
A manager's guide to the design and conduct of clinical trials
https://libcat.nshealth.ca/en/permalink/provcat22576
Good, Philip I.
(2nd ed.)
--Hoboken, NJ:
Wiley-Liss
, 2006.
- Call Number
- W 20.5 G646m 2006
- Location
- Halifax Infirmary
- Call Number
- W 20.5 G646m 2006
- Author
- Good, Philip I.
- Edition
- 2nd ed.
- Place of Publication
- Hoboken, NJ
- Publisher
- Wiley-Liss
- Date of Publication
- 2006
- Physical Description
- 256 p.
- ISBN
- 0471788708
- 9780471788706
- Subjects (MeSH)
- Clinical Trials as Topic - methods
- Research Design
- Format
- Book
- Location
- Halifax Infirmary
- Loan Period
- 3 weeks
Statistics applied to clinical trials
https://libcat.nshealth.ca/en/permalink/provcat22575
Cleophas, Ton J.
(3rd ed.)
--Dordrecht, Netherlands:
Springer
, 2006.
- Call Number
- WA 950 C628s 2006
- Location
- Halifax Infirmary
- Call Number
- WA 950 C628s 2006
- Author
- Cleophas, Ton J.
- Other Authors
- Zwinderman, Aeilko H.
- Cleophas, Toine F.
- Edition
- 3rd ed.
- Place of Publication
- Dordrecht, Netherlands
- Publisher
- Springer
- Date of Publication
- 2006
- Physical Description
- 366 p.
- ISBN
- 1402042299
- 9781402042294
- Subjects (MeSH)
- Clinical Trials as Topic - methods
- Data Interpretation, Statistical
- Format
- Book
- Location
- Halifax Infirmary
- Loan Period
- 3 weeks
Success in academic surgery : clinical trials
https://libcat.nshealth.ca/en/permalink/provcat33400
Timothy M. Pawlik, Julie A. Sosa, editors.
--London:
Springer
, c2014.
- Available Online
- View e-Book
- Location
- Online
- Available Online
- View e-Book
- Other Authors
- Pawlik, Timothy M
- Sosa, Julie Ann
- Responsibility
- Timothy M. Pawlik, Julie A. Sosa, editors
- Alternate Title
- Clinical trials
- Place of Publication
- London
- Publisher
- Springer
- Date of Publication
- c2014
- Physical Description
- 1 online resource (xix, 183 pages)
- Series Title
- Success in academic surgery
- ISBN
- 9781447146797 (electronic bk.)
- 9781447146780
- Contents
- Building Your Clinical Trial Research Team -- Clinical Trials: Ensuring Quality and Standardization -- Statistics: Setting the Stage -- Clinical Trials: Handling the Data -- Data Safety Monitoring Boards -- Planning for Data Monitoring and Audits -- The Budget -- Regulatory Considerations in Human Subjects Research -- Publishing a Clinical Trial -- Device Versus Drug Clinical Trials: Similarities and Important Differences -- Defining the Study Cohort: Inclusion and Exclusion Criteria -- The History of Clinical Trials -- Ethics of Clinical Trials -- Trial Design: Overview of Study Designs (Phase I, II, III, IV, Factorial Design).
- Format
- e-Book
- Location
- Online
