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Fibrostenotic Inflammatory Bowel Disease

https://libcat.nshealth.ca/en/permalink/provcat42704
edited by Florian Rieder. --Cham: Springer , c2018.
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This book provides a comprehensive account of the pathogenesis and treatment of intestinal fibrosis, covering both the clinical and molecular aspects of the disease. It begins by describing the epidemiology and genetics of fibrostenosing IBD in Crohn's disease and Ulcerative colitis as well as the epigenetics and cellular and molecular mechanisms of the disease. Readers will obtain an in-depth overview of the disease from biomarkers and histology to surgical intervention, imaging and current an…
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Other Authors
Rieder, Florian
Responsibility
edited by Florian Rieder
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2018
Physical Description
1 online resource (xii, 397 p.) : 70 illus., 67 illus. in color
ISBN
9783319905785
9783319905778 (print ed.)
9783319905792 (print ed.)
Subjects (MeSH)
Fibrosis
Crohn Disease
Colitis, Ulcerative
Specialty
Gastroenterology
Abstract
This book provides a comprehensive account of the pathogenesis and treatment of intestinal fibrosis, covering both the clinical and molecular aspects of the disease. It begins by describing the epidemiology and genetics of fibrostenosing IBD in Crohn's disease and Ulcerative colitis as well as the epigenetics and cellular and molecular mechanisms of the disease. Readers will obtain an in-depth overview of the disease from biomarkers and histology to surgical intervention, imaging and current and future drug therapies. Medical management of fibrosis, endoscopy and imaging as well as surgical approaches are all discussed. Through the links to videos contained in the book, the reader will become familiar with interventional procedures such as endoscopic balloon dilation and surgical techniques for stricturing IBD, such as resection and strictureplasties. This is an indispensable volume for anyone working on fibrostenotic IBD, such as gastroenterologists, internists, radiologists, colorectal surgeons, pathologists and researchers. It has been written by a team of top experts from North America, Asia and Europe.
Contents
Fibrostenotic Inflammatory Bowel Disease—a Cinderella story -- Epidemiology and Natural History of Fibrostenosing Inflammatory Bowel Disease -- Genetic influences on the development of fibrosis in inflammatory bowel disease -- Epigenetic regulation of intestinal fibrosis -- Cytokine and Anti-cytokine Agents as Future Therapeutics for Fibrostenosing IBD -- Inflammation-independent mechanisms of intestinal fibrosis: the role of the extracellular matrix -- Fat and Fibrosis -- Environmental factors and their influence on intestinal fibrosis -- Animal models and sources of mesenchymal cells in intestinal fibrosis -- Fibrosis in Ulcerative Colitis -- Histopathology of intestinal fibrosis -- Clinical, Cellular and Serologic Biomarkers of intestinal fibrosis -- The future of intestinal fibrosis imaging -- Imaging in intestinal fibrosis. What is state of the art? -- Medical therapy of stricturing IBD -- Endoscopic therapy of intestinal strictures Çô What is state of the art? -- Resectional surgery for intestinal strictures Çô What is state of the art? -- Management of ileal pouch strictures and anal stricturing disease—A clinical challenge -- The future of surgical therapy of stricturing IBD -- Challenges of translation of anti-fibrotic therapies into clinical practice in IBD -- What distinguishes mechanisms of fistula and stricture formation -- The Pathogenesis of Intraabdominal Adhesions:Similarities and Differences to Luminal Fibrosis -- Anti-fibrotic therapies from other organs—What the gut can learn from the liver, skin, lung and heart.
Format
e-Book
Location
Online
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Mastery of IBD Surgery

https://libcat.nshealth.ca/en/permalink/provcat44458
Neil Hyman, Phillip Fleshner, Scott Strong, editors. --Cham: Springer , c2019.
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This book provides a guide to the management of patients with Crohn’s disease and ulcerative colitis. The indications for surgery within inflammatory bowel disease are covered, as well as new biologic medications and the effects they have on the immune system. Details on how these drugs should be managed to avoid complications and ensure patient safety are also included. Mastery of IBD Surgery sets out to cover surgical responses to inflammatory bowel disease from a multidisciplinary perspectiv…
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Other Authors
Hyman, Neil
Fleshner, Phillip
Strong, Scott
Responsibility
Neil Hyman, Phillip Fleshner, Scott Strong, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2019
Physical Description
1 online resource (xi, 409 p.) : 8 illus. in color
ISBN
9783030167554
9783030167547 (Print ed.)
9783030167561 (Print ed.)
9783030167578 (Print ed.)
Subjects (MeSH)
Colitis, Ulcerative - surgery
Crohn Disease - surgery
Inflammatory Bowel Diseases - therapy
Specialty
Colorectal Surgery
Abstract
This book provides a guide to the management of patients with Crohn’s disease and ulcerative colitis. The indications for surgery within inflammatory bowel disease are covered, as well as new biologic medications and the effects they have on the immune system. Details on how these drugs should be managed to avoid complications and ensure patient safety are also included. Mastery of IBD Surgery sets out to cover surgical responses to inflammatory bowel disease from a multidisciplinary perspective and aims to help all surgeons and medical professionals working in this area. This book is relevant to colorectal surgeons, gastrointestinal surgeons, and gastroenterologists.
Contents
Nutritional Repletion in the Surgical Patient -- Preoperative Bowel Prep -- Extended Venous Thromboembolism Prophylaxis after Surgery for Inflammatory Bowel Diseases -- The Use of Enhanced Recovery Pathways in Patients Undergoing Surgery for Inflammatory Bowel Disease -- Perioperative Steroid Management in IBD Patients Undergoing Colorectal Surgery -- Managing Immunomodulators Perioperatively -- Managing Biologics Perioperatively -- Management of Perianal Skin Tags -- Management of Chronic Anal Fissures in Patients with Crohn’s Disease -- Management of Simple Anoperineal Fistulas -- Management of Severe Anoperineal Disease -- Management of Ano/Rectovaginal Fistula -- Proctectomy in Patients with “Watering Can” Perineum -- Management of Isolated Proctitis/Proctosigmoiditis -- Role of IPAA for Crohn’s Disease -- Surgical Options for Neoplasia Complicating Crohn’s Disease of the Large Intestine -- The Role of Segmental Resection for Colon Disease -- Role of Percutaneous Drainage for Disease-Related Abscesses -- Management After Successful Percutaneous Drainage of Disease-Related Abscess -- Intraoperative Detection of Upper Gastrointestinal Strictures -- Management of Long Segment Small Bowel Crohn’s Disease -- Construction of the Ideal Ileocolic Anastomosis in Crohn’s Disease -- Management of Enteroenteric Fistula -- Preventing Postoperative Crohn’s Disease Recurrence -- Role of Minimally Invasive Reoperative Surgery -- Extent of Mesenteric Resection -- Role of Endoscopic Management in Ulcerative Colitis Patients with Dysplasia -- Surgical Options for Endoscopically Unresectable Dysplasia in Ulcerative Colitis -- Management of Ulcerative Colitis in Patients with Rectal Cancer -- Surgical Approach to the Older Ulcerative Colitis Patient -- Role of Minimally Invasive Surgery in Pouch Surgery -- How Many Stages Should We Use in Pouch Surgery? -- Optimal Design for Ileal-Pouch Anal Anastomosis -- Failed Pouch-Pouch Excision vs Redo -- Mucosectomy Versus Stapled Ileal Pouch-Anal Anastomosis -- Transanal Proctectomy and Ileoanal Pouch Procedure (ta-J Pouch) -- Use of Antiadhesive Barriers in Pouch Surgery -- Optimal Management of Pelvic Abscess after Pouch Surgery -- Management of Chronic Pouchitis -- Management of Ileal Pouch Vaginal Fistulas -- Management of IPAA-Associated Persistent Presacral Sinus -- The Management of Patients with Dysplasia in the Anal Transitional Zone -- Pouch Excision Versus Diversion for the Failed Pouch -- Pouch Excision vs. Redo IPAA After a Failed Pouch -- Continent Ileostomy after Removal of a Failed IPAA.
Format
e-Book
Location
Online
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