Challenges in colorectal cancer
https://libcat.nshealth.ca/en/permalink/provcat27679
Scholefield, John.
(2nd ed.)
--Hoboken, NJ:
John Wiley & Sons
, 2008.
- Available Online
- View e-Book
- Location
- Online
- Available Online
- View e-Book
- Author
- Scholefield, John
- Other Authors
- Grothey, Axel
- Edition
- 2nd ed.
- Place of Publication
- Hoboken, NJ
- Publisher
- John Wiley & Sons
- Date of Publication
- 2008
- ISBN
- 9780470753231
- Subjects (MeSH)
- Colorectal Neoplasms - complications
- Format
- e-Book
- Location
- Online
Colorectal Cancer Liver Metastases : A Comprehensive Guide to Management
https://libcat.nshealth.ca/en/permalink/provcat44873
Mauro Monteiro Correia, Michael A. Choti, Flavio G. Rocha, Go Wakabayashi, editors.
--Cham:
Springer
, c2020.
- Available Online
- View e-Book
- Location
- Online
Colorectal cancer is the third most commonly diagnosed condition in oncology, affecting around 1.23 million individuals per year, according to recent statistics. Of these patients, about 50% will develop liver metastases and approximately 20% will present a stage IV disease at diagnosis. These statistics make colorectal liver metastases (CLM) an issue of major importance in current oncology. The area of CLM is subject to great and continuous advances, as its pathophysiologic mechanisms are bett…
- Available Online
- View e-Book
- Responsibility
- Mauro Monteiro Correia, Michael A. Choti, Flavio G. Rocha, Go Wakabayashi, editors
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2020
- Physical Description
- 1 online resource (xvii, 598 p.) : 97 illus., 67 illus. in color
- ISBN
- 9783030254865
- 9783030254858 (Print ed.)
- 9783030254872 (Print ed.)
- 9783030254889 (Print ed.)
- Subjects (MeSH)
- Colorectal Neoplasms - complications
- Liver Neoplasms - secondary
- Neoplasm Metastasis - diagnosis
- Neoplasm Metastasis - therapy
- Prognosis
- Specialty
- Gastroenterology
- Medical Oncology
- Abstract
- Colorectal cancer is the third most commonly diagnosed condition in oncology, affecting around 1.23 million individuals per year, according to recent statistics. Of these patients, about 50% will develop liver metastases and approximately 20% will present a stage IV disease at diagnosis. These statistics make colorectal liver metastases (CLM) an issue of major importance in current oncology. The area of CLM is subject to great and continuous advances, as its pathophysiologic mechanisms are better understood and more therapeutic and surgical options are developed. Consequently, all professionals involved with the diagnosis, treatment and follow up of CLM should be kept up to date with the latest advances on the field, to provide high standard medical care to their patients. This book is designed to present the state-of-the-art in CLM management and, in doing so, to review the current evidence on CLM, discussing all important topics in the field. Coverage is broad and comprehensive, encompassing introductory topics (history, definitions, epidemiology, etc.), basic science subjects (molecular biology, genetics, dissemination process, etc.) and practical clinical topics (tumor behavior, diagnosis, drug therapy, radiation therapy, surgery, ablation, multidisciplinary teams, etc.). Although comprehensive on the coverage and selection of topics, each chapter is concise and objective, dissecting topics in a practical and direct format. Evidences and recommendations are included. Chapters display a brief introduction of the common knowledge, go straight to the detailed revision of the most recent years of the literature, and end with practical closing observations. This book is a tool for professionals (general and cancer surgeons, HPB surgeons, clinical oncologists, gastroenterologists and medical residents) and interns who search for a qualified and reader friendly revision on topics concerning Colorectal Cancer Liver Metastases.
- Contents
- 1. Surgical Treatment of Colorectal Cancer Liver Metastases (CRLM) - Historical Aspects -- 2. The Biology of Colorectal Liver Metastases -- 3. Molecular Biomarkers for the Management of Colorectal Cancer Liver Metastases -- 4. Diagnosis of Colorectal Liver Metastases -- 5. Role of Imaging in the Management of Patients with Potentially Resectable CRLM -- 6. Staging Classifications of Colorectal Liver Metastases -- 7. Prognostic Factors of Colorectal Cancer Liver Metastasis -- 8. Clinical Scoring Systems for Colorectal Cancer Liver Metastases -- 9. What Is the Impact of Positive Margins in the Liver? -- 10. Multidisciplinary Team (MDT) and the Management of Colorectal Cancer Liver Metastases -- 11. Defining Resectability of Colorectal Cancer Liver Metastases: Technical and Oncologic Perspectives -- 12. Algorithms for Patients with Colorectal Liver Metastasis -- 13. Treatment Options for Resectable Colorectal Liver Metastases in the Presence of Extrahepatic Disease -- 14. Anatomical, Physiological, and Kinetic Evaluation of the Future Liver Remnant of CRLM After Portal Vein Embolisation -- 15. Systemic Therapy for Colorectal Cancer Liver Metastases: Sorting Through the Options -- 16. Neoadjuvant Chemotherapy for Resectable Colorectal Cancer Liver Metastases: Indications and Results -- 17. Management of Disappearing Liver Metastasis Following Preoperative Chemotherapy -- 18. Conversion Chemotherapy for CRLM-Best Associations, and Does Conversion Translate into Longer Survival? -- 19. Adjuvant Chemotherapy for CRLM: Indications and Results -- 20. Surgical Outcome of Colorectal Cancer Liver Metastases in Our Facility: Efficacy of Conversion Surgery in Initially Unresectable Colorectal Liver Metastases -- 21. Immunotherapy in the Management of Colorectal Cancer Liver Metastasis -- 22. Adjuvant Hepatic Arterial Infusion Therapy -- 23. Sequencing of Systemic Chemotherapy for Unresectable CRLM -- 24. Role of Hepatic Artery Infusion Pump Chemotherapy for Unresectable Colorectal Cancer Liver Metastases -- 25. Enhanced Recovery After Liver Surgery -- 26. Surgical Results for Synchronous Colorectal Cancer Liver Metastases -- 27. Resection of Metachronous Colorectal Cancer Liver Metastases: Surgical Outcomes -- 28. Laparoscopic Resections for Colorectal Cancer Liver Metastases -- 29. Robotic Partial Hepatectomy for Colorectal Cancer Liver Metastases -- 30. Navigation and Augmented Reality for Liver Surgery -- 31. Staged Hepatectomies for Colorectal Cancer Liver Metastases: When and How -- 32. Parenchymal-Sparing Surgery: What Is Behind It? -- 33. Resection of the Primary in Unresectable Colorectal Cancer Liver Metastases – Is It Worth? -- 34. Liver Pedicle Lymphadenectomy: How and When? -- 35. ALPPS for Colorectal Cancer Liver Metastases—Short and Long-Term Results -- 36. Ablative Techniques for CRLM: Alone or in Association -- 37. Chemoembolization for Colorectal Liver Metastases -- 38. Role of Y90 Radioembolization in Hepatic Metastatic Colorectal Carcinoma -- 39. Liver Transplantation for CRLM—Is It Ever Indicated? -- 40. External Radiation for Unresectable CRLM -- 41. Lessons from Collaborative Big Data—Insights from LiverMetSurvey Registry -- 42. Prognosis and Management of Recurrent Metastatic Colorectal Cancer.
- Format
- e-Book
- Location
- Online
Complexities in colorectal surgery : decision-making and management
https://libcat.nshealth.ca/en/permalink/provcat33725
Scott R. Steele, Justin A. Maykel, Bradley J. Champagne, Guy R. Orangio, editors.
--New York:
Springer
, c2014.
- Available Online
- View e-Book
- Location
- Online
Complexities in Colorectal Surgery: Decision-Making and Management provides a unique, modern, practical guide that covers the strategic evaluation, specific approaches, and detailed management techniques utilized by expert colorectal surgeons caring for patients with complex problems whether they result from underlying colorectal disease or from complications arising from previous surgical therapy. The text is formatted as both a "how-to" manual as well as an algorithm-based guide allowing the …
- Available Online
- View e-Book
- Other Authors
- Steele, Scott R
- Responsibility
- Scott R. Steele, Justin A. Maykel, Bradley J. Champagne, Guy R. Orangio, editors
- Place of Publication
- New York
- Publisher
- Springer
- Date of Publication
- c2014
- Physical Description
- 1 online resource (xix, 632 pages)
- ISBN
- 9781461490227 (electronic bk.)
- 9781461490210
- Subjects (MeSH)
- Colorectal Neoplasms - complications
- Colorectal Surgery - adverse effects
- Intraoperative Complications
- Postoperative Complications
- Subjects (LCSH)
- Colon (Anatomy) - Surgery
- Rectum—Surgery
- Colorectal Surgery
- Surgical oncology
- General Surgery
- Abstract
- Complexities in Colorectal Surgery: Decision-Making and Management provides a unique, modern, practical guide that covers the strategic evaluation, specific approaches, and detailed management techniques utilized by expert colorectal surgeons caring for patients with complex problems whether they result from underlying colorectal disease or from complications arising from previous surgical therapy. The text is formatted as both a "how-to" manual as well as an algorithm-based guide allowing the reader to understand the thought process behind the proposed treatment strategies. By making use of evidence-based recommendations, each chapter will include not only diagnostic and therapeutic guidelines, but also a narrative by the author on his/her operative technical details and perioperative "tips and tricks" that they utilize in the management of these complex surgical challenges. This test includes chapters on the assessment of risk and nutritional intervention methods utilized to minimize perioperative complications. In addition, sections on medical and surgical therapies for abdominal, pelvic and anorectal disease are incorporated. Moreover, the technical challenges of managing complications resulting from the original or subsequent operations is addressed. The underlying focus throughout the text is to provide pragmatic and understandable solutions that can be readily implemented by surgeons of varying experience to successfully treat complex colorectal problems. The text also goes beyond the technical aspects of colorectal surgery and includes special sections highlighting the essence of a surgeon. These include chapters describing the importance of the first encounter, building patient rapport, and demonstrating confidence and competence while showing humility and avoiding arrogance. Additionally, aspects involving the medical-legal, ethical, and economic challenges confronting surgeons are covered.
- Format
- e-Book
- Location
- Online
Extreme Hepatic Surgery and Other Strategies : Increasing Resectability in Colorectal Liver Metastases
https://libcat.nshealth.ca/en/permalink/provcat41253
Eduardo de Santibañes, Victoria Ardiles, Fernando A. Alvarez, Virginia Cano Busnelli, Martin de Santibañes, editors.
--Cham:
Springer
, 2017.
- Available Online
- View e-Book
- Location
- Online
This book describes the diagnoses; staging and management of patients with colorectal liver metastases initially considered unresectable and portrays the different strategies to increase resectability along with their tactics and tricks. Colorectal carcinoma is the third most commonly diagnosed cancer in the world and according to recent cancer statistics around 1.23 million patients are diagnosed each year. Of these patients, approximately 50% will develop liver metastases during the course of…
- Available Online
- View e-Book
- Other Authors
- de Santibañes, Eduardo
- Ardiles, Victoria
- Alvarez, Fernando A.
- Busnelli, Virginia Cano
- de Santibañes, Martin
- Responsibility
- Eduardo de Santibañes, Victoria Ardiles, Fernando A. Alvarez, Virginia Cano Busnelli, Martin de Santibañes, editors
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- 2017
- Physical Description
- 1 online resource (xix, 383 pages) : 170 illus., 137 illus. in color
- ISBN
- 9783319138961
- 9783319138954 (print ed.)
- Subjects (MeSH)
- Colorectal Neoplasms - complications
- Liver Neoplasms - secondary
- Liver Neoplasms - surgery
- Abstract
- This book describes the diagnoses; staging and management of patients with colorectal liver metastases initially considered unresectable and portrays the different strategies to increase resectability along with their tactics and tricks. Colorectal carcinoma is the third most commonly diagnosed cancer in the world and according to recent cancer statistics around 1.23 million patients are diagnosed each year. Of these patients, approximately 50% will develop liver metastases during the course of their disease and around 15-25% are found to have stage IV disease at diagnosis. Liver resection has been recognized as the treatment of choice for these patients, offering overall 5-year survival rates of up to 50-60% and the only hope for cure. However, at diagnosis only 10-20% of these patients are possibly amenable to surgical resection with curative intent. The possibility to achieve an R0 resection is many times limited by the amount and quality of the future liver remnant (FLR), being posthepatectomy liver failure (PHLF) the most feared and severe complication after major liver resections. With the years, diverse strategies have been developed with the intention to increase resectability by increasing the future liver remnant and/or reducing tumor size, e.g. ALPPS. Along with these techniques, associated surgeries are developed including multivisceral resections, which broadens even more the resectability for patients.
- Contents
- Part I: Global Patient Evaluation and Oncological Assessment -- 1. Liver Surgical Anatomy -- 2. Resectability Assessment with Diagnostic Imaging -- 3. Preoperative Evaluation of Liver Function -- 4. Imaging-Based Preoperative Planning -- 5. Choosing the Best Strategy -- Part II: Non-operative Multimodal Therapies -- 6. Conversion and Neoadjuvant Therapies -- 7. Portal Vein Embolization -- 8. Intra-Arterial Chemotherapy -- 9. Radioembolization -- Part III: Surgical Strategies -- 10. Anesthetic Management -- 11. Intraoperative Evaluation of Resectability -- 12. Vascular Control in Major Hepatic Resections -- 13. Two-Stage Liver Surgery -- 14. Two-Stage Liver Surgery with Portal Vein Occlusion -- 15. Associating Liver Partition and Portal Vein Ligation for Staged Hepatectomy (ALPPS) -- 16. Parenchymal-Sparing Liver Resections -- 17. Combined Vascular Resections -- 18. Ex-Vivo Liver Surgery -- 19. The Role of Laparoscopy in Advanced Liver Disease -- 20. Liver Transplantation for Unresectable Disease -- Part IV: Management of Concomitant Extrahepatic Disease -- 21. Lung Metastases -- 22. Nodal Involvement -- 23. Peritoneal Metastases -- 24. Adjacent Organs Invasion: Multivisceral Resections -- Part V: Miscellany -- 25. Postoperative Complications and Their Management -- 26. Improving Quality of Life in Patients with Unresectable Disease.
- Format
- e-Book
- Location
- Online
Multidisciplinary Management of Liver Metastases in Colorectal Cancer : Early Diagnosis and Treatment
https://libcat.nshealth.ca/en/permalink/provcat41935
Xinyu Qin, Jianmin Xu, Yunshi Zhong, editors.
--Dordrecht:
Springer
, 2017.
- Available Online
- View e-Book
- Location
- Online
This book focuses on early diagnosis and multidisciplinary treatment, which is the key to preventing the occurrence of the liver metastases in colorectal cancer, and to increasing the resection rate of the liver metastasis foci and the 5-year survival after surgery. This book is divided into five parts: the introduction, basics, diagnosis, treatment and prevention. It has 20 chapters in total, covering the latest advances in colorectal cancer liver metastases epidemiology, pathogenesis, molecul…
- Available Online
- View e-Book
- Other Authors
- Qin, Xinyu
- Xu, Jianmin
- Zhong, Yunshi
- Responsibility
- Xinyu Qin, Jianmin Xu, Yunshi Zhong, editors
- Place of Publication
- Dordrecht
- Publisher
- Springer
- Date of Publication
- 2017
- Physical Description
- 1 online resource (vi, 288 pages) : 73 illus., 48 illus. in color
- ISBN
- 9789401777551
- 9789401777537 (print ed.)
- Subjects (MeSH)
- Colorectal Neoplasms - complications
- Liver Neoplasms
- Neoplasm Metastasis
- Abstract
- This book focuses on early diagnosis and multidisciplinary treatment, which is the key to preventing the occurrence of the liver metastases in colorectal cancer, and to increasing the resection rate of the liver metastasis foci and the 5-year survival after surgery. This book is divided into five parts: the introduction, basics, diagnosis, treatment and prevention. It has 20 chapters in total, covering the latest advances in colorectal cancer liver metastases epidemiology, pathogenesis, molecular diagnostics, marker screening, imaging technology, surgery, chemotherapy and prevention, etc. It provides professionals with up-to-date and comprehensive information on colorectal liver metastases. This book is relevant for senior surgeons and physicians working in oncology, general surgery, chemotherapy, digestive medicine, liver medicine and hepatic surgery. Editors Xinyu Qin and Jianmin Xu are Professors at the Department of General Surgery, Zhongshan Hospital, Fudan University, Shanghai, China. Editor Yunshi Zhong is an Associate Professor at the same department.
- Contents
- Present Situation and Prospect of Diagnosis and Treatment of Colorectal Cancer -- Diagnosis and treatment of liver metastases -- Molecular Mechanism of Hepatic Metastasis of Colorectal Cancer -- Metastatic Liver Cancer and Microenvironment -- Screening and Identification of Molecular Marker for Metastatic Liver Cancer -- Genetic Diagnosis on Hepatic Metastasis from Colorectal Cancer -- Diagnostic Value of Ultrasound in Metastatic Liver Cancer -- The Differential Diagnosis of Hepatic Metastasis by CT and MRI -- Diagnostic Value of PET/CT in Metastatic Liver Cancer -- Surgical Treatment of Rectal Cancer -- Laparoscopic Resection for Colorectal Cancer -- New Neoadjuvant Chemotherapy of Resectable Liver Metastases of Colorectal -- Surgical Techniques for Metastatic Hepatic Carcinoma -- Laparoscopic Management of Colorectal Liver Metastases -- Surgery For Non-resectable Metastatic Colorectal Cancer -- Chemotherapy in Patients with Initially Unresectable Liver Metastasis of Colorectal -- Targeted Therapy of Colorectal Cancer Liver Metastasis -- Interventional Treatment of Liver Metastasis of Colorectal Cancer -- Prevention of Postoperative Liver Metastasis by Preoperative Interventional Chemotherapy in Colorectal Cancer -- Establishment of Postoperative Follow up and Database of Colorectal Cancer.
- Format
- e-Book
- Location
- Online
