Antimicrobial Resistance in the 21st Century
https://libcat.nshealth.ca/en/permalink/provcat42795
I.W. Fong, David Shlaes, Karl Drlica, editors.
(Second edition)
--Cham:
Springer
, c2018.
- Available Online
- View e-Book
- Location
- Online
Antimicrobial resistance is now a general problem. Many of us have elderly relatives who died from a drug-resistant infection, and some of us have suffered from a resistant urinary infection that likely came from intestinal bacteria following antibiotic consumption. Antimicrobial Resistance in the 21st Century provides a broad introduction to the subject in which the situation with problematic pathogens is detailed, the biology of resistance is described, and gaining approval for new antibiotic…
- Available Online
- View e-Book
- Other Authors
- Fong, I.W. (Ignatius W.)
- Shlaes, David
- Drlica, Karl
- Responsibility
- I.W. Fong, David Shlaes, Karl Drlica, editors
- Edition
- Second edition
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2018
- Physical Description
- 1 online resource (xviii, 775 p.) : 106 illus., 74 illus. in color
- Series Title
- Emerging infectious diseases of the 21st century
- ISBN
- 9783319785387
- 9783319785370 (print ed.)
- 9783319785394 (print ed.)
- Subjects (MeSH)
- Communicable Diseases - epidemiology
- Communicable Diseases, Emerging
- Drug Resistance, Microbial
- Specialty
- Infectious Disease Medicine
- Pharmacology
- Abstract
- Antimicrobial resistance is now a general problem. Many of us have elderly relatives who died from a drug-resistant infection, and some of us have suffered from a resistant urinary infection that likely came from intestinal bacteria following antibiotic consumption. Antimicrobial Resistance in the 21st Century provides a broad introduction to the subject in which the situation with problematic pathogens is detailed, the biology of resistance is described, and gaining approval for new antibiotics is discussed. Some topics are immediately practical, such as watching for resistant pathogen sub-populations in cultures taken from patients; other topics point to future research efforts that may lead to new antimicrobials and ways to stimulate the action of existing ones. Overall, Antimicrobial Resistance in the 21st Century provides an update for physicians, serves as a starting point for graduate students interested in solving the resistance problem, and may serve as a text for a course on resistance. Lay readers familiar with microbiology will gain an appreciation for a medical issue that promises to be one of the most important of our time.
- Contents
- 1. Introduction: Coordinated Global Action is Needed to Combat Antimicrobial Resistance -- Part I: Examples of Resistance -- 2. Antimicrobial Resistance Among Streptococcus pneumoniae -- 3. Emergence of MRSA in the Community -- 4. Resistance of Gram-negative Bacilli to Antimicrobials -- 5. Drug Resistance in Tuberculosis -- 6. Anaerobic Bacteria: Antimicrobial Susceptibility Testing and Resistance Patterns -- 7. Clinical Significance and Biologic Basis of HIV Drug Resistance -- 8. Resistance of Herpesviruses to Antiviral Agents -- 9. Heteroresistance: A Harbinger of Future Resistance -- Part II: Biology of Resistance -- 10. Epidemiology of Bacterial Resistance -- 11. Transmissible Antibiotic Resistance -- 12. Antibiotics and Resistance in the Environment -- 13. Phenotypic Tolerance and Bacterial Persistence -- 14. Staphylococcus aureus Adaptation During Infection -- 15. Bacterial Signal Transduction Systems in Antimicrobial Resistance -- 16. Fluoroquinolone Interactions with Bacterial Type II Topoisomerases and Target-mediated Drug Resistance -- Part III: Finding New Antimicrobials -- 17. Natural Products in Antibiotic Discovery -- 18. The New vs. Old Target Debate For Drug Discovery -- 19. Non-quinolone Topoisomerase Inhibitors -- 20. Antimicrobial-Mediated Bacterial Suicide -- 21. PK/PD-based Prediction of "Anti-mutant" Antibiotic Exposures Using In Vitro Dynamic Models -- Part IV: Bringing Compounds to Market -- 22. The Role of Pharmacometrics in the Development of Antimicrobial Agents -- 23. New Regulatory Pathways for Antibacterial Drugs -- 24. Economic Incentives for Antibacterial Drug Development: Alternative Market Structures to Promote Innovation.
- Format
- e-Book
- Location
- Online
Epidemiology and prevention of vaccine-preventable diseases
https://libcat.nshealth.ca/en/permalink/provcat27541
Hamborsky J, Kroger A, Wolfe S, eds.
(13th edition)
--Washington, DC:
Public Health Foundation
, 2015.
- Available Online
- View e-Book
- Location
- Online
- Available Online
- View e-Book
- Corporate Author
- National Center for Immunization and Respiratory Diseases
- Responsibility
- Hamborsky J, Kroger A, Wolfe S, eds.
- Edition
- 13th edition
- Alternate Title
- Pink book : course textbook
- Place of Publication
- Washington, DC
- Publisher
- Public Health Foundation
- Date of Publication
- 2015
- Physical Description
- 1 online resource
- Specialty
- Infectious Disease Medicine
- Notes
- 2017 supplement available.
- Contents
- 1. Principles of Vaccination -- 2. General Recommendations on Immunization -- 3. Immunization Strategies for Healthcare Practices and Providers -- 4. Vaccine Safety -- 5. Vaccine Storage and Handling -- 6. Vaccine Administration -- 7. Diphtheria -- 8. Haemophilus influenzae -- 9. Hepatitis A -- 10. Hepatitis B -- 11. Human Papillomavirus -- 12. Influenza -- 13. Measles -- 14. Meningococcal Disease -- 15. Mumps -- 16. Pertussis -- 17. Pneumococcal Disease -- 18. Poliomyelitis -- 19. Rotavirus -- 20. Rubella -- 21. Tetanus -- 22. Varicella -- Appendix A: Schedules and Recommendations -- Appendix B: Vaccines -- Appendix C: Vaccine Information Statements -- Appendix D: Vaccine Safety -- Appendix E: Data and Statistics -- Appendix F: Immunization Resources.
- Format
- e-Book
- Location
- Online
Infectious Disease Informatics : Syndromic Surveillance for Public Health and BioDefense
https://libcat.nshealth.ca/en/permalink/provcat40921
Hsinchun Chen, Daniel Zeng, Ping Yan.
--New York, NY:
Springer
, c2010.
- Available Online
- View e-Book
- Location
- Online
Computer-based infectious disease surveillance systems are capable of real-time or near real-time detection of serious illnesses and potential bioterrorism agent exposures and represent a major step forward in disease surveillance. Infectious Disease Informatics: Syndromic Surveillance for Public Health and Bio-Defense is an in-depth monograph that analyzes and evaluates the outbreak modeling and detection capabilities of existing surveillance systems under a unified framework, and presents the…
- Available Online
- View e-Book
- Author
- Chen, Hsinchun
- Other Authors
- Zeng, Daniel
- Yan, Ping
- Responsibility
- Hsinchun Chen, Daniel Zeng, Ping Yan
- Place of Publication
- New York, NY
- Publisher
- Springer
- Date of Publication
- c2010
- Physical Description
- 1 online resource (xxiv, 210 p. : 68 illus.)
- Series Vol.
- 21
- Series Title
- Integrated Series in Information Systems
- ISBN
- 9781441912787
- 9781441912770 (print ed.)
- ISSN
- 1571-0270
- Subjects (MeSH)
- Medical Informatics - methods
- Communicable Diseases - epidemiology
- Population Surveillance - methods
- Abstract
- Computer-based infectious disease surveillance systems are capable of real-time or near real-time detection of serious illnesses and potential bioterrorism agent exposures and represent a major step forward in disease surveillance. Infectious Disease Informatics: Syndromic Surveillance for Public Health and Bio-Defense is an in-depth monograph that analyzes and evaluates the outbreak modeling and detection capabilities of existing surveillance systems under a unified framework, and presents the first book-length coverage of the subject from an informatics-driven perspective. Individual chapters consider the state of the art, including the facilitation of data collection, sharing and transmission; a focus on various outbreak detection methods; data visualization and information dissemination issues; and system assessment and other policy issues. Eight chapters then report on several real-world case studies, summarizing and comparing eight syndromic surveillance systems, including those that have been adopted by many public health agencies (e.g., RODS and BioSense). The book concludes with a discussion of critical issues and challenges, with a look to future directions. This book is an excellent source of current information for researchers in public health and IT. Government public health officials and private-sector practitioners in both public health and IT will find the most up-to-date information available, and students from a variety of disciplines, including public health, biostatistics, information systems, computer science, and public administration and policy will get a comprehensive look at the concepts, techniques, and practices of syndromic surveillance.
- Contents
- Part I. SYNDROMIC SURVEILLANCE SYSTEMS -- Infectious Disease Informatics: An Introduction and An Analysis Framework -- Public Health Syndromic Surveillance Systems -- Syndromic Surveillance Data Sources and Collection Strategies -- Data Analysis and Outbreak Detection -- Data Visualization, Information Dissemination, and Alerting -- System Assessment and Evaluation -- Part II. SYNDROMIC SURVEILLANCE SYSTEM CASE STUDIES -- BioSense -- RODS -- BioPortal -- ESSENCE -- New York City Syndromic Surveillance Systems -- EARS -- Argus -- HealthMap -- Challenges and Future Directions.
- Format
- e-Book
- Location
- Online
Notifiable diseases on-line
https://libcat.nshealth.ca/en/permalink/provcat34530
Public Health Agency of Canada. Centre for Infectious Disease Prevention and Control.
--[Ottawa, ON]:
Public Health Agency of Canada
- Available Online
- View Database
- Location
- Online
- Available Online
- View Database
- Corporate Author
- Public Health Agency of Canada. Centre for Infectious Disease Prevention and Control
- Place of Publication
- [Ottawa, ON]
- Publisher
- Public Health Agency of Canada
- Format
- Database
- Location
- Online
Viral infections of humans : epidemiology and control
https://libcat.nshealth.ca/en/permalink/provcat33364
Richard A. Kaslow, Lawrence R. Stanberry, James W. LeDuc, editors.
(Fifth edition)
--New York:
Springer
, c2014.
- Available Online
- View e-Book
- Location
- Online
Striking changes have occurred in the world since the publication of the last edition of Viral Infections of Humans. The global population is rapidly approaching 8 billion; climate change is leading to the introduction of new hosts, vectors and virus diseases heretofore never seen in many parts of the world; technological advances have revolutionized the ability to recognize and characterize viruses new and old; vaccines are altering the epidemiological landscape of the diseases they target, in…
- Available Online
- View e-Book
- Other Authors
- Kaslow, Richard A
- Stanberry, Lawrence R
- LeDuc, J. W
- Responsibility
- Richard A. Kaslow, Lawrence R. Stanberry, James W. LeDuc, editors
- Edition
- Fifth edition
- Place of Publication
- New York
- Publisher
- Springer
- Date of Publication
- c2014
- Physical Description
- 1 online resource (xvi, 1215 pages)
- ISBN
- 9781489974488 (electronic bk)
- 9781489974471
- Subjects (MeSH)
- Virus Diseases - epidemiology
- Virus Diseases - prevention & control
- Abstract
- Striking changes have occurred in the world since the publication of the last edition of Viral Infections of Humans. The global population is rapidly approaching 8 billion; climate change is leading to the introduction of new hosts, vectors and virus diseases heretofore never seen in many parts of the world; technological advances have revolutionized the ability to recognize and characterize viruses new and old; vaccines are altering the epidemiological landscape of the diseases they target, in some cases raising the hope of their eradication; and remarkably powerful computational tools are enabling not only detection of outbreaks of disease much sooner than in the past but also, through complex mathematical modeling, more accurate prediction of their potential impact. The new Fifth Edition of Viral Infections of Humans captures both the excitement and frustration of the dynamic struggle between humankind and the viruses that continue to cause immense suffering. It presents the latest concepts, methods, and technologies in epidemiology, detection, investigation, modeling, and intervention. Updated and entirely new chapters by dozens of experts across the field provide analytic summaries of current knowledge of viruses and prions causing acute syndromes, chronic illnesses, and/or malignancies. In sum, this ambitiously expanded volume offers a uniquely comprehensive perspective on viruses in humans, from agents of classic diseases (e.g., hepatitis, measles, polio, rabies, and yellow fever), to those with greatest pandemic impact (e.g., influenza and human immunodeficiency virus), to those discovered relatively recently (e.g., henipavirus, metapneumovirus, and norovirus). The new Fifth Edition of Viral Infections of Humans is an invaluable reference for students, fellows and established professionals in the fields of microbiology, public health and infectious disease epidemiology, medicine, and health policy.
- Contents
- Part I. Concepts & Methods -- 1. Epidemiology and Control: Principles, Practice and Programs -- 2. Diagnosis, Discovery and Dissection of Viral Diseases -- 3. Immunologic Detection and Characterization -- 4. Surveillance and Seroepidemiology -- 5. Viral Dynamics and Mathematical Models -- Part II. Viruses Causing Acute Syndromes -- 6. Adenoviruses -- 7. Alphaviruses: Equine Encephalitis and Others -- 8. Arenaviruses: Lassa Fever, Lujo Hemorrhagic Fever, Lymphocytic Choriomeningitis, and the South American Hemorrhagic Fevers -- 9. Bunyaviruses: Hantavirus and Others -- 10. Coronaviruse -- 11. Enteroviruses and Parechoviruses: Echoviruses, Coxsackieviruses, and Others -- 12. Enteroviruses: Enterovirus 71 -- 13. Enteroviruses: Polio -- 14. Filoviruses: Marburg and Ebola -- 15. Flaviviruses: Dengue -- 16. Flaviviruses: Yellow Fever, Japanese B, West Nile, and Others -- 17. Hepatitis A Virus -- 18. Hepatitis E Virus -- 19. Influenza Viruses -- 20. Noroviruses, Sapoviruses, and Astroviruses -- 21. Orthopoxviruses: Variola, Vaccinia, Cowpox, and Monkeypox -- 22. Paramyxoviruses: Henipaviruses -- 23. Paramyxoviruses: Measles -- 24. Paramyxoviruses: Mumps -- 25. Paramyxoviruses: Parainfluenza Virus -- 26. Paramyxoviruses: Respiratory Syncytial Virus and Metapneumovirus -- 27. Parvoviruses -- 28. Rhabdovirus: Rabies -- 29. Rhinoviruses -- 30. Rotaviruses -- 31. Rubella Virus -- Part III. Viruses Causing Acute and Chronic Syndromes and/or Malignancy -- 32. Hepatitis viruses: Hepatitis B and Hepatitis D -- 33. Hepatitis viruses: Hepatitis C -- 34. Hepatitis viruses: Hepatocellular Carcinoma -- 35. Human Herpesviruses: Cytomegalovirus -- 36. Human Herpesviruses: Herpes Simplex Types 1 and 2 -- 37. Human Herpesvirus: Human Herpesvirus 6 -- 38. Epstein-Barr Virus (EBV): Infectious Mononucleosis and Other Nonmalignant EBV-Associated Diseases -- 39. Kaposi’s Sarcoma-Associated Herpesvirus: Epidemiology, Biological Characteristics and Pathogenesis -- 40. Human Herpesviruses: Malignant Lymphoma -- 41. Epstein-Barr Virus: Nasopharyngeal Carcinoma and Other Epithelial Tumors -- 42. Human Herpesviruses: Varicella and Herpes Zoster -- 43. Human Immunodeficiency Viruses Types 1 and 2 -- 44. Human Papillomaviruses: Cervical Cancer and Warts -- 45. Human T Cell Leukemia Viruses Types 1 and 2 -- 46. Polyomaviruses: Progressive Multifocal Leukoencephalopathy and Other Diseases -- Part IV. Other Transmissible Agents -- 47. Prion Diseases.
- Format
- e-Book
- Location
- Online
