This book provides unique insights into the issues that drive modified dosing regimens for antibiotics in the critically ill. Leading international authors provide their commentary alongside a summary of existing evidence on how to effectively dose antibiotics. Severe infection frequently necessitates admission to the intensive care unit (ICU). Equally, nosocomial sepsis often complicates the clinical course in ICU. Early, appropriate application of antibiotic therapy remains a cornerstone of e…
The two previous editions of Applied Physiology in Intensive Care Medicine proved extremely successful, and the book has now been revised and split into two volumes to enhance ease of use. This first volume comprises three elements -- "physiological notes," "technical notes," and seminal studies. The physiological notes concisely and clearly capture the essence of the physiological perspectives underpinning our understanding of disease and response to therapy. The technical notes then succinctl…
The two previous editions of Applied Physiology in Intensive Care Medicine proved extremely successful, and the book has now been revised and split into two volumes to enhance ease of use. In this second volume some of the most renowned experts in the field offer detailed reviews on measurement techniques and physiological processes of crucial importance in intensive care medicine. Throughout, a key aim is to help overcome the fundamental unevenness in clinicians' understanding of applied physi…
This book is designed to meet the need for a practically oriented textbook on the rapidly growing field of continuous EEG (cEEG) monitoring. A wide range of key clinical aspects are addressed, with explanation of status epilepticus classification, criteria for institution of monitoring, seizure patterns and their recognition, quantitative EEG analysis, and neuroimaging in patients undergoing cEEG monitoring. The value of cEEG and the nature of cEEG findings in various special situations are the…
This book offers a pragmatic approach to day-to-day metabolic and nutritional care based on physiological considerations. Due to the numerous controversial trials published in the last 15 years, there is no clear guidance for intensive care physicians regarding the metabolic and nutritional management of patients. This has resulted in a return to underfeeding and related complications in most ICUs worldwide as shown by the latest Nutrition Day data. Using a structured, logical approach, the boo…
This text provides a comprehensive, state-of-the-art overview of the diagnosis and management of the critically ill cirrhotic patient. The book reviews recent data about risk factors for acute on chronic liver failure (including infection, renal dysfunction and acute alcoholic hepatitis), profiles the latest treatment strategies for the management of variceal bleeding, ascites, hepatocellular carcinoma and presents current and novel therapies for acute hepatic encephalopathy, and anticoagulatio…
Finding all the information necessary to treat or meet the nutritional requirements of patients who are severely ill or establish new protocols has historically been problematic. This is addressed in Diet and Nutrition in Critical Care. This major reference work encapsulates the latest treatments and procedures to meet the dietary and nutritional needs of the critically ill. Where evidence is available this is presented. However, where evidence is absent, the authors highlight this and provide …
This textbook approaches the study of critical care with teaching in mind. In medicine "teachable moments" usually occur in clinical context, where the engagement in a real case exemplifies principles of diagnosis or therapy. In order to replicate the teaching method, selected cases are presented within each chapter offering the reader an opportunity to process and reflect on the components of the topic within a practical scenario. While medical practice attempts to be evidence-based, common ap…
This book is the first to describe a practical evidence-based approach to the management of critically ill obese patients with various medical or postoperative respiratory problems in the intensive care unit. In brief, the book aims to identify the best strategy and present clinical recommendations for different circumstances, to establish indications for and contraindications to noninvasive and invasive mechanical ventilation, and to offer clear guidance on weaning from mechanical ventilation …
Clinical research in critical care has exploded in the past several years and we now have a much better understanding of how to care for intensive care unit (ICU) patients in areas such as management of sepsis, fluid resuscitation, mechanical ventilation, antibiotic administration, and sedation and analgesia. However, despite improved clinical care, many critically ill patients continue to experience complications of critical illness - some complications are iatrogenic and preventable, while ot…
This text provides a review of the current knowledge in both the mechanics of nourishing the critically ill and the metabolic and immunological roles nutrients play. In-depth chapters discuss disease related malnutrition as distinct from under-or-over nourishment and the impact of nourishment in either form of malnutrition. The appropriate timing and indications for nutrition support are provided, as well as advanced techniques for improving practice. A broad range of issues related to interdis…
With the increasing proportion of persons above 65 years old and over with a 50% overall risk of developing cancer during our lifetimes, cancer rates continue to play a role in the utilization of healthcare services—particularly in the ICU. Currently, very few oncologic critical care texts, journals, subspecialty societies in the field, or knowledge about the current availability of oncologic/hematologic ICUs exist. As such, major knowledge gaps exist about outcomes (e.g., ICU utilization, mort…
The Editors and contributors of this book take seriously the statement that 'For all of the science inherent in the specialty of pediatric critical care medicine, there is still art in providing comfort and solace to our patients and their families. No technology will ever replace the compassion in the touch of a hand or the soothing words of a calm and gentle voice.' The four volumes of Pediatric Critical Care Medicine: Basic Science and Clinical Evidence, 2nd Edition detail the continued grow…
The Editors and contributors of this book take seriously the statement that 'For all of the science inherent in the specialty of pediatric critical care medicine, there is still art in providing comfort and solace to our patients and their families. No technology will ever replace the compassion in the touch of a hand or the soothing words of a calm and gentle voice.' The four volumes of Pediatric Critical Care Medicine: Basic Science and Clinical Evidence, 2nd Edition detail the continued grow…
The Editors and contributors of this book take seriously the statement that 'For all of the science inherent in the specialty of pediatric critical care medicine, there is still art in providing comfort and solace to our patients and their families. No technology will ever replace the compassion in the touch of a hand or the soothing words of a calm and gentle voice.' The four volumes of Pediatric Critical Care Medicine: Basic Science and Clinical Evidence, 2nd Edition detail the continued grow…
The Editors and contributors of this book take seriously the statement that For all of the science inherent in the specialty of pediatric critical care medicine, there is still art in providing comfort and solace to our patients and their families. No technology will ever replace the compassion in the touch of a hand or the soothing words of a calm and gentle voice. The four volumes of Pediatric Critical Care Medicine: Basic Science and Clinical Evidence, 2nd Edition detail the continued growth…