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Cushing's Disease

https://libcat.nshealth.ca/en/permalink/provcat30315
edited by Brooke Swearingen, Beverly M. K. Biller. --Boston, MA: Springer Science+Business Media , c2011.
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Location
Online
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Author
Swearingen, Brooke
Other Authors
Biller, Beverly M. K
Responsibility
edited by Brooke Swearingen, Beverly M. K. Biller
Place of Publication
Boston, MA
Publisher
Springer Science+Business Media
Date of Publication
c2011
Series Vol.
31
Series Title
Endocrine updates
ISBN
9781461400110
Subjects (MeSH)
Cushing Syndrome
Subjects (LCSH)
Endocrinology 
Format
e-Book
Location
Online
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Cushing's Syndrome : Pathophysiology, Diagnosis and Treatment

https://libcat.nshealth.ca/en/permalink/provcat28924
edited by Marcello D. Bronstein. --Totowa, NJ: Springer Science+Business Media , c2011.
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Location
Online
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Author
Bronstein, Marcello D
Responsibility
edited by Marcello D. Bronstein
Place of Publication
Totowa, NJ
Publisher
Springer Science+Business Media
Date of Publication
c2011
Series Title
Contemporary endocrinology (Totowa, N.J.)
ISBN
9781603274494
Subjects (MeSH)
Cushing Syndrome
Subjects (LCSH)
Endocrinology 
Format
e-Book
Location
Online
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The Hypothalamic-Pituitary-Adrenal Axis in Health and Disease : Cushing's Syndrome and Beyond

https://libcat.nshealth.ca/en/permalink/provcat41551
Eliza B. Geer, editor. --Cham: Springer , 2017.
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Location
Online
Cushing's syndrome is a rare disorder that is associated with many co-morbidities such as systemic hypertension, diabetes, osteoporosis, impaired immune function, and psychiatric disease, all of which severely reduce quality of life and life expectancy. This book reviews the role of cortisol in the human body, focusing on the effects of excess cortisol due to Cushing's syndrome as well as the role of the HPA axis in metabolism, inflammation, and neuropsychiatric function. The volume will cover …
Available Online
View e-Book
Other Authors
Geer, Eliza B
Responsibility
Eliza B. Geer, editor
Place of Publication
Cham
Publisher
Springer
Date of Publication
2017
Physical Description
1 online resource (vi, 327 pages) : 19 illus., 15 illus. in color
ISBN
9783319459509
9783319459486 (print ed.)
Subjects (MeSH)
Cushing Syndrome - metabolism
Cushing Syndrome - therapy
Glucocorticoids - metabolism
Hypothalamo-Hypophyseal System - physiology
Pituitary-Adrenal System - physiology
Abstract
Cushing's syndrome is a rare disorder that is associated with many co-morbidities such as systemic hypertension, diabetes, osteoporosis, impaired immune function, and psychiatric disease, all of which severely reduce quality of life and life expectancy. This book reviews the role of cortisol in the human body, focusing on the effects of excess cortisol due to Cushing's syndrome as well as the role of the HPA axis in metabolism, inflammation, and neuropsychiatric function. The volume will cover basic mechanistic data, clinical outcomes data, and novel therapies. Also discussed are everything from abnormalities of the HPA axis, to the role of the HPA axis in the development of neuropsychiatric disorders and metabolic disorders, to new definitions of Cushing's remission and recurrence. The Hypothalamic Pituitary Adrenal Axis in Health and Disease will provide a comprehensive and multi-disciplinary review of the pathophysiology and outcomes of excess cortisol in the human body and brain as well as the role of the HPA axis in other disease states.
Contents
Part I: Hypothalamic-Pituitary-Adrenal Axis Regulation of the Body, Brain, and Inflammation -- Glucocorticoid Regulation of Body Composition and Metabolism -- Glucocorticoid Regulation of Neurocognitive and Neuropsychiatric Function -- Glucocorticoids: Inflammation and Immunity -- Part II: Cushing’s Syndrome -- Molecular Pathogenesis of Primary Adrenal Cushing’s Syndrome -- Pathogenesis and Treatment of Aggressive Corticotroph Pituitary Tumors -- Neoplastic/Pathological and Nonneoplastic/Physiological Hypercortisolism: Cushing Versus Pseudo-Cushing Syndromes -- Imaging Strategies for Localization of ACTH-Secreting Tumors -- Surgical Treatment of Cushing’s Disease -- Medical Therapies in Cushing’s Syndrome -- Mild Adrenal Cortisol Excess -- Long-Term Effects of Prior Cushing’s Syndrome -- Cushing’s Disease, Refining the Definition of Remission and Recurrence -- Part III: Beyond Cushing’s: Glucocorticoid Sensitivity, Regulation, and the Metabolic Syndrome -- Primary Generalized Glucocorticoid Resistance or Chrousos Syndrome: Allostasis Through a Mutated Glucocorticoid Receptor -- Cortisol Metabolism as a Regulator of the Tissue-Specific Glucocorticoid Action -- Obesity and Metabolic Syndrome: A Phenotype of Mild Long-Term Hypercortisolism?
Format
e-Book
Location
Online
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