topic:"Diabetes Mellitus, Type 1 - drug therapy" found 2 records - Provincial Hospitals Library Catalogue

Revise Search

Help

Narrow By

Print PDF

2 records – page 1 of 1.

Diabetes & C-Peptide : Scientific and Clinical Aspects

https://libcat.nshealth.ca/en/permalink/provcat31009

Anders A.F. Sima, editor. --New York, NY: Humana Press , c2012.

Available Online: View e-Book

Location: Online

In Diabetes & C-Peptide: Scientific and Clinical Aspects, a renowned group of leading researchers and physicians offers a comprehensive overview of the role of C-Peptide in type 1 diabetes. The book is organized in five sections. An Introductory section provides the background and key features of C-peptide's physiological function and how its deficiency contributes to complications. The second section describes up-to-date information on the biochemical and molecular actions of C-peptide, includ…

Available Online: View e-Book

Other Authors: Sima, Anders A.F

Responsibility: Anders A.F. Sima, editor

Place of Publication: New York, NY

Publisher: Humana Press

Date of Publication: c2012

Physical Description: 1 online resource (xiii, 169 p. : 63 ill., 35 ill. in color)

Series Title: Contemporary diabetes

ISBN: 9781617793912

Subjects (MeSH): C-Peptide - physiology; C-Peptide - therapeutic use; Diabetes Complications - prevention & control; Diabetes Mellitus, Type 1 - drug therapy

Subjects (LCSH): Diabetes; Endocrinology; Biochemistry

Abstract: In Diabetes & C-Peptide: Scientific and Clinical Aspects, a renowned group of leading researchers and physicians offers a comprehensive overview of the role of C-Peptide in type 1 diabetes. The book is organized in five sections. An Introductory section provides the background and key features of C-peptide's physiological function and how its deficiency contributes to complications. The second section describes up-to-date information on the biochemical and molecular actions of C-peptide, including membrane binding, interactions with insulin as well as the interaction between C-peptide and zinc and effects on microvascular vasoreactivity. The third section summarizes in vivo animal studies of the type 1 diabetic complications. The fourth section reviews the clinical efforts of C-peptide on inflammation, cardiovascular complication, neuropathy and nephropathy. Finally, in the Conclusions section, a summary of the present state of C-peptide, outstanding questions, and the likely direction of the field are offered. Developed by the foremost investigators in the rapidly moving field of C-peptide research, Diabetes & C-Peptide: Scientific and Clinical Aspects is an important contribution to the literature for all researchers and physicians concerned about type 1 diabetes.

Contents: C-peptide and Insulin: A Happy Marriage -- Peptide Interactions of Proinsulin C-peptide -- The Effect of Combined C-peptide and Zinc on Cellular Function -- C-Peptide Signaling in the Kidney and Protection from Diabetic Nephropathy -- Role of C-Peptide in the Regulation of Microvascular Blood Flow -- Is NO-eNOS a target for C-peptide action and its protective effects on diabetic nephropathy? -- Renoprotective Effects of C-Peptide in Type I Diabetes -- The Mechanisms Underlying the Effects of C-peptide on Type I Diabetic Neuropathy -- C-peptide and Type 1 Diabetic Encephalopathy -- C-peptide: a New Molecule with Anti-Inflammatory Properties -- C-peptide: Connecting Diabetes with Macrovascular Complications -- C-peptide and Diabetic Neuropathy in Patients with Type I Diabetes -- Proatherogenic Effects of C-Peptide -- Conclusions and Future Outlook.