Bisphosphonates and Osteonecrosis of the Jaw : A Multidisciplinary Approach
https://libcat.nshealth.ca/en/permalink/provcat31225
Francesco Saverio De Ponte, editor ; foreword by Giorgio Iannetti.
--Milan:
Springer
, c2012.
- Available Online
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- Location
- Online
Bisphosphonates are commonly prescribed to inhibit bone loss in patients with osteoporosis, as well as osteopenia, cancer, and Paget's disease of the bone. Recently, scientific literature has addressed a possible relationship between bisphosphonates and osteonecrosis of the jaw (ONJ). It is important to note that though the risks for developing ONJ are much higher for cancer patients on intravenous bisphosphonate therapy (used to reduce bone pain), the occurrence of ONJ also in patients treated…
- Available Online
- View e-Book
- Author
- De Ponte, Francesco Saverio
- Responsibility
- Francesco Saverio De Ponte, editor ; foreword by Giorgio Iannetti
- Place of Publication
- Milan
- Publisher
- Springer
- Date of Publication
- c2012
- Physical Description
- 1 online resource (xiii, 181 p. : 98 ill., 76 ill. in color)
- ISBN
- 9788847020832
- Subjects (MeSH)
- Bisphosphonate-Associated Osteonecrosis of the Jaw - etiology
- Bisphosphonate-Associated Osteonecrosis of the Jaw - therapy
- Diphosphonates - adverse effects
- Subjects (LCSH)
- Dentistry
- Pharmacy
- Family medicine
- Radiology, Medical
- Hematology
- Surgery
- Abstract
- Bisphosphonates are commonly prescribed to inhibit bone loss in patients with osteoporosis, as well as osteopenia, cancer, and Paget's disease of the bone. Recently, scientific literature has addressed a possible relationship between bisphosphonates and osteonecrosis of the jaw (ONJ). It is important to note that though the risks for developing ONJ are much higher for cancer patients on intravenous bisphosphonate therapy (used to reduce bone pain), the occurrence of ONJ also in patients treated with oral BF for osteoporosis has been also highlighted, though rarely. On the basis of the large use of BF, of their pharmacokinetics, of the systemic and local risk factors, physicians prescribing them and dental surgeons should be well informed on the various aspects of the problem. Aim of this volume is to offer an update on the current status of prevention, and on the current conservative and surgical treatments. The multidisciplinary approach will be very much appreciated by GP's, the different specialists using bisphosphonates and by dental surgeons.
- Format
- e-Book
- Location
- Online
Bisphosphonates in Medical Practice : Actions : Side Effects : Indications : Strategies
https://libcat.nshealth.ca/en/permalink/provcat28438
by Reiner Bartl, Bertha Frisch, Emmo Tresckow, Christoph Bartl.
--Berlin, Heidelberg:
Springer-Verlag
, c2007.
- Available Online
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- Location
- Online
- Available Online
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- Author
- Bartl, Reiner
- Other Authors
- Frisch, Bertha
- Tresckow, Emmo
- Bartl, Christoph
- Responsibility
- by Reiner Bartl, Bertha Frisch, Emmo Tresckow, Christoph Bartl
- Place of Publication
- Berlin, Heidelberg
- Publisher
- Springer-Verlag
- Date of Publication
- c2007
- ISBN
- 9783540698708
- Subjects (MeSH)
- Bone Diseases - drug therapy
- Diphosphonates - adverse effects
- Diphosphonates - therapeutic use
- Subjects (LCSH)
- Biochemistry
- Orthopedics
- Format
- e-Book
- Location
- Online
Medication-Related Osteonecrosis of the Jaws : Bisphosphonates, Denosumab, and New Agents
https://libcat.nshealth.ca/en/permalink/provcat39416
Sven Otto, editor.
--Berlin, Heidelberg:
Springer
, c2015.
- Available Online
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- Location
- Online
Osteonecrosis of the jaws is a well-known side-effect of antiresorptive therapy that predominantly occurs in patients suffering from malignant diseases and receiving intravenous administrations of nitrogen-containing bisphosphonates or subcutaneous administrations of denosumab, a monoclonal antibody. Less frequently it may also be observed in patients with osteoporosis who are being treated with these antiresorptive drugs. This textbook provides detailed, up-to-date information on all aspects o…
- Available Online
- View e-Book
- Other Authors
- Otto, Sven
- Responsibility
- Sven Otto, editor
- Place of Publication
- Berlin, Heidelberg
- Publisher
- Springer
- Date of Publication
- c2015
- Physical Description
- 1 online resource (viii, 220 p. : 83 illus., 63 illus. in color)
- ISBN
- 9783662437339
- 9783662437322 (print ed.)
- Subjects (MeSH)
- Antibodies, Monoclonal, Humanized - adverse effects
- Bisphosphonate-Associated Osteonecrosis of the Jaw
- Diphosphonates - adverse effects
- Drug-Related Side Effects and Adverse Reactions
- Jaw - drug effects
- Abstract
- Osteonecrosis of the jaws is a well-known side-effect of antiresorptive therapy that predominantly occurs in patients suffering from malignant diseases and receiving intravenous administrations of nitrogen-containing bisphosphonates or subcutaneous administrations of denosumab, a monoclonal antibody. Less frequently it may also be observed in patients with osteoporosis who are being treated with these antiresorptive drugs. This textbook provides detailed, up-to-date information on all aspects of medication-related osteonecrosis of the jaws, including clinical features, pathogenesis, treatment options, and preventive measures. It also explains safe prevention and treatment strategies for patients receiving antiresorptive drugs who require extractions, implant insertions, and other dento-alveolar surgeries. This book will be of major interest for medical and dental students, dentists, and oral and maxillofacial surgeons as well as osteologists and oncologists.
- Contents
- 1. Pharmacological Aspects of Antiresorptive Drugs: Bisphosphonates and Denosumab -- 2. Bisphosphonate and Denosumab Therapy: Fields of Application -- 3. Risk Factors for Medication-Related Osteonecrosis of the Jaw -- 4. Definition, Clinical Features and Staging of Medication- Related Osteonecrosis of the Jaw -- 5 Epidemiology of Medication- Related Osteonecrosis of the Jaw -- 6. Imaging Modalities and Characteristics in Medication-Related Osteonecrosis of the Jaw -- 7. Treatment of Medication- Related Osteonecrosis of the Jaw -- 8. Local and Microvascular Free Flaps in Patients with Medication-Related Osteonecrosis of the Jaw -- 9. Adjuvant Treatment Options in the Management of Medication-Related Osteonecrosis of the Jaw -- 10 New and Innovative Treatment Strategies for Medication-Related Osteonecrosis of the Jaw -- 11. Microbiology and Antibiotics in the Context of Medication-Related Osteonecrosis of the Jaw -- 12. Histopathology of Medication-Related Osteonecrosis of the Jaw -- 13. Pathogenesis of Medication- Related Osteonecrosis of the Jaw -- 14. Risk Reduction of Medication-Related Osteonecrosis of the Jaw -- 15. Animal Models of Medication-Related Osteonecrosis of the Jaw --- 16. Dental Rehabilitation in Patients Receiving Antiresorptive Drugs -- 17. Dental Implants in the Context Antiresorptive Drugs and Medication-Related Osteonecrosis of the Jaw -- 18. Osteonecrosis of the Jaw in Association with Targeted Therapy -- 19. History of Osteonecrosis of the Jaw -- 20. Future Perspectives of Bisphosphonates in Maxillofacial, Dental, and Medical Practice.
- Format
- e-Book
- Location
- Online
