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Optimizing Breast Cancer Management

https://libcat.nshealth.ca/en/permalink/provcat43324
William J. Gradishar, editor. --Cham: Springer , c2018.
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This book presents expert opinions on a variety of key topics related to the management of breast cancer, with a focus on the implications of recent advances and research findings for clinical practice. It also explores the controversy regarding mammography screening and reviews the contribution of new imaging modalities. Considerable attention is paid to developments in surgical procedures, including the potential for the safe and effective use of sentinel lymph node dissection alone--even in …
Available Online
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Other Authors
Gradishar, William J.
Responsibility
William J. Gradishar, editor
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2018
Physical Description
1 online resource (v, 189 p.) : 11 illus. in color
Series Vol.
173
Series Title
Cancer treatment and research
ISBN
9783319701974
9783319701950 (print ed.)
9783319701967 (print ed.)
9783319889016 (print ed.)
ISSN
0927-3042
Subjects (MeSH)
Antineoplastic Agents
Breast Neoplasms
Combined Modality Therapy
Early Detection of Cancer
Specialty
Gynecology
Medical Oncology
Abstract
This book presents expert opinions on a variety of key topics related to the management of breast cancer, with a focus on the implications of recent advances and research findings for clinical practice. It also explores the controversy regarding mammography screening and reviews the contribution of new imaging modalities. Considerable attention is paid to developments in surgical procedures, including the potential for the safe and effective use of sentinel lymph node dissection alone--even in patients with positive nodes--and to the advantages and contraindications of new radiotherapy techniques. Genetic aspects are discussed in detail, including an assessment of the role of genetic testing and the potential impact of genetic signatures on breast cancer management. New systemic strategies, such as anti-HER2 therapy, endocrine agents, and agents to reverse endocrine resistance, are considered, and the optimal use of chemotherapy for early-stage and advanced-stage disease is addressed. In closing, the book shares important new insights into lifestyle risk factors, risk reduction strategies, and survivor issues, including sexual dysfunction and fertility maintenance.
Contents
Strategies to maintain fertility in young breast cancer patients -- Sexual dysfuncton in breast cancer survivors -- The breast cancer screening conundrum -- New imaging modalities in breast cancer -- Is DCIS over treated -- "Personalizing" breast radiation -- Management of the axilla in early stage breast cancer -- Management of the breast in denovo MBC -- Identification of genetic lesions in patients with strong family history and no BRCA mutation -- Managing "testing expectations" in breast cancer survivors -- The role of bone strengthening agents in early and advanced disease -- Overcoming endocrine resistance -- Optimal Adjuvant endocrine therapy -- Choosing wisely in HER2 positive metastatic breast cancer -- Should early stage, triple negative breast cancer be treated with preoperative systemic therapy?
Format
e-Book
Location
Online
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Uterine Fibroids and Adenomyosis

https://libcat.nshealth.ca/en/permalink/provcat43080
Norihiro Sugino, editor. --Singapore: Springer , c2018.
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This volume elucidates state-of-the-art findings of uterine fibroids and adenomyosis, incorporating expert basic knowledge. Uterine fibroids and adenomyosis are common uterine tumors in reproductive-age women. However, the pathogenesis of the tumors is still poorly understood, and both genetic and environmental factors may be involved in their generation or development. Recent research on the genomics and molecular biology of uterine fibroids and adenomyosis has facilitated a better understandi…
Available Online
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Other Authors
Sugino, Norihiro
Responsibility
Norihiro Sugino, editor
Place of Publication
Singapore
Publisher
Springer
Date of Publication
c2018
Physical Description
1 online resource (vii, 173 p.) : 40 illus., 29 illus. in color
Series Title
Comprehensive gynecology and obstetrics
ISBN
9789811071676
9789811071669 (print ed.)
9789811071683 (print ed.)
ISSN
2364-1932
Subjects (MeSH)
Leiomyoma
Adenomyosis
Specialty
Gynecology
Abstract
This volume elucidates state-of-the-art findings of uterine fibroids and adenomyosis, incorporating expert basic knowledge. Uterine fibroids and adenomyosis are common uterine tumors in reproductive-age women. However, the pathogenesis of the tumors is still poorly understood, and both genetic and environmental factors may be involved in their generation or development. Recent research on the genomics and molecular biology of uterine fibroids and adenomyosis has facilitated a better understanding of the pathogenesis and pathophysiology of these benign tumors. Renowned experts provide detailed discussions of basic research and clinical aspects of uterine fibroids and adenomyosis in this book, from histopathology and molecular pathogenesis to diagnosis and the latest treatment of uterine fibroids, including pregnancy complications of adenomyosis. A great deal of information and a deep understanding of molecular and genetic biology have led to development of more innovative treatments of these tumors. Thus this book benefits not only oncologists, seasoned gynecologists, and obstetricians, but also molecular biologists and other basic researchers who are involved in the treatment of uterine fibroids.
Contents
1. Histopathology of uterine fibroids -- 2. Genetics and genomics of uterine fibroids -- 3. Molecular pathogenesis of uterine fibroids -- 4. Stem cells and uterine fibroids -- 5. Epigenetics and uterine fibroids -- 6. Biomarkers of uterine fibroids -- 7. Current medical treatments for uterine fibroids -- 8. Diagnostic imaging for uterine fibroids, adenomyosis and uterine sarcomas -- 9. Pathogenesis of adenomyosis -- 10. Adenomyosis and subfertility -- 11. Surgical treatments for adenomyosis -- 12. Pregnancy complications of adenomyosis.
Format
e-Book
Location
Online
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